Ig-like domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002228 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: CG1504 (gene:FBgn0031100 transcript:FBtr0335041) HSP 1 Score: 53.1434 bits (126), Expect = 5.278e-7 Identity = 36/130 (27.69%), Postives = 63/130 (48.46%), Query Frame = 1 Query: 310 RSCPDQCASCLHDDMLCEKVGLLEIP--KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLS 690 +SCP +C +LC GL +IP +L ++N+ + F P++ +F+ R L LS+ +N+ RI+Q+A L L+ + ++ AF L NL + L + +++ AF G S Sbjct: 28 KSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKNNF--PIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAGTS 155
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: CG1504 (gene:FBgn0031100 transcript:FBtr0306678) HSP 1 Score: 53.1434 bits (126), Expect = 5.278e-7 Identity = 36/130 (27.69%), Postives = 63/130 (48.46%), Query Frame = 1 Query: 310 RSCPDQCASCLHDDMLCEKVGLLEIP--KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLS 690 +SCP +C +LC GL +IP +L ++N+ + F P++ +F+ R L LS+ +N+ RI+Q+A L L+ + ++ AF L NL + L + +++ AF G S Sbjct: 28 KSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKNNF--PIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAGTS 155
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: CG1504 (gene:FBgn0031100 transcript:FBtr0335042) HSP 1 Score: 53.1434 bits (126), Expect = 5.278e-7 Identity = 36/130 (27.69%), Postives = 63/130 (48.46%), Query Frame = 1 Query: 310 RSCPDQCASCLHDDMLCEKVGLLEIP--KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLS 690 +SCP +C +LC GL +IP +L ++N+ + F P++ +F+ R L LS+ +N+ RI+Q+A L L+ + ++ AF L NL + L + +++ AF G S Sbjct: 28 KSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKNNF--PIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAGTS 155
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Match: CG1504 (gene:FBgn0031100 transcript:FBtr0335040) HSP 1 Score: 53.1434 bits (126), Expect = 5.278e-7 Identity = 36/130 (27.69%), Postives = 63/130 (48.46%), Query Frame = 1 Query: 310 RSCPDQCASCLHDDMLCEKVGLLEIP--KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLS 690 +SCP +C +LC GL +IP +L ++N+ + F P++ +F+ R L LS+ +N+ RI+Q+A L L+ + ++ AF L NL + L + +++ AF G S Sbjct: 28 KSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKNNF--PIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAGTS 155
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: slit3 (slit homolog 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-010306-4]) HSP 1 Score: 58.9214 bits (141), Expect = 2.139e-8 Identity = 62/203 (30.54%), Postives = 92/203 (45.32%), Query Frame = 1 Query: 307 VRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLS-IQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEIL 909 V CP C +C ++ + C + GL EIP L E I V I +Q M + +G FS Y+KL + + + ++ I + A S L L ++ N I F L + L L N I N L V+T +QN +LLSL +Q I+ + L +K+L L NPF+C+C L WL++ L Sbjct: 269 VTICPAAC-TCNNNIVDCRRKGLTEIPANLPEGI--VEIRLEQNMIKNIPAGAFSTYKKLKRIDLSKNQISEIAEDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKI-------NCLRVNTFKDLQNLNLLSLYDNKLQTISKGLFAP-----------------LRAIKTLHLAQNPFMCDCHLKWLADYL 444
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4cb (leucine rich repeat containing 4C, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-080327-5]) HSP 1 Score: 56.225 bits (134), Expect = 8.797e-8 Identity = 67/294 (22.79%), Postives = 114/294 (38.78%), Query Frame = 1 Query: 448 LTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGL-SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEVPISTS----------PIKYKCKAQNELGNSEIDLIL 1287 ++SG F L L++ + NL + + L L ++ S N +I+ S+F L +L L + + ++ +F+ L S+ L++ +++L LP +L P+ H L+ + L NP+ CNC +LWLS L + +C SPP L+ +Y+ L + C P I++ +D+ L C N +T + W S + + K I V + Y C N LGN+ IL Sbjct: 189 ISSGAFQGLSNLRYLNLGMCNLKEVPN--IQPLIRLDELEMSGNQLTVIQPSSFKGLVHLQKLWMMHAQVQTIERNSFDDLHSLRELNLAHNNLTFLPHDLYTPLHH-------------------------LQRVHLHHNPWNCNCDILWLSWWLRETVP--------TNTSCCARCNSPPSLKGRYIGELDQSYFQCYAPVIIEPPVDLNLTEGMAAELKC------RTNSVTSVSWLTPNGSIITHGTLKMRINVQNDGTLNFTNVTLQDTGTYTCYVSNMLGNTSASAIL 441
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4cb (leucine rich repeat containing 4C, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-080327-5]) HSP 1 Score: 56.225 bits (134), Expect = 8.797e-8 Identity = 67/294 (22.79%), Postives = 114/294 (38.78%), Query Frame = 1 Query: 448 LTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGL-SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEVPISTS----------PIKYKCKAQNELGNSEIDLIL 1287 ++SG F L L++ + NL + + L L ++ S N +I+ S+F L +L L + + ++ +F+ L S+ L++ +++L LP +L P+ H L+ + L NP+ CNC +LWLS L + +C SPP L+ +Y+ L + C P I++ +D+ L C N +T + W S + + K I V + Y C N LGN+ IL Sbjct: 189 ISSGAFQGLSNLRYLNLGMCNLKEVPN--IQPLIRLDELEMSGNQLTVIQPSSFKGLVHLQKLWMMHAQVQTIERNSFDDLHSLRELNLAHNNLTFLPHDLYTPLHH-------------------------LQRVHLHHNPWNCNCDILWLSWWLRETVP--------TNTSCCARCNSPPSLKGRYIGELDQSYFQCYAPVIIEPPVDLNLTEGMAAELKC------RTNSVTSVSWLTPNGSIITHGTLKMRINVQNDGTLNFTNVTLQDTGTYTCYVSNMLGNTSASAIL 441
