SUMO-activating enzyme subunit

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDL--SQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV 1608
            +A   VLVVGAGGIGCELLKNLV+  F  I +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K  R  P  LD + +    ++   S   +    G+KDQ+   ++++ + F  S   L   +++  D A L+WDKDD  AMDFV +AAN+RM +F  + M +RF+IKSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ D+C  + ++   + R K++       P  +CYVC+ K E+T+   + + +++  L+  I++    M+AP+V I++    I+   ++   E    K L +F + NG+  +  DFLQ+Y  ++ I    +L  D  +E++GD 
Sbjct:   15 VAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRK--RKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFS-MNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRL-NVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDA 550          

Query:  271 MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDL--SQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV 1608
            M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K  R  P  LD + +    ++   S   +    G+KDQ+   ++++ + F  S   L   +++  D A L+WDKDD  AMDFV +AAN+RM +F  + M +RF+IKSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ D+C  + ++   + R K++       P  +CYVC+ K E+T+   + + +++  L+  I++    M+AP+V I++    I+   ++   E    K L +F + NG+  +  DFLQ+Y  ++ I    +L  D  +E++GD 
Sbjct:    1 MNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRK--RKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFS-MNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRL-NVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDA 454          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD 819
            + +A   VLVVGAGGIGCELLKNLV+  F  I                             L AKESVL+F P  NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K  R  P  LD
Sbjct:   13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHID----------------------------LVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRK--RKPPVPLD 255          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVPDQNDPE 624
            VLV+GAGG+GCELLKNL +  F++I VID+DTIDVSNLNRQFLFR +++G+ KA  A E +    PN N+    + +    +N  F++ F I++  LD+  AR ++N M +             S +PLI+GGT G++G  +VIL G TAC EC  +  P Q  +P CTI + P  P HC+ + + L     Q FGE      V  D +DPE
Sbjct:   58 VLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI--QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGE-----GVPLDGDDPE 262          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVPDQNDPE 624
            VLV+GAGG+GCELLKNL +  F++I VID+DTIDVSNLNRQFLFR +++G+ KA  A E +    PN N+    + +    +N  F++ F I++  LD+  AR ++N M +             S +PLI+GGT G++G  +VIL G TAC EC  +  P Q  +P CTI + P  P HC+ + + L     Q FGE      V  D +DPE
Sbjct:   72 VLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI--QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGE-----GVPLDGDDPE 276          

Query:   13 RMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQK-QYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQN--DPELTNETT----ENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVK---------DQEKFSLRNWCQAFKNSANQLSERM-SQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELK-NDYEI 1596
            + + I +S +LV+GAGGIGCELLKNL +  F+++ VIDLDTID+SNLNRQFLFRKE+V  SKA TA + V +F P + +   HD +   KYN +FF+ +DIVLNALDN+AARNYVNRMC  +N PLI+ G+ GY GQV VI++GKT CYEC  KP Q+  YP CTIRNTPSE IHC VWAK +FNQLFGE D D DV PD +  DP+ T   T    +   + +P  +  R  W  S  YD+  +   LF  +I  L  M+ LW + +R  P              L    ++ TGG           D   ++L    + F     +L E++ ++ D  L +DKD  + M FVAA ANIR  +F I PM ++F+IK+MAGNIIPAIA+TNA++AGI V  A +++ G    C   + +   + RG+I        P   C+VCS+K E+ +   + + +++  L   +L+  L MLAP+V     S +I+  D D  D     K L +  + +G +  C DF Q  E  L IK    L  +D+E+
Sbjct:    7 KHEKIVQSKILVIGAGGIGCELLKNLAVTGFRKVHVIDLDTIDISNLNRQFLFRKEHVSSSKAATATQVVKQFCPQIELTFDHDSIFEKKYNMEFFQAYDIVLNALDNRAARNYVNRMCHAANRPLIDSGSGGYFGQVSVIMRGKTECYECVDKPVQQTTYPGCTIRNTPSEHIHCTVWAKHVFNQLFGEVDIDDDVSPDMDAVDPDNTEAVTTEKEKEAMKEEPAPVGTR-QWAESVDYDAAKVFDKLFLHDIEYLCKMEHLWKQRKRPSP--------------LEFHTASSTGGEPQSLCDAQRDDTSIWTLSTCAKVFSTCIQELLEQIRAEPDVKLAFDKDHAIIMSFVAACANIRAKIFGI-PMKSQFDIKAMAGNIIPAIASTNAIVAGIIVTEAVRVIEGSTVICNSSIATTQSNPRGRIFGGDATNPPNPRCFVCSEKREVFIYV-NPDTMTVGGLCEKVLKQKLNMLAPDVMDSATSRIIVSSDGDTDD--LLPKKLAEVSIEDGAILSCDDFQQEMEIKLFIKKGDRLAGDDFEV 533          

Query:   43 LVVGAGGIGCELLKNLVMWNFK-----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
             VVGAG IGCELLKNL M          I + D+D I++SNLNRQFLFR+ +VG  K+  A  +V  FN +V I+A+ + V     + +N +FF   + V NALDN  AR Y++R C+   +PL+E GTMG +G  QV+    T  Y     P +K+ P CT++N P+E  H + WA+  F   F +P
Sbjct:  521 FVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAARAVTAFNSDVRIEALAERVGLETEHIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNFPNEIQHTIQWAREQFETFFAQP 708          

Query:   10 SRMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVL 321
            S M N+  ++VL+ G G +G E+ KNL++   + +T+ D      S+L+ Q+  R  +VG ++A +  E + + N +VN++     V +++   +F KTFD+V+
Sbjct:  118 SAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLAKWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQ-----VSTDELTEEFVKTFDLVV 216          

Query:   43 LVVGAGGIGCELLKNLVMWNFK-----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
             VVGAG IGCELLKNL M          I + D+D I++SNLNRQFLFR+ +VG  K+  A  +V  FN +V I+A+ + V     + +N +FF   + V NALDN  AR Y++R C+   +PL+E GTMG +G  QV+    T  Y     P +K+ P CT++N P+E  H + WA+  F   F +P
Sbjct:  521 FVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAARAVTAFNSDVRIEALAERVGLETEHIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNFPNEIQHTIQWAREQFETFFAQP 708          

Query:   10 SRMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVL 321
            S M N+  ++VL+ G G +G E+ KNL++   + +T+ D      S+L+ Q+  R  +VG ++A +  E + + N +VN++     V +++   +F KTFD+V+
Sbjct:  118 SAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLAKWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQ-----VSTDELTEEFVKTFDLVV 216          

Query:   43 LVVGAGGIGCELLKNLVMWNFK-----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
             VVGAG IGCELLKNL M          I + D+D I++SNLNRQFLFR+ +VG  K+  A  +V  FN +V I+A+ + V     + +N +FF   + V NALDN  AR Y++R C+   +PL+E GTMG +G  QV+    T  Y     P +K+ P CT++N P+E  H + WA+  F   F +P
Sbjct:  520 FVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAARAVTAFNSDVRIEALAERVGLETEHIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNFPNEIQHTIQWAREQFETFFAQP 707          

Query:   10 SRMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVL 321
            S M N+  ++VL+ G G +G E+ KNL++   + +T+ D      S+L+ Q+  R  +VG ++A +  E + + N +VN++     V +++   +F KTFD+V+
Sbjct:  117 SAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLAKWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQ-----VSTDELTEEFVKTFDLVV 215          

Query:   43 LVVGAGGIGCELLKNLVMWNFK-----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
             VVGAG IGCELLKNL M          I + D+D I++SNLNRQFLFR+ +VG  K+  A  +V  FN +V I+A+ + V     + +N +FF   + V NALDN  AR Y++R C+   +PL+E GTMG +G  QV+    T  Y     P +K+ P CT++N P+E  H + WA+  F   F +P
Sbjct:  436 FVVGAGAIGCELLKNLSMMGVACGEGGLIKITDMDQIEISNLNRQFLFRRRDVGGKKSECAARAVTAFNSDVRIEALAERVGLETEHIFNDEFFGELNGVANALDNVDARRYMDRRCVYYRLPLLESGTMGTKGNTQVVYPYLTESYSSSVDPPEKEIPVCTLKNFPNEIQHTIQWAREQFETFFAQP 623          

