4Fe-4S ferredoxin-type domain-containing protein

Query:  125 RKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTF 2218
            +  NT      + G+P  + +N+  + +++ ++ FLRK AW+YG LA L     I + +       E SE   S ++     E  +  F     N     + M DE L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  GS L  +S    + TI NV  ES  LW+H  +S  + +  F   + H      +  ++ + T+MI  VP +  D  +I +HF EAYP     +V   Y+V  LI L  Q+  A     F Y        +V +  + C R+C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++   A RVR+DY Y    C  +  +  SS +  + S  W VT AP PKDI+W++L  R + WW   I IN F+  +   L+TPA+ +N  +    +  +EKL NP+V QF PS+++   + ++PLIVY+S  L AHWT+++QN+ +++K +  LV  V+ILPS+GL S+   ++WLF        +I+++C+F+ D GA F NY+ITA+ +GT +ELLRLG LF Y+ +   SRS  E   I K+   DFQFG  YAW + +FSVV AYS+  PII PFGL YL +KHL DRYN+ +   P+ ++  +H  A        +L    +  +  LR G+   ++I      ++ +++ F
Sbjct:   24 QSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALL-----IHNDSLTSLIYGEQSEKT-SPSETSLEMERRDKGFCSWFFNS----ITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFART-TIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLF-YTAKAKKTGKVMIRIHPCARLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQ--CGVQPQQ--SSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAF 701          

Query:  101 DRYNS---YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELE-HDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR---SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRG 2155
            DR N    Y   KN+T      + GIP  + I+V  +  LI +F  +R++ W+YG +A + +                 SE+ F      +S    +   +      L    +++D+ + + CG DA+ Y  FQR++I ++ V+  LSL +I+P+NL G  L  +   F   TIAN+  ++  LW+H   ++ ++         H  +I +K +     T+ I  +P +   E  +  HFR+AYP+   + VQ+ Y V+ LI L  +K   E++L + Y  L+     R  + P  CG+ C    CC+   C   D I +YT    RL    T E+ + +  + L + FVTF+    A  + +D+      C +   KG    SS+S +L +  WTVTFA  P+DI W+NL  +G RWWL  + IN  + + +  L+TP++ L+  +    ++ +  LNNP+++QF P+L++   SA++P IVY+S  L +HWTK+ +N  +M K++  L+  VLILPSLGL S+    +WLF   +++  +I+ EC+F+ D GA F NY+I ++FIG  +ELLRL  L +YT +   +++ A+   + ++  + ++FG  YAW L +F+V+ AYS+  PII PFGL Y+LLKH+VDR+NL  V +P+ +   +H  A        +L    +  +  LR G
Sbjct:   25 DRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSE---------------ADSESRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARKE-TVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKEKKKTEKSLTY-YTNLQVKTGQRTLINPKPCGQFC----CCEVLGCEWEDAISYYTRMKDRLLERITEEERH-VQDQPLGMAFVTFQEKSMATYILKDF--NACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLF-DKTSSEASIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIVAYSITCPIIAPFGLIYILLKHMVDRHNLYFVYLPAKLEKGIHFAAVNQALAAPILCLFWLYFFSFLRLG 691          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASK---ENINLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL 2212
            Y  R  +T      + G+P  + ++ + +  L+ LF  LRK AW+YG LA +     +      +  +   + A+  D+     +    + ++ F ++     + L    ++ D+ ++ +CG DAV Y  FQR++I ++ V+ VLS+ I++P+N  G  L +N+  F   TIAN+   +  LW+H + +  ++L   +   +H + + +K  +    T+ IN + +++ +   I +HF EAYP+   ++ +  Y V+ L+ L  ++  AE    +       +N    + P  CG +C    CC  + C  ++ IE+YT    +L   +  EK   +N K L + FVTF N      + +D+ + +   C  +     SS S  L+  +WTV++AP P++I W++L  RG+ WWL  +VIN+ + I++  L+TPA+ +   +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF     A   I++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + +   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYNL +  +P+ +   +H+ A   +    +L    +  +  +R G     S+  F+  V+ +++
Sbjct:   24 YSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERDRVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGI-SKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCGHLC----CCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEK-VNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVI 723          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASK---ENINLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL 2212
            Y  R  +T      + G+P  + ++ + +  L+ LF  LRK AW+YG LA +     +      +  +   + A+  D+     +    + ++ F ++     + L    ++ D+ ++ +CG DAV Y  FQR++I ++ V+ VLS+ I++P+N  G  L +N+  F   TIAN+   +  LW+H + +  ++L   +   +H + + +K  +    T+ IN + +++ +   I +HF EAYP+   ++ +  Y V+ L+ L  ++  AE    +       +N    + P  CG +C    CC  + C  ++ IE+YT    +L   +  EK   +N K L + FVTF N      + +D+ + +   C  +     SS S  L+  +WTV++AP P++I W++L  RG+ WWL  +VIN+ + I++  L+TPA+ +   +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF     A   I++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + +   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYNL +  +P+ +   +H+ A   +    +L    +  +  +R G     S+  F+  V+ +++
Sbjct:   24 YSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERDRVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGI-SKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCGHLC----CCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEK-VNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVI 723          

Query:  230 LRKKAWNYGNLAWLGKPLNIEH-VAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL 2212
            LRK AW+YG LA +    ++   +      R E   ++ S  D    ++N          + L    ++ D+ ++ +CG DAV Y  FQR++I ++ V+ VLS+ I++P+N  G  L +N+  F   TIAN+   +  LW+H + +  ++L   +   +H + + +K  +    T+ IN + +++ +   I +HF EAYP+   ++ +  Y V+ L+ L  ++  AE    +       +N    + P  CG +C    CC  + C  ++ IE+YT    +L   +  EK   +N K L + FVTF N      + +D+ + +   C  +     SS S  L+  +WTV++AP P++I W++L  RG+ WWL  +VIN+ + I++  L+TPA+ +   +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF     A   I++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + +   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYNL +  +P+ +   +H+ A   +    +L    +  +  +R G     S+  F+  V+ +++
Sbjct:    4 LRKVAWDYGRLALVTDADSVASAMHGDSHDRYERLTSVSSSVD-FDQRDN-------GFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGI-SKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCGHLC----CCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEK-VNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVI 652          

Query:  131 NNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLG----------------------KPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPX--XXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCF------LAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSK 2281
            N T   +TAY GIP+ + +N + + +LI LF  LR +A ++G LA +                       +P     V+PR  + S+       D+ P++  +      +E L   + + +K+  E +    G DAV Y  FQ++L+A+++++ ++SL II+P+           + + F   T+AN+  +SP+LW+H  +++ ++  V  I  +      FK  +  + T+MI+N+ +   ++ ++  + +E +P +    V + Y +S L     +     EA  +C      D   VK  P +C              C   +  E+Y  E  +L+      +++ +N + L I F+T   + +A  +   +    Y                     W + FAP P D+ W+NL+     W+L    +N  + +V+  LSTPA+ +++ N+  + +  E   +PLVA F P+L++  +SA+MP+IV  SD+   H+T++ QN ++M K F  L++ ++ILPSLGL S   L++W F+       T +W+CIF+ D G+ + NYIITA+FIGTALELLR  EL +Y      ++S+AE   I K++L +F FG  YAWT  +F++   YSV  P+I PF + Y+ LKH VDR+NL     PS   N +     ++    + +T+ +V + V        ++++ CF      +A  L L+++   T+  + F MS +K   +++
Sbjct:   17 NRTSFFTTAYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQG----VPDSTPLSPIQP-----EEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMANLSPDSPWLWVHTIITILYIPLVVLIMRRASGRNAFK--KAATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFERVHEARLYCEHHRNRDTLMVK--PEMCS-------------CKKENAYEYYQREERKLSGDVARLRASTMN-EPLDIAFITVSTVQEAQNIVTHFTPGTY-------------------RQWHLVFAPSPDDLFWENLNVNKSHWYLKFFCVNAVLFLVLFFLSTPAMVVSLLNSRPWVKETEGKISPLVADFLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLNQ-----TDRWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPS---NMISRKGGKIHSTAVTMTKFSVVILVL-------VMAMICFFRGDNGMARFLLLIISLAITLTLFTF-MSPIKRCAATR 701          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLT-FGRTVKR 2236
            + G+P  + INVV + IL+ +F  LRK AW+YG LA L K  ++  +   ++S  E + +  S     +  E  ++ F   L ++      M DE ++ +CG DAV Y  FQR++I ++ V+ +LSLTII+P+NL G+ L  N   F   T+ NVP ++ FLW+H   +L + +      + H + ++++  E+ + T+MI ++P E  D  +I +H  EAYPS     +   + V  L+ L +++  A +   + +      N R+ +  + C ++   C  C  +K   +D  ++Y+    +LT+ F  EK N I+ K+L I FVTF +      + +DY      C +K  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  I++N+ + +++  L+TPA+ +N  +    +  +E L NP++ QF P+L++   S ++P IVY+S     HWT++ +N   M+K F +LV  V+ILPSLGL+S+    +WLF         +K++C+F+ D GA F NY+IT+S IGTA+ELLR+  L +Y+++   ++S+AE   +  S  ++FQFG+ YAWT+ +FSV   YS+  P+I PFGL YL+LKH+VDRYN+ +   P+ ++  +H  A   + V  +L    +  +  LR G    +++  F+  +  +  + FG  +K+
Sbjct:   48 FGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDSLTSLFYGEQSEKEKTPSDSS----PSDSETKDMGFCSWLTSLY----HMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLY-FTTKAQKNGRIMIKTHPCAQI-FCCDICGFEK---VDAEQYYSELEEKLTDEFNAEK-NWISMKRLGIAFVTFRDERMTAVIVKDYSRAR--CRHKPQQ--SSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVAPILCMFWLLFFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCMKK 723          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLT-FGRTVKR 2236
            + G+P  + INVV + IL+ +F  LRK AW+YG LA L K  ++  +   ++S  E + +  S     +  E  ++ F   L ++      M DE ++ +CG DAV Y  FQR++I ++ V+ +LSLTII+P+NL G+ L  N   F   T+ NVP ++ FLW+H   +L + +      + H + ++++  E+ + T+MI ++P E  D  +I +H  EAYPS     +   + V  L+ L +++  A +   + +      N R+ +  + C ++   C  C  +K   +D  ++Y+    +LT+ F  EK N I+ K+L I FVTF +      + +DY      C ++  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  I++N+ + +++  L+TPA+ +N  +    +  +E L NP++ QF P+L++   S ++P IVY+S     HWT++ +N   M+K F +LV  V+ILPSLGL+S+    +WLF         +K++C+F+ D GA F NY+IT+S IGTA+ELLR+  L +Y+++   ++S+AE   +  S  ++FQFG+ YAWT+ +FSV   YS+  P+I PFGL YL+LKH+VDRYN+ +   P+ ++  +H  A   + V  +L    +  +  LR G    +++  F+  +  +  + FG  +K+
Sbjct:   61 FGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDSLTSLFYGEQSEKEKTPSDSS----PSDSETKDMGFCSWLTSL----YHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLY-FTTKAQKNGRIMIKTHPCAQI-FCCDICGFEK---VDAEQYYSELEEKLTDEFNAEK-NWISMKRLGIAFVTFRDERMTAVIVKDYSRAR--CRHRPQQ--SSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVAPILCMFWLLFFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCLKK 736          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLT-FGRTVKR 2236
            + G+P  + INVV + IL+ +F  LRK AW+YG LA L K  ++  +   ++S  E + +  S     +  E  ++ F   L ++      M DE ++ +CG DAV Y  FQR++I ++ V+ +LSLTII+P+NL G+ L +        T+ NVP ++ FLW+H   +L + +      + H + ++++  E+ + T+MI ++P E  D  +I +H  EAYPS     +   + V  L+ L +++  A +   + +      N R+ +  + C ++   C  C  +K   +D  ++Y+    +LT+ F  EK N I+ K+L I FVTF +      + +DY      C +K  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  I++N+ + +++  L+TPA+ +N  +    +  +E L NP++ QF P+L++   S ++P IVY+S     HWT++ +N   M+K F +LV  V+ILPSLGL+S+    +WLF         +K++C+F+ D GA F NY+IT+S IGTA+ELLR+  L +Y+++   ++S+AE   +  S  ++FQFG+ YAWT+ +FSV   YS+  P+I PFGL YL+LKH+VDRYN+ +   P+ ++  +H  A   + V  +L    +  +  LR G    +++  F+  +  +  + FG  +K+
Sbjct:   48 FGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDSLTSLFYGEQSEKEKTPSDSS----PSDSETKDMGFCSWLTSL----YHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLENFGRT----TVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLY-FTTKAQKNGRIMIKTHPCAQI-FCCDICGFEK---VDAEQYYSELEEKLTDEFNAEK-NWISMKRLGIAFVTFRDERMTAVIVKDYSRAR--CRHKPQQ--SSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVAPILCMFWLLFFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCMKK 719          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPR-KESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXX-------XXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTV 2230
            Y  R  +T      + G+P  + ++ + + +L+ +F FLRK AW+YG LA +    ++        +SR E   ++ S  D    ++N        L + L    ++ D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ I++P+N  G  L          +  F   T+ N+   +  LW+H   +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   +  ++ Y V+ L+SL +++  AE + +F  + +  ++    + P  CG +C    CC  K C   + + +YT    +L   +  E+   +N K L + FVTF+N   A  + +D+   Q + C  +     S +S QL++ +WTV++AP P+++ W++L   G  WW+   VIN F+ +++  L+TPA+ ++  +    ++ +E LNNP+V QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF        TI++ C+F+ D GA F NY+I ++FIG A++LLR+    MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R+G     S+  F+  ++ +++     V
Sbjct:   19 YSGRIRSTVLQGLPFGGVPTVLALDFMCFLVLLCVFSFLRKVAWDYGRLALVSDADSVASAMQTPADSRYERLTSVSSSVD-FDQRDN-------GLCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDQLVETGNFENNNAYSFGRTTVVNLKSGNHLLWLHTIFAFFYLLLTVYSMRRHTSKMHYKEDDLVKRTLFISGI-AKYAEESEIKQHFEKAYENCVVLDARICYNVAKLMSLESERKKAERSKKFYTDLMSREHIPTMINPKPCGHLC----CCIIKGCEQEEAVNYYTKLEAKLKEEYRKEREK-VNTKPLGMAFVTFQNEAMAALILKDFNACQCHGCHCRRQPKSSPFSSQLHTYNWTVSYAPDPQNVYWEHLSISGLNWWVRCFVINCFLFLLLFFLTTPAIIISTMDKFNVTKPVEYLNNPIVTQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLDEATIRFRCVFLPDNGAFFVNYVIASAFIGNAMDLLRIPYFLMYMIRLCLARSAAERRNVKKHQAYEFQFGAAYAWMMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCIFWLLFFSTVRQGFGAPTSMFTFVVLIITIIICLSHIV 718          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLT-------FKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXX-------XXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTV 2230
            Y  R  +T      + G+P  + ++ + + +L+ +F FLRK AW+YG LA +    + +    +   R +  E + S     A      LT       F ++   L + L    ++ D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ I++P+N  G  L          +  F   T+ N+   +  LW+H   +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   +  ++ Y V+ L+SL +++  AE + +F  + +  ++    + P  CG +C    CC  K C   + + +YT    +L   +  E+   +N K L + FVTF+N   A  + +D+   Q + C  +     S +S QL++ +WTV++AP P+++ W++L   G  WW+   VIN F+ +++  L+TPA+ ++  +    ++ +E LNNP+V QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF        TI++ C+F+ D GA F NY+I ++FIG A++LLR+    MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R+G     S+  F+  ++ +++     V
Sbjct:   19 YSGRIRSTVLQGLPFGGVPTVLALDFMCFLVLLCVFSFLRKVAWDYGRLALVS---DADSRRNKHYQRLDEQEYVASAMQTPADSRYERLTSVSSSVDFDQRDNGLCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDQLVETGNFENNNAYSFGRTTVVNLKSGNHLLWLHTIFAFFYLLLTVYSMRRHTSKMHYKEDDLVKRTLFISGI-AKYAEESEIKQHFEKAYENCVVLDARICYNVAKLMSLESERKKAERSKKFYTDLMSREHIPTMINPKPCGHLC----CCIIKGCEQEEAVNYYTKLEAKLKEEYRKEREK-VNTKPLGMAFVTFQNEAMAALILKDFNACQCHGCHCRRQPKSSPFSSQLHTYNWTVSYAPDPQNVYWEHLSISGLNWWVRCFVINCFLFLLLFFLTTPAIIISTMDKFNVTKPVEYLNNPIVTQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLDEATIRFRCVFLPDNGAFFVNYVIASAFIGNAMDLLRIPYFLMYMIRLCLARSAAERRNVKKHQAYEFQFGAAYAWMMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCIFWLLFFSTVRQGFGAPTSMFTFVVLIITIIICLSHIV 732          

