non-canonical poly(A) RNA polymerase PAPD5-like

Overview


Name	non-canonical poly(A) RNA polymerase PAPD5-like
Smed ID	SMED30002251
Length (bp)	2007

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of non-canonical poly(A) RNA polymerase PAPD5-like (SMED30002251) t-SNE clustered cells

Violin plots show distribution of expression levels for non-canonical poly(A) RNA polymerase PAPD5-like (SMED30002251) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of non-canonical poly(A) RNA polymerase PAPD5-like (SMED30002251) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002251

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
gut	SMED30002251	h1SMcG0021046	dd_Smed_v4_5011_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

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Homology

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Match: TENT4A (terminal nucleotidyltransferase 4A [Source:HGNC Symbol;Acc:HGNC:16705])

HSP 1 Score: 340.887 bits (873), Expect = 6.914e-106
Identity = 196/402 (48.76%), Postives = 267/402 (66.42%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMF----------PWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSN 1527
            +RKRE NKAST+G +  L     + ++              PW  K++ Y   + GLHEEI+DFYN++ P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      +  S LGRII++T EV+ YR  IKEK+  K  P      +++ IK  E+I+  + ++  N
Sbjct:  187 RRKRE-NKASTYGLNYLLSGSRAAALSGGGGPGAQAPRPGTPW--KSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDAESTLGRIIKVTQEVIDYRRWIKEKWGSKAHPSP---GMDSRIKIKERIATCNGEQTQN 582

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Match: TENT4B (terminal nucleotidyltransferase 4B [Source:HGNC Symbol;Acc:HGNC:30758])

HSP 1 Score: 333.569 bits (854), Expect = 7.788e-105
Identity = 198/378 (52.38%), Postives = 256/378 (67.72%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQL-----------QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAST+G +  L                  V     PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  K  PE
Sbjct:   78 KRKRD-NKASTYGLNYSLLQPSGGRAAGGGRADGGGVVYSGTPWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPE 451

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Match: TENT4B (terminal nucleotidyltransferase 4B [Source:HGNC Symbol;Acc:HGNC:30758])

HSP 1 Score: 333.569 bits (854), Expect = 3.471e-104
Identity = 198/378 (52.38%), Postives = 256/378 (67.72%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQL-----------QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAST+G +  L                  V     PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  K  PE
Sbjct:  145 KRKRD-NKASTYGLNYSLLQPSGGRAAGGGRADGGGVVYSGTPWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPE 518

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Match: TENT4A (terminal nucleotidyltransferase 4A [Source:HGNC Symbol;Acc:HGNC:16705])

HSP 1 Score: 300.827 bits (769), Expect = 1.894e-93
Identity = 171/333 (51.35%), Postives = 230/333 (69.07%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSN 1527
            P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      +  S LGRII++T EV+ YR  IKEK+  K  P      +++ IK  E+I+  + ++  N
Sbjct:    3 PCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDAESTLGRIIKVTQEVIDYRRWIKEKWGSKAHPSP---GMDSRIKIKERIATCNGEQTQN 332

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Match: TENT4B (terminal nucleotidyltransferase 4B [Source:HGNC Symbol;Acc:HGNC:30758])

HSP 1 Score: 271.937 bits (694), Expect = 1.777e-85
Identity = 158/278 (56.83%), Postives = 203/278 (73.02%), Query Frame = 1

Query:  637 VFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  K  PE
Sbjct:    2 IFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPE 278

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Celegans
Match: gld-4 (Poly(A) RNA polymerase gld-4 [Source:UniProtKB/Swiss-Prot;Acc:G5EFL0])

HSP 1 Score: 180.644 bits (457), Expect = 1.036e-47
Identity = 131/360 (36.39%), Postives = 196/360 (54.44%), Query Frame = 1

Query:  403 FGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEA--KVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLNDIIKKSG-------IASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKINSQE------NLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEI-LKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQ--------SAQLYEGNTSILGRIIRITPEVMKYRN 1410
            FGY   L F           PW  + K Y  N+ GLHEEI+D Y++I P   E  +R +V  ++++ VL+ W +   K+ +FGS +T L LPTSDIDV++  + D+ + T  D + ++        IA    V   A VPIVKM D++T + IDISFN   G+++A+ I    +E+P +  LVLLLKQ+L  R+LN+ +TGG+SSY L+L+ V+F +L A  + S+       NLG  L+ FLELY   F++   GI + G  C++PK     +          L +EDPL   ND+GRS+Y    I  AF  A+  L   +  +        + + Y+G  S+L  I+  T + + YRN
Sbjct:   57 FGYSDSLPFA----------PW--RRKRYGLNIQGLHEEIVDMYHWIKPNEIESRLRTKVFEKVRDSVLRRWKQKTIKISMFGSLRTNLFLPTSDIDVLV--ECDDWVGTPGDWLAETARGLEADNIAESVMVYGGAFVPIVKMVDRDTRLSIDISFNTVQGVRAASYIAKVKEEFPLIEPLVLLLKQFLHYRNLNQTFTGGLSSYGLVLLLVNFFQLYALNMRSRTIYDRGVNLGHLLLRFLELYSLEFNFEEMGI-SPGQCCYIPKSASGARYGHKQAQPGNLALEDPLLTANDVGRSTYNFSSIANAFGQAFQILLVAVTLRERKGKNHVAMRAYKG--SLLHLIMPFTSKELTYRN 399

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Match: Trf4-1 (gene:FBgn0030049 transcript:FBtr0112964)

HSP 1 Score: 310.457 bits (794), Expect = 1.033e-94
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:   28 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 383

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Match: Trf4-1 (gene:FBgn0030049 transcript:FBtr0112963)

HSP 1 Score: 310.457 bits (794), Expect = 1.033e-94
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:   28 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 383

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Match: Trf4-1 (gene:FBgn0030049 transcript:FBtr0331724)

HSP 1 Score: 310.071 bits (793), Expect = 5.033e-93
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:  227 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 582

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Match: Trf4-1 (gene:FBgn0030049 transcript:FBtr0071212)

HSP 1 Score: 310.071 bits (793), Expect = 5.033e-93
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:  227 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 582

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Match: Trf4-1 (gene:FBgn0030049 transcript:FBtr0071213)

HSP 1 Score: 310.071 bits (793), Expect = 5.033e-93
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:  227 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 582

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
Match: tent4b (terminal nucleotidyltransferase 4B [Source:ZFIN;Acc:ZDB-GENE-041021-2])

HSP 1 Score: 337.421 bits (864), Expect = 2.618e-106
Identity = 193/369 (52.30%), Postives = 260/369 (70.46%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKK--INSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT--SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQI 1455
            KRKR+ NKAST+G++  L     +       PW  +N  Y   + GLHEEI DFY YI P  EE++MR EVVAR++ V+   WP A+V VFGSF T L+LPTSDID+V+FG W+  PLWTL + ++K  +A ++  KVLD+ATVPI+K+ D  TEV++DISFN+++G+++ANLIK + ++YP LP LVL+LKQ+LLQR+LNEV+TGGI SYSL LM VSF++L  ++   +S  NLG  LI F ELYGR+F+Y  TGIR +    +V K+E+ K+M   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV++YR+ I  ++ QK   E +
Sbjct:  125 KRKRD-NKASTYGFNRSLLLTDGAEDGYAGTPWKSRN--YSDGIVGLHEEIKDFYEYISPRPEEEQMRHEVVARIQRVIKDLWPNAEVCVFGSFSTGLYLPTSDIDLVVFGNWETLPLWTLEEALRKRKVADENSIKVLDKATVPIIKLMDSHTEVKVDISFNVQSGVKAANLIKDYKQQYPVLPYLVLVLKQFLLQRELNEVFTGGIGSYSLFLMAVSFLQLHCREDVSSSNPNLGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKSMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKEAFDYAYVILSHAVSP-IAKYYPNNKSESILGRIIRVTQEVVEYRDWISAQWGQKSSKEPV 489

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
Match: tent4a (terminal nucleotidyltransferase 4A [Source:ZFIN;Acc:ZDB-GENE-041021-1])

HSP 1 Score: 326.25 bits (835), Expect = 6.669e-103
Identity = 185/361 (51.25%), Postives = 248/361 (68.70%), Query Frame = 1

Query:  373 RKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQK 1437
            R++  NKAST+G +  L         S   PW  K + Y   +DGLHEEI+DFYN++ P  EE  MRQEVV R++ V+ + WP A V +FGSF T L LPTSDID+V+FGKW+  PL  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFN++ GI++A+ IK ++K+Y  LP L+ +LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R    N   NLG  LI F ELYGR+F+Y  TGIR +    ++ KE+I+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P +      ++ S LGRII++T EV+ YR  I +K+  +
Sbjct:    8 RRKSDNKASTYGINYLLSNWTNGNYESSGTPW--KTRKYSPGVDGLHEEIMDFYNFMSPRPEEATMRQEVVDRIESVIKELWPTADVQIFGSFSTGLFLPTSDIDLVVFGKWEKPPLQQLEQALRKHSVAEPYSIKVLDKATVPIIKLTDQETEVKVDISFNVETGIKAASFIKEYVKKYTVLPYLIFVLKQFLLQRDLNEVFTGGISSYSLILMVISFLQLHPRIDTRNPNMNLGILLIEFFELYGRHFNYLKTGIRIKNGGAYMAKEDIMKAMSNGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKEAFDYAYIILSHAVSPLARSYPNKDSDSTLGRIIKVTQEVIDYREWIIKKWGGR 366

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
Match: tent4a (terminal nucleotidyltransferase 4A [Source:ZFIN;Acc:ZDB-GENE-041021-1])

