carboxypeptidase E
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002098 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of carboxypeptidase E vs. Ensembl Human
Match: CPN1 (carboxypeptidase N subunit 1 [Source:HGNC Symbol;Acc:HGNC:2312]) HSP 1 Score: 212.616 bits (540), Expect = 9.803e-63 Identity = 126/394 (31.98%), Postives = 199/394 (50.51%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKR-----VYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKP 1251
+ H ++LV + K+ +CP IT +Y I +++ LYV F +P H PE ++ N+HGNE +GRE + ++++LC ++ R++ I +LI RIH L SMNPDGY + + G+ G NN DLN +FPDL T + EK + +H + + + ET + W+ + +VL NLH +V NY Y +S + R PTPDD +++ + + H M + W C Y+ P+ + G++W S+ G DF+YL TN L LSC + +Q W + +L+ + QVH G+KG+V DE N + NAVI + + +G+ GDY+R+L+PG Y + + GY P
Sbjct: 24 RHHRYDDLVRTLYKVQNECPGITRVY-----SIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYN-EK--YGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGW--NCGDYF---PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHD--------VTSGDHGDYFRLLLPGIYTVSATAPGYDP 396
BLAST of carboxypeptidase E vs. Ensembl Human
Match: CPE (carboxypeptidase E [Source:HGNC Symbol;Acc:HGNC:2303]) HSP 1 Score: 213.001 bits (541), Expect = 1.062e-62 Identity = 137/417 (32.85%), Postives = 212/417 (50.84%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG----FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGST----WLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPS 1323
H EL + ++ + +C I+ +Y + ++ L V P H G PEF +I N+HGNE +GRE I +A YLCN+Y + +E I LI+S RIH + S+NPDG+ G + G +N DLN +FPDL + + + E +HL KK +++ K ET ++W++ +P+VL NLH LV NY Y ++ Y+ +PDD I++ + + + +P M + R P ++ G+T W SV G DF+YLS+N + LSC++ ++ +W + SL+ Y Q+H GVKG VRD +GN I NA I +V D + + + + GDY+R+LIPG+Y + S GY + K + A +DFEL S
Sbjct: 54 HRYPELREALVSVWLQCTAISRIYT-----VGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVY--VNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPN-RPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATI-SVEGIDHD-------VTSAKDGDYWRLLIPGNYKLTASAPGY---LAITKKVAVPYSPAAGVDFELES 451
BLAST of carboxypeptidase E vs. Ensembl Human
Match: CPXM1 (carboxypeptidase X, M14 family member 1 [Source:HGNC Symbol;Acc:HGNC:15771]) HSP 1 Score: 210.305 bits (534), Expect = 1.419e-59 Identity = 134/419 (31.98%), Postives = 211/419 (50.36%), Query Frame = 1
Query: 55 LILVSTVAVYCFQLNKQHSN-EELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLE--KLEHNMTDH---LFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQY-KRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVR-CPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGN-RIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
L L + + L+ QH N + + +M ++ ++CPNIT +Y I K+ +LYV P H G PE +++ +HGNE +GRE +L+ +LC+++L + +T+L+ MRIH L SMNPDGY + +++ G+ EG N DLNH+F DL T ++ + K+ H + +H L T ET + W+ +P+VL NLH LV +Y + + + R PTPDD ++R++ + + + M++ R C + V + G+ W +V +DFSYL TN + LSC + + W + +LL Y QV MG+ GVVRD++ I +AVI I + T GDY+R+L PGDY + S +GY R +V
Sbjct: 282 LFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIY-----SIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDG--------INHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRV 687
BLAST of carboxypeptidase E vs. Ensembl Human
Match: CPM (carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311]) HSP 1 Score: 201.83 bits (512), Expect = 9.574e-59 Identity = 138/435 (31.72%), Postives = 215/435 (49.43%), Query Frame = 1
Query: 31 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP--TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAI-RCFKVDNLDKFSAKVIDFELP 1320
M+F L L +L+ VA F ++Q E + + + N +++ +L I K++ L+V V G++P H GIPEF +++N+HG+E +GRE + + DYL +D IT LI S RIH + SMNPDG+ + + D Y + G NY DLN +FPD E+N Q ET+ M WL T +VL NLH LV +Y + + +Y+ TPDD++++Y+ + +R+P MK+ C + PN + G +W ++ G D++Y+ L LSC + + W + SL+ Y +QVH+GVKG V D+ GN + N +++ + PY RT + G+YY +L+PG Y I V+ G+ P I + + FSA D LP
Sbjct: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQ------NYSSVTHLH--SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY-YSIGRENYNQYDLNRNFPD----------AFEYNNVSR------------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY------RTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILLP 395
BLAST of carboxypeptidase E vs. Ensembl Human
Match: CPM (carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311]) HSP 1 Score: 201.83 bits (512), Expect = 9.574e-59 Identity = 138/435 (31.72%), Postives = 215/435 (49.43%), Query Frame = 1
Query: 31 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP--TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAI-RCFKVDNLDKFSAKVIDFELP 1320
M+F L L +L+ VA F ++Q E + + + N +++ +L I K++ L+V V G++P H GIPEF +++N+HG+E +GRE + + DYL +D IT LI S RIH + SMNPDG+ + + D Y + G NY DLN +FPD E+N Q ET+ M WL T +VL NLH LV +Y + + +Y+ TPDD++++Y+ + +R+P MK+ C + PN + G +W ++ G D++Y+ L LSC + + W + SL+ Y +QVH+GVKG V D+ GN + N +++ + PY RT + G+YY +L+PG Y I V+ G+ P I + + FSA D LP
Sbjct: 1 MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQ------NYSSVTHLH--SIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCY-YSIGRENYNQYDLNRNFPD----------AFEYNNVSR------------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD-ECKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY------RTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILLP 395
BLAST of carboxypeptidase E vs. Ensembl Celegans
Match: egl-21 (Carboxypeptidase E [Source:UniProtKB/Swiss-Prot;Acc:O17754]) HSP 1 Score: 218.779 bits (556), Expect = 2.646e-65 Identity = 141/417 (33.81%), Postives = 208/417 (49.88%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQR--ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ--YKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTY---WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDE-EGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
H+ +L + +I++KCP ITT+Y +I +++ L V F P H PE I N+HGNE IGRE + A+ LCN + D+ I +L+ S IH L SMNPDG+ L G +N DLN DFPDL + F+ +L+K+ DHL + E R ET+ W L++P+VL N H LV NY + ++D+ K Y+ +PDD +R++ + H M K C + G+ W SV G DF+YL+TN M L LSC++ + + W + S+ Y + H GVKG+V D G I AV+ N T++ P + + T GD+YR+L G Y I+V+ +GY A + V+N + SA V++F L
Sbjct: 41 HNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFY-ELQKIGVPKFDHLLS---LFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTGEPIKRAVVWIRNGTETVP--VKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFAL 446
BLAST of carboxypeptidase E vs. Ensembl Celegans
Match: egl-21 (Carboxypeptidase E [Source:UniProtKB/Swiss-Prot;Acc:O17754]) HSP 1 Score: 218.779 bits (556), Expect = 2.646e-65 Identity = 141/417 (33.81%), Postives = 208/417 (49.88%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQR--ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ--YKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTY---WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDE-EGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
H+ +L + +I++KCP ITT+Y +I +++ L V F P H PE I N+HGNE IGRE + A+ LCN + D+ I +L+ S IH L SMNPDG+ L G +N DLN DFPDL + F+ +L+K+ DHL + E R ET+ W L++P+VL N H LV NY + ++D+ K Y+ +PDD +R++ + H M K C + G+ W SV G DF+YL+TN M L LSC++ + + W + S+ Y + H GVKG+V D G I AV+ N T++ P + + T GD+YR+L G Y I+V+ +GY A + V+N + SA V++F L
Sbjct: 41 HNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFY-ELQKIGVPKFDHLLS---LFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTGEPIKRAVVWIRNGTETVP--VKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFAL 446
BLAST of carboxypeptidase E vs. Ensembl Celegans
Match: egl-21 (Carboxypeptidase E [Source:UniProtKB/Swiss-Prot;Acc:O17754]) HSP 1 Score: 218.779 bits (556), Expect = 2.646e-65 Identity = 141/417 (33.81%), Postives = 208/417 (49.88%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQR--ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ--YKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTY---WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDE-EGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
H+ +L + +I++KCP ITT+Y +I +++ L V F P H PE I N+HGNE IGRE + A+ LCN + D+ I +L+ S IH L SMNPDG+ L G +N DLN DFPDL + F+ +L+K+ DHL + E R ET+ W L++P+VL N H LV NY + ++D+ K Y+ +PDD +R++ + H M K C + G+ W SV G DF+YL+TN M L LSC++ + + W + S+ Y + H GVKG+V D G I AV+ N T++ P + + T GD+YR+L G Y I+V+ +GY A + V+N + SA V++F L
Sbjct: 41 HNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFY-ELQKIGVPKFDHLLS---LFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTGEPIKRAVVWIRNGTETVP--VKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFAL 446
BLAST of carboxypeptidase E vs. Ensembl Celegans
Match: cpd-2 (CarboxyPeptidase D family [Source:UniProtKB/TrEMBL;Acc:Q22825]) HSP 1 Score: 160.999 bits (406), Expect = 1.567e-43 Identity = 115/417 (27.58%), Postives = 192/417 (46.04%), Query Frame = 1
Query: 61 LVSTVAVYCFQLNKQHSN-EELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFG-EGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV-YNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVP----NALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEE-GNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDK 1287
L T+ + LN H N L D + +H+K PN+T +Y +++ L+V V +YP H IPEF +++N+HGNE+ GR F + +A L Y + +I +L+ S RIH + SMNPDGY ++ G G N +DLN +FP +F E Q ET+ MNW +P+ L NLH T + NY + + ++ Y P+PD+ ++ + + H M + RC L + N + G+ W V G D++YL+TN + ++C++ +++ W + +LL + +H + G+V D + G IVNA + D +++ + GE G+++R+ G Y + Y P + V D+
Sbjct: 43 LRDTIGPFRDPLNFSHMNYSTLTDHIHNLHRKFPNLTHIY-----SAGQSVQGRELWVLVVSRYPIEHRKLIPEFKYVANMHGNEVTGRVFLVSLAHTLLENY-NSNLWIRQLVDSTRIHLMPSMNPDGYEHASEGDQAGVTGRQNANGKDLNRNFPSRFPNYFPTSE--------------------IQPETIAIMNWTRQIPFALSANLHGGTTLVNYPFDDFPTRTRQSHYAPSPDNALFVRLAYTYARGHERMWKKGPRCLDDDLNISVDPQNGIINGADWYIVSGGMQDWNYLNTNCFEVTVEMNCEKFPQTKKLRYLWEENKYALLKFIDLIHGAIHGLVIDADTGEGIVNATVS----IDERAKIVVSY---GE-GEFWRLANMGKYDLTFDHSDYYPVTQTVHVTPQDR 425
BLAST of carboxypeptidase E vs. Ensembl Celegans
