Integrator complex subunit 4

Overview


Name	Integrator complex subunit 4
Smed ID	SMED30002140
Length (bp)	2646

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Integrator complex subunit 4 (SMED30002140) t-SNE clustered cells

Violin plots show distribution of expression levels for Integrator complex subunit 4 (SMED30002140) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Integrator complex subunit 4 (SMED30002140) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Integrator complex subunit 4 (SMED30002140) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002140

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30002140	SMESG000012359.1	SmedASXL_015991	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30002140	SMESG000012359.1	SmedASXL_015991	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of Integrator complex subunit 4 vs. Ensembl Human
Match: INTS4 (integrator complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:25048])

HSP 1 Score: 200.675 bits (509), Expect = 1.075e-52
Identity = 144/454 (31.72%), Postives = 232/454 (51.10%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFLDPLSHF------PCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPELIFEDSDFIDEPVA 1477
            ++L  T   VR +CL+++G  L  L            + +   ++  +  D D RVR  A +  +Q  +RG  L   Q I +     L+D  ++V + +++L+  ++ +  +  V   S+  + RL D AF  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E+VDT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  +     I +N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DRDSIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L       +   V+
Sbjct:  157 KHLTDTSHGVRNKCLQLLGN-LGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKL--HQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSS-GRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVS 600

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Human
Match: INTS4 (integrator complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:25048])

HSP 1 Score: 158.303 bits (399), Expect = 1.747e-40
Identity = 116/359 (32.31%), Postives = 188/359 (52.37%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFLDPLSHF------PCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWR 1204
            ++L  T   VR +CL+++G  L  L            + +   ++  +  D D RVR  A +  +Q  +RG  L   Q I +     L+D  ++V + +++L+  ++ +  +  V   S+  + RL D AF  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E+VDT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  +     I +N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DRDSIW+
Sbjct:  157 KHLTDTSHGVRNKCLQLLGN-LGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKL--HQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSS-GRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTM---RKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWK 505

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BLAST of Integrator complex subunit 4 vs. Ensembl Celegans
Match: W04A4.5 (pep chromosome:WBcel235:I:13663462:13674997:1 gene:WBGene00012234.1 transcript:W04A4.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:W04A4.5)

HSP 1 Score: 122.094 bits (305), Expect = 5.585e-28
Identity = 110/427 (25.76%), Postives = 200/427 (46.84%), Query Frame = 2

Query:  287 DHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKI------IKKSVF--DRTNAINK-LFWI---------DELSNFARKSRISEQVDTPEDAMAMG----------------------GINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLS--IASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI 1441
            D D RVR++A E  +  L   F L   +    L +T + D + ++   ++KL++  AN + + E I  +NK   +L D AF  +  A++     VR  AAK +   + VSE L+ +TL+K +M+         +++S+F   +  + N+   W          +    ++R   ++  V + E+    G                      G  GA +  LED+F ++R  A+ ++G+L+     FAVS  + L DM  D++  VR  ++  L+  IA G      + ++QL+++   L +     R+++ +LL   +    + +   V+ LL  L+ +  D+D I+ C A +G+NH   VQ  + SLL +H     ++ S  D  Y+  L+MV+NA+    S+    P  V  +  +L+   P L+
Sbjct:  286 DRDFRVRKSAAEGLLA-LSNVFKLS--KATYQLAKTHMADSDSDIRIAAIKLLIFYANRRGE-EEIEGTNK---KLYDDAFSSICDAINDIEIGVRVEAAKKLGDFEQVSEELIYQTLDKKMMRSTTNQQVVKVQQSLFALSKKASTNRDRRWKFAKKAPKMQESRGGWSRGKELNASVPSEEEKKKNGVEGAEKNDDDDDNEEEESIIPHGACGAFVSALEDEFMDVRKAAVYSLGRLACTRPTFAVSALEYLADMFNDEMADVRLDAINALTPLIAHG-----QINSEQLNVISKCLDDAMPEARQAMRELLKRAQFVDLNCIEMCVKALLSCLKRFPKDKDEIYGCMADIGKNHGVQVQSIMRSLLDIHLIFHTRESSIEDQEYVGKLIMVLNAAAFQPSMVHFMPEFVHRHYRFLRNASPNLV 700

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BLAST of Integrator complex subunit 4 vs. Ensembl Fly
Match: IntS4 (gene:FBgn0026679 transcript:FBtr0071234)

HSP 1 Score: 188.348 bits (477), Expect = 8.076e-49
Identity = 130/432 (30.09%), Postives = 221/432 (51.16%), Query Frame = 2

Query:  158 NLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKS--RISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSK--SDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI 1441
             L S  +H +   + VIG+F   +     G  +    + ++    D+ VR  A    +   +RG  LP   ++       + D  + V   +++LV  + N   D  + S   + + R+ D AF  V  AL   S ++R +AA+L+  +  VS   L +TL+K +M +   K++  +R     +L    E S+  R +     E +D    ++   G  GALI+GLED+F E+R  A+ ++ KL++    FAV+  D LVDM  D+IE VR  ++ +L+    I  ++ LR DQL+I+L  L + S ++R  +H +L  CR+++   L+ +V+ LL  L  Y  DR+S + C   +G+ HP LV      LL +HP+  F+ P +   D AY+ VL++V NA+  L  I +  P+    +  YL++ +P L+
Sbjct:  224 QLRSGSAHTQKNAMLVIGRFATKME----GERHYVWKLAFYIDSQDSSVRAQALHALLTLGERGSQLPA--VLYKRAVEAMKDDYECVRKEALQLVFMLGNRHPDYILPSDRQQEELRMIDAAFSKVCEALCDLSLQIRVLAAELLGGMTAVSREFLHQTLDKKLMSNLRRKRTAHERGA---RLVASGEWSSGKRWADDAPQEHLDAQSISIIASGACGALIHGLEDEFLEVRTAAVASMCKLALSRPDFAVTSLDFLVDMFNDEIEDVRLKAIYSLT---AIAKHIVLREDQLEIMLGSLEDYSVDVREGLHLMLGACRVSTQTCLLMVVQKLLDVLAKYPQDRNSTYACMRKIGQKHPHLVMAVAVHLLYVHPF--FETPERDVEDPAYLCVLILVFNAAEHLVPIISLLPTATHRHYAYLRDSMPNLV 641

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BLAST of Integrator complex subunit 4 vs. Ensembl Zebrafish
Match: ints4 (integrator complex subunit 4 [Source:ZFIN;Acc:ZDB-GENE-120215-81])

HSP 1 Score: 199.519 bits (506), Expect = 2.243e-52
Identity = 143/447 (31.99%), Postives = 235/447 (52.57%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIG---QFLDPLSH---FPCGSS-------NTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKS--RISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            ++L+STY  VR +CL+++G       PLS       G+        +   ++  + QD D RVR  A +  +Q  +RG  +   Q I +     L+D  ++V + ++++V  ++ +  +  V   S+  + RL D +F  +   +S  S  VR  AAKL+  +  VS   L +TL+K +M D   K++  +R     +L+   E S+  R +     E+VDT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR   ++++ +   I  ++TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+S+W+C   +G  HP LV   +  LL  HPY    +P   D AYI VL++V NA++   ++   F  H   +  YL++    LVP L
Sbjct:  159 KHLSSTYFGVRNKCLQLLGCLGTVDKPLSKETDTGAGAGAQTSAVRDVLSLISDYFQDQDPRVRTAAIKAMLQLHERGMKIQ--QTIYNQACKLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDSFGKICHMVSDGSWVVRVQAAKLLGSMHQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYASGEFSSGRRWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCSLAQSSRSFAEKCLDFLVDMFNDEIEEVR---LQSIHVLRQISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLSKYPTDRNSVWKCLKFLGARHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAQSCPTMPALFSDHTFRHYAYLRDSLSHLVPHL 597