Query:   89 TLQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEA-LQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL-TFGRTVKR 2236
            T QC + +S+     +T      + GIP  + IN +A+ +L+ +F  LRK AW+YG LA L    ++  +   + S  E S    S ++  AS +++ L       + L    +M DE ++ +CGSDA+ Y  +QR+L+ ++  +  +S+ II+P+N  G  L  + + F   TI NVP +  FLW+H   +L + LF       H +++ +K  ++ + T+MI  +P+E  D  +  +HF EAYPS     VQ  Y+V  L+ L  ++  A +  + F     +    ++K+ P  C R+C  C CC  ++   ++  ++Y     RLT+ FT E+ N I  K+L   FVTF++      + +DY   N L  +++ + +SS +  L S  W V +AP P DI+W+NL   G  WW   + +N+ + +++  L+TPAV ++  +    +  +EKL NP++ QF P+ ++ + S  +P +VY+S     HWT++++N   M+K +  LV  V++LPSLGL S+    +WLF  +      IK++C+F+ + GA F NY+ITAS IGTA+ELLR   L +Y  +   +R+  +   + ++  ++FQFG+ YAWT  +FSVV AYS+  P+I PFGL Y+LLKH+ DRYN+ +  +P+ +   +H  AA  M    VL    +  +  LR G+T  +++  F   +  LL  TFG  +K+
Sbjct:   24 TEQCYKAHSH-----STVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLIDNDSLTSLFYGEPSEKEKSPCEISPSE--ASTKDVGLC------SWLSSIYQMKDEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLC-PCDCCGFQQ---VEAEQYYGELEERLTDEFTAER-NRITLKRLGAVFVTFQDERMTAVIIKDY---NRLPCHRAPQ-QSSVTPLLKSHKWKVHYAPAPSDIIWENLAVSGALWWFRFLALNLLLFVLLFFLTTPAVIVSTMDRFNVTYPVEKLRNPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQCVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAAAYQMLAAPVLCIFWLLFFSVLRLGSTHPVTLFTFAVLLFCLLFSTFGLCLKK 717          

Query:   89 TLQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSE-----HSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEA-LQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL-TFGRTVKR 2236
            T QC + +S+     +T      + GIP  + IN +A+ +L+ +F  LRK AW+YG LA L    N  H   R+ +  +     + E    +  P     +   T    L + L    +M DE ++ +CGSDA+ Y  +QR+L+ ++  +  +S+ II+P+N  G  L  + + F   TI NVP +  FLW+H   +L + LF       H +++ +K  ++ + T+MI  +P+E  D  +  +HF EAYPS     VQ  Y+V  L+ L  ++  A +  + F     +    ++K+ P  C R+C  C CC  ++   ++  ++Y     RLT+ FT E+ N I  K+L   FVTF++      + +DY   N L  +++ + +SS +  L S  W V +AP P DI+W+NL   G  WW   + +N+ + +++  L+TPAV ++  +    +  +EKL NP++ QF P+ ++ + S  +P +VY+S     HWT++++N   M+K +  LV  V++LPSLGL S+    +WLF  +      IK++C+F+ + GA F NY+ITAS IGTA+ELLR   L +Y  +   +R+  +   + ++  ++FQFG+ YAWT  +FSVV AYS+  P+I PFGL Y+LLKH+ DRYN+ +  +P+ +   +H  AA  M    VL    +  +  LR G+T  +++  F   +  LL  TFG  +K+
Sbjct:   24 TEQCYKAHSH-----STVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLID--NDSHALQRRWTSYDLTSLFYGEPSEKEKSPCEISPSEASTKDVGLCSWLSSIYQMKDEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLC-PCDCCGFQQ---VEAEQYYGELEERLTDEFTAER-NRITLKRLGAVFVTFQDERMTAVIIKDY---NRLPCHRAPQ-QSSVTPLLKSHKWKVHYAPAPSDIIWENLAVSGALWWFRFLALNLLLFVLLFFLTTPAVIVSTMDRFNVTYPVEKLRNPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQCVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAAAYQMLAAPVLCIFWLLFFSVLRLGSTHPVTLFTFAVLLFCLLFSTFGLCLKK 728          

Query:   89 TLQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEA-LQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL-TFGRTVKR 2236
            T QC + +S+     +T      + GIP  + IN +A+ +L+ +F  LRK AW+YG LA L    ++  +   + S  E S    S ++  ++K+  N  F         LF +  DE ++ +CGSDA+ Y  +QR+L+ ++  +  +S+ II+P+N  G  L  + + F   TI NVP +  FLW+H   +L + LF       H +++ +K  ++ + T+MI  +P+E  D  +  +HF EAYPS     VQ  Y+V  L+ L  ++  A +  + F     +    ++K+ P  C R+C  C CC  ++   ++  ++Y     RLT+ FT E+ N I  K+L   FVTF++      + +DY   N L  +++ + +SS +  L S  W V +AP P DI+W+NL   G  WW   + +N+ + +++  L+TPAV ++  +    +  +EKL NP++ QF P+ ++ + S  +P +VY+S     HWT++++N   M+K +  LV  V++LPSLGL S+    +WLF  +      IK++C+F+ + GA F NY+ITAS IGTA+ELLR   L +Y  +   +R+  +   + ++  ++FQFG+ YAWT  +FSVV AYS+  P+I PFGL Y+LLKH+ DRYN+ +  +P+ +   +H  AA  M    VL    +  +  LR G+T  +++  F   +  LL  TFG  +K+
Sbjct:   24 TEQCYKAHSH-----STVLQGLPFGGIPTVLAINFLAWLVLLLIFSCLRKAAWDYGRLALLIDNDSLTSLFYGEPSEKEKSPCEISPSE-ASTKDVTNCGF---------LFFR--DEEIQSKCGSDAITYLSYQRHLLVVLLAVCCISVAIILPVNFSGDMLGDSPAQFGRTTIVNVPTKDRFLWLHSVFALVYFLFSVLCMRHHTSSLHYKEDDKVARTLMITKIPSEISDASLFTKHFHEAYPSCTVTDVQFCYDVRHLMKLDKERRRAMKGRMYFAGRAQKEGKIQIKIHP--CARLC-PCDCCGFQQ---VEAEQYYGELEERLTDEFTAER-NRITLKRLGAVFVTFQDERMTAVIIKDY---NRLPCHRAPQ-QSSVTPLLKSHKWKVHYAPAPSDIIWENLAVSGALWWFRFLALNLLLFVLLFFLTTPAVIVSTMDRFNVTYPVEKLRNPVITQFLPTFLLWMFSVCLPFLVYYSAFFECHWTRSSENQHTMHKCYFFLVFMVIVLPSLGLTSLNLFFRWLFDIHFLDEANIKFQCVFLPNNGAFFVNYVITASLIGTAMELLRFPGLTVYAARLCLARTEPDRLHVKRNQAYEFQFGLEYAWTTCVFSVVMAYSITCPVIVPFGLIYMLLKHMTDRYNIYYAYIPTKLSPGLHKAAAYQMLAAPVLCIFWLLFFSVLRLGSTHPVTLFTFAVLLFCLLFSTFGLCLKK 713          

Query:  131 NNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY---MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTT 2161
             +T      + GIP  + ++V  +  L+  F  +R+  W+YG +A +    +  H   R+ S S   E +  D        +   TF+            MNDE +  RCG DA  Y  FQR++I ++ +  +LS+ +I+P+NL G+ L  +   F   TIAN+      LW+H  V++ +++        HL+ I +K +     T+ I  +P    D+  +  HF EAYPS    +V + Y+V+ LI L  ++  AE+ L +    L     RV + P  CG+ C    CC  + C   D IE+YT     +   +   K   +    L I FVTF +   +  + +D+       Y C +++    S+YS QL +  W VT+A  P++I W NL  +G +WW   + IN  + IV+  L+TP++ ++  +    ++ ++ LNNP+++QF P+L++   SA++P IVY+S  L AHWTK+ +N  +M+K++  L+  VLILPSLGL S+    +WLF         ++ EC+F+ D GA F NY+I ++F+G  +EL+RL  L +YT++   ++S AE   I ++  ++++FG  YAW L +F+VV AYS+  PII PFGL YLLLKH+VDR+NL +  +P+ +   +H +A +      +L    +  Y  LR G T
Sbjct:   37 GSTVLQGVTFGGIPTVLVLDVACFMFLLLAFAIIRRHFWDYGRVALVYDADSSPHSRYRRLSSSSGGEELERDNGFCYWMTS---TFQ------------MNDEDIYDRCGEDATHYLSFQRHIICLLIIASILSVGVILPVNLSGNLLDKDPLSFGRTTIANLQHHDRLLWLHTVVAVVYLILTVVFMRHHLSAIKYKEENTVKQTLFITGLPRN-VDKETVRLHFSEAYPSCQVEEVNLCYDVADLIRLSKERKKAEKNLAYFTNLLNKTGRRVLINPKPCGQFC----CCVVRGCEREDAIEYYTRVRDGVMEEYA-RKQEVVCDIPLGIVFVTFADKSMSTLILKDFNAVKCSGYRCAHETQP--SAYSKQLGTSRWGVTYATYPENICWGNLSLQGVKWWARCLGINFCLFIVLFFLTTPSIIISTMDKFNVTKPIQALNNPVISQFFPTLMLWSFSALLPTIVYYSTLLEAHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFDRALDLQGPVRLECVFLPDQGAFFVNYVIASAFVGNGMELMRLPGLILYTIRMIMAKSAAERRNIKQNQAFEYEFGAMYAWMLCVFTVVMAYSITCPIIVPFGLIYLLLKHMVDRHNLYYAYLPTKLDKKIHFSAVRQALTAPILCLMWLFFYSLLRMGFT 693          