Query:   10 SRMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVL 321
            S M N+  ++VL+ G G +G E+ KNL++   + +T+ D      S+L+ Q+  R  +VG ++A +  E + + N +VN++     V +++   +F KTFD+V+
Sbjct:   33 SAMVNLRTASVLISGLGSVGVEIAKNLILGGVRHVTIHDTKLAKWSDLSAQYYLRDADVGHNRATSCYERLAELNDSVNVQ-----VSTDELTEEFVKTFDLVV 131          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP--------------------------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEK-----FSLRNWCQAFKNSANQLSERM--SQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGK-IVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIK-VDSEL-KNDYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRK 1734
            + KS VLVVGAGGIGCE+LKNLV+  F +I +IDLDTID+SNLNRQFLF +E+VGKSKA  A+ES L FNP+  I A HD V S  Y  +FFK FD+VL+ALDN+AARN+VNRMCL +++PLIE GT GY GQV++I +G T CYEC PK  Q+ +P CTIRNTPSEPIHC+VWAK LFNQLFGE   D+D+ PD  DP+   +   +G+  +P                          +++N R  W     YD+  L    FN++I  LL M  LW            K+ + V  D L       +G  KD  K     +S+    Q F NS  +LS      + D  L WDKDD  AMDFVAA AN+R  +F I    +RFEIKSMAGNIIPAIATTNA+ AGISV+ A+K+L  + ++C  V      + R   +V       P  +C+VC+    +TL    T  + +K L+  +L   L ML P+V +Q+  S+ +   ++   E    K L + ++ +G + +C DF QNYE  + I   D+E  +N +E++ D   +      D D+   +    +  DE        TN  GD K
Sbjct:   17 VKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLEDEDISPDAADPDAKEKDGGDGN-GEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTR-QWAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTR---------KAPVPVQWDTL--LPEGSSGDQKDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDI-ERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASDPAITLKI-DTKRMRIKELRDEVLVKTLNMLNPDVTVQSNGSI-LISSEEGETECNDGKLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQL---KPKDEDQKEAVK---DKEDEPKSAKKRSTNGEGDSK 600          

Query:   28 AKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNI----KAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL-------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFL 558
             K  VL++GAGG+GCELLK+L +  F  + VID+DTI++SNLNRQFLFR+ ++G SKA  A   +    P   +    K I D      ++  F++ F +V+  LD+  AR ++N M L              S +P+I+GGT G++G  +VIL G TAC EC     P Q  YP CTI NTP  P HC+ + K +
Sbjct:   47 TKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQD------FDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIEYVKII 236          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFK----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNK---YNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLF 573
            + +A S   +VGAG IGCELLKN  M        +I V D+D I+ SNLNRQFLFR  +V K K++TA +++ + NP VN+ A    V +     ++ DFF   D V NALDN  AR Y++R C+ + IPL+E GT+G  G VQVI+   T  Y     P +K  P CT++N P+   H + WA+  F  +F
Sbjct:  600 EKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGVF 791          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFK----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNK---YNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLF 573
            + +A S   +VGAG IGCELLKN  M        +I V D+D I+ SNLNRQFLFR  +V K K++TA +++ + NP VN+ A    V +     ++ DFF   D V NALDN  AR Y++R C+ + IPL+E GT+G  G VQVI+   T  Y     P +K  P CT++N P+   H + WA+  F  +F
Sbjct:  417 EKLADSKWFIVGAGAIGCELLKNFGMLGLGTGNGQIFVTDMDLIEKSNLNRQFLFRPHDVQKPKSMTAADAIKRMNPEVNVTAYELRVGAETEKVFSEDFFGKLDGVANALDNVDARIYMDRKCIFNRIPLVETGTLGTLGNVQVIVPFATESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGVF 608          

Query:   34 SNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYEC-YPKP 477
            S+VL+VG GG+GC   + L       + ++D D ++ SN +RQ L  ++  G SKA +A+ ++L+ NP+  I+  H  ++         + +D+VL+  DN   R  ++  C+  + PL+ G  +   GQ+ V       CY C +P P
Sbjct:   92 SSVLIVGLGGLGCPAAQYLAAAGCGHLGLVDYDEVERSNFHRQILHSEDRCGMSKAESARIALLELNPHCEIQC-HSRMLYPHNAMHIIRGYDVVLDCTDNVPTRYLLSDACVMLSKPLVSGSALKMDGQLTVYNYANGPCYRCIFPVP 239          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE------LTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSD----RNGNLNSPPNSVDETADL---------------NDSGTNVSGDRKRKHEDS 1752
            D+++   VLVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG+T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE               DQ   +K      W  S  YD   L   LF D+I  LL+M  LW K  R  P  L+   IN     L      +  G+KDQ+   ++ + Q F++S   L  ++ +  D A LVWDKDD  AMDFV AA+N+RM+VF  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A KILN   ++C  + ++   + R K++       P   CYVC+ K E+T+   + +   ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL+ D  +E++GD      +  +  +     NGN +S   S    A +               + +    S +RKRKH D+
Sbjct:   14 DSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKLFKDDIMYLLTMDKLWKK--RKAPLPLEWEEIN----QLGSQEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKL-NVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDAPDKAPAPSAPEEGKNIANGNKDSAQPSTSSKAAVEDDDVLLVDSDEEPSSSTMDTESSNRKRKHHDA 612          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE------LTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLL----------KILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSD----RNGNLNSPPNSVDETADL---------------NDSGTNVSGDRKRKHEDS 1752
            D+++   VLVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG+T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE               DQ   +K      W  S  YD   L             LF D+I  LL+M  LW K  R  P  L+   IN     L      +  G+KDQ+   ++ + Q F++S   L  ++ +  D A LVWDKDD  AMDFV AA+N+RM+VF  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A KILN   ++C  + ++   + R K++       P   CYVC+ K E+T+   + +   ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL+ D  +E++GD      +  +  +     NGN +S   S    A +               + +    S +RKRKH D+
Sbjct:   14 DSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKK--RKAPLPLEWEEIN----QLGSQEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKL-NVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDAPDKAPAPSAPEEGKNIANGNKDSAQPSTSSKAAVEDDDVLLVDSDEEPSSSTMDTESSNRKRKHHDA 622          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE------LTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLL----------KILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSD----RNGNLNSPPNSVDETADL---------------NDSGTNVSGDRKRKHEDS 1752
            D+++   VLVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG+T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE               DQ   +K      W  S  YD   L             LF D+I  LL+M  LW K  R  P  L+   IN     L      +  G+KDQ+   ++ + Q F++S   L  ++ +  D A LVWDKDD  AMDFV AA+N+RM+VF  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A KILN   ++C  + ++   + R K++       P   CYVC+ K E+T+   + +   ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL+ D  +E++GD      +  +  +     NGN +S   S    A +               + +    S +RKRKH D+
Sbjct:   14 DSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKK--RKAPLPLEWEEIN----QLGSQEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKL-NVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDAPDKAPAPSAPEEGKNIANGNKDSAQPSTSSKAAVEDDDVLLVDSDEEPSSSTMDTESSNRKRKHHDA 622          

Query:  490 YPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE------LTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLL----------KILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTG-GVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEI 1560
            +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE               DQ   +K      W  S  YD   L             LF D+I  LL+M  LW K  R  P  L+   IN     L+     V G G+KDQ+   ++ + Q F++S   L  ++ +  D A LVWDKDD  AMDFV AA+N+RM+VF  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A KILN   ++C  + ++   + R K++       P   CYVC+ K E+T+   + +   ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +
Sbjct:    2 FPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKK--RKAPLPLEWEEIN----QLAGSQEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKL-NVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNV 369          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNI----KAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLK+L +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + V    P  ++    K I D       +  F++ F IV+  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HCV + + L     + FG+      VV D +DP+
Sbjct:   71 ILVIGAGGLGCELLKDLALSGFRHIHVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFVNDRVPGCSVVPHFKKIQD------LDETFYRQFHIVVCGLDSVIARRWMNGMLLSLLIYEDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCVEYVRMLLWPKEKPFGD-----GVVLDGDDPK 275          

Query:  121 IDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP-VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTA--LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDV 1608
            IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FFK F +V+NALDN AARN+VNRMCL + IPLIE GT GY GQV V+ KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE  +    N    D  +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N  I    Q    +  G+KDQ+   + +  Q F  S   L E++ +      LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T        + L + KV +     +ML   V    ++  II     ++      + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV
Sbjct:   28 IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAASAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPVPLEWSSLHNKGILHALQI---IVTGLKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVT--------VKLNVHKVTV-----QMLQDKV----RTGEIISSALLQLTTANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDV 506          

Query:  121 IDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTA--LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDV 1608
            IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FFK F +V+NALDN AARN+VNRMCL + IPLIE GT GY GQV V+ KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +    +Q  S++  G+KDQ+   + +  Q F  S   L E++ +      LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T        + L + KV +     +ML   V    ++  II     ++      + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV
Sbjct:   23 IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTQAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPVPLEWSSLHNKENCSETQNESSLQ-GLKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVT--------VKLNVHKVTV-----QMLQDKV----RTGEIISSALLQLTTANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDV 508          

Query:   94 MWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTA--LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDV 1608
            +W   EI +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FFK F +V+NALDN AARN+VNRMCL + IPLIE GT GY GQV V+ KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +    +Q  S++  G+KDQ+   + +  Q F  S   L E++ +      LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T        + L + KV +     +ML   V    ++  II     ++      + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV
Sbjct:   27 LW---EIVLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTQAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPVPLEWSSLHNKENCSETQNESSLQ-GLKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVT--------VKLNVHKVTV-----QMLQDKV----RTGEIISSALLQLTTANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDV 518          

