Pyruvate dehydrogenase E1 component subunit beta

Overview
NamePyruvate dehydrogenase E1 component subunit beta
Smed IDSMED30002129
Length (bp)1616
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pyruvate dehydrogenase E1 component subunit beta (SMED30002129) t-SNE clustered cells

Violin plots show distribution of expression levels for Pyruvate dehydrogenase E1 component subunit beta (SMED30002129) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pyruvate dehydrogenase E1 component subunit beta (SMED30002129) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pyruvate dehydrogenase E1 component subunit beta (SMED30002129) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002129

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30002129SMESG000068622.1 dd_Smed_v4_3374_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002129SMESG000068622.1 Contig42712uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30002129SMESG000068622.1 Contig42712newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30002129SMESG000068622.1 dd_Smed_v4_3374_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 214.542 bits (545), Expect = 3.089e-64
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT +++VS S  V  CL AA  L+K GV+CEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  178 PVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI 341
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 214.157 bits (544), Expect = 4.331e-64
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT +++VS S  V  CL AA  L+K GV+CEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  178 PVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI 341
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 214.157 bits (544), Expect = 6.003e-64
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT +++VS S  V  CL AA  L+K GV+CEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  196 PVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Match: PDHB (pyruvate dehydrogenase E1 beta subunit [Source:HGNC Symbol;Acc:HGNC:8808])

HSP 1 Score: 149.828 bits (377), Expect = 5.391e-40
Identity = 72/117 (61.54%), Postives = 90/117 (76.92%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMES 1335
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT +++VS S  V  CL AA  L+K GV+CEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME 
Sbjct:  178 PVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEG 294
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Match: BCKDHB (branched chain keto acid dehydrogenase E1 subunit beta [Source:HGNC Symbol;Acc:HGNC:987])

HSP 1 Score: 78.1814 bits (191), Expect = 7.251e-15
Identity = 52/140 (37.14%), Postives = 77/140 (55.00%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAAT-ELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPY 1401
            P IF E ++ Y  A E   EV    + IP+ +A++ + G+ V+LV++   V +    A+    K+GV CEV++LR++ P D +T+ KSVIKT  L+         G  SEI + V E    N L+AP  RV G D P P+
Sbjct:  234 PCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH 369
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Celegans
Match: pdhb-1 (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:O44451])

HSP 1 Score: 211.075 bits (536), Expect = 3.216e-63
Identity = 99/164 (60.37%), Postives = 125/164 (76.22%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG +F   DEVLS DF++PIGKAKIER G  V++VS+S  V+  L AA +L  IGV  EV+NLRSLRP D E++ +SV KTHHLV+VE GWP  GIGSEI A+VMES  F+ LDAP +RVTG D+PMPY + LE  ALP+  +++K+VKK L+I
Sbjct:  188 PVVFLENEILYGQSFPVGDEVLSDDFVVPIGKAKIERAGDHVTIVSYSRGVEFSLEAAKQLEAIGVSAEVINLRSLRPFDFESIRQSVHKTHHLVSVETGWPFAGIGSEIAAQVMESDVFDQLDAPLLRVTGVDVPMPYTQTLEAAALPTAEHVVKAVKKSLNI 351
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Celegans
Match: bckd-1B (Branched Chain Keto acid Dehydrogenase e1 (E1) subunit [Source:UniProtKB/TrEMBL;Acc:Q93619])

HSP 1 Score: 87.4261 bits (215), Expect = 1.640e-18
Identity = 57/162 (35.19%), Postives = 93/162 (57.41%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAK--IGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKK 1464
            P IF E ++ Y  A E   +V + D+ IP+G+A+  R G  ++LV++   V + L AA +LAK  +  D EV++L++++P DE+ V++SV KT  L+         G G+EI + V +    N L++P  RV G D P P+    E   LP+V+ +  ++KK
Sbjct:  208 PCIFFEPKILYRLASE---DVPTGDYTIPLGQAETVRSGKDLTLVAWGTQVHVALEAA-QLAKEKLNADVEVIDLQTIQPWDEDHVVESVQKTGRLIVTHEAPISSGFGAEIASTVQKRCFLN-LESPIDRVAGFDTPFPHVH--EPFYLPTVHRVFDAIKK 362
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Fly
Match: Pdhb (gene:FBgn0039635 transcript:FBtr0085369)

HSP 1 Score: 196.052 bits (497), Expect = 2.680e-57
Identity = 93/162 (57.41%), Postives = 115/162 (70.99%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVL 1470
            PV+FLENE+ YG AF   D V   DFL+PIGKAK+ RPG  ++LV+ S  V+  L AA ELAK G++ EV+NLRS+RPLD  T+  SV KTHHLVTVE GWP  G+G+EI AR+ME   F  LDAP  R  G D+PMPYAK LE  ALP V +++++  KVL
Sbjct:  192 PVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVL 353
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Fly
Match: Pdhb (gene:FBgn0039635 transcript:FBtr0085366)

HSP 1 Score: 196.052 bits (497), Expect = 2.680e-57
Identity = 93/162 (57.41%), Postives = 115/162 (70.99%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVL 1470
            PV+FLENE+ YG AF   D V   DFL+PIGKAK+ RPG  ++LV+ S  V+  L AA ELAK G++ EV+NLRS+RPLD  T+  SV KTHHLVTVE GWP  G+G+EI AR+ME   F  LDAP  R  G D+PMPYAK LE  ALP V +++++  KVL
Sbjct:  192 PVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVL 353
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Fly
Match: CG17691 (gene:FBgn0039993 transcript:FBtr0113761)