Query:  131 NNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY---MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTT 2161
             +T      + GIP  + ++V  +  L+  F  +R+  W+YG +A +    +  H   R+ S S   E +  D                         V  NDE +  RCG DA  Y  FQR++I ++ +  +LS+ +I+P+NL G+ L  +   F   TIAN+      LW+H  V++ +++        HL+ I +K +     T+ I  +P    D+  +  HF EAYPS    +V + Y+V+ LI L  ++  AE+ L +    L     RV + P  CG+ C    CC  + C   D IE+YT     +   +   K   +    L I FVTF +   +  + +D+       Y C +++    S+YS QL +  W VT+A  P++I W NL  +G +WW   + IN  + IV+  L+TP++ ++  +    ++ ++ LNNP+++QF P+L++   SA++P IVY+S  L AHWTK+ +N  +M+K++  L+  VLILPSLGL S+    +WLF         ++ EC+F+ D GA F NY+I ++F+G  +EL+RL  L +YT++   ++S AE   I ++  ++++FG  YAW L +F+VV AYS+  PII PFGL YLLLKH+VDR+NL +  +P+ +   +H +A +      +L    +  Y  LR G T
Sbjct:   37 GSTVLQGVTFGGIPTVLVLDVACFMFLLLAFAIIRRHFWDYGRVALVYDADSSPHSRYRRLSSSSGGEELERDN------------------------VSTNDEDIYDRCGEDATHYLSFQRHIICLLIIASILSVGVILPVNLSGNLLDKDPLSFGRTTIANLQHHDRLLWLHTVVAVVYLILTVVFMRHHLSAIKYKEENTVKQTLFITGLPRN-VDKETVRLHFSEAYPSCQVEEVNLCYDVADLIRLSKERKKAEKNLAYFTNLLNKTGRRVLINPKPCGQFC----CCVVRGCEREDAIEYYTRVRDGVMEEYA-RKQEVVCDIPLGIVFVTFADKSMSTLILKDFNAVKCSGYRCAHETQP--SAYSKQLGTSRWGVTYATYPENICWGNLSLQGVKWWARCLGINFCLFIVLFFLTTPSIIISTMDKFNVTKPIQALNNPVISQFFPTLMLWSFSALLPTIVYYSTLLEAHWTKSAENRIMMHKVYIFLIFMVLILPSLGLTSLDFFFRWLFDRALDLQGPVRLECVFLPDQGAFFVNYVIASAFVGNGMELMRLPGLILYTIRMIMAKSAAERRNIKQNQAFEYEFGAMYAWMLCVFTVVMAYSITCPIIVPFGLIYLLLKHMVDRHNLYYAYLPTKLDKKIHFSAVRQALTAPILCLMWLFFYSLLRMGFT 684          

Query:  107 YNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKL--LNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR---SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNA 2083
            YNS    KN+T      + GIP  + ++V  +  LI +F  +R++ W+YG +A + +                 SEA F     ++S  +    F+ +L     L    +++D+ + + CG DA+ Y  FQR++I ++ V+  LSL +I+P+NL G  L  +   F   TIAN+  ++  LW+H   S+ ++         H  +I +K +     T+ I  +P E   E  +  HFR+AYP+   + VQ+ Y V+ LI L  ++   E++L + Y  L+    R  +I P  CG+ C    CC+ + C   D I +YT     L    T E+S  +  + L + FVTF     A  + +D+      C     KG    SSYS +L    WTVTFA  P+DI W+NL  +G RWWL  + IN  + +V+  L+TP++ ++  +    ++ +  LNNP+++QF P+L++   SA++P IVY+S  L +HWT++ +N  +++K++  L+  VLILPSLGL S+    +WLF   +++  +I+ EC+F+ D GA F NY+I ++FIG+ +ELLRL  L +YT +   +++ A+   + ++  ++++FG  YAW L +F+V+ AYS+  PII PFGL Y+LLKH+VDR+NL    +P+ +   +H  A
Sbjct:   33 YNS---AKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSE---------------AGSEARFQR---LSSSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKE-TVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTY-YTNLQAKTGRRTLINPKPCGQFC----CCEVQGCEREDAISYYTRMNDSLLERITAEESR-VQDQPLGMAFVTFREKSMATYILKDF--NACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLF-DKTSSETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAA 666          

Query:  107 YNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKL--LNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR---SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNA 2083
            YNS    KN+T      + GIP  + ++V  +  LI +F  +R++ W+YG +A + +                 SEA F     ++S  +    F+ +L     L    +++D+ + + CG DA+ Y  FQR++I ++ V+  LSL +I+P+NL G  L  +   F   TIAN+  ++  LW+H   S+ ++         H  +I +K +     T+ I  +P E   E  +  HFR+AYP+   + VQ+ Y V+ LI L  ++   E++L + Y  L+    R  +I P  CG+ C    CC+ + C   D I +YT     L    T E+S  +  + L + FVTF     A  + +D+      C     KG    SSYS +L    WTVTFA  P+DI W+NL  +G RWWL  + IN  + +V+  L+TP++ ++  +    ++ +  LNNP+++QF P+L++   SA++P IVY+S  L +HWT++ +N  +++K++  L+  VLILPSLGL S+    +WLF   +++  +I+ EC+F+ D GA F NY+I ++FIG+ +ELLRL  L +YT +   +++ A+   + ++  ++++FG  YAW L +F+V+ AYS+  PII PFGL Y+LLKH+VDR+NL    +P+ +   +H  A
Sbjct:   33 YNS---AKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSE---------------AGSEARFQR---LSSSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKE-TVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTY-YTNLQAKTGRRTLINPKPCGQFC----CCEVQGCEREDAISYYTRMNDSLLERITAEESR-VQDQPLGMAFVTFREKSMATYILKDF--NACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLF-DKTSSETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAA 666          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFT--VMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFG 2221
            + GIP  + +N++ +  ++ L+ FLRK AW+YG LA L    ++  +   ++S         S ++     E  +  F     N L     M D  L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  G+ L  NS    + TI NV  ES FLW+H      F+ F+  ++    + + F  K+   FT  +MI  VPTE  D  II++HF EAYP     +V   Y+V  LI L  Q+  A    +  Y        +V +  + C R+C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++     R+  DY Y +  C       +SS +  + +  W V  AP PKDI+W++L  R + WW   I IN F+  +   L+TPA+ +N  +    +  +EKL +P+V QF PS+++   +  MPL+VY S  L AHWT+++QN+ +++K +  LV  V+ILPS+GL S+   ++WLF        TI+++C+F+ D GA F NY+ITA+ +GT +EL+RLG L  Y  +   S+S  E   I K+   DFQFG  YAW L +FSVV AYS+  PII PFGL YL +KH+ DRYN+ +   P+ ++  +H  A        +L    +  +  LR G+   +++    + ++ +++ F 
Sbjct:   33 FGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKS------SPSEVSLEAERRDRGFSSWFFNSL----TMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIGTVLDWNSHFGRT-TIVNVSTESKFLWLH--SLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRG-RLYYTAKAKKTGKVMIKTHPCSRLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVQLKRLDLIFVTFQDARTVRRIYDDYKYIH--C--GRHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTIDIYNVTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAAVYQAIFAPLLGLFWMLFFSILRVGSLHSITLFSMSSLIISVVIAFS 700          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFT--VMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFG 2221
            + GIP  + +N++ +  ++ L+ FLRK AW+YG LA L    ++  +   ++S         S ++     E  +  F     N L     M D  L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  G+ L  NS    + TI NV  ES FLW+H      F+ F+  ++    + + F  K+   FT  +MI  VPTE  D  II++HF EAYP     +V   Y+V  LI L  Q+  A    +  Y        +V +  + C R+C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++     R+  DY Y +  C       +SS +  + +  W V  AP PKDI+W++L  R + WW   I IN F+  +   L+TPA+ +N  +    +  +EKL +P+V QF PS+++   +  MPL+VY S  L AHWT+++QN+ +++K +  LV  V+ILPS+GL S+   ++WLF        TI+++C+F+ D GA F NY+ITA+ +GT +EL+RLG L  Y  +   S+S  E   I K+   DFQFG  YAW L +FSVV AYS+  PII PFGL YL +KH+ DRYN+ +   P+ ++  +H  A        +L    +  +  LR G+   +++    + ++ +++ F 
Sbjct:   33 FGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKS------SPSEVSLEAERRDRGFSSWFFNSL----TMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIGTVLDWNSHFGRT-TIVNVSTESKFLWLH--SLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRG-RLYYTAKAKKTGKVMIKTHPCSRLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVQLKRLDLIFVTFQDARTVRRIYDDYKYIH--C--GRHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTIDIYNVTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAAVYQAIFAPLLGLFWMLFFSILRVGSLHSITLFSMSSLIISVVIAFS 700          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFT--VMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFG 2221
            + GIP  + +N++ +  ++ L+ FLRK AW+YG LA L    ++  +   ++S         S ++     E  +  F     N L     M D  L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  G+ L  NS    + TI NV  ES FLW+H      F+ F+  ++    + + F  K+   FT  +MI  VPTE  D  II++HF EAYP     +V   Y+V  LI L  Q+  A    +  Y        +V +  + C R+C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++     R+  DY Y +  C       +SS +  + +  W V  AP PKDI+W++L  R + WW   I IN F+  +   L+TPA+ +N  +    +  +EKL +P+V QF PS+++   +  MPL+VY S  L AHWT+++QN+ +++K +  LV  V+ILPS+GL S+   ++WLF        TI+++C+F+ D GA F NY+ITA+ +GT +EL+RLG L  Y  +   S+S  E   I K+   DFQFG  YAW L +FSVV AYS+  PII PFGL YL +KH+ DRYN+ +   P+ ++  +H  A        +L    +  +  LR G+   +++    + ++ +++ F 
Sbjct:   33 FGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKS------SPSEVSLEAERRDRGFSSWFFNSL----TMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIGTVLDWNSHFGRT-TIVNVSTESKFLWLH--SLFAFLYFLINLAFMGHHCLGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRG-RLYYTAKAKKTGKVMIKTHPCSRLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVQLKRLDLIFVTFQDARTVRRIYDDYKYIH--C--GRHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTIDIYNVTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAAVYQAIFAPLLGLFWMLFFSILRVGSLHSITLFSMSSLIISVVIAFS 700          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLT-FGRTVKR 2236
            + G+P  + INVV + IL+ +F  LRK AW+YG LA L K  ++  +   ++S  E + +  S     +  E  ++ F   L ++      M DE ++ +CG DAV Y  FQR++I ++ V+ +LSLTII+P+NL G+ L  N   F   T+ NVP ++ FLW+H   +L + +      + H + ++++  E+ + T+MI ++P E  D  +I +H  EAYPS     +   + V  L+ L +++  A +   + +      N R+ +  + C ++   C  C  +K   +D  ++Y+    +LT+ F  EK N I+ K+L I FVTF +      + +DY      C +K  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  I++N+ + +++  L+TPA+ +N  +    +  +E L NP++ QF P+L++   S ++P IVY+S     HWT++ +N   M+K F +LV  V+ILPSLGL+S+    +WLF         +K++C+F+ D GA F NY+IT+S IGTA+ELLR+  L +Y+++   ++S+AE   +  S  ++FQFG+ YAWT+ +FSV   YS+  P+I PFGL YL+LKH+VDRYN+ +   P+ ++  +H  A   + V  +L    +  +  LR G    +++  F+  +  +  + FG  +K+
Sbjct:   48 FGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDSLTSLFYGEQSEKEKTPSDSS----PSDSETKDMGFCSWLTSLY----HMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLY-FTTKAQKNGRIMIKTHPCAQI-FCCDICGFEK---VDAEQYYSELEEKLTDEFNAEK-NWISMKRLGIAFVTFRDERMTAVIVKDYSRAR--CRHKPQQ--SSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVAPILCMFWLLFFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCMKK 723          

