Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

Overview


Name	Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
Smed ID	SMED30002042
Length (bp)	1310

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (SMED30002042) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (SMED30002042) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30002042

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30002042	SMESG000021295.1	SmedASXL_010845	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
protonephridia	SMED30002042	SMESG000021295.1	dd_Smed_v4_9114_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30002042	SMESG000021295.1	dd_Smed_v4_9114_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30002042	SMESG000021295.1	dd_Smed_v4_9114_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002042	SMESG000021295.1	Contig41699	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30002042	SMESG000021295.1	Contig41699	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
head region	SMED30002042	SMESG000021295.1	dd_Smed_v6_9114_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30002042	SMESG000021295.1	dd_Smed_v4_9114_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

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Homology

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BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494])

HSP 1 Score: 109.383 bits (272), Expect = 1.974e-25
Identity = 66/287 (23.00%), Postives = 133/287 (46.34%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L++E  + D        A+H+A   G  EVVK+L+    N+  +      P+++     ++E+++ L+    D  +  ++ T++ F  L     +  + +        T   V+   +HIA  K       L++ ND N     K  + P+H+A  YG++++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H   +SGH  +V+ L+     +  +  +G +PL +A + ++  CV ++L
Sbjct:   56 NGLNALHLASKEGHVEVVSELLQREA-NVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLL----DNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 337

HSP 2 Score: 96.2857 bits (238), Expect = 6.564e-21
Identity = 58/255 (22.75%), Postives = 111/255 (43.53%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A ++   +   +L+    N + E      P+HI    GNI +  LL+                N     D  + N             P+H+A  +G+ N+VKL++D    +    +D   P+H     GH  ++++LL+      ++ K    P+H A +  H+  V++L+++N   +    +    +H A   GH  + K L+  K N   + ++G TPL +A + N    ++++L
Sbjct:  175 LLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLL----------------NRAAAVDFTARN----------DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL 403

HSP 3 Score: 84.3445 bits (207), Expect = 5.586e-17
Identity = 52/231 (22.51%), Postives = 107/231 (46.32%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIANIP-----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
            S F P      +H+A   G + V  +L+N+   ++     +I P+H+    GN  +++LL+    + D ++   +           E++ ++  + +  I +       P+H+A    H N V+L++ ++  +     D    +HVA   GH  + K+LL+       +      P+H ACK   ++++ +L+++  + ++       PIH A   GHV+IV  L+H+  +
Sbjct:  217 SGFTP------LHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 441

HSP 4 Score: 80.1073 bits (196), Expect = 1.268e-15
Identity = 40/146 (27.40%), Postives = 73/146 (50.00%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A   GH       I N  ++   +++    +H+A   GHV+++  LL+     +   K     +H A   G  E+V++LV N  N  +Q+     P++ A +  H+++VKFL+ N  +  +   DG TPL +AL+  ++  V ++L
Sbjct:   31 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 176

HSP 5 Score: 71.633 bits (174), Expect = 8.451e-13
Identity = 42/204 (20.59%), Postives = 93/204 (45.59%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIE 771
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ +L+     + S         ++ T  +      +  +++  +  +       +H+A   GH  + K+++D   N      + + P+H+AC    + +++LLL++  + +   +    PIH A   GHV IV  L+ +  +  + N+ 
Sbjct:  245 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVS 448

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
Match: ANK2 (ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493])

HSP 1 Score: 110.923 bits (276), Expect = 2.300e-25
Identity = 73/291 (25.09%), Postives = 138/291 (47.42%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN--IPTDENFEKL-FDIDSENSESIS------TMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V++ L +    S  +  T+    A+H+A   G  EVVK+L+ +  NI  +      P+++     +I++++ L      LE+ AN    T++ F  L   +   ++++++      T   V+   +HIA  K       L++ ND N     K  + P+H+A  YG+V++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +V+ L+     L     +G +PL +A + ++  CV  +L
Sbjct:   26 NGLNALHLAAKEGHVGLVQELLGRG---SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYL------LENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLL 307

HSP 2 Score: 103.219 bits (256), Expect = 7.185e-23
Identity = 64/268 (23.88%), Postives = 122/268 (45.52%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRP------------IHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEA 948
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ LL+     L     +   +N      + ++          +Q +             +H+A   GH  + KL++D   N          PIHVA   GH++I+ LLL+N  + +  +      +H A + G VE+VR L+ N    +++  E++ P+H A + G  +IV+ L+ +  + +    +G TPL ++     ++ V  +L E  A
Sbjct:  215 DFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL-----LARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALSGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGA 476

HSP 3 Score: 99.3673 bits (246), Expect = 1.726e-21
Identity = 62/246 (25.20%), Postives = 113/246 (45.93%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKR--RPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            A+H+A + G VEVV+ L+     ++        P+HI   +G  EI++LL+                  + +   D+  +   +        P+HI+  +G  ++  ++++         K  + P+HVA  YG +D+ KLLL+     ++  K    P+H A K   ++I   L+  N   E+  + K+   P+H A + GH D+V  L+    N+ +    G T L LA +  +++ V  ILT+
Sbjct:  389 ALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLL------------------QHMAHPDAATTNGYT--------PLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLL--NYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQ-EDKVNVADILTK 605

HSP 4 Score: 98.5969 bits (244), Expect = 2.741e-21
Identity = 57/250 (22.80%), Postives = 107/250 (42.80%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDS--------ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G   V K+L++K+ N     +  + P+H+   +G++ I+ LL+      + + NI  +                    N   +      +  P+HIA   G   IV+L++ +  +      + + P+H++   G VD+  +LLE         K    P+H A K G +++ ++L++     +S       P+H A K   + I   L++      +    G TPL LA +  +   V ++L
Sbjct:  323 ALHVAAHCGHYRVTKLLLDKRANPNARALSGLTPIHVAAFMGHLNIVLLLLQNGASPD-VTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLL 571

HSP 5 Score: 95.5153 bits (236), Expect = 2.703e-20
Identity = 57/262 (21.76%), Postives = 115/262 (43.89%), Query Frame = 1

Query:  142 EVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            E+ + L +   H D         +H++ ++G V+V  +L+               P+H+    G++++ +LL+  R   +S         +I   +N       L +  +E +  I T + V   P+H+A  +GH ++V L++D   N+  + K     +H+A     V++  +L ++    +   K    P+  AC  G+V++V  L++   N  ++      P+H A + GH  I+  L+ +         +G T L +A
Sbjct:  433 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGYTPLHIAAKKNQMQIASTLLNYGAETN--IVTKQGVT--PLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIA 690

HSP 6 Score: 80.4925 bits (197), Expect = 2.047e-15
Identity = 39/146 (26.71%), Postives = 74/146 (50.68%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A   G+ + V   +    ++ T +++    +H+A   GHV +++ LL    + ++  K     +H A   G  E+V++LV+   N  +Q+     P++ A +  H+D+VK+L+ N  N      DG TPL +AL+  +   V ++L
Sbjct:    1 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 146

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 110.153 bits (274), Expect = 5.022e-25
Identity = 64/270 (23.70%), Postives = 129/270 (47.78%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-----------ANIPTDENFEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAF 984
            +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y  +++ I           A+       + L D  ++ NS +++        P+HIAC K H  +++L++    ++    +    P+HVA   GH+ I+K LL+   +    +     P+H A + GH E+ + L++N     ++  + + P+H A + GH ++VK L+ N  N  +    G TPL +A    +   V+ +L  +E    +    ++ F
Sbjct:  276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT-----PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGH---VETVLALLEKEASQACMTKKGF 537

HSP 2 Score: 109.768 bits (273), Expect = 7.174e-25
Identity = 68/255 (26.67%), Postives = 118/255 (46.27%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI--------------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G   V K+L++K        +    P+HI C   ++ ++ LL+     ++++               ++P  +N      +    S ++S +K V+T P+H+A   GH  + K ++ N   +    KD+  P+H A   GH +++KLLLENN            P+H A + GHVE V  L+E   +      +   P+H A K G V + + L+    +      +G TPL +A+ +NN   V ++L
Sbjct:  342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL-----LQRGASPNVSNVK-VET-PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 589

HSP 3 Score: 97.8265 bits (242), Expect = 5.381e-21
Identity = 66/287 (23.00%), Postives = 135/287 (47.04%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L KE +           A+H+A   G  EVV+ L+N   N+  +      P+++     ++E+++ L+    +     N+ T++ F  L     +  E++        T   V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL    +     +    P+H A + G+V +VR+L++     E++  ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:   44 NGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGN-TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN----QNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325

HSP 4 Score: 93.5893 bits (231), Expect = 1.189e-19
Identity = 68/274 (24.82%), Postives = 123/274 (44.89%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKE-----FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            + G+V  V   L+KE          F P      +HVA K G V V ++L+ +  +        + P+H+     N++I++LL+       S A       +I   +N       L     S N+ES+  +      P+H+A  +GH  +V L++    N    +K    P+H+    GHV +  +L+++    +   +    P+H A   G++++V+ L+++  +  ++      P+H A + GH DIV  L+ N  +      DG TPL +A
Sbjct:  512 REGHVETVLALLEKEASQACMTKKGFTP------LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVT-----PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774

HSP 5 Score: 93.2041 bits (230), Expect = 2.004e-19
Identity = 60/251 (23.90%), Postives = 109/251 (43.43%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  ++       I P+HI    GN+ ++RLL+                          +    I T    +  P+H A   GH  I ++++D+   +Q   K+   PIH+A    H+D ++LLL+ +   +        P+H A   GH  + ++L++      S+ +    P+H ACK  HV +++ L+    +++     G TPL +A
Sbjct:  187 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL--------------------------DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411

HSP 6 Score: 92.0485 bits (227), Expect = 4.005e-19
Identity = 58/243 (23.87%), Postives = 108/243 (44.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV K L+  K  +  +   +  P+H    +G+  +++LL+                          EN+ + +   T    P+HIA  +GH   V  +++ + +     K  + P+HVA  YG V + +LLLE +       K    P+H A    +++IV++L+    +  S       P+H A K   V++ + L+    +   E + G TPL LA +  +   V ++L++
Sbjct:  441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--------------------------ENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657

HSP 7 Score: 90.1225 bits (222), Expect = 1.730e-18
Identity = 55/242 (22.73%), Postives = 106/242 (43.80%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL+                              S++        P+HIA  +G+  +V+L++D    ++T  KD   P+H A   GHV I ++LL++    + + K    PIH A +  H++ VR+L++ +   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   ++++L
Sbjct:  176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLL--------------------------NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391

HSP 8 Score: 76.6406 bits (187), Expect = 4.249e-14
Identity = 44/207 (21.26%), Postives = 93/207 (44.93%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +H+A KQ  VEV + L+    +   E +  + P+H+    G+ E++ LL++ + +     N+                             P+H+   +GH  +  ++I +   +    +  + P+HVA  YG++ ++K LL++      + K    P+H A + GH +IV +L++N  +    + +   P+  A + G++ +   L
Sbjct:  606 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN----GNLGNKSGLT----------------------PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786

HSP 9 Score: 73.1738 bits (178), Expect = 4.710e-13
Identity = 57/274 (20.80%), Postives = 114/274 (41.61%), Query Frame = 1

Query:  163 KEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K  L ++ NP     A    +H+A ++G VE V  L+ K+ +          P+H+    G + +  LL+    + ++  N         L      N+  I  +K +  R             P+HIA  +    + + ++    +          P+H+A   GH +++ LLL         +K    P+H   + GHV +  +L+++    ++       P+H A   G++ +VKFL+ ++ ++  +   G +PL  A +  +   V ++L
Sbjct:  487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLL----ERDAHPNAAGKNGLTPLHVAVHHNNLDI--VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754

HSP 10 Score: 72.7886 bits (177), Expect = 5.868e-13
Identity = 40/124 (32.26%), Postives = 64/124 (51.61%), Query Frame = 1

Query:  541 NDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNE 912
            N  ++ T +++    +H+A   GHV ++  LL      ET  K     +H A   G  E+VR LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  V   DG TPL +AL+  +E
Sbjct:   34 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE 157