HSP 1 Score: 284.648 bits (727), Expect = 6.682e-89
Identity = 163/304 (53.62%), Postives = 217/304 (71.38%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLY--EGNTSILGRIIRITPEVMKYRNLIKEKFSQK 1437
            P  EE  MRQEVV R++ V+ + WP A V +FGSF T L LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFN++ GI++A+ IK ++K+Y  LP L+ +LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R    N   NLG  LI F ELYGR+F+Y  TGIR +    ++ KE+I+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  + + S LGRII++T EV+ YR  I +K + +
Sbjct:    3 PRPEEATMRQEVVDRIESVIKELWPTADVQIFGSFSTGLFLPTSDIDLVVFGKWEKPPLQQLEQALRKHSVAEPYSIKVLDKATVPIIKLTDQETEVKVDISFNVETGIKAASFIKEYVKKYTVLPYLIFVLKQFLLQRDLNEVFTGGISSYSLILMVISFLQLHPRIDTRNPNMNLGILLIEFFELYGRHFNYLKTGIRIKNGGAYMAKEDIMKAMSNGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKEAFDYAYIILSHAVSPL-ARSYPNKDSDSTLGRIIKVTQEVIDYREWIIKKHNSR 305

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
Match: tent2 (terminal nucleotidyltransferase 2 [Source:NCBI gene;Acc:553626])

HSP 1 Score: 55.8398 bits (133), Expect = 1.078e-7
Identity = 76/337 (22.55%), Postives = 139/337 (41.25%), Query Frame = 1

Query:  502 DGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLNDIIKKSGIAS---------DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI---------------------------------NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWS-SILCIEDPLNPVNDIGRSSYGALH---IKMAFDYAYNTLS-----RVILPQSAQLYEGNTS 1359
            D L ++IL+ +       ++ E ++   A L+  + K +P AKV + GS        +SD D+ +  + + P+    D +    +           +   L RA VPIVK  D+ + V  D++FN   GI++  L++++     ++  LVL++K++     +N+   G +SSY+L+LM + +++   + +                                  +Q +LG+  + FL  Y   F +    I        V     L       W    +C+E+P N  N   R+ +  +    IK AF  +Y  L        ILP+S Q+    T+
Sbjct:  160 DKLSQQILNLFFACEQQSDDLEKKESCRAALQTDIQKIFPCAKVFLGGSSLNGFGSRSSDADLCLVIE-EGPVNHRKDAVYVLSLVRKLLYKLSYIEKPQLIRAKVPIVKFRDRISGVEFDLNFNNTVGIRNTFLLRTYAFVEKRVRPLVLVIKKWANHHCINDASRGTLSSYTLVLMVLHYLQTLPEPVIPCLQRDYPTCFDPKMDIHLVPSGPSDIPAFVSRNQSSLGDLFLGFLRYYATVFKWDKQVI-------SVRMARTLPKSNCKEWKDKFICVEEPFNRTN-TARAVHERMKFEAIKAAFIESYRLLQLRKDLNFILPKSKQMARPQTA 487

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Match: TENT4B (terminal nucleotidyltransferase 4B [Source:NCBI gene;Acc:100491336])

HSP 1 Score: 347.436 bits (890), Expect = 5.702e-110
Identity = 227/491 (46.23%), Postives = 298/491 (60.69%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNL---HNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFI----------------------KRKREYNKASTFGYDIQLQFGMISTVNS--DMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQK 1437
            MD   +W QPE  GP+  +W + +          Q   NL   HN P      P HSA + +      N       Y  S T   N  + +Q++    E                           KRKR+ NKASTFG +  LQ    S+V    +  PW  K + Y + + GLHEEI+DFY Y+ P  EE++MR EVV R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A ++  KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A LIK FIK+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R    +   N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV+ YR  I + + QK
Sbjct:    1 MDPRIAWFQPEQLGPSNSLWMQIWETT-------QGLRNLYFNHNSP----ASPTHSASSSSSSICETN-----TMYRDSGTAQNNQSLGEQRDYIPIETTNNNNNQLLSQSPGAWGKGHDHINRNKRKRD-NKASTFGLNCLLQCSAGSSVVGLYNGTPW--KTRTYSEEVIGLHEEIMDFYKYMSPRPEEEKMRMEVVNRIENVIKELWPNADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADENSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVKAAQLIKDFIKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACSLDANYGVLLIEFFELYGRHFNYVKTGIRIKEGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKFYPNNETESILGRIIRVTQEVVTYREWISKHWGQK 471

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Match: tyms (thymidylate synthetase [Source:Xenbase;Acc:XB-GENE-1001385])

HSP 1 Score: 56.225 bits (134), Expect = 1.979e-7
Identity = 67/301 (22.26%), Postives = 124/301 (41.20%), Query Frame = 1

Query:  517 EILD-----FYNYIMPTVEEQEMRQEVVARLKEVVLKEWP-EAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLN---------DIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI----------------------------------------NSQENLGETLIMFLELYGRNFDY--FNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIG 1248
            EILD      Y+ + P   EQ+ R++++A L+  + KE+   +++ +FGS K       SD+D+ +  +       LN          ++KK     +   +  A VPIVK   KE+ V  DIS        +  ++ ++    P++  L   +K +  + D+ +   G +SSY+ ILM + F++ R   +                                         ++E++GE  + FL  Y   FD+  +   IR         ++++L   E    S  + IEDP +  +++G
Sbjct:  681 EILDRVCKRCYDELSPNSSEQQNREQILAYLERFIRKEFNNHSRLCLFGSSKNGFGFRDSDLDICMTLEGHENAKKLNCKEIIDGLAKVLKKHPGLKNILAITTAKVPIVKFEHKESGVEGDISLYNTLAQHNTRMLATYAAIDPRVKYLGYTVKFFAKRCDIGDASRGSLSSYAYILMVLYFLQQRNPPVIPVLQEIYDGQETPQRMVDGWNAFFFDNTEELRNRFPSLGKNRESVGELWLGFLRFYTEEFDFKEYVISIR---------QKKLLTTFEKQWTSKCIAIEDPFDLNHNLG 972

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Match: tyms (thymidylate synthetase [Source:Xenbase;Acc:XB-GENE-1001385])

HSP 1 Score: 56.225 bits (134), Expect = 2.011e-7
Identity = 67/301 (22.26%), Postives = 124/301 (41.20%), Query Frame = 1

Query:  517 EILD-----FYNYIMPTVEEQEMRQEVVARLKEVVLKEWP-EAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLN---------DIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI----------------------------------------NSQENLGETLIMFLELYGRNFDY--FNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIG 1248
            EILD      Y+ + P   EQ+ R++++A L+  + KE+   +++ +FGS K       SD+D+ +  +       LN          ++KK     +   +  A VPIVK   KE+ V  DIS        +  ++ ++    P++  L   +K +  + D+ +   G +SSY+ ILM + F++ R   +                                         ++E++GE  + FL  Y   FD+  +   IR         ++++L   E    S  + IEDP +  +++G
Sbjct:  681 EILDRVCKRCYDELSPNSSEQQNREQILAYLERFIRKEFNNHSRLCLFGSSKNGFGFRDSDLDICMTLEGHENAKKLNCKEIIDGLAKVLKKHPGLKNILAITTAKVPIVKFEHKESGVEGDISLYNTLAQHNTRMLATYAAIDPRVKYLGYTVKFFAKRCDIGDASRGSLSSYAYILMVLYFLQQRNPPVIPVLQEIYDGQETPQRMVDGWNAFFFDNTEELRNRFPSLGKNRESVGELWLGFLRFYTEEFDFKEYVISIR---------QKKLLTTFEKQWTSKCIAIEDPFDLNHNLG 972

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Match: tyms (thymidylate synthetase [Source:Xenbase;Acc:XB-GENE-1001385])

HSP 1 Score: 55.8398 bits (133), Expect = 2.249e-7
Identity = 67/301 (22.26%), Postives = 124/301 (41.20%), Query Frame = 1

Query:  517 EILD-----FYNYIMPTVEEQEMRQEVVARLKEVVLKEWP-EAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLN---------DIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI----------------------------------------NSQENLGETLIMFLELYGRNFDY--FNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIG 1248
            EILD      Y+ + P   EQ+ R++++A L+  + KE+   +++ +FGS K       SD+D+ +  +       LN          ++KK     +   +  A VPIVK   KE+ V  DIS        +  ++ ++    P++  L   +K +  + D+ +   G +SSY+ ILM + F++ R   +                                         ++E++GE  + FL  Y   FD+  +   IR         ++++L   E    S  + IEDP +  +++G
Sbjct:  664 EILDRVCKRCYDELSPNSSEQQNREQILAYLERFIRKEFNNHSRLCLFGSSKNGFGFRDSDLDICMTLEGHENAKKLNCKEIIDGLAKVLKKHPGLKNILAITTAKVPIVKFEHKESGVEGDISLYNTLAQHNTRMLATYAAIDPRVKYLGYTVKFFAKRCDIGDASRGSLSSYAYILMVLYFLQQRNPPVIPVLQEIYDGQETPQRMVDGWNAFFFDNTEELRNRFPSLGKNRESVGELWLGFLRFYTEEFDFKEYVISIR---------QKKLLTTFEKQWTSKCIAIEDPFDLNHNLG 955

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Match: tyms (thymidylate synthetase [Source:Xenbase;Acc:XB-GENE-1001385])

HSP 1 Score: 55.8398 bits (133), Expect = 2.302e-7
Identity = 67/301 (22.26%), Postives = 124/301 (41.20%), Query Frame = 1

Query:  517 EILD-----FYNYIMPTVEEQEMRQEVVARLKEVVLKEWP-EAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLN---------DIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI----------------------------------------NSQENLGETLIMFLELYGRNFDY--FNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIG 1248
            EILD      Y+ + P   EQ+ R++++A L+  + KE+   +++ +FGS K       SD+D+ +  +       LN          ++KK     +   +  A VPIVK   KE+ V  DIS        +  ++ ++    P++  L   +K +  + D+ +   G +SSY+ ILM + F++ R   +                                         ++E++GE  + FL  Y   FD+  +   IR         ++++L   E    S  + IEDP +  +++G
Sbjct:  660 EILDRVCKRCYDELSPNSSEQQNREQILAYLERFIRKEFNNHSRLCLFGSSKNGFGFRDSDLDICMTLEGHENAKKLNCKEIIDGLAKVLKKHPGLKNILAITTAKVPIVKFEHKESGVEGDISLYNTLAQHNTRMLATYAAIDPRVKYLGYTVKFFAKRCDIGDASRGSLSSYAYILMVLYFLQQRNPPVIPVLQEIYDGQETPQRMVDGWNAFFFDNTEELRNRFPSLGKNRESVGELWLGFLRFYTEEFDFKEYVISIR---------QKKLLTTFEKQWTSKCIAIEDPFDLNHNLG 951