Query:  121 IDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTA--LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDV 1608
            IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FFK F +V+NALDN AARN+VNRMCL + IPLIE GT GY GQV V+ KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +I             +KDQ+   + +  Q F  S   L E++ +      LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T        + L + KV +     +ML   V    ++  II     ++      + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV
Sbjct:   34 IDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTQAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPVPLEWSSLHNKEIGSC----------LKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVT--------VKLNVHKVTV-----QMLQDKV----RTGEIISSALLQLTTANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDV 510          

Query:  109 EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFN-----QLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTA--LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDV 1608
            EI +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FFK F +V+NALDN AARN+VNRMCL + IPLIE GT GY GQV V+ KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LF      QLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +    +Q  S++  G+KDQ+   + +  Q F  S   L E++ +      LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T        + L + KV +     +ML   V    ++  II     ++      + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV
Sbjct:   29 EIVLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFKSIVWLQLFGEEDADQEVAPDIADPEAAWDPTQAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPVPLEWSSLHNKENCSETQNESSLQ-GLKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVT--------VKLNVHKVTV-----QMLQDKV----RTGEIISSALLQLTTANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDV 523          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKP----EVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV-EHVISSAVSDSDR---NGNLNSPPNSVDETADLND------------SGTNVSGD---RKRKHED 1749
            ++   VLVVGAGGIGCELLKNLV+  F  I +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F+P  NI+A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K +   P    EV  +   N D  +  Q       G+KDQ+   ++++   F  S   L   +++  D A L+WDKDD  AMDFV +AAN+RM +F  + M +RF+IKSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ D+C  + ++   + R K++       P  +CYVC+ K E+T+   + + +++  L+  I++    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ I    +L  D  +E++GD  E V      D+ +   NG+ +    S     + +D            + T+ SGD   RKRK E+
Sbjct:   15 VSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEANADQQNEPQL------GLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFS-MNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRL-NVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDSPEKVGPKQAEDAAKSIANGSDDGAQPSTSTAQEQDDVLIVDSDEEGPSNSTDCSGDDKARKRKLEE 614          

Query:  244 NIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            NI+A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE
Sbjct:    2 NIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPE 128          