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Xenopus
Match: cfap54 (cilia and flagella associated 54 [Source:Xenbase;Acc:XB-GENE-6045344])

HSP 1 Score: 193.741 bits (491), Expect = 1.776e-50
Identity = 142/453 (31.35%), Postives = 233/453 (51.43%), Query Frame = 2

Query:  143 MQVV----RNLNSTYSHVRMQCLKVIGQF--LDPLSHFPCGSSNTFDVVQ----WFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGIN-------GALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            MQ+V    ++L+ T   VR +CL+++G    ++  +     ++ T DV +    +F  D D RVR  A +  +Q  +RG  L   Q + +     L D  ++V + + +L+  ++ +  +  V   S+  + RL D AF      +S  S  VR  A KL+  +  VS   L +TL+K +M D   K++  +R     +L+   E S+  +        D P++ +  G +N       GA ++GLED+ YE+R+ A++++  L+  S  FA  C D LVDM  D+IE VR  S+  +     I  N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+SIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  152 MQLVDVACKHLSDTSHGVRNKCLQLLGCLGSVEASTAKEVENAVTKDVQKIIGDYFI-DQDPRVRTAAIKAMLQLHERGLKLQ--QAMYNQACKLLTDDYEQVRSAAAELIWVLSQLFPESIVPIPSSNEEIRLVDDAFGKACHMVSDGSWVVRVKACKLLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSSGRKWGD-----DAPKEELDTGAVNLIDSGACGAFVHGLEDEMYEVRIAAVESLCLLARSSAPFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISDNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKECIQLALVELLKNLSKYPTDRESIWKCLKFLGSRHPTLVLSLVPELLSTHPFFDTPEPDMDDPAYIAVLVLIFNAAKCCPTMPALFSDHTFRHYAYLRDSLSHLVPAL 590

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Xenopus
Match: cfap54 (cilia and flagella associated 54 [Source:Xenbase;Acc:XB-GENE-6045344])

HSP 1 Score: 193.356 bits (490), Expect = 2.402e-50
Identity = 141/452 (31.19%), Postives = 232/452 (51.33%), Query Frame = 2

Query:  143 MQVV----RNLNSTYSHVRMQCLKVIGQF--LDPLSHFPCGSSNTFDV---VQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGIN-------GALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            MQ+V    ++L+ T   VR +CL+++G    ++  +     ++ T DV   +  +  D D RVR  A +  +Q  +RG  L   Q + +     L D  ++V + + +L+  ++ +  +  V   S+  + RL D AF      +S  S  VR  A KL+  +  VS   L +TL+K +M D   K++  +R     +L+   E S+  +        D P++ +  G +N       GA ++GLED+ YE+R+ A++++  L+  S  FA  C D LVDM  D+IE VR  S+  +     I  N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+SIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  135 MQLVDVACKHLSDTSHGVRNKCLQLLGCLGSVEASTAKEVENAVTKDVQKIIGDYFIDQDPRVRTAAIKAMLQLHERGLKLQ--QAMYNQACKLLTDDYEQVRSAAAELIWVLSQLFPESIVPIPSSNEEIRLVDDAFGKACHMVSDGSWVVRVKACKLLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSSGRKWGD-----DAPKEELDTGAVNLIDSGACGAFVHGLEDEMYEVRIAAVESLCLLARSSAPFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISDNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKECIQLALVELLKNLSKYPTDRESIWKCLKFLGSRHPTLVLSLVPELLSTHPFFDTPEPDMDDPAYIAVLVLIFNAAKCCPTMPALFSDHTFRHYAYLRDSLSHLVPAL 573

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Xenopus
Match: cfap54 (cilia and flagella associated 54 [Source:Xenbase;Acc:XB-GENE-6045344])

HSP 1 Score: 193.741 bits (491), Expect = 2.429e-50
Identity = 142/453 (31.35%), Postives = 233/453 (51.43%), Query Frame = 2

Query:  143 MQVV----RNLNSTYSHVRMQCLKVIGQF--LDPLSHFPCGSSNTFDVVQ----WFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGIN-------GALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            MQ+V    ++L+ T   VR +CL+++G    ++  +     ++ T DV +    +F  D D RVR  A +  +Q  +RG  L   Q + +     L D  ++V + + +L+  ++ +  +  V   S+  + RL D AF      +S  S  VR  A KL+  +  VS   L +TL+K +M D   K++  +R     +L+   E S+  +        D P++ +  G +N       GA ++GLED+ YE+R+ A++++  L+  S  FA  C D LVDM  D+IE VR  S+  +     I  N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+SIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  151 MQLVDVACKHLSDTSHGVRNKCLQLLGCLGSVEASTAKEVENAVTKDVQKIIGDYFI-DQDPRVRTAAIKAMLQLHERGLKLQ--QAMYNQACKLLTDDYEQVRSAAAELIWVLSQLFPESIVPIPSSNEEIRLVDDAFGKACHMVSDGSWVVRVKACKLLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSSGRKWGD-----DAPKEELDTGAVNLIDSGACGAFVHGLEDEMYEVRIAAVESLCLLARSSAPFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISDNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKECIQLALVELLKNLSKYPTDRESIWKCLKFLGSRHPTLVLSLVPELLSTHPFFDTPEPDMDDPAYIAVLVLIFNAAKCCPTMPALFSDHTFRHYAYLRDSLSHLVPAL 589

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Mouse
Match: Ints4 (integrator complex subunit 4 [Source:MGI Symbol;Acc:MGI:1917164])

HSP 1 Score: 200.675 bits (509), Expect = 9.319e-53
Identity = 146/441 (33.11%), Postives = 229/441 (51.93%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQF--LDPLSHFPCGSSNTFDVVQWFTQDH----DARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            ++L  T   VR +CL+++G    L+         S   DV Q    DH    D RVR  A +  +Q  +RG  L   Q I +     L+D  ++V + +++L+  ++ +  +  V   S+  + RL D AF  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E++DT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  +     I +N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DRDSIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  158 KHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGSAARDV-QKIIGDHFSDQDPRVRTAAIKAMLQLHERGLKL--HQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSS-GRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPAL 588

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BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q96HW7|INT4_HUMAN (Integrator complex subunit 4 OS=Homo sapiens OX=9606 GN=INTS4 PE=1 SV=2)

HSP 1 Score: 200.675 bits (509), Expect = 5.163e-52
Identity = 144/454 (31.72%), Postives = 232/454 (51.10%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFLDPLSHF------PCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPELIFEDSDFIDEPVA 1477
            ++L  T   VR +CL+++G  L  L            + +   ++  +  D D RVR  A +  +Q  +RG  L   Q I +     L+D  ++V + +++L+  ++ +  +  V   S+  + RL D AF  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E+VDT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  +     I +N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DRDSIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L       +   V+
Sbjct:  157 KHLTDTSHGVRNKCLQLLGN-LGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKL--HQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSS-GRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVS 600