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25]) HSP 1 Score: 53.5286 bits (127), Expect = 6.078e-7 Identity = 76/346 (21.97%), Postives = 125/346 (36.13%), Query Frame = 1 Query: 460 NFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEP-ENVNELTKIGWFPSKNS-----SLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGE---------KPAIVLENSTFK-FEETFIK------QSFLWEKVFSLFEMICAIFGT 1425 N + +L +L + + L IR + L LR + + +IE +AF D+K +++ L++ ++ L SLP +L P L L+ + L NP++CNC +LWLS L + + +C +PP L+ +Y+ L + C P IV+ D+ L C +VN +T G + S S+L F V + + +Y C N GN+ +L + + E+S + F ETFI LW +V +IF T Sbjct: 214 NLTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAF-------------DDLK---------NLEELNLSHNSLHSLPHDLFTP-------------------------LQKLERVHLNHNPWVCNCDVLWLSWWLKETVPSNTTCCA--------RCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWITPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTG-QYTCMVTNSAGNTTATAVLNVTAADVSVNYTYFTTVTVETEDSALRTFNETFIHIPGPTPSGHLWHEVVPTTASSLSIFAT 503
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Match: lrrc4ba (leucine rich repeat containing 4Ba [Source:ZFIN;Acc:ZDB-GENE-080327-25]) HSP 1 Score: 53.5286 bits (127), Expect = 6.078e-7 Identity = 76/346 (21.97%), Postives = 125/346 (36.13%), Query Frame = 1 Query: 460 NFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEP-ENVNELTKIGWFPSKNS-----SLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGE---------KPAIVLENSTFK-FEETFIK------QSFLWEKVFSLFEMICAIFGT 1425 N + +L +L + + L IR + L LR + + +IE +AF D+K +++ L++ ++ L SLP +L P L L+ + L NP++CNC +LWLS L + + +C +PP L+ +Y+ L + C P IV+ D+ L C +VN +T G + S S+L F V + + +Y C N GN+ +L + + E+S + F ETFI LW +V +IF T Sbjct: 214 NLTPLVRLEELELSGNRLEIIRPGSFQGLESLRKLWLMHSQMSVIERNAF-------------DDLK---------NLEELNLSHNSLHSLPHDLFTP-------------------------LQKLERVHLNHNPWVCNCDVLWLSWWLKETVPSNTTCCA--------RCHAPPYLKGKYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWITPNGTLMTHGSYRVRISVLHDGTLNFTNVTLRDTG-QYTCMVTNSAGNTTATAVLNVTAADVSVNYTYFTTVTVETEDSALRTFNETFIHIPGPTPSGHLWHEVVPTTASSLSIFAT 503
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: lrrc4b (leucine rich repeat containing 4B [Source:NCBI gene;Acc:100124949]) HSP 1 Score: 58.9214 bits (141), Expect = 2.051e-8 Identity = 69/293 (23.55%), Postives = 109/293 (37.20%), Query Frame = 1 Query: 460 NFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEP-ENVNELTKIGWFPSKNS-----SLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGEKPA 1314 N + +L +L + + L IR + L+ LR + IIE +AF D+K S++ L++ +++L+SLP +L P+ L+ + L NP+ CNC +LWLS L + N +C SPP L+ +Y+ L + C P IV+ D+ L C +VN LT G + S S+L F V + + +Y C N GN+ L + PA Sbjct: 209 NLTALVRLEELELSGNRLEMIRPGSFQGLTSLRKLWLMHAHVTIIERNAF-------------DDLK---------SLEELNLSHNNLMSLPHDLFTPLHR-------------------------LERVHLNHNPWHCNCDVLWLSWWLKETVP--------NNTTCCARCHSPPNLKMRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTG-QYTCMVTNSAGNTTATATLNVSAAADPA 445
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: slit1 (slit guidance ligand 1 [Source:NCBI gene;Acc:100036682]) HSP 1 Score: 53.1434 bits (126), Expect = 1.565e-6 Identity = 71/249 (28.51%), Postives = 103/249 (41.37%), Query Frame = 1 Query: 301 IAVRSCPDQCASCLHDDMLCEKVGLLEIPK-LNENIKNVTI-LNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTL-SIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNC 1038 +++ SCP C +C + + C GL IP L E + + + LN P G FS Y+KL I LSN N+I + A A LR+++ E I SA + L I L+ N + DT +QN LLSL IQ +A L +++L L NPFIC+C L WL++ L T I++ +C SP L + + + K C Sbjct: 276 LSIGSCPAMC-TCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSVP---PGAFSPYKKLR--RIDLSN-NQISEIAPDAFQGLRSLNSLEGAAQI---SAMYGL------------ILLNANKINCIRADTFQDLQNLSLLSLYDNKIQSLAKGTFA-----------------ALRAIQTLHLAQNPFICDCNLKWLADFLR-----TNPIETSGA-----RCASPRRLANKRIGQIKSKKFRC 475
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 50.8322 bits (120), Expect = 8.405e-6 Identity = 69/248 (27.82%), Postives = 108/248 (43.55%), Query Frame = 1 Query: 304 AVRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDN-QAFNGLSVDTL-SIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNC 1038 +V CP C +C ++ + C GL EIP L E I + + +Q V+ G FS Y+KL I LSN N+I + A A LR+++ L++ + L + + + + L N N L VD+ + N +LLSL +Q IA L +++L L NPFIC+C L WL++ L+ T I++ +C SP L + + + K C Sbjct: 278 SVLHCPAAC-TCSNNIVDCRGKGLTEIPTNLPETITEMRL--EQNSIKVIPPGAFSPYKKLR--RIDLSN-NQISEIAADAFQGLRSLN-----SLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHNLNLLSLYDNKLQTIAKGTFAP-----------------LRAIQTLHLAQNPFICDCHLKWLADYLH-----TNPIETSGA-----RCTSPRRLANKRIGQIKSKKFRC 487