Query:  352 YVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE 645
            +VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE
Sbjct:    1 HVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTE 98          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVP-DQNDPE 624
            VLV+GAGG+GCELLKNL +  F++I VID+DTIDVSNLNRQFLFR ++VG+ KA  A E +    PN N+    + +    +N  F++ F I++  LD+  AR ++N M +             S +PLI+GGT G++G  +VIL G TAC EC  +  P Q  +P CTI + P  P HC+ + + L     Q FG      D VP D +DPE
Sbjct:   58 VLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKI--QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFG------DGVPLDGDDPE 262          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVP-DQNDPE 624
            VLV+GAGG+GCELLKNL +  F++I VID+DTIDVSNLNRQFLFR ++VG+ KA  A E +    PN N+    + +    +N  F++ F I++  LD+  AR ++N M +             S +PLI+GGT G++G  +VIL G TAC EC  +  P Q  +P CTI + P  P HC+ + + L     Q FG      D VP D +DPE
Sbjct:   72 VLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKI--QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFG------DGVPLDGDDPE 276          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKP----EVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV-EHVISSAVSDSDR---NGNLNSPPNSVDETADLND------------SGTNVSGD---RKRKHED 1749
            ++   VLVVGAGGIGCELLKNLV+  F  I +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F+P  NI+A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K +   P    EV  +   N D  +  Q       G+KDQ+   ++++   F  S   L   +++  D A L+WDKDD  AMDFV +AAN+RM +F  + M +RF+IKSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ D+C  + ++   + R K++       P  +CYVC+ K E+T+   + + +++  L+  I++    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ I    +L  D  +E++GD  E V      D+ +   NG+ +    S     + +D            + T+ SGD   RKRK E+
Sbjct:   15 VSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEANADQQNEPQL------GLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFS-MNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRL-NVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDSPEKVGPKQAEDAAKSIANGSDDGAQPSTSTAQEQDDVLIVDSDEEGPSNSTDCSGDDKARKRKLEE 614          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE------LTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLL----------KILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSD----RNGNLNSPPNSVDETADL---------------NDSGTNVSGDRKRKHEDS 1752
            D+++   VLVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG+T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE               DQ   +K      W  S  YD   L             LF D+I  LL+M  LW K  R  P  L+   IN     L      +  G+KDQ+   ++ + Q F++S   L  ++ +  D A LVWDKDD  AMDFV AA+N+RM+VF  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A KILN   ++C  + ++   + R K++       P   CYVC+ K E+T+   + +   ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL+ D  +E++GD      +  +  +     NGN +S   S    A +               + +    S +RKRKH D+
Sbjct:   14 DSLSSCRVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRNFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGQTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPADAAARATASDQDGDIKRVSTKEWARSTGYDPIKLFNKVSALSQTSPYLFKDDIMYLLTMDKLWKK--RKAPLPLEWEEIN----QLGSQEQVIGSGLKDQQVLGVQGYAQLFQHSVETLRSQLKEKGDGAELVWDKDDPPAMDFVTAASNLRMNVFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKILNSDFEQCRTIFLNKQPNPRKKLLVPCALDPPNASCYVCASKPEVTVKL-NVHKTMVQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNNKFLSDFGIRNGSRLQADDFLQDYTLLVNVIHSEELEKDVEFEVVGDAPDKAPAPSAPEEGKNIANGNKDSAQPSTSSKAAVEDDDVLLVDSDEEPSSSTMDTESSNRKRKHHDA 622          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTE-------NGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDL--SQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV 1608
            +A   VLVVGAGGIGCELLKNLV+  F  I +IDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P  NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV  I KG T CYEC+PKP Q+ +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD+ DPE   E TE       + +  D  +++ +  W  S  YD   L   LF D+IR LL+M  LW K  R  P  LD + +    ++   S   +    G+KDQ+   ++++ + F  S   L   +++  D A L+WDKDD  AMDFV +AAN+RM +F  + M +RF+IKSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ D+C  + ++   + R K++       P  +CYVC+ K E+T+   + + +++  L+  I++    M+AP+V I++    I+   ++   E    K L +F + NG+  +  DFLQ+Y  ++ I    +L  D  +E++GD 
Sbjct:   15 VAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTK-EWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRK--RKPPVPLDWAEVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAELIWDKDDPSAMDFVTSAANLRMHIFS-MNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNPNCYVCASKPEVTVRL-NVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNHKKLSEFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDA 550          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSM 1755
            ++ S +LVVGAGGIGCELLKNLV+  F  + VIDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P+ NI A HD +M+  YN +FFK F + +NALDN AARN+VNRMCL + IPLIE GT GY GQV VI KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +     Q  S++  G+KDQ+  ++ ++ Q F  S   L E++ +  D A LVWDKDDV AMDFV AAAN+RM +F  + M ++F++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T+   + + +++++L+  IL+    M+AP+V I++    I+   +    +    + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV              G    P  SV    + +D G   S  + +  +D +
Sbjct:   15 VSASRLLVVGAGGIGCELLKNLVLTGFTNLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDANITAYHDSIMNPDYNVEFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTKAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPIPLEWASLHNKENCSEIQNESSLL-GLKDQKVLNVASYAQLFSKSVETLREQLREKGDGAELVWDKDDVPAMDFVTAAANLRMHIFS-MNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKL-NVHKVTVQMLQDKILKEKFAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEFGIRNSSQLQADDFLQDYTLMMNILHSDEMEKDVDFEVVGDVPE-----------KGPQKPPEESVKNITNGSDDGAQPSTSKAQDQDDVL 586          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ-SDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKN--DYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSM 1755
            ++ S +LVVGAGGIGCELLKNLV+  F  + VIDLDTIDVSNLNRQFLF+K++VG+SKA  AKESVL+F P+ +I A HD +M+  YN +FFK F + +NALDN AARN+VNRMCL + IPLIE GT GY GQV VI KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE   + T+  ++ +       +K      W  S  YD   L   LF D+I+ LL+M  LW K  R  P  L+  SL N +     Q  S++  G+KDQ+  ++ ++ Q F  S   L E++ +  D A LVWDKDDV AMDFV AAAN+RM +F  + M ++F++KSMAGNIIPAIATTNA+I+G+ VL   KIL+G  ++C  V ++   + R K++       P   CYVC+ K E+T+   + + +++++L+  IL+    M+AP+V I++    I+   +    +    + + +F + N +  +  DFLQ+Y  ++ I    E++   D+E++GDV              G    P  SV    + +D G   S  + +  +D +
Sbjct:   15 VSASRLLVVGAGGIGCELLKNLVLTGFTNLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDASITAYHDSIMNPDYNVEFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTKAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRK--RKPPIPLEWASLHNKENCSEIQNESSLL-GLKDQKVLNVASYAQLFSKSVETLREQLREKGDGAELVWDKDDVPAMDFVTAAANLRMHIFS-MNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKL-NVHKVTVQMLQDKILKEKFAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEFGIRNSSQLQADDFLQDYTLMMNILHSDEMEKDVDFEVVGDVPE-----------KGPQKPPEESVKNITNGSDDGAQPSTSKAQDQDDVL 586          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENG-------DQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERM-SQSDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEF-VLEIKVDS-ELKNDYEILGDVEHVISSAVSDSDRNGNLNSPPNS------------VDETADLNDSGTNVSGD--RKRKHEDSMEHELKHK 1776
            + +  SN+LVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLFRKE+VG+SKA  AKESVL FNPNV+I A HD VMS  Y+ +FFK F +V+NALDNKAARN+VNRMCL +++PL+E G+ GY GQV VI KG+T CYEC PKP QK +P CTIRNTPSEPIHCVVWAK LFNQLFGE D DQDV PD  DPELT E  +         D+   +      AW     Y+   L    F D+I+ LLSMK LW K  RV P  LD S +  + D     M++ +G ++DQ+ + ++     F      L + + +Q D   LVWDKDD V+MDFV + ANIR  +F I PM TRF+IKSMAGNIIPAIATTNA+IAG+ ++ A+KIL  +   C ++ ++   + R +++      SP   CYVC+ K E+T++  +T    +  L+  +L++HL M+AP+V I +    I+   ++   E   +K L  F V +GT  +C DFLQ Y   ++   V+  E + D+E++GD+   +         NG       +            +D   DL +    + G   RKRK +D +E   K +
Sbjct:   15 EQVKNSNILVVGAGGIGCELLKNLVLTGFKTIEVIDLDTIDVSNLNRQFLFRKEHVGRSKAQVAKESVLNFNPNVSITAYHDSVMSPDYDVNFFKKFTLVMNALDNKAARNHVNRMCLAADVPLVESGSAGYLGQVTVIKKGQTECYECRPKPVQKTFPGCTIRNTPSEPIHCVVWAKHLFNQLFGELDPDQDVSPDTEDPELTAEAGQTALLSEAKIDEIGGLHRKSTRAWAQEVGYNPEKLFNKFFRDDIKYLLSMKTLWKK--RVPPTPLDMSGLPENPD-----MTSNSGVLRDQKLWGIKECADVFAECLESLKKDLATQGDGGVLVWDKDDTVSMDFVTSVANIRAYIFGI-PMKTRFQIKSMAGNIIPAIATTNAVIAGLIIMEAFKILGNRLHSCKEIYLNRVPNDRNRLLIPCCLNSPNPKCYVCAPKPEVTVVLNTTTF-KVGALQDKVLKSHLGMVAPDVEIDDMKGTILISSEEGETEENNDKFLSDFGVRSGTRLKCDDFLQVYSLNIIVAHVEKLEGEKDFEVVGDLSE-LQPQQEKQKTNGQQELADKALAAANDEDDLMIIDSIDDLQEQSLEMKGHLLRKRKVDDEVEESPKRR 615          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDPVKLNIR----LAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQL-SERMSQSDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKNDYE--ILGDVEHV 1617
            +N++   VLVVGAGGIGCELLKNLV+  F +I VIDLDTIDVSNLNRQFLFRKE+VGKSK+  AKES LKFNPNVNI A HD VM+  Y ADFFK F +V+NALDN+AARN+VNRMCL +++PL+E GT GY GQV VI KG T CYEC PK AQK +P CTIRNTPSEPIHCVVWAK LFNQLFGE D DQDV PD  DPELT    E+  + +     I       W +   YD+  +   LF D+I+ LL+M+ LW K  R  PE L       D ++LS    + T  ++DQ  +S++     F     +L ++  +Q D   LVWDKDD  A+DFV +AAN+R ++F I    +RF+IKSMAGNIIPAIATTNA+IAG+ V+ A KIL+ + DKC  V ++   + R K++ + +   P   CYVCS K E+T++  +T  I++K L+  IL++ L M+AP+V I N    II   ++   E   +K L +F++ NG+  +C DFLQNY   + I    +L+++ E  ++GD+  +
Sbjct:   11 NNVSNCKVLVVGAGGIGCELLKNLVLTGFSDIQVIDLDTIDVSNLNRQFLFRKEHVGKSKSQVAKESALKFNPNVNIVAYHDSVMNPDYGADFFKQFKLVMNALDNRAARNHVNRMCLAADVPLVESGTAGYLGQVTVIKKGLTECYECRPKAAQKTFPGCTIRNTPSEPIHCVVWAKHLFNQLFGEEDPDQDVSPDTEDPELTAAAGESALEKETEGKEIERKSTRVWAMDTGYDAEKIFSKLFRDDIKYLLTMETLWKK--RRPPEPL-------DYNNLSDESPSSTNDMRDQRIWSMKECADVFSKCLAKLKTDLAAQGDGGMLVWDKDDDKALDFVVSAANVRANIFGI-SQKSRFDIKSMAGNIIPAIATTNAIIAGLIVMEALKILDNKFDKCTAVYLNRKPNFRKKLLDAGRLDPPNPKCYVCSAKPEVTVVL-NTQKITIKFLEDKILKSELGMVAPDVEIDNGLGTIIISSEEGETEQNNDKFLSKFNIINGSRLKCDDFLQNYNLNITIAHVEKLEDEKEFMVVGDMAEL 540          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPEL------TNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSER---MSQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV 1608
            +  S VLVVGAGGIGCELLKNLV+  F++I VIDLDTIDVSNLNRQFLFRK +VGKSKAL AKES  K NP+  IKA HD V+  +Y  +FFK F IVLNALDN+ AR++VNRMCL +N+ LIE GT GY GQV  I+K  T CYEC PKPAQK YP CTIRNTPSEPIHC+VWAK LFNQLFGE DAD+DV PD +DPEL       N   E+GD     +++ RL W VS  YD   L   LFN++I  LL M  LW K  R  P  L  +L+    D +    ++   G  DQ  +S+      F+ S   L  R   +S  D+ L WDKD    +DFV A AN+R   F I P  +RF++KSMAGNIIPAIATTNA+IAG+ VL A+KIL G+ + C  V ++   + R K++   Q + P   CY CS K E+ +   +T  ++L++L+  IL+ HL M AP+V + +    I+   ++   E   EK L   +V +GT  RC DFLQN++ V+ I     L +D  +E++G+V
Sbjct:   10 VKSSKVLVVGAGGIGCELLKNLVLAGFQDIEVIDLDTIDVSNLNRQFLFRKAHVGKSKALVAKESAEKINPDAKIKAHHDSVIKPEYGLEFFKRFSIVLNALDNRGARSHVNRMCLAANVTLIESGTAGYLGQVTPIIKNVTECYECQPKPAQKTYPGCTIRNTPSEPIHCIVWAKHLFNQLFGEADADEDVSPDSSDPELIGQVNSQNMVQESGDGGSLHRVSTRL-WAVSCGYDPVKLFNKLFNEDISYLLRMDKLWKK--RTPPTSLKWNLLP---DAVPSSSNDSVAGTNDQRLWSIAECGIIFRESLRSLKTRIQSLSPGDS-LTWDKDSKDCLDFVTACANLRAHCFGI-PQKSRFDVKSMAGNIIPAIATTNAIIAGVIVLQAFKILQGKKESCSAVYLNKQPNLRKKMIVPTQLVKPSPKCYACSSKAEVFVYL-NTKQVTLQVLEDKILKEHLHMCAPDVEVDDGKGTILISSEEGETEGNREKCLAHLNVTHGTRLRCDDFLQNFQLVMNILHKDSLTDDKEFEVVGNV 539          