[Close]

BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q8CIM8|INT4_MOUSE (Integrator complex subunit 4 OS=Mus musculus OX=10090 GN=Ints4 PE=1 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 6.519e-52
Identity = 146/441 (33.11%), Postives = 229/441 (51.93%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQF--LDPLSHFPCGSSNTFDVVQWFTQDH----DARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            ++L  T   VR +CL+++G    L+         S   DV Q    DH    D RVR  A +  +Q  +RG  L   Q I +     L+D  ++V + +++L+  ++ +  +  V   S+  + RL D AF  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E++DT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  +     I +N+TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DRDSIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  158 KHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGSAARDV-QKIIGDHFSDQDPRVRTAAIKAMLQLHERGLKL--HQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSS-GRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPAL 588

[Close]

BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q68F70|INT4_XENLA (Integrator complex subunit 4 OS=Xenopus laevis OX=8355 GN=ints4 PE=2 SV=1)

HSP 1 Score: 199.519 bits (506), Expect = 1.477e-51
Identity = 140/445 (31.46%), Postives = 229/445 (51.46%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFLDPLSHFPCG------SSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGIN-------GALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            ++L+ T   VR +CL+++G  L  +   P        + +   ++  +  D D RVR  A +  +Q  +RG  L   Q + +     L D  ++V + +++L   ++ + S+  V   S+  + RL D AF  V   +S  S  VR  A KL+  +  VS   L +TL+K +M D   K++  +R     +L+   E S+  +        D P++ +  G +N       GA ++GLED+ YE+R+ A++++  L+  S  FA  C D LVDM  D+IE VR  S+  +     I  N+TLR DQLD VL+VL +KS ++R ++H+LL    +++   +   +  LLKNL  Y  DR+SIW+C   +G  HP LV   +  LL  HP+    +P   D AYI VL+++ NA++   ++   F  H   +  YL++    LVP L
Sbjct:  159 KHLSDTSHGVRNKCLQLLG-CLGSVEASPAKEVENAVAKDVQKIIGDYFIDQDPRVRTAAIKAMLQLHERGLKLQ--QAMYNQACKLLTDDYEQVRSAAVELSWVLSQLYSESIVPIPSSNEEIRLVDDAFGKVCHMVSDGSWVVRVQACKLLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYSSGEFSSGRKWGD-----DAPKEELDTGAVNLIDSGACGAFVHGLEDEMYEVRIAAVESLCLLARSSAPFAEKCLDFLVDMFNDEIEEVRLQSIHTMR---KISDNITLREDQLDTVLAVLEDKSRDIREALHELLCCTNVSTKECIQLALVELLKNLSKYPTDRESIWKCLKFLGSRHPTLVLSLVPELLSTHPFFDTPEPDMDDPAYIAVLVLIFNAAKCCPTMPALFSDHTFRHYTYLRDSLSHLVPAL 589

[Close]

BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q9W3E1|INT4_DROME (Integrator complex subunit 4 OS=Drosophila melanogaster OX=7227 GN=IntS4 PE=1 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 8.095e-48
Identity = 130/432 (30.09%), Postives = 221/432 (51.16%), Query Frame = 2

Query:  158 NLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKS--RISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSK--SDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI 1441
             L S  +H +   + VIG+F   +     G  +    + ++    D+ VR  A    +   +RG  LP   ++       + D  + V   +++LV  + N   D  + S   + + R+ D AF  V  AL   S ++R +AA+L+  +  VS   L +TL+K +M +   K++  +R     +L    E S+  R +     E +D    ++   G  GALI+GLED+F E+R  A+ ++ KL++    FAV+  D LVDM  D+IE VR  ++ +L+    I  ++ LR DQL+I+L  L + S ++R  +H +L  CR+++   L+ +V+ LL  L  Y  DR+S + C   +G+ HP LV      LL +HP+  F+ P +   D AY+ VL++V NA+  L  I +  P+    +  YL++ +P L+
Sbjct:  224 QLRSGSAHTQKNAMLVIGRFATKME----GERHYVWKLAFYIDSQDSSVRAQALHALLTLGERGSQLPA--VLYKRAVEAMKDDYECVRKEALQLVFMLGNRHPDYILPSDRQQEELRMIDAAFSKVCEALCDLSLQIRVLAAELLGGMTAVSREFLHQTLDKKLMSNLRRKRTAHERGA---RLVASGEWSSGKRWADDAPQEHLDAQSISIIASGACGALIHGLEDEFLEVRTAAVASMCKLALSRPDFAVTSLDFLVDMFNDEIEDVRLKAIYSLT---AIAKHIVLREDQLEIMLGSLEDYSVDVREGLHLMLGACRVSTQTCLLMVVQKLLDVLAKYPQDRNSTYACMRKIGQKHPHLVMAVAVHLLYVHPF--FETPERDVEDPAYLCVLILVFNAAEHLVPIISLLPTATHRHYAYLRDSMPNLV 641

[Close]

BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Match: sp|Q54LH5|INT4_DICDI (Integrator complex subunit 4 homolog OS=Dictyostelium discoideum OX=44689 GN=ints4 PE=3 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 2.991e-27
Identity = 75/232 (32.33%), Postives = 132/232 (56.90%), Query Frame = 2

Query:  797 GGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPELIFEDSDFIDEPVAK 1480
             G+ GA I GLED+FYE+R  AI ++ +LS+++++FA    D LVD+  D+IE VR +S+ +L     I +N+ ++ +QL I+L+ L   S   R+S+H+LL+   L++   L    + LL NL  Y  D  SI+    I+G+ +P   +  ++ LL++ P     +P+  D  Y+ V+++V+N+  K  +I +  PS    + +Y ++      P+ + +DS+ I  P  K
Sbjct:  490 SGVIGAFIQGLEDEFYEVRSSAIDSMCELSVRNDEFAQKNIDFLVDIFNDEIESVRINSINSL---RKIGNNVVIKEEQLHIILANLESSSKEERQSLHRLLTSIHLSNYSCLHATTQALLMNLSRYPYDIHSIFETLKIIGQTNP-FTEFIVDDLLRIDPKFASVEPNMDDIFYVAVMVLVLNSCIKNRNILSLLPSFSFQHHLYFKDKYPKYFPQNLQKDSNIILAPTLK 717

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BLAST of Integrator complex subunit 4 vs. TrEMBL
Match: A0A094ZKC6 (Integrator complex subunit 4 (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_01502 PE=4 SV=1)

HSP 1 Score: 280.796 bits (717), Expect = 1.723e-80
Identity = 195/567 (34.39%), Postives = 299/567 (52.73%), Query Frame = 2