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 50.8322 bits (120), Expect = 8.542e-6 Identity = 69/248 (27.82%), Postives = 108/248 (43.55%), Query Frame = 1 Query: 304 AVRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDN-QAFNGLSVDTL-SIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNC 1038 +V CP C +C ++ + C GL EIP L E I + + +Q V+ G FS Y+KL I LSN N+I + A A LR+++ L++ + L + + + + L N N L VD+ + N +LLSL +Q IA L +++L L NPFIC+C L WL++ L+ T I++ +C SP L + + + K C Sbjct: 278 SVLHCPAAC-TCSNNIVDCRGKGLTEIPTNLPETITEMRL--EQNSIKVIPPGAFSPYKKLR--RIDLSN-NQISEIAADAFQGLRSLN-----SLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHNLNLLSLYDNKLQTIAKGTFAP-----------------LRAIQTLHLAQNPFICDCHLKWLADYLH-----TNPIETSGA-----RCTSPRRLANKRIGQIKSKKFRC 487
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Match: atad3a (ATPase family, AAA domain containing 3A [Source:Xenbase;Acc:XB-GENE-946129]) HSP 1 Score: 50.8322 bits (120), Expect = 8.687e-6 Identity = 69/248 (27.82%), Postives = 108/248 (43.55%), Query Frame = 1 Query: 304 AVRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDN-QAFNGLSVDTL-SIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNC 1038 +V CP C +C ++ + C GL EIP L E I + + +Q V+ G FS Y+KL I LSN N+I + A A LR+++ L++ + L + + + + L N N L VD+ + N +LLSL +Q IA L +++L L NPFIC+C L WL++ L+ T I++ +C SP L + + + K C Sbjct: 278 SVLHCPAAC-TCSNNIVDCRGKGLTEIPTNLPETITEMRL--EQNSIKVIPPGAFSPYKKLR--RIDLSN-NQISEIAADAFQGLRSLN-----SLVLYGNKITELPKGLFEGLVLLQLLLLNANKINCLRVDSFQDLHNLNLLSLYDNKLQTIAKGTFAP-----------------LRAIQTLHLAQNPFICDCHLKWLADYLH-----TNPIETSGA-----RCTSPRRLANKRIGQIKSKKFRC 487
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:MGI Symbol;Acc:MGI:2444277]) HSP 1 Score: 60.4622 bits (145), Expect = 5.709e-9 Identity = 74/278 (26.62%), Postives = 116/278 (41.73%), Query Frame = 1 Query: 253 MTLFHFKISVIIPLLIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 +T+ F + L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 43 VTMGPFGALCLAWALLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 279
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:MGI Symbol;Acc:MGI:2444277]) HSP 1 Score: 60.077 bits (144), Expect = 7.204e-9 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 13 LLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 235
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:MGI Symbol;Acc:MGI:2444277]) HSP 1 Score: 60.077 bits (144), Expect = 7.204e-9 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 13 LLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 235
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:MGI Symbol;Acc:MGI:2444277]) HSP 1 Score: 60.077 bits (144), Expect = 7.204e-9 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 13 LLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 235
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Match: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2 [Source:MGI Symbol;Acc:MGI:2444277]) HSP 1 Score: 60.077 bits (144), Expect = 7.204e-9 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 13 LLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 235
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5RKR3|ISLR2_MOUSE (Immunoglobulin superfamily containing leucine-rich repeat protein 2 OS=Mus musculus OX=10090 GN=Islr2 PE=1 SV=1) HSP 1 Score: 60.077 bits (144), Expect = 5.039e-8 Identity = 72/264 (27.27%), Postives = 111/264 (42.05%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASCL----HDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL-NLVILKLDNMGDIKLDNQAFNGLSV----DTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSE-ILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI 1053 L+ VR+CP+ CA C+ H C L E+P+ L N+ +++ + VL G F ++T L + S + + AL+ LS+L+N+D S N +I + + L NL L+L M +L + + L +L I N+ L +L L L L+L NPF C+C L+WL + R+S DS C SPPEL+ V+ L C PP++ Sbjct: 13 LLGVVRACPEPCA-CVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT--VLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFD-------------------------ALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVS-LPEPDSI-------ACASPPELQGVPVHRL--PALPCAPPSV 235
