Phosphodiesterase

Overview


Name	Phosphodiesterase
Smed ID	SMED30002297
Length (bp)	2253

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Phosphodiesterase (SMED30002297) t-SNE clustered cells

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30002297) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phosphodiesterase (SMED30002297) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phosphodiesterase (SMED30002297) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002297

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30002297	h1SMcG0022295	Contig54772	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002297	h1SMcG0022295	Contig54772	newmark_ests	PMID:29674431 Fincher et al., 2018
gut	SMED30002297	h1SMcG0022295	dd_Smed_v4_6991_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior side	SMED30002297	h1SMcG0022295	dd_Smed_v4_6991_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30002297	h1SMcG0022295	dd_Smed_v4_6991_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30002297	h1SMcG0022295	dd_Smed_v6_6991_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30002297	h1SMcG0022295	dd_Smed_v4_6991_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE9A (phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795])

HSP 1 Score: 318.931 bits (816), Expect = 7.622e-101
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:   94 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 394

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE9A (phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795])

HSP 1 Score: 320.087 bits (819), Expect = 7.684e-101
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  126 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 426

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE9A (phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795])

HSP 1 Score: 319.316 bits (817), Expect = 1.056e-100
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  120 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 420

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE9A (phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795])

HSP 1 Score: 319.701 bits (818), Expect = 1.136e-100
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  127 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 427

[Close]

BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE9A (phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:8795])

HSP 1 Score: 320.087 bits (819), Expect = 1.702e-100
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  152 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 452

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-1 (Probable 3',5'-cyclic phosphodiesterase pde-1 [Source:UniProtKB/Swiss-Prot;Acc:O18696])

HSP 1 Score: 184.882 bits (468), Expect = 2.850e-50
Identity = 108/330 (32.73%), Postives = 179/330 (54.24%), Query Frame = 3

Query:  846 WSFSDAELINLVK---LMFINLQL------TTAFNIPLTTLDQWLFSV---YQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVF------------------PSVEDLILKPVKNQLEYYTKLQNKASNPTA 1745
            WSFS  +L  + +   L ++  +L         F +PLT L+ +L ++   Y  +N  P+HN  HA  V Q  + M++   L      LE+L ++F AL HD +H G  N F I +++  A  YND+S LENHH +  F++++E  +NIL HLT  ++K+LR + I+ +L+TDM+ H   +   +++L   + ++ +      + +++  CDIS+ A+P ++ E W E +LEEFF+Q DLE   GLP++P  DR  V  ++SQ GFI F++ P   + GE+                   PSV+    K   N L     L+N +++P++
Sbjct:  143 WSFSPFQLNEVSEGHALKYVGFELFNRYGFMDRFKVPLTALENYLSALEVGYSKHNN-PYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPEGIDKNK----ALCLIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFIVEPTMVVCGELLVKMVEPLVSLPPTDSLFPPSVDGGDDKSPSNALSPLPDLRNSSTSPSS 467

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-1 (Probable 3',5'-cyclic phosphodiesterase pde-1 [Source:UniProtKB/Swiss-Prot;Acc:O18696])

HSP 1 Score: 186.808 bits (473), Expect = 4.872e-50
Identity = 108/330 (32.73%), Postives = 179/330 (54.24%), Query Frame = 3

Query:  846 WSFSDAELINLVK---LMFINLQL------TTAFNIPLTTLDQWLFSV---YQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVF------------------PSVEDLILKPVKNQLEYYTKLQNKASNPTA 1745
            WSFS  +L  + +   L ++  +L         F +PLT L+ +L ++   Y  +N  P+HN  HA  V Q  + M++   L      LE+L ++F AL HD +H G  N F I +++  A  YND+S LENHH +  F++++E  +NIL HLT  ++K+LR + I+ +L+TDM+ H   +   +++L   + ++ +      + +++  CDIS+ A+P ++ E W E +LEEFF+Q DLE   GLP++P  DR  V  ++SQ GFI F++ P   + GE+                   PSV+    K   N L     L+N +++P++
Sbjct:  274 WSFSPFQLNEVSEGHALKYVGFELFNRYGFMDRFKVPLTALENYLSALEVGYSKHNN-PYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPEGIDKNK----ALCLIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFIVEPTMVVCGELLVKMVEPLVSLPPTDSLFPPSVDGGDDKSPSNALSPLPDLRNSSTSPSS 598

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 179.874 bits (455), Expect = 4.881e-48
Identity = 96/279 (34.41%), Postives = 160/279 (57.35%), Query Frame = 3

Query:  906 LTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPK----------LDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYY 1709
            L   F I  +TL  +L ++  +Y    +HNF HA  V Q ++ ++    L E+F  LE+L  +F+   HD+DHPG  N + IN+   LA  YND+S LE HH A+AF++L++   + L +L+ KQ  + R+I I  +L+TDM+KH  ++ + + ++            LD  ND   +I ++  +I L D+SN  +P  + + W + ++EE+++Q D EK  GL  +P  DR  VT   SQ GFI +++ PL+E + + V+P  ++ IL  ++   E+Y
Sbjct:  304 LFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYND---KIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQN-ILDQLEENREWY 578

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 178.718 bits (452), Expect = 5.174e-48
Identity = 96/279 (34.41%), Postives = 160/279 (57.35%), Query Frame = 3

Query:  906 LTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPK----------LDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYY 1709
            L   F I  +TL  +L ++  +Y    +HNF HA  V Q ++ ++    L E+F  LE+L  +F+   HD+DHPG  N + IN+   LA  YND+S LE HH A+AF++L++   + L +L+ KQ  + R+I I  +L+TDM+KH  ++ + + ++            LD  ND   +I ++  +I L D+SN  +P  + + W + ++EE+++Q D EK  GL  +P  DR  VT   SQ GFI +++ PL+E + + V+P  ++ IL  ++   E+Y
Sbjct:  254 LFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYND---KIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQN-ILDQLEENREWY 528

[Close]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000])

HSP 1 Score: 179.874 bits (455), Expect = 8.172e-48
Identity = 96/279 (34.41%), Postives = 160/279 (57.35%), Query Frame = 3

Query:  906 LTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPK----------LDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYY 1709
            L   F I  +TL  +L ++  +Y    +HNF HA  V Q ++ ++    L E+F  LE+L  +F+   HD+DHPG  N + IN+   LA  YND+S LE HH A+AF++L++   + L +L+ KQ  + R+I I  +L+TDM+KH  ++ + + ++            LD  ND   +I ++  +I L D+SN  +P  + + W + ++EE+++Q D EK  GL  +P  DR  VT   SQ GFI +++ PL+E + + V+P  ++ IL  ++   E+Y
Sbjct:  331 LFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYND---KIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQN-ILDQLEENREWY 605

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde9 (gene:FBgn0259171 transcript:FBtr0333524)

HSP 1 Score: 332.798 bits (852), Expect = 5.367e-98
Identity = 163/344 (47.38%), Postives = 231/344 (67.15%), Query Frame = 3

Query:  810 VRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGT 1841
            VR  L+  +F+ + +SDA++I+L++ MF+ L     F+IP+ TL +WL+ VY++YN VPFHNF H FCV QM+YA+   ANL      LE L L+ S + HDLDHPG NN +QINART LA RYND SPLENHHC++AF++LE  + NI K+ +   F  +RE  I+CIL+TDM +H +I+T+F  + P  D  N  +H  +L +++IK+ DISNEARP  ++EPWL+ LL+EFF QS  EK +GLP  PFMD +KV+K  SQ  FI  V++PLFE  GE+ P + +LI+ PV+  LEYY +L N A   T  +++     SN +    +++G+I S  + + T
Sbjct:  680 VRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN-RAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL-NDAQTKTRKSVAD----SNTSATSDSNSGTIDSNAAMVST 1017

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde9 (gene:FBgn0259171 transcript:FBtr0299635)

HSP 1 Score: 332.798 bits (852), Expect = 5.367e-98
Identity = 163/344 (47.38%), Postives = 231/344 (67.15%), Query Frame = 3

Query:  810 VRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGT 1841
            VR  L+  +F+ + +SDA++I+L++ MF+ L     F+IP+ TL +WL+ VY++YN VPFHNF H FCV QM+YA+   ANL      LE L L+ S + HDLDHPG NN +QINART LA RYND SPLENHHC++AF++LE  + NI K+ +   F  +RE  I+CIL+TDM +H +I+T+F  + P  D  N  +H  +L +++IK+ DISNEARP  ++EPWL+ LL+EFF QS  EK +GLP  PFMD +KV+K  SQ  FI  V++PLFE  GE+ P + +LI+ PV+  LEYY +L N A   T  +++     SN +    +++G+I S  + + T
Sbjct:  680 VRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN-RAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL-NDAQTKTRKSVAD----SNTSATSDSNSGTIDSNAAMVST 1017

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde9 (gene:FBgn0259171 transcript:FBtr0333525)

HSP 1 Score: 332.798 bits (852), Expect = 5.367e-98
Identity = 163/344 (47.38%), Postives = 231/344 (67.15%), Query Frame = 3

Query:  810 VRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGT 1841
            VR  L+  +F+ + +SDA++I+L++ MF+ L     F+IP+ TL +WL+ VY++YN VPFHNF H FCV QM+YA+   ANL      LE L L+ S + HDLDHPG NN +QINART LA RYND SPLENHHC++AF++LE  + NI K+ +   F  +RE  I+CIL+TDM +H +I+T+F  + P  D  N  +H  +L +++IK+ DISNEARP  ++EPWL+ LL+EFF QS  EK +GLP  PFMD +KV+K  SQ  FI  V++PLFE  GE+ P + +LI+ PV+  LEYY +L N A   T  +++     SN +    +++G+I S  + + T
Sbjct:  680 VRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN-RAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL-NDAQTKTRKSVAD----SNTSATSDSNSGTIDSNAAMVST 1017

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde9 (gene:FBgn0259171 transcript:FBtr0330395)

HSP 1 Score: 332.798 bits (852), Expect = 9.021e-98
Identity = 163/344 (47.38%), Postives = 231/344 (67.15%), Query Frame = 3

Query:  810 VRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGT 1841
            VR  L+  +F+ + +SDA++I+L++ MF+ L     F+IP+ TL +WL+ VY++YN VPFHNF H FCV QM+YA+   ANL      LE L L+ S + HDLDHPG NN +QINART LA RYND SPLENHHC++AF++LE  + NI K+ +   F  +RE  I+CIL+TDM +H +I+T+F  + P  D  N  +H  +L +++IK+ DISNEARP  ++EPWL+ LL+EFF QS  EK +GLP  PFMD +KV+K  SQ  FI  V++PLFE  GE+ P + +LI+ PV+  LEYY +L N A   T  +++     SN +    +++G+I S  + + T
Sbjct:  680 VRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN-RAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL-NDAQTKTRKSVAD----SNTSATSDSNSGTIDSNAAMVST 1017

[Close]

BLAST of Phosphodiesterase vs. Ensembl Fly
Match: dnc (gene:FBgn0000479 transcript:FBtr0070522)

HSP 1 Score: 176.407 bits (446), Expect = 3.132e-47
Identity = 100/304 (32.89%), Postives = 172/304 (56.58%), Query Frame = 3