Query:  125 RKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTF 2218
            +  NT      + G+P  + +N+  + +++ ++ FLRK AW+YG LA L     I + +       E SE   S ++     E  +  F     N     + M DE L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  GS L  +S    + TI NV  ES  LW+H  +S  + +  F   + H      +  ++ + T+MI  VP +  D  +I +HF EAYP     +V   Y+V  LI L  Q+  A     F Y        +V +  + C R+C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++   A RVR+DY Y    C  +  +  SS +  + S  W VT AP PKDI+W++L  R + WW   I IN F+  +   L+TPA+ +N  +    +  +EKL NP+V QF PS+++   + ++PLIVY+S  L AHWT+++QN+ +++K +  LV  V+ILPS+GL S+   ++WLF        +I+++C+F+ D GA F NY+ITA+ +GT +ELLRLG LF Y+ +   SRS  E   I K+   DFQFG  YAW + +FSVV AYS+  PII PFGL YL +KHL DRYN+ +   P+ ++  +H  A        +L    +  +  LR G+   ++I      ++ +++ F
Sbjct:   24 QSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALL-----IHNDSLTSLIYGEQSEKT-SPSETSLEMERRDKGFCSWFFNS----ITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFART-TIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLF-YTAKAKKTGKVMIRIHPCARLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQ--CGVQPQQ--SSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAF 701          

Query:  101 DRYNS---YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELE-HDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR---SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQS 2311
            DR N    Y   KN+T      + GIP  + I+V  +  LI +F  +R++ W+YG +A + +                 SE  F      +S    +   +      L    +++D+ + + CG DA+ Y  FQR++I ++ V+  LSL +I+P+NL G  L  +   F   TIAN+  ++  LW+H   ++ ++         H  +I +K +     T+ I  +P +   E  +  HFR+AYP+   + VQ+ Y V+ LI L  ++   E++L + Y  L+     R  + P  CG+ C    CC+ + C   D I +YT    RL    T E+ + +  + L + FVTF+    A  + +D+      C +   KG    SS+S +L +  WTVTFA  P+DI W+NL  +G RWWL  + IN  + + +  L+TP++ L+  +    ++ +  LNNP+++QF P+L++   SA++P IVY+S  L +HWTK+ +N  +M K++  L+  VLILPSLGL S+    +WLF   +++  +I+ EC+F+ D GA F NY+I ++FIG  +ELLRL  L +YT +   +++ A+   + ++  + ++FG  YAW L +F+V+ AYS+  PII PFGL Y+LLKH+VDR+NL  + +P+ +   +H  A        +L    +  +  LR G     ++  FL  +L +L+    T   +   +S + Y       D+  + ++
Sbjct:   25 DRPNDSYCYNSAKNSTVLQGVTFGGIPTVLLIDVSCFLFLILVFSIIRRRFWDYGRIALVSE---------------ADSEPRFQRLSSTSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVVSFLSLCVILPVNLSGDLLDKDPYSFGRTTIANLQTDNDLLWLHTIFAVIYLFLTVGFMRHHTQSIKYKEENLVRRTLFITGLPRDARKE-TVESHFRDAYPTCEVVDVQLCYNVAKLIYLCKERKKTEKSLTY-YTNLQVKTGQRTLINPKPCGQFC----CCEVQGCEWEDAISYYTRMKDRLLERITEEERH-VQDQPLGMAFVTFQEKSMATYILKDF--NACKCQSLQCKGEPQPSSHSRELYTSKWTVTFAADPEDICWKNLSIQGLRWWLQWLGINFTLFLGLFFLTTPSIILSTMDKFNVTKPIHALNNPIISQFFPTLLLWSFSALLPSIVYYSTLLESHWTKSGENQIMMTKVYIFLIFMVLILPSLGLTSLDFFFRWLF-DKTSSEASIRLECVFLPDQGAFFVNYVIASAFIGNGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFQYEFGAMYAWMLCVFTVIMAYSITCPIIAPFGLIYILLKHMVDRHNLYFIYLPAKLEKGIHFAAVNQALAAPILCLFWLYFFSFLRLGMKAPATLFTFLVVLLTILVCLAHTCFGYFKHLSPLNYKTEEPASDKGSEAEA 743          

Query:  107 YNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKL--LNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR---SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNA 2083
            YNS    KN+T      + GIP  + ++V  +  LI +F  +R++ W+YG +A + +                 SEA F     ++S  +    F+ +L     L    +++D+ + + CG DA+ Y  FQR++I ++ V+  LSL +I+P+NL G  L  +   F   TIAN+  ++  LW+H   S+ ++         H  +I +K +     T+ I  +P E   E  +  HFR+AYP+   + VQ+ Y V+ LI L  ++   E++L + Y  L+    R  +I P  CG+ C    CC+ + C   D I +YT     L    T E+S  +  + L + FVTF     A  + +D+      C     KG    SSYS +L    WTVTFA  P+DI W+NL  +G RWWL  + IN  + +V+  L+TP++ ++  +    ++ +  LNNP+++QF P+L++   SA++P IVY+S  L +HWT++ +N  +++K++  L+  VLILPSLGL S+    +WLF   +++  +I+ EC+F+ D GA F NY+I ++FIG+ +ELLRL  L +YT +   +++ A+   + ++  ++++FG  YAW L +F+V+ AYS+  PII PFGL Y+LLKH+VDR+NL    +P+ +   +H  A
Sbjct:   33 YNS---AKNSTVLQGVTFGGIPTVLLLDVSCFLFLILVFSIIRRRFWDYGRIALVSE---------------AGSEARFQR---LSSSSSGQQDFENELGCCPWLTAIFRLHDDQILEWCGEDAIHYLSFQRHIIFLLVVISFLSLCVILPVNLSGDLLGKDPYSFGRTTIANLQTDNDLLWLHTVFSVIYLFLTVGFMWHHTRSIRYKEESLVRQTLFITGLPREARKE-TVESHFRDAYPTCEVVDVQLCYSVAKLIYLCKERKKTEKSLTY-YTNLQAKTGRRTLINPKPCGQFC----CCEVQGCEREDAISYYTRMNDSLLERITAEESR-VQDQPLGMAFVTFREKSMATYILKDF--NACKCQGLRCKGEPQPSSYSRELCVSKWTVTFASYPEDICWKNLSIQGVRWWLQWLGINFSLFVVLFFLTTPSIIMSTMDKFNVTKPIHALNNPVISQFFPTLLLWSFSALLPSIVYYSTLLESHWTRSGENRIMVSKVYIFLIFMVLILPSLGLTSLDFFFRWLF-DKTSSETSIRLECVFLPDQGAFFVNYVIASAFIGSGMELLRLPGLILYTFRMIMAKTAADRRNVKQNQAFEYEFGAMYAWMLCVFTVIMAYSITCPIIVPFGLIYILLKHMVDRHNLYFAYLPAKLEKRIHFAA 666          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFT--VMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNA 2083
            + GIP  + +N++ +  ++ ++ FLRK AW+YG LA L    ++  +   ++S       ++ +       E  +  F     N L     M D  L  +CG DA IY  FQ +LI  V ++ + SL II+P+N  GS L  +S    + TI NV  ES FLW+H   +  + L  F     H   + F  K+   FT  +MI  VPTE  D   I++HF EAYP     +V   Y+V  LI L  Q+  A    +  Y        +V +  + C  +C  CKC    K   +D  ++Y+    +LT+ F  E  N +  K+L + FVTF++     R+  DY Y N  C    M+  SS +  + ++ W V  AP PKDI+W++L  R + WW   I IN  +  +   L+TPA+ +N  +    +  +EKL +P+V QF PS+++   + +MPL+VY+S  L AHWT++ QN+ +M K +  LV  V+ILPS+GL S+   ++WLF        TI+++C+F+ D GA F NY+IT++  GT +EL+RLG L  Y  +   SRS  E   I K++  DFQFG  YAW L +FSVV AYS+  PII PFGL YL +KH+ DRYN+ +   P+ ++  +H  A
Sbjct:   33 FGGIPTVLLLNIILWVCVVLVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKSSPSEVYLEA------ERRDKGFSTWFFNSL----TMRDRDLINKCGEDARIYIMFQYHLIIFVLILCIPSLGIILPVNYIGSALDWSSHFGRT-TIVNVSTESQFLWLHSIFAFMYFLTNFAFMGHHC--LGFVPKKNLHFTRTLMITYVPTEIQDPETISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMRG-RLYYTAKAKKTGKVMIKVHPCSHLCF-CKCWTCFK--EVDAEQYYSELEEQLTDEFNAEL-NRVQLKRLDLIFVTFQDARTVKRIHNDYKYIN--CGRHPMQ--SSVTTIVKNNHWRVARAPHPKDIIWKHLSIRRFSWWARFIAINTSLFFLFFFLTTPAIIINTIDMYNVTRPIEKLQSPVVTQFFPSVLLWAFTVIMPLLVYFSAFLEAHWTRSNQNLIIMYKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITSALFGTGMELMRLGSLCTYCTRLFLSRSEPERVHIRKNLAMDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLNAQIHMAA 654          

Query:  110 NSYIPRKNNTFTI-STAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAP-------------RKESRSEHSEA--IFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDF-KAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFS---ERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDL---------DLFTLEKIKTARSSVTSINDD----NDTIPLHNR 2503
            N Y P+ ++   I    YEGIPQN+ INV+A+  LI LF  LRK AWNYG +A L +    E  AP             R+E R   SE        DP +  ++   ++      IL +F ++ D+ ++ +CG DAV Y  FQR++I ++S+ MV+SL I +P+N++G           + T++N+  +S +LWIH  +S+ F+    FI       +D  +     S T+MIN++P   C++  + +HF EAYP    I +Q  Y++S LI L   +  A  A  +   E    N R+ V P LCG VC+ C  C  K  + ID  E+YT E  +L +L   EK  AI  + + I FVTF +  QA +VR+D+   N+ C   S  G SS S       W+V FAP P +I W NL      W+L   +IN F+ IV+  L+TPAV +N  +  +FS     +EK++ P+++QF P+L++   SA+MP++V +SD+  +HWTK+T N  +M K F  L+  V+ILPSLGL S     +W   +N T     +WEC+F+ D GA F NY+IT+SFIGTALEL+R  ELFMY  K SC++SRAE   + +++LW+F FGV YAWTL  FS+++ YSV  P+ITPFG  Y+LLKH VDRYN+     PS ++ ++HT A   + +  ++ Q T+  +  LR G   + +I   + F   L L   +   RW   ++ + Y K S+    +     + VD    V+  G       +  VF+P  +T             + T   + + R +  SIN +       IP  +R
Sbjct:   37 NYYRPKNSSHLVIIPGGYEGIPQNLTINVIAWICLIILFSVLRKNAWNYGRMALLQRRERRE-TAPGYSEYNIWTQIFYRREDRDGDSEGHKAAPSFDPGSHYDHGMFSW------ILAVF-RIKDDQIRSKCGDDAVQYLSFQRHIIVMMSITMVVSLAIALPINMQGDLKGDEKQFGHT-TLSNLDPKSWYLWIHVGLSILFVPIAIFIMRHFSKRLDIPEVDSTVSRTLMINHIPRSSCNKADLLKHFNEAYPEYEVIDIQFAYDLSKLIKLDRARQFALHARNYSVSEAMSGN-RMLVRPFLCGNVCVCCDPCCPK--SKIDAAEYYTSEERQLASLVDQEKLKAIK-RPVGIAFVTFASNLQAAKVRQDHR-PNWRC--GSNPGSSSLSVMFKPHRWSVDFAPRPDEINWGNLAIPSRFWYLRSFLINSFLFIVLFFLTTPAVVVNTLDIFQFSTITSTIEKMS-PVLSQFLPTLLLWTTSALMPVMVAYSDEWMSHWTKSTANHTIMRKTFIFLMFMVVILPSLGLTSAQAFFEWATRSNGT----YRWECVFLPDNGAFFVNYVITSSFIGTALELMRFSELFMYACKLSCAKSRAEVPGVRRNLLWEFNFGVQYAWTLLNFSLITMYSVSCPLITPFGFVYVLLKHFVDRYNIFFAYAPSRINKNIHTTAINFVMIAFLILQLTLFFFSLLRYGLFGV-TIFALVGFCATLFLVVVQASFRWFRGLAPISYRKFSEPRGNRNSPGRQRVDSFSTVNSQGH------QNNVFLPEVLTESQCNGPAHLMETIATTSVLDSGRPNKNSINGEMVTVEQPIPCRDR 839          