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A5P8I4L0 (PXDN-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 126.331 bits (316), Expect = 4.490e-27 Identity = 135/477 (28.30%), Postives = 216/477 (45.28%), Query Frame = 1 Query: 271 KISVIIPLLIIAV---------RSCPDQCA--SCLHDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYR----KLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNR-----ISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSW---KRFIEVPISTSPIKYKCKAQNELGNSEIDLILAW-----NEGEK-------------PAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIY 1575 KI ++P+L+ + CP C +C + C GLL+IP L++ + + NQ+F +P LT NFS Y K+ ++++ L I S L++LR +D S N I F L+L L+LD+ I+ +F GL+V LS+ + +L L E+ I+ ++KL+L +N L +D + + + L L++ +NPF C C L WL+ +L +R +S +K I + Q C P ++ + + L K +C P + IDV S + L C I EP+ + + W ++ +P+ K + V + KYKC +N + + + W N + P + NST F +EK F+L EMI + GT IT+ILFL C Y HL + K+ K K Y SYE + SD++ Y Sbjct: 2 KIPFLLPMLLFILFLAKTSAHFNPCPSVCHEMACQTGVLACTDGGLLQIPPVLHQKTHKIIVSNQRFSSPHLTYSNFSNYGPPNYKIEKIALQFCELVSIASNCFSHLTDLRVLDLSHNLLGEIPPDTFKALHLQFLRLDDNKMIQFHRFSFRGLNVAELSLFDCNLTELDFEVFSEISERLKKLILTNNKLNVIDKRFRILFENLPDLQINENPFNCTCNLRWLNSVLVSRKKAINLSSSKRIPNQAQ------CNYPDRVKGKQIADLDLKDFDCDSPRLKLIDVFMTSTSSAKLTC-ISEPK-AHSSPDVIWMTEHKNTYVPEIQSIEKASLSVLRKSRIDKYKCVIKNNNDYVTVVISIHWPVKRVNNASQSLNTLGVSPNDMIPYLPNANSTLHVRSVF------YEKQFTLLEMIGGVVGTFTITMILFL---CIY---RHLAMTMKRNDK--KKWYLSYETAIGSDSQTY 456
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A0R3SAT8 (Ig-like domain-containing protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1502 PE=4 SV=1) HSP 1 Score: 127.872 bits (320), Expect = 5.487e-27 Identity = 130/463 (28.08%), Postives = 214/463 (46.22%), Query Frame = 1 Query: 280 VIIPLLIIAVRSC-PDQ----CASCLHDDMLCEKVGLLEI--PKLNENIKNVTILNQQFMNPVLTSGNFSVYR----KLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPI--AHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNR-----------ISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVG-------LNCMIKEPENVNELTKIGWFPSK--NSSLLPKSWKR-----FIEVPISTSPIK-------------YKCKAQNELGNSEIDLILAW-----NEGEKP---------------AIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLL 1455 +I+PLL + R D+ C C++ + C++ G L + L I+ V I++Q+F + L+ N S Y ++ +L+I L I S L+ L +D S+N+ I+ + F L L +L+LD+ + LD +AF L+V +LS+QN L SL E+ +P+ + ++ L L SN L +LD++ +P L L L NPF+C+CKL+WLS IL + I+ +L+ DD +P C SP LR + + +L C PP + ++V + S + G +IK + ++ WF + L+P S R +EV +S S + + C + GN+ DL L W N KP LE +F+ + + F + K F++ E+I A+ GT T++LFL+ Sbjct: 14 LILPLLTVRGREVRADEVCQICDGCIYGSISCQEAGRLHMLPNDLPSGIRKVIIVSQRFDSQFLSRPNISSYSLPGSEIQELTIMDCGLRAIESRTFSGLNSLTKLDLSKNSLSRIQGNTFSGLRLDLLRLDDNQGLTLDAEAFENLTVSSLSMQNCGLRSLSFEVFRPLLQSGTLTTLRLTSNSLTTLDARFEPFFRNLSFLSLAKNPFVCDCKLMWLSRILQRKRRADNDDAFPMINDDRLL--IEPDDDHPICESPGRLRGKQIVSLASSDFYCGPPQMRALEVDFTSLRVGGSEAVNTTAGILIKCAAQGSPEMQLTWFRRDRWGAGLIPLSGLRQISPGVVEVSVSRSLLAKNSTSDSEDSGELFTCMGIDTYGNTSADLFLKWPTLPTNSAVKPQSPDKRSSLESSSSDTFYLEGEQQRFQTDRLDE-FFFMKKFTILELIGAVVGTFTATIMLFLM 473
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A0R3TNY6 (Ig-like domain-containing protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9134 PE=4 SV=1) HSP 1 Score: 117.472 bits (293), Expect = 1.135e-23 Identity = 126/464 (27.16%), Postives = 207/464 (44.61%), Query Frame = 1 Query: 280 VIIPLLIIAVRSCPDQ-----CASCLHDDMLCEKVGLLEI--PKLNENIKNVTILNQQFMNPVLTSGNFSVYR----KLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPI--AHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSY----------NQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVG-------LNCMIKEPENVNELTKIGWFPSK--NSSLLPKSWKRF-----IEVPISTSPIK-------------YKCKAQNELGNSEIDLILAWNEGEKPAIV----------------------LENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLL 1455 +++PLL + R C C++ + C++ G L + L I+ V I++Q+F + L+ N S Y + +L+I L I S L+ L +D S+N+ I+ + F L L +L+LD+ + LD +AF L+V +LS+QN L SL E+ +P+ + ++ L L SN L +LD + +P L L L NPF C+CKL+WLS L R D++ DD +P C SP LR + + TL C PP + ++V + S+ + G +IK + ++ WF + L+P S + +EV IS S + + C + GN+ DL L W + +IV ++ +FK + F + K F++ E+I A+ GT T++LFL+ Sbjct: 14 LVLPLLAVRGREIKADEVCQICDGCIYGSISCQEAGRLHMLPNDLPPGIRKVIIVSQRFDSQFLSRQNISSYSLPGTVIQELTIMDCGLRAIESRTFSGLNSLTKLDVSKNSLSRIQGNTFSGLRLDLLRLDDNQGLTLDAEAFENLTVSSLSMQNCGLRSLSFEVFRPLLQSGTLTTLRLTSNSLTTLDIRFEPFFRNLSFLSLAKNPFTCDCKLMWLSRTL-QRKRREDNDDAFPMINDDILLIEPDDDHPICESPSRLRGKQIVTLASTDFYCGPPQMKALEVDFSSFRVGGGETVNTTAGIVIKCAAQGSPEMQLAWFQRDRWGNGLVPLSGSKHVSPGVVEVSISRSLLAKNSTGGSEELGELFTCMGIDTYGNTSADLSLRWPAFQPTSIVPSQPSDKRNSPVPPAGDADYLEVDQKSFKTDRL---DEFFFMKKFTVLELIGAVVGTFTATIMLFLM 473