HSP 11 Score: 58.151 bits (139), Expect = 2.405e-8
Identity = 34/143 (23.78%), Postives = 67/143 (46.85%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH 837
            N +K  D    N   I+T        +H+A  +GH  +V  ++  +  L+T  K     +H+A + G  ++++ L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI+
Sbjct:   24 NLDKALD-HLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165

[Close]

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-----------ANIPTDENFEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAF 984
            +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y  +++ I           A+       + L D  ++ NS +++        P+HIAC K H  +++L++    ++    +    P+HVA   GH+ I+K LL+   +    +     P+H A + GH E+ + L++N     ++  + + P+H A + GH ++VK L+ N  N  +    G TPL +A    +   V+ +L  +E    +    ++ F
Sbjct:  276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT-----PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGH---VETVLALLEKEASQACMTKKGF 537

HSP 2 Score: 109.768 bits (273), Expect = 7.175e-25
Identity = 68/255 (26.67%), Postives = 118/255 (46.27%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI--------------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G   V K+L++K        +    P+HI C   ++ ++ LL+     ++++               ++P  +N      +    S ++S +K V+T P+H+A   GH  + K ++ N   +    KD+  P+H A   GH +++KLLLENN            P+H A + GHVE V  L+E   +      +   P+H A K G V + + L+    +      +G TPL +A+ +NN   V ++L
Sbjct:  342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL-----LQRGASPNVSNVK-VET-PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 589

HSP 3 Score: 97.8265 bits (242), Expect = 5.382e-21
Identity = 66/287 (23.00%), Postives = 135/287 (47.04%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L KE +           A+H+A   G  EVV+ L+N   N+  +      P+++     ++E+++ L+    +     N+ T++ F  L     +  E++        T   V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL    +     +    P+H A + G+V +VR+L++     E++  ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:   44 NGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGN-TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN----QNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325

HSP 4 Score: 93.5893 bits (231), Expect = 1.189e-19
Identity = 68/274 (24.82%), Postives = 123/274 (44.89%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKE-----FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            + G+V  V   L+KE          F P      +HVA K G V V ++L+ +  +        + P+H+     N++I++LL+       S A       +I   +N       L     S N+ES+  +      P+H+A  +GH  +V L++    N    +K    P+H+    GHV +  +L+++    +   +    P+H A   G++++V+ L+++  +  ++      P+H A + GH DIV  L+ N  +      DG TPL +A
Sbjct:  512 REGHVETVLALLEKEASQACMTKKGFTP------LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVT-----PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774

HSP 5 Score: 93.2041 bits (230), Expect = 2.004e-19
Identity = 60/251 (23.90%), Postives = 109/251 (43.43%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  ++       I P+HI    GN+ ++RLL+                          +    I T    +  P+H A   GH  I ++++D+   +Q   K+   PIH+A    H+D ++LLL+ +   +        P+H A   GH  + ++L++      S+ +    P+H ACK  HV +++ L+    +++     G TPL +A
Sbjct:  187 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL--------------------------DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411

HSP 6 Score: 92.0485 bits (227), Expect = 4.005e-19
Identity = 58/243 (23.87%), Postives = 108/243 (44.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV K L+  K  +  +   +  P+H    +G+  +++LL+                          EN+ + +   T    P+HIA  +GH   V  +++ + +     K  + P+HVA  YG V + +LLLE +       K    P+H A    +++IV++L+    +  S       P+H A K   V++ + L+    +   E + G TPL LA +  +   V ++L++
Sbjct:  441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--------------------------ENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657

HSP 7 Score: 90.1225 bits (222), Expect = 1.731e-18
Identity = 55/242 (22.73%), Postives = 106/242 (43.80%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL+                              S++        P+HIA  +G+  +V+L++D    ++T  KD   P+H A   GHV I ++LL++    + + K    PIH A +  H++ VR+L++ +   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   ++++L
Sbjct:  176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLL--------------------------NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391

HSP 8 Score: 76.6406 bits (187), Expect = 4.250e-14
Identity = 44/207 (21.26%), Postives = 93/207 (44.93%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +H+A KQ  VEV + L+    +   E +  + P+H+    G+ E++ LL++ + +     N+                             P+H+   +GH  +  ++I +   +    +  + P+HVA  YG++ ++K LL++      + K    P+H A + GH +IV +L++N  +    + +   P+  A + G++ +   L
Sbjct:  606 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN----GNLGNKSGLT----------------------PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786

HSP 9 Score: 73.1738 bits (178), Expect = 4.711e-13
Identity = 57/274 (20.80%), Postives = 114/274 (41.61%), Query Frame = 1

Query:  163 KEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K  L ++ NP     A    +H+A ++G VE V  L+ K+ +          P+H+    G + +  LL+    + ++  N         L      N+  I  +K +  R             P+HIA  +    + + ++    +          P+H+A   GH +++ LLL         +K    P+H   + GHV +  +L+++    ++       P+H A   G++ +VKFL+ ++ ++  +   G +PL  A +  +   V ++L
Sbjct:  487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLL----ERDAHPNAAGKNGLTPLHVAVHHNNLDI--VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754

HSP 10 Score: 72.7886 bits (177), Expect = 5.869e-13
Identity = 40/124 (32.26%), Postives = 64/124 (51.61%), Query Frame = 1

Query:  541 NDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNE 912
            N  ++ T +++    +H+A   GHV ++  LL      ET  K     +H A   G  E+VR LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  V   DG TPL +AL+  +E
Sbjct:   34 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE 157

HSP 11 Score: 58.151 bits (139), Expect = 2.405e-8
Identity = 34/143 (23.78%), Postives = 67/143 (46.85%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH 837
            N +K  D    N   I+T        +H+A  +GH  +V  ++  +  L+T  K     +H+A + G  ++++ L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI+
Sbjct:   24 NLDKALD-HLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165

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BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
Match: ANK1 (ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492])

HSP 1 Score: 110.153 bits (274), Expect = 5.615e-25
Identity = 64/270 (23.70%), Postives = 129/270 (47.78%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-----------ANIPTDENFEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAF 984
            +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y  +++ I           A+       + L D  ++ NS +++        P+HIAC K H  +++L++    ++    +    P+HVA   GH+ I+K LL+   +    +     P+H A + GH E+ + L++N     ++  + + P+H A + GH ++VK L+ N  N  +    G TPL +A    +   V+ +L  +E    +    ++ F
Sbjct:  309 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT-----PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGH---VETVLALLEKEASQACMTKKGF 570

HSP 2 Score: 109.383 bits (272), Expect = 8.396e-25
Identity = 68/255 (26.67%), Postives = 118/255 (46.27%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI--------------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G   V K+L++K        +    P+HI C   ++ ++ LL+     ++++               ++P  +N      +    S ++S +K V+T P+H+A   GH  + K ++ N   +    KD+  P+H A   GH +++KLLLENN            P+H A + GHVE V  L+E   +      +   P+H A K G V + + L+    +      +G TPL +A+ +NN   V ++L
Sbjct:  375 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL-----LQRGASPNVSNVK-VET-PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 622

HSP 3 Score: 97.8265 bits (242), Expect = 6.063e-21
Identity = 66/287 (23.00%), Postives = 135/287 (47.04%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L KE +           A+H+A   G  EVV+ L+N   N+  +      P+++     ++E+++ L+    +     N+ T++ F  L     +  E++        T   V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL    +     +    P+H A + G+V +VR+L++     E++  ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:   77 NGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGN-TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN----QNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 358

HSP 4 Score: 93.5893 bits (231), Expect = 1.388e-19
Identity = 68/274 (24.82%), Postives = 123/274 (44.89%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKE-----FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            + G+V  V   L+KE          F P      +HVA K G V V ++L+ +  +        + P+H+     N++I++LL+       S A       +I   +N       L     S N+ES+  +      P+H+A  +GH  +V L++    N    +K    P+H+    GHV +  +L+++    +   +    P+H A   G++++V+ L+++  +  ++      P+H A + GH DIV  L+ N  +      DG TPL +A
Sbjct:  545 REGHVETVLALLEKEASQACMTKKGFTP------LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVT-----PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 807

HSP 5 Score: 92.8189 bits (229), Expect = 2.256e-19
Identity = 60/251 (23.90%), Postives = 109/251 (43.43%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  ++       I P+HI    GN+ ++RLL+                          +    I T    +  P+H A   GH  I ++++D+   +Q   K+   PIH+A    H+D ++LLL+ +   +        P+H A   GH  + ++L++      S+ +    P+H ACK  HV +++ L+    +++     G TPL +A
Sbjct:  220 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL--------------------------DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 444

HSP 6 Score: 92.0485 bits (227), Expect = 4.428e-19
Identity = 58/243 (23.87%), Postives = 108/243 (44.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV K L+  K  +  +   +  P+H    +G+  +++LL+                          EN+ + +   T    P+HIA  +GH   V  +++ + +     K  + P+HVA  YG V + +LLLE +       K    P+H A    +++IV++L+    +  S       P+H A K   V++ + L+    +   E + G TPL LA +  +   V ++L++
Sbjct:  474 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--------------------------ENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 690

HSP 7 Score: 90.1225 bits (222), Expect = 1.913e-18
Identity = 55/242 (22.73%), Postives = 106/242 (43.80%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL+                              S++        P+HIA  +G+  +V+L++D    ++T  KD   P+H A   GHV I ++LL++    + + K    PIH A +  H++ VR+L++ +   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   ++++L
Sbjct:  209 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLL--------------------------NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 424

HSP 8 Score: 76.2554 bits (186), Expect = 4.409e-14
Identity = 44/207 (21.26%), Postives = 93/207 (44.93%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +H+A KQ  VEV + L+    +   E +  + P+H+    G+ E++ LL++ + +     N+                             P+H+   +GH  +  ++I +   +    +  + P+HVA  YG++ ++K LL++      + K    P+H A + GH +IV +L++N  +    + +   P+  A + G++ +   L
Sbjct:  639 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN----GNLGNKSGLT----------------------PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 819

HSP 9 Score: 73.1738 bits (178), Expect = 5.017e-13
Identity = 57/274 (20.80%), Postives = 114/274 (41.61%), Query Frame = 1

Query:  163 KEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K  L ++ NP     A    +H+A ++G VE V  L+ K+ +          P+H+    G + +  LL+    + ++  N         L      N+  I  +K +  R             P+HIA  +    + + ++    +          P+H+A   GH +++ LLL         +K    P+H   + GHV +  +L+++    ++       P+H A   G++ +VKFL+ ++ ++  +   G +PL  A +  +   V ++L
Sbjct:  520 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLL----ERDAHPNAAGKNGLTPLHVAVHHNNLDI--VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 787

HSP 10 Score: 72.7886 bits (177), Expect = 6.034e-13
Identity = 40/124 (32.26%), Postives = 64/124 (51.61%), Query Frame = 1

Query:  541 NDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNE 912
            N  ++ T +++    +H+A   GHV ++  LL      ET  K     +H A   G  E+VR LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  V   DG TPL +AL+  +E
Sbjct:   67 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE 190

HSP 11 Score: 58.151 bits (139), Expect = 2.581e-8
Identity = 34/143 (23.78%), Postives = 67/143 (46.85%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH 837
            N +K  D    N   I+T        +H+A  +GH  +V  ++  +  L+T  K     +H+A + G  ++++ L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI+
Sbjct:   57 NLDKALD-HLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 198

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 100.523 bits (249), Expect = 3.123e-22
Identity = 62/248 (25.00%), Postives = 117/248 (47.18%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIA-----NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  ++VV++L+  +  IE      + P+H+   +G I I+  L+      D+E++      ++    N   +  +   N   +         P+HIA   G+ +IV L++    N     +DN+ P+H+A   G  ++  +LL++N       K    P+H A K G++E+VR+L+E     + +   +  P+H A    +  +   L+ N  + +    +G TPL +A + N
Sbjct:  390 LNGFT---PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKN 634