Match: cpd-2 (CarboxyPeptidase D family [Source:UniProtKB/TrEMBL;Acc:Q22825]) HSP 1 Score: 160.999 bits (406), Expect = 1.567e-43 Identity = 115/417 (27.58%), Postives = 192/417 (46.04%), Query Frame = 1
Query: 61 LVSTVAVYCFQLNKQHSN-EELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFG-EGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV-YNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVP----NALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEE-GNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDK 1287
L T+ + LN H N L D + +H+K PN+T +Y +++ L+V V +YP H IPEF +++N+HGNE+ GR F + +A L Y + +I +L+ S RIH + SMNPDGY ++ G G N +DLN +FP +F E Q ET+ MNW +P+ L NLH T + NY + + ++ Y P+PD+ ++ + + H M + RC L + N + G+ W V G D++YL+TN + ++C++ +++ W + +LL + +H + G+V D + G IVNA + D +++ + GE G+++R+ G Y + Y P + V D+
Sbjct: 43 LRDTIGPFRDPLNFSHMNYSTLTDHIHNLHRKFPNLTHIY-----SAGQSVQGRELWVLVVSRYPIEHRKLIPEFKYVANMHGNEVTGRVFLVSLAHTLLENY-NSNLWIRQLVDSTRIHLMPSMNPDGYEHASEGDQAGVTGRQNANGKDLNRNFPSRFPNYFPTSE--------------------IQPETIAIMNWTRQIPFALSANLHGGTTLVNYPFDDFPTRTRQSHYAPSPDNALFVRLAYTYARGHERMWKKGPRCLDDDLNISVDPQNGIINGADWYIVSGGMQDWNYLNTNCFEVTVEMNCEKFPQTKKLRYLWEENKYALLKFIDLIHGAIHGLVIDADTGEGIVNATVS----IDERAKIVVSY---GE-GEFWRLANMGKYDLTFDHSDYYPVTQTVHVTPQDR 425
BLAST of carboxypeptidase E vs. Ensembl Fly
Match: svr (gene:FBgn0004648 transcript:FBtr0290016) HSP 1 Score: 172.17 bits (435), Expect = 1.134e-45 Identity = 112/404 (27.72%), Postives = 185/404 (45.79%), Query Frame = 1
Query: 142 IHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-------------RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW-LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
I P++T +Y I K++ L+V P H G+PEF +++N+HGNE++G+E +++ Y+ +Y D+ ITKL+ R+HFL SMNPDGY + D G G G N DLN +FPD GT+ F K+ + E MNW L++P+VL NLH +LV NY + + + + R NPT D+ +++++ + HP M + C + + P+ + G+ W SV G D++Y+ + + + C + A + +W LL + QVH G+ G V G I AV++ S + GDY+++ +PG + + V Y P +V ++ F ++
Sbjct: 467 ISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTG-GVGRANAHGIDLNRNFPDQYGTDRFNKVT---------------------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQP-CELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQV--------FGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRM 833 HSP 2 Score: 158.303 bits (399), Expect = 4.494e-41 Identity = 115/413 (27.85%), Postives = 189/413 (45.76%), Query Frame = 1
Query: 112 NEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGI---PEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQ------DLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP-TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK-PAIRCFKVDNLDKFSAKVIDFEL 1317
NEE+ D+ ++ K P++ Y I K++ +Y G P ++N+ G+E +GR+ + MA+YL Y + D + L+ IHFL + NPDG+ + G E NY + DLN DFPD +LE + L + + Q ET +NW+++ P+VL N H +V +Y Y SL + TPDD +++ + + HP M++ C + + G+ W + G DF+Y +N + LSC + + + W+ + SLL RQ H+G+KG+V D G I +A + L + + +RT + G+Y+R+L PG Y++ S GY+ A + +V N D A +DF+L
Sbjct: 38 NEEIGDLFSQLAKDYPDLAQTY-----TIGKSLEDRPIYALALSAPTGESKNGDLLRPMVKLVANIQGDEAVGRQMVLYMAEYLATHY-DGDPKVQALLNLTEIHFLPTCNPDGFAKAKE--GNCESLPNYVGRGNAANIDLNRDFPD----------RLEQSHVHQLRAQSR------QPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN-NCNDSF---SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEE-------KPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTN-DNQEALRLDFKL 414
BLAST of carboxypeptidase E vs. Ensembl Fly
Match: svr (gene:FBgn0004648 transcript:FBtr0290017) HSP 1 Score: 172.17 bits (435), Expect = 1.203e-45 Identity = 112/404 (27.72%), Postives = 185/404 (45.79%), Query Frame = 1
Query: 142 IHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-------------RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW-LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
I P++T +Y I K++ L+V P H G+PEF +++N+HGNE++G+E +++ Y+ +Y D+ ITKL+ R+HFL SMNPDGY + D G G G N DLN +FPD GT+ F K+ + E MNW L++P+VL NLH +LV NY + + + + R NPT D+ +++++ + HP M + C + + P+ + G+ W SV G D++Y+ + + + C + A + +W LL + QVH G+ G V G I AV++ S + GDY+++ +PG + + V Y P +V ++ F ++
Sbjct: 322 ISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTG-GVGRANAHGIDLNRNFPDQYGTDRFNKVT---------------------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQP-CELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQV--------FGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRM 688 HSP 2 Score: 118.242 bits (295), Expect = 9.918e-28 Identity = 81/281 (28.83%), Postives = 131/281 (46.62%), Query Frame = 1
Query: 481 GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP-TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK-PAIRCFKVDNLDKFSAKVIDFEL 1317
G N DLN DFPD +LE + L + + Q ET +NW+++ P+VL N H +V +Y Y SL + TPDD +++ + + HP M++ C + + G+ W + G DF+Y +N + LSC + + + W+ + SLL RQ H+G+KG+V D G I +A + L + + +RT + G+Y+R+L PG Y++ S GY+ A + +V N D A +DF+L
Sbjct: 17 GRGNAANIDLNRDFPD----------RLEQSHVHQLRAQSR------QPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN-NCNDSF---SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEE-------KPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTN-DNQEALRLDFKL 269
BLAST of carboxypeptidase E vs. Ensembl Fly
Match: svr (gene:FBgn0004648 transcript:FBtr0070084) HSP 1 Score: 172.17 bits (435), Expect = 1.211e-45 Identity = 112/404 (27.72%), Postives = 185/404 (45.79%), Query Frame = 1
Query: 142 IHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-------------RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW-LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
I P++T +Y I K++ L+V P H G+PEF +++N+HGNE++G+E +++ Y+ +Y D+ ITKL+ R+HFL SMNPDGY + D G G G N DLN +FPD GT+ F K+ + E MNW L++P+VL NLH +LV NY + + + + R NPT D+ +++++ + HP M + C + + P+ + G+ W SV G D++Y+ + + + C + A + +W LL + QVH G+ G V G I AV++ S + GDY+++ +PG + + V Y P +V ++ F ++
Sbjct: 467 ISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTG-GVGRANAHGIDLNRNFPDQYGTDRFNKVT---------------------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQ-PCELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQV--------FGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRM 833 HSP 2 Score: 158.303 bits (399), Expect = 4.454e-41 Identity = 115/413 (27.85%), Postives = 189/413 (45.76%), Query Frame = 1
Query: 112 NEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGI---PEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQ------DLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP-TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK-PAIRCFKVDNLDKFSAKVIDFEL 1317
NEE+ D+ ++ K P++ Y I K++ +Y G P ++N+ G+E +GR+ + MA+YL Y + D + L+ IHFL + NPDG+ + G E NY + DLN DFPD +LE + L + + Q ET +NW+++ P+VL N H +V +Y Y SL + TPDD +++ + + HP M++ C + + G+ W + G DF+Y +N + LSC + + + W+ + SLL RQ H+G+KG+V D G I +A + L + + +RT + G+Y+R+L PG Y++ S GY+ A + +V N D A +DF+L
Sbjct: 38 NEEIGDLFSQLAKDYPDLAQTY-----TIGKSLEDRPIYALALSAPTGESKNGDLLRPMVKLVANIQGDEAVGRQMVLYMAEYLATHY-DGDPKVQALLNLTEIHFLPTCNPDGFAKAKE--GNCESLPNYVGRGNAANIDLNRDFPD----------RLEQSHVHQLRAQSR------QPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN-NCNDSF---SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEE-------KPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTN-DNQEALRLDFKL 414
BLAST of carboxypeptidase E vs. Ensembl Fly
Match: svr (gene:FBgn0004648 transcript:FBtr0344739) HSP 1 Score: 171.785 bits (434), Expect = 1.282e-45 Identity = 112/404 (27.72%), Postives = 185/404 (45.79%), Query Frame = 1
Query: 142 IHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-------------RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW-LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
I P++T +Y I K++ L+V P H G+PEF +++N+HGNE++G+E +++ Y+ +Y D+ ITKL+ R+HFL SMNPDGY + D G G G N DLN +FPD GT+ F K+ + E MNW L++P+VL NLH +LV NY + + + + R NPT D+ +++++ + HP M + C + + P+ + G+ W SV G D++Y+ + + + C + A + +W LL + QVH G+ G V G I AV++ S + GDY+++ +PG + + V Y P +V ++ F ++
Sbjct: 469 ISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTG-GVGRANAHGIDLNRNFPDQYGTDRFNKVT---------------------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQP-CELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQV--------FGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRM 835 HSP 2 Score: 163.696 bits (413), Expect = 6.948e-43 Identity = 116/411 (28.22%), Postives = 192/411 (46.72%), Query Frame = 1
Query: 109 SNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQ------DLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP-TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK-PAIRCFKVDNLDKFSAKVIDFEL 1317
S E+L D+ + K PN +++L +++ L + P +I+N+HG+E +GR+ + MA YL + ER + +L+ S I+ + +MNPDGY L + G E NY + DLN DFPD +LE + L + + Q ET +NW+++ P+VL N H +V +Y Y SL + TPDD +++ + + HP M++ C + + G+ W + G DF+Y +N + LSC + + + W+ + SLL RQ H+G+KG+V D G I +A + L + + +RT + G+Y+R+L PG Y++ S GY+ A + +V N D A +DF+L
Sbjct: 42 SQEQLEDLFAGLEKAYPNQAKVHFL-----GRSLEGRNLLALQISRNTRSRNLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNH-ERISDLGQLVNSTDIYLVPTMNPDGYALSQE--GNCESLPNYVGRGNAANIDLNRDFPD----------RLEQSHVHQLRAQSR------QPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN-NCNDSF---SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEE-------KPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTN-DNQEALRLDFKL 416
BLAST of carboxypeptidase E vs. Ensembl Fly
Match: svr (gene:FBgn0004648 transcript:FBtr0070087) HSP 1 Score: 171.785 bits (434), Expect = 1.282e-45 Identity = 112/404 (27.72%), Postives = 185/404 (45.79%), Query Frame = 1
Query: 142 IHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-------------RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW-LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
I P++T +Y I K++ L+V P H G+PEF +++N+HGNE++G+E +++ Y+ +Y D+ ITKL+ R+HFL SMNPDGY + D G G G N DLN +FPD GT+ F K+ + E MNW L++P+VL NLH +LV NY + + + + R NPT D+ +++++ + HP M + C + + P+ + G+ W SV G D++Y+ + + + C + A + +W LL + QVH G+ G V G I AV++ S + GDY+++ +PG + + V Y P +V ++ F ++