Query:  837 FNMWSFS-DAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNY-NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLL-------PKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYYTKL 1718
            F++  FS +  L  +   +F + +L T+  IP  T   ++ ++  +Y    PFHN  HA  V Q    ++N   L  +F  LE+   +F+A  HD+DHPGL N F +N+ + LA  YND+S LENHH A+AF++L+ +  +I  ++  KQ + LR++ I  +LSTDM+KH  ++ + + ++         + L+++ + RI ++  ++   D+SN  +P  + + W+  L+EEFF Q D E+  G+  +P  DR   T   SQ GFI +++ PL+E + + V P  +D IL  ++   +YY  +
Sbjct:  130 FSIGEFSVNRPLTCVAYTIFQSRELLTSLMIPPKTFLNFMSTLEDHYVKDNPFHNSLHAADVTQSTNVLLNTPALEGVFTPLEVGGALFAACIHDVDHPGLTNQFLVNSSSELALMYNDESVLENHHLAVAFKLLQNQGCDIFCNMQKKQRQTLRKMVIDIVLSTDMSKHMSLLADLKTMVETKKVAGSGVLLLDNYTDRIQVLENLVHCADLSNPTKPLPLYKRWVALLMEEFFLQGDKERESGMDISPMCDRHNATIEKSQVGFIDYIVHPLWETWADLVHPDAQD-ILDTLEENRDYYQSM 432

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: si:dkey-219c10.4 (si:dkey-219c10.4 [Source:ZFIN;Acc:ZDB-GENE-081105-151])

HSP 1 Score: 390.193 bits (1001), Expect = 2.122e-127
Identity = 212/546 (38.83%), Postives = 326/546 (59.71%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVIS--CCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL--------QNKASNPT 1742
            ++ +IIY     + EQ E P  C   D++D+ R+ + A   DI+KL N     +      L  N P   Y +EV++  C  +L  S ++      L  ++ R+ ++E++I     +     P+ + E++ ++   +++ + + HLS                           +    + M +  H     + SP     ++ KT ++   V  ++  +   E+   VR+ LKT +F+ W + DAE++ L+++M+ +L   + FNI    L Q+L+ VY+ YN +PFHNF H FCV QM+Y +I L +LR   DS+++L ++ SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE+ + NI ++L  +Q+K++RE  IKCIL+TDM++H DI+ +F+ +LP  D  N   HR +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV+ PLF     +FP +E  I+ PV+  L+YYT++        QN+A N T
Sbjct:    3 MATKIIYFTVNGRPEQAEFPIDCPAQDVKDLFRAAAEAGPHDILKLYN-TKGNIINISPQLASNSPHSYYKLEVVAADCNSELLGSELAVALGFDLTSMEKRLQSLEKRIL----TEAAETPAIVYEMKRQVESFREKLESVEHLS---------------------------WLGLFKDMSEGTH-----KPSPFYHKRTLRKTREECEHVREKFLQMSSLEVSEEVRQYLKTPTFDNWQWEDAEIMVLLQVMYTDLDFISTFNIEPDVLQQFLYEVYRRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKIDSIDLLIMLTSAVCHDLDHTGYNNAYQINARTELALRYNDISPLENHHCAVAFEILEKTESNIFRNLPTEQYKRIREGIIKCILATDMSRHTDILNKFKAILPVFDFGN-KDHRDVLMMIMIKVSDISNEARPMDVAEPWLDCLLQEFFNQSDMEKLEGLPVTPFMDRDKVTKPSSQTGFIRFVLFPLFIELANLFPCLEQHIIDPVRKALDYYTEMEKALEREKQNRALNET 510

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde9a (phosphodiesterase 9A [Source:ZFIN;Acc:ZDB-GENE-130920-1])

HSP 1 Score: 318.931 bits (816), Expect = 5.570e-100
Identity = 150/314 (47.77%), Postives = 212/314 (67.52%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            S  K  + +   E LK   F++W +   E+++ ++ M+ +L L   FNI   TL +WL  ++ NY   PFHNF H FCV QM+Y+MI L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQI  +   NI      + FK++R+ +I  IL+TDM +H +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDREKVTK  +Q GFIKFV++P+FE   ++FP +E+++++P++   + Y +L+
Sbjct:  173 SYPKYHLSQDTVEALKQPLFDVWQWESNEMLSCLEHMYHDLGLVKDFNINPITLKRWLLCIHDNYRNNPFHNFRHCFCVTQMMYSMIYLCGLQEKFTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQPDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDY-NNEEHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKAEGLPVAPFMDREKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEVMVQPLRESRDKYEELK 485

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde9al (phosphodiesterase 9A like [Source:ZFIN;Acc:ZDB-GENE-130530-807])

HSP 1 Score: 315.464 bits (807), Expect = 1.163e-98
Identity = 148/314 (47.13%), Postives = 216/314 (68.79%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            S  K  + +   E LK  +F++W +   E+++ ++ M+ +L L   FNI   TL +WL  + +NY + PFHNF H FCV QM+Y MI+L NL+E     ++  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FK++R+  I  IL+TDM +H +I+  F++ +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP A FMDREKVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+
Sbjct:  183 SYPKYTLSQETIEALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYRSNPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHKVDHFDFTNE-EHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAAFMDREKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELK 495

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: FQ378016.1 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [Source:NCBI gene;Acc:571737])

HSP 1 Score: 310.071 bits (793), Expect = 3.772e-98
Identity = 143/300 (47.67%), Postives = 210/300 (70.00%), Query Frame = 3

Query:  822 LKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            LK  +F++W +   E+++ ++ M+ +L L   FN+   TL +WL ++ +NY   PFHNF H FCV QM+Y MI+L  L++     ++  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FK++R+  I  IL+TDM KH +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+
Sbjct:   74 LKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRDNPFHNFRHCFCVSQMMYGMIHLCGLQDRLTMTDMCILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMAKHGEILDSFKQKVDNFDCTNE-EHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELK 372

[Close]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: FQ378016.1 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [Source:NCBI gene;Acc:571737])

HSP 1 Score: 311.997 bits (798), Expect = 3.120e-97
Identity = 143/300 (47.67%), Postives = 210/300 (70.00%), Query Frame = 3

Query:  822 LKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            LK  +F++W +   E+++ ++ M+ +L L   FN+   TL +WL ++ +NY   PFHNF H FCV QM+Y MI+L  L++     ++  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FK++R+  I  IL+TDM KH +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+
Sbjct:  196 LKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRDNPFHNFRHCFCVSQMMYGMIHLCGLQDRLTMTDMCILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSMPECNIFANIEPESFKQIRQAIITLILATDMAKHGEILDSFKQKVDNFDCTNE-EHVKSLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELK 494

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: ENSXETT00000043255.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:65150883:65160642:1 gene:ENSXETG00000020480.1 transcript:ENSXETT00000043255.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 245.358 bits (625), Expect = 2.114e-75
Identity = 114/221 (51.58%), Postives = 161/221 (72.85%), Query Frame = 3

Query: 1056 REIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL 1718
            +E    +E+  LM SA+ HDLDHPG NN +QINA T LA RYND SPLENHHCA+AFQIL + + NI  ++T + FK++R+  I+ IL+TDM +H +I+  F+ +LP  D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP  PFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E++++ P++   ++Y +L
Sbjct:   14 KEKMSLIELGVLMTSAVCHDLDHPGYNNTYQINAHTELAIRYNDMSPLENHHCAVAFQILAQPENNIFANITPELFKQIRQSIIRLILATDMARHGEILESFKKVLPNFDFSNE-DHVKTLQMVLIKCCDISNEVRPTKVAEPWVDCLLEEYFMQSDREKSEGLPVTPFMDRDKVTKPKAQIGFIKFVLIPMFESVMKLFPHIEEVMVLPLREARDHYEEL 233

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: c16orf72 (chromosome 16 open reading frame 72 [Source:Xenbase;Acc:XB-GENE-957508])

HSP 1 Score: 245.743 bits (626), Expect = 2.829e-74
Identity = 124/301 (41.20%), Postives = 190/301 (63.12%), Query Frame = 3

Query:  789 KSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVK 1691
            +++I    RE LK  +FN+      ++++L++ MF  L L   F +   TL  +L SV ++Y   PFHNF H F V QMLY +I+   L+E     + L +M +AL HDLDHPGL+N++Q+NA+T LA+RYN  SPLENHH A+  +IL ++K N+L ++  +Q   +++  ++ IL+TDM  H  I+   ++ +  L   N   H   L   +IKLCDISNEARP   +E W + L+EE+F QSD EK +GLP  P+MDR++V K+++Q  FI F+++PL E   +  P + D +L+P++
Sbjct:   24 RTQIPEGTREALKRPTFNVLGMERPQMLSLLEHMFYQLDLVATFKMEPETLRCFLSSVQEHYQENPFHNFHHGFSVAQMLYCVISQCQLQERLLPSDTLAMMVAALCHDLDHPGLSNSYQVNAQTDLAKRYNYNSPLENHHWAVTLRILSQEKSNLLVNVAPEQLPHIQQEIMELILATDMVHHGKILQSLQH-IETLSFSN-REHVTALKKTLIKLCDISNEARPADQAEVWADSLMEEYFLQSDREKAEGLPVTPYMDRDRVRKADAQSSFITFLLLPLCEALCQHLPQLSDSLLQPLR 322

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: c16orf72 (chromosome 16 open reading frame 72 [Source:Xenbase;Acc:XB-GENE-957508])

HSP 1 Score: 204.142 bits (518), Expect = 7.883e-59
Identity = 111/313 (35.46%), Postives = 179/313 (57.19%), Query Frame = 3

Query:  789 KSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNK 1727
            +++I    RE LK  +FN+      ++++L++ MF  L L   F +   TL  +L SV ++Y   PFHNF H F V QMLY +I+   L+E     + L +M +AL HDLDHPGL+N++Q+NA+T LA+RYN  SPLENHH A+  +IL ++K N+L ++  +Q   +++  ++ IL+TDM  H  I+   ++ +  L   N      +        C   +    P   +PW+   +   F QSD EK +GLP  P+MDR++V K+++Q  FI F+++PL E   +  P + D +L+P++     Y +  +K
Sbjct:   21 RTQIPEGTREALKRPTFNVLGMERPQMLSLLEHMFYQLDLVATFKMEPETLRCFLSSVQEHYQENPFHNFHHGFSVAQMLYCVISQCQLQERLLPSDTLAMMVAALCHDLDHPGLSNSYQVNAQTDLAKRYNYNSPLENHHWAVTLRILSQEKSNLLVNVAPEQLPHIQQEIMELILATDMVHHGKILQSLQH-IETLSFSNREHVTAVRTAPRYPKCPSVSYTHLPISPKPWVPVNV-FLFIQSDREKAEGLPVTPYMDRDRVRKADAQSSFITFLLLPLCEALCQHLPQLSDSLLQPLRAAKLRYQQQMDK 331

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 187.193 bits (474), Expect = 9.400e-50
Identity = 101/314 (32.17%), Postives = 182/314 (57.96%), Query Frame = 3