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
Match: Tent4a (terminal nucleotidyltransferase 4A [Source:MGI Symbol;Acc:MGI:2682295])

HSP 1 Score: 343.969 bits (881), Expect = 2.783e-107
Identity = 196/393 (49.87%), Postives = 266/393 (67.68%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMF----------PWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKIS 1500
            +RKRE NKAST+G +  L     +T++              PW  K++ Y   + GLHEEI+DFYN++ P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      ++ S LGRII++T EV+ YR  IKEK+  +  P     +++N IK  E+I+
Sbjct:  180 RRKRE-NKASTYGLNYLLSGSRAATLSGGGGPGAQAARPGTPW--KSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWGSRILPSP---DLDNRIKIKERIT 566

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
Match: Tent4b (terminal nucleotidyltransferase 4B [Source:MGI Symbol;Acc:MGI:1917820])

HSP 1 Score: 332.413 bits (851), Expect = 4.008e-104
Identity = 198/379 (52.24%), Postives = 259/379 (68.34%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQL------------QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAST+G +  L            +      V S   PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV+R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  +  PE
Sbjct:  127 KRKRD-NKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGT-PWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPE 500

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Query:  370 KRKREYNKASTFGYDIQL------------QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAST+G +  L            +      V S   PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV+R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  +  PE
Sbjct:  127 KRKRD-NKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGT-PWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPE 500

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
Match: Tent4a (terminal nucleotidyltransferase 4A [Source:MGI Symbol;Acc:MGI:2682295])

HSP 1 Score: 302.753 bits (774), Expect = 3.115e-94
Identity = 170/324 (52.47%), Postives = 228/324 (70.37%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKIS 1500
            P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      ++ S LGRII++T EV+ YR  IKEK+  +  P     +++N IK  E+I+
Sbjct:    3 PCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWGSRILPSP---DLDNRIKIKERIT 323

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
Match: Tent4a (terminal nucleotidyltransferase 4A [Source:MGI Symbol;Acc:MGI:2682295])

HSP 1 Score: 302.753 bits (774), Expect = 3.115e-94
Identity = 170/324 (52.47%), Postives = 228/324 (70.37%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKIS 1500
            P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      ++ S LGRII++T EV+ YR  IKEK+  +  P     +++N IK  E+I+
Sbjct:    3 PCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWGSRILPSP---DLDNRIKIKERIT 323

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Match: sp|Q5XG87|PAPD7_HUMAN (Terminal nucleotidyltransferase 4A OS=Homo sapiens OX=9606 GN=TENT4A PE=1 SV=3)

HSP 1 Score: 341.273 bits (874), Expect = 1.368e-105
Identity = 196/402 (48.76%), Postives = 267/402 (66.42%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMF----------PWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSN 1527
            +RKRE NKAST+G +  L     + ++              PW  K++ Y   + GLHEEI+DFYN++ P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      +  S LGRII++T EV+ YR  IKEK+  K  P      +++ IK  E+I+  + ++  N
Sbjct:  167 RRKRE-NKASTYGLNYLLSGSRAAALSGGGGPGAQAPRPGTPW--KSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDAESTLGRIIKVTQEVIDYRRWIKEKWGSKAHPSP---GMDSRIKIKERIATCNGEQTQN 562

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Match: sp|Q68ED3|PAPD5_MOUSE (Terminal nucleotidyltransferase 4B OS=Mus musculus OX=10090 GN=Tent4b PE=1 SV=2)

HSP 1 Score: 333.183 bits (853), Expect = 5.718e-104
Identity = 198/379 (52.24%), Postives = 259/379 (68.34%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQL------------QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAST+G +  L            +      V S   PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV+R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  +  PE
Sbjct:   80 KRKRD-NKASTYGLNYSLLQPSGGRAAGGGRADGGGGVYSGT-PWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVSRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLQNRPE 453

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Match: sp|Q8NDF8|PAPD5_HUMAN (Terminal nucleotidyltransferase 4B OS=Homo sapiens OX=9606 GN=TENT4B PE=1 SV=2)

HSP 1 Score: 330.872 bits (847), Expect = 6.263e-104
Identity = 196/367 (53.41%), Postives = 253/367 (68.94%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQKRFPE 1449
            KRKR+ NKAS        +      V S   PW  +N  Y + + GLHEEI DFY Y+ P  EE++MR EVV R++ V+ + WP A V +FGSFKT L+LPTSDID+V+FGKW+N PLWTL + ++K  +A +   KVLD+ATVPI+K+TD  TEV++DISFN++NG+++A+LIK F K+YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R        N G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  + P  A+ Y  N   SILGRIIR+T EV  YR+ I +++  K  PE
Sbjct:   78 KRKRD-NKASGGRAAGGGRADGGGVVYSGT-PWKRRN--YNQGVVGLHEEISDFYEYMSPRPEEEKMRMEVVNRIESVIKELWPSADVQIFGSFKTGLYLPTSDIDLVVFGKWENLPLWTLEEALRKHKVADEDSVKVLDKATVPIIKLTDSFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSP-IAKYYPNNETESILGRIIRVTDEVATYRDWISKQWGLKNRPE 439

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Match: sp|Q6PB75|PAPD7_MOUSE (Terminal nucleotidyltransferase 4A OS=Mus musculus OX=10090 GN=Tent4a PE=2 SV=2)

HSP 1 Score: 302.753 bits (774), Expect = 2.179e-93
Identity = 170/324 (52.47%), Postives = 228/324 (70.37%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKIS 1500
            P  EE  MR+EVV R++ VV   WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFNM+ G+++A  IK+++K+Y  LP L+L+LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R     + ENLG  L+ F ELYGRNF+Y  TGIR +    ++ KEEI+K M   +  S+LCIEDPL P ND+GRSSYGA+ +K  FDYAY  LS  + P +      ++ S LGRII++T EV+ YR  IKEK+  +  P     +++N IK  E+I+
Sbjct:    3 PCPEEAAMRREVVKRIETVVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQALRKHNVAEPCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHPRIDARRADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEEIMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSESTLGRIIKVTQEVIDYRRWIKEKWGSRILPSP---DLDNRIKIKERIT 323

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Match: sp|Q7KVS9|TRF41_DROME (Non-canonical poly(A) RNA polymerase protein Trf4-1 OS=Drosophila melanogaster OX=7227 GN=Trf4-1 PE=1 SV=1)

HSP 1 Score: 310.071 bits (793), Expect = 5.045e-92
Identity = 175/358 (48.88%), Postives = 239/358 (66.76%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI-NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKF 1428
            ++KR  NKA    Y +     MI+    +  PW   +  Y + + GLHEEI  FY Y++PT  E  +R EVV R++ VV   WP+A V++FGSF+T L LPTSDID+V+ G W+  PL TL   +   GIA     +VLD+A+VPI+K+TD+ET+V++DISFNM++G+QSA LIK F ++YP L +LVL+LKQ+LL RDLNEV+TGGISSYSLILMC+SF+++  + I +   NLG  L+ F ELYGR F+Y   GI  +    ++PK+E+ ++M   H  S+LCIEDPL P NDIGRSSYG   ++ AF  AY  L+  + P +    +    SILGRII IT +V+ YR  I+E F
Sbjct:  227 RKKRPENKAGGAHYYMNNHMEMIAKYKGE--PWRKPDYPYGEGVIGLHEEIEHFYQYVLPTPCEHAIRNEVVKRIEAVVHSIWPQAVVEIFGSFRTGLFLPTSDIDLVVLGLWEKLPLRTLEFELVSRGIAEACTVRVLDKASVPIIKLTDRETQVKVDISFNMQSGVQSAELIKKFKRDYPVLEKLVLVLKQFLLLRDLNEVFTGGISSYSLILMCISFLQMHPRGIYHDTANLGVLLLEFFELYGRRFNYMKIGISIKNGGRYMPKDELQRDMVDGHRPSLLCIEDPLTPGNDIGRSSYGVFQVQQAFKCAYRVLALAVSPLNLLGIDPRVNSILGRIIHITDDVIDYREWIRENF 582

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Match: T1J4Z7 (Uncharacterized protein OS=Strigamia maritima OX=126957 PE=4 SV=1)

HSP 1 Score: 377.481 bits (968), Expect = 1.970e-118
Identity = 230/465 (49.46%), Postives = 301/465 (64.73%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSA--TDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGY----DIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAK--KINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKF 1428
            MD N  W QPE  GPAQK+WS+ +      + ++    N  N  Y    LP+H     NV +       ++E  L SA   +  NC          N      KRKRE N+AST+G     ++ L++G I        PW    K Y   + GLH+EI DFY Y+ P+ EE  MR +VV R+ +VV++ WP+AKV++FGSFKT L+LPTSDID+V+FG WD+ PL TL   +    IA     KVLD+A+VPIVK+TD +T+V++DISFNM NG+ SA LIK+F KE+P LP+LVL+LKQ+LLQRDLNEVWTGGISSYSLIL+ VSF++L  K    N+  NLG  LI F ELYGR+F+Y  TGIR +    ++ KEE+ K+M   H  S+LCIEDPLN  NDIGRSSYGALH+K AFDYA+  L + ++P++ +L +   SILGRI+RIT EV+ YR  I+E F
Sbjct:    1 MDPNIGWYQPEQQGPAQKLWSRLWE---TQQRLQNMDLNNANNDY----LPLH-----NVTN-------QVEACLRSARQQNSNNC--------IGNLYYNRTKRKRE-NRASTYGLNENSEMILEYGGI--------PWRNPAKPYSPGIVGLHQEIEDFYQYMSPSPEEHHMRDDVVKRITQVVIELWPQAKVEIFGSFKTGLYLPTSDIDLVVFGTWDSLPLRTLEKALLDYNIADPMTIKVLDKASVPIVKLTDLKTDVKVDISFNMNNGVGSAKLIKTFKKEFPALPKLVLVLKQFLLQRDLNEVWTGGISSYSLILLTVSFLQLHPKHDATNADANLGALLIEFFELYGRHFNYLKTGIRVKNGGAYIAKEEVQKDMVDGHRPSLLCIEDPLNAGNDIGRSSYGALHVKQAFDYAFVILCQAVVPRTPRLADLKFSILGRIVRITDEVVDYRRWIRENF 429