Sbjct: 469 ISSSYPSLTRLY-----SIGKSVQGRDLWVLEIFATPGSHVPGVPEFKYVANMHGNEVVGKELLLILTKYMLERY-GNDDRITKLVNGTRMHFLYSMNPDGYEISIEGDRTG-GVGRANAHGIDLNRNFPDQYGTDRFNKVT---------------------EPEVAAVMNWTLSLPFVLSANLHGGSLVANYPFDDNENDFNDPFMRLRNSSINGRKPNPTEDNALFKHLAGIYSNAHPTMYLGQP-CELFQNEFFPDGITNGAQWYSVTGGMQDWNYVRAGCLELTIEMGCDKFPKAAELSRYWEDHREPLLQFIEQVHCGIHGFVHSTIGTPIAGAVVRLDGANHSTYSQV--------FGDYWKLALPGRHNLTVLGDNYAPLRMEVEVPDVHPFEMRM 835 HSP 2 Score: 163.696 bits (413), Expect = 6.948e-43 Identity = 116/411 (28.22%), Postives = 192/411 (46.72%), Query Frame = 1
Query: 109 SNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQ------DLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP-TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK-PAIRCFKVDNLDKFSAKVIDFEL 1317
S E+L D+ + K PN +++L +++ L + P +I+N+HG+E +GR+ + MA YL + ER + +L+ S I+ + +MNPDGY L + G E NY + DLN DFPD +LE + L + + Q ET +NW+++ P+VL N H +V +Y Y SL + TPDD +++ + + HP M++ C + + G+ W + G DF+Y +N + LSC + + + W+ + SLL RQ H+G+KG+V D G I +A + L + + +RT + G+Y+R+L PG Y++ S GY+ A + +V N D A +DF+L
Sbjct: 42 SQEQLEDLFAGLEKAYPNQAKVHFL-----GRSLEGRNLLALQISRNTRSRNLLTPPVKYIANMHGDETVGRQLLVYMAQYLLGNH-ERISDLGQLVNSTDIYLVPTMNPDGYALSQE--GNCESLPNYVGRGNAANIDLNRDFPD----------RLEQSHVHQLRAQSR------QPETAALVNWIVSKPFVLSANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGN-NCNDSF---SGGITNGAHWYELSGGMQDFNYAFSNCFELTIELSCCKYPAASTLPQEWQRNKASLLQLLRQAHIGIKGLVTDASGFPIADANVYVAGLEE-------KPMRTSKRGEYWRLLTPGLYSVHASAFGYQTSAPQQVRVTN-DNQEALRLDFKL 416
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Match: cpn1 (carboxypeptidase N, polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9116]) HSP 1 Score: 225.328 bits (573), Expect = 6.913e-68 Identity = 141/417 (33.81%), Postives = 205/417 (49.16%), Query Frame = 1
Query: 46 LVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLD---QYKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
L+L + S FQ H EE+V + + +CP IT +Y I ++ LYV F P H PEF ++ N+HGNE++GRE I ++ +LC +Y +E IT+LI+ RIH L SMNPDGY + + G+ G N DLN +FPDL + EK HN +H E + + ETL + W+ +VL NLH +V NY + +S + + K Y+ T DD I+R + + H M K W C Y+ + G++W S+ G DF+YL TN L LSC + + W + +L+ Y QVH G+KG+V DE N I NAVI ++ + +G LGDY+R+L+PG Y + S GY+P+ V
Sbjct: 13 LLLGLEASLTGASDFQ---HHGYEEMVRALFAVQSECPYITRIY-----SIGRSTEGRHLYVLEFSDNPGIHETLEPEFKYVGNMHGNEVLGRELLIYLSQFLCEEYRAGNERITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSKEVDLNRNFPDLNALMY-YYEK--HNGQNHHLPLPDNWELQVEPETLAVIKWMQNYNFVLSANLHGGAVVANYPFDKSREPRIRGKTTYSATTDDKIFRKLAKTYSYAHSWMHKGW--NCGDYF---DEGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPATALANEWLANREALVSYMEQVHHGIKGMVYDENNNAISNAVISVAGISHD--------ITSGTLGDYFRLLLPGTYTVTASAPGYQPSTSTVTV 405
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Match: cpn1 (carboxypeptidase N, polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9116]) HSP 1 Score: 224.557 bits (571), Expect = 3.048e-66 Identity = 141/417 (33.81%), Postives = 205/417 (49.16%), Query Frame = 1
Query: 46 LVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLD---QYKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
L+L + S FQ H EE+V + + +CP IT +Y I ++ LYV F P H PEF ++ N+HGNE++GRE I ++ +LC +Y +E IT+LI+ RIH L SMNPDGY + + G+ G N DLN +FPDL + EK HN +H E + + ETL + W+ +VL NLH +V NY + +S + + K Y+ T DD I+R + + H M K W C Y+ + G++W S+ G DF+YL TN L LSC + + W + +L+ Y QVH G+KG+V DE N I NAVI ++ + +G LGDY+R+L+PG Y + S GY+P+ V
Sbjct: 145 LLLGLEASLTGASDFQ---HHGYEEMVRALFAVQSECPYITRIY-----SIGRSTEGRHLYVLEFSDNPGIHETLEPEFKYVGNMHGNEVLGRELLIYLSQFLCEEYRAGNERITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSKEVDLNRNFPDLNALMY-YYEK--HNGQNHHLPLPDNWELQVEPETLAVIKWMQNYNFVLSANLHGGAVVANYPFDKSREPRIRGKTTYSATTDDKIFRKLAKTYSYAHSWMHKGW--NCGDYF---DEGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPATALANEWLANREALVSYMEQVHHGIKGMVYDENNNAISNAVISVAGISHD--------ITSGTLGDYFRLLLPGTYTVTASAPGYQPSTSTVTV 537
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Match: cpe (carboxypeptidase E [Source:ZFIN;Acc:ZDB-GENE-090313-68]) HSP 1 Score: 213.772 bits (543), Expect = 1.858e-63 Identity = 138/426 (32.39%), Postives = 217/426 (50.94%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLN---KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGST----WLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
FC VL++ +S+V + + H EE+ ++ + +CP+IT +Y + ++ L V P H G PEF +I N+HGNE +GRE I +A YLCN+Y E ++ I LI+S RIH + SMNPDG+ G + G +N DLN +FPDL + + + E +HL KK +++ K ET ++W++ +P+VL NLH +V NY Y ++ Y+ +PDD +++ + + +P M + R P ++ ++G T W SV G DF+YLS+N L LSC + +++ +W + SL+ Y QVH GV G VRD +GN I NA + +V D + + T + GDY+R+L PG+Y + S GY ++ V
Sbjct: 6 FCGAVLMLALSSVKEAEGENGISFEYHRYEEMRKSLVSVWLQCPSITRIYT-----VGESFEGRELLVLEMSDNPGIHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQEGNDTIIDLIHSTRIHIMPSMNPDGFEKAASQPGEMKDWFVGRSNAQGIDLNRNFPDLDRIVY--MNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYSASPDDLVFKSLAKAYSIYNPVMSDTN-RPPCRKNDDDSSFKEGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPEDSLKQYWDQNRNSLVNYIEQVHRGVSGFVRDLQGNPISNASV-SVEGIDHD-------ITTAKDGDYWRLLAPGNYKVSASAPGYLTVVKKVAV 415
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Match: cpe (carboxypeptidase E [Source:ZFIN;Acc:ZDB-GENE-090313-68]) HSP 1 Score: 213.772 bits (543), Expect = 1.858e-63 Identity = 138/426 (32.39%), Postives = 217/426 (50.94%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLN---KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGST----WLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
FC VL++ +S+V + + H EE+ ++ + +CP+IT +Y + ++ L V P H G PEF +I N+HGNE +GRE I +A YLCN+Y E ++ I LI+S RIH + SMNPDG+ G + G +N DLN +FPDL + + + E +HL KK +++ K ET ++W++ +P+VL NLH +V NY Y ++ Y+ +PDD +++ + + +P M + R P ++ ++G T W SV G DF+YLS+N L LSC + +++ +W + SL+ Y QVH GV G VRD +GN I NA + +V D + + T + GDY+R+L PG+Y + S GY ++ V
Sbjct: 6 FCGAVLMLALSSVKEAEGENGISFEYHRYEEMRKSLVSVWLQCPSITRIYT-----VGESFEGRELLVLEMSDNPGIHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQEGNDTIIDLIHSTRIHIMPSMNPDGFEKAASQPGEMKDWFVGRSNAQGIDLNRNFPDLDRIVY--MNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYSASPDDLVFKSLAKAYSIYNPVMSDTN-RPPCRKNDDDSSFKEGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPEDSLKQYWDQNRNSLVNYIEQVHRGVSGFVRDLQGNPISNASV-SVEGIDHD-------ITTAKDGDYWRLLAPGNYKVSASAPGYLTVVKKVAV 415
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Match: cpxm1b (carboxypeptidase X (M14 family), member 1b [Source:ZFIN;Acc:ZDB-GENE-141212-305]) HSP 1 Score: 216.083 bits (549), Expect = 5.173e-61 Identity = 128/407 (31.45%), Postives = 214/407 (52.58%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFK--KLEKLEHNMTDHLFTRKKFLEKKYQR-------ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEW-RVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNR-IVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVD 1275
+ H+ +E+ +M +++ CP+IT +Y I K+ M +LYV P +H G PEF +++ +HGNE++GRE + + ++C +Y ++ I L+ RIH L +MNPDGY + +++ G+ G +Y D+NH+F DL T + +L+ + + +H F + ++Y ET ++W+ T+P+VL NLH LV Y + + D R PT DD+ +R++ + + + + M R C N + G+ W +V +DFSYL TN + LSC + + + W+ + SLL Y QVH G+KGV+RD++ I +A+IK + I +R+ GD++R+L PGDY I V+ +GY PA R +V+
Sbjct: 503 RHHNYKEMRKLMKSVNEMCPDITRIY-----SIGKSYMGLKLYVMEISDNPGKHELGEPEFRYVAGMHGNEVLGRELQLNLMQFICQEYRRGNQRILHLVKETRIHLLPAMNPDGYEMAYKKGSELAGWALGRYSYEGIDMNHNFADLNTVMWDAIELQTDKSKLINHYFP----IPEQYTSEDAWVAPETRAVISWMQTIPFVLSANLHGGELVVTYPFDMTRDWAPREQTPTADDSFFRWLATVYASTNHVMSNPDRRPCHNEDFLRHNNIINGANWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHASELPTEWQNNKESLLVYMEQVHRGIKGVIRDKDTEAGIADAIIKVDD--------IDHHIRSAADGDFWRLLNPGDYDITVTAEGYFPASRSCRVE 892
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Match: cpe (carboxypeptidase E [Source:NCBI gene;Acc:100127580]) HSP 1 Score: 211.846 bits (538), Expect = 2.004e-62 Identity = 140/452 (30.97%), Postives = 224/452 (49.56%), Query Frame = 1
Query: 25 LVMNFCILVLLILVSTVAVYCFQLNKQ--------HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWR---VRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV-IDFELPS 1323
+++ C+LVLL S++A +L+++ H E+ D ++ + +CP+I+ +Y + ++ L V P H G PEF ++ N+HGNE +GRE + A YLCN+Y +E I LI++ RIH + S+NPDG+ D+ + G +N DLN +FPDL + L + E +HL KK +++ K ET+ ++W++ +P+VL NLH LV NY Y ++ Y+ PDD I++ + + + +P M + R + G+ W SV G DF+YLS+N + L C + ++ +W + SL+ Y QVH GV G V+D G I NA I +V+ D + + + + GDY+R+L PG+Y I S GY + V +S V IDF+L S
Sbjct: 11 VLLGACMLVLLGCSSSLA-RGRRLSREPGDISYEYHRYPEMRDALVAVWLQCPSISRIYT-----VGRSFEGRELLVIEISDNPGEHEPGEPEFKYVGNMHGNEAVGRELLLYFAQYLCNEYQRENETIVNLIHNTRIHIMPSLNPDGFEKAAQQPGDIKDWFVGRSNAQGIDLNRNFPDLDRIVY--LNEREGGTNNHLLQNLKKSVDENAKLAPETVAVIHWIMDIPFVLSANLHGGDLVANYPYDKTRSGSTHEYSACPDDGIFQSLARSYSSLNPTMSDPDRKPCRKSDDDSSFIDGTTNGAAWYSVPGGMQDFNYLSSNCFEITVELGCDKFPPEEMLKSYWEENKDSLVNYLMQVHRGVTGFVKDHHGFPIANATI-SVDGIDHD-------VTSAKDGDYWRLLAPGNYKITASAPGYLAVAKKVAV----PYSPAVKIDFDLES 442
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Match: gli1 (GLI family zinc finger 1 [Source:Xenbase;Acc:XB-GENE-482644]) HSP 1 Score: 211.46 bits (537), Expect = 2.088e-62 Identity = 134/412 (32.52%), Postives = 201/412 (48.79%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDV----YGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKR-----VYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
+ L L +L A F H ++LV + + +CP IT +Y I +++ LYV F P H PEF ++ N+HGNE++GRE I +A++LC +Y +E +T+LI + RIH L SMNPDGY + D G+ G NY DLN +FPDL T + EK + +H + + ET + WL +VL NLH +V NY Y +S + R Y+ TPDD +++ + + H M C ++ + G++W S+ G DF+YL TN L LSC + ++ W + +LL Y +VH G+KG++ DE GN I NAVI + + +G GDY+R+L+PG Y + S +GY
Sbjct: 6 WSFLQLFLLCEVAASLSF---FHHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYN-EK--YGGPNHHLPLPDNWMAQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWMHTG-YNCDDFFY---EGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNGIANAVISISEIAHD--------VTSGIGGDYFRLLLPGTYEVTASAEGY 394
