SAM and SH3 domain-containing protein

Overview
NameSAM and SH3 domain-containing protein
Smed IDSMED30002259
Length (bp)2004
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002259

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30002259h1SMcG0000350 Contig40774uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002259h1SMcG0000350 Contig40774newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30002259h1SMcG0000350 dd_Smed_v4_16294_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30002259h1SMcG0000350 dd_Smed_v4_16294_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Match: A0A4S2L8P7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009171 PE=4 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 9.924e-21
Identity = 59/141 (41.84%), Postives = 76/141 (53.90%), Query Frame = 2 
Query: 1481 GNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMY-------KGKIRIKCRNLQT-----FLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQI 1867
            G + IPLRL +RYA+EL  D+  VA+ ME  R  +L E  R V S +D I S ++LNCDGIKT S++ FL  IGLPMY        G      +  Q+      L  SD  LI        H+ W+RRE+S  P   LSQ+
Sbjct:    2 GQANIPLRLTQRYAFELGWDLSMVAILMEAEREHRLREAGRPVVSFIDDIQSQRYLNCDGIKTGSIEDFLIGIGLPMYIDHVKRMSGSFSNSSQPEQSITPVQLLKMSDTELINEIGFTKGHLDWLRRESSVIPSVLLSQL 142
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Match: A0A4Z2DK78 (SAM and SH3 domain-containing protein OS=Schistosoma japonicum OX=6182 GN=EWB00_000141 PE=4 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 6.948e-20
Identity = 61/159 (38.36%), Postives = 83/159 (52.20%), Query Frame = 2 
Query: 1469 SVQKGNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKI------------------RIKCRNLQTFLL-------YSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQIS 1870
            S + G++ IPLRL +RY++E + D+  VA+A+E  R   L E  R V S  + I S +FLNCDGIKT SL  FL +IGLPMY   I                    K  N Q+ ++        SD  L   FN  P H++W+R+EAS  P   L Q++
Sbjct:  515 SDETGHANIPLRLTQRYSFETNLDLMTVAMALEAERDANLREIRRPVISFNEEIQSQRFLNCDGIKTGSLQEFLITIGLPMYINHILHYSNITTTNNNNSSINSGNKNTNHQSIIMTPADLLNMSDCQLQEKFNFLPIHIQWLRQEASVIPWILLGQLN 673

HSP 2 Score: 28.8758 bits (63), Expect = 6.948e-20
Identity = 14/29 (48.28%), Postives = 16/29 (55.17%), Query Frame = 1 
Query: 1363 RQSVERKLQFEQIDFTDIPYSDQVKFAII 1449
            R  + RKL  E ID T  PYSD+   A I
Sbjct:  495 RHILRRKLTAEHIDLTQPPYSDETGHANI 523
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Match: A0A0R3UID5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS7182 PE=4 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.141e-19
Identity = 59/135 (43.70%), Postives = 76/135 (56.30%), Query Frame = 2 
Query: 1481 GNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCR--------NLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLS 1861
            G SGIPLRLIERYA E ++D   +AL +E  R   L +      SN++ I S ++LNC+GIKTD+L  FLT+IGLPMY   +    R        NL T    +D  +I +  I   HVR IR EA+  P   LS
Sbjct:   71 GGSGIPLRLIERYACEAEKDCTTIALTLERIREQILRKAQLPFASNLEEIHSRRYLNCNGIKTDNLGDFLTTIGLPMYAECLTTALRGNNAPIPANLSTL---TDAEMIFSLGIPVEHVRRIRAEAALIPRNHLS 202
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Match: A0A5K3EXX5 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.803e-19
Identity = 59/135 (43.70%), Postives = 76/135 (56.30%), Query Frame = 2 
Query: 1481 GNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCR--------NLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLS 1861
            G SGIPLRLIERYA E ++D   +AL +E  R   L +      SN++ I S ++LNC+GIKTD+L  FLT+IGLPMY   +    R        NL T    +D  +I +  I   HVR IR EA+  P   LS
Sbjct:   92 GGSGIPLRLIERYACEAEKDCTTIALTLERIREQILRKAQLPFASNLEEIHSRRYLNCNGIKTDNLGDFLTTIGLPMYAECLTTALRGNNAPIPANLSTL---TDAEMIFSLGIPVEHVRRIRAEAALIPRNHLS 223
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Match: A0A5J4NW38 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0002565 PE=4 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 1.991e-19
Identity = 64/168 (38.10%), Postives = 87/168 (51.79%), Query Frame = 2 
Query: 1481 GNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCRNLQT------------------FLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQIS----HVPPQRFRTTSDAKYF 1918
            G + IPLRL +RYA EL  +   VA+A+E  R  KL E  R V S MD I S ++LNCDGIKT +++ FL S+GLPMY  +I+    N Q                    L  SD+ LI++     +H+RW+R EA+  P    +Q S    H+ P      S A+ F
Sbjct:  136 GQADIPLRLTQRYASELGLEWTTVAIALEAEREAKLREAGRPVISFMDDIQSQRYLNCDGIKTGTVEDFLISLGLPMYIDRIKQLPMNGQPSPDPSIHSPSGYPVGPVDILKMSDQDLIKHLGFTWNHIRWLRIEAAMIPSIMRAQASFGTTHMKPSGSHMNSLAREF 303
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BLAST of SAM and SH3 domain-containing protein vs. Planmine SMEST
Match: SMESG000011174.1 (SMESG000011174.1)