Query:  837 FNMWSFSDAELINLV-KLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNT-VPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLP-------KLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYYTKLQNKASNPTAD 1748
            F +  FS    + +V   +F   ++   F IP+ TL  +L ++  +Y+  V +HN  HA  V Q  + +++   L  +F  LEIL  +F++  HD+DHPG++N F IN  + LA  YND S LENHH A+ F++L+E+  +I ++LT KQ + LR++ I  +L+TDM+KH +++ + + ++         + L+++ S RI ++  ++   D+SN  +P  +   W + ++EEFF+Q D E+ +G+  +P  D+   +   SQ GFI +++ PL+E + + V P  +D IL  +++  E+Y     ++ +P  D
Sbjct:  279 FKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD-ILDTLEDNREWYQSTIPQSPSPAPD 591

[Close]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE4D (phosphodiesterase 4D [Source:NCBI gene;Acc:100496479])

HSP 1 Score: 186.422 bits (472), Expect = 1.054e-49
Identity = 101/314 (32.17%), Postives = 182/314 (57.96%), Query Frame = 3

Query:  837 FNMWSFSDAELINLV-KLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNT-VPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLP-------KLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYYTKLQNKASNPTAD 1748
            F +  FS    + +V   +F   ++   F IP+ TL  +L ++  +Y+  V +HN  HA  V Q  + +++   L  +F  LEIL  +F++  HD+DHPG++N F IN  + LA  YND S LENHH A+ F++L+E+  +I ++LT KQ + LR++ I  +L+TDM+KH +++ + + ++         + L+++ S RI ++  ++   D+SN  +P  +   W + ++EEFF+Q D E+ +G+  +P  D+   +   SQ GFI +++ PL+E + + V P  +D IL  +++  E+Y     ++ +P  D
Sbjct:  229 FKVAEFSGNRPLTVVMHTIFQEREMLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVAQSTHVLLSSPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQLLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLPLYRHWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQD-ILDTLEDNREWYQSTIPQSPSPAPD 541

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde9a (phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:1277179])

HSP 1 Score: 315.079 bits (806), Expect = 2.739e-100
Identity = 148/302 (49.01%), Postives = 212/302 (70.20%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:   36 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 336

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde9a (phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:1277179])

HSP 1 Score: 315.464 bits (807), Expect = 2.826e-100
Identity = 148/302 (49.01%), Postives = 212/302 (70.20%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:   46 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 346

[Close]

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:   46 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 346

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde9a (phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:1277179])

HSP 1 Score: 317.005 bits (811), Expect = 1.724e-99
Identity = 148/302 (49.01%), Postives = 212/302 (70.20%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:  152 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 452

[Close]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde9a (phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:1277179])

HSP 1 Score: 317.39 bits (812), Expect = 1.911e-99
Identity = 148/302 (49.01%), Postives = 212/302 (70.20%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:  167 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 467

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|H2QL32|PDE9A_PANTR (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Pan troglodytes OX=9598 GN=PDE9A PE=1 SV=1)

HSP 1 Score: 322.783 bits (826), Expect = 1.228e-99
Identity = 150/302 (49.67%), Postives = 215/302 (71.19%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  254 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQENFSQMDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 554

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|O76083|PDE9A_HUMAN (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Homo sapiens OX=9606 GN=PDE9A PE=1 SV=1)

HSP 1 Score: 321.627 bits (823), Expect = 3.042e-99
Identity = 150/302 (49.67%), Postives = 214/302 (70.86%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WLF V+ NY   PFHNF H FCV QM+Y+M+ L +L+E F   +IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL E + NI  ++    FK++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+++L+P+    + Y +L+
Sbjct:  254 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELK 554

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q8QZV1|PDE9A_RAT (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Rattus norvegicus OX=10116 GN=Pde9a PE=1 SV=1)

HSP 1 Score: 317.775 bits (813), Expect = 1.785e-98
Identity = 148/302 (49.01%), Postives = 213/302 (70.53%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY + PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:  193 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRSNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPIVEETMLRPLWESREHYEELK 493

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|O70628|PDE9A_MOUSE (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Mus musculus OX=10090 GN=Pde9a PE=1 SV=1)

HSP 1 Score: 317.775 bits (813), Expect = 2.252e-98
Identity = 148/302 (49.01%), Postives = 212/302 (70.20%), Query Frame = 3

Query:  816 ENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            E L+  +F++W +   E+++ ++ M+ +L L   F+I   TL +WL  V+ NY   PFHNF H FCV QM+Y+M+ L  L+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI   +  + F+++R+  I  IL+TDM +HA+I+  F+  +   D  N+  H  +L +++IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK+ +Q GFIKFV++P+FE   ++FP VE+ +L+P+    E+Y +L+
Sbjct:  193 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE-EHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPVVEETMLRPLWESREHYEELK 493

[Close]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9I7S6|PDE9A_DROME (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Drosophila melanogaster OX=7227 GN=Pde9 PE=2 SV=2)

HSP 1 Score: 332.798 bits (852), Expect = 5.379e-97
Identity = 163/344 (47.38%), Postives = 231/344 (67.15%), Query Frame = 3

Query:  810 VRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGT 1841
            VR  L+  +F+ + +SDA++I+L++ MF+ L     F+IP+ TL +WL+ VY++YN VPFHNF H FCV QM+YA+   ANL      LE L L+ S + HDLDHPG NN +QINART LA RYND SPLENHHC++AF++LE  + NI K+ +   F  +RE  I+CIL+TDM +H +I+T+F  + P  D  N  +H  +L +++IK+ DISNEARP  ++EPWL+ LL+EFF QS  EK +GLP  PFMD +KV+K  SQ  FI  V++PLFE  GE+ P + +LI+ PV+  LEYY +L N A   T  +++     SN +    +++G+I S  + + T
Sbjct:  680 VRAALRLPAFDSYEWSDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVYKHYNEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEILTQFMEITPIFDYSN-RAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEGLPVTPFMDPDKVSKPGSQVRFIGLVLLPLFEALGELVPELTELIIIPVRIALEYYRRL-NDAQTKTRKSVAD----SNTSATSDSNSGTIDSNAAMVST 1017

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BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A401SLV9 (Phosphodiesterase OS=Chiloscyllium punctatum OX=137246 GN=chiPu_0009826 PE=3 SV=1)

HSP 1 Score: 401.749 bits (1031), Expect = 7.247e-128
Identity = 221/558 (39.61%), Postives = 331/558 (59.32%), Query Frame = 3

Query:  141 SNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVIS--CCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLS-----RQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL--------QNKASNPTADAISGPL 1766
            + +IIY     + EQ E P  C   D+++V R+ + A   DI+KL N     +      LE N     Y +EV++  C      S ++      L  ++ R+  +E+KI  L  S     PS + E+ +R+   +++ + + HLS     ++LS                                     N  ++ SP     S+ KT ++   V   Y  +   E+   VR+ LKT +F+ W + DAE++ L++LM+I+L     FNI +  L Q+LF VY++YN +PFHNF H FCV QM+Y +I L +L+   D ++ILT++ SA+ HDLDHPG NNA+QINART LA RYND SPLENHHC++AF ILE+ + NI ++LT +QFK++RE  IKC+L+TDMT+H +I+ +FR+++   D  N+ +H+ +L +++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP +PFMDR+KVTK +SQ GFI+FV++PLF     +FPS+E  I+ PV+  L+YYT++        QN+      D +  PL
Sbjct:    3 TTKIIYFSVDGRPEQAEFPSDCPAQDVKEVFRAAAEAGPYDILKLYN-TKGNIINISPKLESNTRQTQYKLEVVAADCKTYSLGSELATALGFDLLAMEKRLQTLEKKI--LVAS--TDMPSIMYEMRNRVESFREKLESVEHLSWLGLFKELS-------------------------------------NGTNKPSPFYHKRSLRKTKEECQQVMENYLQMSSLEVTEEVRQYLKTPTFDNWQWEDAEIMVLLQLMYIDLDFMNKFNIEMEVLQQFLFEVYRHYNNIPFHNFKHCFCVTQMMYGLIWLTDLQNKMDDIDILTMLTSAICHDLDHPGYNNAYQINARTELALRYNDISPLENHHCSVAFNILEKSENNIFRNLTTEQFKRIREGMIKCVLATDMTRHNEILNQFRSIVSVFDF-NNKNHKDILTMIIIKVSDISNEARPLDVAEPWLDCLLQEFFNQSDMEKLEGLPVSPFMDRDKVTKPSSQTGFIRFVLLPLFIELANLFPSLEQHIIDPVRKALDYYTEMEKALEKEKQNRTGGSQCDKVVKPL 517

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3JYR8 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106177225 PE=3 SV=1)

HSP 1 Score: 400.593 bits (1028), Expect = 1.148e-127
Identity = 226/531 (42.56%), Postives = 330/531 (62.15%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSR-QLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQN 1724
            ++ ++IY   A K EQ E       DD+ D+ R+ + A   DI+KL N     L    S LE N P   Y ++V++   Q   S I++    ++  ++ R+ N+E+KI  L D      PS + ++  ++ + ++R + + HLS   LS++            IS + S+ P++    + +Q    ND         +  I +  K++ TV          ++   VR+ LK  +F+ W + DAE++ L++ M+I+L   T FNI L+ L  WLF VY++YN VPFHNF H F V QM+Y M  L +L    D LE+L L+ SA+ HDL HPG NNA+QINART LA RYND SPLENHHC++AF+ILE+   NI +++    FK++RE  IKCIL+TDM KH++IV  F++L+P  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL EFF QSD+EKL+GLP APFMDREKVTKS+SQ GFIK+V++PLFE  GE+FP +E+ I++PV+  L+YYT + +
Sbjct:    1 MATKVIYFTVAGKEEQAEFRSTDNQDDVRDIFRAAAEAGPHDILKLYN-TKGNLINISSKLEQNTPESRYKLDVVAA--QCTDSSIAEQLGFNIHNVESRLQNLEKKI--LVDK--GDTPSLVYDIRHKVEEFRERLEHVDHLSWLGLSKD------------ISVKTSLKPFWDKNNSPKQ----ND-------AHYKRIFEKFKKMSTV----------QVTDEVRDYLKKPTFDNWQWDDAEMLILLQQMYIDLGFLTKFNIELSVLQHWLFEVYRHYNPVPFHNFKHCFMVAQMMYGMTWLIDLSSYIDDLEVLVLITSAICHDLGHPGYNNAYQINARTELALRYNDISPLENHHCSVAFEILEKNNANIFRNVPVDTFKRIREGMIKCILATDMAKHSEIVNNFKSLIPNFDFKN-KEHKSLLMMILIKVADISNEARPLEVAEPWLDCLLTEFFTQSDVEKLEGLPVAPFMDREKVTKSSSQMGFIKYVLLPLFEALGELFPCIEEQIIEPVRIGLKYYTDMHS 490