Query:   80 MSITLQCDRYNSYIPRKNNT--FTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKES--RSEHSEAIFSDTDPIASKENINLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLG--LLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVTSINDDNDTIPLHNRNYGAT 2518
            ++  L CDRY S+    N T   TI   YEGIP+N+ IN + + +L+ LF  LRKKAW+YG +A + +       A R  S    +H E   S    + S E+++           + LP F K+ D  +  +CG DAV Y  FQR L+  ++++ VLS+ +I+P+N +G           + TI+N+  +S  LW+H   S+ F+    +      +++ F+  +E + T+MI+++P + C +  + QHF+EAYP      +Q  Y +S LI+    +  A EA  F   EL+    R  ++P  CGRVC  C  C  ++   +D IEFY+     LTN    EK+ +   K L I FVTFEN   A RV  D+      C        SS    L  +DW V++AP P +I W+NL    W WW+  IVIN  + I++  LSTP++ +   +N+ F + LE L++P++ QF P+L++   SA++P +VY+SDQ   HWT+T ++  VM K+F  L++ VL+LPSLGL S+    ++   T S     I+WECIF+ D GA F NY+IT++ IGT LEL+R  EL ++ +K  C+RS AE  ++ +SVLW+FQFG  YAW L +F+V   YS+  P+I PFGL YL+LK+ VDRYN+     PS ++ ++HT+A   + + +VL Q  +  +  +R  T  I  I  F A  L   +L+  GR       S  W K              Q  PV       E G   I    ++ F+P  +  D         K   SS  ++N ++     HN N  A 
Sbjct:   12 VAANLTCDRYYSWDEFHNKTKLITIYGGYEGIPENLLINFIVWLLLLILFAILRKKAWDYGRIALVSRR------AERWTSLFYGDHDEK--SVNAALGSVESLDKHIDHHDTGFCSWLPAFFKIKDSHILHKCGPDAVQYLSFQRYLLVYLALICVLSVAVILPVNFQGDQEQDQQQFGHT-TISNLKLDSTTLWVHAVFSVVFIGLAVYFMRHFSSSLSFEEDDEATRTLMISHIPLDKCFKNTLQQHFQEAYPEFTVQDIQFAYNISDLINKDNSRKKAHEARVFSENELKTTGQRPTMVPYKCGRVCCCCHSCGCEE---VDAIEFYSRRERELTNQVEVEKATSFQ-KALGIAFVTFENEYMAQRVCVDFRTS---CKGSHNPHPSSLGRDLALEDWNVSYAPGPDNIYWENLSLDPWVWWIKCIVINGVLIILLFFLSTPSILMAALDNINFKKALEDLHSPILVQFLPTLILWSFSALLPWLVYYSDQFVGHWTRTAEHHTVMRKIFIFLILMVLVLPSLGLTSIKAFFEY---TVSNQTKEIRWECIFLPDNGAFFVNYVITSALIGTGLELMRFPELSLFVIKLLCARSHAEQASVRRSVLWEFQFGQNYAWMLTIFAVTMTYSIPCPLIVPFGLLYLVLKYAVDRYNIYFAYAPSKINKNIHTSAINFVLIAVVLLQCNILFFTVIR--TDPIQGISGFSAITLFIIMLMFIGR------LSFGWFK--------------QFTPVYYRTLDGESGTGRISTTSDQPFIPSVLRDDR--------KQPPSSPDALNPNS-----HNDNQAAA 779          

Query:   80 MSITLQCDRYNSYIPRKNNT--FTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEH-------SEAIFSDTD------PIASKENINLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLG--LLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSD 2410
            ++  L CDRY S+    N T   TI   YEGIP+N+ IN + + +L+ LF  LRKKAW+YG +A + +         R E RS +       +   + D D       + S E+++           + LP F K+ D  +  +CG DAV Y  FQR L+  ++++ VLS+ +I+P+N +G           + TI+N+  +S  LW+H   S+ F+    +      +++ F+  +E + T+MI+++P + C +  + QHF+EAYP      +Q  Y +S LI+    +  A EA  F   EL+    R  ++P  CGRVC  C  C  ++   +D IEFY+     LTN    EK+ +   K L I FVTFEN   A RV  D+      C        SS    L  +DW V++AP P +I W+NL    W WW+  IVIN  + I++  LSTP++ +   +N+ F + LE L++P++ QF P+L++   SA++P +VY+SDQ   HWT+T ++  VM K+F  L++ VL+LPSLGL S+    ++   T S     I+WECIF+ D GA F NY+IT++ IGT LEL+R  EL ++ +K  C+RS AE  ++ +SVLW+FQFG  YAW L +F+V   YS+  P+I PFGL YL+LK+ VDRYN+     PS ++ ++HT+A   + + +VL Q  +  +  +R  T  I  I  F A  L   +L+  GR       S  W K              Q  PV       E G   I    ++ F+P  +  D
Sbjct:   12 VAANLTCDRYYSWDEFHNKTKLITIYGGYEGIPENLLINFIVWLLLLILFAILRKKAWDYGRIALVSR---------RAERRSLNDSRYNVWTSLFYGDHDEKSVNAALGSVESLDKHIDHHDTGFCSWLPAFFKIKDSHILHKCGPDAVQYLSFQRYLLVYLALICVLSVAVILPVNFQGDQEQDQQQFGHT-TISNLKLDSTTLWVHAVFSVVFIGLAVYFMRHFSSSLSFEEDDEATRTLMISHIPLDKCFKNTLQQHFQEAYPEFTVQDIQFAYNISDLINKDNSRKKAHEARVFSENELKTTGQRPTMVPYKCGRVCCCCHSCGCEE---VDAIEFYSRRERELTNQVEVEKATSFQ-KALGIAFVTFENEYMAQRVCVDFRTS---CKGSHNPHPSSLGRDLALEDWNVSYAPGPDNIYWENLSLDPWVWWIKCIVINGVLIILLFFLSTPSILMAALDNINFKKALEDLHSPILVQFLPTLILWSFSALLPWLVYYSDQFVGHWTRTAEHHTVMRKIFIFLILMVLVLPSLGLTSIKAFFEY---TVSNQTKEIRWECIFLPDNGAFFVNYVITSALIGTGLELMRFPELSLFVIKLLCARSHAEQASVRRSVLWEFQFGQNYAWMLTIFAVTMTYSIPCPLIVPFGLLYLVLKYAVDRYNIYFAYAPSKINKNIHTSAINFVLIAVVLLQCNILFFTVIR--TDPIQGISGFSAITLFIIMLMFIGR------LSFGWFK--------------QFTPVYYRTLDGESGTGRISTTSDQPFIPSVLRDD 766          

Query:  110 NSYIPRKNNTFTI-STAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGK-PLNIEHVAPRKESRSEHSEA--IFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDF-KAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFS---ERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQ 2308
            N Y P+ ++   I    YEGIPQN+ INV+A+  LI LF  LRK AWNYG +A L +       +  R+E R   SE        DP +  ++   ++      IL +F ++ D+ ++ +CG DAV Y  FQR++I ++S+ MV+SL I +P+N++G           + T++N+  +S +LWIH  +S+ F+    FI       +D  +     S T+MIN++P   C++  + +HF EAYP    I +Q  Y++S LI L   +  A  A  +   E    N R+ V P LCG VC+ C  C  K  + ID  E+YT E  +L +L   EK  AI  + + I FVTF +  QA +VR+D+   N+ C   S  G SS S       W+V FAP P +I W NL      W+L   +IN F+ IV+  L+TPAV +N  +  +FS     +EK++ P+++QF P+L++   SA+MP++V +SD+  +HWTK+T N  +M K F  L+  V+ILPSLGL S     +W   +N T     +WEC+F+ D GA F NY+IT+SFIGTALEL+R  ELFMY  K SC++SRAE   + +++LW+F FGV YAWTL  FS+++ YSV  P+ITPFG  Y+LLKH VDRYN+     PS ++ ++HT A   + +  ++ Q T+  +  LR G   + +I   + F   L L   +   RW   ++ + Y  S +    + DL 
Sbjct:   37 NYYRPKNSSHLVIIPGGYEGIPQNLTINVIAWICLIILFSVLRKNAWNYGRMALLQRRERRWTQIFYRREDRDGDSEGHKAAPSFDPGSHYDHGMFSW------ILAVF-RIKDDQIRSKCGDDAVQYLSFQRHIIVMMSITMVVSLAIALPINMQGDLKGDEKQFGHT-TLSNLDPKSWYLWIHVGLSILFVPIAIFIMRHFSKRLDIPEVDSTVSRTLMINHIPRSSCNKADLLKHFNEAYPEYEVIDIQFAYDLSKLIKLDRARQFALHARNYSVSEAMSGN-RMLVRPFLCGNVCVCCDPCCPK--SKIDAAEYYTSEERQLASLVDQEKLKAIK-RPVGIAFVTFASNLQAAKVRQDHR-PNWRC--GSNPGSSSLSVMFKPHRWSVDFAPRPDEINWGNLAIPSRFWYLRSFLINSFLFIVLFFLTTPAVVVNTLDIFQFSTITSTIEKMS-PVLSQFLPTLLLWTTSALMPVMVAYSDEWMSHWTKSTANHTIMRKTFIFLMFMVVILPSLGLTSAQAFFEWATRSNGT----YRWECVFLPDNGAFFVNYVITSSFIGTALELMRFSELFMYACKLSCAKSRAEVPGVRRNLLWEFNFGVQYAWTLLNFSLITMYSVSCPLITPFGFVYVLLKHFVDRYNIFFAYAPSRINKNIHTTAINFVMIAFLILQLTLFFFSLLRYGLFGV-TIFALVGFCATLFLVVVQASFRWFRGLAPISYRVSQRRDTDETDLH 756          

Query:  110 NSYIPRKNNTFTI-STAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAP-------------RKESRSEHSEA--IFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEP-SFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFS---ERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQ 2308
            N Y P+ ++   I    YEGIPQN+ INV+A+  LI LF  LRK AWNYG +A L +    E  AP             R+E R   SE        DP +  ++   ++      IL +F ++ D+ ++ +CG DAV Y  FQR++I ++S+ MV+SL I +P+N++G           + T++N+  +S +LWIH  +S+ F+    FI       +D    +   S T+MIN++P   C++  + +HF EAYP    I +Q  Y++S LI L   +  A  A  +   E    N R+ V P LCG VC+ C  C  K  + ID  E+YT E  +L +L   EK  AI  + + I FVTF +  QA +VR+D+   N+ C   S  G SS S       W+V FAP P +I W NL      W+L   +IN F+ IV+  L+TPAV +N  +  +FS     +EK++ P+++QF P+L++   SA+MP++V +SD+  +HWTK+T N  +M K F  L+  V+ILPSLGL S     +W   +N T     +WEC+F+ D GA F NY+IT+SFIGTALEL+R  ELFMY  K SC++SRAE   + +++LW+F FGV YAWTL  FS+++ YSV  P+ITPFG  Y+LLKH VDRYN+     PS ++ ++HT A   + +  ++ Q T+  +  LR G   + +I   + F   L L   +   RW   ++ + Y  S +    + DL 
Sbjct:   37 NYYRPKNSSHLVIIPGGYEGIPQNLTINVIAWICLIILFSVLRKNAWNYGRMALLQRRERRE-TAPGYSEYNIWTQIFYRREDRDGDSEGHKAAPSFDPGSHYDHGMFSW------ILAVF-RIKDDQIRSKCGDDAVQYLSFQRHIIVMMSITMVVSLAIALPINMQGDLKGDEKQFGHT-TLSNLDPKSWYLWIHVGLSILFVPIAIFIMRHFSKRLDIPEVDSTVSRTLMINHIPRSSCNKADLLKHFNEAYPEYEVIDIQFAYDLSKLIKLDRARQFALHARNYSVSEAMSGN-RMLVRPFLCGNVCVCCDPCCPK--SKIDAAEYYTSEERQLASLVDQEKLKAIK-RPVGIAFVTFASNLQAAKVRQDHR-PNWRC--GSNPGSSSLSVMFKPHRWSVDFAPRPDEINWGNLAIPSRFWYLRSFLINSFLFIVLFFLTTPAVVVNTLDIFQFSTITSTIEKMS-PVLSQFLPTLLLWTTSALMPVMVAYSDEWMSHWTKSTANHTIMRKTFIFLMFMVVILPSLGLTSAQAFFEWATRSNGT----YRWECVFLPDNGAFFVNYVITSSFIGTALELMRFSELFMYACKLSCAKSRAEVPGVRRNLLWEFNFGVQYAWTLLNFSLITMYSVSCPLITPFGFVYVLLKHFVDRYNIFFAYAPSRINKNIHTTAINFVMIAFLILQLTLFFFSLLRYGLFGV-TIFALVGFCATLFLVVVQASFRWFRGLAPISYRVSQRRDTDETDLH 767          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENI-----NLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFL 2188
            +  R  +T      + G+P  + ++ + +  L+ +F  LRK AW+YG LA +      +    R + R   + A+ +  D  A  E +     ++ F ++     + L    ++ D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ II+P+N  G  L +N+  F   TIAN+   +  LW+H T +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   ++ ++ ++V+ L+ L +++   E + +F Y +L    H   +I P  CG +C    CC  K C   D + +YT+   +L   +  E+   +N K L + FVTF+N      + +D+   Q + C  +     S +S  L + +WTV++AP P+++ W++L   G  WWL  ++IN F+ I++  L+TPA+ ++  +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF         +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R G     S+  F+
Sbjct:   34 FAARIRSTVLQGLPFGGVPTVLALDFMCFLGLLFVFSILRKVAWDYGRLALVSDADRQDQRYRRLDEREYVASAMQTPVD--ARYERLTSVCSSVDFDQRDSGFCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGI-NKYAEESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKF-YTDLMAKEHVSTMINPKPCGHLC----CCIIKGCEQEDAVNYYTNLEAKLREEYKKEREK-VNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLFWLLFFSTVRTGFDTATSMFTFV 725          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRK-ESRSEHSEAIFSDTDPIASKENINLTFKEK---LLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRG 2155
            +  R  +T      + G+P  + ++ + +  L+ +F  LRK AW+YG LA +    ++        ++R E   ++ S  D           F ++     + L    ++ D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ II+P+N  G  L +N+  F   TIAN+   +  LW+H T +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   ++ ++ ++V+ L+ L +++   E + +F Y +L    H   +I P  CG +C    CC  K C   D + +YT+   +L   +  E+   +N K L + FVTF+N      + +D+   Q + C  +     S +S  L + +WTV++AP P+++ W++L   G  WWL  ++IN F+ I++  L+TPA+ ++  +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF         +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R G
Sbjct:   34 FAARIRSTVLQGLPFGGVPTVLALDFMCFLGLLFVFSILRKVAWDYGRLALVSDADSVASAMQTPVDARYERLTSVCSSVD-----------FDQRDSGFCSWLTAIFRIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGI-NKYAEESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKF-YTDLMAKEHVSTMINPKPCGHLC----CCIIKGCEQEDAVNYYTNLEAKLREEYKKEREK-VNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLFWLLFFSTVRTG 701          

Query:  116 YIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRG 2155
            +  R  +T      + G+P  + ++ + +  L+ +F  LRK AW+YG LA                        + SD D                           D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ II+P+N  G  L +N+  F   TIAN+   +  LW+H T +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   ++ ++ ++V+ L+ L +++   E + +F Y +L    H   +I P  CG +C    CC  K C   D + +YT+   +L   +  E+   +N K L + FVTF+N      + +D+   Q + C  +     S +S  L + +WTV++AP P+++ W++L   G  WWL  ++IN F+ I++  L+TPA+ ++  +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF         +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R G
Sbjct:   34 FAARIRSTVLQGLPFGGVPTVLALDFMCFLGLLFVFSILRKVAWDYGRLA------------------------LVSDAD--------------------------RDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGI-NKYAEESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKF-YTDLMAKEHVSTMINPKPCGHLC----CCIIKGCEQEDAVNYYTNLEAKLREEYKKEREK-VNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLFWLLFFSTVRTG 658          

Query:  428 KMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVI-PNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFL 2188
            ++ D+ ++++CG DAV Y  FQR++I ++ V+ VLS+ II+P+N  G  L +N+  F   TIAN+   +  LW+H T +  ++L   +   +H + + +K  +    T+ I+ +  ++ +E  I QHF +AY +   ++ ++ ++V+ L+ L +++   E + +F Y +L    H   +I P  CG +C    CC  K C   D + +YT+   +L   +  E+   +N K L + FVTF+N      + +D+   Q + C  +     S +S  L + +WTV++AP P+++ W++L   G  WWL  ++IN F+ I++  L+TPA+ ++  +    ++ +E LNNP++ QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL+S+    +WLF         +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS AE   + K   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHLVDRYN+ +  +PS +   +H+ A   +    +L    +  +  +R G     S+  F+
Sbjct:   63 RIKDDEIREKCGEDAVHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGDLLDNNAYSFGRTTIANLKAGTNLLWLHTTFAFLYLLLTVYSMRRHTSKMHYKEDDLVKRTLFIHGI-NKYAEESQIKQHFEQAYENCVVLEARICFDVAKLMYLESERRKTERSKKF-YTDLMAKEHVSTMINPKPCGHLC----CCIIKGCEQEDAVNYYTNLEAKLREEYKKEREK-VNTKPLDMAFVTFQNEAMTALILKDFNACQCHGCHCRREPKSSPFSSILQTYNWTVSYAPDPQNVYWEHLSVGGLTWWLRCLIINCFLFILLFFLTTPAIIISTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKTFLDQAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLLLARSAAERRNVKKHQAYEFQFGAAYAWLMNVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLFWLLFFSTVRTGFDTATSMFTFV 644          

Query: 1031 IDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYL-CFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLN----NPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAI 1873
            ++ +E Y      L+     E+S  +  + L + FVTF++      +  DY   N L C+ +    R   S +L +  W V +AP P  I+W+NL  +G  WW  + V+N  + +++  L+TPA+ +N  +    ++ +E LN    +P+V QF P+L++   SAV+P +VY+S  L +HWT++T+N   M+K +  L+  VLILPSLGL S+    +WLF  +     ++++EC+F+ D GA F NY+IT++FIGTA+ELLR+  L +Y ++   +RS+AE   +
Sbjct:   42 VNAVEHYRGLKNSLSAECEKERSK-VRSQPLGMAFVTFQDDRMTSDILADY---NLLRCWRRPHVSR--LSEELGASSWRVRYAPDPNSIIWENLQVQGLMWWCRVFVLNALLFLLLFFLTTPAIIVNTMDKFNVTKPIESLNRGPQSPIVTQFLPTLLLWAFSAVLPFLVYYSVFLESHWTRSTENRTTMHKCYFYLIFMVLILPSLGLTSLNVFFRWLFDKDFLEQGSVRFECVFLPDNGAFFVNYVITSAFIGTAMELLRVPGLLLYALRLCWARSKAERKNV 321          

Query:  728 AKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALR------------------VRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVM 1588
            A+ + S T+ I  +P     E I+  HF EAYPS     VQ  Y V  LI L  ++  A +A  + Y+ +  +  R K+   LC        CC       ++ +EFYT    RLT+    EK   I    L + FVTF +   A +                  +    +++  L   K+    SS+   L S  W V +AP P  I+W+NL  +G+ WW+ +IV+N F+ I++   STP++ +N  +    ++ +E LN+P++ QF P+L++   S+++PL+VY+S  L AHWT++++N A M
Sbjct:    7 ARGQVSRTLFIIGIPKHLDKEDILKSHFYEAYPSCTITDVQFCYNVEKLIKLDKERKKAAKARAY-YDNMTDETMRPKMYGELC--------CCDCYGYRKVNALEFYTALESRLTDECEEEK-RKIPDNPLGMAFVTFHDDKSATQNLTTESLAIVVGCAKLPALEVPGIWRGCLGSPKT----SSFGDMLRSKHWGVKYAPDPNSIIWENLTVQGFSWWVKVIVLNTFLFILLFFFSTPSIVVNTIDKFNVTKPVESLNSPIITQFLPTLLLWTFSSLLPLLVYYSVFLEAHWTRSSENRATM 297          

Query: 1709 KWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTY 1996
            +  C+F+ D GA F NY++TA+ +G+A  LLRL EL +Y ++   +RS A  + + K   ++F +G+ YAWT+ + +V  +YSV  PIITPF L Y
Sbjct:    1 RHRCVFLPDNGAFFVNYVVTAALLGSAARLLRLPELALYGLRLCLARSDAHRHHVRKRCCYEFPYGLEYAWTMCIITVTMSYSVTCPIITPFVLLY 96          

Query:  218 LFLFLRKKAWNYGNLA--------WLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKG--RSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFS--ERLEKLN---NPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNL-IHVNVPS--IVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEI-KERVFVPPQMTSDLDLFTLEKIKTARSSVTSINDDNDTIPLHNRN-YGATVPNI 2530
            LF  +R+  W+YG LA        W      +      K+ + +     F +               + LL+ +P+ +++ DE +  +CG DA+ Y +FQ++LI    ++  LS+ I++P+N  G+     +S  ++ T++N+  +S   W+H   +L +++ +  I     +  + ++  E + TVMI N+P     E+I  QHF E Y      +VQ+ Y    L S+  +  AA    + C E L+ +  R +   +   +V     CC  K    +DGIE++T    +    F   K +    K L + FVTF N + + +  +D        FN    G   SS S ++ SD W V  AP+  DILW++L      WW   ++IN+ + I ++ ++TP V +  +N +K S  E+  KL    NP   QF P++++   SA++P++V +S    AHWT++    +VM K +  L++ V++LPSL L S   L +     + +A    +  C+F+ + GA F NY++T++ IGTALEL R  EL  Y V+   ++   E   + +  + +F FG  YAW + +FSV+  YS+  P++TPFGL YL  KH+VDRYNL  +   P+   V  SVH+ A     +       ++  +  +R G  D  +I   +   L L    GR                +  F  R G  + +  + E+D        I E+     ++PP + S  +           S+  S  +D+    L  R  YG T P +
Sbjct:    3 LFCVIRRLVWDYGRLAVTQKEDLGWTSVFYGLNVNGNGKDKQEDKPSVTFPEVK------------DKGLLSWVPVLLRVTDEHIHVKCGMDALQYIQFQKHLIVYSVIIFCLSIGIVLPINYSGTNEYERNSFGAT-TVSNLEAQSSMFWLHAVFALLYIIIIVVILRHFTSLFNMESLHESATTVMITNIPKNVTKELI-QQHFVEVYDDSMIEEVQLAYNCDKLQSIERKLEAARLGREHCQELLQLNGERPQTTVS-TSKVSPCMMCCGVKH---VDGIEYFTEVEGKARVEFEQTKQS---LKSLGVAFVTFVNEETSQKCLKD--------FNTIKHGSPESSVSRKIFSDHWNVASAPLTGDILWEHLSVDPESWWARALIINIILFIFVLFITTPTVLITSFNEIKASIVEKNPKLRVAPNPFFTQFLPTIMLWTFSAILPVVVSYSSYFEAHWTRSRLEHSVMIKTYVFLLLMVIVLPSLALTSADALFQ--VTLSGSALLKSRLACVFLPNNGAFFVNYLVTSALIGTALELCRFPELAAYAVRMCFAKDEGEKRLVRRESVREFAFGHQYAWMIVIFSVMVVYSIACPLVTPFGLLYLTFKHVVDRYNLYFNYRSPAYKYVDPSVHSTAVVFTIISSFFLLLSILFFGVVRLGINDPQTIFTIVLVALTLAAFVGRV---------------AFGFFKRLGPFKQRLNNDEED-------HITEVYMPEAYLPPVLRSKRE-----------SAAASAGEDSSPPQLTRRKTYGTTSPTV 729          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSI 2176
            + G+P  + INVV +  L+ +F  LRK AW+YG LA L +  ++  +   + S  E +    S+T P +  +  ++ F   LL++      M D  ++ +CG DAV Y  FQR++I +++V+ +LSL +I+P+N  G+ L  +   F   T+ANV  +  FLW+H   +L + +      + H   ++++  E+ + T+MI ++P E CD  +I +HF EAYPS      +  ++V  LI L  ++  A +   +   + + +  ++ +  +LC  +   C  C  ++   +D  ++Y+    + T+ F  EKS  I+ K+L I FVTF +      + +DY      C  +  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  +++N+ + +++  L+TPA+ +N  +    +  +E L +P++ QF P+L++   S ++P IVY+S    +HWT++ QN   M+K F +LV  V+ILPSLGL+S+     WLF  N      +K++C+F+ D GA F NY+IT+S IGT++ELLR+  L +Y  +   ++S+AE   + KS  ++FQFG+ YAWT+ +F+V   YS+  PIITPFGL Y +LKH+VDRYN+ +  +P+ ++  +H  A   + V  +L    +  +  LR G    ++I
Sbjct:   55 FGGVPTVLAINVVLWMFLLLIFSCLRKAAWDYGRLALLMENDSLTSLFYGEPSEKEKTP---SETSP-SDSDTKDMGFCSWLLSL----YYMKDGEIRSKCGIDAVTYLSFQRHIILLMTVVSLLSLAVILPVNFSGNLLGDSPQNFGRTTLANVSAKDNFLWLHSIFALVYFIITMLCMAHHAIRLEYREDEKVARTLMITSIPREICDPGLITKHFHEAYPSCTVTDNRFCFDVHKLIKLDLERRKAMKGRLYFTTKAQKEG-KIMIKTHLCAHI-FGCDICGFER---VDAEQYYSELEEKRTDEFNAEKSR-ISLKRLGIAFVTFRDERMTAVIVKDY--SRVRCRRRPQQ--SSITTVVQSHKWGVSYAPAPSDIIWENLSVCGSRWWLRCVLLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRSPVITQFLPTLLLWAFSVLLPFIVYYSAFFESHWTRSGQNQVTMHKCFLLLVFMVIILPSLGLSSLDLFFTWLFDVNFLEEKEVKFQCVFLPDNGAFFVNYVITSSLIGTSMELLRIPALTVYAFRLCFAKSQAERIHVKKSQAYEFQFGLEYAWTMCIFAVSMTYSITCPIITPFGLLYAILKHMVDRYNIYYAYIPTKLNQRIHRAATSQVIVAPILCIFWLLFFSVLRLGPVHPITI 709          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSI 2176
            + G+P  + INVV +  L+ +F  LRK AW+YG LA L +  ++  +   + S  E +    S+T P +  +  ++ F   LL++      M D  ++ +CG DAV Y  FQR++I +++V+ +LSL +I+P+N  G+ L  +   F   T+ANV  +  FLW+H   +L + +      + H   ++++  E+ + T+MI ++P E CD  +I +HF EAYPS      +  ++V  LI L  ++  A +   +   + + +  ++ +  +LC  +   C  C  ++   +D  ++Y+    + T+ F  EKS  I+ K+L I FVTF +      + +DY      C  +  +  SS +  + S  W V++AP P DI+W+NL   G RWWL  +++N+ + +++  L+TPA+ +N  +    +  +E L +P++ QF P+L++   S ++P IVY+S    +HWT++ QN   M+K F +LV  V+ILPSLGL+S+     WLF  N      +K++C+F+ D GA F NY+IT+S IGT++ELLR+  L +Y  +   ++S+AE   + KS  ++FQFG+ YAWT+ +F+V   YS+  PIITPFGL Y +LKH+VDRYN+ +  +P+ ++  +H  A   + V  +L    +  +  LR G    ++I
Sbjct:   55 FGGVPTVLAINVVLWMFLLLIFSCLRKAAWDYGRLALLMENDSLTSLFYGEPSEKEKTP---SETSP-SDSDTKDMGFCSWLLSL----YYMKDGEIRSKCGIDAVTYLSFQRHIILLMTVVSLLSLAVILPVNFSGNLLGDSPQNFGRTTLANVSAKDNFLWLHSIFALVYFIITMLCMAHHAIRLEYREDEKVARTLMITSIPREICDPGLITKHFHEAYPSCTVTDNRFCFDVHKLIKLDLERRKAMKGRLYFTTKAQKEG-KIMIKTHLCAHI-FGCDICGFER---VDAEQYYSELEEKRTDEFNAEKSR-ISLKRLGIAFVTFRDERMTAVIVKDY--SRVRCRRRPQQ--SSITTVVQSHKWGVSYAPAPSDIIWENLSVCGSRWWLRCVLLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRSPVITQFLPTLLLWAFSVLLPFIVYYSAFFESHWTRSGQNQVTMHKCFLLLVFMVIILPSLGLSSLDLFFTWLFDVNFLEEKEVKFQCVFLPDNGAFFVNYVITSSLIGTSMELLRIPALTVYAFRLCFAKSQAERIHVKKSQAYEFQFGLEYAWTMCIFAVSMTYSITCPIITPFGLLYAILKHMVDRYNIYYAYIPTKLNQRIHRAATSQVIVAPILCIFWLLFFSVLRLGPVHPITI 709          