HSP 1 Score: 825.083 bits (2130), Expect = 0.000e+0
Identity = 433/437 (99.08%), Postives = 435/437 (99.54%), Query Frame = 1 
Query:  121 MSFNENAGSSSLTNFIRSRVSRFGRFGLSKKYQRVLMTPLSDDQRKTVIDKLTKKGLQPQPEWNKQNKSEIPLPKKPDEFDRKKVTFESHSRNSVYFDSTSRLMEELLSSAPSSPTMSERSKFIRPGALNLNLDPGXXXXXXXXXXXXXXXXXGYYDTIPLLPECRDNSKEFFHSTNVPFKSFFPFPANESPFNQIPHYPDDRSRFVIGSEEPTTATNENIHVRRSRVQSLSHLLEKLQIKDLLPTFKIFGIEDLRAFTKLTEVMLDRMHITSTEVKTKILTALELLSETEDCPENEVFEKSKSIDPSTKSNSSHLQPQLDISDQGQMNQSVIRKPSSYHLSRSHRAARDMKGSSTRQPSGHRKHIXXXXXXXXXQKNRPYQTQISDLPHCSSGFFGQPLLQWKLPDPRESEKTRQSVERKLQFEQIDFTDIPYSDQ 1431
            MSFNENAGSSSLTNFIRSRVSRFGRFGLSKKYQRVLMTPLSDDQRKTVIDKLTKKGLQPQPEWNKQNKSEIPLPKKPDEFDRKKVTFESHSRNSVYFDSTSRLMEELLSSAPSSPTMSERSKFIRPGALNLNLDPGQISDVSQSAPSSPS+DIGYYDTIPLLPECRDNSKEFFHSTNVPFKSFFPFPANESPFNQIPHYPDDRSRFVIGSEEPTTATNENIHVRRSRVQSLSHLLEKLQIKDLLPTFKIFGIEDLRAFTKLTEVMLDRM ITSTEVKTKILTALELLSETEDCPENE FEKSKSIDPSTKSNSSHLQPQLDI+DQGQMNQSVIRKPSSYHLSRSHRAARDMKGSSTRQPSGHRKHISSKRSGSSSQKNRPYQTQISDLPHCSSGFFGQPLLQWKLPDPRESEKTRQSVERKLQFEQIDFTDIPYSDQ
Sbjct:    1 MSFNENAGSSSLTNFIRSRVSRFGRFGLSKKYQRVLMTPLSDDQRKTVIDKLTKKGLQPQPEWNKQNKSEIPLPKKPDEFDRKKVTFESHSRNSVYFDSTSRLMEELLSSAPSSPTMSERSKFIRPGALNLNLDPGQISDVSQSAPSSPSIDIGYYDTIPLLPECRDNSKEFFHSTNVPFKSFFPFPANESPFNQIPHYPDDRSRFVIGSEEPTTATNENIHVRRSRVQSLSHLLEKLQIKDLLPTFKIFGIEDLRAFTKLTEVMLDRMQITSTEVKTKILTALELLSETEDCPENEGFEKSKSIDPSTKSNSSHLQPQLDINDQGQMNQSVIRKPSSYHLSRSHRAARDMKGSSTRQPSGHRKHISSKRSGSSSQKNRPYQTQISDLPHCSSGFFGQPLLQWKLPDPRESEKTRQSVERKLQFEQIDFTDIPYSDQ 437