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Match: V3ZFX5 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_134093 PE=4 SV=1)

HSP 1 Score: 370.548 bits (950), Expect = 8.851e-118
Identity = 222/492 (45.12%), Postives = 312/492 (63.41%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAY-LDVFIDKI-IKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIA--SDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKD 1521
            MD   +W  PE  GPA + W++ +   + +DK+ +  S  N    P+  N    +  +  N  + +HN                N     Q            KRKRE N+AST+G +      ++   +  + PW VK K Y+ +L GLH+EI DF+ Y+ P  EE++MR EVV+R+++V+   WP+AK+++FGSF+T L+LPTSDID+V+FGKW   PLW+L D I+K  IA   D KVLD+A+VPIVK+TDKET+V++DISFNM +G++SA LI  +++E+P L  LVL+LK +LLQRDLNEV+TGGISSYSLILMC++F++L  R    + + NLG  LI F EL+GRNF+Y+ T IR +G   ++PKEEI KNME  +  S+LCIEDPL P NDIGRSSYGA+ ++ AF+YA+  L   + PQ+  L +G  S+L RIIR+T EV++YR++I +K+  K           NT  T    S N+ K D
Sbjct:    1 MDPKIAWFTPEQLGPAHEFWARNWEAQLGVDKMYLNNSDHNRDFLPFNDN----YRHYNHNRNNGYHN---------------SNNHYAPQ------------KRKRE-NRASTYGLNHSADKHLLRE-HGGLTPWLVKGKTYRPDLSGLHDEIKDFFGYMSPREEERQMRNEVVSRIRQVMEDLWPDAKMEIFGSFRTGLYLPTSDIDLVVFGKWKTLPLWSLRDEIRKREIAYPEDIKVLDKASVPIVKLTDKETDVQVDISFNMMSGVKSAGLITEYMEEFPNLKYLVLVLKHFLLQRDLNEVFTGGISSYSLILMCINFLQLHPRIDARSPEANLGVLLIEFFELFGRNFNYWKTAIRIKGGGAYLPKEEIAKNMESGYRPSLLCIEDPLMPKNDIGRSSYGAMQVRHAFEYAFTILQYAVAPQNQCLMKG--SVLSRIIRVTNEVVEYRDIICQKYRCK-----------NTDSTDSDESSNEEKND 446

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Match: R7US80 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_115913 PE=4 SV=1)

HSP 1 Score: 367.081 bits (941), Expect = 3.653e-117
Identity = 210/399 (52.63%), Postives = 280/399 (70.18%), Query Frame = 1

Query:  325 NDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQK-NLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQ 1503
            N++++ + N+   F+ RKRE NKASTFG +       +   N  M PW   +KVY    + GLH+EI+DFY Y+ P  EE  MR++VV R+  V+   WP AKV++FGSF+T L+LPTSDID+V+FGKW+N PL+TL   + K GI  ++  KVLD+A+VPIVK+TDK+TEV++DISFNM NG++SANLI  ++++ P LP LVL+LKQ+LLQRDLNEV+TGGISSYSLIL+ VSF++L  R   + S  NLG  LI F ELYGR+F+Y  TGIR +    +VPK++I+K+ME  H  S+LCIEDPLNP NDIGRSSYGAL +K AF+YA+  L   + PQ A L+    SILGRI+R+T EV++YR  I++ F        I I + +  K S   SQ
Sbjct:   27 NNKQQHYQNQ--HFLNRKRE-NKASTFGLNHSSCVQRLR--NRGMTPWQAHDKVYASPGVIGLHQEIMDFYEYMSPQPEEHYMREDVVQRISAVIQGLWPCAKVEIFGSFRTHLYLPTSDIDLVVFGKWENIPLFTLEKELLKMGICEEAQIKVLDKASVPIVKLTDKKTEVKVDISFNMNNGVRSANLIMDYMRDMPTLPYLVLVLKQFLLQRDLNEVFTGGISSYSLILLTVSFLQLHPRLDAMRSDANLGVLLIEFFELYGRHFNYIKTGIRIKNGGSYVPKDDIIKDMENGHRPSLLCIEDPLNPGNDIGRSSYGALTVKQAFEYAFLVLRDAVSPQYAHLHSPKDSILGRIVRVTDEVVEYRKWIRQSFP-------ISIEVYDRHKASCPFSQ 413

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Match: A0A1S3I2A4 (non-canonical poly(A) RNA polymerase PAPD5-like OS=Lingula unguis OX=7574 GN=LOC106160359 PE=4 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 2.421e-113
Identity = 210/463 (45.36%), Postives = 298/463 (64.36%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEV--LEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQ 1434
            MD    W+ PE  GPA ++W++    ++   +IK  +  L+N               PN++        + +EY+    +  N    D      N +   +F  RK++ NKASTFG +      ++   N  + PW  + + Y   + GLHEEI+D Y Y++P  EE  MRQ+VV R+++V+   WP+AKV++FGSF+T  +LPTSDID+V+ GKWD+ PLWTL   + +  I    + +VLD+A+VPIVK+TD +T+V++DISFNM NG++SA LI ++  +YP L  LV++LKQ+LLQRDLNEV+TGGISSY LILM VSF++L  R    +   NLG  LI F ELYGR+F+Y  TGIR +G   +VPKE+I K ME  +  S+LCIEDPLNP NDIGRSSYGAL+++ AF+YAY TLS   L  ++ +++G  S+L RIIR+T EV++YR  IKE + +
Sbjct:    1 MDPRIGWSPPEQLGPAHQLWTR----LWETHLIKMENLYLNN-------------ANPNLEQ-------KTQEYIPLEFNTNNYDQRDHSSSRTNNIKYQDFRTRKKKDNKASTFGLNHSSNTQLLD--NGHLTPWIPRGRNYSPGVIGLHEEIIDLYQYMLPRREEHYMRQDVVRRIEKVIKDLWPQAKVEIFGSFRTSFYLPTSDIDLVVLGKWDSLPLWTLEKELLEKNITDKMNIRVLDKASVPIVKLTDIKTDVKVDISFNMVNGVKSAKLIMNYRDQYPTLQYLVMVLKQFLLQRDLNEVFTGGISSYCLILMVVSFLQLHPRIDATSEDANLGVLLIEFFELYGRHFNYLKTGIRIKGGGAYVPKEQIQKEMENGYRPSLLCIEDPLNPGNDIGRSSYGALNVRNAFEYAYLTLSNAALSANSDVFKGQQSLLSRIIRVTDEVVEYRQWIKETYGK 437

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Match: A0A0C9R9K8 (Papd5_1 protein OS=Fopius arisanus OX=64838 GN=Papd5_1 PE=4 SV=1)

HSP 1 Score: 359.377 bits (921), Expect = 3.796e-112
Identity = 220/463 (47.52%), Postives = 292/463 (63.07%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAY-LDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFG--YDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEG-NTSILGRIIRITPEVMKYRNLIKEKF 1428
            MD    W QPE  GPA+ +W   +  +  ID I+   + N          + +H   T   K      PI      V   +D+   IN Q     N      +RK + N+AST G  Y+ +   G+         PW   NK Y K + GLHEEI DFY Y+ P+ EE  +R  VV R+++V+   WP++KV+VFGSF+T L+LPTSDID+V+ G+W N PL TL   +    IA  S  KVLD+A+VPIVK+TDKETE+++DISFNM NG++SA LIK + K+YP L +LV++LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R    N++ NLG  LI FLELYGR F+Y  TGIR +    ++ KEE+ ++M   H  SILCIEDPL P NDIGRSSYGAL+++ AFDYAY+ LS  + P +  + +    SILGRI+R+T EV++YR  IKE F
Sbjct:    1 MDPTIGWYQPEQCGPAKDLWCHIWEAEKGID-ILTLKNDNC--------AVALHGVTTMTTKFNHDYIPIDNSNNRV---NDDRTVINRQVHNSCNNYYNPSRRKSD-NRASTHGMNYNEEALVGLYGGC-----PWRTSNKQYSKGVIGLHEEIQDFYGYMCPSREEHCLRLRVVKRIEQVIYDLWPDSKVEVFGSFRTGLYLPTSDIDLVVIGRWSNLPLRTLESALLDQNIAEPSSIKVLDKASVPIVKLTDKETEIKVDISFNMNNGVKSAELIKKYKKQYPVLDRLVMVLKQFLLQRDLNEVFTGGISSYSLILMTISFLQLHPRQNAFNAEANLGVLLIEFLELYGRKFNYLKTGIRIKDGGTYISKEEVQRDMIDGHRPSILCIEDPLTPGNDIGRSSYGALYVQNAFDYAYSVLSEAVSPLNVLVNDAYKLSILGRIVRVTDEVVEYRKWIKETF 445

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
Match: tent4a (terminal nucleotidyltransferase 4A [Source:NCBI gene;Acc:103038688])

HSP 1 Score: 330.102 bits (845), Expect = 8.689e-102
Identity = 183/371 (49.33%), Postives = 254/371 (68.46%), Query Frame = 1