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Match: gli1 (GLI family zinc finger 1 [Source:Xenbase;Acc:XB-GENE-482644]) HSP 1 Score: 211.46 bits (537), Expect = 2.172e-62 Identity = 135/412 (32.77%), Postives = 201/412 (48.79%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDV----YGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKR-----VYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
+ L L +L A F H ++LV + + +CP IT +Y I +++ LYV F P H PEF ++ N+HGNE++GRE I +A++LC +Y +E +T+LI + RIH L SMNPDGY + D G+ G NY DLN +FPDL T + EK + +H + + ET + WL +VL NLH +V NY Y +S + R Y+ TPDD +++ + + H M C ++ + G++W S+ G DF+YL TN L LSC + ++ W + +LL Y +VH G+KG++ DE GN I NAVI I + +G GDY+R+L+PG Y + S +GY
Sbjct: 6 WSFLQLFLLCEVAASLSF---FHHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYN-EK--YGGPNHHLPLPDNWMAQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWMHT-GYNCDDFFY---EGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNGIANAVISISE--------IAHDVTSGIGGDYFRLLLPGTYEVTASAEGY 394
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Match: gli1 (GLI family zinc finger 1 [Source:Xenbase;Acc:XB-GENE-482644]) HSP 1 Score: 210.305 bits (534), Expect = 2.652e-62 Identity = 130/390 (33.33%), Postives = 194/390 (49.74%), Query Frame = 1
Query: 103 QHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDV----YGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKR-----VYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
H ++LV + + +CP IT +Y I +++ LYV F P H PEF ++ N+HGNE++GRE I +A++LC +Y +E +T+LI + RIH L SMNPDGY + D G+ G NY DLN +FPDL T + EK + +H + + ET + WL +VL NLH +V NY Y +S + R Y+ TPDD +++ + + H M C ++ + G++W S+ G DF+YL TN L LSC + ++ W + +LL Y +VH G+KG++ DE GN I NAVI I + +G GDY+R+L+PG Y + S +GY
Sbjct: 14 HHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYN-EK--YGGPNHHLPLPDNWMAQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWMHTG-YNCDDFFY---EGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNGIANAVISISE--------IAHDVTSGIGGDYFRLLLPGTYEVTASAEGY 383
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Match: gli1 (GLI family zinc finger 1 [Source:Xenbase;Acc:XB-GENE-482644]) HSP 1 Score: 210.305 bits (534), Expect = 3.518e-62 Identity = 130/390 (33.33%), Postives = 194/390 (49.74%), Query Frame = 1
Query: 103 QHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDV----YGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKR-----VYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
H ++LV + + +CP IT +Y I +++ LYV F P H PEF ++ N+HGNE++GRE I +A++LC +Y +E +T+LI + RIH L SMNPDGY + D G+ G NY DLN +FPDL T + EK + +H + + ET + WL +VL NLH +V NY Y +S + R Y+ TPDD +++ + + H M C ++ + G++W S+ G DF+YL TN L LSC + ++ W + +LL Y +VH G+KG++ DE GN I NAVI I + +G GDY+R+L+PG Y + S +GY
Sbjct: 24 HHRYDDLVRALYNVQNQCPYITRVY-----SIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYVGNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGYLTGRYNYRQVDLNRNFPDLNTVMYYN-EK--YGGPNHHLPLPDNWMAQVEPETQAMIQWLKNYNFVLSANLHGGAVVANYPYDKSKEIRMRGFTRSTYSSTPDDALFKELAKTYSYAHGWMHTG-YNCDDFFY---EGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEWNGNREALLTYIDKVHQGIKGMITDENGNGIANAVISISE--------IAHDVTSGIGGDYFRLLLPGTYEVTASAEGY 393
BLAST of carboxypeptidase E vs. Ensembl Mouse
Match: Cpn1 (carboxypeptidase N, polypeptide 1 [Source:MGI Symbol;Acc:MGI:2135874]) HSP 1 Score: 232.261 bits (591), Expect = 2.059e-70 Identity = 137/436 (31.42%), Postives = 221/436 (50.69%), Query Frame = 1
Query: 40 CILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ-----YKRVYNPTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
L LL+L V F + H ++LV + K+H +CP+IT +Y +I +++ LYV F YP H PE ++ N+HGNE++GRE + ++++LC ++ R++ I +LI RIH L SMNPDGY + ++ G+ G NN DLN +FPDL T F+ ++ +H + + + ET + W+ ++ +VL N+H +V NY Y +SL+ ++ +PTPDD +++ + + H M + W C Y+ P+ + G++W S+ G DF+YL TN L LSC + +Q W + +L+ + QVH G+KG+V DE N + AVI + + +GE GDY+R+L+PG Y++ GY P V V+DF+L
Sbjct: 7 AFLPLLLLSKFVTPVTF---RHHRYDDLVRTLYKVHNQCPDITRLY-----NIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYY---NSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGW--NCGDYF---PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHD--------VTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTV---GPAGPTVVDFQL 415
BLAST of carboxypeptidase E vs. Ensembl Mouse
Match: Cpe (carboxypeptidase E [Source:MGI Symbol;Acc:MGI:101932]) HSP 1 Score: 211.46 bits (537), Expect = 2.567e-62 Identity = 138/418 (33.01%), Postives = 212/418 (50.72%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG----FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGST----WLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV-IDFELPS 1323
H EL + ++ + +C I+ +Y + ++ L V P H G PEF +I N+HGNE +GRE I +A YLCN+Y + +E I LI+S RIH + S+NPDG+ G + G +N DLN +FPDL + + + E +HL KK +++ K ET ++W++ +P+VL NLH LV NY Y ++ Y+ PDD I++ + + + +P M + R P ++ G+T W SV G DF+YLS+N + LSC++ ++ +W + SL+ Y Q+H GVKG VRD +GN I NA I +V+ D + + + + GDY+R+L PG+Y + S GY + V FS V +DFEL S
Sbjct: 54 HRYPELREALVSVWLQCTAISRIYT-----VGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVY--VNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPN-RPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATI-SVDGIDHD-------VTSAKDGDYWRLLAPGNYKLTASAPGYLAITKKVAV----PFSPAVGVDFELES 451
BLAST of carboxypeptidase E vs. Ensembl Mouse
Match: Cpm (carboxypeptidase M [Source:MGI Symbol;Acc:MGI:1917824]) HSP 1 Score: 197.208 bits (500), Expect = 2.897e-57 Identity = 134/435 (30.80%), Postives = 214/435 (49.20%), Query Frame = 1
Query: 31 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP--TPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDK-FSAKVIDFELP 1320
M+ L L +L+ VA F+ + Q E + + + N +++ +L I K++ L+V V G+ P H GIPEF +++N+HG+E +GRE + + DYL + Y +D IT LI S RIH + SMNPDG+ + + D Y + G NY DLN +FPD E+N Q ETL M WL T +VL NLH LV +Y + + + + TPDD++++++ + +R+P M + +C + PN + G +W ++ G D++Y+ L LSC + + W + SL+ Y +QVH+GVKG V D+ G + N +++ + P+ RT +LG+YY +L+PG Y I V+ G+ + + + FSA DF LP
Sbjct: 1 MDRARLWLGLLLPVVAALDFRYHHQEGMEAFLKSVAQ------NYSSITHLH--SIGKSVRGRNLWVLVVGQTPKEHRVGIPEFKYVANMHGDETVGRELLLHLIDYLVSSY-RKDPEITHLIDSTRIHIMPSMNPDGFEAVQKPDCY-YSNGRENYNNYDLNRNFPD----------AFENNNVTK------------QPETLAIMEWLKTETFVLSANLHGGALVASYPFDNGVQATGTLLSRSLTPDDDVFQHLAYTYASRNPNMTKGD-QCKNKRNF-PNGIINGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPLFWNDNKASLIEYIKQVHLGVKGQVFDQSGAPLPNVIVEVQDRKHICPF------RTNKLGEYYLLLLPGSYVINVTVPGHDSYLTKLTIPGKSQPFSALKKDFHLP 395
BLAST of carboxypeptidase E vs. Ensembl Mouse
Match: Cpxm2 (carboxypeptidase X 2 (M14 family) [Source:MGI Symbol;Acc:MGI:1926006]) HSP 1 Score: 201.445 bits (511), Expect = 2.048e-56 Identity = 120/393 (30.53%), Postives = 202/393 (51.40%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEK--LEHNMTDHLFTRKK-FLEKKY--QRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVR-CPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
K H+ +E+ +M +++ CPNIT +Y +I K+ +LY +P H G PEF +I+ HGNE++GRE +L+ +LC +Y ++ I +L+ RIH L S+NPDGY +++ G+ G + D+N++FPDL + ++ ++ + +H + FL + ET + W+ +P+VL NL LV Y Y +K + + PTPDD+++R++ + + H M + R R C T G++W +V +DFSYL TN ++++ C + + + W + SL+ + QVH G+KG+VRD +G I NAVI + +RT GDY+R+L PG+Y + +G+
Sbjct: 325 KHHNYKEMRQLMKVVNEMCPNITRIY-----NIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLLHFLCQEYSAQNARIVRLVEETRIHILPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNSLLWEAEDQQNAPRKVPNHYIAIPEWFLSENATVATETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDMVRSLWKTQEHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCDKYPHESELPEEWENNRESLIVFMEQVHRGIKGIVRDLQGKGISNAVISVEGVNHD--------IRTASDGDYWRLLNPGEYVVTAKAEGF 704
BLAST of carboxypeptidase E vs. Ensembl Mouse
Match: Cpxm1 (carboxypeptidase X 1 (M14 family) [Source:MGI Symbol;Acc:MGI:1934569]) HSP 1 Score: 199.904 bits (507), Expect = 4.233e-56 Identity = 122/394 (30.96%), Postives = 200/394 (50.76%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEK--LEHNMTDH---LFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQY-KRVYNPTPDDNIYRYIGSRFVARHPEMKEW-RVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGN-RIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGY 1245
+ H+ + + +M +++++CPNIT +Y I K+ +LYV +P H G PE +++ +HGNE +GRE +L+ +LC+++L D +T+L+ RIH L SMNPDGY +++ G+ EG + DLNH+F DL T+ + + + + +H L T ET + W+ +P+VL NLH LV +Y + + + R PTPDD ++R++ + + + M++ R C + + + G+ W +V +DFSYL TN + LSC + + W + +LL Y QV MG+ GVVRD++ I +AVI + + T GDY+R+L PGDY + S +GY
Sbjct: 287 RHHNYKAMRKLMKQVNEQCPNITRIY-----SIGKSHQGLKLYVMEMSDHPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGDPRVTRLLTETRIHLLPSMNPDGYETAYHRGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPDTVPNHHLPLPTYYTLPNATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGINHD--------VTTAWGGDYWRLLTPGDYVVTASAEGY 667
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Match: sp|Q2KJ83|CBPN_BOVIN (Carboxypeptidase N catalytic chain OS=Bos taurus OX=9913 GN=CPN1 PE=2 SV=1) HSP 1 Score: 234.572 bits (597), Expect = 2.650e-70 Identity = 140/437 (32.04%), Postives = 226/437 (51.72%), Query Frame = 1
Query: 40 CILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT-----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ----YKRVYN-PTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
I + L+L VA F + H ++LV ++ K+H +CP+IT +Y I +++ LYV F YP H PE ++ N+HGNE++GRE + ++++LC ++ R++ I +L+ RIH + SMNPDGY + D+ G+ G NN DLN +FPDL T + EK + +H F + + + ET + W+ + +VL NLH +V NY Y +SL ++R N PTPDD +++ + + H M + W C Y+ P+ + G++W S+ G DF+YL TN L LSC + L +Q W + +L+ + QVH G+KG+VRDE N + +AVI + + +G GDY+R+L+PG Y + + G+ P V + K+++F+L
Sbjct: 6 SIFLHLLLFKLVAPVTF---RHHRYDDLVRMLYKVHNECPHITRVY-----SIGRSVKGRHLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRIVRLVEDTRIHIMPSMNPDGYEVAAAAQERDISGYLVGRNNANGVDLNRNFPDLNTYIYYN-EK--NGGPNHHFPLPDNWKSQVEPETQAVIQWIRSFNFVLSANLHGGAVVANYPYDKSLGHRVRGFRRTANTPTPDDKLFQKLAKIYSYAHGWMHQGW--NCGDYF---PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPLQGELQREWLGNREALIQFLEQVHQGIKGMVRDENYNNLADAVISVGGINHD--------VTSGAHGDYFRLLLPGTYTVTATAPGFDPETVSVTVGPAE---PKLVNFQL 415