HSP 2 Score: 93.2041 bits (230), Expect = 6.866e-20
Identity = 62/248 (25.00%), Postives = 109/248 (43.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLE-----SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A K+G  EV  IL++   +          P+H+    GN+E++RLL+      D+E     +  ++    N +K+  +  EN  S          P+HIA  K    I   ++    +     +  + P+H++   GH +I  LL+EN      +       +H   +  HV + +IL  N     S+      P+H AC  G +++VKFL+ N  ++  +     TPL  A +  +  CV  +L
Sbjct:  528 LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLL 775

HSP 3 Score: 91.6633 bits (226), Expect = 1.863e-19
Identity = 53/241 (21.99%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   V+  + L+  +  ++   +  + P+H+    G++ + +LL+    D                      NS +++        P+HIAC K    +V+L++     ++   +    P+HVA   G ++I+  LL+     + E      P+H A +    ++VR+L+ N    ++Q  E + P+H A + G+ DIV  L+    N      D  +PL +A +   E    ++L
Sbjct:  330 LHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSAD---------------------PNSRALNGFT-----PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILL 544

HSP 4 Score: 91.6633 bits (226), Expect = 1.914e-19
Identity = 58/241 (24.07%), Postives = 107/241 (44.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G V V K+L+++  +     +    P+HI C    I+++ LL+ YR  +E+                    +ES  T       P+H+A + G  NIV  ++    N          P+H+A      D++++L+ N    + + +    P+H A + G+ +IV +L++   N  +   +   P+H A K G  ++   L+ +  +  +    G TPL LA +  N   V ++L
Sbjct:  363 LHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-------------------TTESGLT-------PLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL 577

HSP 5 Score: 90.8929 bits (224), Expect = 4.033e-19
Identity = 59/244 (24.18%), Postives = 117/244 (47.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    +VV++LI     ++ +      P+HI   +GN +I+ LL+    +    +N  T +N+  L     E  E ++ +       KT+ T+    P+H+A   G+  +V+L+++    +    K+   P+HVA  Y +  +  LLLEN  + +   K    P+H A K   +EI   L++   +  +++     P+H + + GH +I   LI N  ++  +  +G T + L  + ++
Sbjct:  462 LHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN----SNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDH 701

HSP 6 Score: 89.7373 bits (221), Expect = 1.025e-18
Identity = 55/239 (23.01%), Postives = 110/239 (46.03%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A K G +EVV++L+ +   ++ E    + P+H+     N ++  LL+      ++ A       +  L     +N   I++           ++R    P+H++  +GH  I  L+I+N  ++     +    +H+     HV + ++L  N     ++      P+H AC  G + +V+ LVEN  +   +      P+H A + GH + V++L+ N  +   +   G+TPL +A
Sbjct:  561 LHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAK----NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795

HSP 7 Score: 87.4261 bits (215), Expect = 5.615e-18
Identity = 60/274 (21.90%), Postives = 116/274 (42.34%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            ++H+A K+G  EVV+ LI ++  ++         +HI  L G   I+ +L+    ++    N+ +   F  L+    EN E +          + + T     P+ +A  +GH  +V ++++ND                              N     K  + P+H+A  YGH ++ +LLLE       + ++   P+H A K G   +  +L+      +S+  +   P+H A +SGH  +V  L+     +  +  +G  PL +A + ++
Sbjct:   69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANV----NVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDH 338

HSP 8 Score: 86.6557 bits (213), Expect = 9.514e-18
Identity = 57/246 (23.17%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L ++ NP    ++    +H+A   G   V ++L+ K  N+  +   NI P+H+    G   +  LL++                  +   IDS   + ++        P+H A   GH  +V L++     +    K+   P+H+A    HVD  + LL +    +        P+H A   GHV + ++L++ + +  S+ +    P+H ACK   + +V+ L+  +  +E     G TPL +A
Sbjct:  213 LLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLS------------------RGAIIDSRTKDLLT--------PLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVA 432

HSP 9 Score: 82.0333 bits (201), Expect = 2.834e-16
Identity = 60/260 (23.08%), Postives = 109/260 (41.92%), Query Frame = 1

Query:  154 RLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            R+    L +D     +  A+H+A K+       +L+  + N +        P+HI    G+  + +LL      LE  AN+    N++   +I                 P+H+A   G  N+  L++     + +  KD   P+H A   GH  ++ LL+        + K    P+H A +  HV+  R L+ +    +   ++   P+H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  179 RVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLL------LEKGANV----NYQARHNIS----------------PLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL 412

HSP 10 Score: 81.2629 bits (199), Expect = 4.303e-16
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++   EVVK L+    N          P+ +    G+  ++ +L+    D +    +P        D+       + +E++  +++       P+HIA   GH N+ +L+++   N+    + N  P+HVA  +G  ++  LLL      ++  K    P+H A ++GH ++V +LV       ++      P+H A +  HVD  + L++++  ++   +D  TPL +A
Sbjct:  131 NGFT---PLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL--ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFT--PLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVA 366

HSP 11 Score: 81.2629 bits (199), Expect = 5.231e-16
Identity = 53/243 (21.81%), Postives = 106/243 (43.62%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K GN +EV + L +     D     Q   +HVA      +V  +L+    + +        P+HI      +EI   L+ ++ D  + +       ++   E  +++  +  EN   +          +H+   + H  + +++ +N   + +     + P+HVAC +G ++++K L+EN      + +    P+H A + GH   VR L+EN  +   Q    + P+  A + G+V +V+ L
Sbjct:  566 KYGN-LEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 12 Score: 67.781 bits (164), Expect = 9.152e-12
Identity = 34/128 (26.56%), Postives = 67/128 (52.34%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ T++ +    +H+A   GH ++++ L++     +   +     +H A   G   IV ILVEN  N   Q++    P++ A +  H ++VK+L+ +  N  +   DG TPL +AL+  ++  V ++L
Sbjct:   58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL 185

HSP 13 Score: 55.4546 bits (132), Expect = 7.479e-8
Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 1

Query:  631 LLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            LL       T +      +H A K GH E+VR L++     ++   +    +H A  +G   IV  L+ N  N+ V+ ++G TPL +A + N+E  V  +L
Sbjct:   52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLL 152

HSP 14 Score: 54.6842 bits (130), Expect = 1.123e-7
Identity = 30/138 (21.74%), Postives = 64/138 (46.38%), Query Frame = 1

Query:  427 DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN 840
            DI++ N+  ++++        H+A  +GH  +V+ +I     +    +     +H+A + G   I+ +L+EN      +      P++ A +  H E+V+ L+++  N      +   P+  A + GH  +V  L+ N
Sbjct:   58 DINTSNANGLNSL--------HLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187

[Close]

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIA-----NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  ++VV++L+  +  IE      + P+H+   +G I I+  L+      D+E++      ++    N   +  +   N   +         P+HIA   G+ +IV L++    N     +DN+ P+H+A   G  ++  +LL++N       K    P+H A K G++E+VR+L+E     + +   +  P+H A    +  +   L+ N  + +    +G TPL +A + N
Sbjct:  390 LNGFT---PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKN 634

HSP 2 Score: 93.2041 bits (230), Expect = 6.866e-20
Identity = 62/248 (25.00%), Postives = 109/248 (43.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLE-----SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A K+G  EV  IL++   +          P+H+    GN+E++RLL+      D+E     +  ++    N +K+  +  EN  S          P+HIA  K    I   ++    +     +  + P+H++   GH +I  LL+EN      +       +H   +  HV + +IL  N     S+      P+H AC  G +++VKFL+ N  ++  +     TPL  A +  +  CV  +L
Sbjct:  528 LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLL 775

HSP 3 Score: 91.6633 bits (226), Expect = 1.863e-19
Identity = 53/241 (21.99%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   V+  + L+  +  ++   +  + P+H+    G++ + +LL+    D                      NS +++        P+HIAC K    +V+L++     ++   +    P+HVA   G ++I+  LL+     + E      P+H A +    ++VR+L+ N    ++Q  E + P+H A + G+ DIV  L+    N      D  +PL +A +   E    ++L
Sbjct:  330 LHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSAD---------------------PNSRALNGFT-----PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILL 544

HSP 4 Score: 91.6633 bits (226), Expect = 1.914e-19
Identity = 58/241 (24.07%), Postives = 107/241 (44.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G V V K+L+++  +     +    P+HI C    I+++ LL+ YR  +E+                    +ES  T       P+H+A + G  NIV  ++    N          P+H+A      D++++L+ N    + + +    P+H A + G+ +IV +L++   N  +   +   P+H A K G  ++   L+ +  +  +    G TPL LA +  N   V ++L
Sbjct:  363 LHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-------------------TTESGLT-------PLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL 577

HSP 5 Score: 90.8929 bits (224), Expect = 4.033e-19
Identity = 59/244 (24.18%), Postives = 117/244 (47.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    +VV++LI     ++ +      P+HI   +GN +I+ LL+    +    +N  T +N+  L     E  E ++ +       KT+ T+    P+H+A   G+  +V+L+++    +    K+   P+HVA  Y +  +  LLLEN  + +   K    P+H A K   +EI   L++   +  +++     P+H + + GH +I   LI N  ++  +  +G T + L  + ++
Sbjct:  462 LHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN----SNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDH 701

HSP 6 Score: 89.7373 bits (221), Expect = 1.025e-18
Identity = 55/239 (23.01%), Postives = 110/239 (46.03%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A K G +EVV++L+ +   ++ E    + P+H+     N ++  LL+      ++ A       +  L     +N   I++           ++R    P+H++  +GH  I  L+I+N  ++     +    +H+     HV + ++L  N     ++      P+H AC  G + +V+ LVEN  +   +      P+H A + GH + V++L+ N  +   +   G+TPL +A
Sbjct:  561 LHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAK----NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795

HSP 7 Score: 87.4261 bits (215), Expect = 5.615e-18
Identity = 60/274 (21.90%), Postives = 116/274 (42.34%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            ++H+A K+G  EVV+ LI ++  ++         +HI  L G   I+ +L+    ++    N+ +   F  L+    EN E +          + + T     P+ +A  +GH  +V ++++ND                              N     K  + P+H+A  YGH ++ +LLLE       + ++   P+H A K G   +  +L+      +S+  +   P+H A +SGH  +V  L+     +  +  +G  PL +A + ++
Sbjct:   69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANV----NVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDH 338

HSP 8 Score: 86.6557 bits (213), Expect = 9.514e-18
Identity = 57/246 (23.17%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L ++ NP    ++    +H+A   G   V ++L+ K  N+  +   NI P+H+    G   +  LL++                  +   IDS   + ++        P+H A   GH  +V L++     +    K+   P+H+A    HVD  + LL +    +        P+H A   GHV + ++L++ + +  S+ +    P+H ACK   + +V+ L+  +  +E     G TPL +A
Sbjct:  213 LLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLS------------------RGAIIDSRTKDLLT--------PLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVA 432

HSP 9 Score: 82.0333 bits (201), Expect = 2.834e-16
Identity = 60/260 (23.08%), Postives = 109/260 (41.92%), Query Frame = 1

Query:  154 RLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            R+    L +D     +  A+H+A K+       +L+  + N +        P+HI    G+  + +LL      LE  AN+    N++   +I                 P+H+A   G  N+  L++     + +  KD   P+H A   GH  ++ LL+        + K    P+H A +  HV+  R L+ +    +   ++   P+H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  179 RVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLL------LEKGANV----NYQARHNIS----------------PLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL 412

HSP 10 Score: 81.2629 bits (199), Expect = 4.303e-16
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++   EVVK L+    N          P+ +    G+  ++ +L+    D +    +P        D+       + +E++  +++       P+HIA   GH N+ +L+++   N+    + N  P+HVA  +G  ++  LLL      ++  K    P+H A ++GH ++V +LV       ++      P+H A +  HVD  + L++++  ++   +D  TPL +A
Sbjct:  131 NGFT---PLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL--ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFT--PLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVA 366