HSP 2 Score: 321.242 bits (822), Expect = 0.000e+0
Identity = 154/155 (99.35%), Postives = 154/155 (99.35%), Query Frame = 2 
Query: 1469 SVQKGNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCRNLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQISHVPPQRFRTTSDAKYFALDRV 1933
            S QKGNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCRNLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQISHVPPQRFRTTSDAKYFALDRV
Sbjct:  435 SDQKGNSGIPLRLIERYAYELDRDIRDVALAMETSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPMYKGKIRIKCRNLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLSQISHVPPQRFRTTSDAKYFALDRV 589
The following BLAST results are available for this feature:
BLAST of SAM and SH3 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2L8P79.924e-2141.84Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A4Z2DK786.948e-2038.36SAM and SH3 domain-containing protein OS=Schistoso... [more]
A0A0R3UID51.141e-1943.70Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3EXX51.803e-1943.70Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5J4NW381.991e-1938.10Uncharacterized protein OS=Paragonimus westermani ... [more]
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SAM and SH3 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000011174.10.000e+099.08SMESG000011174.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002259 ID=SMED30002259|Name=SAM and SH3 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2004bp
TGTGAAATCAATTCGAGATTTTCAATTATAATCAGCGACTGCGGTGCTAT
AGCTTCATTTAATATTTCGTTATGTTGGTGCTTGATTATTATTGTATAAA
TACTGCCGGTTGCTGTTGCTATGAGTTTTAATGAAAATGCCGGATCGTCG
AGTCTCACCAACTTCATCCGGAGCAGGGTTTCCAGGTTCGGGAGGTTTGG
ATTATCTAAAAAATATCAGCGAGTCCTAATGACACCCTTGTCGGATGACC
AAAGAAAAACAGTCATTGACAAATTAACCAAAAAAGGTTTACAGCCTCAA
CCTGAATGGAATAAACAGAACAAGTCAGAGATTCCACTTCCAAAGAAACC
AGATGAGTTTGATAGAAAAAAAGTTACATTTGAAAGTCATTCGAGAAATA
GTGTTTATTTTGATTCGACATCTAGATTAATGGAAGAGTTATTATCTTCT
GCTCCAAGCAGTCCAACGATGAGTGAAAGATCAAAATTTATACGACCAGG
AGCTTTGAATTTAAATCTTGACCCTGGTCAAATTTCTGACGTGAGCCAAT
CTGCTCCAAGCAGTCCAAGTGTTGACATTGGTTATTACGACACAATTCCA
CTTCTTCCTGAATGTAGAGATAACTCAAAAGAATTTTTCCATTCAACTAA
TGTTCCTTTTAAGTCTTTCTTTCCATTTCCAGCAAATGAATCACCATTCA
ATCAAATACCTCATTATCCCGATGACCGTTCACGATTTGTGATTGGCTCG
GAAGAACCAACAACGGCTACCAATGAAAATATTCATGTACGAAGAAGCAG
AGTTCAGTCTTTGTCTCACTTGCTTGAAAAGCTTCAAATTAAAGATTTGT
TACCGACTTTTAAAATATTTGGAATAGAAGATCTCAGGGCTTTCACAAAA
CTTACCGAAGTCATGCTGGATCGAATGCATATAACCAGCACGGAAGTAAA
AACAAAAATACTAACCGCATTGGAACTGCTTTCAGAAACAGAAGACTGTC
CAGAAAATGAGGTGTTCGAAAAGTCAAAATCAATTGATCCCTCCACAAAA
TCCAACTCGAGCCATTTACAACCTCAGTTGGATATTAGTGACCAAGGACA
AATGAATCAATCTGTCATAAGGAAGCCCAGCAGTTATCATTTGAGTAGAT
CGCACAGGGCTGCAAGGGACATGAAAGGCAGCTCTACTAGACAGCCTAGT
GGACACAGAAAGCATATTTCCTCAAAGAGATCTGGATCAAGTTCGCAGAA
AAATAGACCATATCAAACTCAGATTTCTGATTTACCTCATTGCAGCTCTG
GATTTTTTGGTCAACCTTTACTTCAATGGAAGCTTCCTGATCCAAGAGAA
TCTGAAAAGACAAGACAATCGGTAGAAAGAAAACTCCAATTCGAACAAAT
AGATTTCACTGATATTCCCTATTCAGACCAAGTTAAGTTTGCGATAATAT
GCTACAATTTATTTACGATCAGTGCAGAAAGGGAACTCGGGCATACCACT
GCGTTTAATTGAAAGATATGCCTATGAATTAGACAGAGACATCAGAGATG
TTGCATTGGCAATGGAAACGAGTCGAAGTGACAAGTTGTTAGAGCATAAT
CGTGATGTGCGGTCAAACATGGACGCAATTCTGTCAGATCAGTTCCTCAA
CTGTGACGGCATTAAAACAGACAGTCTTGACAGTTTCCTGACATCAATCG
GTTTGCCGATGTACAAAGGGAAAATCCGTATTAAATGTCGAAATCTTCAA
ACTTTTTTGTTATATTCTGATGAAGCCTTGATAAGAAATTTCAACATCCA
CCCGTCCCATGTCCGGTGGATCCGACGAGAGGCTTCTTTTTTTCCAATTG
GATTTCTTAGTCAAATATCCCATGTTCCACCGCAGAGATTTAGAACGACG
TCCGACGCAAAGTATTTTGCTCTTGATCGAGTTTAATTAAATATGTTGAT
CTTCATGTTACATTTTGAAGTATTGATACTGATGTATAAATTGTTTTGCT
AGAG
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protein sequence of SMED30002259-orf-1