Query:   62 VLPP---EEYEILKEINSISSCDDINNFQIMQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWL--------DRGFPLP-----------------------NFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQ-----SDLEVISQSNKLKSR-----------LADKAFCCVACALSHASSRVRQMAAKLMSCI-KDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDT---PEDAMAM--GGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI--------FEDSDFIDEPVAKQ-MKYDDNIDASHQDAVSRQDLYSYLIDTI 1567
             LPP   +E  +L  IN   +C                   +HVR  CL ++  +  P      GS+   +VV W T D D RVR+ +F   + WL           F  P                       N + +      GL D E+ V  TS+ ++ K++ I      +D+ V S ++ + S+           L D AF  V C L   S  VRQ+AA +M+ + K V+E  LL+TLEKTVM D+ +++S+ +  N  +K       +N + +S +  ++ T     D++ +   G NGA+I GLEDD++EIR   + T+  ++  + +FA++CQDLLVDMLTDDI+ VR ++V  LS+   +   + ++++Q+ I+ S L+E SG +RR +H LLS CRLASA  L+ L++GLL+NLR Y  DRD++WRC+A VGRNHP  V+  L+SLL+ H +L   +P K D AY+TVLL+V+NA   +  +   FP HV + +IYLQEL+P L+        F++   +D P  K  +  D  ++AS    +    LY ++  TI
Sbjct:   25 ALPPTATQELSVLGVINEAFACPS-----------------AHVRSGCLDLLAGWNSPQICLSAGSAG--EVVLWHTADGDPRVRDRSFHCLLTWLCSLNAVLKSSEFSRPGKAKYFNNHKESAKKELTGWFEANLESVYSAACQGLLDNEELVRRTSLHVLGKLSTIWPHRSLTDVPVFSLNSLVSSKIFLDSDLEETQLVDDAFIRVCCRLQDPSRSVRQLAAHIMADLAKFVTENCLLQTLEKTVMSDRQVRRSMMEGDNK-SKDRKNKSNNNNSLRSTVDNRLQTKNLTSDSINLISTGCNGAIISGLEDDYFEIRCTTLATVTHIASLNTRFALNCQDLLVDMLTDDIQDVRLAAVRALSV---VGDKVPVKSEQVSIITSALAEGSGRIRRRLHHLLSQCRLASAPCLISLLDGLLQNLRRYPEDRDNLWRCAASVGRNHPIFVETCLSSLLRTHSWLNGPEPVKEDPAYLTVLLLVLNAEPSIPGMLAKFPRHVASTKIYLQELLPSLLPKTVVNDEFQNVSPLDVPNKKLCLSTDGTLNAS--TIMEHCSLYKFIASTI 566

[Close]

BLAST of Integrator complex subunit 4 vs. TrEMBL
Match: A0A4Z2CRX5 (Integrator complex subunit 4 OS=Schistosoma japonicum OX=6182 GN=EWB00_008063 PE=4 SV=1)

HSP 1 Score: 283.878 bits (725), Expect = 2.023e-79
Identity = 195/563 (34.64%), Postives = 303/563 (53.82%), Query Frame = 2

Query:   65 LPP---EEYEILKEINSISSCDDINNFQIMQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWL---DRGFPLPN--------------------FQLIIDLLET----GLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKS-----------------RLADKAFCCVACALSHASSRVRQMAAKLMSCI-KDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWI-DELSNFAR-KSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI----FEDSDFIDEPVAK-QMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVL 1588
            LPP   +E  +L  IN   +C                   +H+R  CL ++  +  P +    GS+   +VV W T+D+D RVR+ AF   + WL   +  F  PN                    F+  ++ + +    GL D E+ V  TS+ ++ K++ I     ++       +                 RL D AF  V C +   S  VRQ+AA +M+ + K V+E  LL+TLEKTVM DK I++S+ ++ N   +   +   L N A+ KS  SE ++     +   G NGA+I GLEDD++EIR   + T+  ++  + +FA+SCQDLLVDMLTDDI+ VR ++V  LS    +   + ++++Q+ I+ S L+E SG +RR +H LLS CRLASA  L+ L++GLL+NLR Y  DRD++WRC+A VGRNHP  V+  L+SLL+ H +L   +P K D AY+TVLL+V+NA   +  +   FP HV + +IYLQEL+P L+    F++   +D    K ++  D ++ +S  + V    L+ +   TI ++ ++ 
Sbjct:   16 LPPIATQELSVLGVINEAFTCSS-----------------AHIRSGCLDLLAAWNSPHTCLSAGSAG--EVVLWHTRDNDPRVRDRAFHCLLTWLCSLNTSFK-PNGKTKYFGNFKESTKKELTLWFETNLESVYSAACHGLLDNEELVRRTSLHVLGKLSTIWPHHSLVEVPVSSLNSSVVSSKPCFDADLEEIRLVDDAFIRVCCRIQDPSRSVRQLAAYVMADLAKFVTENCLLQTLEKTVMSDKQIRRSMIEQDNKSRRGNNMRSTLDNRAQTKSLTSESIN-----LISSGSNGAIISGLEDDYFEIRCTTLATVTHIASINTRFALSCQDLLVDMLTDDIQDVRLAAVRALS---AVGDKVPVKSEQVSIITSALAEGSGRIRRRLHYLLSHCRLASAPCLISLLDGLLQNLRRYPEDRDNLWRCAASVGRNHPVFVETCLSSLLRTHSWLNGPEPVKEDPAYLTVLLLVLNAEPSVPGMLAKFPRHVTSTKIYLQELLPSLLPKTEFQNVSALDLLNKKFELDVDSSLKSSSINMVEHCSLHRFTASTICRIRQLF 550

[Close]

BLAST of Integrator complex subunit 4 vs. TrEMBL
Match: A0A5J4NDU5 (Integrator complex subunit 4 OS=Paragonimus westermani OX=34504 GN=DEA37_0001653 PE=4 SV=1)

HSP 1 Score: 266.929 bits (681), Expect = 4.581e-76
Identity = 171/459 (37.25%), Postives = 247/459 (53.81%), Query Frame = 2

Query:  161 LNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGF-------PLPNFQLII------------DLLE----TGLNDREDEVVNTSMKLVVKMANIQSDLEVISQS-------NKLKSR-----LADKAFCCVACALSHASSRVRQMAAKLMS-CIKDVSEALLLETLEKTVMKDKIIKKSVFDR------TNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEI 1411
              S  +HVR +C+ ++     P      G +   D+V W T D DARVRE AF     WL           PL N Q ++            D +      GL+D E    +TS+ L+ +++      E+           + LK+      L D AF  V   L     +VRQ+AAKL+S   K VS+  L++TLEKTVM D+ +++S  DR      TN  N+    D L+   R S +          +   G++GA+I GLEDDF+E+R   + T+  ++  S +FA +CQDLLVDMLTDDI+ VR ++V  L     +   M L ++Q+ I+ S L+E SG +RR +HQLLS CRLASA  L+ L++GLL+NLR Y  DRDS+WRC+A VGR HP  V+  L+SLL+ H +L   +P++ D AY+TVLL+V+NA      +   FP H+   ++
Sbjct:   52 FGSLSAHVRAKCVDLLAARAGPKLWLRAGYAG--DLVLWHTDDGDARVRERAFACLRVWLSPSAEKMAVTQPLTNQQALLHQERLSWSKSNLDAIYYAACRGLSDVELITRHTSLLLLAQLSTTWPHYELTDPPAIGPVSISTLKTSTEPIYLIDDAFARVCTRLHDPGRQVRQLAAKLLSDLAKSVSDDYLIQTLEKTVMSDRQVRQSALDRGPLLLPTNQKNR---SDPLTISNRSSSVGSA------GIMSAGLSGAIISGLEDDFFEVRCATLSTVTHVASLSTRFASNCQDLLVDMLTDDIQEVRLAAVRALG---AVGDQMPLHSEQVAIITSALAEGSGRIRRRLHQLLSRCRLASAPCLISLLDGLLRNLRRYPQDRDSLWRCAASVGRRHPVFVETCLSSLLRTHSWLSGPEPNREDPAYLTVLLLVLNAEPGAPGMPAKFPRHLAATKV 496