HSP 1 Score: 74.3294 bits (181), Expect = 5.076e-14
Identity = 54/162 (33.33%), Postives = 82/162 (50.62%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAK--IGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYA-----KPLENEALPSVNNII 1449
            P I  E +  Y  A E   EV +  +   +GKA I R G  V+L+ +   V + L  A E+AK  + +DCEV++L S+ P D  T+  S  KT  ++         G GSE LA  ++   F +L+AP  RV G D P P+       P ++  L ++N+I+
Sbjct:  206 PCIVFEPKTLYRAAVE---EVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVA-EIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSE-LASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIV 362
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Fly
Match: CG17691 (gene:FBgn0039993 transcript:FBtr0302409)

HSP 1 Score: 74.3294 bits (181), Expect = 5.076e-14
Identity = 54/162 (33.33%), Postives = 82/162 (50.62%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAK--IGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYA-----KPLENEALPSVNNII 1449
            P I  E +  Y  A E   EV +  +   +GKA I R G  V+L+ +   V + L  A E+AK  + +DCEV++L S+ P D  T+  S  KT  ++         G GSE LA  ++   F +L+AP  RV G D P P+       P ++  L ++N+I+
Sbjct:  206 PCIVFEPKTLYRAAVE---EVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVA-EIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSE-LASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIV 362
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Zebrafish
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:ZFIN;Acc:ZDB-GENE-040426-2173])

HSP 1 Score: 223.402 bits (568), Expect = 1.282e-67
Identity = 106/164 (64.63%), Postives = 131/164 (79.88%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  +EV S DF+IPIGKAKIER G  ++LVS S  V LCL AA  LAK G++CEV+NLRS+RPLD +T+  S+ KT+HLVTVEGGWP  G+G+EILAR+ME  AFNYLDAPA+RVTG DIPMPYAK LE+ ++P + +II SVKK L++
Sbjct:  196 PVVFLENELMYGVPFEMSEEVQSKDFVIPIGKAKIERQGNHITLVSHSRMVGLCLDAAAVLAKEGIECEVINLRSIRPLDADTIETSITKTNHLVTVEGGWPQFGVGAEILARIMEGPAFNYLDAPAVRVTGVDIPMPYAKILEDNSIPQIKDIIFSVKKTLNV 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 80.8777 bits (198), Expect = 6.202e-16
Identity = 52/164 (31.71%), Postives = 90/164 (54.88%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 1473
            P IF E ++ Y  A E   +V +  + IP+ +A++ + G+ ++LV++   + +    AA    K+GV CE+++L+++ P D+ETV KSV+KT  L+         G  +EI + V E    N L+AP  RV G D P P+    E   +P      ++VK++++
Sbjct:  233 PCIFFEPKILYRAAVE---QVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLN-LEAPISRVCGYDTPFPHI--FEPFYIPDKWKCFEAVKRMIN 390
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 80.4925 bits (197), Expect = 7.404e-16
Identity = 52/164 (31.71%), Postives = 90/164 (54.88%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 1473
            P IF E ++ Y  A E   +V +  + IP+ +A++ + G+ ++LV++   + +    AA    K+GV CE+++L+++ P D+ETV KSV+KT  L+         G  +EI + V E    N L+AP  RV G D P P+    E   +P      ++VK++++
Sbjct:  247 PCIFFEPKILYRAAVE---QVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLN-LEAPISRVCGYDTPFPHI--FEPFYIPDKWKCFEAVKRMIN 404
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Zebrafish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 80.4925 bits (197), Expect = 7.404e-16
Identity = 52/164 (31.71%), Postives = 90/164 (54.88%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 1473
            P IF E ++ Y  A E   +V +  + IP+ +A++ + G+ ++LV++   + +    AA    K+GV CE+++L+++ P D+ETV KSV+KT  L+         G  +EI + V E    N L+AP  RV G D P P+    E   +P      ++VK++++
Sbjct:  247 PCIFFEPKILYRAAVE---QVPTEAYYIPLSQAEVLQEGSDLTLVAWGTQIHVMREVAAMAQEKLGVSCELIDLQTILPWDKETVCKSVMKTGRLLISHEAPVTGGFAAEISSAVQEECFLN-LEAPISRVCGYDTPFPHI--FEPFYIPDKWKCFEAVKRMIN 404
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Match: bag6 (BCL2 associated athanogene 6 [Source:Xenbase;Acc:XB-GENE-478689])

HSP 1 Score: 215.698 bits (548), Expect = 6.734e-65
Identity = 101/164 (61.59%), Postives = 129/164 (78.66%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  ++  S D++IPIGKAKIERPG+ ++LVS S +V  CL AA  LAK GVDCEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+GSEI A++ME  AFNYLDAP +RVTG D+PMPYAK LE   +P V +II +VKK L++
Sbjct:  166 PVVFLENELMYGVPFELSEQAQSKDYVIPIGKAKIERPGSQITLVSHSRSVGHCLEAANVLAKEGVDCEVINMRTIRPMDIETIETSVVKTNHLVTVEGGWPQFGVGSEICAKIMEGPAFNYLDAPVVRVTGTDVPMPYAKILEENCVPQVKDIIFAVKKTLNL 329
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Match: bag6 (BCL2 associated athanogene 6 [Source:Xenbase;Acc:XB-GENE-478689])