HSP 11 Score: 81.2629 bits (199), Expect = 5.231e-16
Identity = 53/243 (21.81%), Postives = 106/243 (43.62%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K GN +EV + L +     D     Q   +HVA      +V  +L+    + +        P+HI      +EI   L+ ++ D  + +       ++   E  +++  +  EN   +          +H+   + H  + +++ +N   + +     + P+HVAC +G ++++K L+EN      + +    P+H A + GH   VR L+EN  +   Q    + P+  A + G+V +V+ L
Sbjct:  566 KYGN-LEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 12 Score: 67.781 bits (164), Expect = 9.152e-12
Identity = 34/128 (26.56%), Postives = 67/128 (52.34%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ T++ +    +H+A   GH ++++ L++     +   +     +H A   G   IV ILVEN  N   Q++    P++ A +  H ++VK+L+ +  N  +   DG TPL +AL+  ++  V ++L
Sbjct:   58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL 185

HSP 13 Score: 55.4546 bits (132), Expect = 7.479e-8
Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 1

Query:  631 LLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            LL       T +      +H A K GH E+VR L++     ++   +    +H A  +G   IV  L+ N  N+ V+ ++G TPL +A + N+E  V  +L
Sbjct:   52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLL 152

HSP 14 Score: 54.6842 bits (130), Expect = 1.123e-7
Identity = 30/138 (21.74%), Postives = 64/138 (46.38%), Query Frame = 1

Query:  427 DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN 840
            DI++ N+  ++++        H+A  +GH  +V+ +I     +    +     +H+A + G   I+ +L+EN      +      P++ A +  H E+V+ L+++  N      +   P+  A + GH  +V  L+ N
Sbjct:   58 DINTSNANGLNSL--------HLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 100.523 bits (249), Expect = 3.161e-22
Identity = 62/248 (25.00%), Postives = 117/248 (47.18%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIA-----NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  ++VV++L+  +  IE      + P+H+   +G I I+  L+      D+E++      ++    N   +  +   N   +         P+HIA   G+ +IV L++    N     +DN+ P+H+A   G  ++  +LL++N       K    P+H A K G++E+VR+L+E     + +   +  P+H A    +  +   L+ N  + +    +G TPL +A + N
Sbjct:  390 LNGFT---PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKN 634

HSP 2 Score: 93.2041 bits (230), Expect = 6.885e-20
Identity = 62/248 (25.00%), Postives = 109/248 (43.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLE-----SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A K+G  EV  IL++   +          P+H+    GN+E++RLL+      D+E     +  ++    N +K+  +  EN  S          P+HIA  K    I   ++    +     +  + P+H++   GH +I  LL+EN      +       +H   +  HV + +IL  N     S+      P+H AC  G +++VKFL+ N  ++  +     TPL  A +  +  CV  +L
Sbjct:  528 LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLL 775

HSP 3 Score: 91.6633 bits (226), Expect = 1.868e-19
Identity = 53/241 (21.99%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   V+  + L+  +  ++   +  + P+H+    G++ + +LL+    D                      NS +++        P+HIAC K    +V+L++     ++   +    P+HVA   G ++I+  LL+     + E      P+H A +    ++VR+L+ N    ++Q  E + P+H A + G+ DIV  L+    N      D  +PL +A +   E    ++L
Sbjct:  330 LHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSAD---------------------PNSRALNGFT-----PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILL 544

HSP 4 Score: 91.6633 bits (226), Expect = 1.937e-19
Identity = 58/241 (24.07%), Postives = 107/241 (44.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G V V K+L+++  +     +    P+HI C    I+++ LL+ YR  +E+                    +ES  T       P+H+A + G  NIV  ++    N          P+H+A      D++++L+ N    + + +    P+H A + G+ +IV +L++   N  +   +   P+H A K G  ++   L+ +  +  +    G TPL LA +  N   V ++L
Sbjct:  363 LHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-------------------TTESGLT-------PLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL 577

HSP 5 Score: 90.8929 bits (224), Expect = 4.044e-19
Identity = 59/244 (24.18%), Postives = 117/244 (47.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    +VV++LI     ++ +      P+HI   +GN +I+ LL+    +    +N  T +N+  L     E  E ++ +       KT+ T+    P+H+A   G+  +V+L+++    +    K+   P+HVA  Y +  +  LLLEN  + +   K    P+H A K   +EI   L++   +  +++     P+H + + GH +I   LI N  ++  +  +G T + L  + ++
Sbjct:  462 LHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN----SNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDH 701

HSP 6 Score: 89.7373 bits (221), Expect = 1.028e-18
Identity = 55/239 (23.01%), Postives = 110/239 (46.03%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A K G +EVV++L+ +   ++ E    + P+H+     N ++  LL+      ++ A       +  L     +N   I++           ++R    P+H++  +GH  I  L+I+N  ++     +    +H+     HV + ++L  N     ++      P+H AC  G + +V+ LVEN  +   +      P+H A + GH + V++L+ N  +   +   G+TPL +A
Sbjct:  561 LHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAK----NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795

HSP 7 Score: 87.4261 bits (215), Expect = 5.631e-18
Identity = 60/274 (21.90%), Postives = 116/274 (42.34%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            ++H+A K+G  EVV+ LI ++  ++         +HI  L G   I+ +L+    ++    N+ +   F  L+    EN E +          + + T     P+ +A  +GH  +V ++++ND                              N     K  + P+H+A  YGH ++ +LLLE       + ++   P+H A K G   +  +L+      +S+  +   P+H A +SGH  +V  L+     +  +  +G  PL +A + ++
Sbjct:   69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANV----NVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDH 338

HSP 8 Score: 86.6557 bits (213), Expect = 9.539e-18
Identity = 57/246 (23.17%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L ++ NP    ++    +H+A   G   V ++L+ K  N+  +   NI P+H+    G   +  LL++                  +   IDS   + ++        P+H A   GH  +V L++     +    K+   P+H+A    HVD  + LL +    +        P+H A   GHV + ++L++ + +  S+ +    P+H ACK   + +V+ L+  +  +E     G TPL +A
Sbjct:  213 LLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLS------------------RGAIIDSRTKDLLT--------PLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVA 432

HSP 9 Score: 82.0333 bits (201), Expect = 2.919e-16
Identity = 60/260 (23.08%), Postives = 109/260 (41.92%), Query Frame = 1

Query:  154 RLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            R+    L +D     +  A+H+A K+       +L+  + N +        P+HI    G+  + +LL      LE  AN+    N++   +I                 P+H+A   G  N+  L++     + +  KD   P+H A   GH  ++ LL+        + K    P+H A +  HV+  R L+ +    +   ++   P+H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  179 RVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLL------LEKGANV----NYQARHNIS----------------PLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL 412

HSP 10 Score: 81.2629 bits (199), Expect = 4.353e-16
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++   EVVK L+    N          P+ +    G+  ++ +L+    D +    +P        D+       + +E++  +++       P+HIA   GH N+ +L+++   N+    + N  P+HVA  +G  ++  LLL      ++  K    P+H A ++GH ++V +LV       ++      P+H A +  HVD  + L++++  ++   +D  TPL +A
Sbjct:  131 NGFT---PLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL--ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFT--PLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVA 366

HSP 11 Score: 81.2629 bits (199), Expect = 5.386e-16
Identity = 53/243 (21.81%), Postives = 106/243 (43.62%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K GN +EV + L +     D     Q   +HVA      +V  +L+    + +        P+HI      +EI   L+ ++ D  + +       ++   E  +++  +  EN   +          +H+   + H  + +++ +N   + +     + P+HVAC +G ++++K L+EN      + +    P+H A + GH   VR L+EN  +   Q    + P+  A + G+V +V+ L
Sbjct:  566 KYGN-LEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 12 Score: 67.781 bits (164), Expect = 9.252e-12
Identity = 34/128 (26.56%), Postives = 67/128 (52.34%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ T++ +    +H+A   GH ++++ L++     +   +     +H A   G   IV ILVEN  N   Q++    P++ A +  H ++VK+L+ +  N  +   DG TPL +AL+  ++  V ++L
Sbjct:   58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL 185

HSP 13 Score: 55.4546 bits (132), Expect = 7.557e-8
Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 1

Query:  631 LLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            LL       T +      +H A K GH E+VR L++     ++   +    +H A  +G   IV  L+ N  N+ V+ ++G TPL +A + N+E  V  +L
Sbjct:   52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLL 152

HSP 14 Score: 54.6842 bits (130), Expect = 1.125e-7
Identity = 30/138 (21.74%), Postives = 64/138 (46.38%), Query Frame = 1

Query:  427 DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN 840
            DI++ N+  ++++        H+A  +GH  +V+ +I     +    +     +H+A + G   I+ +L+EN      +      P++ A +  H E+V+ L+++  N      +   P+  A + GH  +V  L+ N
Sbjct:   58 DINTSNANGLNSL--------HLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 100.523 bits (249), Expect = 3.161e-22
Identity = 62/248 (25.00%), Postives = 117/248 (47.18%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIA-----NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  ++VV++L+  +  IE      + P+H+   +G I I+  L+      D+E++      ++    N   +  +   N   +         P+HIA   G+ +IV L++    N     +DN+ P+H+A   G  ++  +LL++N       K    P+H A K G++E+VR+L+E     + +   +  P+H A    +  +   L+ N  + +    +G TPL +A + N
Sbjct:  390 LNGFT---PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKN 634

HSP 2 Score: 93.2041 bits (230), Expect = 6.885e-20
Identity = 62/248 (25.00%), Postives = 109/248 (43.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLE-----SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A K+G  EV  IL++   +          P+H+    GN+E++RLL+      D+E     +  ++    N +K+  +  EN  S          P+HIA  K    I   ++    +     +  + P+H++   GH +I  LL+EN      +       +H   +  HV + +IL  N     S+      P+H AC  G +++VKFL+ N  ++  +     TPL  A +  +  CV  +L
Sbjct:  528 LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLL 775

HSP 3 Score: 91.6633 bits (226), Expect = 1.868e-19
Identity = 53/241 (21.99%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   V+  + L+  +  ++   +  + P+H+    G++ + +LL+    D                      NS +++        P+HIAC K    +V+L++     ++   +    P+HVA   G ++I+  LL+     + E      P+H A +    ++VR+L+ N    ++Q  E + P+H A + G+ DIV  L+    N      D  +PL +A +   E    ++L
Sbjct:  330 LHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSAD---------------------PNSRALNGFT-----PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILL 544

HSP 4 Score: 91.6633 bits (226), Expect = 1.937e-19
Identity = 58/241 (24.07%), Postives = 107/241 (44.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G V V K+L+++  +     +    P+HI C    I+++ LL+ YR  +E+                    +ES  T       P+H+A + G  NIV  ++    N          P+H+A      D++++L+ N    + + +    P+H A + G+ +IV +L++   N  +   +   P+H A K G  ++   L+ +  +  +    G TPL LA +  N   V ++L
Sbjct:  363 LHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-------------------TTESGLT-------PLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL 577

HSP 5 Score: 90.8929 bits (224), Expect = 4.044e-19
Identity = 59/244 (24.18%), Postives = 117/244 (47.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    +VV++LI     ++ +      P+HI   +GN +I+ LL+    +    +N  T +N+  L     E  E ++ +       KT+ T+    P+H+A   G+  +V+L+++    +    K+   P+HVA  Y +  +  LLLEN  + +   K    P+H A K   +EI   L++   +  +++     P+H + + GH +I   LI N  ++  +  +G T + L  + ++
Sbjct:  462 LHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN----SNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDH 701

HSP 6 Score: 89.7373 bits (221), Expect = 1.028e-18
Identity = 55/239 (23.01%), Postives = 110/239 (46.03%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A K G +EVV++L+ +   ++ E    + P+H+     N ++  LL+      ++ A       +  L     +N   I++           ++R    P+H++  +GH  I  L+I+N  ++     +    +H+     HV + ++L  N     ++      P+H AC  G + +V+ LVEN  +   +      P+H A + GH + V++L+ N  +   +   G+TPL +A
Sbjct:  561 LHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAK----NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795