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: I1ZIL5 (Slit-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 115.546 bits (288), Expect = 1.869e-23 Identity = 136/464 (29.31%), Postives = 211/464 (45.47%), Query Frame = 1 Query: 316 CPDQC--ASCLHDDMLCEKVGLLEIPKLN--ENIKNVTILNQQFMNPVLTSGNFSVYRK----LTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLY----PKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGW------------FPSKNSSLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAW-----NEGEKPAIVLENST--FKFEETFIKQS------------FLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKS-YPSYERGVYSDTRIY 1575 CP+ C +C +LCE GLL+IP +N I+ V + NQ F+ P LT N S Y L L+I +L I A S L L+ +D S N L I + F L+L L LD+ +++L +F GL V +LS+++ HL L E I+ I+ + L L N L L + + GL +L L++N F C+C+L WL+ L R TK D+ + L P C P L+ + L C P + +ID+ S ++C+ + N +++ W +P +NS + S I V + Y C NE GN+ +D+ + W E P N+ F K S +LW K ++ EM+ AI GT +IT++ F+L YV +I +++ ++K+ YE GVYS+++ Y Sbjct: 35 CPELCNQGACKLTMLLCETPGLLQIP-MNPPRGIQKVILSNQNFLYPRLTYTNLSRYGSEEIILKKLTISNCSLTSIESEAFSHLIYLQELDLSSNRLLFIYPNTFKSLSLKTLVLDSNRNLQLAKDSFRGLVVQSLSMKDCHLKILTHESIKQISGYLTTLNLADNRLEYLSNDFDLLFRGLDNLNLENNLFNCSCQLKWLALTLQTR---TKRRDNSPKHSLLRLTNPVCEYPKNLKGSSIENLSIVSFQCQIPKLQRIDIKVTSEITAEISCISDDMSN----SQVKWRYRYNLSPLFYRYPDQNSGVNQAS----IIVSKKSEFDFYSCLIINENGNATVDIKIKWPTLNKEYVESPINSPPNTVNQFNLRNNITKSSVILKEFDKLHVNYLWIKQYTFIEMVLAICGTFIITLVTFILL---YV------VINYRRKNSRSKNILKGYEVGVYSESQTY 477
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A068YC11 (Variable lymphocyte receptor OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000739800 PE=4 SV=1) HSP 1 Score: 115.931 bits (289), Expect = 4.308e-23 Identity = 116/443 (26.19%), Postives = 187/443 (42.21%), Query Frame = 1 Query: 328 CASCLHDDMLCEKVGLLEI--PKLNENIKNVTILNQQFMNPVLTSGNFSVYR----KLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXX--PVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQ----------DDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYL--------SYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLP-------KSWKRFIEVPISTSPIKYKCKAQNE-------------LGNSEIDLILAW---------------------NEGEKPAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLL 1455 C C + + C++ LL + L I+ V I++Q+F + L+ N S Y + +L+I L I S LS L +D S+N+ I+ F L L +L+LD+ + LD++AF L+V +LS+QN L SL E+ QP+ S L+ + P L L L NPF+C+CKL+WLS L R D++ + DD +P C SP LR +++ +L + C PP + ++V + ++ M G+ +IK + ++ WF P + +EV IS S K++ E GN+ DL L W + L N F+ + + F +K F++ E+I A+ GT T++LFL+ Sbjct: 35 CEGCTYGSISCQEADLLHMLPNNLPNGIEKVIIVSQRFDSQFLSRQNISSYTLPGVNIHELTIMHCGLRAIEAGTFSGLSSLTKLDLSKNSLSRIQGHTFSGLRLDLLRLDDNQGLTLDSEAFENLTVSSLSMQNCGLRSLSYEVFQPLVQSRSLTTLRLTSNSLTTLDARFEPFFRNLSFLSLARNPFVCDCKLVWLSRTL-QRKRRADSDDAFRRLNDDRLLIVPDDDHPVCESPNHLRGKHIVSLSTRDFFCGPPQMRALEVDFSDLRVGQSETFNMTGV-VLIKCAAQGSPEMQLAWFRRDRRGGEPIRLPGLRQVASGVVEVSISHSLFAKNSKSETEDAGQLFTCLGVDTYGNTSADLSLRWPALPLLSPLPSSPTSNNRNPMEPSSGDSKYLNNDKGYFQSDRLDEYFFMKK-FTILELIGAVVGTFTATILLFLM 474
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: islr2 (immunoglobulin superfamily containing leucine rich repeat 2 [Source:NCBI gene;Acc:103022455]) HSP 1 Score: 60.077 bits (144), Expect = 6.092e-9 Identity = 90/381 (23.62%), Postives = 160/381 (41.99%), Query Frame = 1 Query: 295 LIIAVRSCPDQCASC---LHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLN-LVILKLDNMGDIKLDNQAFNGL-SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKL-IDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTI-------VQIDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFI---EVPISTSPI-----------------------KYKCKAQNELGNSEIDLILAWNEGEKPAI 1317 +I +V+SCP+QC H + C LL +P L N+ +++ + VL S NF ++T L + + + I + L+ +S+L+N+D S N + L+ L +LK+++ + L AF L + ++ I N+ ++ P LI + L++ NPF C+C+L W+ + I+G+ L I +Q+++ C +P +L+ V T + KL +C PT+ ++ +Y Y MV LNC K N + W + LL + + EVPI+ +P Y C A N++G ++ + L +K A+ Sbjct: 15 VIASVQSCPEQCTCSDKNPHHFVDCAYKDLLLVPLGLPSNVTTLSLSANKIQ--VLKSKNFVSVTQVTSLWLSHNEIVTIERNTLAPMSQLKNLDLSHNKIVNFPWEDLANLSTLQLLKMNHNEMVSLPKDAFTNLKELRSVRINNNKFTTIMEGTFNP-------------------------LIAMVHLQIFSNPFSCSCQLEWMRDW----ITGSHLKISIPDQNNIL--CDAPSDLKGIEV-TKIPKL-DCQAPTVTITYQPNIESTEIYEGY-MVILNCESKG----NPQPTVEWEILAGNQLLTFTLPSIVEKSEVPINGAPTNTRFLIFQNGTLIIPRMSKKEDGNYSCSATNDMGKAQSTVKLTMAGTKKHAV 355
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4cb (leucine-rich repeat-containing protein 4C-like [Source:NCBI gene;Acc:103034014]) HSP 1 Score: 58.5362 bits (140), Expect = 1.400e-8 Identity = 92/378 (24.34%), Postives = 140/378 (37.04%), Query Frame = 1 Query: 376 LEIPKLNEN-IKNVTI--------LN--QQFMNPVLT--SGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFR-------LNLVILKLDNMGDI----KLD------NQ-------AFNGL-------------------------SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEV---------PISTSPIK-YKCKAQNELGNSEIDLIL 1287 LEI +L++N I+N+ I LN + F N + T +G F KL +L +R + + I YA + L LR +D E L F LNL + L + +I +LD NQ +F GL S+ L++ +++L +P +L P+ H L+ + L NP+ CNC +LWLS L + +C SPP L+ +Y+ L + C P IV+ D+ T V L C N LT + W S L + K + V ++ + Y CK N LGN ++L Sbjct: 103 LEILQLSKNHIRNIEIGAFNGLTNLNTLELFDNRLTTIPNGAFEYLSKLKELWLRNNPIESIPSYAFNRLPSLRRLDLGELKRLSYVSDGAFEGLGNLRYLNLGMCNLKEVPNIQPLVRLDELEMSGNQLTVIRPGSFKGLVHLHKLWMMHAQVQIIERNSFDDLQSLGELNLAHNNLTFVPHDLFTPLRH-------------------------LQRVHLHHNPWNCNCDILWLSWWLRETVP--------TNTSCCARCYSPPSLKGRYIGELDQSYFQCYAPVIVESPADLNVTEGTAVELKC------RTNSLTSVSWLTPNGSVLTHGASKGRVTVQNDGTLNFTSVTMQDMGTYTCKVSNMLGNVSASVLL 441