Query:  349 NEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAK---KINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQKR 1440
            N +     R++  NKAST+G++  L         +   PW  K + Y   ++GLHEEI+DFYN++ P  EE  MRQEVV R++ V+ ++WP A V +FGSF T L+LPTSDID+V+FGKW+  PL  L   ++K+ +A     KVLD+ATVPI+K+TD+ETEV++DISFN++ G+++A  IK ++K+Y  LP L+ +LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  +   +I    NLG  LI F ELYGRNF+Y  TGIR +    ++ KE+I+K M   +  S+LCIEDPL P ND+GRSSYGA+H+K  FDYAY  L   + P +      ++ S LGRII++T EV+ YR  I +K+  K+
Sbjct:  279 NHLHHHPGRRKSDNKASTYGFNCLLSDCTNGNHVNSGTPW--KTRSYSPGVNGLHEEIIDFYNFMSPRPEEATMRQEVVDRIESVIKEQWPSADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQQLEQALRKNNVAEPYSIKVLDKATVPIIKLTDQETEVKVDISFNVETGVKAARFIKDYVKKYTVLPYLIFVLKQFLLQRDLNEVFTGGISSYSLILMVISFLQLHPRFDPRI-PNTNLGVLLIEFFELYGRNFNYLQTGIRIKNGGAYMAKEDIMKAMSNGYRPSMLCIEDPLLPGNDVGRSSYGAMHVKHVFDYAYIVLGNAVSPLANSYPNKDSDSTLGRIIKVTQEVIDYREWIVQKWGSKQ 646

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
Match: tent4b (terminal nucleotidyltransferase 4B [Source:ZFIN;Acc:ZDB-GENE-041021-2])

HSP 1 Score: 319.316 bits (817), Expect = 2.995e-99
Identity = 191/368 (51.90%), Postives = 249/368 (67.66%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQLQFGMISTVNSDMF-------PWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT--SILGRIIRITPEVMKYRNLIKEKFS 1431
            KRKRE NKASTFG++  L          +         PW  +N  Y + + GLHEEI DFY Y+ P  EE+ MR EVV R++ V+   W    V VFGSF T L+LPTSDID+V+FG W+  PLWTL + ++K  +A ++  KVLD+ATVPI+K+TD  TEV++DISFN+ +G+++ANLIK F K++P LP LVL+LKQ+LLQR+LNEV+TGGI SYSL LM VSF++L  R    +   N+G  LI F ELYGR+F+Y  TGIR +    +V KEE+LK M   +  S+L IEDPL P ND+GRSSYGA+ +K AFDYAY  LS  +    A+ Y  N   SILGRIIR+T EV +YR+ I E++ 
Sbjct:  131 KRKRE-NKASTFGFNRSLILHGCGPEQEEEAAAAYTGTPWKKRN--YSEGIVGLHEEIKDFYEYMSPRPEEERMRFEVVDRIERVIKDLW----VQVFGSFSTGLYLPTSDIDLVVFGNWETLPLWTLEEALRKRNVADENSVKVLDKATVPIIKLTDSHTEVKVDISFNVCSGVKAANLIKDFKKKFPVLPYLVLVLKQFLLQRELNEVFTGGIGSYSLFLMAVSFLQLHYREDACSPNSNMGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKEEVLKGMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAV-SSIAKYYPNNKSESILGRIIRVTREVAEYRDWISEQWG 490

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
Match: TENT4A (non-canonical poly(A) RNA polymerase PAPD7-like [Source:NCBI gene;Acc:103036307])

HSP 1 Score: 314.309 bits (804), Expect = 1.608e-96
Identity = 180/366 (49.18%), Postives = 250/366 (68.31%), Query Frame = 1

Query:  373 RKREYNKASTFGYDIQLQFGMISTVNSDMF----PWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIKEKFSQK 1437
            RK+  NKAST+G++      ++S  N++ F    PW  K + Y   ++GLHEEI+DFY+++ P  +E+ MR++VV R++ V+   WP A V +FGSF   L+LPTSDID+V+FGKW+ P L  L+  +++  +A     K+LD+ATVPI+K+TD+ETEV++DISFN++ G+++A  IK  +K+Y  LP L+ +LKQ+LLQRDLNEV+TGGISSY LILM +SF++L  R     +  NLG  LI F ELYGRNF+Y  TGIR +    ++ KEEI K M   H  S+LCIEDP  P ND+GRSSYGA+H+K  FDYAY  LS  + P  A+ Y      S LGRI+R+T EV+ YR  I +K+  +
Sbjct:  185 RKKGDNKASTYGFNY-----LLSHSNTNHFCSGTPW--KKRRYGPGVNGLHEEIVDFYDFMSPRPQEEAMRRDVVNRIETVIKNLWPTANVQIFGSFSYGLYLPTSDIDLVVFGKWERPPLQQLDQALRQQNLAEPFSIKILDKATVPIIKLTDRETEVKVDISFNVETGVKAARFIKDHLKKYSVLPYLIFVLKQFLLQRDLNEVFTGGISSYCLILMAISFLQLHPRIDCRGTNINLGILLIEFFELYGRNFNYLKTGIRVKNGGAYLAKEEISKGMTNGHRPSMLCIEDPNLPGNDVGRSSYGAMHVKQVFDYAYIVLSHAVSPL-ARSYPNKEMDSTLGRILRLTQEVIDYREWIMQKWGDR 542

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
Match: TUT4 (terminal uridylyltransferase 4 [Source:NCBI gene;Acc:103031850])

HSP 1 Score: 60.077 bits (144), Expect = 6.727e-9
Identity = 58/205 (28.29%), Postives = 94/205 (45.85%), Query Frame = 1

Query:  556 EEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSD--IDVVIFGKWDNP--LWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFD------YFNTGIRTEG 1140
            EE + RQ V+ R+++++ K  P   + ++GS  T     TSD  IDV        P  L  + DI+KKS   S+ +    A VP+V   D  + +   +S        + N + +  +  P+L  LVL  + +     ++    GGI SYS  LM + F++ R + I         L ++L  +   FD      Y  TG++TEG
Sbjct:  276 EEFQQRQGVLKRMQQIIQKHLPTCSLRLYGSCLTRFAFKTSDLNIDVAYPPNMTQPDVLIQVLDILKKSAEFSEVESDFHAKVPVVFCRDAASGLPCKVSAGNDVACLTTNHLAALARLEPRLVPLVLAFRYWAKLCHVDCQAEGGIPSYSFSLMVIFFLQQRKQPI---------LPVYLGCWIEGFDVKRVDEYHLTGVQTEG 471

HSP 2 Score: 56.225 bits (134), Expect = 1.150e-7
Identity = 49/187 (26.20%), Postives = 92/187 (49.20%), Query Frame = 1

Query:  517 EILD-----FYNYIMPTVEEQEMRQEVVARLKEVVLKEW-PEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLN---------DIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLR 1032
            EILD      Y+ + PT+ EQ+ R++++  L+  + KE+  +A++ +FGS K       SD+D+ +  +  +    LN          I+KK     +   +  A VPIVK   K++ +  DIS        +  ++ ++    P++  L   +K +  + D+ +   G +SSY+ ILM + F++ R
Sbjct:  798 EILDNLCKLCYHELSPTLGEQQKREQILCSLERFIRKEYNDKAQLCLFGSSKNGFGFRDSDLDICMTLEGHDTAEKLNCKEIIEGLAKILKKHTGLRNILPITTAKVPIVKFEHKQSGLEGDISLYNTLAQHNTRMLATYAALDPRVQLLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQQR 984

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007887.1 (pep scaffold:Pmarinus_7.0:GL478966:13667:20299:-1 gene:ENSPMAG00000007125.1 transcript:ENSPMAT00000007887.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 134.035 bits (336), Expect = 2.526e-36
Identity = 71/163 (43.56%), Postives = 98/163 (60.12%), Query Frame = 1

Query:  961 NEVWTGGISSYSLILMCVSF---MKLRAK--KINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFS 1431
            NE +TGG+SSY L+++ VSF   M+L A     +   +LG  LI F ELYGRNF+Y   GIR +    +V K E  K +      S L +EDP+ P  D+GRSSYGA+  + AFDYAY  LSR + PQ+      +  S LGRI+++T EV +YR  I++ + 
Sbjct:   35 NEPYTGGVSSYLLVMLVVSFLQPMQLHADIDGRSGDGDLGVLLIEFFELYGRNFNYLKAGIRIKDGGSYVAKAEAQKELVEGFGPSFLFVEDPVVPGQDLGRSSYGAMQARQAFDYAYTVLSRAVCPQAKHYPNRDLDSTLGRIVKVTREVTEYREWIQQTWG 197

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Yeast
Match: PAP2 (Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia [Source:SGD;Acc:S000005475])

HSP 1 Score: 171.785 bits (434), Expect = 1.833e-46
Identity = 120/344 (34.88%), Postives = 198/344 (57.56%), Query Frame = 1

Query:  445 VNSDMFPWNV-KNKVYQKNL-DGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWD-----NPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAK----KINSQENLGETLIMFLELYGRNFDYFNTGI-RTEGDSCHVPKEEILKNMEGNHWSSI--------LCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLS-RVILPQSAQLYEG-NTSILGRIIRITPEVMKYRN 1410
            +N+D +PW +  +   QK + D L  EI DF  YI P+ EE E+R + ++ ++E V + WP+A + VFGS+ T+L+LP SDID V+  +       N L++L   +KK  +A++ +V+ +A VPI+K  +  + + ID+SF   NGI++A LI+ ++ + P L +LVL++KQ+L  R LN V TGG+  +S+I +  SF+ +  +    +I+ ++NLG  LI F ELYG+NF Y +  +  ++G   + PK         + WS+I        L I+DP +  N+I R S+    IK AF  A++ L+ R     SA   +    SILG +I+   +   +++
Sbjct:  157 LNTD-YPWILNHDHSKQKEISDWLTFEIKDFVAYISPSREEIEIRNQTISTIREAVKQLWPDADLHVFGSYSTDLYLPGSDIDCVVTSELGGKESRNNLYSLASHLKKKNLATEVEVVAKARVPIIKFVEPHSGIHIDVSFERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGGLGGFSIICLVFSFLHMHPRIITNEIDPKDNLGVLLIEFFELYGKNFGYDDVALGSSDGYPVYFPK---------STWSAIQPIKNPFSLAIQDPGDESNNISRGSFNIRDIKKAFAGAFDLLTNRCFELHSATFKDRLGKSILGNVIKYRGKARDFKD 490

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Yeast
Match: TRF5 (Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of the TRAMP complex; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; overlapping but non-redundant functions with Pap2p [Source:SGD;Acc:S000005243])