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3JZ65 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106177225 PE=3 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 1.916e-126
Identity = 226/533 (42.40%), Postives = 328/533 (61.54%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVIS--CCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSR-QLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQN 1724
            ++ ++IY   A K EQ E       DD+ D+ R+ + A   DI+KL N     L    S LE N P   Y ++V++  C  QL           ++  ++ R+ N+E+KI  L D      PS + ++  ++ + ++R + + HLS   LS+            +IS + S+ P++    + +Q    ND         +  I +  K++ TV          ++   VR+ LK  +F+ W + DAE++ L++ M+I+L   T FNI L+ L  WLF VY++YN VPFHNF H F V QM+Y M  L +L    D LE+L L+ SA+ HDL HPG NNA+QINART LA RYND SPLENHHC++AF+ILE+   NI +++    FK++RE  IKCIL+TDM KH++IV  F++L+P  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL EFF QSD+EKL+GLP APFMDREKVTKS+SQ GFIK+V++PLFE  GE+FP +E+ I++PV+  L+YYT + +
Sbjct:    1 MATKVIYFTVAGKEEQAEFRSTDNQDDVRDIFRAAAEAGPHDILKLYN-TKGNLINISSKLEQNTPESRYKLDVVAAQCTEQL---------GFNIHNVESRLQNLEKKI--LVDK--GDTPSLVYDIRHKVEEFRERLEHVDHLSWLGLSK------------DISVKTSLKPFWDKNNSPKQ----ND-------AHYKRIFEKFKKMSTV----------QVTDEVRDYLKKPTFDNWQWDDAEMLILLQQMYIDLGFLTKFNIELSVLQHWLFEVYRHYNPVPFHNFKHCFMVAQMMYGMTWLIDLSSYIDDLEVLVLITSAICHDLGHPGYNNAYQINARTELALRYNDISPLENHHCSVAFEILEKNNANIFRNVPVDTFKRIREGMIKCILATDMAKHSEIVNNFKSLIPNFDFKN-KEHKSLLMMILIKVADISNEARPLEVAEPWLDCLLTEFFTQSDVEKLEGLPVAPFMDREKVTKSSSQMGFIKYVLLPLFEALGELFPCIEEQIIEPVRIGLKYYTDMHS 485

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: W5M2C2 (Phosphodiesterase OS=Lepisosteus oculatus OX=7918 PE=3 SV=1)

HSP 1 Score: 397.127 bits (1019), Expect = 4.047e-126
Identity = 225/585 (38.46%), Postives = 349/585 (59.66%), Query Frame = 3

Query:  132 LYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVISC-CPQLFTSLISQGARRS------LQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTK----LQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISR 1850
            L ++ +IIY     + EQ E    C   D++D+ R+ + A   DI+KL N     +      LEPN P   Y +EV++  C     S+   GA  +      L  ++ R+ ++E+KI  L ++     PS ++E++S++   +++ + + HLS                           +    + + +  H     + SP     ++ KT ++   V   +  +   E+   V++ LKT +F+ W + DAE++ L+++M+ +L   T FNI L  L ++L+ VY+ YN +PFHNF H FCV QM+Y +I L +LR  FD +++LT+M SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE+ + NI ++L+ +Q+K++RE  IKCIL+TDM +H +I+ +F+++LP  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV++PLF     +FPS+E  I+ PV+  L+YYT+    L+ +  N       G + V+N    R+ +  S P   ++ G +SR
Sbjct:    1 LQMAAKIIYFTVNGRAEQAEFREDCPAQDVKDLFRAAAEAGPYDILKLYN-TKGNIINISPGLEPNTPQSCYKLEVVAADC----NSVNVTGADLATVLGFDLSSMEKRLQSLEKKI--LVEA--GETPSVVLEMKSQVESFREKLESVEHLS---------------------------WLGLFKELSEGTH-----KPSPFYHKRALRKTREECERVRETFLQMSSLEVTEEVKQYLKTPTFDNWQWEDAEIMVLLRVMYTDLDFMTKFNIELEVLQEFLYEVYRRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKFDDIDLLTMMTSAVCHDLDHTGYNNAYQINARTELALRYNDISPLENHHCAVAFEILEKTENNIFRNLSTEQYKRIREGMIKCILATDMARHNEILNKFKSILPAFDFTN-KDHKDVLMMIMIKVSDISNEARPMDVAEPWLDCLLQEFFNQSDMEKLEGLPVTPFMDRDKVTKPSSQTGFIRFVLLPLFIELANLFPSLEQHIIDPVRKALDYYTEMEKALEKEKQNRAQGDQPGKVQVANTDRPREPAAPSDPKTPAN-GNLSR 542

[Close]

BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3JYL5 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106177225 PE=3 SV=1)

HSP 1 Score: 396.356 bits (1017), Expect = 4.710e-126
Identity = 224/534 (41.95%), Postives = 325/534 (60.86%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSF---HDSYPSHIVELESRIIKLQDRFQKM-HLSR-QLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQN 1724
            ++ ++IY   A K EQ E       DD+ D+ R+ + A   DI+KL N     L    S LE N P   Y ++V++             A+ + ++L   I NVE ++Q L           PS + ++  ++ + ++R + + HLS   LS++            IS + S+ P++    + +Q    ND         +  I +  K++ TV          ++   VR+ LK  +F+ W + DAE++ L++ M+I+L   T FNI L+ L  WLF VY++YN VPFHNF H F V QM+Y M  L +L    D LE+L L+ SA+ HDL HPG NNA+QINART LA RYND SPLENHHC++AF+ILE+   NI +++    FK++RE  IKCIL+TDM KH++IV  F++L+P  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL EFF QSD+EKL+GLP APFMDREKVTKS+SQ GFIK+V++PLFE  GE+FP +E+ I++PV+  L+YYT + +
Sbjct:    1 MATKVIYFTVAGKEEQAEFRSTDNQDDVRDIFRAAAEAGPHDILKLYN-TKGNLINISSKLEQNTPESRYKLDVVA-------------AQCTAEQLGFNIHNVESRLQNLEKKILVDKGDTPSLVYDIRHKVEEFRERLEHVDHLSWLGLSKD------------ISVKTSLKPFWDKNNSPKQ----ND-------AHYKRIFEKFKKMSTV----------QVTDEVRDYLKKPTFDNWQWDDAEMLILLQQMYIDLGFLTKFNIELSVLQHWLFEVYRHYNPVPFHNFKHCFMVAQMMYGMTWLIDLSSYIDDLEVLVLITSAICHDLGHPGYNNAYQINARTELALRYNDISPLENHHCSVAFEILEKNNANIFRNVPVDTFKRIREGMIKCILATDMAKHSEIVNNFKSLIPNFDFKN-KEHKSLLMMILIKVADISNEARPLEVAEPWLDCLLTEFFTQSDVEKLEGLPVAPFMDREKVTKSSSQMGFIKYVLLPLFEALGELFPCIEEQIIEPVRIGLKYYTDMHS 486

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: si:dkey-219c10.4 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [Source:NCBI gene;Acc:103030131])

HSP 1 Score: 385.571 bits (989), Expect = 2.192e-125
Identity = 208/531 (39.17%), Postives = 322/531 (60.64%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVIS--CCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            + ++IIY     + EQ E P  C   D++D+ RS + A   DI+KL N     +      L PN P   Y +EV++  C  +   + ++      L  ++ R+ ++E+KI     +     P+ + E++ ++   +++ + + HLS                           +    + + +  H     + SP     ++ KT ++   V  ++  +   E+   VR+ LKT +F+ W + DAE++ L+++M+ +L   + FNI L  L Q+L+ VY+ YN +PFHNF H FCV QM+Y +I L +LR   DS+++L ++ SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE+ + NI ++LT +Q+K++RE  IKCIL+TDM++H DI+ +F+ +L   D  N   HR +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV+ PLF     +FP +E  I+ PV+  L+YYT+++
Sbjct:    1 MESKIIYFTVNGRPEQAEFPVDCPAQDVKDLFRSAAEAGPHDILKLYN-PKGNIINISPQLTPNSPHSCYKLEVVAADCNSEPLGTELAVALGFDLSSMEKRLQSLEKKIL----TEASETPAIVYEMKRQVESFREKLESVEHLS---------------------------WLGLFKELSERPH-----KPSPFYHKRTLRKTREECEHVREKFLQMSTLEVSEEVRQYLKTPTFDNWQWEDAEIMVLLQVMYTDLDFISTFNIELDVLQQFLYEVYKRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKIDSVDLLIMLTSAVCHDLDHTGYNNAYQINARTELALRYNDISPLENHHCAVAFEILEKNESNIFRNLTTEQYKRIREGIIKCILATDMSRHTDILNKFKAILSTFDFDN-KDHRDVLMMIMIKVSDISNEARPMDVAEPWLDCLLQEFFNQSDMEKLEGLPVTPFMDRDKVTKPSSQTGFIRFVLFPLFIELANLFPCLEQHIIDPVRKALDYYTEME 493

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: si:dkey-219c10.4 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [Source:NCBI gene;Acc:103030131])

HSP 1 Score: 370.163 bits (949), Expect = 1.591e-119
Identity = 171/340 (50.29%), Postives = 246/340 (72.35%), Query Frame = 3

Query:  702 QSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            + SP     ++ KT ++   V  ++  +   E+   VR+ LKT +F+ W + DAE++ L+++M+ +L   + FNI L  L Q+L+ VY+ YN +PFHNF H FCV QM+Y +I L +LR   DS+++L ++ SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE+ + NI ++LT +Q+K++RE  IKCIL+TDM++H DI+ +F+ +L   D  N   HR +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV+ PLF     +FP +E  I+ PV+  L+YYT+++
Sbjct:  127 KPSPFYHKRTLRKTREECEHVREKFLQMSTLEVSEEVRQYLKTPTFDNWQWEDAEIMVLLQVMYTDLDFISTFNIELDVLQQFLYEVYKRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKIDSVDLLIMLTSAVCHDLDHTGYNNAYQINARTELALRYNDISPLENHHCAVAFEILEKNESNIFRNLTTEQYKRIREGIIKCILATDMSRHTDILNKFKAILSTFDFDN-KDHRDVLMMIMIKVSDISNEARPMDVAEPWLDCLLQEFFNQSDMEKLEGLPVTPFMDRDKVTKPSSQTGFIRFVLFPLFIELANLFPCLEQHIIDPVRKALDYYTEME 465

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde9a (phosphodiesterase 9A [Source:NCBI gene;Acc:103028423])

HSP 1 Score: 322.783 bits (826), Expect = 1.206e-101
Identity = 153/321 (47.66%), Postives = 217/321 (67.60%), Query Frame = 3

Query:  822 LKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ--NKASNPTADAISGPLTVSN 1778
            L+  +F++W +   E+++ ++ M+ +L L   FNI   TL +WL  ++ NY   PFHNF H FCV QM+Y+MI L NL+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQI  +   NI  +   + FK++R+ +I  IL+TDM +H +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDREKVTK  +Q GFIKFV++P+FE   ++FP +ED++++P++   + Y +L+  + A N      S  LT+  
Sbjct:  188 LRKPAFDVWLWESNEMLSCLEHMYHDLGLVRDFNINPITLKRWLLCIHDNYRNNPFHNFRHCFCVTQMMYSMIYLCNLQEKFSQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQADCNIFSNFDAEAFKQIRQGTITLILATDMARHGEILDSFKQKVDNFDFTNE-EHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKAEGLPVAPFMDREKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEDVMVQPLRESRDRYEELKQIDDAMNEVQKKKSENLTMGG 507