HSP 1 Score: 215.698 bits (548), Expect = 7.682e-65
Identity = 101/164 (61.59%), Postives = 129/164 (78.66%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  ++  S D++IPIGKAKIERPG+ ++LVS S +V  CL AA  LAK GVDCEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+GSEI A++ME  AFNYLDAP +RVTG D+PMPYAK LE   +P V +II +VKK L++
Sbjct:  175 PVVFLENELMYGVPFELSEQAQSKDYVIPIGKAKIERPGSQITLVSHSRSVGHCLEAANVLAKEGVDCEVINMRTIRPMDIETIETSVVKTNHLVTVEGGWPQFGVGSEICAKIMEGPAFNYLDAPVVRVTGTDVPMPYAKILEENCVPQVKDIIFAVKKTLNL 338
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Match: bag6 (BCL2 associated athanogene 6 [Source:Xenbase;Acc:XB-GENE-478689])

HSP 1 Score: 215.698 bits (548), Expect = 8.261e-65
Identity = 101/164 (61.59%), Postives = 129/164 (78.66%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  ++  S D++IPIGKAKIERPG+ ++LVS S +V  CL AA  LAK GVDCEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+GSEI A++ME  AFNYLDAP +RVTG D+PMPYAK LE   +P V +II +VKK L++
Sbjct:  172 PVVFLENELMYGVPFELSEQAQSKDYVIPIGKAKIERPGSQITLVSHSRSVGHCLEAANVLAKEGVDCEVINMRTIRPMDIETIETSVVKTNHLVTVEGGWPQFGVGSEICAKIMEGPAFNYLDAPVVRVTGTDVPMPYAKILEENCVPQVKDIIFAVKKTLNL 335
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Match: bag6 (BCL2 associated athanogene 6 [Source:Xenbase;Acc:XB-GENE-478689])

HSP 1 Score: 216.083 bits (549), Expect = 1.012e-64
Identity = 101/164 (61.59%), Postives = 129/164 (78.66%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  ++  S D++IPIGKAKIERPG+ ++LVS S +V  CL AA  LAK GVDCEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+GSEI A++ME  AFNYLDAP +RVTG D+PMPYAK LE   +P V +II +VKK L++
Sbjct:  196 PVVFLENELMYGVPFELSEQAQSKDYVIPIGKAKIERPGSQITLVSHSRSVGHCLEAANVLAKEGVDCEVINMRTIRPMDIETIETSVVKTNHLVTVEGGWPQFGVGSEICAKIMEGPAFNYLDAPVVRVTGTDVPMPYAKILEENCVPQVKDIIFAVKKTLNL 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Match: bag6 (BCL2 associated athanogene 6 [Source:Xenbase;Acc:XB-GENE-478689])

HSP 1 Score: 215.698 bits (548), Expect = 1.213e-64
Identity = 101/164 (61.59%), Postives = 129/164 (78.66%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG  FE  ++  S D++IPIGKAKIERPG+ ++LVS S +V  CL AA  LAK GVDCEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+GSEI A++ME  AFNYLDAP +RVTG D+PMPYAK LE   +P V +II +VKK L++
Sbjct:  190 PVVFLENELMYGVPFELSEQAQSKDYVIPIGKAKIERPGSQITLVSHSRSVGHCLEAANVLAKEGVDCEVINMRTIRPMDIETIETSVVKTNHLVTVEGGWPQFGVGSEICAKIMEGPAFNYLDAPVVRVTGTDVPMPYAKILEENCVPQVKDIIFAVKKTLNL 353
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Mouse
Match: Pdhb (pyruvate dehydrogenase (lipoamide) beta [Source:MGI Symbol;Acc:MGI:1915513])

HSP 1 Score: 214.927 bits (546), Expect = 2.307e-64
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG AFE P E  S DFLIPIGKAKIER GT +++V+ S  V  CL AA  L+K G++CEV+NLR++RP+D E +  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II +VKK L+I
Sbjct:  196 PVVMLENELMYGVAFELPAEAQSKDFLIPIGKAKIERQGTHITVVAHSRPVGHCLEAAAVLSKEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKVLEDNSVPQVKDIIFAVKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 79.7221 bits (195), Expect = 7.907e-16
Identity = 52/140 (37.14%), Postives = 77/140 (55.00%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPY 1401
            P IF E ++ Y  A E   +V    + IP+ +A++ + G+ V+LV++   V +    A+    K+GV CEV++LR++ P D +TV KSVIKT  L+         G  SEI + V E    N L+AP  RV G D P P+
Sbjct:  164 PCIFFEPKILYRAAVE---QVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH 299
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 79.7221 bits (195), Expect = 7.907e-16
Identity = 52/140 (37.14%), Postives = 77/140 (55.00%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPY 1401
            P IF E ++ Y  A E   +V    + IP+ +A++ + G+ V+LV++   V +    A+    K+GV CEV++LR++ P D +TV KSVIKT  L+         G  SEI + V E    N L+AP  RV G D P P+
Sbjct:  164 PCIFFEPKILYRAAVE---QVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH 299
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Mouse
Match: Bckdhb (branched chain ketoacid dehydrogenase E1, beta polypeptide [Source:MGI Symbol;Acc:MGI:88137])

HSP 1 Score: 79.337 bits (194), Expect = 2.025e-15
Identity = 52/140 (37.14%), Postives = 77/140 (55.00%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCL-TAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPY 1401
            P IF E ++ Y  A E   +V    + IP+ +A++ + G+ V+LV++   V +    A+    K+GV CEV++LR++ P D +TV KSVIKT  L+         G  SEI + V E    N L+AP  RV G D P P+
Sbjct:  232 PCIFFEPKILYRAAVE---QVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH 367
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Match: sp|P11966|ODPB_BOVIN (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Bos taurus OX=9913 GN=PDHB PE=1 SV=2)