Query:   22 NIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNET-------TENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQ--SDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSD--SDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSME 1758
            N+    +LVVGAGGIGCELLKNLV+  F +I VIDLDTIDVSNLNRQFLFRKE+VGKSKA  AKES L FNPN  I A HD +MS  Y  DFFK F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG T CYEC PKP QK +P CTIRNTPSEPIHCVVWAK LFNQLFGE D DQDV PD  DPELT E         E  +    ++      W +   YD+  +   LF D+I+ LLSM+ LW K  R  P  LD  +L + +  + S  M       +DQ  +S++   Q F +    L +  +    +  LVWDKDD +AMDFVA+ +NIR  +F I    T+F+IKSMAGNIIPAIATTNA+IA + V+   K+L+G+ ++C  + ++   + R K++       P   CYVCS K E+T++  +T  +++K L+  IL++ L M+AP+V I +    I+   ++   E   +K L +F V NG++ +C DFLQ+YE  + I    +L+ D  ++++GD+  + +  + +  +++NG+  S     D+   +++     SG +++  ++  E
Sbjct:   15 NVLSCKLLVVGAGGIGCELLKNLVLTGFHDIVVIDLDTIDVSNLNRQFLFRKEHVGKSKAQVAKESALNFNPNAKITAYHDSIMSPDYGVDFFKKFTMVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGLTECYECQPKPPQKSFPGCTIRNTPSEPIHCVVWAKHLFNQLFGEEDPDQDVSPDTEDPELTAEAGQTALEQKEQSNVAGGIERKSTRTWAMETGYDAKKIFNKLFRDDIKYLLSMETLWKK--RRPPNPLDFDNLPHTECSEPSTVM-------RDQRVWSMKECAQVFSDCLAGLKKEFTNQGENGMLVWDKDDELAMDFVASTSNIRSHIFGI-NQKTKFDIKSMAGNIIPAIATTNAIIAAVIVMEGLKVLDGRIEECKQIYLNRQPNPRKKLLVPCALDKPSPKCYVCSSKPEVTVVL-NTEKMTIKTLEDKILKSALGMVAPDVEIDDGKGTILISSEEGEMEENNDKFLSEFHVGNGSILKCDDFLQSYELKIIIAHKDKLEEDKEFDVVGDLSELHAKPLVEQPTNQNGSTTSHQEEEDDLMIVDEVEVIKSGTKRKADQEPDE 596          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDP-------VKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLD-KSLINVDIDDLSQFMSNVTGG-------VKDQEKFSLRNWCQAFKNSANQL-SERMSQSDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEF-VLEIKVDS-ELKNDYEILGDVEHV 1617
            + +  S +LVVGAGGIGCELLKNLV+  FK+I VIDLDTIDVSNLNRQFLFRKE+VGKSKA  A+ES LKFNP+  IKA HD VMS +Y+ +FFK FD+VLNALDN+AARN+VNRMCL ++ PL+E GT GY GQV VI KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK LFNQLFGE D D+DV PD  DPEL  +  +   Q++        ++      W     YD   +   LF D+I  LLSM++LW K  R  PE LD  SL N             TGG       + DQ  +S++     FK S + L SE   Q D   LVWDKD+  AMDFV AAANIR  +F I P+ +RF+IKSMAGNIIPAIATTNA+IAG+ V+ A KIL+G  + C  V ++   + R K++       P   CYVCS K E+T+   +T++ ++K L+  +++    ++AP+V + +    II   ++   E    K L  F + NG+  +C DFLQ Y   +  + VD  E + ++E++GDV  V
Sbjct:   14 EKVKSSRILVVGAGGIGCELLKNLVLTGFKDIEVIDLDTIDVSNLNRQFLFRKEHVGKSKAQVARESALKFNPDGKIKAYHDSVMSTEYDTEFFKQFDVVLNALDNRAARNHVNRMCLAADKPLVESGTAGYLGQVTVIKKGLTECYECQPKPHQKTFPGCTIRNTPSEPIHCIVWAKHLFNQLFGEADPDEDVSPDTEDPELAGDAGKQALQSEAKEDTVGGIERKSTRIWAQETGYDPMKIFNKLFRDDIHYLLSMESLWKK--RRPPEPLDFDSLPN-------------TGGSSDNMNLIHDQRIWSVQECADIFKQSVDLLKSELQKQGDAGILVWDKDEPAAMDFVTAAANIRAYIFGI-PIKSRFDIKSMAGNIIPAIATTNAIIAGLLVMEALKILSGNINDCRTVYLNRHPNSRKKLLVPCMLDPPNPKCYVCSSKPEVTVKVNTTSM-TVKSLEDKVIKGQFGLVAPDVELDDGKGTIIISSEEGETEENAAKPLSFFGIKNGSRIKCDDFLQEYNLNITLLHVDKLEEEKEFEVVGDVSEV 548          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPEL------TNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTG-GVKDQEKFSLRNWCQAFKNSANQLSERMS-QSDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDV-EHVISSAVSDSDR---NGNLNS--PPNS------------VDETADLNDSGTNVSGDR---KRKHEDSMEHELKHK 1776
            D+++   +LVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF++F +V+NALDN+AARN+VNRMCL ++IPLIE GT GY GQV VI KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE       T       DQ   +K      W  S  YD   L   LF D+I  LL+M  LW K  R  P  LD +    ++  L+       G G+KDQ+  ++  + + F++S   L  +++ + D A LVWDKDD  AMDFV AAAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL A K+LN    +C  + ++   + R K++       P  +CYVC+ K E+T+       I ++ L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL  D  +E++GD  +    S   + ++   NGN +S  P  S            VD   + + S  +VS +    KRKH+D+   E   K
Sbjct:   14 DSVSSCKILVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLRFCPSANITAYHDSIMNPDYNVEFFRSFQLVMNALDNRAARNHVNRMCLAADIPLIESGTAGYLGQVTVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPEDTAARATASDQDGDIKRVSTKDWARSTGYDPVKLFNKLFKDDIMYLLTMDKLWKK--RKAPVPLDWA----EMLQLANPQDEGCGTGLKDQQVLNVGGYSRLFQHSVETLRSQLADKGDGAELVWDKDDPPAMDFVTAAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEALKVLNSDIQQCRTIFLNKQPNPRKKLLVPCALDRPNPNCYVCASKPEVTVKLNVHKTI-VQALQDKILKEKFGMVAPDVQIEDGKGTILISSEEGETEANNGKMLSDFGIRNGSRLQADDFLQDYTLLVNVLHSEELPKDVEFEVVGDAPDKAPPSKAPEEEKSITNGNKDSAQPSTSSKAVVEEDDLLIVDSDEEPSSSTADVSTETSSLKRKHQDAETGEAASK 623          

Query:    1 IF*SRMDNI-AKSNVLVVGAGGIGCELLKNLVMWNFK----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNK---YNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
            +F S+M  + AK    +VGAG IGCELLKN  M        E+ V D+DTI+ SNLNRQFLFR  +V K K+ TA  +V + NP+V I    + V  +    Y+ DFF++ D V NALDN  AR Y++R C+    PL+E GT+G +G VQV++   T  Y     P +K  P CT++N P+   H + WA+  F  LF +P
Sbjct:  458 VFGSKMQELLAKQRYFLVGAGAIGCELLKNFAMMGLASGEGEVIVTDMDTIEKSNLNRQFLFRPWDVTKMKSETAAAAVKQMNPSVRITGHQNRVGPDTEKVYDDDFFESLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVMPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 659          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQV 426
            M  +  SNVL+ G  G+G E+ KN+++   K +T+ D    + ++L+ QF  R+E++GK++A  ++  + + N  V + A      + +   D+   F +V+        +  +   C    I LI   T G  GQ+
Sbjct:   67 MKRMQSSNVLISGLRGLGVEIAKNVILGGVKTVTLHDQGVAEWNDLSSQFYLREEDLGKNRAEVSQTRLAELNSYVPVTA-----YTGELTDDYLTDFQVVVLTSSTIDEQTRIGEFCHSKGIKLIIADTRGLFGQL 198          

Query:    1 IF*SRMDNI-AKSNVLVVGAGGIGCELLKNLVMWNFK----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNK---YNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
            +F S+M  + AK    +VGAG IGCELLKN  M        E+ V D+DTI+ SNLNRQFLFR  +V K K+ TA  +V + NP+V I    + V  +    Y+ DFF++ D V NALDN  AR Y++R C+    PL+E GT+G +G VQV++   T  Y     P +K  P CT++N P+   H + WA+  F  LF +P
Sbjct:  455 VFGSKMQELLAKQRYFLVGAGAIGCELLKNFAMMGLASGEGEVIVTDMDTIEKSNLNRQFLFRPWDVTKMKSETAAAAVKQMNPSVRITGHQNRVGPDTEKVYDDDFFESLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVMPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 656          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQV 426
            M  +  SNVL+ G  G+G E+ KN+++   K +T+ D    + ++L+ QF  R+E++GK++A  ++  + + N  V + A      + +   D+   F +V+        +  +   C    I LI   T G  GQ+
Sbjct:   64 MKRMQSSNVLISGLRGLGVEIAKNVILGGVKTVTLHDQGVAEWNDLSSQFYLREEDLGKNRAEVSQTRLAELNSYVPVTA-----YTGELTDDYLTDFQVVVLTSSTIDEQTRIGEFCHSKGIKLIIADTRGLFGQL 195          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNI----KAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLKNL +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + V    P  ++    K I D      ++  F++ F I++  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HC+ + + L  Q   E      V  D ++PE
Sbjct:   56 ILVIGAGGLGCELLKNLALSGFRHIHVVDMDTIDVSNLNRQFLFRSKDVGRPKADVAADFVNSRVPGCHVVPHFKKIQD------FDESFYRQFHIIVCGLDSIIARRWMNGMLLSLLVYEDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCIEYVRIL--QWPKEKPFGDGVALDGDNPE 260          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNI----KAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLKNL +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + V    P  ++    K I D      ++  F++ F I++  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HC+ + + L  Q   E      V  D ++PE
Sbjct:   67 ILVIGAGGLGCELLKNLALSGFRHIHVVDMDTIDVSNLNRQFLFRSKDVGRPKADVAADFVNSRVPGCHVVPHFKKIQD------FDESFYRQFHIIVCGLDSIIARRWMNGMLLSLLVYEDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCIEYVRIL--QWPKEKPFGDGVALDGDNPE 271          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF---NQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLK+L +  F++I VID+DTIDVSNLNRQFLFR ++VG+ KA  A E +    P  N+          +Y+  F++ F I++  LD+  AR ++N M +             + IP+I+GGT G++G  +V+L G TAC EC     P Q  +P CT+ + P  P HC+ + + L     Q FG+      V  D +DPE
Sbjct:   58 ILVLGAGGLGCELLKDLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKANVAAEFINTRVPGCNVMPYPSFSNIQEYDESFYRQFHIIVCGLDSIVARRWINGMLMSMLNFEDGVLDPSTIIPMIDGGTEGFKGNARVVLPGMTACIECTLDLYPPQINFPICTLASMPRLPEHCIEYVRLLQWPKEQPFGD-----AVALDGDDPE 264          