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: slit3 (slit guidance ligand 3 [Source:NCBI gene;Acc:103037708]) HSP 1 Score: 55.0694 bits (131), Expect = 2.511e-7 Identity = 60/200 (30.00%), Postives = 90/200 (45.00%), Query Frame = 1 Query: 316 CPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLS-IQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEIL 909 CP C SC ++ + C + GL EIP L E I V I +Q + + G FS Y+KL + + ++++ I A S L L ++ N I F L + L L N I N L V+T +Q+ +LLSL +Q I+ + L +K+L L NPF+C+C L WL++ L Sbjct: 280 CPASC-SCTNNIVDCRRKGLTEIPANLPEGI--VEIRLEQNLIKSIPPGAFSPYKKLKRIDLSKNHISDIADDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKI-------NCLRVNTFKDLQSLNLLSLYDNKLQTISKGLFTP-----------------LRAIKTLHLAQNPFMCDCHLKWLADYL 452
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4bb (leucine rich repeat containing 4Bb [Source:ZFIN;Acc:ZDB-GENE-091116-44]) HSP 1 Score: 51.6026 bits (122), Expect = 2.125e-6 Identity = 73/326 (22.39%), Postives = 121/326 (37.12%), Query Frame = 1 Query: 442 PVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMG-----DIK-----------------------------LDNQAFNGL-SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEP-ENVNELTKIGWFPSKNS-----SLLPKSWKRFIEVPI-STSPIKYKCKAQNELGNSEIDLIL 1287 P++ S F KL +L +R + + + YA + LR +D E +L A F LV L+ N+G D+ ++ AF+ L +++ L++ ++ L SLP +L P+ L+ + L NP++CNC +LWLS L + + +C +PP + +Y+ L ++ C P IV+ D+ L C +VN LT G + + S+L F V + T P Y C N GN+ +L Sbjct: 129 PLVPSQAFEYLSKLRELWLRNNPIETLPAYAFHRVPSLRRLDLGELRKLSFISEAAFE-GLVNLRFLNLGMCGLKDVPNLTPLVRLEELELSGNQLGLVAQSLPLSLIERNAFDDLKNLEELNLSHNSLHSLPHDLFTPLQQ-------------------------LERVHLNHNPWVCNCDVLWLSWWLKETVP--------DNSTCCARCHAPPGTKGRYIGDLDQRDFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGAYKVRISVLHDGTLNFTNVTMQDTGP--YTCMVTNSAGNTTATAVL 418
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Match: lrrc4bb (leucine rich repeat containing 4Bb [Source:ZFIN;Acc:ZDB-GENE-091116-44]) HSP 1 Score: 50.8322 bits (120), Expect = 3.638e-6 Identity = 73/328 (22.26%), Postives = 121/328 (36.89%), Query Frame = 1 Query: 442 PVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMG-----DIK-------------------------------LDNQAFNGL-SVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEP-ENVNELTKIGWFPSKNS-----SLLPKSWKRFIEVPI-STSPIKYKCKAQNELGNSEIDLIL 1287 P++ S F KL +L +R + + + YA + LR +D E +L A F LV L+ N+G D+ ++ AF+ L +++ L++ ++ L SLP +L P+ L+ + L NP++CNC +LWLS L + + +C +PP + +Y+ L ++ C P IV+ D+ L C +VN LT G + + S+L F V + T P Y C N GN+ +L Sbjct: 129 PLVPSQAFEYLSKLRELWLRNNPIETLPAYAFHRVPSLRRLDLGELRKLSFISEAAFE-GLVNLRFLNLGMCGLKDVPNLTPLVRLEELELSGNQLGVELVAQSLPLSLIERNAFDDLKNLEELNLSHNSLHSLPHDLFTPLQQ-------------------------LERVHLNHNPWVCNCDVLWLSWWLKETVP--------DNSTCCARCHAPPGTKGRYIGDLDQRDFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGAYKVRISVLHDGTLNFTNVTMQDTGP--YTCMVTNSAGNTTATAVL 420
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit3 (slit homolog 3 protein [Source:NCBI gene;Acc:101170687]) HSP 1 Score: 56.9954 bits (136), Expect = 6.494e-8 Identity = 61/203 (30.05%), Postives = 91/203 (44.83%), Query Frame = 1 Query: 307 VRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLS-IQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEIL 909 V CP C SC ++ + C + GLLEIP L E I V I +Q + + +G FS Y+KL + + + ++ I A + L L ++ N + F L + L L N I N L V+T +QN LLSL +Q I+ + L +K+L L NPF+C+C L WL++ L Sbjct: 276 VSVCPPSC-SCNNNIVDCRRKGLLEIPANLPEGI--VEIRLEQNLIKSIPAGAFSPYKKLKRIDLSKNQISDIAADAFNGLRSLTSLVLYGNKITELPKGLFDGLVSLQLLLLNANKI-------NCLRVNTFQDLQNLSLLSLYDNKLQTISKGLFTP-----------------LRSIKTLHLAQNPFMCDCHLKWLADYL 451
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: lrrc4bb (leucine-rich repeat-containing protein 4B [Source:NCBI gene;Acc:101159140]) HSP 1 Score: 51.6026 bits (122), Expect = 2.413e-6 Identity = 59/289 (20.42%), Postives = 103/289 (35.64%), Query Frame = 1 Query: 460 NFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWK-----------RFIEVPISTSPIKYKCKAQNELGNSEIDLIL 1287 N + KL +L + + L +R + L LR + + +IE +AF L S++ L++ ++ L SLP +L P+ L+ + L NP++CNC +LWLS L + + +C +PP L+ +Y+ L + C P IV+ D+ L C +T + WF + + S++ F V + + +Y C N GN+ +L Sbjct: 206 NLTPLVKLEELELSGNQLGIVRPGSFQGLVSLRKLWLMHSRVSVIERNAFDELK----------------------SLEELNLSHNSLHSLPHDLFTPLHQ-------------------------LERVHLNHNPWVCNCDVLWLSWWLKETVPSNTTCCA--------RCHAPPGLKGKYIGELDQSHFPCYAPVIVEPPTDLNVTEGMAAELKCRTG-----TSMTSVNWFTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTG-QYTCMVTNSAGNTTASAVL 433