HSP 1 Score: 216.468 bits (550), Expect = 4.223e-64
Identity = 103/164 (62.80%), Postives = 131/164 (79.88%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT V++V+ S  V  CL AAT L+K G++CEV+NLR++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  196 PVVVLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHVTIVAHSRPVGHCLEAATVLSKEGIECEVINLRTIRPMDIETIEGSVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Match: sp|P26269|ODPB_ASCSU (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Ascaris suum OX=6253 PE=1 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 1.519e-63
Identity = 101/165 (61.21%), Postives = 124/165 (75.15%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PVI LENE+ YG  F    E  SPDF++P G+AKI+RPG  +++VS S  VD+ L AA ELAK G+DCEV+NLR +RPLD +TV  SVIKT HLVTVE GWP CG+G+EI ARV ES AF YLD P +RVTG D+PMPYA+PLE  ALP   +++K VKK L++Q
Sbjct:  197 PVICLENEILYGMKFPVSPEAQSPDFVLPFGQAKIQRPGKDITIVSLSIGVDVSLHAADELAKSGIDCEVINLRCVRPLDFQTVKDSVIKTKHLVTVESGWPNCGVGAEISARVTESDAFGYLDGPILRVTGVDVPMPYAQPLETAALPQPADVVKMVKKCLNVQ 361
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Match: sp|Q9D051|ODPB_MOUSE (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Mus musculus OX=10090 GN=Pdhb PE=1 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 1.614e-63
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG AFE P E  S DFLIPIGKAKIER GT +++V+ S  V  CL AA  L+K G++CEV+NLR++RP+D E +  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II +VKK L+I
Sbjct:  196 PVVMLENELMYGVAFELPAEAQSKDFLIPIGKAKIERQGTHITVVAHSRPVGHCLEAAAVLSKEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKVLEDNSVPQVKDIIFAVKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Match: sp|P49432|ODPB_RAT (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Rattus norvegicus OX=10116 GN=Pdhb PE=1 SV=2)

HSP 1 Score: 214.542 bits (545), Expect = 2.014e-63
Identity = 101/164 (61.59%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG AFE P E  S DFLIPIGKAKIER GT +++V+ S  V  CL AA  L+K G++CEV+NLR++RP+D E +  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  196 PVVMLENELMYGVAFELPTEAQSKDFLIPIGKAKIERQGTHITVVAHSRPVGHCLEAAAVLSKEGIECEVINLRTIRPMDIEAIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Match: sp|Q5RE79|ODPB_PONAB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Pongo abelii OX=9601 GN=PDHB PE=2 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 2.410e-63
Identity = 102/164 (62.20%), Postives = 130/164 (79.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG  FE P E  S DFLIPIGKAKIER GT +++VS S  V  CL AA  L+K GV+CEV+N+R++RP+D ET+  SV+KT+HLVTVEGGWP  G+G+EI AR+ME  AFN+LDAPA+RVTGAD+PMPYAK LE+ ++P V +II ++KK L+I
Sbjct:  196 PVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLNI 359
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Match: A0A2T7NTB3 (Pyruvate dehydrogenase E1 component subunit beta OS=Pomacea canaliculata OX=400727 GN=C0Q70_14902 PE=4 SV=1)

HSP 1 Score: 243.432 bits (620), Expect = 2.416e-71
Identity = 115/164 (70.12%), Postives = 136/164 (82.93%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YGH FE PDE LS DF+IP GKAKIER G+ ++LV+ S  V  CL AA ELA  G++CEVVNLRSLRPLDEET++KSV+KT+HLVTVEGGWP CGIG+E+ ARVMES+AFNYLDAP +RVTGAD+PMPYAK LE  ALP V NII +VKK L++
Sbjct:  246 PVVCLENEILYGHTFEIPDEALSKDFVIPFGKAKIEREGSHITLVAHSIAVGKCLDAAKELAGKGIECEVVNLRSLRPLDEETIIKSVVKTNHLVTVEGGWPQCGIGAEVCARVMESAAFNYLDAPVLRVTGADVPMPYAKSLEERALPQVFNIITAVKKSLNL 409
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Match: A0A0B7AZ95 (Pyruvate dehydrogenase E1 component subunit beta (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF146931 PE=4 SV=1)

HSP 1 Score: 239.965 bits (611), Expect = 1.544e-70
Identity = 110/164 (67.07%), Postives = 135/164 (82.32%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG +F+  DEVLS DFL+PIGK KIER G  ++LVS S  V LCL AA  LA  G++CEV+NLR+LRPLD+ET+ KSV+KTHHLVTVEGGWP CGIG++I+ARVMES A+NYLDAP +RVTGAD+PMPYAK LE  A+P + NI+ +VKK LH+
Sbjct:  207 PVVFLENELMYGISFDVADEVLSKDFLVPIGKCKIEREGNHITLVSHSKPVGLCLEAANVLAGKGIECEVINLRTLRPLDDETIFKSVMKTHHLVTVEGGWPQCGIGADIVARVMESQAYNYLDAPILRVTGADVPMPYAKSLEELAMPGIKNIVTAVKKCLHL 370
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Match: A0A1S3JAV1 (Pyruvate dehydrogenase E1 component subunit beta OS=Lingula unguis OX=7574 GN=LOC106171636 PE=4 SV=1)