[Close]

BLAST of Integrator complex subunit 4 vs. TrEMBL
Match: G4VLH2 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_123130 PE=4 SV=1)

HSP 1 Score: 275.789 bits (704), Expect = 1.205e-74
Identity = 196/575 (34.09%), Postives = 297/575 (51.65%), Query Frame = 2

Query:   62 VLPP---EEYEILKEINSISSCDDINNFQIMQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWL--------DRGFPLP-----------------------NFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQ-----SDLEVISQSNKLKSR-----------LADKAFCCVACALSHASSRVRQMAAKLMSCI-KDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNF-ARKSRISEQVDTPEDAMAM--GGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI--------FEDSDFIDEPVAK---QMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVLF 1591
             LPP   +E  +L  IN   +C                   +HVR  CL ++  +  P      GS+   +VV W T D D RVR+ +F   + WL           F  P                       N + +      GL D E+ V  TS+ ++ K++ I      +D+ V S ++ + S+           L D AF  V C L   S  VRQ+AA +M+ + K V+E  LL+TLEKTVM D+ +++S+ +  N           +N  +     S+  +   D++ +   G NGA+I GLEDD++EIR   + T+  ++  + +FA++CQDLLVDMLTDDI+ VR ++V  LS A G K  + ++++Q+ I+ S L+E SG +RR +H LLS CRLASA  L+ L++GLL+NLR Y  DRD++WRC+A VGRNHP  V+  L+SLL+ H +L   +P K D AY+TVLL+V+NA   +  +   FP HV + +IYLQEL+P L+        F++   +D P  K       DD+   +    +    LY ++  TI ++ K+  
Sbjct:   15 ALPPTATQELSVLGVINEAFACPS-----------------AHVRSACLDLLSGWNSPQICLSAGSAG--EVVLWHTADGDPRVRDRSFHCLLTWLCSLNAVLKSSEFSRPGKAKYFNNHKESVRKELTGWFEANLESVYSAACQGLLDNEELVRRTSLHVLGKLSTIWPHHSLTDVPVFSLNSLVSSKICLDSDLEETQLVDDAFIRVCCRLQDPSRSVRQLAAHIMADLAKFVTENCLLQTLEKTVMSDRQVRRSMIESDNKSKNKKNKSNNNNLRSTMDNHSQTKNLTSDSINLMSTGCNGAIISGLEDDYFEIRCTTLATVTHIASLNTRFALNCQDLLVDMLTDDIQDVRLAAVRALS-AVGDK--VPVKSEQVSIITSALAEGSGRIRRRLHHLLSQCRLASAPCLISLLDGLLQNLRRYPEDRDNLWRCAASVGRNHPIFVETCLSSLLRTHSWLSGPEPVKEDPAYLTVLLLVLNAEPSIPGMLAKFPRHVASTKIYLQELLPSLLPKTVVNDEFQNVSPLDLPNKKLCLTTDADDDGTLNGSSIMEHCSLYKFIASTICRICKLFL 567

[Close]

BLAST of Integrator complex subunit 4 vs. TrEMBL
Match: A0A4S2M744 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003470 PE=4 SV=1)

HSP 1 Score: 266.159 bits (679), Expect = 1.112e-71
Identity = 180/532 (33.83%), Postives = 273/532 (51.32%), Query Frame = 2

Query:  158 NLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQW------------------------------LDR-GFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANI-------------------QSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKD-VSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELIFE----DSDFIDEPVAKQMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVL 1588
             L S  +HVR +C+ V      P       ++   D+V W T D DARVRE AF+    W                               +R G+   N   I      GL D E  V  TS+ LV +++ +                    SD   + QS+     +AD AF  +   L   + +VRQ+A +L+S + + V+ + L++TLEK VM D+ ++++  D T    K+           K R SE   +    M+ G  +GA+I GLEDD++E+R   + T+  L+  + +FA SCQDLLVDMLTDDI+ VR ++V  L     +   + L+++Q+ I+ S L+E SG +RR +HQLL+ CRL+SA  L+ L++GLL NLR Y  DRDS+WRC+A VGR HP  V+  L+SLL+ H +L   +P+  D AY+TVLL+V+NA      +   FP H+   ++YL+ELVP L+ +     SD  D+ V    +   + D S       + L  +++D I ++ +VL
Sbjct:   52 GLRSLSAHVRAKCMDVFAGLGRP--KLWLLANQIGDLVLWHTDDSDARVRERAFDCLRIWSVYAPEEISEPKLSGSSSRSEQSQCQSSTAQERFGWMKTNLDSIYASACRGLLDAETVVRRTSLLLVARLSTLWPHYELTDPLAIGLPFPSGSSDRVALGQSSSGPILMADDAFARICVRLQDPARQVRQLAVQLLSELANSVAASCLIQTLEKMVMTDRRVRRAKSDETPLPAKV----------DKGRASEPATSSGSIMSTGP-SGAIISGLEDDYFEVRCATLATVTHLASLNTEFASSCQDLLVDMLTDDIQEVRLAAVCALG---AVGDQVPLQSEQVAIITSALAESSGRIRRRLHQLLARCRLSSAPCLVSLLDGLLHNLRRYPQDRDSLWRCAASVGRRHPAFVETCLSSLLRTHSWLSGPEPNWEDPAYLTVLLLVLNAEPGAPGMPAKFPRHISATKVYLRELVPGLLPKRTASSSDGPDDRVVPMKRLRSDSDGSCDGL---ESLCRFVLDLISRIVRVL 564

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Cavefish
Match: ints4 (integrator complex subunit 4 [Source:NCBI gene;Acc:103037017])

HSP 1 Score: 194.897 bits (494), Expect = 4.908e-51
Identity = 144/444 (32.43%), Postives = 231/444 (52.03%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFL---DPLSHFPCGSSNTF------DVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPEL 1438
            ++L+S Y  VR +CL+++G       PL+     S++T        ++  +  D D RVR  + +  +Q  +RG  L   Q         LND  ++V + ++++V  ++ +  +  V   S+  + RL D +F  +   +S  S  VR  AAKL+  ++ VS   L +TL+K +M D   K++  +R     +L+   E S+  RK       E+VDT    +   G  GA ++GLED+ YE+R+ A++ +  L+  S  FA  C D LVDM  D+IE VR  S+  L     I  ++TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+S+W+C   +G  HP LV   +  LL  HPY    +P   D AYI VL++V NA++   ++   F  H   +  YL++    LVP L
Sbjct:  159 KHLSSPYFGVRNKCLQLLGYLGTVDKPLTKESEASTSTAPLQDVQSLISDYFSDQDPRVRTASIKAMLQLHERGMKLQ--QTAYSQACKLLNDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLIDDSFGKICHMVSDGSWVVRVQAAKLLGSMQQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELYASGEFSS-GRKWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCCLAQASPSFAEKCLDFLVDMFNDEIEEVRLQSIHALR---QISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKDCIQLALLELLKNLTKYPTDRNSVWKCLKFLGLRHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAKSCPTMPALFSDHTFRHYAYLRDSLSHLVPHL 593