HSP 1 Score: 163.696 bits (413), Expect = 3.096e-43
Identity = 125/368 (33.97%), Postives = 204/368 (55.43%), Query Frame = 1

Query:  460 FPWNVKNKVYQKN---LDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVI----FGKWD-NPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFM----KLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIR-TEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT--SILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTI--KTSEKISQNDV 1512
            +PW ++N  + K     D L  EI DF +YI P+  E + R   + +L+  V + W +A + VFGSF T+L+LP SDID V+      K D N ++ L   +K  G+A   +V+ +  VPI+K  + ++++ ID+SF   NG+++A LI+ ++++ P L +LVL++KQ+L  R LN V TGG+  +++I +  SF+    ++++  I+  +NLG  LI F ELYG+NF Y +  I  ++G + ++PK    + +E +     L I+DP +P N+I R S+    IK AF  A+  L       ++  ++     SILG +I       KYR   K  F+ +R   Q +  IEN    K   +I Q D+
Sbjct:  158 YPW-IRNHCHSKQRRIADWLTSEIKDFVHYISPSKNEIKCRNRTIDKLRRAVKELWSDADLHVFGSFATDLYLPGSDIDCVVNSRNRDKEDRNYIYELARHLKNKGLAIRMEVIVKTRVPIIKFIEPQSQLHIDVSFERTNGLEAAKLIREWLRDSPGLRELVLIIKQFLHSRRLNNVHTGGLGGFTVICLVYSFLNMHPRIKSNDIDVLDNLGVLLIDFFELYGKNFGYDDVAISISDGYASYIPK-SCWRTLEPSRSKFSLAIQDPGDPNNNISRGSFNMKDIKKAFAGAFELLVNKCWELNSATFKDRVGKSILGNVI-------KYRGQ-KRDFNDERDLVQNKAIIENERYHKRRTRIVQEDL 515

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Nematostella
Match: EDO40179 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S822])

HSP 1 Score: 228.794 bits (582), Expect = 1.357e-69
Identity = 139/300 (46.33%), Postives = 194/300 (64.67%), Query Frame = 1

Query:  547 PTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWT---GGISSYSLILMCV--SFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVI-LPQSAQLYEGNTSILGRIIRITPEVMKYRNLIK 1419
            P   E+ MR EVV R+ EV+++ WP AKV+V+GSFKT L LPTSDID+V+FGKW+  PLWTL   ++ + IA  S  KVLD+A+VPI+K+TDK+T+V++DISFN+  G  +A  +K  ++ +P LP LVL+LKQ+L+ RDLNEV+      +  +  IL CV  S    R    +   NLG  LI F ELYG NF+Y NTGI       +  K+E+L ++     +S+LCIEDP  P N IG+SSY  + +K AF+YAY  LS+ +  P          S+L RI+R+T E ++YRN ++
Sbjct:    3 PRKCEEAMRWEVVGRVHEVIVRLWPTAKVEVYGSFKTALFLPTSDIDLVVFGKWERLPLWTLEKALQANQIADPSSIKVLDKASVPIIKLTDKKTQVKVDISFNVLAGPTAAKFVKENMELFPCLPPLVLVLKQFLVLRDLNEVFRIFKAKLDIFDFILPCVFISQHHPRGDGCSLDHNLGVLLIEFFELYGNNFNYVNTGISVRDGGSYFNKQEVLNDVGEGFNTSLLCIEDPFTPGNYIGKSSYAFMQVKQAFNYAYLVLSKAVNSPNPTIDGVSKHSLLSRIVRVTKEAVEYRNFVE 302

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
Match: tent4a (terminal nucleotidyltransferase 4A [Source:NCBI gene;Acc:101162261])

HSP 1 Score: 332.798 bits (852), Expect = 3.339e-103
Identity = 183/361 (50.69%), Postives = 245/361 (67.87%), Query Frame = 1

Query:  373 RKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNP-LWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNT-SILGRIIRITPEVMKYRNLIKEKFSQK 1437
            R++  NKAST+G    L         S M PW  K   Y   + GLHEE++DFY Y+ P  EE  MR+EVV R++ ++ ++WP A V +FGSF T L+LPTSDID+V+FGKW+ P L  L   ++K  +A     KVLD+ATVPI+K+TD+ETEV++DISFN++ G+++A+ IK ++K+YP LP L+ +LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L  R    N  ENLG  LI F ELYGR+F+Y  TGIR      ++ KEE++K M   +  S+LCIEDPL P ND+GR SYGA+ +K  FDYAY  LS  + P +      +  S LGRIIR+T EV+ YR  I +K+  K
Sbjct:  199 RRKSDNKASTYGMTYLLSICTHGGHASTMTPW--KTMTYSAGIRGLHEEVMDFYKYMSPRPEEAAMRKEVVKRIETIIKEQWPSADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQELEQALRKHNVAEPFSIKVLDKATVPIIKLTDQETEVKVDISFNVETGVKAASFIKDYVKKYPVLPYLIFVLKQFLLQRDLNEVFTGGISSYSLILMVISFLQLHPRINARNPNENLGMLLIEFFELYGRHFNYLKTGIRIRNGGAYMAKEEMMKAMTNGYRPSMLCIEDPLLPGNDVGRGSYGAMQVKQVFDYAYAILSHAVSPLARSYPNKDCESTLGRIIRLTQEVIDYREWIIKKWGGK 557

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
Match: tent4b (terminal nucleotidyltransferase 4B [Source:NCBI gene;Acc:101157441])

HSP 1 Score: 324.324 bits (830), Expect = 4.384e-101
Identity = 193/359 (53.76%), Postives = 250/359 (69.64%), Query Frame = 1

Query:  370 KRKREYNKASTFGYDIQL--QFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIASDS--KVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKL--RAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGN--TSILGRIIRITPEVMKYRNLIK 1419
            KRKRE NKAST+G++  L   F           PW  +N  Y   + GLHEEI DFY+YI P  EE++MR EVV R+K V+   WP A+V VFGSF T L+LPTSDID+V+FGKW+  PLWTL + ++K  +A  S  KVLD+ATVPI+K+TD  TEV++DISFN+++G+++A LIK F ++YP LP LVL+LKQ+LLQRDLNEV+TGGI SYSL LM VSF++L  R    +   N+G  LI F ELYGR+F+Y  TGIR +    +V K+E+ KNM   +  S+L IEDPL P ND+GRSSYGA+ +K AF+YA+  L   +  Q A+ Y  N   SILGRIIR+T EV +YR  I+
Sbjct:  141 KRKRE-NKASTYGFNSSLLNNFNSGGHEAYTGTPWKTRN--YADTVVGLHEEIKDFYDYISPRPEEEKMRLEVVDRIKGVIHDLWPSAEVQVFGSFSTGLYLPTSDIDLVVFGKWETLPLWTLEEALRKRNVADKSAIKVLDKATVPIIKLTDSVTEVKVDISFNVESGVKAARLIKEFKEKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLMAVSFLQLHFREDVCSPNINIGVLLIEFFELYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMMDGYRPSMLYIEDPLQPDNDVGRSSYGAMQVKQAFEYAFVVLHHAV-SQIAKCYPNNESESILGRIIRVTKEVDEYREWIR 495

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
Match: ENSORLT00000036168.1 (non-canonical poly(A) RNA polymerase PAPD7 [Source:NCBI gene;Acc:101163355])

HSP 1 Score: 302.368 bits (773), Expect = 9.652e-92
Identity = 173/366 (47.27%), Postives = 257/366 (70.22%), Query Frame = 1

Query:  373 RKREYNKASTF-GYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDN-PLWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKINSQE---NLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLY--EGNTSILGRIIRITPEVMKYRNLIKEKFSQKRF 1443
            R+R  N+A TF G +  +  G ++  ++D      K++ Y   ++GLHEEILDF++++ P  EE+ MR++VV +++ V+   WP A+V++FGSF T L+LPTSDID+V+FGKW++ PL  L   +KK  +A     KVLD+A+VPI+K+TD+E++V++DISFN++  +++A  IKS++K+Y  LP L+ +LKQ+LLQRDLNEV+TGGISSYSLILM +SF++L   +I+++    NLG  LI F ELYG +F+Y  TGIR +    ++ KEE+LK M   +  S+LCIEDP+ P ND+ R+SYG L +K  FD+AY  LS  + P  A+ Y  +   SILGRII+I+PEV+ YR    +K+  K++
Sbjct:  172 RRRPLNRAYTFHGINPLVPCG-VNGHHADASSSLWKSRRYSPGINGLHEEILDFFHFMSPKPEEEAMRRDVVNKIEGVIKDLWPTARVEIFGSFSTGLYLPTSDIDLVVFGKWEHPPLQELEQALKKCNVAGPYPVKVLDKASVPIIKLTDQESKVKVDISFNVETAVKAAQFIKSYLKKYAVLPPLIFVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLHP-RIDTRRTNINLGILLIEFFELYGHDFNYMKTGIRVKNGGAYLSKEEMLKTMGNGNRPSVLCIEDPVQPGNDVCRNSYGVLQVKQVFDFAYMVLSHGVSPL-ARGYPIKEYDSILGRIIKISPEVLAYREWTIKKWGAKQY 534

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
Match: tent2 (terminal nucleotidyltransferase 2 [Source:NCBI gene;Acc:101155937])

HSP 1 Score: 68.5514 bits (166), Expect = 9.485e-12
Identity = 98/449 (21.83%), Postives = 179/449 (39.87%), Query Frame = 1