Query:   95 QCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL 2212
            +  R   Y  R  +T      + G+P  + ++ + +  L+ LF  LRK AW+YG LA + K  + E ++      S+  E + S    ++S  + + T      + L    ++ ++ L+++CG DA+ Y  FQR++I ++ V+ VLS+ II+P+N  G+ L +N+  F   TIAN+   +  LW+H T +  ++L   F   +H + + +K  +    T+ IN +  +  +E  I QHF  AY +   ++ ++ Y+V+ L+ L +++  AE + ++  +  ++ +   KV P  CG +C    CC  K C   + + +YT+    +   + TE+   +N K L + FVTF+N      + +D+   +   C  +    RS++S  L + +WTV +AP P+++ W++L   G +WWL  ++IN  + +++  L+TPA+ ++  +    ++ +E LNNP+V QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL S+    +WLF     A   +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS A+   + +   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHL DRYN+ +  +PS +   +H+ A   +    +L  + +  +  +R G +   S+  F+  ++ +++
Sbjct:   30 ETSRDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLGLLFLFSILRKLAWDYGRLALIAKD-DSESMSAVTSETSDRYERLAS----VSSSLDFDQT-DHGFCSWLTAVFRIKEDELREKCGEDAIHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGNLLENNAYSFGRTTIANLDVGNKLLWLHTTFAFLYLLLTVFSMRRHTSKMHYKENDLVKRTLFINGISKQ-GEEREIKQHFESAYSNCTVLETRICYDVAKLMQLNSERKKAERSKKYFIDLDKNASEPSKVNPKPCGHLC----CCAIKGCEQENAVSYYTNLEAEIRQQYRTEREK-VNKKPLGMAFVTFQNETITATILKDFNACKCQGCHCRREPRRSNHSKTLQTHNWTVMYAPHPQNVYWEHLSVGGAKWWLRCLLINCILFLLLFFLTTPAIIISTMDKFNVTKPVEYLNNPIVTQFFPTLLLWSFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLTSLDVFFRWLFDKKFLADAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAADRRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLADRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLSWLLFFSTVRSGFSAATSMFTFVVLIITIVV 724          

Query:   95 QCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGK---PLNIEHVAPRKESRSEHSEAIFSDTD-------PIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDY-MYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLL 2212
            +  R   Y  R  +T      + G+P  + ++ + +  L+ LF  LRK AW+YG LA + K     +++    R + R E+  A+ S+T         ++S  + + T      + L    ++ ++ L+++CG DA+ Y  FQR++I ++ V+ VLS+ II+P+N  G+ L +N+  F   TIAN+   +  LW+H T +  ++L   F   +H + + +K  +    T+ IN +  +  +E  I QHF  AY +   ++ ++ Y+V+ L+ L +++  AE + ++  +  ++ +   KV P  CG +C    CC  K C   + + +YT+    +   + TE+   +N K L + FVTF+N      + +D+   +   C  +    RS++S  L + +WTV +AP P+++ W++L   G +WWL  ++IN  + +++  L+TPA+ ++  +    ++ +E LNNP+V QF P+L++   SA++P IVY+S    AHWT++ +N   M+K +T L+  VL+LPSLGL S+    +WLF     A   +++EC+F+ D GA F NY+I ++FIG A++LLR+  L MY ++   +RS A+   + +   ++FQFG  YAW + +F+VV  YS+  PII PFGL Y+LLKHL DRYN+ +  +PS +   +H+ A   +    +L  + +  +  +R G +   S+  F+  ++ +++
Sbjct:   30 ETSRDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLGLLFLFSILRKLAWDYGRLALIAKDDSERSMDQRYCRLDGR-EYMSAVTSETSDRYERLASVSSSLDFDQT-DHGFCSWLTAVFRIKEDELREKCGEDAIHYLSFQRHIIGLLVVVGVLSVGIILPVNFSGNLLENNAYSFGRTTIANLDVGNKLLWLHTTFAFLYLLLTVFSMRRHTSKMHYKENDLVKRTLFINGISKQ-GEEREIKQHFESAYSNCTVLETRICYDVAKLMQLNSERKKAERSKKYFIDLDKNASEPSKVNPKPCGHLC----CCAIKGCEQENAVSYYTNLEAEIRQQYRTEREK-VNKKPLGMAFVTFQNETITATILKDFNACKCQGCHCRREPRRSNHSKTLQTHNWTVMYAPHPQNVYWEHLSVGGAKWWLRCLLINCILFLLLFFLTTPAIIISTMDKFNVTKPVEYLNNPIVTQFFPTLLLWSFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLTSLDVFFRWLFDKKFLADAKVRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAADRRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLADRYNMYYAYLPSKLDKKIHSGAVNQVVAAPILCLSWLLFFSTVRSGFSAATSMFTFVVLIITIVV 738          

Query:  158 YEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGR----SSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRG---TTDI--LSICCFLAFVLGLLLTFGR 2224
            + GIP  + ++   + +L+ LF  +R+K W+YG LA +           R+  R              A+    +  ++    + LP  V+M++E +K++CG DAV Y  FQR+LI ++ V+ V SL II+P+N+ G  L ++   F   TI N+   +  LW+H   ++ ++     +   H + +    KE    T+ ++ VP    +E + A HF EAYP+     V + Y+V+ L+ L  +++ A + L++    L+    R  + P LCG +C    CC G  C  +D IE+Y  +   L      E +  +    L I FVT +N   A  + +D+      C   +  GR    SS S  L  + W V+FAP PK + W+NL  RG+ W +  ++IN+ + +++  L+TP + +N ++    ++ +  LN+P++ QF P+L++   SA++P IVY+S    AHW+++++ +++M KL+  L+  VLILPSLGL S+    +WLF         +++EC+F+ D GA F NY+I A  +G+ ++LLRL  L +Y ++   +RS AE   + ++  ++F++G  Y WTL +F+V+ AYS+I PII PFGL Y+LLKHLVDR+NL    +P+ + + VH  A        ++    +  +  LR G   +T +  L + C   F+      FG 
Sbjct:   40 FGGIPLVLLLDFCVFIVLLVLFSIIREKFWDYGRLALVSDSDGFNESTHRRYGRMSS-----------AASNTEDFGYESGFCSWLPYIVRMDEEKIKEKCGIDAVHYLSFQRHLIILLVVITVTSLAIIMPVNMSGDLLKNDPQNFGRTTIGNLKTGNNLLWLHTVFAVIYLALTVVMLRVHTSQMKGLRKETARNTLFVSPVPKTATEEDVKA-HFVEAYPTCEVCAVTLGYDVARLMHLDKERLRAGKNLRYYERVLDKTGQRELINPRLCGHIC----CCSG--CVKVDAIEYYCGKEKFLLEEVRQE-AEIVPQHTLGIAFVTLKNEAMAKYILKDF--NAIECRGSTCCGREPQPSSQSRALKVNKWRVSFAPHPKSVYWENLSVRGFTWAVRYVLINLLLFLLLTFLTTPTIIINTFDKFNVTKPIYYLNSPIITQFFPTLLLWSFSALLPTIVYYSTLGEAHWSRSSEQLSMMRKLYFFLLFMVLILPSLGLTSLAVFFRWLFDKEFLNLGKLRFECVFLPDQGAFFVNYVIAAGLVGSGMDLLRLPGLLLYLIRMMLARSAAERKYVKQNQAYEFEYGAMYGWTLCVFTVIMAYSIICPIIVPFGLLYMLLKHLVDRHNLYFAYLPTRLDHQVHMGAVDQALAAPIICLIWLYFFSVLRAGFWTSTSLFTLVVLCVTVFICVGFTCFGH 716          

Query:   80 MSITLQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVTSINDDNDTIPLHNRNYGATVPNIR 2533
            MSIT QCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTI+ISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPLNLRGSFLSSNSSMFSSLTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHK GWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFTVLVITVLILPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGD QSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVTSINDDNDTIP+HNRNYGATVPNIR
Sbjct:    1 MSITPQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTIIISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPLNLRGSFLSSNSSMFSSLTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKHGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFTVLVITVLILPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDFQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVTSINDDNDTIPIHNRNYGATVPNIR 818          