HSP 1 Score: 238.81 bits (608), Expect = 3.718e-70
Identity = 111/165 (67.27%), Postives = 136/165 (82.42%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PV+FLENE+ YG  FE  DE++S DFLIP+GKAKIER GT+V+LVS S  V  CL AA EL ++G+  EV+NLR+LRP+DEE+++KSV+KT+HLVTVEGGWP CGIG+EI AR+ ES AFNYLDAP  RVTGADIPMPYAK +E  ALP V NI+ SVKKV+++Q
Sbjct:  197 PVVFLENEIMYGVGFEVTDEIMSKDFLIPLGKAKIEREGTNVTLVSHSRFVGHCLDAAKELEQLGISAEVINLRTLRPMDEESIIKSVMKTNHLVTVEGGWPQCGIGAEICARIFESPAFNYLDAPVARVTGADIPMPYAKTMEQYALPQVFNIVNSVKKVMNVQ 361
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Match: A0A1S3JBG2 (Pyruvate dehydrogenase E1 component subunit beta OS=Lingula unguis OX=7574 GN=LOC106171636 PE=4 SV=1)

HSP 1 Score: 238.81 bits (608), Expect = 4.368e-70
Identity = 111/165 (67.27%), Postives = 136/165 (82.42%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PV+FLENE+ YG  FE  DE++S DFLIP+GKAKIER GT+V+LVS S  V  CL AA EL ++G+  EV+NLR+LRP+DEE+++KSV+KT+HLVTVEGGWP CGIG+EI AR+ ES AFNYLDAP  RVTGADIPMPYAK +E  ALP V NI+ SVKKV+++Q
Sbjct:  204 PVVFLENEIMYGVGFEVTDEIMSKDFLIPLGKAKIEREGTNVTLVSHSRFVGHCLDAAKELEQLGISAEVINLRTLRPMDEESIIKSVMKTNHLVTVEGGWPQCGIGAEICARIFESPAFNYLDAPVARVTGADIPMPYAKTMEQYALPQVFNIVNSVKKVMNVQ 368
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Match: A0A5J4P4G3 (Pyruvate dehydrogenase E1 component subunit beta OS=Paragonimus westermani OX=34504 GN=DEA37_0013845 PE=4 SV=1)

HSP 1 Score: 238.81 bits (608), Expect = 4.372e-70
Identity = 110/165 (66.67%), Postives = 133/165 (80.61%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PV++LENEV YGH F+  DE +S DFL+PIGKAKIER GT V+LV +S  V + L AA ELAK+GV+ EV+NLRSLRPLDEETV  SV KTHHLVTVEG WP CGIG+EI ARVMES  F+YLDAPA RVTGAD+PMPYAK LE   +P  +N++++VK +L+I+
Sbjct:  200 PVVYLENEVLYGHTFDVSDEAMSSDFLLPIGKAKIEREGTDVTLVGYSMAVGVSLAAAEELAKLGVNAEVINLRSLRPLDEETVFNSVKKTHHLVTVEGAWPTCGIGAEICARVMESDTFHYLDAPAFRVTGADVPMPYAKKLEQACIPEAHNVVRTVKMMLNIK 364
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Cavefish
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:ZFIN;Acc:ZDB-GENE-040426-2173])

HSP 1 Score: 212.231 bits (539), Expect = 1.209e-63
Identity = 102/164 (62.20%), Postives = 127/164 (77.44%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG A E  +E  S DF+IPIGKAK+ER G  ++LVS S  V  CL AA  LAK G++CEV+NLR++RPLD ET+  SV+KT+HL+TVEGGWP  G+G+EI AR+ME  AFNYLDAPA RVTG DIPMPYAK LE+ + P + +II SVKK L++
Sbjct:  185 PVVFLENELMYGVACEMSEEAQSKDFIIPIGKAKVERQGGHITLVSHSRMVGHCLDAAAVLAKEGIECEVINLRTIRPLDVETIEASVMKTNHLITVEGGWPQFGVGAEICARIMEGPAFNYLDAPATRVTGVDIPMPYAKILEDNSTPQIKDIIFSVKKTLNV 348
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Cavefish
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:ZFIN;Acc:ZDB-GENE-030124-2])

HSP 1 Score: 80.4925 bits (197), Expect = 6.112e-16
Identity = 53/164 (32.32%), Postives = 89/164 (54.27%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAAT-ELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 1473
            P IF E ++ Y  A E   +V +  + +P+ +A++ + G+ V+LV++   V +    AT    K+GV CEV++L+++ P D ETV KSV+KT  L+         G  +EI + + E    N L+AP  RV G D P P+    E   +P      ++VK++++
Sbjct:  239 PCIFFEPKILYRAAVE---QVPTEPYHLPLSQAEVVQEGSDVTLVAWGTQVHVMREVATMAQEKLGVSCEVIDLQTILPWDIETVCKSVVKTGRLLISHEAPVTGGFAAEISSSIQEQCFLN-LEAPIARVCGYDTPFPHI--FEPFYIPDKWKCFEAVKRMIN 396
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Yeast
Match: PDB1 (E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; PDH is an evolutionarily conserved multi-protein complex found in mitochondria [Source:SGD;Acc:S000000425])

HSP 1 Score: 192.586 bits (488), Expect = 8.937e-57
Identity = 95/166 (57.23%), Postives = 125/166 (75.30%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAK-IGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PV+FLENE+ YG +FE  +E LSP+F +P  KAKIER GT +S+V+++ NV   L AA  L K  GV  EV+NLRS+RPLD E ++K+V KT+HL+TVE  +P  G+G+EI+A+VMES AF+YLDAP  RVTGAD+P PYAK LE+ A P    I+K+VK+VL I+
Sbjct:  202 PVVFLENELLYGESFEISEEALSPEFTLPY-KAKIEREGTDISIVTYTRNVQFSLEAAEILQKKYGVSAEVINLRSIRPLDTEAIIKTVKKTNHLITVESTFPSFGVGAEIVAQVMESEAFDYLDAPIQRVTGADVPTPYAKELEDFAFPDTPTIVKAVKEVLSIE 366
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Nematostella
Match: EDO40608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6S9])