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: si:cabz01090165.1 (leucine-rich repeat and fibronectin type III domain-containing protein 1-like protein [Source:NCBI gene;Acc:101172994]) HSP 1 Score: 51.2174 bits (121), Expect = 3.180e-6 Identity = 72/301 (23.92%), Postives = 119/301 (39.53%), Query Frame = 1 Query: 352 MLCEKVGLLEIPKLNENIKNVTI---LNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRL----NLVI------------------------LKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVEL---IQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKS-------LELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQ--IDVVYLSYTMVGLNC-MIKEPE 1122 +LC K GLL +P NI T L F+ L +F+ L L++ + +++IR Y + L EL + N +++ S F L +L++ L +N+ DI D A +SV+TLS+ ++ + S+P + + +A + PV +K L NP CNC+L+WL + +DDL C SP +L +Y +T+ ++ C PP I + + + V L C I +PE Sbjct: 41 VLCAKTGLLFVPP---NIDRQTAELRLMDNFIT-TLRHRDFANMSSLIHLTLSRNTISQIRPYTFADLQELHALHMDANRLTVLDDSHFQGLVNLRHLILANNQLHSISEGAFQDFLETLEDLDLSYNNLVDIPWDTIALL-VSVNTLSLDHNLIESVPEGIFSNLHKLARLDMTSNKLKKIPPDPLFLRIPVYAKMKGSPLTALVLSFGGNPLHCNCELVWLRRVT-------------REDDLE-TCASPKDLAGKYFWTIREEEFVCEPPMITRHTSKMFVMEGQEVSLRCKSIGDPE 322
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Match: slit3 (slit homolog 3 protein [Source:NCBI gene;Acc:101170687]) HSP 1 Score: 49.6766 bits (117), Expect = 9.804e-6 Identity = 61/203 (30.05%), Postives = 91/203 (44.83%), Query Frame = 1 Query: 307 VRSCPDQCASCLHDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTL-SIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEIL 909 V CP C SC ++ + C + GLLEIP L E I V I +Q + + +G FS Y+KL + + + ++ I A + L L ++ N + F L + L L N I N L V+T +QN LLSL +Q I+ + L +K+L L NPF+C+C L WL++ L Sbjct: 274 VSVCPPSC-SCNNNIVDCRRKGLLEIPANLPEGI--VEIRLEQNLIKSIPAGAFSPYKKLKRIDLSKNQISDIAADAFNGLRSLTSLVLYGNKITELPKGLFDGLVSLQLLLLNANKI-------NCLRVNTFQDLQNLSLLSLYDNKLQTISKGLFTP-----------------LRSIKTLHLAQNPFMCDCHLKWLADYL 449
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000024613.1 (SMESG000024613.1) HSP 1 Score: 877.47 bits (2266), Expect = 0.000e+0 Identity = 471/471 (100.00%), Postives = 471/471 (100.00%), Query Frame = 1 Query: 253 MTLFHFKISVIIPLLIIAVRSCPDQCASCLHDDMLCEKVGLLEIPKLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGEKPAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIYCETDMDVCXXXXXXXXXXXXXXDTRLIPKS 1665 MTLFHFKISVIIPLLIIAVRSCPDQCASCLHDDMLCEKVGLLEIPKLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHSIRKLLLKSNLLRSLDSKLKPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGEKPAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIYCETDMDVCPFPPPPPPTPPPVPDTRLIPKS Sbjct: 1 MTLFHFKISVIIPLLIIAVRSCPDQCASCLHDDMLCEKVGLLEIPKLNENIKNVTILNQQFMNPVLTSGNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHSIRKLLLKSNLLRSLDSKLKPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGWFPSKNSSLLPKSWKRFIEVPISTSPIKYKCKAQNELGNSEIDLILAWNEGEKPAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIYCETDMDVCPFPPPPPPTPPPVPDTRLIPKS 471
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000021154.1 (SMESG000021154.1) HSP 1 Score: 178.718 bits (452), Expect = 8.389e-49 Identity = 146/465 (31.40%), Postives = 240/465 (51.61%), Query Frame = 1 Query: 253 MTLFHFKISVIIPLLI------IAVRSCPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFSVYRK----LTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGW--FPSKN--SSLLPKSWKRFIEVPISTSPI--KYKCKAQNELGNSEIDLILAW----NEGEKPAIVLEN---STFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIY 1575 + ++ ++S I+PL + + ++ CP+ C CL + CE GL IP +L E V ++ +F L+ NFS + K + LSIR SN+ IR +S L +DFSEN +L IE+ AF L L LKLD +G+++ AF GL V +L+I SHL +LP LI+P++ +R L L +N L SL SK + + L L+L NPFIC+C +LWL L R + + + + +PKC P L QY+Y + + NC PP + +I+V + S L C E+ KI W SK +LLP S E+ I+ +Y C + GN+ + + W N ++P ++ + ++ + ++++ + + ++L E++ +I GT +IT+++F+L Y ++ I KK +L+ + +YE G YSD++ Y Sbjct: 8 LQIYFIRVSFILPLFMYDSLTAVFIKPCPNVCTPCLEHAITCENGGLDGIPTELYEETTRVILVGHKFSQTFLSRQNFSKFTKPKYSIEQLSIRRSNIQIIRSQTFYDVSGLDFLDFSENLKLYIENRAFDNLKLKHLKLDFIGNLEFSEDAFQGLLVASLTIAKSHLQALPYRLIEPLSRELRSLFLSNNKLTSLSSKFESLFRQLTILDLHGNPFICSCNMLWLGVTLKWRQNYYRSNTNSFSEPQFPKCDKPYYLLNQYLYEIPETEFNCRPPKLDRIEVQFKSQQSAVLKCAASL-ESKRAPMKISWLYLSSKEYVPNLLPSSKSNEAEIEITQKHYIDQYFCSVSSAAGNASVKVNFNWPTVTNIRQRPNNSIDEYFVTKPTWKTNYYQENYFFREQYTLLELLGSILGTFIITILIFILIYKFYFFKT----IKMKKEQLKKSGHVTYETGFYSDSQTY 467
