Doublecortin domain-containing protein 2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30002064 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 19
Homology
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Match: DCDC2 (doublecortin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18141]) HSP 1 Score: 124.02 bits (310), Expect = 3.284e-29 Identity = 90/358 (25.14%), Postives = 180/358 (50.28%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDK-IESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPK---------NSEKRSLKKQ----KNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQD 1158
+VK++L+++NGD ++ G+RVV+++K ++E FL+++T + GA+R++ TP G RI+ L+ + + G YVA + E+ K +NY +++ + + +P+ + N ++ I SRI + + + I++ NGD PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N+ + + S +++ +P NSEK + KQ KN E + F+ R E A E E + V +P + +P E+D
Sbjct: 15 VVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQ-EAFKKLNY---LDIGEI---------KKRPMEVVNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKA----SSLPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQE--DEDTQVEVPVDQRPAEIVDEEED 352
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Match: DCDC2B (doublecortin domain containing 2B [Source:HGNC Symbol;Acc:HGNC:32576]) HSP 1 Score: 99.7525 bits (247), Expect = 6.768e-22 Identity = 72/276 (26.09%), Postives = 128/276 (46.38%), Query Frame = 1
Query: 136 SVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK---SNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKP 954
S K +++++NGD +FPG ++VV ++ P E FL ++T ++ A+R + TP HG + +L DL G+YVA +++ ++ LPH K S RL+ + D R Q + I+VF+NGD +P + + + ++K + ++V LQ + ++ TL G + K++ G +YVA + F+++ Y ++L VPS + + Q P KS QG+ E ++KP
Sbjct: 5 SPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQ-APLAVRALYTPCHGHPVTNLADLKNRGQYVA---------AGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGA-VCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELL-------VPSP-SLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKP 259
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Match: DCDC2C (doublecortin domain containing 2C [Source:HGNC Symbol;Acc:HGNC:32696]) HSP 1 Score: 90.8929 bits (224), Expect = 6.633e-19 Identity = 65/240 (27.08%), Postives = 125/240 (52.08%), Query Frame = 1
Query: 112 KNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLR-LANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSK 828
+ P ++ K I++++NGD ++ GK+ V++++ +E LE +T+ ++ G +R + TP G R+ L+ L GKYVA + E K ++Y ++ +P + +LK ++ + + DI+ + S+ Q + S I VF NG F P K++I +++ I ++V +R+++T+NG ++ +KD+++ FYVA E F + P + RVPS+
Sbjct: 4 RGPSAPVDTTPAKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFG-VRRLFTPTRGHRVLGLDALQAGGKYVAAGR-ERFKELDY-----IHIVPRKP-AKIRKLKEIKPVVHCDIN-VPSK-WQTYHRISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKVFPLGG--VRKLFTMNGHLLGDSKDLQDNHFYVAVGLETF------KYFPYWKSPRVPSE 225
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Match: ASPM (abnormal spindle microtubule assembly [Source:HGNC Symbol;Acc:HGNC:19048]) HSP 1 Score: 61.2326 bits (147), Expect = 1.017e-8 Identity = 89/353 (25.21%), Postives = 140/353 (39.66%), Query Frame = 1
Query: 1315 NKAATKIQAGFRGYQTRQRL-KFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTR---HTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXR----------------IQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI-----SEKPVTKPKS----LSPEEQAQERNDAAAKIQAAFRGH 2286
NKAA IQ+ +R Y+T+++ + I + + K +T+ + +Y K A KIQ+ +RG R+ + + M +AA I+A F+ +Q+R HT++ R GK Q K I KAV +QA FRG R+R +L+ AA IQ+ +R Y+ + + + + +R IQA FRG K R + K AA IQ FR R+ F+ K+A IQ +R++ K + V K +S ++ +E + AA IQ+ FR H
Sbjct: 2044 NKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIK------ITNHQHKEYLNLKKTAIKIQSVYRGIRVRR---------------------------------HIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQ----REKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKAR-----RHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMH 2348 HSP 2 Score: 58.9214 bits (141), Expect = 5.117e-8 Identity = 39/129 (30.23%), Postives = 68/129 (52.71%), Query Frame = 1
Query: 1795 EIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKE 2181
+++KA +QA +RGY++R +K + AA +IQ+ FRGY R + ++ +IQ +R +KT + A I +Q+ +RG+K RK+ + ++A KIQ+ FR K +K+
Sbjct: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKR-----------VKYQSVLQSIIKIQRWYRAYKT-LHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQ 1916 HSP 3 Score: 56.9954 bits (136), Expect = 1.805e-7 Identity = 92/372 (24.73%), Postives = 156/372 (41.94%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTRQRLK---------------FNKPEIKQSKISQNPKKSQPESLTSEKESD---YNIKDKAAA-KIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGY-----------QTRH---TLQNKVPRKTNNEREKQNGKN--------QEPTNENKDKEIEKAVITIQAGFRGYRI---RNSLKVRDKAAQ-RIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKT----RKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGH 2286
KAAT +QA +RGY+ RQ +K +NK +K + Q+ K Q + D + +K KAA +Q+ +RG+ R+ ++ + + K Q+ R+ +T AA++IQ +FR + + RH LQ+ KT + ++ K + + K K ++KA + IQ +R Y I +N L ++ KAA +Q+ +RG + R+ +K N+ IQ+ +R +KT+K+ IQ +RG K KE++ K+A KIQ+ +R + R+ I Q + AA I+A F+ H
Sbjct: 1803 KAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNK-RVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMAKAQKQFRLFKT----------AALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVT-----------IQSKYRAYKTKKKYATYRASAII-----IQRWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHI-----------------QHMHRAATFIKAMFKMH 2130 HSP 4 Score: 53.1434 bits (126), Expect = 3.041e-6 Identity = 88/351 (25.07%), Postives = 143/351 (40.74%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTRQRLK-------FNKPEIK--QSKISQNPKKSQPESLTSEKESDYNIKD---------KAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS*II 2316
K A KIQ+ +RG + R+ ++ F K K QS+IS + + + + Y K KA +QA FRG R+ L+ M+ AA +IQ+++R Y+ + T NK+ + T +++ + + ++ +VI IQA FRG + R LK+ AA IQ FR RR + ++ A IQ +R + + +NA IKIQ+ +R + RK ++A IQ+ FR ++ K S+ ++Q Q + AAK+Q R H R+ HS +I
Sbjct: 2095 KTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRK---------------------------------MQTAATLIQSNYRRYR-QQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMMRR-----------RFLSLKKTAILIQRKYRAHLC--TKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQA---LKQASVVIQQQYQA--NRAAKLQ---RQHYLRQRHSAVI 2390
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Match: DCDC2 (doublecortin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18141]) HSP 1 Score: 51.6026 bits (122), Expect = 1.295e-7 Identity = 24/67 (35.82%), Postives = 43/67 (64.18%), Query Frame = 1
Query: 199 VVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINY 399
VV+++K ++E FL+++T + GA+R++ TP G RI+ L+ + + G YVA + E+ K +NY
Sbjct: 2 VVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQ-EAFKKLNY 67
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Celegans
Match: rpi-1 (pep chromosome:WBcel235:II:13959239:13962417:-1 gene:WBGene00012332.1 transcript:W07G1.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:rpi-1) HSP 1 Score: 61.6178 bits (148), Expect = 1.297e-9 Identity = 31/83 (37.35%), Postives = 51/83 (61.45%), Query Frame = 1
Query: 541 IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQ 789
I ++KNGDR+ +K VI + K M L+ + DR+ L +++YT +G+I+ K++E+GK YVAAS + F + YG+
Sbjct: 37 ISIYKNGDRYHRGVKFVINPRVIKDMEPLLNQVNDRIELSHG--AKKLYTTDGKIVNSIKELEDGKIYVAASAQ-FIPMRYGE 116
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Celegans
Match: rpi-1 (pep chromosome:WBcel235:II:13959239:13962417:-1 gene:WBGene00012332.1 transcript:W07G1.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:rpi-1) HSP 1 Score: 61.6178 bits (148), Expect = 1.400e-9 Identity = 31/83 (37.35%), Postives = 51/83 (61.45%), Query Frame = 1
Query: 541 IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQ 789
I ++KNGDR+ +K VI + K M L+ + DR+ L +++YT +G+I+ K++E+GK YVAAS + F + YG+