[Close]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde9a (phosphodiesterase 9A [Source:NCBI gene;Acc:103028423])

HSP 1 Score: 322.398 bits (825), Expect = 1.804e-101
Identity = 155/335 (46.27%), Postives = 221/335 (65.97%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ--NKASNPTADAISGPLTVSN 1778
            S  K  + +   + L+   F++W +   E+++ ++ M+ +L L   FNI   TL +WL  ++ NY   PFHNF H FCV QM+Y+MI L NL+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQI  +   NI  +   + FK++R+ +I  IL+TDM +H +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDREKVTK  +Q GFIKFV++P+FE   ++FP +ED++++P++   + Y +L+  + A N      S  LT+  
Sbjct:  174 SYPKYHLSKETIDALRQPVFDVWQWEPNEMLSCLEHMYHDLGLVRDFNINPITLKRWLLCIHDNYRNNPFHNFRHCFCVTQMMYSMIYLCNLQEKFSQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQADCNIFSNFDAEAFKQIRQGTITLILATDMARHGEILDSFKQKVDNFDFTNE-EHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKAEGLPVAPFMDREKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEDVMVQPLRESRDRYEELKQIDDAMNEVQKKKSENLTMGG 507

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BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde9a (phosphodiesterase 9A [Source:NCBI gene;Acc:103028423])

HSP 1 Score: 320.472 bits (820), Expect = 8.377e-101
Identity = 150/314 (47.77%), Postives = 214/314 (68.15%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            S  K  + +   + L+   F++W +   E+++ ++ M+ +L L   FNI   TL +WL  ++ NY   PFHNF H FCV QM+Y+MI L NL+E F  ++IL LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQI  +   NI  +   + FK++R+ +I  IL+TDM +H +I+  F+  +   D  N+  H   L +V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDREKVTK  +Q GFIKFV++P+FE   ++FP +ED++++P++   + Y +L+
Sbjct:  150 SYPKYHLSKETIDALRQPVFDVWQWEPNEMLSCLEHMYHDLGLVRDFNINPITLKRWLLCIHDNYRNNPFHNFRHCFCVTQMMYSMIYLCNLQEKFSQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQADCNIFSNFDAEAFKQIRQGTITLILATDMARHGEILDSFKQKVDNFDFTNE-EHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKAEGLPVAPFMDREKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEDVMVQPLRESRDRYEELK 462

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: si:dkey-219c10.4 (si:dkey-219c10.4 [Source:ZFIN;Acc:ZDB-GENE-081105-151])

HSP 1 Score: 221.09 bits (562), Expect = 2.825e-68
Identity = 101/175 (57.71%), Postives = 138/175 (78.86%), Query Frame = 3

Query: 1143 FQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVE 1667
            FQINART LA RYND SPLENHHCA+AF++LEE + NI ++LT +Q+K++RE  IKCIL+TDM +H DI+  F  +LP  D  N   H  +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP +PFMDR+KV++S+SQ  FI+ V++PLF     +FP+++
Sbjct:    1 FQINARTELALRYNDISPLENHHCAVAFELLEEHESNIFRNLTKEQYKRVREGMIKCILATDMGRHNDILASFNTILPTFDFRN-REHTDVLMMIMIKVSDISNEARPMQVAEPWLDCLLQEFFSQSDVEKLEGLPVSPFMDRDKVSRSSSQVNFIRHVLLPLFVALATLFPALQ 174

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde9al (phosphodiesterase 9A like [Source:ZFIN;Acc:ZDB-GENE-130530-807])

HSP 1 Score: 221.476 bits (563), Expect = 5.120e-66
Identity = 123/311 (39.55%), Postives = 183/311 (58.84%), Query Frame = 3

Query:  822 LKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQ-----------NYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFF-QQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL 1718
            LK  +F++W +   E+++ ++ MF +L L + FNI   TL  WL  V             ++ +  F  F+ A C +  ++  IN         S+  +    + + H +D       +Q+NART LA RYND SPLENHH A+AF IL   + NIL  +T   F  +R+  I+ ILSTDM +H +I+  FR  L   D  N   H  +L +++IK CDISNE RP  +SEPWL+CLLEE+F QQSD EK +GLP+A FMDR+ VTK ++Q GF+ FV++PL E   ++FP +E+ ++ P++   ++Y +L
Sbjct:   27 LKQPTFDVWQWEHNEMLSCLEHMFHDLGLVSEFNINPITLKPWLSVVMDRGIKTTNTLLLSFGSTEF-RFSRAQCGMMHMFQSIN--------GSVMPIKTEKTNIFHSVDCVAYMPRYQVNARTELAVRYNDVSPLENHHAAVAFHILSTPETNILSGVTHHAFTHIRQGVIELILSTDMARHGEILASFREYLKDFDFGN-PEHMKVLKMMLIKCCDISNEVRPMEVSEPWLDCLLEEYFMQQSDREKQEGLPFAAFMDRDTVTKPSAQIGFLSFVLIPLLEAVSQLFPQMEETMVHPLRESRDHYQEL 327

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777])

HSP 1 Score: 157.147 bits (396), Expect = 9.624e-41
Identity = 85/294 (28.91%), Postives = 154/294 (52.38%), Query Frame = 3

Query:  849 SFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQ-SPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNK 1727
            S  + + I  +  M  ++     + + L TL +W   V + Y   P+HN+ HA+ V    Y +    +L +    +EI  L  S L HDLDH G NN+FQ+++++ LA  Y+ + S +E HH A A  I+     NIL++L+ K+++++ ++    IL+TD+  H  I  + R +       ++     +L+ +++  CD+S++ +    +    E + +EFF Q DLEK  G   +  MDREK      Q  F++ + MPLF+L  ++ P   +L  +   N+ E++ ++ +K
Sbjct:  293 SLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIADAGYNPDNGHQHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPSEMMDREKAYIPELQISFMEHIAMPLFKLLKDMLPGAAELYERVAANK-EHWMRVSHK 585

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2])

HSP 1 Score: 154.451 bits (389), Expect = 3.336e-40
Identity = 92/335 (27.46%), Postives = 171/335 (51.04%), Query Frame = 3

Query:  834 SFNMWSFSDAELINLVKLMFINL----QLTTAFNIPLTTLDQWLFSVYQNY--NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPS 1820
            SF+++  ++A   + +K +   L    +L + + IP+  L  ++ ++   Y  +  P+HN  HA  V Q ++ ++  + L      LE L ++F+A  HDL+H G  N F I  R+ +A  YND++ LENHH + A++++++   NI  +L+   +++LR + ++ +L+TDM+ H   +   ++ L + + ++ S      M +++   DIS+  +   + + W E L+EEFF+Q D E   GLP++P  DR     + SQ GF+ F++ P F     V   + + ++ P+  +         +A  P         TV      R  S GS+ S
Sbjct:  154 SFDVFVLNEASGEHALKFVMHELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPESIDKSK----AMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEPTF----SVLTDMAEKVVVPLAEE-------AARAGTPGVPRRGSAATVEWHRGKRAASDGSVTS 473

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BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776])

HSP 1 Score: 147.517 bits (371), Expect = 2.035e-38
Identity = 88/304 (28.95%), Postives = 164/304 (53.95%), Query Frame = 3

Query:  807 SVRENLKTLSFNMWSFSDAELINLVKL----MFINLQLTTAFNIPLTTLDQWLFSVYQNY--NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEE-KKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQ 1697
            SV + +   SF++++  +A   + +K     +F    L   F IP++++  ++ ++   Y  +  P+HN  HA  V Q ++ ++         + LEIL+++F+A  HD +H G  N F I  R+  A  YND+S LENHH + A+++++E ++ NIL +L+   +++LR + ++ +L+TDM+ H   +   +NLL + + V         M +++   DIS+ A+  ++   W   L+EEFF+Q D E   GL ++P  DR       SQ GFI +++ P F     V   + + ++ P+ ++
Sbjct:  136 SVLKEVDKWSFDVFALHEASGEHALKFIVYELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQLKSIKNLLQQPEGVEKPK----AMSLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAELGLSFSPLCDRNATMVPQSQIGFIDYIVEPTF----TVLTDLSEFVVAPLIDE 431

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BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887])

HSP 1 Score: 72.4034 bits (176), Expect = 1.120e-13
Identity = 58/187 (31.02%), Postives = 92/187 (49.20%), Query Frame = 3

Query:  954 FSVYQNYNTV-PFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEF 1511
            F++  +Y+ V  FHNF HA  V+Q  + +     L++  + ++ L L  +A+ HD+ HPG NN    N  + +AQ + + S LEN H  +  Q+L E    +L  ++ K+F  + E     IL+TDM  H+       +  P          +I L+ ++IK  DISN  R   IS  W   +  EF
Sbjct:  252 FTLESSYHQVNKFHNFRHAIDVMQATWRLCTYL-LKD--NPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS-ISKKKFDFISE----AILATDMALHSQYEDRLMHENPM--------KQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVS5])

HSP 1 Score: 362.073 bits (928), Expect = 3.168e-117
Identity = 207/530 (39.06%), Postives = 311/530 (58.68%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVI--SCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIV-ELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL 1718
            +++++IY     K EQ E       DD++++ RS + A   DI+KL N     +      L  N P   Y +EV+  SC       L   G   SL++L+ RI+++E++I        +  P  +V +++ ++   +D+ +                        S  C    +    + M         S ++P    S + K+ ++  +V+I+Y++L + E                    +AE++ L++ M+I+L L   F I  + L  +LF VY++YN  PFHNF HAFCV QM+Y +I L  +       ++L ++ SAL HDLDHPG NNA+QINART LA RYND SPLENHHCA+AF I+++ K NIL++++ + FKK+RE  IKCILSTDM +H+DI+ +F+ LL      +D +H+ MLM ++IK+ D+SNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP APFMDR+KVTK ++Q GFIKFV++PLFE  GE+FP +ED I+ PV+  L+YY  +
Sbjct:    1 MTSKVIYFTVGGKEEQAEFSSDIPADDVKELFRSAAEAGAYDILKLYN-TKGSIVNISPKLSENSPECRYKLEVVAASCSA---CGLCEPGNGCSLEKLEQRIESLEKQI-----IVENGEPPPVVKDIKLKVDSFRDKLE------------------------SVEC--LSWLGLFKEMT--------SGTTPRPKPSLMRKSSEEFESVFIRYRNLSQWE--------------------EAEMLYLLQQMYIDLGLLDEFKIERSKLQHFLFEVYRHYNPTPFHNFRHAFCVTQMMYGLIWLTEIFNKITKQDLLIMLTSALCHDLDHPGYNNAYQINARTELALRYNDISPLENHHCAVAFDIMKQDKSNILQNVSAETFKKIREGMIKCILSTDMARHSDILNKFKELLKSGFKFDDEAHKSMLMQIMIKVSDVSNEARPMDVAEPWLDCLLQEFFIQSDVEKLEGLPVAPFMDRDKVTKPSAQIGFIKFVLVPLFEALGELFPILEDHIVSPVRKALDYYVGM 467

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO46133 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM4])

HSP 1 Score: 165.236 bits (417), Expect = 9.339e-44
Identity = 98/317 (30.91%), Postives = 173/317 (54.57%), Query Frame = 3