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Nematostella
Match: EDO33627 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRN6])

HSP 1 Score: 212.616 bits (540), Expect = 1.551e-57
Identity = 148/464 (31.90%), Postives = 236/464 (50.86%), Query Frame = 2

Query:  101 NSISSC--DDINNFQIMQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLF--------------WIDELSNFARKSRISEQVDTPEDAMAMG-GINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELI 1441
            N + SC  D  N F     +++L  ++  VR QCL++IG+     +    G+ +   +V  F  D D+RVR TA +  +   +RG  L    ++ +     L+D  +EV   ++KL+   ++I  +  VI  S+  ++RL D AF  +   ++  S +VR  A  L+  +  VS   L +TL+K VM    +K+   D     ++                W D++S        SE    PE+   M  G  GA ++GLED++ E+R+ A+  + +L+ Q+  FA+ C D LVDM  D+IE VR +++ +L     + H M LR DQLDIVLSVL + S  +R  + +LL  C L++   L   +  LL NL  Y  DR SIWRC+  +G+ H  L    +  LL  HPY    +PS  D AY+ ++++V NA+     +   FPSH   +  YL++  P+L+
Sbjct:   52 NEVMSCKSDQQNIF-----LQHLKDSHHSVRCQCLRMIGELACADTTM-GGTQSMQSLVASFAVDSDSRVRTTALQALLALHERGQKLD--MMVYEQASKALHDDYEEVRMVAIKLLWVFSHICPERTVILPSSD-EARLVDDAFIKICHMVNDMSMQVRGEAVGLLGSLHHVSPKFLEQTLDKKVMSH--LKRRKTDHEKQRDRFAGGGSSDSGWSTGRQWGDKMS--------SEGELAPEEVSLMSSGACGAFVHGLEDEYLEVRMPAVDALCELANQNPSFAMLCLDFLVDMFNDEIESVRLNAINSLR---KVCHQMELREDQLDIVLSVLEDFSHEIREGVRELLGHCHLSTRACLHSAIHALLSNLSKYPQDRASIWRCAQQLGKKHQHLASSLVPELLSTHPYFATAEPSVDDPAYVAIVILVFNATVNSPVMIPMFPSHTLRHYGYLRDSYPDLV 493

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Medaka
Match: ints4 (integrator complex subunit 4 [Source:NCBI gene;Acc:101166892])

HSP 1 Score: 187.578 bits (475), Expect = 1.237e-48
Identity = 144/469 (30.70%), Postives = 242/469 (51.60%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFL---DPL-------SHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQE----LVPELIFEDSDFIDEPVAKQMKYDDNIDA 1510
            ++L+ T+  VR +CL+++G       PL       S           ++  +  D D RVR  A +  +Q  +RG  +   Q+I +     L+D  ++V + ++++V  ++ +  +  V   S+  + RL D AF  ++  +S  S  VR  AAK +  +  VS   L +TL+K +M D   K++  +R     +LF   E S+  RK       E++DT   ++   G  GA ++GLED+ +E+R+ A++ + +L+  S  FA  C D LVDM  D+IE VR   ++++ +   I  ++TLR DQLD VL+VL + S ++R ++H+LL    +++   +   +  LLKNL  Y  DR+S+W+C   +G  HP LV   +  LL  HPY    +P   D AYI VL++V NA++   ++   F  H   +  YL++    LVP L          P  KQ+   D++D+
Sbjct:  158 KHLSDTHFGVRNKCLQLLGGLGVADAPLLKDGEGSSSSSGAVREVQTIISDYFADQDPRVRTAALKAMLQLHERGMKI--HQIIYEQACRLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDAFGKISHMVSDGSWTVRVQAAKTLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELFASGEFSS-GRKWADDAPKEKLDTNTVSLIASGACGAFVHGLEDEMFEVRIAAVEALCQLACSSPSFAEKCLDFLVDMFNDEIEEVR---LQSIHVLREISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLNKYPTDRNSVWKCLKFLGSRHPTLVLPLVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAKSCPTMPALFSDHTFRHYAYLRDSLSHLVPPLRL--------PGRKQVYSLDSVDS 609

[Close]

BLAST of Integrator complex subunit 4 vs. Ensembl Medaka
Match: ints4 (integrator complex subunit 4 [Source:NCBI gene;Acc:101166892])

HSP 1 Score: 125.561 bits (314), Expect = 5.366e-30
Identity = 97/310 (31.29%), Postives = 165/310 (53.23%), Query Frame = 2

Query:  155 RNLNSTYSHVRMQCLKVIGQFL---DPLSHFPCGSSNTFDV---VQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARK---SRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVL 1057
            ++L+ T+  VR +CL+++G       PL     GS    +V   +  +  D D RVR  A +  +Q  +RG  +   Q+I +     L+D  ++V + ++++V  ++ +  +  V   S+  + RL D AF  ++  +S  S  VR  AAK +  +  VS   L +TL+K +M D   K++  +R     +LF   E S+  RK       E++DT   ++   G  GA ++GLED+ +E+R+ A++ + +L+  S  FA  C D LVDM  D+IE VR   ++++ +   I  ++TLR DQLD VL+VL
Sbjct:  158 KHLSDTHFGVRNKCLQLLGGLGVADAPLLKDGEGSRAVREVQTIISDYFADQDPRVRTAALKAMLQLHERGMKI--HQIIYEQACRLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDAFGKISHMVSDGSWTVRVQAAKTLGSMLQVSPHFLEQTLDKKLMSDLRRKRTAHERAK---ELFASGEFSS-GRKWADDAPKEKLDTNTVSLIASGACGAFVHGLEDEMFEVRIAAVEALCQLACSSPSFAEKCLDFLVDMFNDEIEEVR---LQSIHVLREISTHITLREDQLDTVLAVL 458

[Close]

BLAST of Integrator complex subunit 4 vs. Planmine SMEST
Match: SMESG000012359.1 (SMESG000012359.1)

HSP 1 Score: 1541.94 bits (3991), Expect = 0.000e+0
Identity = 787/787 (100.00%), Postives = 787/787 (100.00%), Query Frame = 2