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Match: sp|Q9JJN5|CBPN_MOUSE (Carboxypeptidase N catalytic chain OS=Mus musculus OX=10090 GN=Cpn1 PE=1 SV=1) HSP 1 Score: 232.261 bits (591), Expect = 1.440e-69 Identity = 137/436 (31.42%), Postives = 221/436 (50.69%), Query Frame = 1
Query: 40 CILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ-----YKRVYNPTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
L LL+L V F + H ++LV + K+H +CP+IT +Y +I +++ LYV F YP H PE ++ N+HGNE++GRE + ++++LC ++ R++ I +LI RIH L SMNPDGY + ++ G+ G NN DLN +FPDL T F+ ++ +H + + + ET + W+ ++ +VL N+H +V NY Y +SL+ ++ +PTPDD +++ + + H M + W C Y+ P+ + G++W S+ G DF+YL TN L LSC + +Q W + +L+ + QVH G+KG+V DE N + AVI + + +GE GDY+R+L+PG Y++ GY P V V+DF+L
Sbjct: 7 AFLPLLLLSKFVTPVTF---RHHRYDDLVRTLYKVHNQCPDITRLY-----NIGRSVKGRYLYVLEFSDYPGIHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNMSGYLVGRNNANGVDLNRNFPDLNTYFYY---NSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGW--NCGDYF---PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENSNNLTGAVISVTGINHD--------VTSGEHGDYFRLLLPGTYSVTAKAPGYDPKTVTVTV---GPAGPTVVDFQL 415
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Match: sp|Q9EQV8|CBPN_RAT (Carboxypeptidase N catalytic chain OS=Rattus norvegicus OX=10116 GN=Cpn1 PE=2 SV=1) HSP 1 Score: 231.491 bits (589), Expect = 3.617e-69 Identity = 136/436 (31.19%), Postives = 221/436 (50.69%), Query Frame = 1
Query: 40 CILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ-----YKRVYNPTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
L LL+L V F + H ++LV + K+H +CP+IT +Y +I +++ LYV F YP H PE ++ N+HGNE++GRE + ++++LC ++ R++ I +LI RIH L SMNPDGY + + G+ G NN DLN +FPDL T F+ ++ +H + + + ET + W+ ++ +VL N+H +V NY Y +SL+ ++ +PTPDD +++ + + H M + W C Y+ P+ + G++W S+ G DF+YL TN L LSC + +Q W + +L+ + QVH G+KG+V DE N + AVI + + +GE GDY+R+L+PG Y++ GY+P V ++DF+L
Sbjct: 7 AFLPLLLLSKFVTPVTF---RHHRYDDLVRTLYKVHNQCPDITRLY-----NIGRSVKGRYLYVLEFSDYPGTHEPLEPEVKYVGNMHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQGPNTSGYLVGRNNANGVDLNRNFPDLNTYFYY---NSKYGGPNHHLPLPDNWKSQVEPETRAVIQWIRSLNFVLSANMHGGAVVANYPYDKSLEHRFRSPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGW--NCGDYF---PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCNKFPRQEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLTGAVISVTGINHD--------VTSGEHGDYFRLLLPGTYSVTAKASGYEPKTVTVTV---GPAGPTLVDFQL 415
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Match: sp|O17754|CBPE_CAEEL (Carboxypeptidase E OS=Caenorhabditis elegans OX=6239 GN=egl-21 PE=1 SV=1) HSP 1 Score: 218.779 bits (556), Expect = 3.365e-64 Identity = 141/417 (33.81%), Postives = 208/417 (49.88%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQR--ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQ--YKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTY---WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDE-EGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
H+ +L + +I++KCP ITT+Y +I +++ L V F P H PE I N+HGNE IGRE + A+ LCN + D+ I +L+ S IH L SMNPDG+ L G +N DLN DFPDL + F+ +L+K+ DHL + E R ET+ W L++P+VL N H LV NY + ++D+ K Y+ +PDD +R++ + H M K C + G+ W SV G DF+YL+TN M L LSC++ + + W + S+ Y + H GVKG+V D G I AV+ N T++ P + + T GD+YR+L G Y I+V+ +GY A + V+N + SA V++F L
Sbjct: 41 HNQAQLEAKLGEINEKCPEITTLY-----EIGQSVEGRPLVVIQFSTTPGEHIPTKPEVKLIGNMHGNEPIGRELLLRFAETLCNGAINNDKEIVQLLNSTSIHILPSMNPDGFELALGTEPAQRQWLTGRSNINGVDLNRDFPDLDSIFY-ELQKIGVPKFDHLLS---LFEDNVDRQPETIAVGQWTLSLPFVLSANFHEGDLVANYPFDAAIDENSQKTAYSASPDDGTFRWLAKSYADNHAHMSKNDHAPCDGTSQDAFARQGGITNGAKWYSVAGGMQDFNYLATNAMEITLELSCEKMPEGSQLPRFWEDNQKSIFEYVWKSHSGVKGMVVDAMTGEPIKRAVVWIRNGTETVP--VKHPVTTWSEGDFYRVLPAGKYEIIVAAEGYDIAAKNVTVENKVRDSALVVNFAL 446
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Match: sp|P37892|CBPE_LOPAM (Carboxypeptidase E OS=Lophius americanus OX=8073 GN=cpe PE=2 SV=1) HSP 1 Score: 218.009 bits (554), Expect = 3.834e-64 Identity = 149/444 (33.56%), Postives = 217/444 (48.87%), Query Frame = 1
Query: 37 FCILVLL-----ILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG----FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTY--WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPS 1323
C +VLL LVS + H EEL ++ + +CP I +Y I ++ L V P H G PEF +I+N+HGNE +GRE I +A YLCN+Y + +E I LI+S RIH + SMNPDG+ G + G +N DLN +FPDL + + E +HL KK +++ K ET ++W++ +P+VL NLH +V NY Y ++ Y+ +PDD I++ + F +P M + R C + + + G W SV G DF+YLS+N L LSC + ++ +W + SL+ Y QVH GVKG VRD +GN I NA I +V D + + T + GDY+R+L G+Y + S GY I+ V + A +DFEL S
Sbjct: 4 ICSIVLLGAAVVSLVSAAGSDSEISFEYHRYEELRKALVSVWLQCPTIARIYT-----IGESFEGRELLVLEMSDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHSTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGVDLNRNFPDLDRIIYTN--EREGGANNHLLQNMKKAVDENTKLAPETKAVIHWIMEIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVIFKSLAKAFSIYNPVMSDPQRPPCRKHDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPNEDTLKTYWEQNRNSLVNYIEQVHRGVKGYVRDLQGNPIFNATI-SVEGIDHD-------ITTAKDGDYWRLLRQGNYKVAASAPGYLTVIKKVAVPH---SPATRVDFELES 429
BLAST of carboxypeptidase E vs. TrEMBL
Match: A0A1S3JWZ2 (carboxypeptidase E OS=Lingula unguis OX=7574 GN=LOC106176829 PE=4 SV=1) HSP 1 Score: 268.085 bits (684), Expect = 7.448e-80 Identity = 165/472 (34.96%), Postives = 243/472 (51.48%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVY------GFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGST----WLSVKNGWHDFSYLSTNLMGNNLFLSCQR----NMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNR-IVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELP-------SEYYYLDPECIRFNLDQTTVHE 1386
C L +++ +V K H+ +E++D M+KIHKKCP IT Y L+ KT+M+ L V P +H G PEF ++ N+HGNE++GRE + + DY+C++Y ++ I KL+ S RIH + SMNPDG+ + T+ + + +G +N DLN +FPDL ++ EK H + + ++K Q ET M M W+ VP+VL NLH LV NY Y +S + Y+ +PDD+ +RY+ + H M + C QKG+T W SV G DF+YL TN L L C + N LP QF W + +L+ + Q H+G+KGV+RD + + I +A +K NLT I + + GDY+R+LIPG Y + V+ GY P +C +V N + AK +DFEL S +DP C N+ V E
Sbjct: 7 LCSLAIVLFGECSSVEL----KHHNYKEMLDYMVKIHKKCPEITRPYVLE----GKTVMNRSLAVLEMSDNPGKHEIGEPEFKYVGNMHGNEVVGRELLLALLDYMCDQYKAGNKTIVKLLESTRIHIMPSMNPDGWEIATESFKKTGKKDWLKGRSNANNVDLNRNFPDLDRIVYRNHEKNNH-IKEKTHDQQK---NPIQPETYMAMEWIQEVPFVLSSNLHGGDLVANYPYDESQSGAPQEYSKSPDDSTFRYLAESYSLWHATMAKPHESCDDMPDNEKFLKQKGTTNGAAWYSVAGGMQDFNYLRTNCFEITLELGCDKYPPENALP---QF-WEDNKDALINFMWQTHIGIKGVIRDAQTKKGIASATVKVHNLTSDAD--INHDITSAHDGDYWRLLIPGSYMVTVTAPGYLPQTKCMEVTNPFRTEAKEVDFELQPLREDAMSVKADVDPSCAHLNMVPNAVME 460
BLAST of carboxypeptidase E vs. TrEMBL
Match: A0A437B9N3 (Uncharacterized protein OS=Chilo suppressalis OX=168631 GN=evm_008283 PE=4 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 9.708e-80 Identity = 156/449 (34.74%), Postives = 234/449 (52.12%), Query Frame = 1
Query: 37 FCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG--FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYK-RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVR---------CPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPE 1347
+ +L L +S A + + K H+NEEL ++ ++H+KCPNIT +Y L + ++ + LYV F P H PE +I N+HGNE++GRE + +A YLC++YL +D I L++S RIH L SMNPDG+ L TD G + G NN DLN +FPDL + F + E+ N +HL L + ET M W++++P+VL +H LV NY Y +S Y+ +PDD +R + + + H +M R TY + G+ W S+K G DF+YL+TN L L C++ + + W + +LL Y + H+G+KG+V D+ G I NA+I VN+T P I + TG GDYYR+L PG Y + ++ GY P R V + + +A V++F L + D E
Sbjct: 4 YVVLAFLFCLSASAEFVW---KHHNNEELPLVLEEVHEKCPNITRVYAL----TEPSVCNVPLYVIEFSDTPGFHQPYKPEVKYIGNIHGNEVLGRELLLGLAHYLCDQYLNQDRRIRALVHSTRIHLLPSMNPDGWQLSTDTGGQDYLIGRNNNHSIDLNRNFPDLDSITF-EFERQGINHNNHLLKDLTRLAAPLEPETRAVMRWIMSIPFVLSAAIHGGDLVANYPYDESRSGAPVSEYSASPDDETFRELALAYASAHADMASVNRRGCHATSADDSATYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEVTLELGCEKYPPESLLAKEWERNREALLSYLWKAHIGIKGIVSDDSG-FIQNAIISVVNITGPIPRPIRHDVTTGAYGDYYRLLTPGHYEVTATRPGYFPVSRVVTVPH-HQAAAHVLNFRLEPTTSWFDDE 442
BLAST of carboxypeptidase E vs. TrEMBL
Match: A0A443S5Z9 (Carboxypeptidase E-like protein (Fragment) OS=Leptotrombidium deliense OX=299467 GN=B4U80_07312 PE=4 SV=1) HSP 1 Score: 264.233 bits (674), Expect = 4.708e-79 Identity = 156/449 (34.74%), Postives = 239/449 (53.23%), Query Frame = 1
Query: 25 LVMNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE---GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWR-VRCPTYWLY-VPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDE-EGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL----PSEYYYLD 1341
+ ++F + ++ +Y F K H N EL +++ KI+ KCPNIT +Y L ++++ L V P H PEF +I+N+HGNE++GRE + +ADYLC +Y + I +L+ R+H L SMNPDG+ L + + G +N DLN DFPDL +E ++ E+ +DHLFTR+ ++ K Q ET +NW+L P+VL NLH LV NY Y ++ D + Y TPDD+ +R++ + +H M + + +C + + G+ W SV G DF+YLS+N L L C++ + ++ W + +LL Y Q H+G+KGVV D G+ I +A+IK NLT I + +G+ G+++R+L PG Y I V K GY+P IR V + K A + +L SEY D
Sbjct: 5 IFISFLLFAVIYQTRGEQIYSF---KHHDNNELNEVLQKINAKCPNITRIYELS----ERSVKGWPLTVIELSDNPGTHEFLEPEFRYIANMHGNEVLGRELLLKLADYLCEEYKRNNVEIQRLLNLTRVHILPSMNPDGWDLASTKQAGDDWLTGRSNANGVDLNRDFPDLDSEAYRTSER-----SDHLFTREA-IDHKLQPETRAIINWILNTPFVLSANLHGGALVANYPYDETPDGSQHRYTATPDDDTFRHLAQIYAKKHKTMTQPKHEKCDDDDEFGKQGGITNGAAWYSVAGGLQDFNYLSSNDFEITLELGCEKYPPESKLEKEWENNKDALLEYMWQSHIGLKGVVMDAMTGDLIADALIKVKNLTSGRNQYIDHDIHSGKTGEFWRLLTPGVYEITVVKDGYEPLIRTHTVTDNSKSEATRLKLKLQPIASSEYKRAD 440
BLAST of carboxypeptidase E vs. TrEMBL
Match: A0A4C1SPZ9 (Carboxypeptidase E OS=Eumeta variegata OX=151549 GN=CPE PE=4 SV=1) HSP 1 Score: 263.077 bits (671), Expect = 1.248e-78 Identity = 160/451 (35.48%), Postives = 235/451 (52.11%), Query Frame = 1
Query: 31 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG--FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV-YNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPT--------YWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPE 1347
MNF ++ L VA C + K H+NEEL ++ +IH+KCPNIT +Y L + +++ LYV F P H PE +++N+HGNE++GRE + +A+Y C YL D+ I LI++ RIH L SMNPDG+ L TD G + G +N DLN +FPDL F +LE+ N +HL L + ET M W++ +P+VL +H LV NY Y +S Y+ +PDD+ +R + + H +M + R C + Y + G+ W S+K G DF+YL+TN L L C + + + W+ + +L+ Y +VH G+KGVV D+ G + NA+I VN+T P I+ + TG GDYYR+L PG Y + S GY P R V + SA +++FEL + D E