Sbjct: 37 ISIYKNGDRYHRGVKFVINPRVIKDMEPLLNQVNDRIELSHG--AKKLYTTDGKIVNSIKELEDGKIYVAASAQ-FIPMRYGE 116
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Celegans
Match: C06C3.3 (pep chromosome:WBcel235:II:9369178:9372485:-1 gene:WBGene00007374.1 transcript:C06C3.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06C3.3) HSP 1 Score: 60.8474 bits (146), Expect = 3.339e-9 Identity = 32/92 (34.78%), Postives = 48/92 (52.17%), Query Frame = 1
Query: 541 IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGR 816
I VF+NGD F +V+ ++ KH V + A+ D LL+ +RR++T G + + D+E YVA PF N+ YGQ +R R
Sbjct: 19 IRVFRNGDMFDHGRILVVTRKQFKHWIVFLDALTD--LLRTATAVRRLFTTQGIPVHHFDDLETNGEYVAVETGPFVNVPYGQARFTLRLKR 108 HSP 2 Score: 51.2174 bits (121), Expect = 3.242e-6 Identity = 27/74 (36.49%), Postives = 42/74 (56.76%), Query Frame = 1
Query: 154 ILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKG 375
I +F+NGD + G+ +VV +K +W FL+ +T L A+R + T G + +DL TNG+YVA+ G
Sbjct: 19 IRVFRNGDMFDHGRILVVTRKQFKHWIVFLDALTDLLRTAT-AVRRLFT-TQGIPVHHFDDLETNGEYVAVETG 90
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Fly
Match: CG14687 (gene:FBgn0037835 transcript:FBtr0082280) HSP 1 Score: 71.2478 bits (173), Expect = 2.905e-14 Identity = 44/114 (38.60%), Postives = 61/114 (53.51%), Query Frame = 1
Query: 1648 EKAAVIIQASFRGYQTRHTLQ----NKVPRKTNNEREKQNG---------------KNQEPTNENKDKEIE-KAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRIL 1929
E AA+ IQA FRGY+ R + N PR+ +R K NG ++Q EN K +E ++ IQAGFRG+ +R K+ AA +IQAGFRG++TR+ L
Sbjct: 18 ESAAIKIQAGFRGYRVRKEIHRSSKNPHPRRNQRQRPKNNGLMENQNNTGNPRPSGEDQHTATENGGKSVEDRSATKIQAGFRGFLVRKKQKIATDAAVKIQAGFRGFKTRKEL 131 HSP 2 Score: 54.299 bits (129), Expect = 1.953e-8 Identity = 54/181 (29.83%), Postives = 78/181 (43.09%), Query Frame = 1
Query: 1000 EIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILK 1542
E AA KIQA FRG++ RKEI ++ +N P P+++ + +PKN E N + E++ T+N ++VE +++ATKIQAGFRG+ R++ K I AA KIQAGFRG+ TR+ LK
Sbjct: 18 ESAAIKIQAGFRGYRVRKEIHRSSKN--PHPRRN-----QRQRPKNNGLMENQNN--TGNPRPSGEDQHT-----ATENGGKSVE--------------------DRSATKIQAGFRGFLVRKKQK--------------------------------IATDAAVKIQAGFRGFKTRKELK 132 HSP 3 Score: 51.2174 bits (121), Expect = 2.658e-7 Identity = 45/151 (29.80%), Postives = 66/151 (43.71%), Query Frame = 1
Query: 1321 AATKIQAGFRGYQTR-----------------QRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVP 1722
AA KIQAGFRGY+ R QR K N ++ + NP+ S + T+ + +++D++A KIQAGFRG+ R+ K +++ AAV IQA FRG++TR L+ P
Sbjct: 20 AAIKIQAGFRGYRVRKEIHRSSKNPHPRRNQRQRPK-NNGLMENQNNTGNPRPSGEDQHTATENGGKSVEDRSATKIQAGFRGFLVRK--KQKIAT-------------------------------DAAVKIQAGFRGFKTRKELKQCEP 136 HSP 4 Score: 47.7506 bits (112), Expect = 4.284e-6 Identity = 22/37 (59.46%), Postives = 28/37 (75.68%), Query Frame = 1
Query: 2074 IQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI 2184
IQAGFRG+ RK+ + +A KIQAGFR +KTRKE+
Sbjct: 95 IQAGFRGFLVRKKQKIATDAAVKIQAGFRGFKTRKEL 131
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Match: dcdc2b (doublecortin domain containing 2B [Source:ZFIN;Acc:ZDB-GENE-051113-124]) HSP 1 Score: 110.153 bits (274), Expect = 5.619e-25 Identity = 66/217 (30.41%), Postives = 120/217 (55.30%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
VK++++++NGD +F G+R VVN++ + L DIT ++ A+R + TP +G R+ L DL +YVA + E K ++Y A + T+S + LA ++ S + + T II+VF+NGD +PA++++I K++ ++ I ++ +L+ +RRI TL G + A+++E G+ YVA +E F+ + Y ++L
Sbjct: 13 VKSVMVYRNGDPFFSGRRFVVNQRQIATMDALLNDITLNIGA-PLAVRTLYTPRYGHRVADLGDLQQGAQYVA-AGSERFKKLDYLSA-GLKKAVEPTQSKT-------LARPNV----SAKWRKVITLPCIIHVFRNGDILSPAMRLIIPRHMLKNLEQILSLISEKAMLRTG-AVRRICTLEGFTVTSAEELETGQCYVAVGSERFKKLPYVEIL 214
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Match: si:dkey-25g12.4 (si:dkey-25g12.4 [Source:ZFIN;Acc:ZDB-GENE-160113-73]) HSP 1 Score: 97.4413 bits (241), Expect = 3.203e-21 Identity = 72/256 (28.12%), Postives = 128/256 (50.00%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRIT-----QNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEY------GQV--LPVIRGGRVPSKRNKIKFLNQMPSPKSD 876
K + +F+NGD ++PG+R ++N++ + ++ FL +T+ + GA+R++ TP +G R+ SL+ L YVA + GE LK ++Y+ N+ P KS S ++P+ + SRI + + +S I VF NGD P +++I ++ + ++V L+ + R+ LNG +R A +++N YVA E F ++ Y G + VI +PS+R + + N P D
Sbjct: 10 KTVTVFRNGDAFYPGRRFIINQRQSVTFDTFLNTVTRDITAPFGAVRNIYTP-NGHRVVSLQQLMHGQMYVA-AGGERLKKMDYN---NITQKPAKKKSES--IQPV---------VHSRIIVPARWKRISNESCTINVFINGDILVPPARILIPKHTLASWENVLAMVTEKVSLRTGA-VHRLCMLNGRPLRGAYELQNNHSYVAVGAEKFRSLPYHLAPSKGAIHSFTVINNDILPSQRKEKQHRNLFAKPGVD 248
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Match: dcdc2b (doublecortin domain containing 2B [Source:ZFIN;Acc:ZDB-GENE-051113-124]) HSP 1 Score: 71.633 bits (174), Expect = 3.916e-14 Identity = 48/158 (30.38%), Postives = 84/158 (53.16%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHM 618
VK++++++NGD +F G+R VVN++ + L DIT ++ A+R + TP +G R+ L DL +YVA + E K ++Y A + T+S + LA ++ ++ T II+VF+NGD +PA++++I +HM
Sbjct: 13 VKSVMVYRNGDPFFSGRRFVVNQRQIATMDALLNDITLNIGAPL-AVRTLYTPRYGHRVADLGDLQQGAQYVA-AGSERFKKLDYLSA-GLKKAVEPTQSKT-------LARPNVSAKWRKVI----TLPCIIHVFRNGDILSPAMRLIIP----RHM 152
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Match: aspm (abnormal spindle microtubule assembly [Source:ZFIN;Acc:ZDB-GENE-050208-620]) HSP 1 Score: 68.5514 bits (166), Expect = 3.570e-11 Identity = 85/368 (23.10%), Postives = 162/368 (44.02%), Query Frame = 1
Query: 1309 KRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQIL-------------KSQVSXXXXXXXXXXXXXXXXXXR--VNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXX----------------XXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI-SEKPVTKPKSLSPE---------EQAQERNDAAAKIQAAFRGHV 2289
++NKAA KIQ +RGY R++L+ K E + + ++ + + + K+++A IQA FR +H +++L + Q+ + Y ++K Q R + + N + A+V+IQ++FR Y R L +K+ + + Q + + EI+ AV+ +QA FRG+++R S+ ++A IQ FR + +R + + A+ RIQA +RG R K+ A IQ+ +R + + F+ ++A IQ +R+++ +++ +E K ++ + ++ Q +N AA IQ+ R H+
Sbjct: 1290 RQNKAAVKIQTLWRGYSAREKLRVLKKE-RHYALQNAAATLIQKTYKAWRVKNLLKKNRSAFVIQAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYLEMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKEL-SKMKQNAVLIQRWFRACVQRKAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRFTAQRHFLCLKRSAIVLQQRYRAKVHGGKFRKEYMALKSASVRIQAMWRGRAER-----KKISQLHRFAKIIQSNYRRHLEQTRFLQMKRAAVVIQRQYRAFRDGQKVHAEYTKIKRAAIILQSAYRGRRIRQELQRKNKAATLIQSVMRAHM 1650 HSP 2 Score: 63.5438 bits (153), Expect = 1.092e-9 Identity = 90/335 (26.87%), Postives = 141/335 (42.09%), Query Frame = 1
Query: 1315 NKAATKIQAGFRGYQTRQR---LKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFR-SYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS 2307
++AAT +QA +R Y R+R +K +I+Q + N K Q +S ++ A +QA +RG R+ L+ Q + K+ +AM+ +AVIIQ+ FR Y +Q + RK + + K+ I IQA FRG+ +R L + +A+ IQA FR YQ R K+ + +Q FR K R + + + NAA+ +Q FRG K R E + K+A IQ+ R S + ++ + EK AA IQ+A+RGH R ++
Sbjct: 2366 HQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQQRKSYLKVRQ--------GALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHKEMV----------KYQAMKLSAVIIQSHFRSY-----IQARADRKNY-------------------QHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARV-----------LQQRFRALKLR-DEHVCQYQQVRNAAVCLQRYFRGMKGR-ELARRSKAARTIQSFLRMSVQRQRFMKEKA------------------AAIAIQSAYRGHFARAQYT 2627 HSP 3 Score: 63.5438 bits (153), Expect = 1.304e-9 Identity = 82/292 (28.08%), Postives = 121/292 (41.44%), Query Frame = 1
Query: 1312 RNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQ---ILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQ-NKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRN---SLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSY 2166
+N AATKIQA R + ++RL I QN KAA KIQ +RGY R+ +LK + A +K + RV N ++A +IQA+FR + + L+ N + Q K Q E+++ + +QA FRG+ R+ +LK R A+ IQ+ FR Y R+ L + Q IQ FR R + + K ++A + +QA FRG+K RK +SA IQ FR +