Query:  143 MQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELIFEDSDFIDEPVAKQMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVLFGCSFXXXXXXXXXXXXXXXXXQISALCDETRGLCLWLRDLGQLTMRTQQMPMELNRLQEGRYLAHKMIHAYTGLKLADVECLQGFIDNIDKKIKCIQEQNVIPTRETKEILSTSPPLEDLKSLPILSCIDKINSFELACLLLSNLTQVTAKQLHPTPYDTERSANKFCAGMSVSLSVRAEFYGLDATVDQHGNIDVKTPVAVVVNRPDGMSLYWQPPDHCWSAAKHNESPNXXXXXXXXXXXXXXXXXRVFFLDTDVQLSFCEWSEPGLVYLGLVILLPDKDLVWKLSEPVGVKVYPISANRTL 2503
            MQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELIFEDSDFIDEPVAKQMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVLFGCSFLSQGNSNLLRLLLQDLRQISALCDETRGLCLWLRDLGQLTMRTQQMPMELNRLQEGRYLAHKMIHAYTGLKLADVECLQGFIDNIDKKIKCIQEQNVIPTRETKEILSTSPPLEDLKSLPILSCIDKINSFELACLLLSNLTQVTAKQLHPTPYDTERSANKFCAGMSVSLSVRAEFYGLDATVDQHGNIDVKTPVAVVVNRPDGMSLYWQPPDHCWSAAKHNESPNSSSSSSGAGGGGDGGGGRVFFLDTDVQLSFCEWSEPGLVYLGLVILLPDKDLVWKLSEPVGVKVYPISANRTL
Sbjct:    1 MQVVRNLNSTYSHVRMQCLKVIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGFPLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKLKSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTVMKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGGINGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDIEVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLLSLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVNLNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKTNEIYLQELVPELIFEDSDFIDEPVAKQMKYDDNIDASHQDAVSRQDLYSYLIDTIRKLHKVLFGCSFLSQGNSNLLRLLLQDLRQISALCDETRGLCLWLRDLGQLTMRTQQMPMELNRLQEGRYLAHKMIHAYTGLKLADVECLQGFIDNIDKKIKCIQEQNVIPTRETKEILSTSPPLEDLKSLPILSCIDKINSFELACLLLSNLTQVTAKQLHPTPYDTERSANKFCAGMSVSLSVRAEFYGLDATVDQHGNIDVKTPVAVVVNRPDGMSLYWQPPDHCWSAAKHNESPNSSSSSSGAGGGGDGGGGRVFFLDTDVQLSFCEWSEPGLVYLGLVILLPDKDLVWKLSEPVGVKVYPISANRTL 787

The following BLAST results are available for this feature:

BLAST of Integrator complex subunit 4 vs. Ensembl Human
BLAST of Integrator complex subunit 4 vs. Ensembl Celegans
BLAST of Integrator complex subunit 4 vs. Ensembl Fly
BLAST of Integrator complex subunit 4 vs. Ensembl Zebrafish
BLAST of Integrator complex subunit 4 vs. Ensembl Xenopus
BLAST of Integrator complex subunit 4 vs. Ensembl Mouse
BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
BLAST of Integrator complex subunit 4 vs. TrEMBL
BLAST of Integrator complex subunit 4 vs. Ensembl Cavefish
BLAST of Integrator complex subunit 4 vs. Ensembl Sea Lamprey
BLAST of Integrator complex subunit 4 vs. Ensembl Yeast
BLAST of Integrator complex subunit 4 vs. Ensembl Nematostella
BLAST of Integrator complex subunit 4 vs. Ensembl Medaka
BLAST of Integrator complex subunit 4 vs. Planmine SMEST

BLAST of Integrator complex subunit 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2


Match Name	E-value	Identity	Description
INTS4	1.075e-52	31.72	integrator complex subunit 4 [Source:HGNC Symbol;A...	[more]
INTS4	1.747e-40	32.31	integrator complex subunit 4 [Source:HGNC Symbol;A...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
W04A4.5	5.585e-28	25.76	pep chromosome:WBcel235:I:13663462:13674997:1 gene...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
IntS4	8.076e-49	30.09	gene:FBgn0026679 transcript:FBtr0071234	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ints4	2.243e-52	31.99	integrator complex subunit 4 [Source:ZFIN;Acc:ZDB-...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cfap54	1.776e-50	31.35	cilia and flagella associated 54 [Source:Xenbase;A...	[more]
cfap54	2.402e-50	31.19	cilia and flagella associated 54 [Source:Xenbase;A...	[more]
cfap54	2.429e-50	31.35	cilia and flagella associated 54 [Source:Xenbase;A...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Ints4	9.319e-53	33.11	integrator complex subunit 4 [Source:MGI Symbol;Ac...	[more]

BLAST of Integrator complex subunit 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q96HW7\|INT4_HUMAN	5.163e-52	31.72	Integrator complex subunit 4 OS=Homo sapiens OX=96...	[more]
sp\|Q8CIM8\|INT4_MOUSE	6.519e-52	33.11	Integrator complex subunit 4 OS=Mus musculus OX=10...	[more]
sp\|Q68F70\|INT4_XENLA	1.477e-51	31.46	Integrator complex subunit 4 OS=Xenopus laevis OX=...	[more]
sp\|Q9W3E1\|INT4_DROME	8.095e-48	30.09	Integrator complex subunit 4 OS=Drosophila melanog...	[more]
sp\|Q54LH5\|INT4_DICDI	2.991e-27	32.33	Integrator complex subunit 4 homolog OS=Dictyostel...	[more]

BLAST of Integrator complex subunit 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A094ZKC6	1.723e-80	34.39	Integrator complex subunit 4 (Fragment) OS=Schisto...	[more]
A0A4Z2CRX5	2.023e-79	34.64	Integrator complex subunit 4 OS=Schistosoma japoni...	[more]
A0A5J4NDU5	4.581e-76	37.25	Integrator complex subunit 4 OS=Paragonimus wester...	[more]
G4VLH2	1.205e-74	34.09	Uncharacterized protein OS=Schistosoma mansoni OX=...	[more]
A0A4S2M744	1.112e-71	33.83	Uncharacterized protein OS=Opisthorchis felineus O...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ints4	4.908e-51	32.43	integrator complex subunit 4 [Source:NCBI gene;Acc...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Integrator complex subunit 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Integrator complex subunit 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO33627	1.551e-57	31.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Integrator complex subunit 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ints4	1.237e-48	30.70	integrator complex subunit 4 [Source:NCBI gene;Acc...	[more]
ints4	5.366e-30	31.29	integrator complex subunit 4 [Source:NCBI gene;Acc...	[more]