Query:   92 LQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDPIASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLF-ITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVT 2461
            + CDRYNSY   K N   I  +YEGIP N+ INV+ Y ILI +FL LRK+AWNYG++AW  KP+NI  +A +       S+      +     EN    F ++    LPLF+K++D+ L++RCG DAVIYC+FQR L+ I +VM+V  L IIVPLNL G  LS ++S F +LTIAN+   S  L +H  V+   M+FVFFIS++ L  +D   KE+ S+++MI  VP E CDE +I QHFRE YP I+ +KVQ  YE+  +I+LY  KV AEEAL++C +ELEH N RVKV PN+ GR+C+ CKCC+   C PIDGIE+Y  EV R T LF  E+   +  KKLPIFFV+F++++ AL +RR+Y+YQNY C     K +SS S  LNSD+W V FAP+ KDILW+NLHK+GW+ W+ II+IN FV +++I LSTP++ +  WN+  F  +++K+ +   +QF PS+VMVLV+A MPL++  S+++SAH T+T Q+IA+MNKLFTVL +TVLILPSLGLNS  EL+  +F  TN++     KW+CIF+ DGGALFCNY+I+A FIG  LE+LR+G LF++ +K S ++S AE+N I +S+LW+F +G+ YAWTLALFS++SAYSVIVP+ITPFGL YL+ KH+VDRYN++HV +P+++ +SVH NA++L+Q+ L+ TQATVT+YV  R     ++ + C L F LG+LLT GR+V+R I SM+W+KYS+ +   D+   L++    + +  D+  F  ID +K  + +P     +   F +E++++ R SVT
Sbjct:    1 MACDRYNSY---KTNVSFIPNSYEGIPLNLLINVIVYLILIGVFLILRKRAWNYGDIAWFTKPINIMSLALKNRLSVTSSDKTEEHEEREKLMENSKNRFIDRFWKALPLFIKISDQDLEKRCGCDAVIYCKFQRMLLLISTVMVVAGLIIIVPLNLSGHSLSKDTSSFKTLTIANIGTGSKVLSVHLIVAFLLMIFVFFISNKFLKYVDDHGKEKVSYSLMITRVPLEACDESLIEQHFREIYPEISNMKVQRAYEIECMINLYISKVLAEEALEYCVDELEHFNRRVKVAPNVFGRMCIACKCCEAI-CKPIDGIEYYMKEVKRTTELFNEEQKKTLKEKKLPIFFVSFDSIEHALLIRREYIYQNYCCIKPYPKSQSSLSKILNSDNWKVIFAPISKDILWENLHKKGWKLWVKIILINSFVALLVITLSTPSMIIKFWND-NFQSQVKKIYSSWGSQFFPSIVMVLVTATMPLLICLSNEISAHQTRTKQSIAIMNKLFTVLTVTVLILPSLGLNSAQELMLQIFNRTNASIFTIFKWDCIFLYDGGALFCNYLISAGFIGMGLEILRIGPLFLFMIKMSTAKSEAENNGIAQSLLWEFPYGINYAWTLALFSIISAYSVIVPLITPFGLVYLVSKHMVDRYNMVHVFIPAVIESSVHVNASKLLQICLIFTQATVTIYVFFRAQGIPVIFVFCLLVFSLGILLTIGRSVRRSILSMAWIKYSEKADLTDQTSILKAAFSKI-RIPDKSIFSPIDHLKRSILIPQSDQGENHNFLIEQMQS-RMSVT 784          

Query:   92 LQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDP-IASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLNNPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTIKWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRWIFSMSWVKYSKSSKFMDRKGDLQSKPVDLEKDVDEDGFIMIDEIKERVFVPPQMTSDLDLFTLEKIKTARSSVT 2461
            + C RYNS+    N   + S  YEGIP N+ INVV Y +LI +FL LRK AWNYG + WL KP+N+   A  +   +   + + S+ D   A + NI           +PLF++M+D+ L++RCG DAVIYC FQR LI I SVM VL LTII+PLN  GS LS +SS F +LTIAN+   S  L  H ++S   M+FVFFIS+  L  +D K  ++   T+MI N+P E  DE +I QHF+EAYP+I+ +KVQ TY +  L  LYT KV AEEAL++C  + E  + RVKV  N  GR+C++C CC  K C PIDGI +YT EV R T LF  E+    +  KLPI FV+F++++ A+ +RR+Y+YQNY C  +  K +SS S +L SD+W V FAP+PKDILW+NLHK+G  +WL II IN+FV  ++I LSTP + L IWN   F +++ K+    ++QF PSL+MV+V+++MP++V W++ +SAHWT+T QNIA+MNKLF VLV+TVL LPSLGL+S  EL+   F  N T     KWEC+F+ADGG++FCNY+I+A FIG  LE+LRLG+L +   K S SRS+AE+  I++S+ W+F +G+ YAWTLALFS++S Y+VIVP+ITPFGL YL+ K+LVDRY++IHVN+P++V N VH NA +L+Q+ L+ TQATVT+YV+ R     I+   C  A  LG++L  GR+V+R I SM+W+KYS  S   D + D+         +VD     + D+I    FVP Q+  + +   ++K++   ++++
Sbjct:    1 MSCVRYNSFNYTVN---SFSDLYEGIPFNILINVVVYILLILIFLMLRKNAWNYGVIEWLTKPVNVMEEAADQSGLTSPEDCVESNGDNNRALQSNI-------FCRWIPLFIRMSDKCLRKRCGFDAVIYCMFQRMLILISSVMTVLCLTIILPLNFSGSLLSDDSSSFKTLTIANIEVGSTKLAFHLSISFILMIFVFFISNWFLKFVDTKIHKKTGVTLMITNIPIEVYDEQLIEQHFKEAYPTISNMKVQKTYAIGKLFDLYTNKVLAEEALEYCVTQYERFDRRVKVASNAFGRMCVSCNCCVAK-CQPIDGIGYYTEEVKRCTELFYKEQKLTFDSGKLPIVFVSFDSIEHAVVIRREYIYQNYCCIKQYPKSQSSLSMRLKSDNWKVIFAPIPKDILWENLHKQGLVFWLKIIFINLFVAFIVITLSTPPIILQIWNKF-FQDKIAKIWK-WISQFFPSLIMVIVTSIMPVLVCWANDMSAHWTRTKQNIAIMNKLFAVLVLTVLFLPSLGLSSAHELLWSFFNKNETFNKIFKWECLFLADGGSIFCNYLISAGFIGMGLEILRLGQLLLIIFKLSWSRSKAEERGIVQSLSWEFPYGINYAWTLALFSIISTYAVIVPLITPFGLFYLISKYLVDRYSMIHVNIPALVDNDVHFNAVKLLQICLIFTQATVTIYVSFRAEGFSIILGLCVAALCLGIILAIGRSVRRSILSMAWIKYSDISYITD-QSDISKDSRSSMGNVDVP---LDDDISIGSFVPIQIKPNKEESFIDKMQNRLAALS 774          

Query:   98 CDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVA-----------PRKESRSEHSEAIFSDTDPIASKENINLT--FKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILWQNLHKRGWRWWLPIIVINMFVGIVIIILSTPAVALNIWNNLKFSERLEKLN-NPLVAQFAPSLVMVLVSAVMPLIVYWSDQLSAHWTKTTQNIAVMNKLFXXXXXXXXXXPSLGLNSVPELIKWLFITNSTAPNTI--KWECIFMADGGALFCNYIITASFIGTALELLRLGELFMYTVKRSCSRSRAEDNAIIKSVLWDFQFGVGYAWTLALFSVVSAYSVIVPIITPFGLTYLLLKHLVDRYNLIHVNVPSIVHNSVHTNAAQLMQVGLVLTQATVTVYVALRRGTTDILSICCFLAFVLGLLLTFGRTVKRW 2239
            CDR N Y  R  N   +   +EGIPQN  IN+V   IL  LF FLRK AWN+G +A L K    E  +             K    E     F +   +     I+ T  F +   + L  F  ++D+ ++++ G+DA  Y  FQ+ LI    ++ V+SL +I+P+N+ G+      + F++ TI N+   S  +W+H  +S  +   +  I       +      E S T++I+ +P E     II  HF+EAYP      +Q  + +  LI L  Q+  A  A      +  +   R  ++P  CGR      CC       +D I++Y  E++ L      E   A + KK+ + FVTFE ++ A +V  DY      C   +    S+ S+ + S  WT+++AP    I W+NL     +W +  I+IN  + I + +L+TP  ALN+   L+ + + +K++ N ++ +F PS +M  VS ++P IVY+S+ +  HWTKT ++ AV+ K +T L+I VLILPSLG+ S+P  I WLF   +   NT    W CIF     A F NYIITA+FIGT  EL+R+ EL +Y   +   RS  E   I K+V+W+FQFG+ Y+W L +F+V   YS I P+I PFGL Y++ K+ VDRYN+      S +++ +H  A        +L Q  + +Y+ + +  ++++ I  F++ +L L L    T   W
Sbjct:    8 CDRVNIY--RITNDTAVIYGFEGIPQNFTINIVTSIILFVLFCFLRKNAWNHGRIALLTKNRRKEQSSTGYNIWNTVTLSEKNENEETDSTEFDEKTYLRRASVIDTTSQFDKGFFSWLKFFYVVSDKDIREKKGNDAYQYLMFQKYLIFTTFIITVISLMVILPVNMHGNGTKVKYNDFATTTILNLSSYSQMIWVHAVLSFLYFFGIIAIIWHFATTLQITTINEASNTLLIDGIPKESSFLSIILDHFKEAYPKCGIKDIQFAHNMRKLIHLNLQREIAIHAQNEAIRQYANTGIRRTMVPKFCGRFH---SCC----IEEVDVIDYYNDEILILEAQCQKEIVKAYD-KKIGVAFVTFETIEDARKVLEDYHSS---CSLLNYPQTSALSNDIKSAYWTISYAPPSNVINWENLCHPYKKWLIKAILINSILFIFLFMLTTPTYALNV---LQLNFQSKKISMNIVLNRFLPSFIMWAVSTLLPFIVYYSEVMIGHWTKTDEHTAVIIKTYTFLIIMVLILPSLGIASLPSFINWLFSIQNIQLNTFYFHWLCIFAPGNCAFFVNYIITAAFIGTISELIRIPELIIYLYYQIVVRSSVEMWGIRKNVIWEFQFGLCYSWILCVFTVTVTYSFICPLIVPFGLIYIIFKYSVDRYNIYFAYERSFINSKIHRLAMSFTVFAFLLLQINLLIYLNVNKVKSNLVYIFVFISCILSLTLFMFFTFYGW 721          

Query:   92 LQCDRYNSYIPRKNNTFTISTAYEGIPQNVFINVVAYTILISLFLFLRKKAWNYGNLAWLGKPLNIEHVAPRKESRSEHSEAIFSDTDP-IASKENINLTFKEKLLNILPLFVKMNDEALKQRCGSDAVIYCRFQRNLIAIVSVMMVLSLTIIVPXXXXXXXXXXXXXXXXXXTIANVPKESPFLWIHFTVSLGFMLFVFFISSQHLNNIDFKAKEEPSFTVMINNVPTEFCDEMIIAQHFREAYPSINPIKVQVTYEVSTLISLYTQKVAAEEALQFCYEELEHDNHRVKVIPNLCGRVCLTCKCCQGKKCTPIDGIEFYTHEVMRLTNLFTTEKSNAINYKKLPIFFVTFENLDQALRVRRDYMYQNYLCFNKSMKGRSSYSHQLNSDDWTVTFAPMPKDILW 1303
            + C RYNS+    N   + S  YEGIP N+ INVV Y +LI +FL LRK AWNYG + WL KP+N+   A  +   +   + + S+ D   A + NI           +PLF++M+D+ L++RCG DAVIYC FQR LI I SVM VL LTII+PLN  GS LS +SS F +LTIAN+   S  L  H ++S   M+FVFFIS+  L  +D K  ++   T+MI N+P E  DE +I QHF+EAYP+I+ +KVQ TY +  L  LYT KV AEEAL++C  + E  + RVKV  N  GR+C++C CC   KC PIDGI +YT EV R T LF  E+    +  KLPI FV+F++++ A+ +RR+Y+YQNY C  +  K +SS S +L SD+W V FAP+PKDILW
Sbjct:    1 MSCVRYNSFNYTVN---SFSDLYEGIPFNILINVVVYILLILIFLMLRKNAWNYGVIEWLTKPVNVMEEAADQSGLTSPEDCVESNGDNNRALQSNI-------FCRWIPLFIRMSDKCLRKRCGFDAVIYCMFQRMLILISSVMTVLCLTIILPLNFSGSLLSDDSSSFKTLTIANIEVGSTKLAFHLSISFILMIFVFFISNWFLKFVDTKIHKKTGVTLMITNIPIEVYDEQLIEQHFKEAYPTISNMKVQKTYAIGKLFDLYTNKVLAEEALEYCVTQYERFDRRVKVASNAFGRMCVSCNCCVA-KCQPIDGIGYYTEEVKRCTELFYKEQKLTFDSGKLPIVFVSFDSIEHAVVIRREYIYQNYCCIKQYPKSQSSLSMRLKSDNWKVIFAPIPKDILW 394