Sbjct: 1268 KNLAATKIQALARKFILKRRL-----------IRQN---------------------KAAVKIQTLWRGYSAREKLRVLKKERHYALQNAAATLIQKTYKAWRVKNLLKKN-----RSAFVIQAAFRKWHAKKMLERNTAALRIQAWYRMQLCKRQYL-------EMKRKAVCVQAWFRGHLQRSKFQNLKKRHHASVVIQSAFRAYLIRKELSKMKQNAVL-----------IQRWFRACVQR-KAEQKRYFEIKSAVLVLQAAFRGWKVRKSVAQHHRSALVIQTAFRRF 1503 HSP 4 Score: 60.8474 bits (146), Expect = 8.183e-9 Identity = 88/359 (24.51%), Postives = 145/359 (40.39%), Query Frame = 1
Query: 1321 AATKIQAGFRGYQTR--------------------------QRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTR-HTLQNKVPRKTNNEREKQ-NGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVT--------KPKSLSPEE--QAQERNDAAAKIQAAFRG 2283
AA +QA +RG +TR QRL++ ++Q + N Q + EK+S AA +QA +RG TRQ LK M +AA I+QA++R Y R L+ K +R + N Q+ + K + + + +QA +RG ++R +L+++ +AA IQ+ FR ++ + + +A IQ+ FR + + K ++ +AI IQA FRG+ R+ K +++ IQA FR Y+ R ++ + L E Q Q+ +AA +Q FRG
Sbjct: 2272 AALILQAAYRGMKTRHTLKQMHQAATIIQSHVRMRILNLRFQRLRWAVCTVQQ-RFRANRIMRQEMAALQEKKS-------AALILQAAYRGMKTRQTLKQ---------------------------------MHQAATIVQATYRAYSGRKRYLEMKCAAIDIQQRYRAVNAAKQQRKSYLK---VRQGALVLQACYRGRKVRRNLQLQCQAAVLIQSYFRRHK-----------EMVKYQAMKLSAVIIQSHFRSY-IQARADRKNYQHLRKSAIVIQAAFRGHSLRRHLARKQEASVIIQASFRMYQQRSAFKKQRWAARVLQQRFRALKLRDEHVCQYQQVRNAAVCLQRYFRG 2574 HSP 5 Score: 52.373 bits (124), Expect = 2.826e-6 Identity = 86/341 (25.22%), Postives = 134/341 (39.30%), Query Frame = 1
Query: 1321 AATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXR--VNETNDNNNEAMEKAAVIIQASFRGYQTRH---TLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI----SEKPVTKPKSLSPEEQAQERND------AAAKIQAAFRGHVYRR 2298
AA IQ+ FRG + R L+ K Q K Q + Y + AA+ +Q FR T+ + Q + ++ + R + E +K A IIQ +R Y+ RH L+N R R + + Q + + A IT+Q+ +RG R R + R KAA IQA ++ Y+TR + A+ IQ +R R + + + +A+ IQA +RG R++ + +A IQ + +YK RK + + S +R D A IQA+FRG RR
Sbjct: 1761 AAVVIQSAFRGMKVRNYLR---------KSHQAAKVIQAHFRGHSQLKKYRRQQWAASVLQQRFRATVTKNAVMKQYAAIKTATICIQSAFRGMVARKQIAEK--------QKCAKIIQKMYRAYKQRHDYLALRNATIRIQQQYRAVVSARQQH----QRYCSLRAAAITLQSSYRGLRARKEINRRQKAATVIQAAYKMYRTR-----------VPFQAMKLASLVIQRQYRCHLLR-KKARENFLKLKQSAVAIQAIYRGKLARRDLARRHFAATIIQRKYLAYKQRKCFLTLQAAVIFCQQHYRSILLTRHDRKDYLTKRRAVVAIQASFRGMNVRR 2068
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Match: rp1l1a (rp1 like 1a [Source:ZFIN;Acc:ZDB-GENE-120711-1]) HSP 1 Score: 62.003 bits (149), Expect = 3.543e-9 Identity = 58/216 (26.85%), Postives = 95/216 (43.98%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLP-------HHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDI-ENGKFYVAASNEPF 768
VK I +K+GD F G ++ V+K+ ++ L+D+++ + P +R + TP IK LE G Y+ + Y K IN+ + HH+ N+ R KP R D+ S + + I + KN D PA++ I L + S+ V E L+Q + ++R+YTL G I + + + V EPF
Sbjct: 40 VKRITFYKSGDSQFKGVKMAVHKRTFKCFDALLDDLSQKV-PLPFGVRTITTPRGTHSIKHLEQFEDGGCYLCSDR-------RYVKPINMEEVGKRQAVWHHHSHPNNTRRKPSR-----PDEPLSGHQHHHHRHPKRIILVKNSD---PAVRRSIILSRRTARSLRVFTEEISELMQCH--VKRLYTLEGRKIDSIQSLMQCPSVLVCVGREPF 237
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Match: DCDC2 (doublecortin domain containing 2 [Source:NCBI gene;Acc:100493004]) HSP 1 Score: 110.923 bits (276), Expect = 5.562e-25 Identity = 59/217 (27.19%), Postives = 126/217 (58.06%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
VK++ +F+NGD ++ G+R+++++K ++ FL+D+T + GA+R++ TP +G R+ SL+DL YVA + E+ K ++Y +++ + T ++KP+ + ++ +R +N + + +++ NGD P I+++I + + +++ + ++V L+ + + R+YTL G I+ ++ENG+FYVA E F+ + Y ++
Sbjct: 23 VKSVHVFRNGDPFYRGRRMLIHEKRVGTFDVFLKDVTGGVQAPFGAVRNIYTPRNGHRVTSLDDLQPGECYVAGGR-ETFKKLDY---LHIGEIKRKTVDPLSQVKPVSHSRINVS---ARFRKN-FQEPCTVFLVANGDTMNPFIRLLIPRKTLEQWELVLALVTEKVKLR-SGAVHRLYTLEGTPIQNGLELENGQFYVAVGREKFKKLPYSDLI 230
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Match: DCDC2B (doublecortin domain containing 2B [Source:NCBI gene;Acc:100496860]) HSP 1 Score: 88.5817 bits (218), Expect = 5.085e-18 Identity = 87/358 (24.30%), Postives = 166/358 (46.37%), Query Frame = 1
Query: 115 NPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSN-------------IIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRG-GRVPSKRN-------KIKFLNQ-----MPSPKSDKRSQGSSNEE-------PT--DRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNE 1083
+P + L KN+++++NGD + G+++VVN+K +E FL ++T + A+R + TP +G RI L +L G YVA E + ++Y L K +F+ KP R Q +Y K N +I+VF+NGD TP +V++ K +++ + ++ L + +R++ TL+G + ++ +G++YVA +E ++ + Y ++L + G + ++R K+ ++Q P+ + +R + EE P+ + S + +V PK+ K +L+ T + F+ +TR+E+E A+E E
Sbjct: 3 SPSGVQLAPLAKNVVVYRNGDPFHMGRKMVVNEKQFLTFEAFLNEVTSCIQAPV-AVRCIYTPRNGHRITQLGELLNKGHYVA-GGTEKFRKLDY--------LHTEIKQPAFQ-KP-------------REVQQVYPKLNFIERWRKDTQLPCVIHVFRNGDLMTPPFRVLLYPAILKEWELVLSLLTQKLNLN-SGAVRKLCTLDGVSLSNGAELVSGEYYVALGSEKYKCLPYQELLTLNEDKGHLGARRKVAKAGVVKVHSVSQDGYSDSPTREDGRRVYSTGAEENPKLSKHPSKGEESIFYAKPVRVYPKHKAKLNLED--------TTGKEGVFKVKETRQELEGAREVKE 327
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 66.2402 bits (160), Expect = 2.433e-10 Identity = 98/458 (21.40%), Postives = 184/458 (40.17%), Query Frame = 1
Query: 1006 AATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKN--IKPKN-TEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXX----------------XXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI------SEKPVTKPKS----LSPEEQAQERNDAAAKIQAAFRG 2283
AA IQ+AFRG + R+++ + + + ++ + + +N T +Q K++ +++++ ++ Q R + + + + +AT IQA FR ++ + L+ I+Q + KS+ ++ +++S A IQA FRG R++L M KAA IQASFR +Q R + KV + +++ + + + I++AV+ IQ+ +RG+++R L+ + + A RIQ+ ++ ++ R + + A IQA RG R + K +AA IQ+ +R Y RK ++M +++ IQ +R+ K R S K T ++ + Q+ + AAA IQ AF+
Sbjct: 2179 AALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERI------------NHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQS--------AVTIQATFRGMKERKML---------------------------------SIMHKAASTIQASFRMHQCR-SQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVR-----RNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKS 2577 HSP 2 Score: 58.9214 bits (141), Expect = 3.938e-8 Identity = 96/355 (27.04%), Postives = 157/355 (44.23%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPE--------------SLTSEKESDYNIKDKAAA-KIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVT--------KPKSLSPEEQAQERN--DAAAKIQAAFRGHVYRR 2298
KAAT +QAGFRG +TR Q++ I+Q+ S +KS E S+ E +K ++AA IQA +RG R+ LK + + + Q R++ + + A ++AAV+IQ +R Y++ L++K K N + + +++ A +QA +R +R R A + Q FR + R + A KRIQ+ FR K +++AAI IQA ++ + R+E+V ++A IQA FR ++TRK + V+ + L+ ++AQ + AA IQ+AFRG + R
Sbjct: 2543 KAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLR---------HRAAAQIQSLFRMHRQH-VSYLANKQAAVVIQRHYRRYRS-CKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRAR-------VDAVKKYATIRMAVKRIQSAFRARKA------ARDAEKDSAAIVIQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHR 2873
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 65.855 bits (159), Expect = 2.981e-10 Identity = 98/458 (21.40%), Postives = 184/458 (40.17%), Query Frame = 1
Query: 1006 AATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKN--IKPKN-TEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXX----------------XXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI------SEKPVTKPKS----LSPEEQAQERNDAAAKIQAAFRG 2283
AA IQ+AFRG + R+++ + + + ++ + + +N T +Q K++ +++++ ++ Q R + + + + +AT IQA FR ++ + L+ I+Q + KS+ ++ +++S A IQA FRG R++L M KAA IQASFR +Q R + KV + +++ + + + I++AV+ IQ+ +RG+++R L+ + + A RIQ+ ++ ++ R + + A IQA RG R + K +AA IQ+ +R Y RK ++M +++ IQ +R+ K R S K T ++ + Q+ + AAA IQ AF+
Sbjct: 2206 AALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERI------------NHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQS--------AVTIQATFRGMKERKML---------------------------------SIMHKAASTIQASFRMHQCR-SQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVR-----RNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKS 2604 HSP 2 Score: 58.9214 bits (141), Expect = 4.743e-8 Identity = 96/355 (27.04%), Postives = 157/355 (44.23%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPE--------------SLTSEKESDYNIKDKAAA-KIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVT--------KPKSLSPEEQAQERN--DAAAKIQAAFRGHVYRR 2298