Query:   79 YSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNEL----PIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLH--EEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDV--VIFG-KWDNPLWTLNDIIKKSGIAS--DSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKI---------------------------------NSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHW-SSILCIEDPLNPVNDIGRSSYGALHIKMAFD 1290
            Y W+ P +  PA     K  L+       ++   N  N PYF+  L    P H+  +P +   W  PP RL    V+A                                ST       +FG    +++       + +   K+ + L    ++++ +        + E ++   ARL+E +   +  A++ + GS    L   +SD D+  VI G K  +PL  L+ + K     S  +   L RA VPI+K  +K +++  D++ N   GI++  L++S+    P++  ++L++K++     +N+   G +SSY+L+LM + +++     +                                  +Q +LGE L+ FL  Y   F +    I    ++   PK           W    +C+E+P    N++ R    A+H K+ FD
Sbjct:   49 YVWSPPPYFAPAMVPPQKPALNY------RRKRPNADNTPYFEKRLRLDPPSHATASPVLN--WAPPPSRLPHQAVAAL-------------------------------STPALSCLDRFGPSRHISTP-----PQGQTVPKSFNSLQLSRQMVELFEACQQQSIDLERKEVFRARLQEDIQSIFSVARLYLTGSSMNGLGCRSSDADLCLVITGNKKPDPLSVLSRLRKLFRTLSYVEGTCLIRAKVPILKFKEKGSDLEFDLNINNTVGIRNTFLLRSYAHADPRVRPMILVVKKWACHHQINDASKGTLSSYTLVLMVLHYLQTVRDPVLPSLQRDHPDCFSPCMEIDMVPEGSTHVPPYISRNQSSLGELLLGFLRYYASEFSWDKQVISVR-EATAFPK------TYAQEWRKKFICVEEPFE-RNNVAR----AVHEKLKFD 441

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Match: SMESG000017326.1 (SMESG000017326.1)

HSP 1 Score: 1100.89 bits (2846), Expect = 0.000e+0
Identity = 592/595 (99.50%), Postives = 595/595 (100.00%), Query Frame = 1

Query:   61 MIMDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNRHPKKNKVIITNGAN 1845
            MIMDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKW+NPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPQLPQLVLLLKQYLLQRDLNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQK+FPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVSTN+TNEANNNNNNSNNNHSSSPSKKFDSDFNRHPKKNKVIITNGAN
Sbjct:    1 MIMDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWENPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPQLPQLVLLLKQYLLQRDLNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKKFPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVSTNSTNEANNNNNNSNNNHSSSPSKKFDSDFNRHPKKNKVIITNGAN 595

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Match: SMESG000017326.1 (SMESG000017326.1)

HSP 1 Score: 1097.42 bits (2837), Expect = 0.000e+0
Identity = 590/593 (99.49%), Postives = 593/593 (100.00%), Query Frame = 1

Query:   67 MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNRHPKKNKVIITNGAN 1845
            MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKW+NPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPQLPQLVLLLKQYLLQRDLNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQK+FPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVSTN+TNEANNNNNNSNNNHSSSPSKKFDSDFNRHPKKNKVIITNGAN
Sbjct:    1 MDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQNELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVLEFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWENPLWTLNDIIKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPQLPQLVLLLKQYLLQRDLNEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRNLIKEKFSQKKFPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRCNINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVSTNSTNEANNNNNNSNNNHSSSPSKKFDSDFNRHPKKNKVIITNGAN 593

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Match: SMESG000043040.1 (SMESG000043040.1)

HSP 1 Score: 67.3958 bits (163), Expect = 1.661e-12
Identity = 43/124 (34.68%), Postives = 64/124 (51.61%), Query Frame = 1

Query: 1081 FLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEG------NTSILGRIIRITPEVMKYRNLIKEKFSQ 1434
            F ELYGR F+YFN+ I       +  K   L    G   SSI+ I+DP++  ND+ +S YG  +I+ AF +AY  L   + P       G      N SILG II ++   + +R  I+ +F++
Sbjct:    3 FFELYGRCFNYFNSAIYVTKSGGYRIK---LDKSVGEK-SSIITIDDPIDKDNDVAKSCYGLFNIRHAFSHAYCLLYSKVAPICMIDNNGDCEIPMNQSILGSIINLSKNSIVFRQRIQSEFAR 122

[Close]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Match: SMESG000016569.1 (SMESG000016569.1)

HSP 1 Score: 67.3958 bits (163), Expect = 1.661e-12
Identity = 43/124 (34.68%), Postives = 64/124 (51.61%), Query Frame = 1

Query: 1081 FLELYGRNFDYFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSYGALHIKMAFDYAYNTLSRVILPQSAQLYEG------NTSILGRIIRITPEVMKYRNLIKEKFSQ 1434
            F ELYGR F+YFN+ I       +  K   L    G   SSI+ I+DP++  ND+ +S YG  +I+ AF +AY  L   + P       G      N SILG II ++   + +R  I+ +F++
Sbjct:    3 FFELYGRCFNYFNSAIYVTKSGGYRIK---LDKSVGEK-SSIITIDDPIDKDNDVAKSCYGLFNIRHAFSHAYCLLYSKVAPICMIDNNGDCEIPMNQSILGSIINLSKNSIVFRQRIQSEFAR 122

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BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Match: SMESG000041562.1 (SMESG000041562.1)

HSP 1 Score: 56.225 bits (134), Expect = 7.164e-8
Identity = 47/191 (24.61%), Postives = 90/191 (47.12%), Query Frame = 1

Query:  499 LDGLHEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTELHLPTSDIDVVIFGKWDNPLWTL--NDI----------IKKSGIASDSKVLDRATVPIVKMTDKETEVRIDISFNMKNGIQSANLIKSFIKEYPXXXXXXXXXXXXXXXXXXNEVWTGGISSYSLILMCVSFMKLRA 1035
            L  L  E+   +  I+P  +  ++ +++  ++ E+V   +P A+  +FGS         SD+DV +    D+ L +L  N++          +KK         + +A VPI+K   K   ++ DIS N   G+Q+  ++K +    P +  L  L+K      ++ +   G +SSY+ +LM + F++ R 
Sbjct:  740 LVKLRAELNAKFKSIVPNNDRPKIAEKIFDKITEIVKALYPIARPQLFGSTINGFMTKASDLDVCLEFYVDDKLQSLSNNEVSNRLKTIGRELKKLNTVQRIDYILKAKVPIIKFYMKNNNIQGDISINNSLGLQNTKMLKVYADLSPCVKLLGNLIKYVAKSCEIGDASQGTLSSYAYMLMLIHFLQKRG 930

The following BLAST results are available for this feature:

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Celegans
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Sea Lamprey
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Yeast
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Nematostella
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TENT4A	6.914e-106	48.76	terminal nucleotidyltransferase 4A [Source:HGNC Sy...	[more]
TENT4B	7.788e-105	52.38	terminal nucleotidyltransferase 4B [Source:HGNC Sy...	[more]
TENT4B	3.471e-104	52.38	terminal nucleotidyltransferase 4B [Source:HGNC Sy...	[more]
TENT4A	1.894e-93	51.35	terminal nucleotidyltransferase 4A [Source:HGNC Sy...	[more]
TENT4B	1.777e-85	56.83	terminal nucleotidyltransferase 4B [Source:HGNC Sy...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
gld-4	1.036e-47	36.39	Poly(A) RNA polymerase gld-4 [Source:UniProtKB/Sw...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trf4-1	1.033e-94	48.88	gene:FBgn0030049 transcript:FBtr0112964	[more]
Trf4-1	1.033e-94	48.88	gene:FBgn0030049 transcript:FBtr0112963	[more]
Trf4-1	5.033e-93	48.88	gene:FBgn0030049 transcript:FBtr0331724	[more]
Trf4-1	5.033e-93	48.88	gene:FBgn0030049 transcript:FBtr0071212	[more]
Trf4-1	5.033e-93	48.88	gene:FBgn0030049 transcript:FBtr0071213	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
tent4b	2.618e-106	52.30	terminal nucleotidyltransferase 4B [Source:ZFIN;Ac...	[more]
tent4a	6.669e-103	51.25	terminal nucleotidyltransferase 4A [Source:ZFIN;Ac...	[more]
tent4a	6.682e-89	53.62	terminal nucleotidyltransferase 4A [Source:ZFIN;Ac...	[more]
tent2	1.078e-7	22.55	terminal nucleotidyltransferase 2 [Source:NCBI gen...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TENT4B	5.702e-110	46.23	terminal nucleotidyltransferase 4B [Source:NCBI ge...	[more]
tyms	1.979e-7	22.26	thymidylate synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
tyms	2.011e-7	22.26	thymidylate synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
tyms	2.249e-7	22.26	thymidylate synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
tyms	2.302e-7	22.26	thymidylate synthetase [Source:Xenbase;Acc:XB-GENE...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tent4a	2.783e-107	49.87	terminal nucleotidyltransferase 4A [Source:MGI Sym...	[more]
Tent4b	4.008e-104	52.24	terminal nucleotidyltransferase 4B [Source:MGI Sym...	[more]
Tent4b	4.008e-104	52.24	terminal nucleotidyltransferase 4B [Source:MGI Sym...	[more]
Tent4a	3.115e-94	52.47	terminal nucleotidyltransferase 4A [Source:MGI Sym...	[more]
Tent4a	3.115e-94	52.47	terminal nucleotidyltransferase 4A [Source:MGI Sym...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5XG87\|PAPD7_HUMAN	1.368e-105	48.76	Terminal nucleotidyltransferase 4A OS=Homo sapiens...	[more]
sp\|Q68ED3\|PAPD5_MOUSE	5.718e-104	52.24	Terminal nucleotidyltransferase 4B OS=Mus musculus...	[more]
sp\|Q8NDF8\|PAPD5_HUMAN	6.263e-104	53.41	Terminal nucleotidyltransferase 4B OS=Homo sapiens...	[more]
sp\|Q6PB75\|PAPD7_MOUSE	2.179e-93	52.47	Terminal nucleotidyltransferase 4A OS=Mus musculus...	[more]
sp\|Q7KVS9\|TRF41_DROME	5.045e-92	48.88	Non-canonical poly(A) RNA polymerase protein Trf4-...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
T1J4Z7	1.970e-118	49.46	Uncharacterized protein OS=Strigamia maritima OX=1...	[more]
V3ZFX5	8.851e-118	45.12	Uncharacterized protein OS=Lottia gigantea OX=2251...	[more]
R7US80	3.653e-117	52.63	Uncharacterized protein OS=Capitella teleta OX=283...	[more]
A0A1S3I2A4	2.421e-113	45.36	non-canonical poly(A) RNA polymerase PAPD5-like OS...	[more]
A0A0C9R9K8	3.796e-112	47.52	Papd5_1 protein OS=Fopius arisanus OX=64838 GN=Pap...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
tent4a	8.689e-102	49.33	terminal nucleotidyltransferase 4A [Source:NCBI ge...	[more]
tent4b	2.995e-99	51.90	terminal nucleotidyltransferase 4B [Source:ZFIN;Ac...	[more]
TENT4A	1.608e-96	49.18	non-canonical poly(A) RNA polymerase PAPD7-like [S...	[more]
TUT4	6.727e-9	28.29	terminal uridylyltransferase 4 [Source:NCBI gene;A...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000007887.1	2.526e-36	43.56	pep scaffold:Pmarinus_7.0:GL478966:13667:20299:-1 ...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
PAP2	1.833e-46	34.88	Non-canonical poly(A) polymerase; involved in nucl...	[more]
TRF5	3.096e-43	33.97	Non-canonical poly(A) polymerase; involved in nucl...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO40179	1.357e-69	46.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
tent4a	3.339e-103	50.69	terminal nucleotidyltransferase 4A [Source:NCBI ge...	[more]
tent4b	4.384e-101	53.76	terminal nucleotidyltransferase 4B [Source:NCBI ge...	[more]
ENSORLT00000036168.1	9.652e-92	47.27	non-canonical poly(A) RNA polymerase PAPD7 [Source...	[more]
tent2	9.485e-12	21.83	terminal nucleotidyltransferase 2 [Source:NCBI gen...	[more]