Query:   34 SNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRG 420
            S +L+VG  G+G E+ KNL++   K +T +D +     +   QFL  +  +G++ A  + E     NP V+++    D+ S     +FF  FD +      +     +NR+C + NI    G   GY G
Sbjct:   38 SKLLIVGMKGLGAEVAKNLILAGVKSVTFLDNNKATEESTRAQFLVPQSRLGENLAEASLERAQNLNPMVDVRTDKSDIASK--TEEFFTQFDSICLTGCPQDVMIKINRICHERNIKFFAGDVFGYHG 164          

Query:  112 ITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNA-DFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYEC 465
            + ++D D++++SNL+RQ L  ++ VG+ KA +A  +V +   N  ++ +   ++ ++ NA    + +D+V +  DN A R  V+ +C+ +  PL+    +   GQ+ V       CY C
Sbjct:    3 LGLVDHDSVELSNLHRQVLHTEQRVGEEKAASAACAVAQIRLNSTVEVVPYHLLLSQKNALQLVRQYDVVADCSDNVATRYLVSDVCVLAGKPLVSASALRMEGQLTVYNHEGGPCYRC 121          

Query:   58 GGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFF------------KTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTM--GYRGQVQVILKGKTACYECYP 471
            GG+G    + L      ++ + D D ++++N+NR F F+ +  G SK   A+ ++   NP+V  +  H+  ++   N   F            +  ++VL  +DN  AR  +N  C + +   IE G       G +Q+I+ G+TAC+ C P
Sbjct:   33 GGVGSVTAEMLTRCGVGKLLLFDYDKVELANMNRLF-FQPQQAGMSKVEAAEHTLRNINPDVQFET-HNYNVTTMGNFQHFMERVSHGGLQEGRPVELVLCCVDNFEARMAINTACNELSQVWIESGVSENAVSGHIQLIIPGETACFACAP 182          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENV---GKSKALTAKESVLKFNPNV 243
            ++ ++ +  L++GAG +GC + + L+ W  + IT +D   +  SN  RQ L+  E+    GK KA  A E + +  P V
Sbjct:  331 LEAVSTARCLLLGAGTLGCNVARTLLGWGVRHITFVDNARVSYSNPVRQTLYEFEDCLGGGKPKAQAAAERLRRIFPGV 409          

Query:   34 SNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMS-NKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAK-FLFNQLFG------EPDADQDVVPDQNDPELTNETTENGDQTDPVKLNI-RLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILN----GQADKCLDVMVSDFVS-----GRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFE----KTLDQFDVANGTVFRCS----DFLQNYEFVLEIKVDSELKNDYEILGDVE 1611
            S  L+VGAGGIG ELLK++++  F EI ++DLDTID+SNLNRQFLFR++++ + K+ TA ++V  FN N  +     +VM  + +   +F+ FDI+ NALDN AAR YVN++    ++PLIE GT G+ G +Q I+ GKT C+EC  K   K +P CTIR+TPS+PIHC+VWAK FLFNQLF       E D +QD   D  + E+     E  +  +  K+ I R A ++ +      +L  LF  +I  LL+++ LW    R KP  L  S IN      +Q  SN  G +++Q           F N   +L +R  +    + +DKDD   ++FVA AANIR  +F+I PM + F+IK +AGNIIPAIATTNA++AG S L + ++LN        K  D+ ++ F +      + + + + +   P K+C VCSK      +C+    +S   L    L + + ++    +     S++   +   + +  FE    +TL + ++ NG++   S    D +      L + VD EL  +   L DVE
Sbjct:   22 SRCLLVGAGGIGSELLKDIILMEFGEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAVQHFN-NSKLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPKTFPVCTIRSTPSQPIHCIVWAKNFLFNQLFASETSGNEDDNNQDWGTDDAE-EIKRIKQETNELYELQKIIISRDASRIPE------ILNKLFIQDINKLLAIENLW--KTRTKPVPLSDSQINTPT-KTAQSASNSVGTIQEQ--------ISNFINITQKLMDRYPKEQNHIEFDKDDADTLEFVATAANIRSHIFNI-PMKSVFDIKQIAGNIIPAIATTNAIVAGASSLISLRVLNLLKYAPTTKYTDLNMA-FTAKASNLSQNRYLSNPKLAPPNKNCPVCSK------VCRGVIKLSSDCLNKMKLSDFVVLIREKYSYPQDISLLDASNQRLLFDYDFEDLNDRTLSEINLGNGSIILFSDEEGDTMIRKAIELFLDVDDELPCNTCSLPDVE 546          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKE-----ITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVN--IKAIHDDVMSNK---YNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLF 573
            IA S V +VG+G IGCE+LKN  +          I V D D+I+ SNLNRQFLFR ++VGK+K+  A E+V   NP++   I A  D V       +N  F+++ D V NALDN  AR YV+R C+    PL+E GT+G +G  QVI+   T  Y     P +K  P CT+R+ P++  H + WAK LF   F
Sbjct:  432 IANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRDPPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYF 624          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIH--DDVMSNKYNADFFKTFDIVLNALDNKAARNYV--NRMCLKSNIPLIEGGTMGYRGQVQVIL 438
            M  +  SNVL++G  G+G E+ KN+V+   K +TV D + + +++L+ QF   ++++G+ +    +  + + N  V +  +   DDV            F +V+ A D  +  + V  N  C  S I  I   T G  G   V L
Sbjct:   31 MLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQ-------LSQFQVVV-ATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDL 167          

Query:   40 VLVVGAGGIGCELLKNLVMWNF-KEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVN----RMCLKSN----IPLIEGGTMGYRGQVQVILKGKTACYECY--PKPAQK-QYPACTIRNTPSEPIHCVVWAK 552
            +LV+GAGG+GCE+LKNL M +F K++ ++D+DTI+++NLNRQFLF  +++GK KA  A + V    P + + A   D+ +      F+K F  +++ LD    R ++N    ++ L+SN    IP I+GGT G +G V+ I+ G TAC+EC     P+Q+   P CTI N P    H V +  
Sbjct:    5 ILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTT--LPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVS 185          

Query:   34 SNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNA-DFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVI-LKGKTACYEC-YPKP 477
            + VLVVGAGG+GC  L  L      +I ++D D ++ SNL+RQ L     VG  K  +A++ + K NP++N+  +   V  N  NA D FK ++ +L+  D+   R  V+ + +   I ++    +G  GQ+ ++       CY C YP P
Sbjct:   68 TKVLVVGAGGLGCPALPYLAGAGVGQIGIVDNDVVETSNLHRQVLHDSSRVGMLKCESARQYITKLNPHINV--VTYPVRLNSSNAFDIFKGYNYILDCTDSPLTRYLVSDVAVNLGITVVSASGLGTEGQLTILNFNNIGPCYRCFYPTP 216          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAI--------HDDVMSNKYNADF------FKTFDIVLNALDNKAAR 348
            +D I  + VL++GAG +GC + + L+ W  ++IT +D  T+  SN  RQ L+  E+ GK KA  A  S+ +  P ++   +        H  V     + DF       K  DI+   +D++ +R
Sbjct:  319 LDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESR 443          