KAAT +QAGFRG +TR Q++ I+Q+ S +KS E S+ E +K ++AA IQA +RG R+ LK + + + Q R++ + + A ++AAV+IQ +R Y++ L++K K N + + +++ A +QA +R +R R A + Q FR + R + A KRIQ+ FR K +++AAI IQA ++ + R+E+V ++A IQA FR ++TRK + V+ + L+ ++AQ + AA IQ+AFRG + R
Sbjct: 2570 KAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLR---------HRAAAQIQSLFRMHRQH-VSYLANKQAAVVIQRHYRRYRS-CKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRAR-------VDAVKKYATIRMAVKRIQSAFRARKA------ARDAEKDSAAIVIQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHR 2900
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Match: lrp8 (LDL receptor related protein 8 [Source:Xenbase;Acc:XB-GENE-980035]) HSP 1 Score: 65.855 bits (159), Expect = 3.272e-10 Identity = 98/458 (21.40%), Postives = 184/458 (40.17%), Query Frame = 1
Query: 1006 AATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKN--IKPKN-TEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXX----------------XXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEI------SEKPVTKPKS----LSPEEQAQERNDAAAKIQAAFRG 2283
AA IQ+AFRG + R+++ + + + ++ + + +N T +Q K++ +++++ ++ Q R + + + + +AT IQA FR ++ + L+ I+Q + KS+ ++ +++S A IQA FRG R++L M KAA IQASFR +Q R + KV + +++ + + + I++AV+ IQ+ +RG+++R L+ + + A RIQ+ ++ ++ R + + A IQA RG R + K +AA IQ+ +R Y RK ++M +++ IQ +R+ K R S K T ++ + Q+ + AAA IQ AF+
Sbjct: 2147 AALCIQSAFRGLKVRRDLNAKHAAAALIQRHYKCFLERRRFVLLRNATILTQQRFRMKVHAEQIRQQYLRLKKAVVVLQTAFRGWKERERI------------NHMHYSATVIQAAFRMHKAKDSYHTLRHAAIVIQQRYKANMASKSERKTYLKQRQS--------AVTIQATFRGMKERKML---------------------------------SIMHKAASTIQASFRMHQCR-SQYIKVQWAVHVIQQRFRANKLRDSEKLQYHVIKRAVLCIQSCYRGFKVRKDLEFQHRMATRIQSAYKMHRRRVVYQNMQSAVSLIQTWYRSIATCRQTRAEFLQLRKATILIQAACRGTLVR-----RNIKAMHSAATCIQSFYRMYSQRKYYIMYLQAVCTIQQQYRAKKARDHYFNFYQNSRKAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKS 2545 HSP 2 Score: 58.5362 bits (140), Expect = 6.487e-8 Identity = 96/355 (27.04%), Postives = 157/355 (44.23%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTR---QRLKFNKPEIKQSKISQNPKKSQPE--------------SLTSEKESDYNIKDKAAA-KIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVT--------KPKSLSPEEQAQERN--DAAAKIQAAFRGHVYRR 2298
KAAT +QAGFRG +TR Q++ I+Q+ S +KS E S+ E +K ++AA IQA +RG R+ LK + + + Q R++ + + A ++AAV+IQ +R Y++ L++K K N + + +++ A +QA +R +R R A + Q FR + R + A KRIQ+ FR K +++AAI IQA ++ + R+E+V ++A IQA FR ++TRK + V+ + L+ ++AQ + AA IQ+AFRG + R
Sbjct: 2511 KAATLLQAGFRGMKTRIWIQQMHQAAATIQQAFKSFKERKSYLELKASTILIQRQYRASVLGRAERQKFLKCRSAAICIQAAYRGLREREELKLR---------HRAAAQIQSLFRMHRQH-VSYLANKQAAVVIQRHYRRYRS-CKLEHKQYLKLCNAAIIVQALYRGKKSRKNLRDMHNAATVVQAYYRMHRQRQYYFALQHAVRTTQVRFRANRAR-------VDAVKKYATIRMAVKRIQSAFRARKA------ARDAEKDSAAIVIQAQWKMHTVRREYVKMTEAAVVIQAVFRGHRTRKMLKAMEVSACLIQAWYRSCRLTRLQRAQYLSIRSAAITIQSAFRGMLAHR 2841
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Match: Dcdc2a (doublecortin domain containing 2a [Source:MGI Symbol;Acc:MGI:2652818]) HSP 1 Score: 121.709 bits (304), Expect = 1.182e-28 Identity = 88/357 (24.65%), Postives = 180/357 (50.42%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDK-IESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKP--------KNSEKRSLKKQKNDNEIAATKI----QAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQD 1158
+VK++L+++NGD +F G+RVV+++K +++ FL+++T + GA+R++ TP G RI+ L+ + + G YVA E+ K +NY +++ + + +P+ N ++ I SRI + + ++ I++ NGD +PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N + + S +++ +P NSEK + KQ ++ + I + F+ R E A E E + V +P + +P E+D
Sbjct: 15 VVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGP-EAFKKLNY---LDIGEI---------KKRPMEAVNTEVKPVIHSRINVSARFRKSLHEPCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKRLPYSELLFDKSAMRRPYGQK----ASSLPPMVGSRKSKGSGNYRQSKSTIGSSDNSSPQPLKRKGKKDSNSEKPTKVKQSVKSKTSHQAIPDNGEGIFKAGAERSETRGAAEVQE--DEDTQVEVPVDQRPAEIVDEEED 351
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Match: Dcdc2a (doublecortin domain containing 2a [Source:MGI Symbol;Acc:MGI:2652818]) HSP 1 Score: 116.316 bits (290), Expect = 1.531e-27 Identity = 75/290 (25.86%), Postives = 156/290 (53.79%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDK-IESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKN 993
+VK++L+++NGD +F G+RVV+++K +++ FL+++T + GA+R++ TP G RI+ L+ + + G YVA E+ K +NY +++ + + +P+ N ++ I SRI + + ++ I++ NGD +PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N + + S +++ +P KR KK N
Sbjct: 15 VVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVA-GGPEAFKKLNY---LDIGEI---------KKRPMEAVNTEVKPVIHSRINVSARFRKSLHEPCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKRLPYSELLFDKSAMRRPYGQKA----SSLPPMVGSRKSKGSGNYRQSKSTIGSSDNSSPQPL---KRKGKKDSN 283
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Match: Dcdc2c (doublecortin domain containing 2C [Source:MGI Symbol;Acc:MGI:1915761]) HSP 1 Score: 94.3597 bits (233), Expect = 2.729e-20 Identity = 68/225 (30.22%), Postives = 122/225 (54.22%), Query Frame = 1
Query: 112 KNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLR-LANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEY 783
+ P ++ K IL+++NGDQ++ G++ V +++ N+E LE +T+ + G +R + TP G + L+ L T GKYVA + E K ++Y ++ +P S +LK ++ + + DI K+ SR T S I VF NG F P IKV+I + ++ I ++V +R+++T++G ++ +K++++ FYVAA E F++I Y
Sbjct: 4 RGPYALVDTTPAKTILVYRNGDQFYVGRKFVFSRRRVANFEALLEQLTEQVEVPFG-VRRLYTPTRGHPVLGLDALQTGGKYVAAGR-ERFKKLDY-----IHIVPRKP-SKMRKLKEIKPVVHCDI-KVPSRWQIQSRT-SRYINVFTNGRLFIPPIKVIIPKFSLSDWNSVLAMIGEKVFPLGG--VRKLFTMDGHLLDDSKNLQDNYFYVAAGLETFKSIPY 216
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Match: Dcdc2c (doublecortin domain containing 2C [Source:MGI Symbol;Acc:MGI:1915761]) HSP 1 Score: 94.7449 bits (234), Expect = 3.135e-20 Identity = 68/225 (30.22%), Postives = 122/225 (54.22%), Query Frame = 1
Query: 112 KNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLR-LANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEY 783
+ P ++ K IL+++NGDQ++ G++ V +++ N+E LE +T+ + G +R + TP G + L+ L T GKYVA + E K ++Y ++ +P S +LK ++ + + DI K+ SR T S I VF NG F P IKV+I + ++ I ++V +R+++T++G ++ +K++++ FYVAA E F++I Y
Sbjct: 4 RGPYALVDTTPAKTILVYRNGDQFYVGRKFVFSRRRVANFEALLEQLTEQVEVPFG-VRRLYTPTRGHPVLGLDALQTGGKYVAAGR-ERFKKLDY-----IHIVPRKP-SKMRKLKEIKPVVHCDI-KVPSRWQIQSRT-SRYINVFTNGRLFIPPIKVIIPKFSLSDWNSVLAMIGEKVFPLGG--VRKLFTMDGHLLDDSKNLQDNYFYVAAGLETFKSIPY 216
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Match: Dcdc2b (doublecortin domain containing 2b [Source:MGI Symbol;Acc:MGI:2686212]) HSP 1 Score: 83.5741 bits (205), Expect = 1.019e-16 Identity = 56/221 (25.34%), Postives = 105/221 (47.51%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLP---HHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNI-IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
K IL+++NGD +FPG ++VV ++ P E L ++T ++ A+R + T G + +L DL G+YVA +++ ++ LP H + + ++ R D + Q L + I+VF+NGD +P + + + ++K + ++V LQ + ++ TL G + + NG +YVA E F+ + Y ++L
Sbjct: 2 AKRILVYRNGDAFFPGHQLVVTQRRYPTMEALLYEVTSAVQ-APLAVRVLYTLSDGHPVTNLADLQNGGQYVA---------AGFERFHKIHYLPPGMKHPGGKTRQQHEPPVSQRPCDGV---FGQWLPADAPCYIHVFRNGDLLSPPFSLKLSQTAIQDWDTVLKLLSEKVTLQSGA-VHKLCTLEGLPLSTGTALVNGHYYVAVGEEEFKALPYMELL 208
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9UHG0|DCDC2_HUMAN (Doublecortin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=DCDC2 PE=1 SV=2) HSP 1 Score: 124.02 bits (310), Expect = 1.577e-28 Identity = 90/358 (25.14%), Postives = 180/358 (50.28%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDK-IESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPK---------NSEKRSLKKQ----KNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQD 1158
+VK++L+++NGD ++ G+RVV+++K ++E FL+++T + GA+R++ TP G RI+ L+ + + G YVA + E+ K +NY +++ + + +P+ + N ++ I SRI + + + I++ NGD PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N+ + + S +++ +P NSEK + KQ KN E + F+ R E A E E + V +P + +P E+D
Sbjct: 15 VVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIQSGGNYVAGGQ-EAFKKLNY---LDIGEI---------KKRPMEVVNTEVKPVIHSRINVSARFRKPLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKA----SSLPPIVGSRKSKGSGNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETIPNSDEGIFKAGAERSETRGAAEVQE--DEDTQVEVPVDQRPAEIVDEEED 352