BLAST of non-canonical poly(A) RNA polymerase PAPD5-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000017326.1	0.000e+0	99.50	SMESG000017326.1	[more]
SMESG000017326.1	0.000e+0	99.49	SMESG000017326.1	[more]
SMESG000043040.1	1.661e-12	34.68	SMESG000043040.1	[more]
SMESG000016569.1	1.661e-12	34.68	SMESG000016569.1	[more]
SMESG000041562.1	7.164e-8	24.61	SMESG000041562.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30002251 ID=SMED30002251|Name=non-canonical poly(A) RNA polymerase PAPD5-like|organism=Schmidtea mediterranea sexual|type=transcript|length=2007bp
TCTTACTTAGTTGTTTAAATAAGCGAATATCTATCTCAATTCAAGTGCAA
TCACCCTGGTATGATAATGGATTCAAATTACTCGTGGAATCAACCAGAGC
ATAATGGACCGGCCCAAAAGATTTGGTCCAAAGCTTATTTAGATGTTTTT
ATAGACAAGATCATTAAACAAAGTTCAACCAATCTTCACAATTATCCGTA
TTTTCAAAATGAATTACCTATACATTCAGCATTTACACCAAACGTCAAAG
ATGCTTGGCATAATCCACCAATACGATTGGAAGAATATTTAGTTTCAGCT
ACAGATGATGAAAATTGCAAAATTAATGATCAAAAAGAGAAATTTTTAAA
CGAAGTTTTAGAATTTATTAAACGAAAACGTGAATATAATAAAGCCAGTA
CATTTGGATATGACATTCAATTGCAATTCGGAATGATATCGACAGTCAAT
TCAGACATGTTTCCATGGAACGTTAAAAATAAGGTTTACCAGAAAAATTT
GGATGGATTACACGAAGAAATTTTAGATTTTTACAATTATATAATGCCAA
CTGTGGAAGAACAAGAAATGCGCCAAGAAGTAGTTGCGAGACTAAAAGAA
GTAGTTTTAAAAGAGTGGCCAGAAGCCAAAGTTGATGTTTTTGGAAGTTT
CAAGACAGAGCTACATCTCCCTACCAGCGACATTGATGTTGTGATATTTG
GTAAATGGGATAATCCTCTCTGGACTCTAAATGACATAATAAAAAAAAGT
GGGATTGCATCTGATAGTAAAGTTCTCGATAGAGCTACAGTTCCAATCGT
TAAAATGACAGACAAGGAAACCGAAGTTAGAATCGATATTAGCTTCAATA
TGAAAAATGGCATACAATCAGCAAATTTAATAAAATCATTCATTAAAGAA
TATCCTCAACTTCCGCAATTAGTTTTGCTTCTCAAGCAATATCTTCTACA
AAGAGATTTAAATGAAGTATGGACTGGCGGAATTAGTTCATATTCTTTAA
TTTTGATGTGTGTCAGTTTCATGAAGTTACGGGCTAAAAAAATAAATTCC
CAAGAAAATTTAGGTGAAACTCTAATTATGTTTCTGGAGTTATATGGTCG
TAATTTCGATTATTTTAATACGGGAATTCGTACAGAGGGTGACAGTTGTC
ATGTTCCAAAAGAAGAGATTTTAAAAAACATGGAAGGAAATCATTGGTCA
TCTATCCTTTGTATAGAAGATCCCTTAAACCCGGTTAACGATATCGGTCG
AAGTTCATATGGTGCATTGCATATTAAAATGGCATTCGATTATGCCTATA
ACACACTTTCACGAGTAATTTTACCCCAGTCAGCTCAATTATACGAAGGA
AACACTTCAATTCTTGGTAGAATCATCCGAATAACACCCGAGGTGATGAA
ATACCGCAATTTAATAAAAGAAAAATTTTCTCAAAAGAGATTTCCCGAAC
AAATCCAAATTAACATTGAAAATACAATAAAAACTTCGGAAAAAATTTCT
CAGAATGATGTTAAAAAGGATTCTAATACGAATAATAGTAACCAAAAAAT
GATCAGATGTAACATCAATGAACAGGGCGATGTTCCAACGAAACTCGAAA
TGTCATATTCACATAGCCTTCAGAGAAAACCTAAATTTAATCAGAAGAAA
AACGTTGAGGCCATTTTTAAATCAAACAATTCGAAAATAGCCAGCTCAAA
AGTTTCAACCAATACCACTAATGAAGCCAATAATAACAACAATAACAGCA
ATAATAATCACTCAAGCAGTCCTTCGAAAAAATTCGATTCAGATTTCAAC
AGACATCCGAAAAAAAACAAAGTTATTATCACTAATGGAGCCAATTGAAT
TCAATATTAATATTATTAATTTGGTTTTTTGTCAAATTTGTAGATATTCC
CAATTTAGTTACTTTATAGTGTTTTACGTTTTGAAAATTGCGCATTATTT
ATCAGAAATAGCGGATTTATTCAACTGAATTGTCAGAAATTATTTTCTGG
TTAATTC

protein sequence of SMED30002251-orf-1

>SMED30002251-orf-1 ID=SMED30002251-orf-1|Name=SMED30002251-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=596bp
MIMDSNYSWNQPEHNGPAQKIWSKAYLDVFIDKIIKQSSTNLHNYPYFQN
ELPIHSAFTPNVKDAWHNPPIRLEEYLVSATDDENCKINDQKEKFLNEVL
EFIKRKREYNKASTFGYDIQLQFGMISTVNSDMFPWNVKNKVYQKNLDGL
HEEILDFYNYIMPTVEEQEMRQEVVARLKEVVLKEWPEAKVDVFGSFKTE
LHLPTSDIDVVIFGKWDNPLWTLNDIIKKSGIASDSKVLDRATVPIVKMT
DKETEVRIDISFNMKNGIQSANLIKSFIKEYPQLPQLVLLLKQYLLQRDL
NEVWTGGISSYSLILMCVSFMKLRAKKINSQENLGETLIMFLELYGRNFD
YFNTGIRTEGDSCHVPKEEILKNMEGNHWSSILCIEDPLNPVNDIGRSSY
GALHIKMAFDYAYNTLSRVILPQSAQLYEGNTSILGRIIRITPEVMKYRN
LIKEKFSQKRFPEQIQINIENTIKTSEKISQNDVKKDSNTNNSNQKMIRC
NINEQGDVPTKLEMSYSHSLQRKPKFNQKKNVEAIFKSNNSKIASSKVST
NTTNEANNNNNNSNNNHSSSPSKKFDSDFNRHPKKNKVIITNGAN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0043631	RNA polyadenylation
GO:0006364	rRNA processing
GO:0006397	mRNA processing
GO:0007049	cell cycle
GO:0007067	mitotic nuclear division
GO:0051301	cell division
GO:0071044	histone mRNA catabolic process
GO:0071897	DNA biosynthetic process

Vocabulary: **INTERPRO**
Term	Definition
IPR040137	TENT4A
IPR002058	PAP_assoc
IPR002934	Polymerase_NTP_transf_dom

Vocabulary: **molecular function**
Term	Definition
GO:0016779	nucleotidyltransferase activity
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0004652	polynucleotide adenylyltransferase activity
GO:0016740	transferase activity
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002058	PAP/25A-associated	PFAM	PF03828	PAP_assoc	coord: 333..392 e-value: 7.3E-13 score: 48.5
IPR002934	Polymerase, nucleotidyl transferase domain	PFAM	PF01909	NTP_transf_2	coord: 176..280 e-value: 4.5E-13 score: 49.3
None	No IPR available	GENE3D	G3DSA:3.30.460.10		coord: 165..269 e-value: 2.4E-101 score: 340.9
None	No IPR available	GENE3D	G3DSA:1.10.1410.10		coord: 136..417 e-value: 2.4E-101 score: 340.9
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 478..497
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 543..595
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 543..573
None	No IPR available	PANTHER	PTHR23092	POLY(A) RNA POLYMERASE	coord: 104..496
None	No IPR available	CDD	cd05402	NT_PAP_TUTase	coord: 170..278 e-value: 1.69606E-32 score: 118.814
None	No IPR available	SUPERFAMILY	SSF81301	Nucleotidyltransferase	coord: 133..293
None	No IPR available	SUPERFAMILY	SSF81631	PAP/OAS1 substrate-binding domain	coord: 282..420
IPR040137	Terminal nucleotidyltransferase 4A	PANTHER	PTHR23092:SF24	NON-CANONICAL POLY(A) RNA POLYMERASE PAPD7	coord: 104..496