HSP 7 Score: 87.4261 bits (215), Expect = 5.631e-18
Identity = 60/274 (21.90%), Postives = 116/274 (42.34%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            ++H+A K+G  EVV+ LI ++  ++         +HI  L G   I+ +L+    ++    N+ +   F  L+    EN E +          + + T     P+ +A  +GH  +V ++++ND                              N     K  + P+H+A  YGH ++ +LLLE       + ++   P+H A K G   +  +L+      +S+  +   P+H A +SGH  +V  L+     +  +  +G  PL +A + ++
Sbjct:   69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANV----NVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDH 338

HSP 8 Score: 86.6557 bits (213), Expect = 9.539e-18
Identity = 57/246 (23.17%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L ++ NP    ++    +H+A   G   V ++L+ K  N+  +   NI P+H+    G   +  LL++                  +   IDS   + ++        P+H A   GH  +V L++     +    K+   P+H+A    HVD  + LL +    +        P+H A   GHV + ++L++ + +  S+ +    P+H ACK   + +V+ L+  +  +E     G TPL +A
Sbjct:  213 LLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLS------------------RGAIIDSRTKDLLT--------PLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVA 432

HSP 9 Score: 82.0333 bits (201), Expect = 2.919e-16
Identity = 60/260 (23.08%), Postives = 109/260 (41.92%), Query Frame = 1

Query:  154 RLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            R+    L +D     +  A+H+A K+       +L+  + N +        P+HI    G+  + +LL      LE  AN+    N++   +I                 P+H+A   G  N+  L++     + +  KD   P+H A   GH  ++ LL+        + K    P+H A +  HV+  R L+ +    +   ++   P+H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  179 RVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLL------LEKGANV----NYQARHNIS----------------PLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL 412

HSP 10 Score: 81.2629 bits (199), Expect = 4.353e-16
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++   EVVK L+    N          P+ +    G+  ++ +L+    D +    +P        D+       + +E++  +++       P+HIA   GH N+ +L+++   N+    + N  P+HVA  +G  ++  LLL      ++  K    P+H A ++GH ++V +LV       ++      P+H A +  HVD  + L++++  ++   +D  TPL +A
Sbjct:  131 NGFT---PLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL--ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFT--PLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVA 366

HSP 11 Score: 81.2629 bits (199), Expect = 5.386e-16
Identity = 53/243 (21.81%), Postives = 106/243 (43.62%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K GN +EV + L +     D     Q   +HVA      +V  +L+    + +        P+HI      +EI   L+ ++ D  + +       ++   E  +++  +  EN   +          +H+   + H  + +++ +N   + +     + P+HVAC +G ++++K L+EN      + +    P+H A + GH   VR L+EN  +   Q    + P+  A + G+V +V+ L
Sbjct:  566 KYGN-LEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 12 Score: 67.781 bits (164), Expect = 9.252e-12
Identity = 34/128 (26.56%), Postives = 67/128 (52.34%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ T++ +    +H+A   GH ++++ L++     +   +     +H A   G   IV ILVEN  N   Q++    P++ A +  H ++VK+L+ +  N  +   DG TPL +AL+  ++  V ++L
Sbjct:   58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL 185

HSP 13 Score: 55.4546 bits (132), Expect = 7.557e-8
Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 1

Query:  631 LLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            LL       T +      +H A K GH E+VR L++     ++   +    +H A  +G   IV  L+ N  N+ V+ ++G TPL +A + N+E  V  +L
Sbjct:   52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLL 152

HSP 14 Score: 54.6842 bits (130), Expect = 1.125e-7
Identity = 30/138 (21.74%), Postives = 64/138 (46.38%), Query Frame = 1

Query:  427 DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN 840
            DI++ N+  ++++        H+A  +GH  +V+ +I     +    +     +H+A + G   I+ +L+EN      +      P++ A +  H E+V+ L+++  N      +   P+  A + GH  +V  L+ N
Sbjct:   58 DINTSNANGLNSL--------HLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86])

HSP 1 Score: 100.523 bits (249), Expect = 3.170e-22
Identity = 62/248 (25.00%), Postives = 117/248 (47.18%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIA-----NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  ++VV++L+  +  IE      + P+H+   +G I I+  L+      D+E++      ++    N   +  +   N   +         P+HIA   G+ +IV L++    N     +DN+ P+H+A   G  ++  +LL++N       K    P+H A K G++E+VR+L+E     + +   +  P+H A    +  +   L+ N  + +    +G TPL +A + N
Sbjct:  390 LNGFT---PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKN 634

HSP 2 Score: 93.2041 bits (230), Expect = 6.904e-20
Identity = 62/248 (25.00%), Postives = 109/248 (43.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLE-----SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A K+G  EV  IL++   +          P+H+    GN+E++RLL+      D+E     +  ++    N +K+  +  EN  S          P+HIA  K    I   ++    +     +  + P+H++   GH +I  LL+EN      +       +H   +  HV + +IL  N     S+      P+H AC  G +++VKFL+ N  ++  +     TPL  A +  +  CV  +L
Sbjct:  528 LHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLL 775

HSP 3 Score: 91.6633 bits (226), Expect = 1.873e-19
Identity = 53/241 (21.99%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   V+  + L+  +  ++   +  + P+H+    G++ + +LL+    D                      NS +++        P+HIAC K    +V+L++     ++   +    P+HVA   G ++I+  LL+     + E      P+H A +    ++VR+L+ N    ++Q  E + P+H A + G+ DIV  L+    N      D  +PL +A +   E    ++L
Sbjct:  330 LHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSAD---------------------PNSRALNGFT-----PLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILL 544

HSP 4 Score: 91.6633 bits (226), Expect = 1.942e-19
Identity = 58/241 (24.07%), Postives = 107/241 (44.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G V V K+L+++  +     +    P+HI C    I+++ LL+ YR  +E+                    +ES  T       P+H+A + G  NIV  ++    N          P+H+A      D++++L+ N    + + +    P+H A + G+ +IV +L++   N  +   +   P+H A K G  ++   L+ +  +  +    G TPL LA +  N   V ++L
Sbjct:  363 LHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEA-------------------TTESGLT-------PLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLL 577

HSP 5 Score: 90.8929 bits (224), Expect = 4.055e-19
Identity = 59/244 (24.18%), Postives = 117/244 (47.95%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    +VV++LI     ++ +      P+HI   +GN +I+ LL+    +    +N  T +N+  L     E  E ++ +       KT+ T+    P+H+A   G+  +V+L+++    +    K+   P+HVA  Y +  +  LLLEN  + +   K    P+H A K   +EI   L++   +  +++     P+H + + GH +I   LI N  ++  +  +G T + L  + ++
Sbjct:  462 LHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGAN----SNATTRDNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDH 701

HSP 6 Score: 89.7373 bits (221), Expect = 1.031e-18
Identity = 55/239 (23.01%), Postives = 110/239 (46.03%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A K G +EVV++L+ +   ++ E    + P+H+     N ++  LL+      ++ A       +  L     +N   I++           ++R    P+H++  +GH  I  L+I+N  ++     +    +H+     HV + ++L  N     ++      P+H AC  G + +V+ LVEN  +   +      P+H A + GH + V++L+ N  +   +   G+TPL +A
Sbjct:  561 LHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAK----NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIA 795

HSP 7 Score: 87.4261 bits (215), Expect = 5.645e-18
Identity = 60/274 (21.90%), Postives = 116/274 (42.34%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            ++H+A K+G  EVV+ LI ++  ++         +HI  L G   I+ +L+    ++    N+ +   F  L+    EN E +          + + T     P+ +A  +GH  +V ++++ND                              N     K  + P+H+A  YGH ++ +LLLE       + ++   P+H A K G   +  +L+      +S+  +   P+H A +SGH  +V  L+     +  +  +G  PL +A + ++
Sbjct:   69 SLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANV----NVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDH 338

HSP 8 Score: 86.6557 bits (213), Expect = 9.564e-18
Identity = 57/246 (23.17%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L ++ NP    ++    +H+A   G   V ++L+ K  N+  +   NI P+H+    G   +  LL++                  +   IDS   + ++        P+H A   GH  +V L++     +    K+   P+H+A    HVD  + LL +    +        P+H A   GHV + ++L++ + +  S+ +    P+H ACK   + +V+ L+  +  +E     G TPL +A
Sbjct:  213 LLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLS------------------RGAIIDSRTKDLLT--------PLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVA 432

HSP 9 Score: 82.0333 bits (201), Expect = 2.926e-16
Identity = 60/260 (23.08%), Postives = 109/260 (41.92%), Query Frame = 1

Query:  154 RLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            R+    L +D     +  A+H+A K+       +L+  + N +        P+HI    G+  + +LL      LE  AN+    N++   +I                 P+H+A   G  N+  L++     + +  KD   P+H A   GH  ++ LL+        + K    P+H A +  HV+  R L+ +    +   ++   P+H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  179 RVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLL------LEKGANV----NYQARHNIS----------------PLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLL 412

HSP 10 Score: 81.2629 bits (199), Expect = 4.364e-16
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++   EVVK L+    N          P+ +    G+  ++ +L+    D +    +P        D+       + +E++  +++       P+HIA   GH N+ +L+++   N+    + N  P+HVA  +G  ++  LLL      ++  K    P+H A ++GH ++V +LV       ++      P+H A +  HVD  + L++++  ++   +D  TPL +A
Sbjct:  131 NGFT---PLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL--ENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFT--PLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVA 366

HSP 11 Score: 81.2629 bits (199), Expect = 5.400e-16
Identity = 53/243 (21.81%), Postives = 106/243 (43.62%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K GN +EV + L +     D     Q   +HVA      +V  +L+    + +        P+HI      +EI   L+ ++ D  + +       ++   E  +++  +  EN   +          +H+   + H  + +++ +N   + +     + P+HVAC +G ++++K L+EN      + +    P+H A + GH   VR L+EN  +   Q    + P+  A + G+V +V+ L
Sbjct:  566 KYGN-LEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETL 807

HSP 12 Score: 67.781 bits (164), Expect = 9.272e-12
Identity = 34/128 (26.56%), Postives = 67/128 (52.34%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ T++ +    +H+A   GH ++++ L++     +   +     +H A   G   IV ILVEN  N   Q++    P++ A +  H ++VK+L+ +  N  +   DG TPL +AL+  ++  V ++L
Sbjct:   58 DINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLL 185

HSP 13 Score: 55.4546 bits (132), Expect = 7.570e-8
Identity = 30/101 (29.70%), Postives = 49/101 (48.51%), Query Frame = 1

Query:  631 LLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            LL       T +      +H A K GH E+VR L++     ++   +    +H A  +G   IV  L+ N  N+ V+ ++G TPL +A + N+E  V  +L
Sbjct:   52 LLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLL 152

HSP 14 Score: 54.6842 bits (130), Expect = 1.127e-7
Identity = 30/138 (21.74%), Postives = 64/138 (46.38%), Query Frame = 1

Query:  427 DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN 840
            DI++ N+  ++++        H+A  +GH  +V+ +I     +    +     +H+A + G   I+ +L+EN      +      P++ A +  H E+V+ L+++  N      +   P+  A + GH  +V  L+ N
Sbjct:   58 DINTSNANGLNSL--------HLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLEN 187

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Match: Ank2 (gene:FBgn0261788 transcript:FBtr0303119)

HSP 1 Score: 110.153 bits (274), Expect = 2.192e-25
Identity = 57/255 (22.35%), Postives = 120/255 (47.06%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G V V K+L+++  +     +    P+HI C    ++++ LL+ +   + +     T+     L             + +  + S  + T++     P+H+A      +I+++++ N   +    ++   P+H+A   G+VDI+ LLL++    +   K     +H A K G  E+  +L+EN    ++   +   P+H   K GH+ + + L+  + +++ +  +G TPL +A   NN+    ++L
Sbjct:  340 ALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISAT----TESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRG--ETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLL 588