HSP 1 Score: 218.009 bits (554), Expect = 5.430e-66
Identity = 103/164 (62.80%), Postives = 128/164 (78.05%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+ LENE+ YG +FE  DE +S DFL+PIGKAKIERPG+ ++LV+ S  V+ CL AA +L   G+D EV+NLRS+RP+D + ++ SV KT+HLVTVEGGWP  G+G+EI A VMES AF++LDAP IRVTGADIPMPYA  LE  ALP V NI+ SVKK L+I
Sbjct:  200 PVVVLENELMYGTSFEMSDEAMSADFLVPIGKAKIERPGSHITLVAHSRPVETCLQAAKQLESEGIDVEVLNLRSIRPMDTQAIVDSVKKTNHLVTVEGGWPHFGVGAEIAATVMESEAFDFLDAPIIRVTGADIPMPYAALLEKNALPQVENIVNSVKKTLNI 363
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Nematostella
Match: EDO29237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T476])

HSP 1 Score: 64.3142 bits (155), Expect = 2.146e-11
Identity = 49/162 (30.25%), Postives = 76/162 (46.91%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVL 1470
            PV+F E ++ Y  A E   +V   D+ +P+ +A++   G  +SLV                        +++LR++ P D++TV +SV KT  L+         G G EI A  ++   F  L+AP  RV G D P P+   LE   LP      ++VKKV+
Sbjct:  164 PVVFFEPKILYRQAVE---DVPVKDYSLPLSEAEVLEKGFDLSLVG----------------------RLIDLRTILPWDKDTVCQSVEKTGRLLIAHEACHTGGFGGEI-ASTVQDRCFLSLEAPIQRVCGWDTPFPHI--LEPFYLPDKWRCFEAVKKVI 297
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 214.542 bits (545), Expect = 1.088e-64
Identity = 104/164 (63.41%), Postives = 127/164 (77.44%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG +FE  +E  S DF IPIG+AK+ER G+ V+LVS S  V  CL AA  LAK G++CEV+NLR++RP+D E++  SV+KT+HLVTVEGGWP  G+G+EI ARVME  AFNYLDAP  RVTG DIPMPYAK LE  +LP V +II SVKK L+I
Sbjct:  163 PVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLAKEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTLNI 326
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 215.312 bits (547), Expect = 1.452e-64
Identity = 104/164 (63.41%), Postives = 127/164 (77.44%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG +FE  +E  S DF IPIG+AK+ER G+ V+LVS S  V  CL AA  LAK G++CEV+NLR++RP+D E++  SV+KT+HLVTVEGGWP  G+G+EI ARVME  AFNYLDAP  RVTG DIPMPYAK LE  +LP V +II SVKK L+I
Sbjct:  197 PVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLAKEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTLNI 360
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Medaka
Match: pdhb (pyruvate dehydrogenase E1 beta subunit [Source:NCBI gene;Acc:100049362])

HSP 1 Score: 214.542 bits (545), Expect = 2.781e-64
Identity = 104/164 (63.41%), Postives = 127/164 (77.44%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHI 1476
            PV+FLENE+ YG +FE  +E  S DF IPIG+AK+ER G+ V+LVS S  V  CL AA  LAK G++CEV+NLR++RP+D E++  SV+KT+HLVTVEGGWP  G+G+EI ARVME  AFNYLDAP  RVTG DIPMPYAK LE  +LP V +II SVKK L+I
Sbjct:  206 PVVFLENELMYGVSFEMTEESQSKDFTIPIGEAKVERQGSHVTLVSHSRYVGHCLDAAAVLAKEGIECEVINLRTIRPMDVESIEASVMKTNHLVTVEGGWPQFGVGAEICARVMEGPAFNYLDAPVTRVTGVDIPMPYAKTLEEHSLPQVKDIIFSVKKTLNI 369
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Medaka
Match: bckdhb (branched chain keto acid dehydrogenase E1 subunit beta [Source:NCBI gene;Acc:101170333])

HSP 1 Score: 80.1073 bits (196), Expect = 7.671e-16
Identity = 54/165 (32.73%), Postives = 91/165 (55.15%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELA--KIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLH 1473
            P IF E ++ Y  A E   +V    + IP+ +A+I + G+ V+LV++   + + L   +++A  K+GV CEV++L+++ P D ETV KSV+KT  L+         G  +EI + V E    N L+AP  RV G D P P+    E   +P      +++K++++
Sbjct:  231 PCIFFEPKILYRAAVE---QVPVESYTIPLSEAEILQEGSDVTLVAWGTQIHV-LREVSDMAQEKLGVSCEVIDLKTILPWDVETVCKSVVKTGRLLVSHEAPVTGGFAAEISSTVQEECFLN-LEAPISRVCGYDTPFPHI--FEPFYIPDKWKCFEAIKRMIN 388
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Planmine SMEST
Match: SMESG000068622.1 (SMESG000068622.1)

HSP 1 Score: 337.035 bits (863), Expect = 9.237e-112
Identity = 164/165 (99.39%), Postives = 164/165 (99.39%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMES AFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ
Sbjct:  197 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESPAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 361
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Planmine SMEST
Match: SMESG000068622.1 (SMESG000068622.1)

HSP 1 Score: 336.265 bits (861), Expect = 1.483e-111
Identity = 164/165 (99.39%), Postives = 164/165 (99.39%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 1479
            PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMES AFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ
Sbjct:  193 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESPAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ 357
[Close]
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Planmine SMEST
Match: SMESG000043691.1 (SMESG000043691.1)