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|D3ZR10|DCDC2_RAT (Doublecortin domain-containing protein 2 OS=Rattus norvegicus OX=10116 GN=Dcdc2 PE=1 SV=1) HSP 1 Score: 122.865 bits (307), Expect = 3.398e-28 Identity = 87/358 (24.30%), Postives = 179/358 (50.00%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDID-------KIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKP--------KNSEKRSLKKQ----KNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQD 1158
+VK++L+++NGD +F G+RVV+++K +++ FL+++T + GA+R++ TP G RI+ L+ + + G YVA + E+ K +NY +++ + + +P+ N ++ + +R + L+ I++ NGD +PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N + + S +++ +P NSEK + KQ KN ++ + F+ R E A E E + V +P + +P E+D
Sbjct: 15 VVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDIFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGQ-EAFKKLNY---LDIGEI---------KKRPMEAVNTEVKPVIHSKINVSARFRKALHEPCT-IFLIANGDLISPASRLLIPRKALNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKRLPYSELLFDKSAMRRPYGQK----ASSLPPMVGSRKSKGSGNYRQSKSTIGSSDNSSPQPLKRKGKKDSNSEKPTKVKQSVKSKNSHQAIPDNDEGIFKAGAERSETRGAAEVQE--DEDTQVEVPVDQRPAEIVDEEED 351
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q5DU00|DCDC2_MOUSE (Doublecortin domain-containing protein 2 OS=Mus musculus OX=10090 GN=Dcdc2 PE=1 SV=2) HSP 1 Score: 121.709 bits (304), Expect = 8.978e-28 Identity = 88/357 (24.65%), Postives = 180/357 (50.42%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDK-IESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKP--------KNSEKRSLKKQKNDNEIAATKI----QAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQD 1158
+VK++L+++NGD +F G+RVV+++K +++ FL+++T + GA+R++ TP G RI+ L+ + + G YVA E+ K +NY +++ + + +P+ N ++ I SRI + + ++ I++ NGD +PA +++I + +++ + +++ L+ + + R+YTL G+++ ++ENG+FYVA + F+ + Y ++L R P + + +P ++S+GS N + + S +++ +P NSEK + KQ ++ + I + F+ R E A E E + V +P + +P E+D
Sbjct: 15 VVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDVFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGP-EAFKKLNY---LDIGEI---------KKRPMEAVNTEVKPVIHSRINVSARFRKSLHEPCTIFLIANGDLISPASRLLIPKKALNQWDHVLQMVTEKITLR-SGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKRLPYSELLFDKSAMRRPYGQK----ASSLPPMVGSRKSKGSGNYRQSKSTIGSSDNSSPQPLKRKGKKDSNSEKPTKVKQSVKSKTSHQAIPDNGEGIFKAGAERSETRGAAEVQE--DEDTQVEVPVDQRPAEIVDEEED 351
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|A2VCK2|DCD2B_HUMAN (Doublecortin domain-containing protein 2B OS=Homo sapiens OX=9606 GN=DCDC2B PE=1 SV=1) HSP 1 Score: 99.7525 bits (247), Expect = 3.250e-21 Identity = 72/276 (26.09%), Postives = 128/276 (46.38%), Query Frame = 1
Query: 136 SVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK---SNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKP 954
S K +++++NGD +FPG ++VV ++ P E FL ++T ++ A+R + TP HG + +L DL G+YVA +++ ++ LPH K S RL+ + D R Q + I+VF+NGD +P + + + ++K + ++V LQ + ++ TL G + K++ G +YVA + F+++ Y ++L VPS + + Q P KS QG+ E ++KP
Sbjct: 5 SPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQ-APLAVRALYTPCHGHPVTNLADLKNRGQYVA---------AGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGA-VCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELL-------VPSP-SLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKP 259
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Match: sp|Q9D1B8|DCD2C_MOUSE (Doublecortin domain-containing protein 2C OS=Mus musculus OX=10090 GN=Dcdc2c PE=2 SV=2) HSP 1 Score: 94.7449 bits (234), Expect = 1.692e-19 Identity = 68/225 (30.22%), Postives = 122/225 (54.22%), Query Frame = 1
Query: 112 KNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLR-LANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEY 783
+ P ++ K IL+++NGDQ++ G++ V +++ N+E LE +T+ + G +R + TP G + L+ L T GKYVA + E K ++Y ++ +P S +LK ++ + + DI K+ SR T S I VF NG F P IKV+I + ++ I ++V +R+++T++G ++ +K++++ FYVAA E F++I Y
Sbjct: 4 RGPYALVDTTPAKTILVYRNGDQFYVGRKFVFSRRRVANFEALLEQLTEQVEVPFG-VRRLYTPTRGHPVLGLDALQTGGKYVAAGR-ERFKKLDY-----IHIVPRKP-SKMRKLKEIKPVVHCDI-KVPSRWQIQSRT-SRYINVFTNGRLFIPPIKVIIPKFSLSDWNSVLAMIGEKVFPLGG--VRKLFTMDGHLLDDSKNLQDNYFYVAAGLETFKSIPY 216
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Match: A0A4E0RKY8 (Uncharacterized protein OS=Fasciola hepatica OX=6192 GN=D915_000661 PE=4 SV=1) HSP 1 Score: 213.386 bits (542), Expect = 1.322e-55 Identity = 194/637 (30.46%), Postives = 296/637 (46.47%), Query Frame = 1
Query: 154 ILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKA----INVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKS-DKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPK------NIK--PKNTEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQ-NKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLK--FNKPE-IKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILK------SQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSL----------------------KVRD--KAAQRIQAGFRGYQTRR 1923
+++ KNGD Y G R+ +N ++ +W+ +E+I L A+R + G+ I L N +YVA+ +GE K NY KA +N +P SN K R + + + RI ++L K I V++NGD FTPAI+VV++ + V +K I+D V+L N+PIR+++TL G++IR + I++ + YVA +E YGQ L +I + P P+S +++S+ + P +S E K KNS S + AA +IQA +RG+ RK + HTV+I + NI P+ TEPHE P ++++ + Q + Q Q ++P+ +S + + AA KIQAGFRGY+TR+ L+ PE ++QS +S +E SD N AA +IQA FRGY TR+ L+ S + Q R + ++ + E + KAA IIQA FRGYQTR L + P + +E G P N+ + E+A IQA +RG+ R +L + D +AA +IQA FR Y+TRR
Sbjct: 26 VIVHKNGDIYNRGHRITINLTHSKSWDSIMEEIRSHLGAYYPALRFLIDNECGSIIVRKSQLGPNKRYVAVPRGEEPKFFNYAKAEQNTLNPRRVP---TSNELFEKYWRKHAKLMLRQPGRICEDLRRKPKTIMVYRNGDSFTPAIRVVLRSSHLTDLDVTLKTIQDFVILMDNKPIRKLFTLEGKLIRRPEQIKDKQTYVATGSESLSLCLYGQNL------------RRIDKTHAQPGPRSINRQSKPRHKKFPVRMDNKSGEQHKPSVKNSTGPS------PVDAAAARIQAGYRGYHFRKTHPEL---------THTVHIARQHQDAPNIHNNPRATEPHEL--TPSTAATRIQAGYRGYQTRKQMHQHDEPKATQSTPHGCNQSQTLPP------DVAAAKIQAGFRGYRTRRELREHHEHPETVQQSNLSN----------LNEIRSDPNY---AATRIQATFRGYQTRRALQEHNSNPSNMKYPLRSRNCNSCSTTQSHTRCHH-DERDPEEVNKAATIIQAGFRGYQTRKHLHS--PHTSTHESHPTGG----PVNK---ENAEQAATRIQAAYRGFSTRKNLHETGPTTGGNMDTNRSITTPTTRYSDPSEAATKIQATFRRYRTRR 601
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Match: A0A267H8Q0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig016684g1 PE=4 SV=1) HSP 1 Score: 175.637 bits (444), Expect = 1.445e-43 Identity = 135/441 (30.61%), Postives = 228/441 (51.70%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTR-IKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK-----------------SNSFRLKPLR--LANRDIDKIESRITQNL---YTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVP-KKHTVYIPKNIKPKNTE--PHEQDKNPKINYSKVKKEEKEIQA------KPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRL 1374
K + +F+NGD + P K+ V+N++ +W+ FLE +T S+NP GA+R++ TP G R I L+ G YVAL++GE K + Y V + H + SN L+P+ + N+ + ++ R + ++S I V++NGD FTPAI V+++ EQ M V+++A+E+RV+L N IR+++ ++G IR +++++ K YVA +EPF + YGQ LP+I G+ +++ IK+L+Q +P+ S+ S + D++ Q+ +T NSE K + +IQA+ RGF+TRK + K PV + V N KPK + P E+ + S VK E QA +P + +N N + + + K +++++ AA IQA Y+TR+++
Sbjct: 40 KCVYIFRNGDVFAPSKKFVLNRRQLRDWDVFLEQVTMSVNPLRGAVRNIVTPKRGRRRIHDLDSFEDKGHYVALARGERFKPMTYVPEAEVGANGSHAETKGSGASPTASPRKPMGSNRVVLEPILPVVHNKKLMSVQPRFGAKMDVISSQSKAIRVYRNGDEFTPAIIVMLRPSEQVSMEVVLRAVEERVVLPNNMAIRKLFDISGRRIREPQELQHEKHYVAGGHEPFLSRPYGQKLPLIVLGKA-ERKSTIKYLSQPITPEKHS-SRKSKQDSQRDQAQQNPRAT-----NSEGGGATKAEKAKAAG--QIQASIRGFETRK-VAAEKRTGGPVTIRPELVNSKANAKPKGAKASPEEKAQAAGTIQSSVKGFEARKQAASKVAQRPIEVKNDAANSKKQKQQQQPQKQQKPMSEEEK-AAAKSIQASVNSYKTRKQV 469
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Match: A0A267EGS0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018380g1 PE=4 SV=1) HSP 1 Score: 174.866 bits (442), Expect = 2.650e-43 Identity = 134/441 (30.39%), Postives = 225/441 (51.02%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTR-IKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK-----------------SNSFRLKPLR--LANRDIDKIESRITQNL---YTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPV---PKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQA------KPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRL 1374