HSP 2 Score: 107.842 bits (268), Expect = 1.365e-24
Identity = 72/317 (22.71%), Postives = 134/317 (42.27%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNP--FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVK-----------------------------LMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            F +  ++GN+  V + LK      D N        A+H+A K G + VV  L+ +   ++         +HI  L G  E+++LL+ +   +    N+ +   F  L+    EN +++  +       +++ T     P+ +A  +GH  +V                              L++DND N     K  + P+H+A  YG+ +I  LL++         K+   P+H A K G   +V +L+E   N E++  +   P+H A +SGH  +V  L+     +  +  +G  PL +A +  +     ++L
Sbjct:   15 FLRAARAGNLERVLEHLKNNI---DINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASV----NVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILL 324

HSP 3 Score: 103.605 bits (257), Expect = 3.381e-23
Identity = 53/240 (22.08%), Postives = 111/240 (46.25%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRC-------DLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +H+A +    ++++IL+     ++        P+HI   +GN++I+ LL+ +         D+ +  +I   E  +++  +  EN  ++         P+H+    GH  + +L++  + ++    K+   P+HVAC Y +  +  LLLE   +     K    P+H A +   ++I   L+E      +++     P+H + + GH +I   LI +K  +     +G TP+ L  + +N
Sbjct:  440 LHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDN 679

HSP 4 Score: 103.219 bits (256), Expect = 4.093e-23
Identity = 64/255 (25.10%), Postives = 111/255 (43.53%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L SD     +  A+H+A K+  V+   +L++   N +        P+HI    GN  I  LLI                  +K  D++     +IS        P+H+A   G  N+V L+++   N++   +D   P+H A   GH  ++ +LLE       + K    P+H A +  HV+  RIL+ +    +   ++    +H A   GHV + K L+    +     ++G TPL +A + N    V+++L
Sbjct:  162 LLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLI------------------QKGADVNYSAKHNIS--------PLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLL 390

HSP 5 Score: 101.293 bits (251), Expect = 1.868e-22
Identity = 53/235 (22.55%), Postives = 109/235 (46.38%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+  K G ++V ++L+ K+ +++ +    + P+H+ C   N ++  LL+       + A       +I   +N   +     E     +        P+H++  +GH  I  L+I++   +    K+   P+H+     +V++ ++L +N    +   K    P+H A   G   +VR L++N  N ++       P+H   + GH  IV  L+ +K N   + ++G+TPL +A
Sbjct:  539 LHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIA 773

HSP 6 Score: 98.2117 bits (243), Expect = 1.819e-21
Identity = 61/250 (24.40%), Postives = 114/250 (45.60%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESI-STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A K+G  EV  +LI     ++        P+H+T   G+I++ +LL+    D+++         ++    N +++  +  E   S  +T K   T P+HIA  K   +I   +++         K  + P+H++   GH +I  LL+E+        K    P+H   +  +V +  IL +N  N +        P+H A   G  ++V+FL+ N  N++     G TPL    +  +   V+++L
Sbjct:  505 ALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHT-PLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLL 753

HSP 7 Score: 97.8265 bits (242), Expect = 2.566e-21
Identity = 65/278 (23.38%), Postives = 124/278 (44.60%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN---IP----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL---TEIEARKKK 960
             L +D NP    ++    +H+A   G   +  +LI K  ++      NI P+H+    G   ++ LL+    ++E+       P         E++ D+  E    IS        P+H+A    H +  ++++ +   +     D    +HVA   GHV + KLLL+ N            P+H ACK   +++V +L+ +  +  +       P+H A   G ++IV +L+ +  + +V  + G+TPL LA   N    + ++L    +++AR ++
Sbjct:  191 LLDNDHNPDVTSKSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARARE 468

HSP 8 Score: 87.0409 bits (214), Expect = 6.819e-18
Identity = 51/241 (21.16%), Postives = 109/241 (45.23%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A + G  +VV +L+ +   I  +    + P+H+     +++  R+L+ +R         P DE       +D   +             +H+A   GH  + KL++D + +      + + P+H+AC    + +++LLL +  +     +    P+H A   G + IV  L++++ + +   +    P+H A ++   DI++ L+ N   ++    + +TPL +A    N   V ++L
Sbjct:  275 LHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRA--------PVDE-----VTVDYLTA-------------LHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLL 489

HSP 9 Score: 71.633 bits (174), Expect = 5.840e-13
Identity = 39/154 (25.32%), Postives = 77/154 (50.00%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKK 957
            A   G+   V   + N+ ++ T++ +    +H+A   GH+ ++  LL      ++  K     +H A   G  E+V++L+E+N +   Q+     P++ A +  H  +V+ L+ N  N  +   DG TPL +A++  ++  V ++L E + R K
Sbjct:   18 AARAGNLERVLEHLKNNIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLL-ESDTRGK 170

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089172)

HSP 1 Score: 108.997 bits (271), Expect = 5.141e-25
Identity = 63/250 (25.20%), Postives = 121/250 (48.40%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLE-------SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             A+H+A K+G   +V++L+               P+H+ C  G   ++++L+     ++       +  ++ T  N   + ++  +N  S +         IHIAC K +  I   ++ +  ++    K  + P+H+A   G+VD+++LLLE    +    K    P+H A + GHV + +IL+E+  N   +      P+H A   GH+D+VKF I N  ++E+    G TPL  A +  + + ++++L
Sbjct:  532 SALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAA-KNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLL 780

HSP 2 Score: 103.99 bits (258), Expect = 2.145e-23
Identity = 64/255 (25.10%), Postives = 123/255 (48.24%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G V+V K+L++ K N     +    P+HI C    I+++ LLI +  ++ +     T+     L             + +  E S  + T++     P+H+A      +I+++++     +    ++   P+HVA   G+++I+ LLL++      +   K   +H A K G   IV++L+EN     +   +   P+H ACK G  ++V+ L+ N  +++ +  +  TPL +A   NN   V+++L
Sbjct:  369 ALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGAT----TESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRG--ETPLHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLL 616

HSP 3 Score: 102.064 bits (253), Expect = 1.122e-22
Identity = 59/235 (25.11%), Postives = 115/235 (48.94%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+ACK G   VV+IL+    +I+ +   ++ P+H+     N  I+ LL+         A       +I   +N+ ++     ++   ++ +      P+H+A   G+ ++V+L+++    +    K+   P+HVA   GHV + ++LLE+        +    P+H A   GH+++V+  +EN+ + E  +     P+H A + GH+ I+  L+ +K N      DG T L +A
Sbjct:  567 LHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIA 800

HSP 4 Score: 100.908 bits (250), Expect = 2.472e-22
Identity = 78/331 (23.56%), Postives = 141/331 (42.60%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLH----SDFNP--FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSE-------------SIST---------------------------MKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++K+N+    F +  +SG++ +V      +FL     SD N        A+H+A K G+V++   L+ +   I+         +HI  L G  +++  LI Y  ++    N+ +   F  L+    EN +             S+ST                              V+   +HIA  K   N  KL++ +D N     K  + P+H+A  YG+VDI  LLL N        K+   P+H ACK G + +  +L+      ++   +   P+H A +SGHV+++K L+     +  +  +G + L +A +  ++    ++L
Sbjct:   32 IIKQNDATISFLRAARSGDIKKVM-----DFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANV----NVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLL 353

HSP 5 Score: 100.523 bits (249), Expect = 3.275e-22
Identity = 49/211 (23.22%), Postives = 100/211 (47.39%), Query Frame = 1

Query:  199 QCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            QC AIH+ACK+ ++E+   L+    ++         P+H+    GN+++++LL+ Y                             IS        P+H+A  +GH  + ++++++  N+    ++ + P+H+A  YGH+D++K  +EN+   E        P+H A + GH+ I+ +L+ +  N  +   +    +H A   G+V +++ L
Sbjct:  630 QC-AIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV---------------------------ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESL 812

HSP 6 Score: 98.5969 bits (244), Expect = 1.658e-21
Identity = 62/250 (24.80%), Postives = 124/250 (49.60%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    ++++IL+ +   ++        P+H+   +GNI I+ LL+ +  ++ + +N       I   E  E +  +  EN    + +      P+H+AC  G  N+V++++ N  ++    K++  P+HVA  Y +  I++LLL+N  +     +     IH ACK  ++EI   L+++  +    +     P+H A + G+VD+V+ L+     +     +G TPL +A +  + + V  IL E
Sbjct:  469 LHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGH-VLVSQILLE 715

HSP 7 Score: 97.8265 bits (242), Expect = 2.447e-21
Identity = 60/232 (25.86%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSEN----------SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             N FT    +H+ACK+  +++V++LI    NI       + P+H+   +G I I+  L+ +    E+ A++PT      L      N          S  +  +      P+H+A   G+ NI+ L++ +   +     D +  +H+A   G  +I+++LLEN        K    P+H ACK G   +V+IL++N  + + Q      P+H A    +  IV+ L+ N  +
Sbjct:  397 LNGFT---PLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQH----EASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSS 621

HSP 8 Score: 96.2857 bits (238), Expect = 8.068e-21
Identity = 63/257 (24.51%), Postives = 111/257 (43.19%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA--NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A K+  V   K+L+    N +        P+HI    GN++I  LL+  + D+  +A  NI                             P+H+AC  G  ++  L++     +    +D   P+H A   GHV+++K LL+ N    T+ K     +H A +  H E   +L++N    +   ++    +H A   GHV + K L+  K N     ++G TPL +A + N    V++++
Sbjct:  191 LLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNI----------------------------TPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLI 419

HSP 9 Score: 95.9005 bits (237), Expect = 1.211e-20
Identity = 65/260 (25.00%), Postives = 117/260 (45.00%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            S F P      +H+A   G V++  +L+N K ++      NI P+H+ C  G + +  LL+        A R  L  +       + E +  +  +N+  ++  K      +H+A    H     L++DN   +     D    +HVA   GHV + KLLL+              P+H ACK   +++V +L+++  N  +       P+H A   G ++IV +L+ ++ + ++  I G+TPL LA   N    + ++L
Sbjct:  233 SGFTP------LHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKN-GLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILL 485

HSP 10 Score: 82.0333 bits (201), Expect = 3.361e-16
Identity = 57/254 (22.44%), Postives = 113/254 (44.49%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCD-----------LESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVACK G + +  +L+ +   I+      + P+H     G++E+++ L+                L   A    DE    L D    N   +  +       +H+A   GH  + KL++D   N      + + P+H+AC    + +++LL+++        +    P+H A   G + IV  L+++  + +   I    P+H A ++   DI++ L+ +   ++    +G+TPL +A    N I + M+L +
Sbjct:  271 LHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLD----NKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGN-INIIMLLLQ 518

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0300497)

HSP 1 Score: 108.997 bits (271), Expect = 5.141e-25
Identity = 63/250 (25.20%), Postives = 121/250 (48.40%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLE-------SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             A+H+A K+G   +V++L+               P+H+ C  G   ++++L+     ++       +  ++ T  N   + ++  +N  S +         IHIAC K +  I   ++ +  ++    K  + P+H+A   G+VD+++LLLE    +    K    P+H A + GHV + +IL+E+  N   +      P+H A   GH+D+VKF I N  ++E+    G TPL  A +  + + ++++L
Sbjct:  532 SALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAA-KNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLL 780

HSP 2 Score: 103.99 bits (258), Expect = 2.145e-23
Identity = 64/255 (25.10%), Postives = 123/255 (48.24%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G V+V K+L++ K N     +    P+HI C    I+++ LLI +  ++ +     T+     L             + +  E S  + T++     P+H+A      +I+++++     +    ++   P+HVA   G+++I+ LLL++      +   K   +H A K G   IV++L+EN     +   +   P+H ACK G  ++V+ L+ N  +++ +  +  TPL +A   NN   V+++L
Sbjct:  369 ALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGAT----TESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRG--ETPLHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLL 616