HSP 1 Score: 84.3445 bits (207), Expect = 2.112e-17
Identity = 61/163 (37.42%), Postives = 84/163 (51.53%), Query Frame = 1 
Query:  985 PVIFLENEVFYGHAFETPDEVLSPDFLIPIGKAKIERPGTSVSLVSFSGNVD-LCLTAATELAKIGVDCEVVNLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFNYLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVL 1470
            P IF E ++ Y  A E   +V    +  P+ KA I   G  V+++ +   V  L   A   L K  V CEV++L++L P DE+ V +SV KT  LV         G G+EI A V E+  FN L+AP  RVTG D P PY    E   LP +   +++VK V+
Sbjct:  206 PCIFFEPKILYRGAVE---DVPIKFYKEPLSKADIVMEGKDVTMIGWGTQVHVLKEVAKLSLTKFDVSCEVIDLQTLSPWDEDLVYESVKKTGRLVISHEAPLTSGFGAEIAASVQEACFFN-LEAPIQRVTGFDTPFPYI--YEPFYLPDIWRCLEAVKTVI 362
The following BLAST results are available for this feature:
BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PDHB3.089e-6462.20pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
PDHB4.331e-6462.20pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
PDHB6.003e-6462.20pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
PDHB5.391e-4061.54pyruvate dehydrogenase E1 beta subunit [Source:HGN... [more]
BCKDHB7.251e-1537.14branched chain keto acid dehydrogenase E1 subunit ... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pdhb-13.216e-6360.37Pyruvate dehydrogenase E1 component subunit beta, ... [more]
bckd-1B1.640e-1835.19Branched Chain Keto acid Dehydrogenase e1 (E1) sub... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Pdhb2.680e-5757.41gene:FBgn0039635 transcript:FBtr0085369[more]
Pdhb2.680e-5757.41gene:FBgn0039635 transcript:FBtr0085366[more]
CG176915.076e-1433.33gene:FBgn0039993 transcript:FBtr0113761[more]
CG176915.076e-1433.33gene:FBgn0039993 transcript:FBtr0302409[more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pdhb1.282e-6764.63pyruvate dehydrogenase E1 beta subunit [Source:ZFI... [more]
bckdhb6.202e-1631.71branched chain keto acid dehydrogenase E1 subunit ... [more]
bckdhb7.404e-1631.71branched chain keto acid dehydrogenase E1 subunit ... [more]
bckdhb7.404e-1631.71branched chain keto acid dehydrogenase E1 subunit ... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bag66.734e-6561.59BCL2 associated athanogene 6 [Source:Xenbase;Acc:X... [more]
bag67.682e-6561.59BCL2 associated athanogene 6 [Source:Xenbase;Acc:X... [more]
bag68.261e-6561.59BCL2 associated athanogene 6 [Source:Xenbase;Acc:X... [more]
bag61.012e-6461.59BCL2 associated athanogene 6 [Source:Xenbase;Acc:X... [more]
bag61.213e-6461.59BCL2 associated athanogene 6 [Source:Xenbase;Acc:X... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Pdhb2.307e-6462.20pyruvate dehydrogenase (lipoamide) beta [Source:MG... [more]
Bckdhb7.907e-1637.14branched chain ketoacid dehydrogenase E1, beta pol... [more]
Bckdhb7.907e-1637.14branched chain ketoacid dehydrogenase E1, beta pol... [more]
Bckdhb2.025e-1537.14branched chain ketoacid dehydrogenase E1, beta pol... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P11966|ODPB_BOVIN4.223e-6462.80Pyruvate dehydrogenase E1 component subunit beta, ... [more]
sp|P26269|ODPB_ASCSU1.519e-6361.21Pyruvate dehydrogenase E1 component subunit beta, ... [more]
sp|Q9D051|ODPB_MOUSE1.614e-6362.20Pyruvate dehydrogenase E1 component subunit beta, ... [more]
sp|P49432|ODPB_RAT2.014e-6361.59Pyruvate dehydrogenase E1 component subunit beta, ... [more]
sp|Q5RE79|ODPB_PONAB2.410e-6362.20Pyruvate dehydrogenase E1 component subunit beta, ... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T7NTB32.416e-7170.12Pyruvate dehydrogenase E1 component subunit beta O... [more]
A0A0B7AZ951.544e-7067.07Pyruvate dehydrogenase E1 component subunit beta (... [more]
A0A1S3JAV13.718e-7067.27Pyruvate dehydrogenase E1 component subunit beta O... [more]
A0A1S3JBG24.368e-7067.27Pyruvate dehydrogenase E1 component subunit beta O... [more]
A0A5J4P4G34.372e-7066.67Pyruvate dehydrogenase E1 component subunit beta O... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pdhb1.209e-6362.20pyruvate dehydrogenase E1 beta subunit [Source:ZFI... [more]
bckdhb6.112e-1632.32branched chain keto acid dehydrogenase E1 subunit ... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PDB18.937e-5757.23E1 beta subunit of the pyruvate dehydrogenase (PDH... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO406085.430e-6662.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO292372.146e-1130.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pdhb1.088e-6463.41pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
pdhb1.452e-6463.41pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
pdhb2.781e-6463.41pyruvate dehydrogenase E1 beta subunit [Source:NCB... [more]
bckdhb7.671e-1632.73branched chain keto acid dehydrogenase E1 subunit ... [more]
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BLAST of Pyruvate dehydrogenase E1 component subunit beta vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000068622.19.237e-11299.39SMESG000068622.1[more]
SMESG000068622.11.483e-11199.39SMESG000068622.1[more]
SMESG000043691.12.112e-1737.42SMESG000043691.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002129 ID=SMED30002129|Name=Pyruvate dehydrogenase E1 component subunit beta|organism=Schmidtea mediterranea sexual|type=transcript|length=1616bp
TAATCGGTAAAAATGATTTGTGACTTTTCTTTTTCTCGTTGATTATTTTT
CGTTTTCTTGTTTGCGATTTTCAAAATTCTAATACTTGTTTGACTAATGA
GATAATATATTAGCAATATAAATTACAGGAAAAATTGCTGGGAAAAATTT
CTTTCATCTATTTTCAGAGTTACAACAAATGGGATATATAATCCGGTTGG
TATTTTATAGTGGTATTATCTGTGCTATCACCGCATAAGTTAATGAATGA
TTGGCAAAAGCTCAAACTCATTAGTAAAAACTGTATTATGAAAATATAAG
GGAATAGAAAACATAAAAGAAGGAAATGTATTTTAATTAATTATGACACG
GAGGGAAACACTATTGGCAAAGAAACACTTTGCAGGCAAAACAAATGAAT
TTTGGTTATTTTAATTAAAGTAAACTTTATCACAACCACGACGCTACTGA
CGCAAAAAAACTTACGAATTTGTTGACGCACTAGGCTGTAAAGGAATTCT
GAAATGTTCGGTACTTTTTAATCTGGTTGTGCGTCCTATTGTCCAAATGG
AAATCAAAAGATTAGGAAAAAAACTTCTATGCTCACAATTAACCCAGGAT
TTGCATAATTCAATTATACATCCTTGGAAGAAAAAATATTAAAGTACAAC
AAGTTCAAGATATGATTTAGCATTTGAAATTGCTGAGACTGAAGCTGCTT
CCGAGGCATTATGTTTAAGGAAAGGAATAGAAATGATGATAGTAAGAAAT
ATGAATTTACAATTTTTGCTGCACTTACATATGACCAGTTATTTAAATTT
GAGGTGAAGAAATATTCATAGAGTTGAGAGGGATTTATATATTTCCTAAA
AGCCTTCTGGTGAAGTCTTTGAGAAAGTTACAATCATAGTTTTTAACATG
TCAAAATTAGAAAAAAGGTTCAACTGTGTCGCACTATATATTATTATATA
TCTTAGTATTTTTGTGTTGAATTTCATTTCTTTTCCAGTTATTTTCTTAG
AAAATGAAGTTTTCTACGGGCATGCTTTTGAAACCCCAGATGAGGTTTTG
TCTCCAGATTTTCTCATTCCCATCGGCAAAGCCAAAATTGAAAGGCCAGG
AACTAGTGTGTCTTTAGTTTCCTTTTCTGGAAATGTAGATTTATGTCTCA
CAGCTGCTACTGAATTAGCAAAAATCGGTGTTGATTGTGAAGTTGTAAAT
TTACGGTCCCTTCGACCTCTTGACGAGGAAACTGTCATGAAATCAGTAAT
AAAAACACATCATTTAGTTACTGTTGAAGGCGGTTGGCCGGTATGCGGAA
TTGGATCTGAAATTCTCGCACGAGTCATGGAATCATCAGCGTTTAATTAT
TTGGATGCGCCAGCGATACGGGTAACCGGAGCTGATATTCCGATGCCTTA
TGCGAAGCCATTAGAAAACGAAGCTTTACCTAGCGTTAATAACATTATTA
AATCTGTGAAAAAAGTTCTGCACATTCAATAGTTATAATTATATTTAGAT
TGCAAAATATTTATTGTCGCTTTTCTTAGTAGACTTTTATTTGTTTTGAG
ATGATAACTAATGCTAATTCTATAAAATTTAAATTTTTTTTAATTGTTTC
AATTGTTTGGCTTAGT
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protein sequence of SMED30002129-orf-1