Query:  807 SVRENLKTLSFNMWSFSDAELIN-LVKLMFINLQ---LTTAFNIPLTTLDQWLFSVYQNY-NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSS---------HRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEK-LKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYY 1709
            ++ EN+    F+ ++  +A   + ++ + +  LQ   L   F I  TT   ++  V  +Y   VPFHN  HA  V Q  + +++      +F  LEIL+ + ++  HD+DHPG+NN F +   + +A  YND+S LENHH A+AFQ+L+ +  +I ++L+ ++ +  R + I+ +L+TD  KH  ++   + ++    +    S          R+ ++  ++   D+SN  +P  I   W++ L+EEFF+Q D E+ + G+  +P MDR   +   SQ  FI FV  PL+E +GE V P  +DL L  +++  ++Y
Sbjct:  204 TILENVNKWDFDAFALGEATNGHPMLAVSYTILQARDLLKIFKIKPTTFINYMTLVENHYLKDVPFHNCIHAADVTQTAHVLLSAQAFDNVFTDLEILSAIIASAVHDVDHPGVNNHFLVATNSEMALMYNDESVLENHHLAVAFQLLQHEDCDIFENLSKQERQTARRMIIEMVLATDNAKHMSLLASLKTMVETKKVAGTGSGVLCLENYTDRMQVLKSLVHCADLSNPTKPLPIYRKWVDRLMEEFFRQGDKERDIDGMEISPMMDRHNASIEKSQVVFIDFVAQPLWETWGELVQPDAQDL-LDTIEDNRQWY 519

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO40948 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5Q9])

HSP 1 Score: 151.369 bits (381), Expect = 3.041e-42
Identity = 74/166 (44.58%), Postives = 107/166 (64.46%), Query Frame = 3

Query:  822 LKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQM------LYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREI 1301
            LK  SFN+W +   E++ L++ M+ +L L + F I +  L ++L  +  NY   PFHNF+H FCV QM      +Y +I+L NL+++  S +IL LM + + H LDHPG NN  QINA+T +A RYND SPLENHH A AF IL + + NI  +L ++ F K+R++
Sbjct:   13 LKKPSFNIWHWGPNEMVRLLEYMYHDLDLVSEFKINVNVLRRFLMCIQANYRNNPFHNFSHCFCVTQMAKSSLQMYGIIHLCNLKQLISSFDILILMTACVCHALDHPGYNNTNQINAQTEIAIRYNDTSPLENHHAATAFDILSQPEYNIFANLPEEMFTKIRKV 178

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO37301 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGA1])

HSP 1 Score: 155.606 bits (392), Expect = 1.025e-41
Identity = 93/250 (37.20%), Postives = 137/250 (54.80%), Query Frame = 3

Query:  918 FNIPLTTLDQWLFSVYQNY--NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNL-LPKLDLVNDSSHRIMLMV-VVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVF 1655
            F I   TLD++L  V   Y  ++ P+HN  HA  V   ++  +    + +    LE+  L+ SA+ HDL+H G  NAF IN+R+ LA  YND+S LENHH + AF+IL++ ++NIL  L  +Q+  +R + I  +L+TDM+ H      F  L L K+ LV  S      +V +++ + DISN  +   I   W   ++EEFF Q D+E   GL  +P  DR       SQ GFI F++ P  E+  EV 
Sbjct:  114 FKIHAMTLDRFLQDVETGYKRHSNPYHNDCHAADVTHTVHYFLECMGVSKYLSDLEVFGLLLSAIIHDLEHTGTTNAFHINSRSDLALLYNDRSVLENHHVSCAFRILQDDEKNILSGLNLEQYADVRSLMIDTVLATDMSSH------FEQLRLMKVALVAGSPIENREVVQLLLHVADISNPTKDWTIHRQWTTKIMEEFFTQGDMEIELGLDVSPLCDRSTTLIPESQIGFIDFIVSPALEVCSEVL 357

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BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO42681 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0H3])

HSP 1 Score: 144.05 bits (362), Expect = 1.011e-38
Identity = 88/249 (35.34%), Postives = 138/249 (55.42%), Query Frame = 3

Query:  945 QWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLL--PKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDL--EKLKGLPWAPFMDREKVTKSNS-QCGFIKFVIMPLFELFGEVFPSVEDLI 1676
            +WL SV +NY  V +HN+ HAF V Q ++ ++   +L + F  LE+  L+ + L HDLDH G NNAFQ    + LA  Y+  S +E+HH      IL  +  NI   ++ ++++   +I    ILSTD+  +      F+ +L  P +D   D++ R +L  +++  CD++   +P  I     E +  EFF Q DL  EKL   P  P MDR K  +  S Q GFI F+ +P++ELF ++ PS++ L+
Sbjct:    3 RWLLSVKKNYRPVKYHNWRHAFNVAQSMFTIMKTGSLCKYFSDLEVFALIVACLCHDLDHRGTNNAFQTKTDSPLAALYS-TSTMEHHHFDHCIMILNGEGNNIFSEMSPEEYRDTIKILEHAILSTDLALYFKKRGTFQEILAEPNVDWSADNN-RELLRAMMMTACDVAAITKPWEIQRVVAEMVASEFFDQGDLEKEKLNAEP-IPMMDRRKKNELPSMQVGFIDFICLPIYELFYKLEPSLKPLL 248

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: si:dkey-219c10.4 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [Source:NCBI gene;Acc:101166781])

HSP 1 Score: 382.104 bits (980), Expect = 2.725e-124
Identity = 211/531 (39.74%), Postives = 325/531 (61.21%), Query Frame = 3

Query:  138 ISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVIS--CCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKM-HLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
            +  ++IY       EQ E P  C   D++D+ RS + A   DI+KL +     +    + LEPN PS  Y +EV++  C  Q   + ++ G    L  ++ R+  +ER I  ++D   D  PS + E++ ++   +++ + + HLS                           +    + + +  H     + SP     ++ KT ++   V  ++  +   E+   VR  LKT +F+ W + DAE++ L+++M+ +L    +FNI   TL Q+LF VY+ YN +PFHNF H FCV QM+Y +I L +LR   DS+ +L ++ SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE ++ NI ++L+  Q+K++RE  IKCIL+TDMT+H +I+ +F++ LP  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV++PL     ++FP ++  I++PV+  L+YYT+++
Sbjct:    1 METKVIYFTVNGTPEQAEFPVDCPDQDVKDLFRSAAEAGPHDILKLYS-PKGSIINISTRLEPNSPSSCYRLEVVATDCSHQPPGAELAGGL--DLSSIEKRLQCLERNIL-IYD---DKTPSVVFEMKKQVDSFREKLENVEHLS---------------------------WLGLFKDLSEGTH-----KPSPFYHKRTLQKTREECERVREKFLQMSSLEVSEEVRNYLKTPTFDNWQWEDAEIMVLLQVMYTDLDFVASFNIEPETLQQFLFEVYRRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKMDSINLLIMLTSAVCHDLDHTGYNNAYQINARTDLALRYNDISPLENHHCAVAFEILERRESNIFRNLSPDQYKRIREGMIKCILATDMTRHNEILNKFKSTLPSFDFTN-KEHKDLLMMILIKVSDISNEARPMEVAEPWLDCLLQEFFNQSDVEKLEGLPVTPFMDRDKVTKPSSQIGFIRFVLLPLLIELTKLFPCLKHHIIEPVRKALDYYTEME 491

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: si:dkey-219c10.4 (high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [Source:NCBI gene;Acc:101166781])

HSP 1 Score: 361.688 bits (927), Expect = 6.055e-116
Identity = 173/361 (47.92%), Postives = 252/361 (69.81%), Query Frame = 3

Query:  651 FSNIQTMQQCIHLNDLSQS----SPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQ 1721
              N++ +       DLS+     SP     ++ KT ++   V  ++  +   E+   VR  LKT +F+ W + DAE++ L+++M+ +L    +FNI   TL Q+LF VY+ YN +PFHNF H FCV QM+Y +I L +LR   DS+ +L ++ SA+ HDLDH G NNA+QINART LA RYND SPLENHHCA+AF+ILE  + NI ++L+  Q+K++RE  IKCIL+TDMT+H +I+ +F++ LP  D  N   H+ +LM+++IK+ DISNEARP  ++EPWL+CLL+EFF QSD+EKL+GLP  PFMDR+KVTK +SQ GFI+FV++PL     ++FP ++  I++PV+  L+YYT+++
Sbjct:  119 LENVEHLSWLGLFKDLSEGTHKPSPFYHKRTLQKTREECERVREKFLQMSSLEVSEEVRNYLKTPTFDNWQWEDAEIMVLLQVMYTDLDFVASFNIEPETLQQFLFEVYRRYNNIPFHNFKHCFCVTQMMYGLIWLTDLRSKMDSINLLIMLTSAVCHDLDHTGYNNAYQINARTDLALRYNDISPLENHHCAVAFEILE--RSNIFRNLSPDQYKRIREGMIKCILATDMTRHNEILNKFKSTLPSFDFTN-KEHKDLLMMILIKVSDISNEARPMEVAEPWLDCLLQEFFNQSDVEKLEGLPVTPFMDRDKVTKPSSQIGFIRFVLLPLLIELTKLFPCLKHHIIEPVRKALDYYTEME 476

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde9al (phosphodiesterase 9A [Source:NCBI gene;Acc:101169304])

HSP 1 Score: 311.612 bits (797), Expect = 1.777e-97
Identity = 151/326 (46.32%), Postives = 218/326 (66.87%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAIS 1757
            S  K  + +   + LK  +F++W +   E+++ ++ M+ +L L   FN+   TL +WL ++ +NY   PFHNF H FCV QM+Y MI+L NL+E      +  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FKK+R+  I  IL+TDM +H +I+  F+  +   D  N+  H   L  V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+        DAIS
Sbjct:  157 SYPKYTLSQETIDALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRNNPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTNLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVDPEAFKKIRQGIITLILATDMARHGEILETFKLNVDHFDFTNE-EHVASLKTVMIKCCDISNEVRPAEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQ-----LEDAIS 476

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde9al (phosphodiesterase 9A [Source:NCBI gene;Acc:101169304])

HSP 1 Score: 311.997 bits (798), Expect = 2.753e-97
Identity = 151/326 (46.32%), Postives = 218/326 (66.87%), Query Frame = 3

Query:  780 SLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAIS 1757
            S  K  + +   + LK  +F++W +   E+++ ++ M+ +L L   FN+   TL +WL ++ +NY   PFHNF H FCV QM+Y MI+L NL+E      +  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FKK+R+  I  IL+TDM +H +I+  F+  +   D  N+  H   L  V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+        DAIS
Sbjct:  183 SYPKYTLSQETIDALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRNNPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTNLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVDPEAFKKIRQGIITLILATDMARHGEILETFKLNVDHFDFTNE-EHVASLKTVMIKCCDISNEVRPAEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQ-----LEDAIS 502

[Close]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde9al (phosphodiesterase 9A [Source:NCBI gene;Acc:101169304])

HSP 1 Score: 301.212 bits (770), Expect = 1.557e-93
Identity = 144/298 (48.32%), Postives = 205/298 (68.79%), Query Frame = 3