Sbjct: 1 MNFHFILFGSLF--VAASCEFVWKHHNNEELPLVLEEIHRKCPNITRVYALS----EPSVLGVPLYVIEFSDKPGFHQPYKPEAKYVANIHGNEVLGRELLLGLANYFCEAYLNNDQRIGLLIHTTRIHLLPSMNPDGWQLATDTGGQDYLLGRSNNHSVDLNRNFPDLDAITF-ELEREGINHNNHLLRDITRLAAPLEPETRAVMRWIMQIPFVLSAAMHGGDLVANYPYDESRSGAPVAEYSASPDDDTFRDLAMTYATAHADMASKTRPGCHSTSADDSSLYNFGKQGGVTNGAAWYSLKGGMQDFNYLATNAFEITLELGCDKYPPASALPREWQRNKEALIQYLWKVHSGIKGVVTDDSG-FLQNAIISVVNITGHIPRPIIHDVTTGLYGDYYRLLTPGHYEVTASHPGYFPISRIATVPYGQQTSAVILNFELEPTSSWFDEE 443
BLAST of carboxypeptidase E vs. TrEMBL
Match: A0A1S5QN46 (Carboxypeptidase E OS=Tityus serrulatus OX=6887 PE=2 SV=1) HSP 1 Score: 261.922 bits (668), Expect = 2.967e-78 Identity = 141/413 (34.14%), Postives = 225/413 (54.48%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFG--EGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAV-IKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSE 1326
K H+NEEL+ +++ +H KCPNIT +Y L + +++ L V K P +H PEF ++ N+HGNE++GRE + ++ YLCN+Y++ +E + +L+ RIH L S+NPDG+ + + G +G N DLN DFPDL ++ + ++ +HLF+ K ++ K+Q ETL M W+L P+VL NLH LV N+ Y +S + Y TPDD+ +R++ S + H M + + C + G+ W SV G DF+YL +N + L C + + ++ W + +L+ + Q H+G+KGVV+D E ++ +++V IKTVN+TD + +I + + G+Y+R+L PG Y I GYK V N A +DF L E
Sbjct: 28 KHHNNEELLQVLLDVHNKCPNITRLYELSH----RSVRGQPLAVLEITKNPGKHEFLKPEFKYVGNMHGNEVLGREMLLALSSYLCNEYIKGNEDVQRLVNMTRIHILPSLNPDGWEMASKTNGDSWLKGRGNANEVDLNRDFPDLNQIVYEHNDDIDDRFNNHLFS-KDAVDHKFQPETLAAMKWILKNPFVLSANLHGGALVANFPYDESFHHSSQEYTATPDDDTFRHLASSYSKAHKTMAADKSIACNGDDFSHQGGITNGAAWYSVAGGMQDFNYLGSNDFEITVELGCNKYPPASELEKEWFNNKDALINFIWQSHIGIKGVVKDAETDQPLSSVYIKTVNITDDKHRLINHDVTSVINGEYWRLLTPGKYEITALTPGYKAETETITVSNPPFQEAIRLDFALEPE 435
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Match: cpn1 (carboxypeptidase N subunit 1 [Source:NCBI gene;Acc:103037340]) HSP 1 Score: 224.557 bits (571), Expect = 1.179e-67 Identity = 148/460 (32.17%), Postives = 225/460 (48.91%), Query Frame = 1
Query: 16 LL*LVMNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDL-GTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLD---QYKRVYNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLD 1368
+L LV + +L++L A+ FQ H EE+V + + +CP IT +Y I +++ LYV F P H A PEF ++ N+HGNE++GRE I + +LC +YL ++ IT LI++ RIH L SMNPDGY + + G+ G N DLN +FPDL G ++ + ++N +H E + + ETL + W+ ++L NLH +V NY + +S + + K Y+ TPDD I++ + + H M K W C Y+ + G+ W S+ G DF+YL TN L LSC + + + W + +L+ Y QVH G+KG+V DE N I NA I ++ + TG GDY+R+L+PG Y + S GY+P V A+ I ++YL P NL+
Sbjct: 1 MLSLVWSGVLLLVLWAPEAQAIDDFQ---HHGYEEMVRALFSVQSQCPYITRIY-----SIGRSVEGRHLYVLEFSDSPGIHEALEPEFKYVGNMHGNEVLGRELLIHLCQFLCEEYLAGNQRITSLIHNTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNSREVDLNRNFPDLNGLMYYYE----KNNGQNHHLPLPDKWELQVEPETLAVIKWMQNYNFILSANLHGGAVVANYPFDKSREARIRGKSTYSATPDDKIFKKLAKAYSYAHSWMHKGW--NCGDYF---EEGITNGANWYSLSKGMQDFNYLYTNCFEITLELSCDKFPPASALSREWLANREALVSYMEQVHHGIKGMVYDENNNPIGNAEISVAGISHD--------ITTGPDGDYFRLLLPGTYTVTASAAGYQPYSSTVTVG-----PAEAIQL-----HFYLKPAPKGTNLN 425
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Match: cpxm1b (probable carboxypeptidase X1 [Source:NCBI gene;Acc:103039765]) HSP 1 Score: 219.164 bits (557), Expect = 6.273e-63 Identity = 126/403 (31.27%), Postives = 210/403 (52.11%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFK--KLEKLEHNMTDH---LFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEW-RVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNR-IVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVD 1275
+ H+ +E+ ++ +H+ CP+IT +Y I K+ +LYV P +H G PEF +++ +HGNE++GRE + + ++C +Y ++ I +L+ RIH L SMNPDGY +++ G+ G +Y D+NH+F DL T + +LE + + +H L + E ET ++W+ +P+VL N H LV Y + + D R PT DD+ +R++ + + + + M R C + N + G+ W +V +DFSYL TN + LSC + + + W + SLL Y QVH G+KGV+RD++ + I +A+IK + I +R+ GDY+R+L PGD+ + VS +GY P+ R +V+
Sbjct: 299 RHHNYKEMRKVLKSVHEACPDITRIY-----SIGKSYTGLKLYVMEISDNPGKHELGEPEFRYVAGIHGNEVLGRELMLNLMQFMCQEYKRGNQRIVRLVKETRIHLLPSMNPDGYEFAYKKGSELSGWALGRYSYEGIDMNHNFADLNTVMWNAIELEMDKSKLINHYLPLPEQYTSEEAFVAPETRAVISWMEAIPFVLSANFHGGELVVTYPFDMTRDWAPRELTPTADDSFFRWLATVYASTNHVMSNPDRRHCHNFDFIRHNNIINGANWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHASELPIEWENNKESLLVYMEQVHRGIKGVIRDKDTDAGIADAIIKVDD--------IDHHIRSAADGDYWRLLNPGDHDVTVSAEGYIPSSRSCRVE 688
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Match: cpxm1a (probable carboxypeptidase X1 [Source:NCBI gene;Acc:103045799]) HSP 1 Score: 216.468 bits (550), Expect = 3.233e-62 Identity = 126/398 (31.66%), Postives = 209/398 (52.51%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFF--KKLEKLEHNMTDHLFTRKKF---LEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVP-NALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNR-IVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIR 1260
+ H+ + ++ +++ KCPNIT +Y I K+ +LYV P +H G PEF +++ +HGNE++GRE + + Y+C++Y ++ I +L+ + RIH L SMNPDGY +++ G+ G ++ D+NH+FPDL + + L + +++H ++ + ET +NW+ +P+VL NLH LV Y + + D R PTPD++ +R++ + + + + M R Y + N + G W +V +DFSYL TN + LSC + + + W ++ SLL Y QVH G+KGV+RD++ I NAV+K V L +R+ GDY+R+L PG+Y ++V +GY P IR
Sbjct: 263 RHHNYNAMRKLLKEVNDKCPNITRIYT-----IGKSYTGLKLYVMEISDNPGKHELGEPEFRYVAGMHGNEVLGRELLLNLMQYICHEYRRGNQRIVRLVKNTRIHLLPSMNPDGYETAYEKGSELAGWALGRYSFENIDMNHNFPDLNNIMWDAQDLATDKKKVSNHYIPMPEYYTTTDATVAPETRAVINWMQDIPFVLSANLHGGELVVTYPFDCTRDWIPRQDTPTPDNDFFRWLAAVYASTNLVMANPDRRICHYEDFQQHNNIINGGDWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHASELPVEWESNKESLLLYMEQVHRGIKGVIRDKDTKEGIANAVVKIVGLDHD--------IRSAVDGDYWRLLNPGEYKVIVWAEGYMPFIR 647
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Match: cpz (carboxypeptidase Z-like [Source:NCBI gene;Acc:103032924]) HSP 1 Score: 211.846 bits (538), Expect = 7.605e-61 Identity = 127/400 (31.75%), Postives = 196/400 (49.00%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTD----------------VY-GFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSL-DQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRV-RCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK 1248
HSN ++++I+ K KCP+I+ Y I +++ L V F K P +H PE I N+HGNE++GR+ I +A YLC++YL +E I LI + RIH L SMNPDGY L +Y G+ G N DLN +FPDL + F+ + + DH+ + K ET M W+ ++P+V+ +LH LV +Y + S + +++++PTPD+ +++ + + H M RC + + G+ W S G DF+YL +N + + L C + + W + +LL + VH G+KG+V+D GN I A+I L R + T E GDY+R+L+PG Y I S GY
Sbjct: 187 HSNAQMINILKKTAAKCPHISRTY-----SIGRSVDGKDLLVIEFSKNPGQHDLLEPEIKLIGNMHGNEVLGRQLLIYLAQYLCSEYLLANERIQTLINNTRIHLLPSMNPDGYELAASEVADSLDPENTNQEGHIYNGWTSGRANAQNIDLNRNFPDLTSIFYNR-RRFRSIRNDHIPIPDSYWISKVAPETYAVMKWIRSIPFVISASLHGGELVISYPFDFSRHPEEEKMFSPTPDEQVFKQLARTYADAHATMSNNDTDRCGASFAN-KGGIINGALWYSFAGGMSDFNYLHSNCLELTVELGCDKFPAEEELYPEWLRNKEALLSFMESVHRGIKGIVKDGNGNGIKGAIISVKGLR--------RDVTTAEDGDYWRLLVPGIYVISASAPGYS 571
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Match: cpe (carboxypeptidase E [Source:ZFIN;Acc:ZDB-GENE-090313-68]) HSP 1 Score: 197.593 bits (501), Expect = 2.120e-57 Identity = 137/415 (33.01%), Postives = 199/415 (47.95%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE----GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQ----SLDQYK--RVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDF 1311
H EEL ++ + +CP+I+ +Y + ++ L V P H G PEF +I N+HGNE +GRE I +A YLCN+Y + ++ I LI+S RIH + SMNPDG+ G + G N DLN +FPDL + + + E +HL KK +++ K ET ++W++ +P+VL NLH +V NY Y + S +Y VYNP D + R KE + G W SV G DF+YLS+N L LSC + ++ +W + SL+ Y QVH GV G VRD +GN I NA + +V D + L T + GDY+R+L PG+Y + S GY I+ V + +A +DF
Sbjct: 45 HRYEELRKALVAVWLQCPSISRIYT-----VGESSEGRELLVLEISDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIYLAQYLCNEYQQGNDTIINLIHSTRIHIMPSMNPDGFEKAASQSGEMKDWFVGRTNAQGIDLNRNFPDLDRIVY--MNEREGGANNHLLKNMKKAVDENTKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRSGSTHEYSAYSVYNPVMSDP--KRAPCRKNDDDSSFKE--------------GITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPPENTLKMYWDQNRNSLINYLEQVHRGVAGFVRDLQGNPISNASV-SVEGIDHD-------LTTAKDGDYWRLLTPGNYKVSASAPGYLTVIKKVAVSST---TATRLDF 425
BLAST of carboxypeptidase E vs. Ensembl Sea Lamprey
Match: cpz (carboxypeptidase Z [Source:ZFIN;Acc:ZDB-GENE-090313-267]) HSP 1 Score: 206.453 bits (524), Expect = 1.073e-59 Identity = 125/418 (29.90%), Postives = 202/418 (48.33%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTD-VYGF------GEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKE-WRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIK-TVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSE 1326
+ + E+ + + K C +Y I K+ + L V + P +H +PE + N+HGNE++GRE + +A +LC + + DE + +L+ + R+H L SMNPDGY L D V G G NN DLN +FPDL + ++ ++ T L ++ + K ET ++W+ P+VL NLH L+ Y Y SL ++ Y+ TP+D ++R + + HP M + + CP + G+ W S + G DFSYL + + L L C + ++ W + +LL + VH G+KGVVRDE G I A I NL D+ T G+++R+L PG Y + S+ GY+ ++ ++ + S +V DF+LP +
Sbjct: 179 RHRRHAEMTRALRRAEKSCGGAARLY-----SIGKSFENRDLLVIELSENPGKHELLVPEVRLVGNIHGNEVLGRELLVALAQHLCARLEDGDERVRRLLNTTRLHILPSMNPDGYELAADSVSGSVANAADSSGRNNMQNIDLNRNFPDLTSGVLRRPKR----RTQPLPVPDQYWDGKVAPETRAVIDWMEEFPFVLAGNLHGGELLVRYPYDASL-MGEKFYSATPEDQMFRLLARTYAEAHPLMSDKHKAPCPGETGAPSGGIVNGAEWYSFRGGMPDFSYLHSGCLELTLELGCVKFPSGEDLPIEWAHNREALLTFVEAVHQGIKGVVRDERGAGIGGARISIKGNLRDTV---------TAPSGEFWRLLPPGSYIVRASRAGYRAVVKRVRLPARLQTSGRV-DFKLPRQ 576
BLAST of carboxypeptidase E vs. Ensembl Sea Lamprey
Match: CPXM2 (carboxypeptidase X, M14 family member 2 [Source:HGNC Symbol;Acc:HGNC:26977]) HSP 1 Score: 199.134 bits (505), Expect = 3.361e-57 Identity = 119/403 (29.53%), Postives = 201/403 (49.88%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDG----YLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEK--LEHNMTDHLFTRKKFLEKKYQR---ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNP--TPDDNIYRYIGSRFVARHPEMKEWRVR-CPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
+ H+ +E+ +M +++KCPN+T +Y +I K+ +LY P H G PEF +++ +HGNE +GRE ++ + ++LC++Y + I +L+ RIH L S+NPDG Y +++ G+ G DLNH+FPDL + + + + H + +H + + ET ++W+ +P+VL NLH LV Y + + + + R + P TPD+ I+R++ + + H M + R C + G+ W +V DFSYL TN + LSC + + W + +LL + QVH G+KG+V D +G I NA+I + + T GDY+R+L PG+Y + K+G+ PA + +V