>SMED30002129-orf-1 ID=SMED30002129-orf-1|Name=SMED30002129-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=195bp
MSKLEKRFNCVALYIIIYLSIFVLNFISFPVIFLENEVFYGHAFETPDEV
LSPDFLIPIGKAKIERPGTSVSLVSFSGNVDLCLTAATELAKIGVDCEVV
NLRSLRPLDEETVMKSVIKTHHLVTVEGGWPVCGIGSEILARVMESSAFN
YLDAPAIRVTGADIPMPYAKPLENEALPSVNNIIKSVKKVLHIQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR027110PDHB
IPR029061THDP-binding
IPR033248Transketolase_C
IPR009014Transketo_C/PFOR_II
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
GO:0005975carbohydrate metabolic process
GO:0006006glucose metabolic process
GO:0006086acetyl-CoA biosynthetic process from pyruvate
GO:0006099tricarboxylic acid cycle
GO:0055114oxidation-reduction process
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0004738pyruvate dehydrogenase activity
GO:0004739pyruvate dehydrogenase (acetyl-transferring) activity
GO:0016491oxidoreductase activity
GO:0034604pyruvate dehydrogenase (NAD+) activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005739mitochondrion
GO:0005759mitochondrial matrix
GO:0045254pyruvate dehydrogenase complex
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009014Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IIGENE3DG3DSA:3.40.50.920coord: 1..80
e-value: 2.9E-20
score: 74.4
IPR009014Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain IISUPERFAMILYSSF52922TK C-terminal domain-likecoord: 2..79
IPR033248Transketolase, C-terminal domainPFAMPF02780Transketolase_Ccoord: 2..70
e-value: 9.2E-17
score: 61.1
IPR027110Pyruvate dehydrogenase E1 component subunit betaPANTHERPTHR11624DEHYDROGENASE RELATEDcoord: 2..80
NoneNo IPR availablePANTHERPTHR11624:SF56PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIALcoord: 2..80