Query:  864 ELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAIS 1757
            ++++ ++ M+ +L L   FN+   TL +WL ++ +NY   PFHNF H FCV QM+Y MI+L NL+E      +  LM +A+ HDLDHPG NN +QINART LA RYND SPLENHHCA+AFQIL   + NI  ++  + FKK+R+  I  IL+TDM +H +I+  F+  +   D  N+  H   L  V+IK CDISNE RP  ++EPW++CLLEE+F QSD EK +GLP APFMDR+KVTK  +Q GFIKFV++P+FE   ++FP +E+++++P+++  ++Y +L+        DAIS
Sbjct:  186 KMLSCLEYMYHDLGLVKEFNMNPITLKRWLLAIQENYRNNPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTNLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVDPEAFKKIRQGIITLILATDMARHGEILETFKLNVDHFDFTNE-EHVASLKTVMIKCCDISNEVRPAEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKPTAQIGFIKFVLIPMFETVMKLFPQIEEIMVQPLRDSRDHYEELKQ-----LEDAIS 477

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BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000023094.1 (SMESG000023094.1)

HSP 1 Score: 1233.78 bits (3191), Expect = 0.000e+0
Identity = 619/621 (99.68%), Postives = 620/621 (99.84%), Query Frame = 3

Query:   99 MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS 1961
            MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHQNVVLSLNPSSLEPNLPSQPYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYP+HIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKA NPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS
Sbjct:    1 MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHQNVVLSLNPSSLEPNLPSQPYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPTHIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKAPNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS 621

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000023094.1 (SMESG000023094.1)

HSP 1 Score: 1216.83 bits (3147), Expect = 0.000e+0
Identity = 613/621 (98.71%), Postives = 614/621 (98.87%), Query Frame = 3

Query:   99 MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHXXXXXXXXXXXXXXXXXXXXYHVEVISCCPQLFTSLISQGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS 1961
            MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHQNVVLSLNPSSLEPNLPSQPYHVEVISCCPQLFTSLISQGARRSLQELDMR      KIQGLFDSFHDSYP+HIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKA NPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS
Sbjct:    1 MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISGANRRDIIKLTNHQNVVLSLNPSSLEPNLPSQPYHVEVISCCPQLFTSLISQGARRSLQELDMR------KIQGLFDSFHDSYPTHIVELESRIIKLQDRFQKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDLSQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKAPNPTADAISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRKTSTGSMPSRKSSTGSMVAAHS 615

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000020487.1 (SMESG000020487.1)

HSP 1 Score: 332.028 bits (850), Expect = 1.359e-104
Identity = 164/342 (47.95%), Postives = 234/342 (68.42%), Query Frame = 3

Query:  699 SQSSPMC-DWSSIGKTHKQIHTVWIQYQSLQKSEIRR-SVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL 1718
            ++S P C +  SI    + +  V  +Y+ L+  E +  ++ + L+ +SFN WS+SDAEL+  V+ MFI L+L + FNI +   D+W+F VY NYN VPFHNF HAF V QM+Y++I    L+    SL++L L+ +++SHDL+HPG NNA+QIN+ + LA RYNDQSPLENHH + A  IL     +I  HL  +Q + +R   IKCIL+TDM++H +I+  F+++L   D ++  SHR +LM+++IK  DISNEARP  ++  W++CL EEFF QS  EK  GLP APFMD+EKVTK+ SQCGFI+FVI PLFE   ++    ++ +L PV  QL+YY++L
Sbjct:  155 AESQPPCPNPESIVPLSQSLTIVLSEYKILKFDEKKEENLSKQLREISFNNWSYSDAELLYAVRKMFIELELFSEFNISIKKFDRWIFEVYCNYNMVPFHNFKHAFMVTQMMYSIIWEGKLKSKMSSLDVLVLLTASVSHDLNHPGFNNAYQINSGSELAIRYNDQSPLENHHLSTALYILNLPDCSIFSHLPTEQQRYIRSGMIKCILATDMSRHNEILNSFKSILANFDWLSQ-SHRDLLMMILIKASDISNEARPLDVASKWIDCLFEEFFNQSAFEKQSGLPVAPFMDKEKVTKAASQCGFIRFVIYPLFESLAQLISEYKEHLLIPVLRQLDYYSQL 495

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000020487.1 (SMESG000020487.1)

HSP 1 Score: 331.643 bits (849), Expect = 2.580e-104
Identity = 164/342 (47.95%), Postives = 234/342 (68.42%), Query Frame = 3

Query:  699 SQSSPMC-DWSSIGKTHKQIHTVWIQYQSLQKSEIRR-SVRENLKTLSFNMWSFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKL 1718
            ++S P C +  SI    + +  V  +Y+ L+  E +  ++ + L+ +SFN WS+SDAEL+  V+ MFI L+L + FNI +   D+W+F VY NYN VPFHNF HAF V QM+Y++I    L+    SL++L L+ +++SHDL+HPG NNA+QIN+ + LA RYNDQSPLENHH + A  IL     +I  HL  +Q + +R   IKCIL+TDM++H +I+  F+++L   D ++  SHR +LM+++IK  DISNEARP  ++  W++CL EEFF QS  EK  GLP APFMD+EKVTK+ SQCGFI+FVI PLFE   ++    ++ +L PV  QL+YY++L
Sbjct:  171 AESQPPCPNPESIVPLSQSLTIVLSEYKILKFDEKKEENLSKQLREISFNNWSYSDAELLYAVRKMFIELELFSEFNISIKKFDRWIFEVYCNYNMVPFHNFKHAFMVTQMMYSIIWEGKLKSKMSSLDVLVLLTASVSHDLNHPGFNNAYQINSGSELAIRYNDQSPLENHHLSTALYILNLPDCSIFSHLPTEQQRYIRSGMIKCILATDMSRHNEILNSFKSILANFDWLSQ-SHRDLLMMILIKASDISNEARPLDVASKWIDCLFEEFFNQSAFEKQSGLPVAPFMDKEKVTKAASQCGFIRFVIYPLFESLAQLISEYKEHLLIPVLRQLDYYSQL 511

[Close]

BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000077093.1 (SMESG000077093.1)

HSP 1 Score: 192.2 bits (487), Expect = 6.369e-52
Identity = 104/327 (31.80%), Postives = 181/327 (55.35%), Query Frame = 3

Query:  789 KSEIRRSVRENLKTLSFNMWSFSDAE----LINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNY-NTVPFHNFTHAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQINARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLREISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDS-------SHRIMLMVVVIKLCDISNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQCGFIKFVIMPLFELFGE-VFPSVEDLILKPVKNQLEYYTKLQNKA 1730
            + E+ + +  +LK    N++SF+D      L  +   +F +L L   F I   TL Q+L    ++Y NTVP+HN  HA  V Q    ++    L  +F  LEIL+++F+++ HD+DHPG+ N + +N    LA  YND S LENHH AMAF +L +++ + L  L+ +  + +R + I  +L+TDM+KH  ++ + + ++    +           + RI ++  ++   D+SN  +P HI + W++ ++EEF+ Q D E+   L  +P  DR+  +   SQ  FI F++ PL+E + E V+P  + ++    +N+  Y+ K Q K+
Sbjct:  338 EEEVSKILDSDLKKWGMNLFSFADVTADQPLAVVSYTIFKDLNLINKFQIDSKTLVQFLIKAERSYRNTVPYHNNMHAADVTQSANVLLAGQALENVFSDLEILSVIFASIIHDMDHPGVTNQYLVNTNNELATLYNDNSVLENHHLAMAFSLLAKEECDFLATLSKRHRQSMRRMVIDMVLATDMSKHMTLLADLKTMVETKKVAGSGILTLDTYTDRIQILQNLVHCADLSNPTKPLHIYQKWIDRVMEEFYLQGDKERESELEISPMCDRQTASLEKSQVSFIDFIVHPLWETWSELVYPDTQGMLEALEENRQFYFNKSQEKS 664

The following BLAST results are available for this feature:

BLAST of Phosphodiesterase vs. Ensembl Human
BLAST of Phosphodiesterase vs. Ensembl Celegans
BLAST of Phosphodiesterase vs. Ensembl Fly
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
BLAST of Phosphodiesterase vs. Ensembl Xenopus
BLAST of Phosphodiesterase vs. Ensembl Mouse
BLAST of Phosphodiesterase vs. UniProt/SwissProt
BLAST of Phosphodiesterase vs. TrEMBL
BLAST of Phosphodiesterase vs. Ensembl Cavefish
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
BLAST of Phosphodiesterase vs. Ensembl Yeast
BLAST of Phosphodiesterase vs. Ensembl Nematostella
BLAST of Phosphodiesterase vs. Ensembl Medaka
BLAST of Phosphodiesterase vs. Planmine SMEST

BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PDE9A	7.622e-101	49.67	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE9A	7.684e-101	49.67	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE9A	1.056e-100	49.67	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE9A	1.136e-100	49.67	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:...	[more]
PDE9A	1.702e-100	49.67	phosphodiesterase 9A [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pde-1	2.850e-50	32.73	Probable 3',5'-cyclic phosphodiesterase pde-1 [So...	[more]
pde-1	4.872e-50	32.73	Probable 3',5'-cyclic phosphodiesterase pde-1 [So...	[more]
pde-4	4.881e-48	34.41	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	5.174e-48	34.41	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]
pde-4	8.172e-48	34.41	Probable 3',5'-cyclic phosphodiesterase pde-4 [So...	[more]

BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pde9	5.367e-98	47.38	gene:FBgn0259171 transcript:FBtr0333524	[more]
Pde9	5.367e-98	47.38	gene:FBgn0259171 transcript:FBtr0299635	[more]
Pde9	5.367e-98	47.38	gene:FBgn0259171 transcript:FBtr0333525	[more]
Pde9	9.021e-98	47.38	gene:FBgn0259171 transcript:FBtr0330395	[more]
dnc	3.132e-47	32.89	gene:FBgn0000479 transcript:FBtr0070522	[more]

BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-219c10.4	2.122e-127	38.83	si:dkey-219c10.4 [Source:ZFIN;Acc:ZDB-GENE-081105-...	[more]
pde9a	5.570e-100	47.77	phosphodiesterase 9A [Source:ZFIN;Acc:ZDB-GENE-130...	[more]
pde9al	1.163e-98	47.13	phosphodiesterase 9A like [Source:ZFIN;Acc:ZDB-GEN...	[more]
FQ378016.1	3.772e-98	47.67	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
FQ378016.1	3.120e-97	47.67	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]

BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000043255.1	2.114e-75	51.58	pep primary_assembly:Xenopus_tropicalis_v9.1:7:651...	[more]
c16orf72	2.829e-74	41.20	chromosome 16 open reading frame 72 [Source:Xenbas...	[more]
c16orf72	7.883e-59	35.46	chromosome 16 open reading frame 72 [Source:Xenbas...	[more]
PDE4D	9.400e-50	32.17	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]
PDE4D	1.054e-49	32.17	phosphodiesterase 4D [Source:NCBI gene;Acc:1004964...	[more]

BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pde9a	2.739e-100	49.01	phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:12...	[more]
Pde9a	2.826e-100	49.01	phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:12...	[more]
Pde9a	2.826e-100	49.01	phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:12...	[more]
Pde9a	1.724e-99	49.01	phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:12...	[more]
Pde9a	1.911e-99	49.01	phosphodiesterase 9A [Source:MGI Symbol;Acc:MGI:12...	[more]

BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|H2QL32\|PDE9A_PANTR	1.228e-99	49.67	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
sp\|O76083\|PDE9A_HUMAN	3.042e-99	49.67	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
sp\|Q8QZV1\|PDE9A_RAT	1.785e-98	49.01	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
sp\|O70628\|PDE9A_MOUSE	2.252e-98	49.01	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
sp\|Q9I7S6\|PDE9A_DROME	5.379e-97	47.38	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]

BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A401SLV9	7.247e-128	39.61	Phosphodiesterase OS=Chiloscyllium punctatum OX=13...	[more]
A0A1S3JYR8	1.148e-127	42.56	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
A0A1S3JZ65	1.916e-126	42.40	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]
W5M2C2	4.047e-126	38.46	Phosphodiesterase OS=Lepisosteus oculatus OX=7918 ...	[more]
A0A1S3JYL5	4.710e-126	41.95	Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC...	[more]

BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-219c10.4	2.192e-125	39.17	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
si:dkey-219c10.4	1.591e-119	50.29	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
pde9a	1.206e-101	47.66	phosphodiesterase 9A [Source:NCBI gene;Acc:1030284...	[more]
pde9a	1.804e-101	46.27	phosphodiesterase 9A [Source:NCBI gene;Acc:1030284...	[more]
pde9a	8.377e-101	47.77	phosphodiesterase 9A [Source:NCBI gene;Acc:1030284...	[more]

BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-219c10.4	2.825e-68	57.71	si:dkey-219c10.4 [Source:ZFIN;Acc:ZDB-GENE-081105-...	[more]
pde9al	5.120e-66	39.55	phosphodiesterase 9A like [Source:ZFIN;Acc:ZDB-GEN...	[more]
PDE2A	9.624e-41	28.91	phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:...	[more]
pde1a	3.336e-40	27.46	phosphodiesterase 1A, calmodulin-dependent [Source...	[more]
PDE1C	2.035e-38	28.95	phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
PDE2	1.120e-13	31.02	High-affinity cyclic AMP phosphodiesterase; compon...	[more]

BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO32179	3.168e-117	39.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46133	9.339e-44	30.91	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40948	3.041e-42	44.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37301	1.025e-41	37.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42681	1.011e-38	35.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-219c10.4	2.725e-124	39.74	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
si:dkey-219c10.4	6.055e-116	47.92	high affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]
pde9al	1.777e-97	46.32	phosphodiesterase 9A [Source:NCBI gene;Acc:1011693...	[more]
pde9al	2.753e-97	46.32	phosphodiesterase 9A [Source:NCBI gene;Acc:1011693...	[more]
pde9al	1.557e-93	48.32	phosphodiesterase 9A [Source:NCBI gene;Acc:1011693...	[more]

BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000023094.1	0.000e+0	99.68	SMESG000023094.1	[more]
SMESG000023094.1	0.000e+0	98.71	SMESG000023094.1	[more]
SMESG000020487.1	1.359e-104	47.95	SMESG000020487.1	[more]
SMESG000020487.1	2.580e-104	47.95	SMESG000020487.1	[more]
SMESG000077093.1	6.369e-52	31.80	SMESG000077093.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30002297 ID=SMED30002297|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=2253bp
CAAATTTTTAAAGTTATTATATATATCAAAATTTCATTAATATAATTTTC
AATGGATTTGAATATTTTGAAAGTTTTATGTTGAACTAGTATGATAAAAT
GGGTGAACGAAGAGAAAGAAAGAAAAGTATTCTTTATATAAGCAATAGAA
TCATATATGTTAAAACCGCAACAAAATTGGAGCAGATTGAACTTCCACCT
CAATGTACATTCGATGATATTGAAGATGTTCTCAGATCTATCAGTGGGGC
CAATCGACGGGATATTATCAAGTTGACAAATCACCAAAATGTCGTGCTAT
CTTTAAATCCATCAAGTTTAGAACCTAACCTCCCTAGTCAACCATATCAT
GTGGAAGTCATCAGCTGCTGTCCGCAATTATTTACGTCATTGATCAGCCA
AGGTGCAAGACGGTCACTGCAGGAATTGGACATGAGGATAGATAATGTTG
AAAGGAAAATTCAAGGTTTATTCGACAGCTTCCATGATTCATATCCTAGT
CACATTGTTGAGCTTGAAAGCCGAATAATTAAGCTCCAAGATAGATTTCA
GAAAATGCATCTCAGTCGACAATTGAGCCGGGAAAATCCCAACACAATTA
GACCAAGAAATACCAGTGAAATATCTGCCCGTTGTTCTATTTGCCCATAT
TTTTCTAATATCCAAACCATGCAGCAATGTATCCACCTGAATGATCTTAG
CCAGTCTAGTCCAATGTGTGACTGGTCTAGCATTGGGAAAACACATAAAC
AAATTCATACAGTTTGGATCCAATATCAGTCACTTCAAAAGAGTGAAATC
CGACGAAGTGTCCGTGAGAATTTAAAGACTTTATCATTCAACATGTGGAG
CTTTTCTGATGCTGAACTGATCAACCTTGTGAAGCTTATGTTCATCAATT
TACAATTAACAACGGCTTTCAACATTCCTTTAACCACACTTGACCAATGG
CTATTTTCTGTCTACCAGAACTATAATACCGTCCCCTTTCATAATTTCAC
TCACGCATTTTGTGTCGTACAAATGTTGTATGCAATGATAAATCTTGCAA
ATTTGCGAGAAATATTTGATAGTTTGGAAATTCTTACCTTGATGTTTTCA
GCACTATCCCATGACCTTGACCATCCAGGATTAAATAATGCATTCCAAAT
TAATGCCAGAACGTGTTTGGCTCAAAGATATAATGACCAGTCTCCATTGG
AAAATCATCATTGCGCAATGGCGTTTCAGATATTAGAAGAAAAGAAAAGA
AACATATTGAAGCATTTGACAGATAAACAGTTTAAGAAATTGAGAGAGAT
TTCAATCAAGTGTATTTTATCAACTGACATGACAAAACATGCCGATATTG
TGACAGAATTTCGGAACCTGCTACCGAAATTGGACCTAGTCAATGACAGT
TCTCATAGAATTATGCTCATGGTCGTGGTCATTAAGCTCTGTGACATATC
CAATGAAGCTCGCCCACCGCATATTTCAGAGCCATGGCTTGAATGTTTGT
TGGAAGAATTTTTTCAACAGAGTGATCTTGAAAAGTTGAAAGGATTACCA
TGGGCACCTTTTATGGACAGAGAAAAAGTGACAAAATCTAATAGCCAATG
TGGATTCATAAAATTCGTAATTATGCCTTTGTTTGAACTGTTTGGGGAAG
TATTTCCCTCGGTAGAAGACCTCATTTTAAAACCGGTAAAGAATCAATTA
GAATATTATACAAAACTTCAAAATAAAGCCTCCAACCCAACCGCTGACGC
AATCTCAGGGCCATTAACCGTTTCAAATATAACGCCAATTAGGAAAACGT
CAACAGGTTCTATTCCATCTAGGAAATCTAGTTTGGGTACCATATCACGA
CGACCTTCATTCTCGATTCTCGATGGAGCTTTACCTCCGGTTCGGAAAAC
CTCGACCGGATCCATGCCGTCAAGGAAATCGAGTACCGGCTCAATGGTTG
CTGCGCATAGTTAATTTTTGCAATTATACGGCTTACACTGACAAATGTGG
CATTTATATTAACAAATATTATATTAGCTTCACACTGGACAGTGATTATA
AATTGTCATGAAATTATATTTTGATTTATCGAATTTAAATGTGCTTGTGT
TGTGCTGGATCGATGTTTTATAATATAATTCAATTTTTATGAATTTCTCG
GTAAAGCTTATGTCTGATTCTCTTTGATTGTTTTTTGTTTATATTTTGTA
TAATCTTCTTTTGATTTGTTGTATTTATCGCTTTTTCGAATTATTTCAAG
ATT

protein sequence of SMED30002297-orf-1

>SMED30002297-orf-1 ID=SMED30002297-orf-1|Name=SMED30002297-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=622bp
MGERRERKKSILYISNRIIYVKTATKLEQIELPPQCTFDDIEDVLRSISG
ANRRDIIKLTNHQNVVLSLNPSSLEPNLPSQPYHVEVISCCPQLFTSLIS
QGARRSLQELDMRIDNVERKIQGLFDSFHDSYPSHIVELESRIIKLQDRF
QKMHLSRQLSRENPNTIRPRNTSEISARCSICPYFSNIQTMQQCIHLNDL
SQSSPMCDWSSIGKTHKQIHTVWIQYQSLQKSEIRRSVRENLKTLSFNMW
SFSDAELINLVKLMFINLQLTTAFNIPLTTLDQWLFSVYQNYNTVPFHNF
THAFCVVQMLYAMINLANLREIFDSLEILTLMFSALSHDLDHPGLNNAFQ
INARTCLAQRYNDQSPLENHHCAMAFQILEEKKRNILKHLTDKQFKKLRE
ISIKCILSTDMTKHADIVTEFRNLLPKLDLVNDSSHRIMLMVVVIKLCDI
SNEARPPHISEPWLECLLEEFFQQSDLEKLKGLPWAPFMDREKVTKSNSQ
CGFIKFVIMPLFELFGEVFPSVEDLILKPVKNQLEYYTKLQNKASNPTAD
AISGPLTVSNITPIRKTSTGSIPSRKSSLGTISRRPSFSILDGALPPVRK
TSTGSMPSRKSSTGSMVAAHS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal
PLANA:0000418	head
PLANA:0002056	medial muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036971	PDEase_catalytic_dom_sf
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR002073	PDEase_catalytic_dom
IPR023174	PDEase_CS

Vocabulary: **molecular function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 100..127
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 593..621
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 601..621
None	No IPR available	PANTHER	PTHR11347	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	coord: 185..543
None	No IPR available	PANTHER	PTHR11347:SF141	HIGH AFFINITY CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 9A	coord: 185..543
None	No IPR available	SUPERFAMILY	SSF109604	HD-domain/PDEase-like	coord: 236..548
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 338..353 score: 52.75 coord: 445..458 score: 27.86 coord: 324..337 score: 36.0 coord: 462..478 score: 45.18 coord: 365..381 score: 45.53 coord: 293..306 score: 42.0
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 295..463 e-value: 2.3E-4 score: 30.5
IPR003607	HD/PDEase domain	CDD	cd00077	HDc	coord: 298..472 e-value: 1.15157E-12 score: 63.8977
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 297..526 e-value: 3.4E-81 score: 272.5
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PROSITE	PS51845	PDEASE_I_2	coord: 222..544 score: 107.307
IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	GENE3D	G3DSA:1.10.1300.10		coord: 232..549 e-value: 5.5E-114 score: 382.4
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I_1	coord: 338..349