K + +F+NGD + P K+ V+N++ +W+ FLE +T S+NP GA+R++ TP G R I L+ G YVAL++GE K + Y V + H + SN L+P+ + N+ + ++ R + ++S I V++NGD FTPAI V+++ EQ M V+++A+E+RV+L N IR+++ ++G IR +++++ K YVA +EPF + YGQ LP+I G+ +++ IK+L+Q +P+ S+ S + D++ Q+ +T NSE K + +IQA+ RGF+TRK + K PV PK K P E+ + S VK E QA +P + +N P N + + + K +++++ AA IQA Y+TR+++
Sbjct: 40 KCVYIFRNGDVFAPSKKFVLNRRQLRDWDVFLEQVTMSVNPLRGAVRNIVTPKRGRRRIHDLDSFEDKGHYVALARGERFKPMTYVPEAEVGANGSHAETKGSGASPTASPRKPMGSNRVVLEPILPVVHNKKLMSVQPRFGAKMDVISSQSKAIRVYRNGDEFTPAIIVMLRPSEQVSMEVVLRAVEERVVLPNNMAIRKLFDISGRRIREPQELQHEKHYVAGGHEPFLSRPYGQKLPLIVLGKA-ERKSTIKYLSQPITPEKHS-SRKSKQDSQRDQAQQNPRAT-----NSEGGEATKAEKAKAAG--QIQASIRGFETRK-VAAEKRTGGPVTIRPKPANSKANAKPKAAKASPEEKAQAAGTIQSSVKGFEARKQAASKVAQRPIELKNDPANSKKQKQQQQPQKQQKPMSEEEK-AAAKSIQASVNSYKTRKQV 469
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Match: A0A1I8IEM1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 181.03 bits (458), Expect = 2.863e-43 Identity = 149/500 (29.80%), Postives = 251/500 (50.20%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTR-IKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK-----------------SNSFRLKPLR--LANRDIDKIESRITQNL---YTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPV---PKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQA------KPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQN--PKKSQPESLTSEKESDYN-----IKDKAAAKIQAGFRGYHTR 1530
K + +F+NGD + P K+ V+N++ +W+ FLE +T S+NP GA+R++ TP G R I L+ G YVAL++GE K + Y V + H + SN L+P+ + N+ + ++ R + ++S I V++NGD FTPAI V+++ EQ M V+++A+E+RV+L N IR+++ ++G IR +++++ K YVA +EPF + YGQ LP+I G+ +++ IK+L+Q +P+ S+ S + D++ Q+ +T NSE K + +IQA+ RGF+TRK + K PV PK K P E+ + S VK E QA +P + +N N + + + K +++++ AA IQA Y+TR+++ N S ++ + P + Q T+ + Y+ + +AA KIQA +RGY +R
Sbjct: 414 KCVYIFRNGDVFAPSKKFVLNRRQLRDWDVFLEQVTMSVNPLRGAVRNIVTPKRGRRRIHDLDSFEDKGHYVALARGERFKPMTYVPEAEVGANGSHAETKGSGASPTASPRKPMGSNRVLLEPILPVVHNKKLMSVQPRFGAKMDVISSQSKAIRVYRNGDEFTPAIIVMLRPSEQVSMEVVLRAVEERVVLPNNMAIRKLFDISGRRIREPQELQHEKHYVAGGHEPFLSRPYGQKLPLIVLGKA-ERKSTIKYLSQPITPEKHS-SRKSKQDSQRDQAQQNPRAT-----NSEGGGATKAEKAKAAG--QIQASIRGFETRK-VAAEKRTGGPVTIRPKPANSKANAKPKAAKASPEEKAQAAGTIQSSVKGFEARKQAASKVAQRPIELKNDAANSKKQKQQQQPQKQQKPMSEEEK-AAAKSIQASVNSYKTRKQVLSN----SNSPVTSHAGPGQQQHNHATTYRAEQYDGYEDPMYHQAATKIQATYRGYRSR 898
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Match: A0A267GFD5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018380g2 PE=4 SV=1) HSP 1 Score: 172.555 bits (436), Expect = 2.192e-42 Identity = 133/441 (30.16%), Postives = 224/441 (50.79%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTR-IKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTK-----------------SNSFRLKPLR--LANRDIDKIESRITQNL---YTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPV---PKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQA------KPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRL 1374
K + +F+NGD + P K+ V+N++ +W+ FLE +T S+NP GA+R++ TP G R I L+ G YVAL++GE K + Y V + H + SN L+P+ + N+ + ++ R + ++S I V++NGD FTPAI V+++ EQ M V+++A+E+RV+L N IR+++ ++G IR +++++ K YVA +EPF + YGQ LP+I G+ +++ IK+L+Q +P+ S+ S + D++ Q+ +T NSE K + +IQA+ RGF+TRK + K PV PK K P E+ + S VK E QA +P + +N N + + + K +++++ AA IQA Y+TR+++
Sbjct: 40 KCVYIFRNGDVFAPSKKFVLNRRQLRDWDVFLEQVTMSVNPLRGAVRNIVTPKRGRRRIHDLDSFEDKGHYVALARGERFKPMTYVPEAEVGANGSHAETKGSGASPTASPRKPMGSNRVLLEPILPVVHNKKLMSVQPRFGAKMDVISSQSKAIRVYRNGDEFTPAIIVMLRPSEQVSMEVVLRAVEERVVLPNNMAIRKLFDISGRRIREPQELQHEKHYVAGGHEPFLSRPYGQKLPLIVLGKA-ERKSTIKYLSQPITPEKHS-SRKSKQDSQRDQAQQNPRAT-----NSEGGGATKAEKAKAAG--QIQASIRGFETRK-VAAEKRTGGPVTIRPKPANSKANAKPKAAKASPEEKAQAAGTIQSSVKGFEARKQAASKVAQRPIELKNDAANSKKQKQQQQPQKQQKPMSEEEK-AAAKSIQASVNSYKTRKQV 469
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000050955.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:19696740:19722139:-1 gene:ENSAMXG00000037587.1 transcript:ENSAMXT00000050955.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.375 bits (259), Expect = 1.898e-23 Identity = 68/223 (30.49%), Postives = 117/223 (52.47%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDI-DKIESRITQNLYTKSNI-----IYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLP 798
K+IL+++NGD ++PGK+ V+N++ T +E FL +T+ + GA+R + TP G RI+SLE S +YVA + E LK I+Y H N +P R+ N+ I + S+I + NI I VF NGD P ++++ ++ + ++V L+ + + R++TL+G + +++N ++YVA E F + Y Q +P
Sbjct: 17 KSILVYRNGDAFYPGKKFVINQRQTATFESFLGSVTRGIEAPFGAVRHIYTPREGHRIRSLEQFSHGERYVA-AGAERLKNIDY----------LHITPN----RPQRMKNKQIRPVVHSKIIVPARWRKNIDEPCTINVFANGDILVPPARILLPKYTLNSWESVLAMVTEKVHLR-SGAVHRLFTLDGTPLLGTAELKNNQYYVAVGMEKFRHKPYVQNIP 223
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Match: dcdc2b (doublecortin domain containing 2B [Source:ZFIN;Acc:ZDB-GENE-051113-124]) HSP 1 Score: 103.219 bits (256), Expect = 4.362e-23 Identity = 64/217 (29.49%), Postives = 117/217 (53.92%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
VK++++++NGD +F G++ +VN++ E FL D+T S+ AIR + TP HG R+ L+ L +YVA + E K I+Y S + P+++ +R + R + T II VF+NGD + A++ +I K++ ++ I ++ +L+ +RR+ TL+G + A+++E+G+ YVA E F+ + Y ++L
Sbjct: 13 VKSVMVYRNGDPFFTGRKFIVNQRQISTMEAFLNDVTVSIGA-PLAIRTLYTPRHGHRVPDLDHLQQGAQYVA-AGFERFKKIDY-------------FSVGLKRAPVKVLSRPNVSAKWR---KVITLPCIINVFRNGDILSSAMRFIIPRNMLKNLEQILSLISEKAMLRTG-AVRRLCTLDGVTVASAEELESGQCYVAVGTERFKKLPYVELL 210
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000055346.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:19700301:19722115:-1 gene:ENSAMXG00000037587.1 transcript:ENSAMXT00000055346.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 89.7373 bits (221), Expect = 3.451e-19 Identity = 60/217 (27.65%), Postives = 110/217 (50.69%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLP 798
K+IL+++NGD ++PGK+ V+N++ T +E FL +T+ + GA+R + TP G RI+SLE S +YVA + E LK I ++P+ + ++ I + +R +N+ I VF NGD P ++++ ++ + ++V L+ ++TL+G + +++N ++YVA E F + Y Q +P
Sbjct: 9 KSILVYRNGDAFYPGKKFVINQRQTATFESFLGSVTRGIEAPFGAVRHIYTPREGHRIRSLEQFSHGERYVA-AGAERLKNI---------------------IRPV-VHSKII--VPARWRKNIDEPCTI--VFANGDILVPPARILLPKYTLNSWESVLAMVTEKVHLRSG--AVHLFTLDGTPLLGTAELKNNQYYVAVGMEKFRHKPYVQNIP 196
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000039996.1 (doublecortin domain containing 2 [Source:NCBI gene;Acc:103026450]) HSP 1 Score: 91.2781 bits (225), Expect = 7.230e-19 Identity = 61/222 (27.48%), Postives = 115/222 (51.80%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKP-----LRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
VK+IL+++NG+ +RVV+++K + E L +++ G R + TP G R+ +L+D+ G YVA E+ K I+Y + N N T+SN LKP + ++ R + I T I++ NGD PA+++++ + +++ + +++ L++ +R +YT +G + K++ENG+FYVA + F+ + Y +L
Sbjct: 14 VKSILVYRNGEHGRGPRRVVLHEKRVSSLEGLLRELS-------GGTRRLHTP-QGHRVGALQDIQHRGAYVAAGT-ETFKKIDYLQIGNRNK--QTTQSNGV-LKPVPQNRINVSARFLKPINEPCT---------IFIVANGDVLNPAVRLLVHSRLLGQFERILEMVTEKMGLRVLGGVRSLYTFDGISVMDGKELENGQFYVAVGRDKFKRLPYADLL 214
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Match: ENSAMXT00000036226.1 (pep primary_assembly:Astyanax_mexicanus-2.0:5:19209457:19235971:1 gene:ENSAMXG00000030872.1 transcript:ENSAMXT00000036226.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.559 bits (179), Expect = 7.749e-13 Identity = 123/491 (25.05%), Postives = 198/491 (40.33%), Query Frame = 1
Query: 943 KVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVY----------IPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQA--KPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKV-PRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGY--QTRRILXXXXXXXXXXXXXXXXXXXR--------------IQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEF-VMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKS----------LSPEEQAQERNDAAAKIQAAFRGHVYR 2295