Query:   10 SRMDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNE----------TTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRK 1740
            S  D +  S +LVVGAGGIGCELLKNLV+  FK I +IDLDTIDVSNLNRQFLF K++VGKSKA  A+ES L+FNP+  I AIHD++ S +Y  D+FK FD+V+NALDN+AARN+VNRMCL +++PL+E GT GY GQ  VI KG T CYEC PKP QK +P CTIRNTPSEPIHC+VWAK LFNQLFGE DAD++V PD  DPE   E             NG +    + + RL W     Y+   L   LFN++I+ LLSM  LW K     P + D     V  +  S    +    ++DQ  +S++   + F  S   L   +S     L WDKDD  +MDFV  AANIR  +F I PM +RF+IK+MAGNIIPAIATTNA+I+GI V+    IL G+ DKC  + ++   + R +I+     + P   CYVC+ K E+  +  +T  ++++ L+  +L+    M+AP+V I +    II   +    E    K L +F++ NG+  +  DFLQNYE V+ IK  ++L+ D  +E+ GD+    S   +  + +     P N    + D      N +  RKRK
Sbjct:   16 SLADKVNNSKILVVGAGGIGCELLKNLVLTGFKNIDLIDLDTIDVSNLNRQFLFHKQHVGKSKAKVARESALRFNPDAKIVAIHDNITSPEYGIDYFKQFDVVMNALDNRAARNHVNRMCLAADVPLVESGTAGYLGQTTVIKKGVTECYECQPKPTQKSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGEADADEEVSPDTEDPEAVGEAGANAAQDGAAANNGGEIQ--RQSTRL-WAEQIGYNPLKLFNKLFNEDIKYLLSMDKLWKKRTPPTPLLWD----TVTTESHSSENGSDDSQLQDQRVWSVQECAKKFSTSIESLKIELSTKGEDLSWDKDDPASMDFVCCAANIRAQIFGI-PMKSRFDIKAMAGNIIPAIATTNAVISGIIVMQGLNILAGKLDKCKTIYLNRQPNPRKRILVPCALVEPNPKCYVCASKPEVVTVFVNTETMTIQALEEKVLKERFGMIAPDVEIDDGKGTIIISSEQGETEDNLPKALAEFNIINGSRLKADDFLQNYELVINIKHRTDLETDQEFEVEGDIPEPGSPGPAPVEPSNEPGLPSNGDTASQDELMVVENATPSRKRK 596          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFK-----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDAD-------------QDVVPDQNDPELTNETTENGDQTDPVKLNIRLAW--KVSDQYDSNLLLKILFNDNIRDLLSM-KALWMKSERV-KPEVLD-KSLINVDI----DDLSQFMSNVTG-----------------------GVK----DQEKFSLRNWCQ--------AFKNSANQLSERMSQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILN 1182
            + +    VVGAG IGCE LKN  M          I   D+DTI+ SNLNRQFLFR  +V K K+  A  +V   NP+VNI A  + V       YN DFF++   V NALDN  AR Y++R C+    PL+E GT+G +G VQV+L   T  Y     P +K  P CT++N P+   H + WA+  F  LF  P  +              D +P     E+ +   +      P      ++W   +  +Y  N + ++LFN     + S  +  W   +R   P V D +   ++D      +L  +M  +TG                       GVK    DQE  + RN  +        A     +    +M+ +D     D D    MDF+ AA+N+R + + I P   R + K +AG IIPAIATT A+++G+  L  YK++ 
Sbjct:  416 LGQQKYFVVGAGAIGCEHLKNFAMMGLGSGEGGHIYTTDMDTIEKSNLNRQFLFRPADVQKMKSEVAARAVKVMNPDVNITAHGNRVGPETEKVYNDDFFESLSGVTNALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVLPFMTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDAFEGLFTIPAENVNQYVCDPKFIERTDKLPGMQAMEVYDSVKKCLVDERPKDFAGCVSWARHLFQEYYHNTIKQLLFNFPADQMTSSGQPFWSGPKRCPHPLVFDPREGTHLDFISAAANLRAYMYGITGSKDQQYILDILKGITVPEFVPKSGVKIAVTDQEAEAERNTDEDDVDSVKSAMPTPESLQGFKMNPAD--FEKDDDTNFHMDFIVAASNLRAANYDIPPA-DRHKSKLIAGKIIPAIATTTAIVSGLVCLELYKLVQ 863          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQV 426
            M  +A SNVL+ G  G+G E+ KN+V+   K +T+ D   +++S+L  QF   K++VGK++A  +   + + N  V++      V + K   +F   F +V+    +   + +++  C    I LI   T G  GQ+
Sbjct:   20 MKKMAVSNVLISGLRGLGVEIAKNVVLGGVKSVTLHDTGAVELSDLTSQFFLNKKDVGKNRAEVSHPRIAELNTYVSMS-----VNTQKLTEEFINKFQVVVLTESSLEEQLWISDFCHSKGIKLIISDTKGLFGQI 151          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKE----SVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCL-------------KSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLF 561
            +  + VLV+GAGG+GCELLK+L +  F++I VID+DTID+SNLNRQFLFR +++G+ KA  A E     +   N   + + I D      Y+  F+K F IV+  LD+  AR ++N M +              S IP+++GGT G++G  ++++ G TAC EC     P Q  +P CTI +TP  P HC+ +AK L 
Sbjct:   39 LESAKVLVIGAGGLGCELLKDLALCGFRDIHVIDMDTIDISNLNRQFLFRPKDIGRPKADVAAEFINSRIAGCNVTPHFRKIQD------YDTGFYKNFHIVVCGLDSIFARRWINGMLMSLLEYDEDGNLDQSSLIPMVDGGTEGFKGNARIVVPGITACIECTLDLYPPQVNFPLCTIAHTPRLPEHCIEYAKVLL 230          

Query:   25 IAKSNVLVVGAGGIGCELLKNLVMWNFKE-----ITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKA----IHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGE 579
            IA   + +VG G IGCE LKN  +          I++ D D I+ SNLNRQFLFR  ++ K+K+ T+  S  + NP+++I+A    +  D   + +N  FF++ ++V+NALDN  AR YV+  C+ +   L+E GTMG +G VQVI+   T  Y     P  ++ P CT+++ P+   HC+ WA+  F   F +
Sbjct:  413 IADLKLFMVGCGAIGCEFLKNFALLGIASGNNGLISITDNDLIEKSNLNRQFLFRPHHIQKAKSTTSATSTKEINPSLHIEAHQQKVCPDTEQDTFNDAFFESQEVVVNALDNVEARRYVDSRCVSNQRALLETGTMGAKGHVQVIVPHLTESYTSQRDPVDQEVPYCTLKSFPAIIEHCIQWARDKFESSFTQ 606          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKS--KALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVL 321
            M  +A ++V + G GG+G E+ KNL +   K IT+ D     +++L  QF  R+++V  S  +A+ +   V + NP V++    D +  N  N D  K +  V+
Sbjct:    7 MQKMAHASVFLSGVGGLGVEIAKNLTLAGIKSITLHDTRAASMADLGSQFFLREDDVTSSRNRAVASAGRVAELNPYVSVHTQTDALDEN--NLDVLKNYQCVI 108          

Query:   22 NIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNA-DFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYEC-YPKP 477
            ++  S+VLVVGAGG+GC     L       + ++D D +D SNL+RQ L  ++ V   K  +AK+++L+ N +         +  N  NA D    +D++++A DN A R  +N  C+ +  PL+ G  +   GQ+ V       CY C +P P
Sbjct:   43 SLKSSSVLVVGAGGLGCPAALYLAAAGIGCLGLVDYDVVDTSNLHRQVLHTEDRVEVPKVESAKQTLLRLNSDAQYNT--HCLQLNSVNALDIINKYDVIVDATDNVATRYLLNDACVLAKKPLVSGSALRLEGQLVVYNHDNGPCYRCLFPTP 194          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELT----------NETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQL-SERMSQSDTA-LVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELT--LLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKND--YEILGDVEHVISSAVSDSDR-----NGNLNS--PPNSVDETADLND--------------SGTNVSGDRKRKHED 1749
            D++    VLVVGAGGIGCELLKNLV+  FK I VIDLDTIDVSNLNRQFLF+K++VGKSKA  AKESVL+F P+ NI A HD +M+  YN +FF+ F +V+NALDN+AARN+VNRMCL +++PLIE GT GY GQV VI KG T CYEC PKPAQK +P CTIRNTPSEPIHC+VWAK+LFNQLFGE DADQ+V PD  DPE            + + ++GD    VK      W  S  YD   L   LF D+I  LL+M  LW K  R  P  LD + +    +  S    +   G+KDQ+   +   CQ FK+S   L SE   + D A LVWDKDD  AMDFV +AAN+RM +F  + M +RF++KSMAGNIIPAIATTNA+IAG+ VL   KIL+G+ + C  + ++   + R K++       P K+CYVC+ K E+T  L  + T ++S   L+  IL+    M+AP+V I++    I+   ++   E    K L  F + NG+  +  DFLQ+Y  ++ +    EL+ D  +E++G+         S+ +      NGN +S  P  S    AD +D              S   V+   KRKH D
Sbjct:   14 DSLYTCKVLVVGAGGIGCELLKNLVLTGFKNIEVIDLDTIDVSNLNRQFLFQKKHVGKSKAQVAKESVLQFCPSANITAYHDSIMNPDYNVEFFRKFMLVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTVIKKGLTECYECQPKPAQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDTADPEAAWNPEEAAARASASEKDGD----VKRVSTKEWARSTGYDPIKLFNKLFKDDIMYLLTMDKLWKK--RKAPTPLDWTQLE---NKASPEEESPASGLKDQQVLGVWGCCQLFKHSVETLRSELREKGDNAELVWDKDDPAAMDFVTSAANLRMHIFS-MNMKSRFDVKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGELESCRTIFLNKCPNVRKKLLVPCVLDPPSKNCYVCASKPEVTVKLNVQKTTVLS---LQDRILKERFGMVAPDVQIEDGKGTILISSEEGETEANNSKYLSDFGIRNGSRLQSDDFLQDYTLLINVLHTEELERDVEFEVVGEAPDKAPPPQSNPEEVNSITNGNKDSAQPSTSSKAPADEDDLMIVDSDEEEGAPSSSATVTSGTKRKHSD 614          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFK----EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEP 582
            D +A+    +VGAG IGCELLKN  M        E+ V D+DTI+ SNLNRQFLFR  +V K K+ TA  +V + NP++ I    + V       Y+ DFF++ D V NALDN  AR Y++R C+    PL+E GT+G +G VQV++   T  Y     P +K  P CT++N P+   H + WA+  F  LF +P
Sbjct:  465 DLLARQRYFLVGAGAIGCELLKNFAMIGLASGEGEVIVTDMDTIEKSNLNRQFLFRPSDVTKMKSDTAAAAVKQMNPSIRITGHQNRVGPETERVYDDDFFESLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQP 659          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQV 426
            M  +  SNVL+ G  G+G E+ KN+++   + +TV D    +  +L+ QF  R+E++GK++A  ++  + + N  V + A      +     D+   F +V+        + +    C    I +I   T G  GQ+
Sbjct:   67 MKRMQNSNVLISGMRGLGVEVAKNVILGGVRSVTVHDQGVAEWRDLSSQFYLREEDLGKNRAEMSQLRLAELNNYVPVTA-----YTGALTEDYLTKFQVVVLTNSTLDEQKHFGDFCHSKGIKIIIADTRGLFGQL 198          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNV----NIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLK------------SNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLK+L +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + +    P      + K I D       +  F++ F I++  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HC+ + + L  Q   E      V  D +DPE
Sbjct:   51 ILVIGAGGLGCELLKDLALTGFRNINVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFINSRVPGCCVVPHFKKIQD------LDETFYRQFHIIVCGLDSIVARRWMNGMLLSLLVYEDGVLDPGSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCIEYVRIL--QWPKELPFGDGVALDGDDPE 255          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNV----NIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLK------------SNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLK+L +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + +    P      + K I D       +  F++ F I++  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HC+ + + L  Q   E      V  D +DPE
Sbjct:   60 ILVIGAGGLGCELLKDLALTGFRNINVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFINSRVPGCCVVPHFKKIQD------LDETFYRQFHIIVCGLDSIVARRWMNGMLLSLLVYEDGVLDPGSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCIEYVRIL--QWPKELPFGDGVALDGDDPE 264          