Sbjct: 182 RHHNYKEMRLLMKIVNEKCPNVTRIY-----NIGKSHEGLKLYAMEISDNPGEHEIGEPEFRYVAGVHGNEALGRELTLFLMEFLCHEYNRGNPRIRRLVEETRIHLLPSVNPDGYEKAYEAGSELSGWTFGRWTRNGIDLNHNFPDLNSVLWDAENRGHVSHGVPNHHLPLPDWFHSRNATVAVETRAVVSWMEKIPFVLGGNLHGGELVVTYPFDAAREPW-RAHEPSATPDEQIFRWLAFLYASTHRTMTDANRRVCHGQDFTKDEGVINGAEWHAVTGSMGDFSYLHTNCFEVTMELSCDKFPHETELPQEWENNREALLVFLEQVHRGIKGIVTDADGEGIPNAIISVDEINHD--------VTTASGGDYWRLLNPGEYRVTARKEGFVPAAQNCQV 570
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Match: EDO46958 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNN3]) HSP 1 Score: 202.216 bits (513), Expect = 2.089e-60 Identity = 129/411 (31.39%), Postives = 203/411 (49.39%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEM----KEWRVRCPTYWL-YVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
+ H+ EE+ ++ K +K NIT +Y D+ ++ + +L+V P +H PE + +N+HGNE++G+E + + YLC+ Y ++ IT L+ S RIH L S+NPDGY + G N DLN +FPD +FF Q ET M+W+ + P+VL +LHS +LV NY Y + + +Y+ TPDD+++R + + HP M W+ CP + + + G+ W S+ G D++Y+ +N L L C++ + + +W + +LL Y Q H GV GVVRDEEG+ I NA I N + T + GDY+RIL+PG Y + VS +G++ KV ++ A +DF L
Sbjct: 5 RHHNYEEMTWLLKKYSRKYTNITRLY-----DVGTSVQNRKLWVMEISDNPGKHEVKEPEMKYTANIHGNEVVGKEMLLHLIRYLCHNY-GVNKRITDLVDSTRIHILPSLNPDGYEMAAQKTKTHTGTKNANGVDLNRNFPD---QFFPSTTGPP------------------QPETRAIMDWIKSNPFVLSASLHSGSLVANYPYDDNPSG-QSLYSATPDDDVFRQLARAYSEAHPTMHLANSPWK--CPDKQREHFIDGITNGARWYSISGGMQDYNYVHSNAFEITLELGCEKFPNASALPEYWDENKEALLGYIEQTHRGVYGVVRDEEGDPIENARISITNRRHD--------VFTAKDGDYWRILVPGSYEVTVSARGFEHET---KVASVSPSKATSLDFTL 374
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Match: EDO41722 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3G8]) HSP 1 Score: 199.519 bits (506), Expect = 2.357e-59 Identity = 127/418 (30.38%), Postives = 203/418 (48.56%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR---TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEM----KEWRVRCPTYWLYVP-----NALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
K H+ +E + + ++H + PNIT +Y I K++ L+V P +H G PEF +I+N+HGNE++G+E + A YLC+ Y ++D+ +TK + + R+H L SMNPDGY L + + G +N DLN +FPD +FFK + Q ET M W+ VP+VL NLH +LV NY + S K Y+ +PDD++++ + + HP M W CP VP + + G+ W SV G D++Y+ +N + C++ + +W+ + SLL + VH+GVKG V+D +G I A I + + T GD++R+L PGDY + G++ + V +K A ++F+L
Sbjct: 2 KHHNYDETLSFLKELHGQFPNITRLY-----SIGKSVEGRDLWVIALSSTPNKHEPGKPEFKYIANMHGNEVVGKEVLLTFAKYLCDNY-KKDDEVTKALDTTRVHLLPSMNPDGYELAFKGDNRKNWIIGRSNSKNVDLNRNFPD---QFFKS------------------STGEPQPETKAVMKWIKEVPFVLSANLHGGSLVANYPFDDSPSG-KSEYSKSPDDDVFQSLAKAYSENHPTMHLDNPPW--ECPE----VPPDHFNDGITNGAKWYSVSGGMQDYNYVHSNCFEITVEQGCKKFPAAEELPRYWKENKKSLLSFLDMVHIGVKGFVKDTQGVPIPGARISVEGHK--------KDIFTASDGDFWRLLNPGDYKVTAFADGFEDQTKTVTV---NKGPATEVEFDL 374
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Match: EDO46885 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNN4]) HSP 1 Score: 188.348 bits (477), Expect = 2.791e-55 Identity = 120/394 (30.46%), Postives = 192/394 (48.73%), Query Frame = 1
Query: 103 QHSNEELVDIMIKIHK-KCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE---GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEM----KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIR 1260
QH N E + +K K P+IT +Y + Y ++ + +L+ P +H G PEF +I+N+HGNE++GRE + + YLC Y E E + L+ + RIH L S+NPDGY L + V G G N + DLN +FPD +FF Q ET MNW+ P+VL +LHS LV Y Y S + +Y+ TPDD+++R++ + HP M +W ++ + + G++W S+ G D++Y+ +N + + C+R ++ +W+ + LL QVH GV G V++ +G + NA IK + + + + GDY+R+L+PG Y + S GY+P +
Sbjct: 3 QHHNYEKLTWFLKYFSLKYPDITRLYSIGY-----SVQNRKLWAMEISDNPGQHEPGEPEFKYIANIHGNEVVGRELLLQLIRYLCENY-ESHEKVRTLVDTTRIHILPSINPDGYELAS-VKGKTHKFIGRRNAYGVDLNRNFPD---QFFPSSNGPP------------------QPETRAVMNWIRDYPFVLSASLHSGALVALYPYDDSPSG-QSLYSATPDDDVFRHVAKTYSELHPVMHLANPKWNCSNVKEEHFI-DGITNGASWFSISGGMQDYNYVHSNDFEVTVEVGCERFPKEDQLEKYWKDNKKPLLELINQVHRGVHGFVKNIQGEPLANAFIKVSDRRHD--------VTSAKDGDYWRLLVPGSYEVTASATGYEPQTK 358
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Match: EDO31956 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWF6]) HSP 1 Score: 182.956 bits (463), Expect = 5.408e-53 Identity = 120/386 (31.09%), Postives = 190/386 (49.22%), Query Frame = 1
Query: 103 QHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGY--LLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYN-PTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGD--YAIMVSKQGY 1245
H+ E + ++ K +K+ P+IT +Y + KT+ + L V P +H G PEF +I N+HGNE++ RE + + YL Y E E + KL+ S RIH + SMNPDGY + D G G N DLN +FPD +F E+ E+N Q ET + M+W+ + P+VL NLH +LV NY + KR + P+PDD +++ + + H M + CP + G+ W SV G D++YL +N L +SC + + + W + P+LL Y +VH G+KGVV+D G I +A I + + + + ++ GD++R+++P + Y++ V GY
Sbjct: 7 HHNYEAMKGLLEKFNKEYPDITRLY-----SVGKTVENRDLLVLEISDKPGKHEKGEPEFKYIGNMHGNEVVSREILLQLIGYLLKNYQENSE-LKKLVDSTRIHIMPSMNPDGYEKAVMGDCQGV-TGRANANGIDLNRNFPD---QF---AERKENN--------------PLQPETKLVMSWIKSNPFVLSANLHGGSLVANYPFDDYDPNGKRSGDSPSPDDPLFKSLARTYADAHKTMHLNKPPCPGDPDQFDGGITNGAHWYSVSGGMQDYNYLHSNAFEITLEVSCCKFPAASTLSDFWDKNKPALLSYINRVHTGMKGVVQDNMGKPIKDARI----ILEGNSHAV----KSAADGDFWRLVLPRNKPYSVRVEAPGY 357
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Match: EDO41344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4K6]) HSP 1 Score: 192.2 bits (487), Expect = 5.990e-53 Identity = 117/387 (30.23%), Postives = 188/387 (48.58%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFG-EGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQR-ETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTY--WLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYK 1248
K H+++E+ + K+H+ P+IT +Y Y ++ L+V P H G PEF ++ N+HGNE++GRE +L+ LC Y R IT L+ RIH + SMNPDG+ + + G N DLN +FPD ++ E +Q ET + WL P+VL NLH ++V NY + + +R Y+ +PDD +++Y+ + HP M + CP N + G+ W +VK G D++YL +N + +SC + +Q W + SL+ + QVH+GV+G V+ + G I NAVI I + +G+ GDY+R+L+ G+Y + + +GY+
Sbjct: 426 KHHTHKEMTSFLKKVHELYPHITRLYSAGY-----SVKGRELWVMEISDNPGTHEPGEPEFKYVGNMHGNEVVGREMLLLLIQVLCENY-HRISSITALVDYTRIHIMPSMNPDGHAVSIEGDKQSVTGRPNAHHVDLNRNFPDQFSD-----------------------EDGHQEPETKAIIKWLSEYPFVLSANLHGGSVVANYPFDDTEYGEER-YSKSPDDIVFKYLALSYSLAHPTMSNNKPACPETDPGEVFKNGITNGAAWYNVKGGMQDYNYLHSNCFEITVEMSCNKYPYRTQLQHFWNDNKVSLITFMAQVHIGVRGFVKSDSGESIPNAVISVEG--------INHHVLSGKDGDYWRLLLKGNYKLTAAAKGYQ 774 HSP 2 Score: 165.622 bits (418), Expect = 7.800e-44 Identity = 119/409 (29.10%), Postives = 199/409 (48.66%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERD-EYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFG-EGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV---YNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
H+ +EL ++ K+ I ++ + K++++ L+ +P G P F ++ N+HGNE +GR+ I + YL Y + E ITKL+ S I+ + SMNPDG+ ++ G G N +LN +FPD + L++++++ Q ET + W+ P+VL NLH +LV +Y + ++Y R Y+ +PDD I+R + + H MK RC T++ N + G+ W V G D +YL +N L LSC + + W+ + +LL Y +VH G+KG VRD GN I AV+ + I + + T GD++R+L+PG+Y ++V+ G+ A R + ++K SA ++F L
Sbjct: 2 HNYDELTRLLESYSKRYKKIARLH-----SVGKSVLNRHLWALQITDHPDIIEPGEPMFKYVGNMHGNEAVGRQILIYLVQYLLENYGKTGHERITKLVNSTNIYIMPSMNPDGFERSKELDCDGLVGRRNENNVNLNRNFPDQFNNW------LDYDVSN------------AQPETKAVIKWIYENPFVLSANLHGGSLVASYPFDS--NRYHRPFWYYSKSPDDEIFRELALTYSRHHHTMKNGDPRCHTHF---KNGITNGAYWYDVPGGMQDINYLISNCFEITLELSCCKYPNSTELPKEWKNNKNALLTYMEEVHKGIKGFVRDRSGNGIQGAVVHVLG--------IKKNVTTARHGDFWRLLVPGNYTVLVTAPGFHQAKRTDII--VEKSSAIEVNFVL 372 HSP 3 Score: 85.1149 bits (209), Expect = 1.862e-17 Identity = 40/120 (33.33%), Postives = 68/120 (56.67%), Query Frame = 1
Query: 103 QHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTD 462
H +E+ M + K+CP I +Y I ++ R++V P H G PEF +++ +HGNE++G+E +L+ +LC Y +D+ +T+L+ S R+HFL MNPDG ++ +
Sbjct: 1182 HHQPDEIGKWMQTMAKRCPKIAHVY-----SIGMSVQFRRIWVMELSDKPGVHQPGKPEFSYVAGIHGNEVVGKEMVLLLIQHLCLSY-GKDDMVTRLVDSTRLHFLPLMNPDGGVVAQE 1295 HSP 4 Score: 82.0333 bits (201), Expect = 2.200e-16 Identity = 77/387 (19.90%), Postives = 161/387 (41.60%), Query Frame = 1
Query: 106 HSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDG--YLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIR 1260
H + + ++ + KCP I ++ I K+ +++ P + P G + +L G+++IGRE + + YLC Y ++ + KL+ + R+H + +++ DG D G + NN + +D P+ T ++ +K+ D + K+ L ++ + L + ++ AT T D+ + I + + HP+MK C N + KG+TW + D++YL N++ + F+SC + + + +++ ++ + ++ H + G+++ I NA ++ N S+ + + + +Y+IL PG Y + S GY A +
Sbjct: 817 HDYKTMTQMLQSYYLKCPGI-----IRLQSIGKSQEGRKIWSLEISVNPGQENPYKPNVGMVGSLQGSDVIGREMLLALVGYLCEGYKSKEARVVKLLQTTRLHVVPAVDVDGNEKAREGDCQGKLDS-NNDISKSFYYDMPE-NTRMRRESDKI-----DSVSRVKRGLNF-----NVIFQLYPLNAQYTGNPHVKGAT--------------------TSDEKTFIDIATTYARSHPKMKLGH-GCNGSIPQFANGITKGATWREMHYTMQDYAYLDMNILQLSFFVSCCKYPPIDSFESILKSNAIPMINFIKKSHQALTGIIQTFNHTPIHNASLRVHN---SKIKIDIGLKNS----SFYKILAPGKYILKASAPGYSTATK 1158
BLAST of carboxypeptidase E vs. Ensembl Medaka
Match: cpn1 (carboxypeptidase N subunit 1 [Source:NCBI gene;Acc:101156125]) HSP 1 Score: 215.698 bits (548), Expect = 1.221e-64 Identity = 134/411 (32.60%), Postives = 204/411 (49.64%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV-----YNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKV 1302
K H EE+V + + +CP IT +Y I +++ LYV F P H A PEF ++ N+HGNE++GRE I +A +LC +Y R++ IT+LI+ RIH L SMNPDGY + + G+ G N DLN +FPDL + EK +N +H E++ + ETL + W+ + +VL NLH +V NY + +S +Y R+ + TPDD ++R + + H M K W C ++ + G++W S+ G DF+YL TN L LSC + + + W + +L+ Y QVH G+KG+V DE N I A I + + +G GDY+R+L+PG Y + S GY P+ V + ++
Sbjct: 28 KHHRYEEMVRALFAVQNECPYITRIY-----SIGQSVEGRHLYVLEFSDNPGIHEALEPEFKYVGNMHGNEVLGRELLIKLAQFLCEEYQARNQRITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNAREIDLNRNFPDLNALMY-YYEK--NNGRNHHLPLPDNWEQQVEPETLAVIKWMQSYNFVLSANLHGGAVVANYPFDKS--RYPRIRGRTTHADTPDDKLFRKLARTYSYAHSWMHKGW--NCGDFF---DEGITNGASWYSLSKGMQDFNYLYTNCFEITLELSCNKFPPESTLPGEWMANREALVSYIEQVHHGIKGMVYDENNNPIRKAEISVAGINHD--------VTSGVDGDYFRLLLPGTYTVTASAPGYLPSTSTVTVGPAEAIQVRL 415
BLAST of carboxypeptidase E vs. Ensembl Medaka