K+ K +R QK AA +QAA+RG + RKE +K +E + + +Y + + + H + K + + K++ +QA + +T+ + N+ S AAT IQ + Y+ R+ KF + + +K + + ++ Y K AA IQA FRG R+ + Q+ KAA+ IQA R ++T+ Q + KT R + N +E K K + A + +QA FRG + R++LK + KAA IQ+ +R + QTR + + + AA++ +QA FRG + R +E Q AA IQA FR ++ R ++ M+V SA IQ FR+Y K+ E+ ++ KS S + + AA IQAA R H +R
Sbjct: 279 KLLAKQQRQRYCSMQK-----AAITLQAAYRGMRVRKEAQKRQEAATVLQAWYRMYRVKMAFQAMRLAAVLVQRRYRCHLERKEARERFVKLRHSAIVVQAVFRGNRTRREIGNLHS---------------------AATVIQRKYLAYKERK--KFLSV---RDTVVHCQQKWRAVLASRQQLKAYLAKRSAAIAIQAAFRGMKVRR--RVQIE-------------------------------RKAAITIQAHVRMHKTKVYYQRLLWATKTVQRRYRANQMMKEEMKSLKQKRM--ATVVLQAAFRGMKARHTLKQKHKAAIVIQSAYRAHCAQTRYLCMRYAAVAIQQRYRATLAARKQREHFLQLRCASISLQACFRGQRAR-----REIGLQHQAAKVIQASFRSHRERTKYQAMRV-SAMIIQRHFRAYIVAKDNRERYLSLRKSAILIQTLFRGYSVRHHIAKMHKAATTIQAALRMHKHR 697 HSP 2 Score: 56.6102 bits (135), Expect = 1.254e-7 Identity = 67/251 (26.69%), Postives = 111/251 (44.22%), Query Frame = 1
Query: 1642 AMEKAAVIIQASFRGYQTR-----HTLQNKVPRKTNNEREKQN-------------GKNQEPTNENKDKE----IEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKS-------LSPEEQAQ---ERNDAAAKIQAAFRGHVYRR 2298
+M+KAA+ +QA++RG Q R L K+ ++ +++N G+ + + ++ ++KA IT+QA +RG R+R + R +AA +QA +R Y+ + + +R +A R K R ++AI +QA FRG +TR+E +A IQ + +YK RK+ T L+ +Q + + AA IQAAFRG RR
Sbjct: 218 SMQKAAITLQAAYRGMQARKRIAEMQLAAKIIQRKYRAYKQRNEYCALKQVTIVIQGRYRAKLLAKQQRQRYCSMQKAAITLQAAYRGMRVRKEAQKRQEAATVLQAWYRMYRVKMAFQAMRLAAVLVQRRYRCHLERKEARERFVKLR------------HSAIVVQAVFRGNRTRREIGNLHSAATVIQRKYLAYKERKKFLSVRDTVVHCQQKWRAVLASRQQLKAYLAKRSAAIAIQAAFRGMKVRR 456
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007117.1 (pep scaffold:Pmarinus_7.0:GL477366:363732:368225:-1 gene:ENSPMAG00000006438.1 transcript:ENSPMAT00000007117.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 48.1358 bits (113), Expect = 2.813e-6 Identity = 44/191 (23.04%), Postives = 93/191 (48.69%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLN-----PRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGE 702
K + ++NGD+YF G V+ +++ LED+T++L P+ +R + T R+ +L++L YV S E + ++Y K +N N + KS+ + + ++R ESR + + ++ V ++G + A+++++ + ++ I D + L ++R+YTL+G+
Sbjct: 56 AKKVRFYRNGDRYFRGIVYAVSPDRFRSFDALLEDLTRTLTDNVNLPQ--GVRAIYTCDGSRRMLTLDELVEGESYVCASN-EPYRRLDYTKTLNPN-WSVNIKSSGGKAQSAAGSSRYTAGSESRD----FIRPKLVTVIRSGVKPRKAVRILLNKKTAHSFDQVLTDITDAIKLDTG-VVKRLYTLDGK 237
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO46255 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ95]) HSP 1 Score: 104.76 bits (260), Expect = 6.227e-24 Identity = 80/270 (29.63%), Postives = 136/270 (50.37%), Query Frame = 1
Query: 154 ILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKP-----LRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEP-FENIEYGQVLPVIRGGRVPSKRN-KIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVEST 942
+ ++KNG+ FPGK+VVVN + N + L+ IT+ + + A R ++TP G +I LE + G+YV E+ K +NY + P T + P L+++ R + ++ N+ I+V+KNGD T ++KV + +E K M + I ++V LQ +R +YT++GE ++ ++ N YVAA +E F+ + Y + RVP+K + K K L++ +P K S G N + +DR S +
Sbjct: 6 VTIYKNGEPKFPGKKVVVNPRQVRNMDACLDKITREMKLKTAA-RSLKTPTGGHKIDKLEKIEPGGQYVVCGL-EAFKRLNYMEIKPEGMRP--TPRKEIEITPVKHSRLQMSGRARKRADAEKGNNMG-----IFVYKNGDALTSSVKVHLSDRELKSMDKVCDFITNKVHLQTG-AVRILYTMDGECVKDPSELSNSAKYVAAGHEKRFKRVAYNDSSVLSPRSRVPTKTHFKAKNLSKT-TPNRTKPSHGRKNSDRSDRKMSSTTGS 264
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO47258 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RME3]) HSP 1 Score: 57.7658 bits (138), Expect = 1.798e-10 Identity = 31/86 (36.05%), Postives = 52/86 (60.47%), Query Frame = 1
Query: 136 SVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKII 393
+VL I ++KNGD + GK +V+N +Y ++ FL++ T+ + A+R + TP IKS+++L GKYVA+ + E+ K I
Sbjct: 6 AVLATRITIYKNGDPFSKGKDIVINHRYYRTFDTFLDNATRYAKCSD-AVRKIVTPQGRHHIKSVDELQNGGKYVAIGR-EAFKKI 89
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO35044 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMM4]) HSP 1 Score: 55.4546 bits (132), Expect = 6.433e-10 Identity = 35/77 (45.45%), Postives = 50/77 (64.94%), Query Frame = 1
Query: 1321 AATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNI---KDKAAAKIQAGFRGYHTRQILK 1542
AAT+IQA FRGYQTR RL+ E K++ S +PKK ++ E+ Y++ + KAA IQAG+RGY +R+ +K
Sbjct: 1 AATQIQAHFRGYQTRARLQEGSGESKKAG-SDSPKK-----VSGEQRKAYSVSGEQQKAATAIQAGYRGYRSRKKVK 71 HSP 2 Score: 45.8246 bits (107), Expect = 1.683e-6 Identity = 31/80 (38.75%), Postives = 39/80 (48.75%), Query Frame = 1
Query: 1654 AAVIIQASFRGYQTRHTLQ----------NKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLK 1863
AA IQA FRGYQTR LQ + P+K + E+ K + E +KA IQAG+RGYR R +K
Sbjct: 1 AATQIQAHFRGYQTRARLQEGSGESKKAGSDSPKKVSGEQRKAY---------SVSGEQQKAATAIQAGYRGYRSRKKVK 71
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Nematostella
Match: EDO26163 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TCQ2]) HSP 1 Score: 51.6026 bits (122), Expect = 2.124e-8 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 1
Query: 154 ILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYV 360
+ ++KNG+ FPGK+VVVN + N + L+ IT+ + + A R ++TP G +I LE + G+YV
Sbjct: 6 VTIYKNGEPKFPGKKVVVNPRQVRNMDACLDKITREMKLKTAA-RSLKTPTGGHKIDKLEKIEPGGQYV 73
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Match: DCDC2 (doublecortin domain-containing protein 2 [Source:NCBI gene;Acc:101158630]) HSP 1 Score: 102.834 bits (255), Expect = 6.958e-23 Identity = 67/234 (28.63%), Postives = 122/234 (52.14%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINY-----DKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL---PVIRGGRV 819
+VKNI +F+NGD Y+ +R+VVN+K N+E L ++T + GA+R + TP G ++ +E L + +YVA + E K ++Y K + +L TK L P R++ + +R + + + I+V NGD PA++++I + +++ I +++ L++ +R +YT G + + +E+G+ YVA E F+ + Y +L P RG R+
Sbjct: 13 VVKNIFMFRNGDPYYEARRIVVNEKRVCNFETLLREVTGGIQAPFGAVRTIYTPRGGHKVDCMESLHSGEQYVAAGR-ERFKRLDYVQIGTRKKRMMQTLTTPTKP----LPPNRIS------VSARFLKPI-KEPCPIFVVANGDILNPAMRLLIHQRMLGQFDRILEMITEKMGLRVLGGVRSLYTCEGLQVTDGEKLESGQLYVAVGRERFKKLLYSDLLFSKP--RGARI 232
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Match: dcdc2b (doublecortin domain-containing protein 2 [Source:NCBI gene;Acc:101170886]) HSP 1 Score: 97.0561 bits (240), Expect = 5.337e-21 Identity = 62/219 (28.31%), Postives = 109/219 (49.77%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFR--LKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVL 795
VK++++++NGD + G+R VVN++ E FL ++T+S+ A+R + TP G R+ L+DL T +YVA + E K ++Y A V P + + KP A + II+VF+NGD ++ +I ++ + ++ I ++V L+ +RR+ +L G + A ++E G YVA E F+ + Y +L
Sbjct: 14 VKSVVVYRNGDPFHTGRRFVVNQRQVATMEAFLNEVTRSIRA-PLAVRTLYTPKQGHRVTDLQDLQTGAQYVA-AGSERFKKLDYLNA-GVKKQPASREETQVKGVQKPHVTAK----------WREFVPAPCIIHVFRNGDLLCAPLRFLIPRSMRQDLEQILCVISEKVNLRTG-AVRRLCSLEGMTVSSAGELETGHCYVAVGTERFKKLPYEALL 218
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Match: ENSORLT00000034154.1 (RP1, axonemal microtubule associated [Source:NCBI gene;Acc:101163696]) HSP 1 Score: 57.3806 bits (137), Expect = 6.670e-8 Identity = 65/229 (28.38%), Postives = 104/229 (45.41%), Query Frame = 1
Query: 139 VLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTP--YHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLP--HHTKSNS--------FRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRV--LLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEY 783
++ K + +K+GD F G R+V+N + +E L+ ++K + P +R++ TP HG I +LED +GK S +K IN A+ LP +H + S RL P R NR + I R + L VF+NGD P+++ + L K + ++I D + L+Q + + ++YT +G R I VA EPF Y
Sbjct: 33 IISKRVCFYKSGDPQFNGLRIVINNRTFKTFEALLDSLSKKV-PLPFGVRNITTPRGVHG--IHTLEDFE-DGKSYICSDSRKVKPINL--ALARKKLPPWYHARPVSSRRQTVQQARLFPGRGINRQ-EAIAVRTPKKL-------VVFRNGD---PSVRHTVVL--HKKTTPSYESILDYISELMQFH--VVKLYTPDG---RRVSLIMCSGTVVAVGREPFRPAVY 237
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Match: dclk1a (serine/threonine-protein kinase DCLK1 [Source:NCBI gene;Acc:101167140]) HSP 1 Score: 56.225 bits (134), Expect = 7.490e-8 Identity = 53/213 (24.88%), Postives = 106/213 (49.77%), Query Frame = 1