Query:   40 VLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNV----NIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLK------------SNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPE 624
            +LV+GAGG+GCELLK+L +  F+ I V+D+DTIDVSNLNRQFLFR ++VG+ KA  A + +    P      + K I D       +  F++ F I++  LD+  AR ++N M L             S IPLI+GGT G++G  +VIL G TAC +C  +  P Q  +P CTI + P  P HC+ + + L  Q   E      V  D +DPE
Sbjct:   71 ILVIGAGGLGCELLKDLALTGFRNINVVDMDTIDVSNLNRQFLFRPKDVGRPKAEVAADFINSRVPGCCVVPHFKKIQD------LDETFYRQFHIIVCGLDSIVARRWMNGMLLSLLVYEDGVLDPGSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPPQINFPMCTIASMPRLPEHCIEYVRIL--QWPKELPFGDGVALDGDDPE 275          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTALVWDKXXXXXXXXXXXXXNIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVNIQNKSSVXXXXXXXXXXXVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKNDYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSMEHELKHKIAKMXXXXXXXXXXXXXXLIMVE 1845
            MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTALVWDKDDVVAMDFVAAAANIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNV+IQNKSSVIIDGDDDEIDEVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKNDYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSMEHELKHKIAKMDSQVDIDNEDDQDDLIMVE
Sbjct:    1 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDADQDVVPDQNDPELTNETTENGDQTDPVKLNIRLAWKVSDQYDSNLLLKILFNDNIRDLLSMKALWMKSERVKPEVLDKSLINVDIDDLSQFMSNVTGGVKDQEKFSLRNWCQAFKNSANQLSERMSQSDTALVWDKDDVVAMDFVAAAANIRMSVFHILPMLTRFEIKSMAGNIIPAIATTNAMIAGISVLHAYKILNGQADKCLDVMVSDFVSGRGKIVQSVQPLSPVKDCYVCSKKLELTLLCKSTNLISLKLLKVAILENHLKMLAPNVSIQNKSSVIIDGDDDEIDEVYFEKTLDQFDVANGTVFRCSDFLQNYEFVLEIKVDSELKNDYEILGDVEHVISSAVSDSDRNGNLNSPPNSVDETADLNDSGTNVSGDRKRKHEDSMEHELKHKIAKMDSQVDIDNEDDQDDLIMVE 610          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYE 462
            MDN+AKSNVLVV A GIGCELLKNLVM N KEI VIDLDTIDV NLNRQFLFRK+NVGKSKALTAKESVLKFNPNVN+KAI+DDVMSNKYNADFFKTFDIVL ALDNKAARNYV+RMCL+SN  LI+GGTMGYRGQVQVILKGKTACYE
Sbjct:    1 MDNVAKSNVLVVSAVGIGCELLKNLVMRNLKEIAVIDLDTIDVGNLNRQFLFRKKNVGKSKALTAKESVLKFNPNVNLKAINDDVMSNKYNADFFKTFDIVLKALDNKAARNYVSRMCLRSNNQLIKGGTMGYRGQVQVILKGKTACYE 149          

Query:  175 KENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFL 558
            +   GKSK LTAKE+VLKFN NVNIKAIHDD                   A++NKAARNYVNRMCLKSNI LIEGGTMGYRGQVQVILK KTACYECYPKP QKQ PACTIRNTPSEPIHC VWAKF 
Sbjct:    3 QRKCGKSKLLTAKETVLKFNTNVNIKAIHDD-------------------AMNNKAARNYVNRMCLKSNITLIEGGTMGYRGQVQVILKDKTACYECYPKPVQKQSPACTIRNTPSEPIHC-VWAKFF 110          

Query:   37 NVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVNRM-------------CLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPK--PAQKQYPACTIRNTPSEPIHCVVWAKFL 558
            ++LV+GAGG+GCELLK++ M  F  I VID DTID+SNLNRQFLFR  ++GK K++ A   ++   P+   K I        +++ F+K F +V+  LD+  AR ++N M              L S IPLI+GGT G++G  +VIL GKT C EC     P Q  YP CT+ NTP  P HC+ + + +
Sbjct:   42 SILVIGAGGLGCELLKDIAMMGFSNIEVIDADTIDLSNLNRQFLFRTHDIGKPKSIVAANYIMSRIPDC--KVIPHFAKIQDFDSSFYKKFHVVVCGLDSIVARRWINGMLASLVEYNDIGEPILSSIIPLIDGGTEGFKGNARVILFGKTPCIECTLDFYPPQINYPLCTLANTPRLPEHCIEYVRVI 228          

Query:   19 DNIAKSNVLVVGAGGIGCELLKNLVMWNFK-----------EITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDV---MSNKYNADFFKTFDIVLNALDNKAARNYVNRMCLKSNIPLIEGGTMGYRGQVQVILKGKTACYECYPKPAQKQYPACTIRNTPSEPIHCVVWAKFLFNQLFGEPDA 588
            + ++K  + +VGAG IGCELLKN VM               +I V D+D+I+ SNLNRQFLFR +++GK K+LTA E+    NP V I+A+   V     + +N  FF    +V NALDN  AR Y++R C+    PL+E GT+G +  VQV+L   T  Y     P +K  P CTI+N P    H + WA+ LF  LF +P A
Sbjct:  468 EKLSKLKIFLVGAGAIGCELLKNFVMMGVGASINDSDDDSGKIVVTDMDSIERSNLNRQFLFRSKDIGKMKSLTAAEAAKCMNPYVRIEALELKVGKETESYFNDAFFNDISVVANALDNVEARQYMDRRCVFYLKPLLESGTLGTKCNVQVVLPHLTESYSSSQDPPEKSIPVCTIKNFPYLIEHTIQWARDLFEGLFSQPAA 671          

Query:   16 MDNIAKSNVLVVGAGGIGCELLKNLVMWNFKEITVIDLDTIDVSNLNRQFLFRKENVGKSKALTAKESVLKFNPNVNIKAIHDDVMSNKYNADFFKTFDIVLNALDNKAARNYVN--RMCLKSNIPLIEGGTMGYRGQV 426
            M N++KSN+L+ G GG+G E+ KN+++   K +T+ D  +    +L+ Q+   + N+G+++A +  + + + N  VN+     +V +N    +    F+IV+  L N      +N    C  +NI LI   T G  GQ+
Sbjct:   60 MKNMSKSNILISGMGGLGVEIAKNVILAGVKSVTLHDELSATECSLSSQYYLNENNIGQNRATSCFKHLAELNSYVNV-----NVDTNPLTKEMLLNFNIVV--LTNIKQDEIINITGFCHLNNIKLIITRTFGLFGQI 191