Match: cpn1 (carboxypeptidase N subunit 1 [Source:NCBI gene;Acc:101156125]) HSP 1 Score: 214.927 bits (546), Expect = 5.947e-64 Identity = 134/401 (33.42%), Postives = 201/401 (50.12%), Query Frame = 1
Query: 100 KQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRT----DVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRV-----YNPTPDDNIYRYIGSRFVARHPEM-KEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKV 1272
K H EE+V + + +CP IT +Y I +++ LYV F P H A PEF ++ N+HGNE++GRE I +A +LC +Y R++ IT+LI+ RIH L SMNPDGY + + G+ G N DLN +FPDL + EK +N +H E++ + ETL + W+ + +VL NLH +V NY + +S +Y R+ + TPDD ++R + + H M K W C ++ + G++W S+ G DF+YL TN L LSC + + + W + +L+ Y QVH G+KG+V DE N I A I + + +G GDY+R+L+PG Y + S GY P+ V
Sbjct: 28 KHHRYEEMVRALFAVQNECPYITRIY-----SIGQSVEGRHLYVLEFSDNPGIHEALEPEFKYVGNMHGNEVLGRELLIKLAQFLCEEYQARNQRITRLIHDTRIHILPSMNPDGYEVAARQGPEFNGYLVGRGNAREIDLNRNFPDLNALMY-YYEK--NNGRNHHLPLPDNWEQQVEPETLAVIKWMQSYNFVLSANLHGGAVVANYPFDKS--RYPRIRGRTTHADTPDDKLFRKLARTYSYAHSWMHKGW--NCGDFF---DEGITNGASWYSLSKGMQDFNYLYTNCFEITLELSCNKFPPESTLPGEWMANREALVSYIEQVHHGIKGMVYDENNNPIRKAEISVAGINHD--------VTSGVDGDYFRLLLPGTYTVTASAPGYLPSTSTVTV 405
BLAST of carboxypeptidase E vs. Ensembl Medaka
Match: cpe (carboxypeptidase E [Source:NCBI gene;Acc:101160712]) HSP 1 Score: 211.075 bits (536), Expect = 1.587e-62 Identity = 140/444 (31.53%), Postives = 216/444 (48.65%), Query Frame = 1
Query: 25 LVMNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG----FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW----LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPS 1323
L+ ++ L ++ F+ H +EL ++ + +CP +T +Y ++ L V P H G PEF +I+N+HGNE +GRE I +A YLCN+Y + +E I LI++ RIH + SMNPDG+ G + G +N DLN +FPDL + + + E HL KK +++ K ET ++W++ +P+VL NLH +V NY Y ++ Y+ +PDD ++ + + +P M + + R P + + G W SV G DF+YLS+N L LSC + ++ +W + SL+ Y QVH GVKG VRD +GN I NA I +V D + + + + GDY+RIL PG+Y + + GY I+ V A +DFEL S
Sbjct: 6 LLFGAAVVALTRAAASDGEISFEY---HRYDELRKALVSVWLQCPTVTRIYT-----TGESFEGRELLVLEMTDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHNTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGIDLNRNFPDLDRIVY--INEREGGANHHLLQNMKKAVDENPKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVTFKSLAKAYSMYNPVMSDPQ-RPPCRKNDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPSEDTLKTYWEQNRNSLVNYIEQVHRGVKGFVRDLQGNPISNATI-SVEGIDHD-------ITSAKDGDYWRILAPGNYKVAATAPGYLTVIKKVAV---PYSPAARVDFELES 427
BLAST of carboxypeptidase E vs. Ensembl Medaka
Match: cpe (carboxypeptidase E [Source:NCBI gene;Acc:101160712]) HSP 1 Score: 211.075 bits (536), Expect = 1.587e-62 Identity = 140/444 (31.53%), Postives = 216/444 (48.65%), Query Frame = 1
Query: 25 LVMNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG----FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTR-KKFLEK--KYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYW----LYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPS 1323
L+ ++ L ++ F+ H +EL ++ + +CP +T +Y ++ L V P H G PEF +I+N+HGNE +GRE I +A YLCN+Y + +E I LI++ RIH + SMNPDG+ G + G +N DLN +FPDL + + + E HL KK +++ K ET ++W++ +P+VL NLH +V NY Y ++ Y+ +PDD ++ + + +P M + + R P + + G W SV G DF+YLS+N L LSC + ++ +W + SL+ Y QVH GVKG VRD +GN I NA I +V D + + + + GDY+RIL PG+Y + + GY I+ V A +DFEL S
Sbjct: 6 LLFGAAVVALTRAAASDGEISFEY---HRYDELRKALVSVWLQCPTVTRIYT-----TGESFEGRELLVLEMTDNPGTHEPGEPEFKYIANMHGNEAVGRELLIYLAQYLCNQYQQGNETIIDLIHNTRIHLMPSMNPDGFEKAASQPGEIKDWFVGRSNAQGIDLNRNFPDLDRIVY--INEREGGANHHLLQNMKKAVDENPKLAPETKAVIHWIMDIPFVLSANLHGGDVVANYPYDETRTGSTHEYSASPDDVTFKSLAKAYSMYNPVMSDPQ-RPPCRKNDDDSSFKDGITNGGAWYSVPGGMQDFNYLSSNCFEITLELSCDKFPSEDTLKTYWEQNRNSLVNYIEQVHRGVKGFVRDLQGNPISNATI-SVEGIDHD-------ITSAKDGDYWRILAPGNYKVAATAPGYLTVIKKVAV---PYSPAARVDFELES 427
BLAST of carboxypeptidase E vs. Ensembl Medaka
Match: cpxm1b (probable carboxypeptidase X1 [Source:NCBI gene;Acc:101168129]) HSP 1 Score: 216.853 bits (551), Expect = 2.506e-62 Identity = 128/402 (31.84%), Postives = 210/402 (52.24%), Query Frame = 1
Query: 91 QLNKQHSN-EELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLR----TDVYGFGEGHNNYFFQDLNHDFPDLGTEFFK--KLEKLEHNMTDHLFTRKKFLEKK---YQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVR-CPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRD-EEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIR 1260
QL+ +H N +E+ +M ++++CP+IT +Y I K+ +LYV P +H G PEF +++ +H NE++GRE + + YLC ++ D+ + +L+ RIH L SMNPDGY +++ G+ G +Y D+NH+F DL + + +LE + +H F + + ET ++W+ +P+VL NLH +V Y + + D R + PTPDD+ +R++ + + + + M + R C N + G+ W +V +DFSYL TN + LSC + + + WR + SLL + QVH G+KGV+RD E G I AVIK I +R+ GD++R+L PG+Y + V+ +GY P+ R
Sbjct: 256 QLDFRHHNYKEMRKLMKSVNEECPDITRIY-----SIGKSHGGLKLYVMEISDNPGKHELGEPEFRYVAGMHRNEVLGRELLLNLMQYLCREFKRGDQRVVRLVQETRIHLLPSMNPDGYETAFKKGSELAGWALGRYSYEGIDMNHNFADLNSVMWTAMELETDRSKLINHYFPIPEQYTSEDAFVASETRAVISWMQDIPFVLGANLHGGEVVVTYPFDMTRDWAPREHTPTPDDSFFRWLAAAYASTNQVMSDPDRRPCHNKDFLRNNNIINGAAWHNVPGSMNDFSYLHTNCFEITVELSCDKFPHASELPLEWRNNRESLLVFMEQVHRGIKGVIRDRESGEGIAGAVIKVEE--------IDHHIRSVADGDFWRLLNPGEYQLTVTAEGYMPSSR 644
BLAST of carboxypeptidase E vs. Planmine SMEST
Match: SMESG000062760.1 (SMESG000062760.1) HSP 1 Score: 956.436 bits (2471), Expect = 0.000e+0 Identity = 457/458 (99.78%), Postives = 458/458 (100.00%), Query Frame = 1
Query: 31 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV 1404
MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHN+TDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV
Sbjct: 1 MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNVTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV 458
BLAST of carboxypeptidase E vs. Planmine SMEST
Match: SMESG000062760.1 (SMESG000062760.1) HSP 1 Score: 886.33 bits (2289), Expect = 0.000e+0 Identity = 423/424 (99.76%), Postives = 424/424 (100.00%), Query Frame = 1
Query: 133 MIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV 1404
MIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHN+TDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV
Sbjct: 1 MIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNVTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNRIVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFELPSEYYYLDPECIRFNLDQTTVHELLEMKV 424
BLAST of carboxypeptidase E vs. Planmine SMEST
Match: SMESG000037720.1 (SMESG000037720.1) HSP 1 Score: 303.138 bits (775), Expect = 1.082e-97 Identity = 159/432 (36.81%), Postives = 251/432 (58.10%), Query Frame = 1
Query: 43 ILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYG-FGEGHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNYGYQQSLDQYKRVYNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVV--RDEEGNR-IVNAVIKTVNLTDS---EPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
I V L+L ++ + + H+N EL +I+ +I+ KC +IT +YYL+ GD+DKT+ +NRLYV FGK P RH GIPEF ++ N+HGNE++GRE + +ADYLC++++ +E++ ++ S RIH L SMNPDG+ + + G N DLN +FPDL FK E DHL +K E + +RETLM + W+ ++P+VL N+H +V NY Y +S K + TPD+ +++++ + +P M + + CP + + G+ W S+ G DF+YL+TN L + C++ + W + SL+ + + H+G+KG+V R E G + + AVIK N+T + EP I+ + T GDYYR+L+PG Y+++ + G+K I+C V N +FSAKV++F L
Sbjct: 8 IFVFLVLEASGKIEY----RHHNNIELKNILERINDKCSSITHLYYLRSGDVDKTVHNNRLYVIAFGKSPDRHIPGIPEFKYVGNMHGNEVVGRELLLFLADYLCDQHVAGNEWVRNIVESTRIHILPSMNPDGWQIANRTRNEWVVGRTNANNVDLNRNFPDLDKVVFKNSEL--GGKQDHLLNKKTIDEDELERETLMVIAWITSIPFVLSANIHGGDVVANYPYDKSTVDGKNQASLTPDNEVFKFLALSYSKYNPRMFKRKDSCPNSDFLPKDGITNGAKWYSLSGGMQDFNYLATNCFEITLEVGCRKFPDGKFLYDFWMLNYKSLMNFIQATHIGIKGIVLGRSESGYKPVAKAVIKVTNVTAAGQVEP--ILHHVTTASEGDYYRLLVPGRYSVIAAAPGFKSQIQCVLVTNESQFSAKVLNFRL 431
BLAST of carboxypeptidase E vs. Planmine SMEST
Match: SMESG000073389.1 (SMESG000073389.1) HSP 1 Score: 192.971 bits (489), Expect = 1.084e-53 Identity = 133/415 (32.05%), Postives = 201/415 (48.43%), Query Frame = 1
Query: 91 QLNKQHSNEELVDIMIKIHKKCPNITTMYYLKYGDIDKTIMHNRLYVTVFGKYPTRHTAGIPEFGWISNLHGNEIIGREFSILMADYLCNKYLERDEYITKLIYSMRIHFLSSMNPDGYLLRTDVYGFGE-GHNNYFFQDLNHDFPDLGTEFFKKLEKLEHNMTDHLFTRKKFLEKKYQRETLMTMNWLLTVPWVLQVNLHSATLVFNY---GYQQSLDQYKRV-YNPTPDDNIYRYIGSRFVARHPEMKEWRVRCPTYWLYVPNALQKGSTWLSVKNGWHDFSYLSTNLMGNNLFLSCQRNMLPANIQFHWRTSLPSLLYYFRQVHMGVKGVVRDEEGNR-IVNAVIKTVNLTDSEPYVIMRFLRTGELGDYYRILIPGDYAIMVSKQGYKPAIRCFKVDNLDKFSAKVIDFEL 1317
L K H+ EL + + IH P IT +Y I ++ N L+V K P H G+PEF +I N+HGNE++GRE I + + C Y + D +T I + RIH + +MNPDG+ + GE G +N +DLN +FPD FKK +K + + ET MNW+ +VL N H +LV NY YQ + ++ Y+ +PDD ++ + + H MK CP PN + G+ W SV G D++Y+++N + +SC++ L + + +W + SL+ + QVHMG+KG V D R I NA T+N+ I + T GDY+R+L PG Y++ V K Y+P +V + SA +F L
Sbjct: 14 NLTKYHTQVELTNFLKNIHSLYPTITRLY-----SIGNSVSGNPLWVMEISKKPGFHIPGVPEFKYIGNMHGNEVVGRELLIGLIELFCVNYGKND-LLTSFINNTRIHIMPTMNPDGFKKSREGDFNGEFGRSNMNNKDLNRNFPDQ----FKKNDK------------------QLEPETKAVMNWIRQYSFVLSANFHGGSLVANYPFDNYQSTNANAMQIRYSASPDDKLFIQLAKSYSMAHQNMK-IGGPCPGETEQFPNGITNGAKWYSVNGGMQDWNYMNSNCFEITVEVSCKKYPLKSELNRYWNQNKYSLINFMAQVHMGLKGFVHDTISQRPISNA---TINVKG-----INHHIFTAIDGDYWRLLTPGKYSVEVKKDRYRPVRHSIEV--FENVSATQNNFNL 389 The following BLAST results are available for this feature:
BLAST of carboxypeptidase E vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of carboxypeptidase E vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of carboxypeptidase E vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of carboxypeptidase E vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of carboxypeptidase E vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of carboxypeptidase E vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of carboxypeptidase E vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002098 ID=SMED30002098|Name=carboxypeptidase E|organism=Schmidtea mediterranea sexual|type=transcript|length=1475bpback to top protein sequence of SMED30002098-orf-1 >SMED30002098-orf-1 ID=SMED30002098-orf-1|Name=SMED30002098-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=459bp MNFCILVLLILVSTVAVYCFQLNKQHSNEELVDIMIKIHKKCPNITTMYYback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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