BLAST of Integrator complex subunit 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000012359.1	0.000e+0	100.00	SMESG000012359.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30002140 ID=SMED30002140|Name=Integrator complex subunit 4|organism=Schmidtea mediterranea sexual|type=transcript|length=2646bp
TTAAAATTTTTAAATAAATTAACAAAAATTTTTCATTACATTACTAATTT
AAATGTCTGATGTTTTACCTCCCGAAGAGTATGAAATTTTGAAGGAAATT
AATTCAATTTCTTCATGTGATGATATTAACAATTTTCAAATAATGCAAGT
GGTTCGAAATTTGAACTCTACATATTCACATGTGCGAATGCAATGTTTGA
AAGTTATTGGTCAATTTTTGGATCCACTAAGCCATTTTCCATGTGGTTCA
TCAAATACATTTGATGTGGTTCAGTGGTTTACCCAGGATCATGACGCAAG
AGTTAGAGAAACTGCATTTGAACTGTATATACAATGGTTAGATCGAGGTT
TTCCATTGCCTAATTTTCAATTAATAATTGACTTATTGGAAACTGGATTA
AATGATAGAGAGGATGAGGTAGTAAATACTTCAATGAAATTAGTGGTAAA
AATGGCCAATATTCAATCGGATTTGGAAGTTATTTCACAGTCTAATAAAC
TCAAATCTAGGTTAGCAGATAAAGCATTCTGTTGTGTTGCTTGTGCATTA
TCTCATGCGAGTTCTCGCGTTCGACAAATGGCAGCTAAACTCATGTCATG
CATTAAAGATGTTTCTGAAGCACTGTTGTTAGAAACGTTGGAAAAGACAG
TAATGAAAGATAAAATAATCAAAAAATCAGTATTCGATAGAACAAATGCA
ATCAACAAATTGTTTTGGATTGACGAATTGAGTAATTTTGCACGCAAGTC
CCGTATCAGTGAGCAAGTTGATACTCCAGAGGATGCAATGGCAATGGGCG
GCATCAATGGAGCGTTGATTTATGGATTAGAGGATGATTTCTACGAAATA
CGATTAGAGGCTATCAAAACCATTGGAAAATTGTCAATTCAATCAGAGAA
GTTTGCTGTTTCTTGTCAGGATTTACTAGTGGACATGCTAACCGATGATA
TTGAGGTCGTCCGTTCGAGTTCGGTGGAGAACCTCAGCATTGCCAGTGGA
ATCAAGCATAATATGACATTGAGGACCGACCAACTCGATATCGTTTTGAG
TGTATTATCCGAGAAAAGTGGGAACATGCGTCGATCGATCCACCAGCTCC
TCAGTTTGTGCAGACTAGCATCAGCGCATGCCTTGATGCGTTTAGTTGAA
GGCTTGTTGAAAAATTTACGAATGTATGAAATGGATCGCGATAGCATTTG
GCGATGCTCAGCGATTGTGGGCAGAAACCATCCGGAATTGGTCCAGGTCA
ATCTCAATTCTCTGTTACAAATGCATCCGTATCTCGTGTTCCAGGACCCC
TCGAAATCAGATACGGCCTACATAACAGTCCTGCTGATGGTTATCAATGC
CAGTCGCAAATTGTCCAGCATCAAAACTTGTTTTCCCAGCCATGTTAAAA
CCAATGAAATTTATCTTCAAGAACTCGTTCCAGAGCTAATATTTGAGGAT
TCCGATTTTATCGATGAGCCGGTCGCAAAGCAAATGAAATATGACGATAA
CATTGATGCGTCTCATCAAGATGCGGTGTCTCGACAAGATCTCTATTCCT
ACTTGATTGATACTATCAGAAAACTTCACAAAGTCCTATTCGGATGCAGT
TTCCTTAGCCAAGGGAACAGCAATCTATTACGGCTGCTATTGCAAGACCT
TCGACAGATCAGTGCGCTCTGTGATGAGACCCGTGGCTTGTGCTTGTGGC
TCCGTGACTTGGGTCAATTAACCATGCGCACCCAGCAAATGCCGATGGAG
TTGAATCGGCTACAAGAAGGCCGCTATTTAGCACATAAAATGATACACGC
TTACACTGGATTGAAGCTGGCTGATGTCGAATGCTTGCAAGGTTTCATTG
ACAATATCGACAAAAAGATCAAATGTATCCAGGAACAGAATGTTATCCCA
ACCAGAGAAACAAAGGAAATTCTTTCGACAAGCCCGCCTTTGGAAGATCT
AAAATCCTTGCCGATTCTCTCTTGCATTGATAAGATAAACTCATTTGAGC
TGGCTTGTTTATTGCTGTCGAATCTAACTCAAGTCACCGCTAAACAGCTT
CATCCCACTCCATACGACACAGAGAGGTCAGCGAATAAATTTTGCGCCGG
TATGAGTGTTTCTTTGTCAGTGCGGGCCGAATTTTACGGGTTAGACGCCA
CAGTTGACCAGCATGGAAATATCGATGTCAAAACCCCAGTCGCGGTTGTT
GTGAACCGCCCAGACGGGATGTCACTCTATTGGCAGCCACCTGATCACTG
TTGGAGTGCTGCAAAGCACAATGAATCTCCTAATTCTAGTAGCAGTAGTA
GTGGTGCTGGTGGCGGTGGCGACGGCGGCGGCGGTAGGGTATTCTTTCTC
GACACAGATGTCCAGTTAAGCTTCTGTGAATGGTCTGAACCGGGATTGGT
TTATTTGGGCTTAGTTATTTTGCTGCCAGATAAGGATTTAGTATGGAAAC
TTAGTGAACCTGTCGGAGTTAAAGTTTATCCGATTTCCGCTAATAGAACT
CTGTAAATATCCTTGATTTGTTTTACTGTGTATAAAAATATATAAATTTC
ATCATTCATTGCTAATTTGCGATTTTATTGGCATTTGTTTTTCATTTATA
TTAGTACTAAGTTAATATTAGTTCTGAAGTTAATGGAAATTAAGTA

protein sequence of SMED30002140-orf-1

>SMED30002140-orf-1 ID=SMED30002140-orf-1|Name=SMED30002140-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=818bp
MSDVLPPEEYEILKEINSISSCDDINNFQIMQVVRNLNSTYSHVRMQCLK
VIGQFLDPLSHFPCGSSNTFDVVQWFTQDHDARVRETAFELYIQWLDRGF
PLPNFQLIIDLLETGLNDREDEVVNTSMKLVVKMANIQSDLEVISQSNKL
KSRLADKAFCCVACALSHASSRVRQMAAKLMSCIKDVSEALLLETLEKTV
MKDKIIKKSVFDRTNAINKLFWIDELSNFARKSRISEQVDTPEDAMAMGG
INGALIYGLEDDFYEIRLEAIKTIGKLSIQSEKFAVSCQDLLVDMLTDDI
EVVRSSSVENLSIASGIKHNMTLRTDQLDIVLSVLSEKSGNMRRSIHQLL
SLCRLASAHALMRLVEGLLKNLRMYEMDRDSIWRCSAIVGRNHPELVQVN
LNSLLQMHPYLVFQDPSKSDTAYITVLLMVINASRKLSSIKTCFPSHVKT
NEIYLQELVPELIFEDSDFIDEPVAKQMKYDDNIDASHQDAVSRQDLYSY
LIDTIRKLHKVLFGCSFLSQGNSNLLRLLLQDLRQISALCDETRGLCLWL
RDLGQLTMRTQQMPMELNRLQEGRYLAHKMIHAYTGLKLADVECLQGFID
NIDKKIKCIQEQNVIPTRETKEILSTSPPLEDLKSLPILSCIDKINSFEL
ACLLLSNLTQVTAKQLHPTPYDTERSANKFCAGMSVSLSVRAEFYGLDAT
VDQHGNIDVKTPVAVVVNRPDGMSLYWQPPDHCWSAAKHNESPNSSSSSS
GAGGGGDGGGGRVFFLDTDVQLSFCEWSEPGLVYLGLVILLPDKDLVWKL
SEPVGVKVYPISANRTL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR011989	ARM-like
IPR016024	ARM-type_fold

Vocabulary: **molecular function**
Term	Definition
GO:0005488	binding
GO:0003824	catalytic activity
GO:0016831	carboxy-lyase activity
GO:0030170	pyridoxal phosphate binding

Vocabulary: **biological process**
Term	Definition
GO:0019752	carboxylic acid metabolic process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR20938	UNCHARACTERIZED	coord: 13..571
IPR016024	Armadillo-type fold	SUPERFAMILY	SSF48371	ARM repeat	coord: 23..367

Main menu

Integrator complex subunit 4

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

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