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000079433.1 (SMESG000079433.1) HSP 1 Score: 174.481 bits (441), Expect = 2.912e-47 Identity = 143/447 (31.99%), Postives = 228/447 (51.01%), Query Frame = 1 Query: 316 CPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTS----GNFSVYRKLTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRIS-GTKL-IDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNELTKIGW------FPSKNSSLL--PKSWKRFIEVPI--STSPIKYKCKAQNELGNSEIDLILAWNEGEKPAIVLENSTFKFEETFIKQS-------FLWEKVFSLFEMICAIFGTLVITVILFLL---FCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIY 1575 CP C C +D + C GLL IP ++E+ +T++ +F++ L+ G F + LSIR SN+ I + LS L N+D SEN +II + AF L L LKLD + + L+ AF+GL+V +LS++NS L +L +L++PI++++R L L +N + LD K +P++ L L+L NPF C CKL+WLS L R+ G +L + Q +P C P ++ +Y++ + + +C PP++ ID+ + + +V L C K P + ++ W F K+S L P I S+S Y+C A++ GN+ I + + W LEN+T + QS F + + F+L EM+ A+ GT +T+ +FLL FC + KK L+ Y YE +YSD++ Y Sbjct: 25 CPKVCIICFNDHLSCTTGGLLSIPTNIHESTTKITLIGHEFLSSSLSKSNFSGFFKPKYSIEQLSIRQSNIKVIEKDTFYDLSGLDNLDLSENKAIIIRNKAFNNLKLKHLKLDQIQGLVLERGAFDGLAVTSLSMKNSSLKTLSFDLMRPISNNLRSLFLSNNHISELDQKFEPLITQLSHLDLTGNPFQCTCKLVWLSRALEKRMGLGLELEFSNSGQYVNFPLCAGPAHVKDKYIHNITEAEFSCEPPSLDVIDIQFENLDIVKLKCSAKLPFKAAPI-QVYWQEISDPFSLKDSQLEKNPNDETNLAVTVIRKSSSVNLYQCLAKSSSGNATIRVTINWPPVINRTKPLENNTPNSNNNWFGQSNKQTEKNFFFREQFTLLEMLGAVMGTFTVTLTIFLLLYRFCVKATSKV------KKANSLKKSGYSIYEPAIYSDSQTY 464
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000001555.1 (SMESG000001555.1) HSP 1 Score: 167.548 bits (423), Expect = 1.844e-44 Identity = 142/454 (31.28%), Postives = 227/454 (50.00%), Query Frame = 1 Query: 316 CPDQCASCLHDDMLCEKVGLLEIP-KLNENIKNVTILNQQFMNPVLTSGNFS--VYRK--LTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEIL---------NNRISGTKLIDSYNQDDLYPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMIKEPENVNEL-TKIGWFPSKNSSLLPKSWKRFIE----------------VPISTSPIKY-----------KCKAQNELGNSEIDLILAW---------NEGEKPAIVLENS--TFKFE-ETFIKQSFLWEKVFSLFEMICAIFGTLVITVILFLLFCCCYVERSHLLLIGKKKRK 1515 CP C+ CL + C L IP +L + +T+ Q +PVL+S NF+ Y K + LSIR ++ + + S L L+ +D SEN L I S+F L+L +LKLD++G + L +F+ LS ++LS++ S L SL + QPI+HS++ L +++N ++ LD +P+ L+S+ L+DN FIC C LLWLS+ L NR S K DS + + +PKCV P LR + + T+ + NC P I QI++ LS ++C IK E +++ TK+ W K K ++R E + +S IK+ C A+N+ G S + + ++W ++ P E T ++ T ++S+ + K ++L EM AI GT +ITV++FL+F Y + + GK K Sbjct: 28 CPMHCSICLPSHISCTTGSLTSIPNQLQPKTETITLSGQLQFHPVLSSANFTDLAYPKYQIHTLSIRSCSIYELSSHTFSQLVMLKILDLSENQRLTIMSSSFSGLHLKVLKLDDIGKLMLSPDSFSDLSTESLSMKASRLQSLNFNIFQPISHSLKHLNIENNQIKILDQSFEPLFYRLESVNLKDNTFICYCDLLWLSKALRSKLSFYKSQNRFSDGK-ADSNSDVNNFPKCVGPTYLRDRQLQTISESEFNCQVPQIAQIEIDLLSVFGGMMSCSIKPEEKGHKIPTKVFW--EKQHPQNGKVFQRVYEKSQNAVDGFSLLENNGIAEFSSKIKFDSDRNKNQENFNCVAENKAGRSLVSVQISWPKFNNSLDSSQPNSPTTESEKKQPTDHYQWNTPNQKSYFFTKQYTLLEMTAAIAGTFMITVVIFLVFYKFYFRKRNGYKSGKPSMK 478
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000018621.1 (SMESG000018621.1) HSP 1 Score: 144.05 bits (362), Expect = 1.469e-36 Identity = 133/447 (29.75%), Postives = 222/447 (49.66%), Query Frame = 1 Query: 316 CPDQCASCLHDDMLCEKVGLLEIPK-LNENIKNVTILNQQFMNPVLTSGNFSVYRK----LTDLSIRLSNLNRIRQYALSALSELRNVDFSENTELIIEHSAFFRLNLVILKLDNMGDIKLDNQAFNGLSVDTLSIQNSHLLSLPVELIQPIAHXXXXXXXXXXXXXXXXXXXXPVLIGLKSLELQDNPFICNCKLLWLSEILNNRISGTKLIDSYNQDDL--YPKCVSPPELRKQYVYTLVKKLKNCIPPTIVQIDVVYLSYTMVGLNCMI-----KEPENVNELTKI------GWFPSKNSSLLPKSWKRFIEVPI-----STSPIKYKCKAQNELGNSEIDLILAWNEGEK---PAIVLENSTFKFEETFIKQSFLWEKVFSLFEMICAIFGTLVITVIL-FLLFCCCYVERSHLLLIGKKKRKLQTKSYPSYERGVYSDTRIY 1575 C C +C+ D + C K G E+P+ +++ K +++QQF N L+ N + L L+IR SN+ I+ S L+ LR +D + N L I+ +F L L +LKLDN ++K AF L+V++L + S + LP +L++PI ++KL + +N L SLD + + L++L LQ N F C+C + WL+ + R + K D++ +P C P + ++++ + L NC PP + Q+ + + S T L+C + P VN T I F NS P + R + V + S ++C A+N GN+ + ++W EK P + ST + + ++ ++K F+L EM A+FGT IT+IL F+++ ++ RS +K L Y +YE VYSD++ Y Sbjct: 25 CGKFCDACVEDSISCTKPGFKEMPQQMSKTTKRFILISQQFTNNFLSRENLTKISPPNVFLEYLTIRKSNIKLIKPMTFSDLTVLRALDLTYNNNLFIDSGSFSGLKLKLLKLDNNDNLKFSINAFVDLTVESLHMSQSSIFDLPYDLLKPILPFLKKLFINNNNLISLDPRFQIPFKNLQTLYLQGNSFDCSCSMKWLTAVYVYRTTNGKYNKGTFTDEIQSFPTCKEPKYMEGKHMHEIPLSLFNCDPPNLTQLKIDFQSATETELSCSAVQKVDQAPMTVNWFTDIINGIGEKMFSILNSKSNPTT-DRNVHVETVLIQKNNSTDSFQCIAKNLNGNATAIVRISWPPSEKFPNPNRNVYQSTIDSWQKSEEDNYFFQKRFTLLEMFGAVFGTFAITLILFFMIYKFVFINRS-----TDRKAILPPNGYTTYEAAVYSDSQTY 465 The following BLAST results are available for this feature:
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 1
BLAST of Ig-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 4
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002228 ID=SMED30002228|Name=Ig-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1932bpback to top protein sequence of SMED30002228-orf-1 >SMED30002228-orf-1 ID=SMED30002228-orf-1|Name=SMED30002228-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=489bp MKILLTDNRMDIFYQMTLFHFKISVIIPLLIIAVRSCPDQCASCLHDDMLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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