HSP 3 Score: 102.064 bits (253), Expect = 1.122e-22
Identity = 59/235 (25.11%), Postives = 115/235 (48.94%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+ACK G   VV+IL+    +I+ +   ++ P+H+     N  I+ LL+         A       +I   +N+ ++     ++   ++ +      P+H+A   G+ ++V+L+++    +    K+   P+HVA   GHV + ++LLE+        +    P+H A   GH+++V+  +EN+ + E  +     P+H A + GH+ I+  L+ +K N      DG T L +A
Sbjct:  567 LHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIA 800

HSP 4 Score: 100.908 bits (250), Expect = 2.472e-22
Identity = 78/331 (23.56%), Postives = 141/331 (42.60%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLH----SDFNP--FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSE-------------SIST---------------------------MKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++K+N+    F +  +SG++ +V      +FL     SD N        A+H+A K G+V++   L+ +   I+         +HI  L G  +++  LI Y  ++    N+ +   F  L+    EN +             S+ST                              V+   +HIA  K   N  KL++ +D N     K  + P+H+A  YG+VDI  LLL N        K+   P+H ACK G + +  +L+      ++   +   P+H A +SGHV+++K L+     +  +  +G + L +A +  ++    ++L
Sbjct:   32 IIKQNDATISFLRAARSGDIKKVM-----DFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANV----NVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLL 353

HSP 5 Score: 100.523 bits (249), Expect = 3.275e-22
Identity = 49/211 (23.22%), Postives = 100/211 (47.39%), Query Frame = 1

Query:  199 QCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            QC AIH+ACK+ ++E+   L+    ++         P+H+    GN+++++LL+ Y                             IS        P+H+A  +GH  + ++++++  N+    ++ + P+H+A  YGH+D++K  +EN+   E        P+H A + GH+ I+ +L+ +  N  +   +    +H A   G+V +++ L
Sbjct:  630 QC-AIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV---------------------------ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESL 812

HSP 6 Score: 98.5969 bits (244), Expect = 1.658e-21
Identity = 62/250 (24.80%), Postives = 124/250 (49.60%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    ++++IL+ +   ++        P+H+   +GNI I+ LL+ +  ++ + +N       I   E  E +  +  EN    + +      P+H+AC  G  N+V++++ N  ++    K++  P+HVA  Y +  I++LLL+N  +     +     IH ACK  ++EI   L+++  +    +     P+H A + G+VD+V+ L+     +     +G TPL +A +  + + V  IL E
Sbjct:  469 LHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGH-VLVSQILLE 715

HSP 7 Score: 97.8265 bits (242), Expect = 2.447e-21
Identity = 60/232 (25.86%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSEN----------SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             N FT    +H+ACK+  +++V++LI    NI       + P+H+   +G I I+  L+ +    E+ A++PT      L      N          S  +  +      P+H+A   G+ NI+ L++ +   +     D +  +H+A   G  +I+++LLEN        K    P+H ACK G   +V+IL++N  + + Q      P+H A    +  IV+ L+ N  +
Sbjct:  397 LNGFT---PLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQH----EASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSS 621

HSP 8 Score: 96.2857 bits (238), Expect = 8.068e-21
Identity = 63/257 (24.51%), Postives = 111/257 (43.19%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA--NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A K+  V   K+L+    N +        P+HI    GN++I  LL+  + D+  +A  NI                             P+H+AC  G  ++  L++     +    +D   P+H A   GHV+++K LL+ N    T+ K     +H A +  H E   +L++N    +   ++    +H A   GHV + K L+  K N     ++G TPL +A + N    V++++
Sbjct:  191 LLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNI----------------------------TPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLI 419

HSP 9 Score: 95.9005 bits (237), Expect = 1.211e-20
Identity = 65/260 (25.00%), Postives = 117/260 (45.00%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            S F P      +H+A   G V++  +L+N K ++      NI P+H+ C  G + +  LL+        A R  L  +       + E +  +  +N+  ++  K      +H+A    H     L++DN   +     D    +HVA   GHV + KLLL+              P+H ACK   +++V +L+++  N  +       P+H A   G ++IV +L+ ++ + ++  I G+TPL LA   N    + ++L
Sbjct:  233 SGFTP------LHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKN-GLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILL 485

HSP 10 Score: 82.0333 bits (201), Expect = 3.361e-16
Identity = 57/254 (22.44%), Postives = 113/254 (44.49%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCD-----------LESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVACK G + +  +L+ +   I+      + P+H     G++E+++ L+                L   A    DE    L D    N   +  +       +H+A   GH  + KL++D   N      + + P+H+AC    + +++LL+++        +    P+H A   G + IV  L+++  + +   I    P+H A ++   DI++ L+ +   ++    +G+TPL +A    N I + M+L +
Sbjct:  271 LHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLD----NKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGN-INIIMLLLQ 518

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089171)

HSP 1 Score: 108.997 bits (271), Expect = 5.141e-25
Identity = 63/250 (25.20%), Postives = 121/250 (48.40%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLE-------SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             A+H+A K+G   +V++L+               P+H+ C  G   ++++L+     ++       +  ++ T  N   + ++  +N  S +         IHIAC K +  I   ++ +  ++    K  + P+H+A   G+VD+++LLLE    +    K    P+H A + GHV + +IL+E+  N   +      P+H A   GH+D+VKF I N  ++E+    G TPL  A +  + + ++++L
Sbjct:  532 SALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAA-KNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLL 780

HSP 2 Score: 103.99 bits (258), Expect = 2.145e-23
Identity = 64/255 (25.10%), Postives = 123/255 (48.24%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G V+V K+L++ K N     +    P+HI C    I+++ LLI +  ++ +     T+     L             + +  E S  + T++     P+H+A      +I+++++     +    ++   P+HVA   G+++I+ LLL++      +   K   +H A K G   IV++L+EN     +   +   P+H ACK G  ++V+ L+ N  +++ +  +  TPL +A   NN   V+++L
Sbjct:  369 ALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGAT----TESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRG--ETPLHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLL 616

HSP 3 Score: 102.064 bits (253), Expect = 1.122e-22
Identity = 59/235 (25.11%), Postives = 115/235 (48.94%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+ACK G   VV+IL+    +I+ +   ++ P+H+     N  I+ LL+         A       +I   +N+ ++     ++   ++ +      P+H+A   G+ ++V+L+++    +    K+   P+HVA   GHV + ++LLE+        +    P+H A   GH+++V+  +EN+ + E  +     P+H A + GH+ I+  L+ +K N      DG T L +A
Sbjct:  567 LHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIA 800

HSP 4 Score: 100.908 bits (250), Expect = 2.472e-22
Identity = 78/331 (23.56%), Postives = 141/331 (42.60%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLH----SDFNP--FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSE-------------SIST---------------------------MKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++K+N+    F +  +SG++ +V      +FL     SD N        A+H+A K G+V++   L+ +   I+         +HI  L G  +++  LI Y  ++    N+ +   F  L+    EN +             S+ST                              V+   +HIA  K   N  KL++ +D N     K  + P+H+A  YG+VDI  LLL N        K+   P+H ACK G + +  +L+      ++   +   P+H A +SGHV+++K L+     +  +  +G + L +A +  ++    ++L
Sbjct:   32 IIKQNDATISFLRAARSGDIKKVM-----DFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANV----NVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLL 353

HSP 5 Score: 100.523 bits (249), Expect = 3.275e-22
Identity = 49/211 (23.22%), Postives = 100/211 (47.39%), Query Frame = 1

Query:  199 QCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            QC AIH+ACK+ ++E+   L+    ++         P+H+    GN+++++LL+ Y                             IS        P+H+A  +GH  + ++++++  N+    ++ + P+H+A  YGH+D++K  +EN+   E        P+H A + GH+ I+ +L+ +  N  +   +    +H A   G+V +++ L
Sbjct:  630 QC-AIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV---------------------------ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESL 812

HSP 6 Score: 98.5969 bits (244), Expect = 1.658e-21
Identity = 62/250 (24.80%), Postives = 124/250 (49.60%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    ++++IL+ +   ++        P+H+   +GNI I+ LL+ +  ++ + +N       I   E  E +  +  EN    + +      P+H+AC  G  N+V++++ N  ++    K++  P+HVA  Y +  I++LLL+N  +     +     IH ACK  ++EI   L+++  +    +     P+H A + G+VD+V+ L+     +     +G TPL +A +  + + V  IL E
Sbjct:  469 LHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGH-VLVSQILLE 715

HSP 7 Score: 97.8265 bits (242), Expect = 2.447e-21
Identity = 60/232 (25.86%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSEN----------SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             N FT    +H+ACK+  +++V++LI    NI       + P+H+   +G I I+  L+ +    E+ A++PT      L      N          S  +  +      P+H+A   G+ NI+ L++ +   +     D +  +H+A   G  +I+++LLEN        K    P+H ACK G   +V+IL++N  + + Q      P+H A    +  IV+ L+ N  +
Sbjct:  397 LNGFT---PLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQH----EASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSS 621

HSP 8 Score: 96.2857 bits (238), Expect = 8.068e-21
Identity = 63/257 (24.51%), Postives = 111/257 (43.19%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA--NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A K+  V   K+L+    N +        P+HI    GN++I  LL+  + D+  +A  NI                             P+H+AC  G  ++  L++     +    +D   P+H A   GHV+++K LL+ N    T+ K     +H A +  H E   +L++N    +   ++    +H A   GHV + K L+  K N     ++G TPL +A + N    V++++
Sbjct:  191 LLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNI----------------------------TPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLI 419

HSP 9 Score: 95.9005 bits (237), Expect = 1.211e-20
Identity = 65/260 (25.00%), Postives = 117/260 (45.00%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            S F P      +H+A   G V++  +L+N K ++      NI P+H+ C  G + +  LL+        A R  L  +       + E +  +  +N+  ++  K      +H+A    H     L++DN   +     D    +HVA   GHV + KLLL+              P+H ACK   +++V +L+++  N  +       P+H A   G ++IV +L+ ++ + ++  I G+TPL LA   N    + ++L
Sbjct:  233 SGFTP------LHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKN-GLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILL 485

HSP 10 Score: 82.0333 bits (201), Expect = 3.361e-16
Identity = 57/254 (22.44%), Postives = 113/254 (44.49%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCD-----------LESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVACK G + +  +L+ +   I+      + P+H     G++E+++ L+                L   A    DE    L D    N   +  +       +H+A   GH  + KL++D   N      + + P+H+AC    + +++LL+++        +    P+H A   G + IV  L+++  + +   I    P+H A ++   DI++ L+ +   ++    +G+TPL +A    N I + M+L +
Sbjct:  271 LHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLD----NKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGN-INIIMLLLQ 518

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089173)

HSP 1 Score: 108.997 bits (271), Expect = 5.141e-25
Identity = 63/250 (25.20%), Postives = 121/250 (48.40%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLE-------SIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             A+H+A K+G   +V++L+               P+H+ C  G   ++++L+     ++       +  ++ T  N   + ++  +N  S +         IHIAC K +  I   ++ +  ++    K  + P+H+A   G+VD+++LLLE    +    K    P+H A + GHV + +IL+E+  N   +      P+H A   GH+D+VKF I N  ++E+    G TPL  A +  + + ++++L
Sbjct:  532 SALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAA-KNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLL 780

HSP 2 Score: 103.99 bits (258), Expect = 2.145e-23
Identity = 64/255 (25.10%), Postives = 123/255 (48.24%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+HVA   G V+V K+L++ K N     +    P+HI C    I+++ LLI +  ++ +     T+     L             + +  E S  + T++     P+H+A      +I+++++     +    ++   P+HVA   G+++I+ LLL++      +   K   +H A K G   IV++L+EN     +   +   P+H ACK G  ++V+ L+ N  +++ +  +  TPL +A   NN   V+++L
Sbjct:  369 ALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGAT----TESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRG--ETPLHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLL 616