>SMED30002259-orf-1 ID=SMED30002259-orf-1|Name=SMED30002259-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=464bp
MSFNENAGSSSLTNFIRSRVSRFGRFGLSKKYQRVLMTPLSDDQRKTVID
KLTKKGLQPQPEWNKQNKSEIPLPKKPDEFDRKKVTFESHSRNSVYFDST
SRLMEELLSSAPSSPTMSERSKFIRPGALNLNLDPGQISDVSQSAPSSPS
VDIGYYDTIPLLPECRDNSKEFFHSTNVPFKSFFPFPANESPFNQIPHYP
DDRSRFVIGSEEPTTATNENIHVRRSRVQSLSHLLEKLQIKDLLPTFKIF
GIEDLRAFTKLTEVMLDRMHITSTEVKTKILTALELLSETEDCPENEVFE
KSKSIDPSTKSNSSHLQPQLDISDQGQMNQSVIRKPSSYHLSRSHRAARD
MKGSSTRQPSGHRKHISSKRSGSSSQKNRPYQTQISDLPHCSSGFFGQPL
LQWKLPDPRESEKTRQSVERKLQFEQIDFTDIPYSDQVKFAIICYNLFTI
SAERELGHTTAFN*
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protein sequence of SMED30002259-orf-2

>SMED30002259-orf-2 ID=SMED30002259-orf-2|Name=SMED30002259-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=125bp
METSRSDKLLEHNRDVRSNMDAILSDQFLNCDGIKTDSLDSFLTSIGLPM
YKGKIRIKCRNLQTFLLYSDEALIRNFNIHPSHVRWIRREASFFPIGFLS
QISHVPPQRFRTTSDAKYFALDRV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR013761SAM/pointed_sf
Vocabulary: biological process
TermDefinition
GO:0000209protein polyubiquitination
GO:0010595positive regulation of endothelial cell migration
GO:0031666positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043507positive regulation of JUN kinase activity
GO:0045766positive regulation of angiogenesis
GO:1900044regulation of protein K63-linked ubiquitination
GO:1900745positive regulation of p38MAPK cascade
GO:1901224positive regulation of NIK/NF-kappaB signaling
GO:1902498regulation of protein autoubiquitination
Vocabulary: molecular function
TermDefinition
GO:0008022protein C-terminus binding
GO:0019901protein kinase binding
GO:0031435mitogen-activated protein kinase kinase kinase binding
GO:0032947protein complex scaffold
Vocabulary: cellular component
TermDefinition
GO:0043234protein complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013761Sterile alpha motif/pointed domain superfamilyGENE3DG3DSA:1.10.150.50coord: 220..292
e-value: 2.0E-7
score: 32.9
IPR013761Sterile alpha motif/pointed domain superfamilySUPERFAMILYSSF47769SAM/Pointed domaincoord: 223..290
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 335..381
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 291..316
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 53..77