Query: 145 VKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPY--HGT-RIKSLEDLSTNGKYVALSKGESLKIINYDKAINVN-SLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGK-FYVAASNEPF 768
K + ++NGD+YF G ++ ++ L D+T+SL+ + VRT Y G+ +I S++ L G YV S E+ K ++Y K +N N S+ S S R P L++ ++ R ++ + + ++ V ++G + A+++++ + ++ I D + L + +++IYTL G+++ +D + +VA E F
Sbjct: 49 AKKVRFYRNGDRYFNGIVYAISADRFRTFDALLADLTRSLSDNVNLPQGVRTIYALDGSKKISSVDQLVEGGSYVC-SSTEAYKKLDYTKNVNPNWSVNVKASSTSVR-GPASLSSSKASALDGRENKD-FIRPKLVTVVRSGVKPRKAVRILLNKKTAHSYEQVLTDITDAIKLD-SGVVKKIYTLEGKLVSCLQDFFGDEDIFVACGPEKF 257
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Match: dclk1b (serine/threonine-protein kinase DCLK1 [Source:NCBI gene;Acc:101155370]) HSP 1 Score: 56.225 bits (134), Expect = 1.291e-7 Identity = 47/207 (22.71%), Postives = 101/207 (48.79%), Query Frame = 1
Query: 148 KNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPY---HGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDI--ENGKFYVAA 753
K I ++NGD+YF G ++ + + + L D+T+ L+ + VRT Y T+I S++ L YV S E K ++Y K +N N + S R P +N+ E+R +++ + + ++ + ++G + A+++++ + ++ I D + L + ++R+YT++G+++ +D E+ F+
Sbjct: 52 KKIRFYRNGDRYFKGIVYAISSERFGSLDALLADLTRCLSDNVNLPQGVRTIYTIDGVTKIASMDQLVEGESYVCASI-EPFKKLDYTKNVNPNWSLGAKTAASVRDPPFLCSNK-AGSPETRESKD-FIRPKLVTIVRSGVKPRKAVRILLNKKTAHSFEQVMTDITDAIKLD-SGVVKRLYTVDGKMVTCLQDFFGEDDIFFACG 254
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000038137.1 (SMESG000038137.1) HSP 1 Score: 952.584 bits (2461), Expect = 0.000e+0 Identity = 555/564 (98.40%), Postives = 559/564 (99.11%), Query Frame = 1
Query: 616 MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS 2307
MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENN+PV KKHTVYIPK+IKPKNTE HEQDKNPKINYSKVKKEEKEIQAKPQKTQNK RNVESKTTNPKNTNPNKTNADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSPKPYKAPEKKNEKKQEPKRVNETNDNNN+AME AAVIIQASFRGYQTRHTLQNKVPRKTNNE EKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILKQNNQKKQENDNNKEEAAKRIQAGFRGFKTRKEIKNKEK+NQENAAIKIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS
Sbjct: 1 MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNKPVSKKHTVYIPKSIKPKNTEHHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKSRNVESKTTNPKNTNPNKTNADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSPKPYKAPEKKNEKKQEPKRVNETNDNNNKAMETAAVIIQASFRGYQTRHTLQNKVPRKTNNEPEKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILKQNNQKKQENDNNKEEAAKRIQAGFRGFKTRKEIKNKEKENQENAAIKIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS 564
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000040481.1 (SMESG000040481.1) HSP 1 Score: 412.149 bits (1058), Expect = 6.871e-139 Identity = 207/208 (99.52%), Postives = 207/208 (99.52%), Query Frame = 1
Query: 616 MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNK 1239
MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTE HEQDKNPKINYSKVKKEEKEIQAKPQKTQNK
Sbjct: 1 MSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSPKSDKRSQGSSNEEPTDRSTQSVESTKVKPKNSEKRSLKKQKNDNEIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEHHEQDKNPKINYSKVKKEEKEIQAKPQKTQNK 208
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000040480.1 (SMESG000040480.1) HSP 1 Score: 365.155 bits (936), Expect = 3.919e-121 Identity = 221/221 (100.00%), Postives = 221/221 (100.00%), Query Frame = 1
Query: 1645 MEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILXXXXXXXXXXXXXXXXXXXRIQAGFRGFKTRXXXXXXXXXXXXXXXXXIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS 2307
MEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILKQNNQKKQENDNNKEEAAKRIQAGFRGFKTRKEIKNKEKKNQENAAIKIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS
Sbjct: 1 MEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILKQNNQKKQENDNNKEEAAKRIQAGFRGFKTRKEIKNKEKKNQENAAIKIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRRDHS 221 HSP 2 Score: 97.8265 bits (242), Expect = 1.170e-22 Identity = 88/256 (34.38%), Postives = 121/256 (47.27%), Query Frame = 1
Query: 1318 KAATKIQAGFRGYQTRQRLKFNKP-EIKQSKISQNPKKSQPESLTSEKE------------------SDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRR------ILXXXXXXXXXXXXXXXXXXXRIQAGFRG 2010
KAA IQA FRGYQTR L+ P + + QN K +P + +KE + ++DKAA +IQAGFRGY TR+ILK + + NDNN E+AA IQA FRG++TR ++NK + N A I IQAGFRGY+ R ++ K+A++IQAGFR Y+TR+ + K + +E + +AA +IQA FRG
Sbjct: 3 KAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSLKVRDKAAQRIQAGFRGYQTRRILKQ-------------------NNQKKQENDNNK---EEAAKRIQAGFRGFKTRKEIKNKEKKNQEN-----------------------AAIKIQAGFRGYKTRKEFVMKVKSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRG 213 HSP 3 Score: 75.0998 bits (183), Expect = 6.845e-15 Identity = 98/325 (30.15%), Postives = 135/325 (41.54%), Query Frame = 1
Query: 1000 EIAATKIQAAFRGFQTRKEIEKAKENNEPVPKKHTVYIPKNIKPKNTEPHEQDKNPKINYSKVKKEEKEIQAKPQKTQNKPRNVESXXXXXXXXXXXXXXADDKRNKAATKIQAGFRGYQTRQRLKFNKPEIKQSKISQNPKKSQPESLTSEKESDYNIKDKAAAKIQAGFRGYHTRQILKSQVSXXXXXXXXXXXXXXXXXXRVNETNDNNNEAMEKAAVIIQASFRGYQTRHTLQNKVPRKTNNEREKQNGKNQEPTNENKDKEIEKAVITIQAGFRGYRIRNSL-----------------KVRDKAAQRIQAGFRGYQTRR 1923
E AA IQA+FRG+QTR ++ VP+K K KN EP ++K+ +I + + IQA + + RN + R+KAA +IQAGFRGYQTR+ LK QN +K Q E+D N K++AA +IQAGFRG+ TR+ +K++ + E AA+ IQA FRGY+TR KV K+ IQAGFR Y+ R + + R+ AA +IQA FRG+ RR
Sbjct: 2 EKAAVIIQASFRGYQTRHTLQ------NKVPRKTNNEREKQ-NGKNQEPTNENKDKEIEKAVI-----TIQAGFRGY--RIRN-----------------SLKVRDKAAQRIQAGFRGYQTRRILK------------QNNQKKQ--------ENDNN-KEEAAKRIQAGFRGFKTRKEIKNKEK----------------------------KNQENAAIKIQAGFRGYKTRKEFVMKV----------------------------KSAEKIQAGFRSYKTRKEISEKPVTKPKSLSPEEQAQERNDAAAKIQAAFRGHVYRR 218
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000040482.1 (SMESG000040482.1) HSP 1 Score: 253.447 bits (646), Expect = 1.680e-79 Identity = 138/143 (96.50%), Postives = 142/143 (99.30%), Query Frame = 1
Query: 46 MTTARVXXXXXXXXXXXXXXXXKNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHHTKSNSFRLKPLRL 474
MTTARVNNENYYEDENEN HENKNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPH+TKSNSFRLKP+++
Sbjct: 1 MTTARVNNENYYEDENENAHENKNPDNTNESVLVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNSLPHNTKSNSFRLKPVKI 143
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Match: SMESG000059704.1 (SMESG000059704.1) HSP 1 Score: 174.481 bits (441), Expect = 1.920e-47 Identity = 95/274 (34.67%), Postives = 157/274 (57.30%), Query Frame = 1
Query: 142 LVKNILLFKNGDQYFPGKRVVVNKKYTPNWECFLEDITKSLNPRNGAIRDVRTPYHGTRIKSLEDLSTNGKYVALSKGESLKIINYDKAINVNS---------LPHHTKSNSFRLKPLRLANRDIDKIESRITQNLYTKSNIIYVFKNGDRFTPAIKVVIKLQEQKHMSVLVKAIEDRVLLQINRPIRRIYTLNGEIIRYAKDIENGKFYVAASNEPFENIEYGQVLPVIRGGRVPSKRNKIKFLNQMPSP---KSDKRSQGSSNEEPTDRSTQ 927
VKN+ + +NGD + +R V NKK W+ FLED+T +LNPR G IR + TP G++I++ +++ N YVAL+ GE L++I Y + + LP S + + P + R ++ RI + + I +F+NGD +T AI V++K E K M +++K + ++V+L + PIRR++T++GE I +E+ K Y+A +EPF YGQ LP I G P K+ +I++LN + +P K K+++ SN+ T +S++
Sbjct: 42 FVKNVYIHRNGDMFSSSRRFVYNKKQLRTWDAFLEDLTSALNPRTGPIRSIHTPQTGSKIQTFDEIQPNSNYVALASGEKLQMIGYLRLLQEQEAAKKRRNYHLPFQGASEASSV-PSTVQRR--FQVSGRIKYEMQKRGKTICIFRNGDEYTRAICVMLKYSELKSMDLVLKVVGEKVILPTSLPIRRLFTMDGEAISDPDQLEDNKSYIALGHEPFVPCLYGQTLPNIICG--PKKQERIRYLNSVTTPTPGKQRKKNKSHSNDSMTPKSSR 310 The following BLAST results are available for this feature:
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 1
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Doublecortin domain-containing protein 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Doublecortin domain-containing protein 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30002064 ID=SMED30002064|Name=Doublecortin domain-containing protein 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2532bpback to top protein sequence of SMED30002064-orf-1 >SMED30002064-orf-1 ID=SMED30002064-orf-1|Name=SMED30002064-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=755bp MTTARVNNENYYEDENENTHENKNPDNTNESVLVKNILLFKNGDQYFPGKback to top Annotated Terms
The following terms have been associated with this transcript:
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