HSP 3 Score: 102.064 bits (253), Expect = 1.122e-22
Identity = 59/235 (25.11%), Postives = 115/235 (48.94%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+ACK G   VV+IL+    +I+ +   ++ P+H+     N  I+ LL+         A       +I   +N+ ++     ++   ++ +      P+H+A   G+ ++V+L+++    +    K+   P+HVA   GHV + ++LLE+        +    P+H A   GH+++V+  +EN+ + E  +     P+H A + GH+ I+  L+ +K N      DG T L +A
Sbjct:  567 LHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIA 800

HSP 4 Score: 100.908 bits (250), Expect = 2.472e-22
Identity = 78/331 (23.56%), Postives = 141/331 (42.60%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLH----SDFNP--FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSE-------------SIST---------------------------MKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++K+N+    F +  +SG++ +V      +FL     SD N        A+H+A K G+V++   L+ +   I+         +HI  L G  +++  LI Y  ++    N+ +   F  L+    EN +             S+ST                              V+   +HIA  K   N  KL++ +D N     K  + P+H+A  YG+VDI  LLL N        K+   P+H ACK G + +  +L+      ++   +   P+H A +SGHV+++K L+     +  +  +G + L +A +  ++    ++L
Sbjct:   32 IIKQNDATISFLRAARSGDIKKVM-----DFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANV----NVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLL 353

HSP 5 Score: 100.523 bits (249), Expect = 3.275e-22
Identity = 49/211 (23.22%), Postives = 100/211 (47.39%), Query Frame = 1

Query:  199 QCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            QC AIH+ACK+ ++E+   L+    ++         P+H+    GN+++++LL+ Y                             IS        P+H+A  +GH  + ++++++  N+    ++ + P+H+A  YGH+D++K  +EN+   E        P+H A + GH+ I+ +L+ +  N  +   +    +H A   G+V +++ L
Sbjct:  630 QC-AIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV---------------------------ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESL 812

HSP 6 Score: 98.5969 bits (244), Expect = 1.658e-21
Identity = 62/250 (24.80%), Postives = 124/250 (49.60%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    ++++IL+ +   ++        P+H+   +GNI I+ LL+ +  ++ + +N       I   E  E +  +  EN    + +      P+H+AC  G  N+V++++ N  ++    K++  P+HVA  Y +  I++LLL+N  +     +     IH ACK  ++EI   L+++  +    +     P+H A + G+VD+V+ L+     +     +G TPL +A +  + + V  IL E
Sbjct:  469 LHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGH-VLVSQILLE 715

HSP 7 Score: 97.8265 bits (242), Expect = 2.447e-21
Identity = 60/232 (25.86%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSEN----------SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             N FT    +H+ACK+  +++V++LI    NI       + P+H+   +G I I+  L+ +    E+ A++PT      L      N          S  +  +      P+H+A   G+ NI+ L++ +   +     D +  +H+A   G  +I+++LLEN        K    P+H ACK G   +V+IL++N  + + Q      P+H A    +  IV+ L+ N  +
Sbjct:  397 LNGFT---PLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQH----EASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSS 621

HSP 8 Score: 96.2857 bits (238), Expect = 8.068e-21
Identity = 63/257 (24.51%), Postives = 111/257 (43.19%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA--NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A K+  V   K+L+    N +        P+HI    GN++I  LL+  + D+  +A  NI                             P+H+AC  G  ++  L++     +    +D   P+H A   GHV+++K LL+ N    T+ K     +H A +  H E   +L++N    +   ++    +H A   GHV + K L+  K N     ++G TPL +A + N    V++++
Sbjct:  191 LLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNI----------------------------TPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLI 419

HSP 9 Score: 95.9005 bits (237), Expect = 1.211e-20
Identity = 65/260 (25.00%), Postives = 117/260 (45.00%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            S F P      +H+A   G V++  +L+N K ++      NI P+H+ C  G + +  LL+        A R  L  +       + E +  +  +N+  ++  K      +H+A    H     L++DN   +     D    +HVA   GHV + KLLL+              P+H ACK   +++V +L+++  N  +       P+H A   G ++IV +L+ ++ + ++  I G+TPL LA   N    + ++L
Sbjct:  233 SGFTP------LHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKN-GLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILL 485

HSP 10 Score: 82.0333 bits (201), Expect = 3.361e-16
Identity = 57/254 (22.44%), Postives = 113/254 (44.49%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCD-----------LESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVACK G + +  +L+ +   I+      + P+H     G++E+++ L+                L   A    DE    L D    N   +  +       +H+A   GH  + KL++D   N      + + P+H+AC    + +++LL+++        +    P+H A   G + IV  L+++  + +   I    P+H A ++   DI++ L+ +   ++    +G+TPL +A    N I + M+L +
Sbjct:  271 LHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLD----NKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGN-INIIMLLLQ 518

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 123.25 bits (308), Expect = 1.241e-29
Identity = 69/256 (26.95%), Postives = 124/256 (48.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFD-------------IDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   +VK+L++K        +    P+HI C   ++  + LL+ +   LE++    T+     L               +    S + S +K V+T P+H+A   GHC + + ++ N+  +    KD+  P+H A   GH +++KLL+E+    ++       P+H A + GH +  RIL++ N        +   P+H ACK G VD+V+ L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  283 LHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAV----TESGLTPLHVAAFMGHLNIVKSLLQRGASPNASNVK-VET-PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 532

HSP 2 Score: 111.309 bits (277), Expect = 1.066e-25
Identity = 71/267 (26.59%), Postives = 126/267 (47.19%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDS-ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLA-----------LENNNEICVDMILTE 939
            +HVACK G V+VV++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K+   P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   +  S+      P+H A + GH DIV  L+ H     E+   +G +PL +A           L+   E  V MI TE
Sbjct:  481 LHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGIT-----PLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEIT-TNGTSPLGIAKRLGYISVIDVLKLVTEESVSMITTE 741

HSP 3 Score: 109.383 bits (272), Expect = 5.054e-25
Identity = 57/250 (22.80%), Postives = 123/250 (49.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S         +I   E   +   I  + +   + M      P+H+AC  G  ++V+L+++   N     K+   P+HVA  + ++D++KLL+    +  +  +     +H A K   +E+   L++   N  S++++   P+H A + G  D+V  LI  + N+ + + +G TPL L  +  +    DM++ +
Sbjct:  382 LHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQ 631

HSP 4 Score: 104.375 bits (259), Expect = 2.337e-23
Identity = 59/250 (23.60%), Postives = 113/250 (45.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA---NIP----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G + +VK L+ +  +     +    P+H+    G+ E+ + L+     +++ A     P         ++L  +  E+  +  +  T    P+HIA  +GH    ++++D +       K  + P+HVAC YG VD+++LLLE         K    P+H A    ++++V++LV    +  S        +H A K   +++   L+    N   E + G TPL LA +      V +++++
Sbjct:  349 LHVAAFMGHLNIVKSLLQRGASPNASNVKVETPLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISK 598

HSP 5 Score: 101.293 bits (251), Expect = 2.313e-22
Identity = 63/251 (25.10%), Postives = 113/251 (45.02%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  N+       I P+HI    GN+ ++RLL+                  ++   ID++  + ++        P+H A   GH  +V++++D    LQ   K+   PIH+A    H+D ++ LL+ N   +        P+H A   GH  +V++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:  128 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLL------------------DRGAQIDAKTKDELT--------PLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 352

HSP 6 Score: 96.2857 bits (238), Expect = 1.048e-20
Identity = 61/242 (25.21%), Postives = 107/242 (44.21%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL      L   AN+    NF     I                 P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV ++++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  +VK L+          ++G TPL +A + N+   +D++L
Sbjct:  117 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLL------LNRGANV----NFTPKNGIT----------------PLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 332

HSP 7 Score: 94.7449 bits (234), Expect = 3.548e-20
Identity = 60/273 (21.98%), Postives = 118/273 (43.22%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  +    NP +   A    +H+A ++G  +  +IL+++     +       P+H+ C  G ++++ LL+        A +  L  +       N + +  + S+     ST +   T  +HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K    P+H   + GHV I  +LV+   +  + +     P+H AC  G++ +VKFL+  + ++  +   G TPL  A +  +   V ++L
Sbjct:  424 KELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTA-LHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLL 695

HSP 8 Score: 93.9745 bits (232), Expect = 5.421e-20
Identity = 72/280 (25.71%), Postives = 131/280 (46.79%), Query Frame = 1

Query:  109 FEKVVKSGN------VMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY------RCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDI--DGKTPLDLA 894
             E   K GN       +  ++++  E ++   N   Q Q     +++A ++  +EVVK L+    N          P+ +    G+  ++ LLI Y      R     IA    D     +   +  N + +S  KT  T P+HIA    + ++ +L+++   N+    K+   P+H+A   G+V +++LLL+     + + K +  P+H A + GHV +V IL++     +++      PIH A +  H+D V+ L+  + N E++DI  D  TPL +A
Sbjct:   12 LETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLS--KTGFT-PLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLL--QYNAEIDDITLDHLTPLHVA 286

HSP 9 Score: 93.5893 bits (231), Expect = 8.662e-20
Identity = 55/253 (21.74%), Postives = 111/253 (43.87%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V + +V  G       R          N +T   A+H+A KQ  +EV   L+    N   E +  I P+H+    G  +++ LLI+ + ++                ++ ++N  +          P+H+   +GH  I  +++    ++    +  + P+HVAC YG++ ++K LL+      ++ +    P+H A + GH +IV +L+++             P+  A + G++ ++  L
Sbjct:  514 LHVAVHHNNLDVVKLLVSKGGSPHSTAR----------NGYT---ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANV----------------NLGNKNGLT----------PLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVL 727

HSP 10 Score: 77.0258 bits (188), Expect = 1.688e-14
Identity = 62/273 (22.71%), Postives = 121/273 (44.32%), Query Frame = 1

Query:  166 EFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
            E LH+  +  T  +    A+H+A   G  +VV  LIN   N+  +      P+++     ++E+++ L+ +  +     ++PT++ F                       P+ +A  +GH N+V L+I    N  T  K     +H+A          +LL+N+   +   K    P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++ +  D  TPL  A  N +   V+++L +   ++A+ K
Sbjct:    4 ELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGAN----QSLPTEDGFT----------------------PLAVALQQGHENVVALLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKN--GITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTK 244

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 123.25 bits (308), Expect = 1.338e-29
Identity = 69/256 (26.95%), Postives = 124/256 (48.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFD-------------IDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   +VK+L++K        +    P+HI C   ++  + LL+ +   LE++    T+     L               +    S + S +K V+T P+H+A   GHC + + ++ N+  +    KD+  P+H A   GH +++KLL+E+    ++       P+H A + GH +  RIL++ N        +   P+H ACK G VD+V+ L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  375 LHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAV----TESGLTPLHVAAFMGHLNIVKSLLQRGASPNASNVK-VET-PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 624

HSP 2 Score: 109.383 bits (272), Expect = 4.742e-25
Identity = 57/250 (22.80%), Postives = 123/250 (49.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S         +I   E   +   I  + +   + M      P+H+AC  G  ++V+L+++   N     K+   P+HVA  + ++D++KLL+    +  +  +     +H A K   +E+   L++   N  S++++   P+H A + G  D+V  LI  + N+ + + +G TPL L  +  +    DM++ +
Sbjct:  474 LHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQ 723

HSP 3 Score: 104.375 bits (259), Expect = 2.095e-23
Identity = 59/250 (23.60%), Postives = 113/250 (45.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA---NIP----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G + +VK L+ +  +     +    P+H+    G+ E+ + L+     +++ A     P         ++L  +  E+  +  +  T    P+HIA  +GH    ++++D +       K  + P+HVAC YG VD+++LLLE         K    P+H A    ++++V++LV    +  S        +H A K   +++   L+    N   E + G TPL LA +      V +++++
Sbjct:  441 LHVAAFMGHLNIVKSLLQRGASPNASNVKVETPLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISK 690

HSP 4 Score: 101.293 bits (251), Expect = 2.554e-22
Identity = 63/251 (25.10%), Postives = 113/251 (45.02%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  N+       I P+HI    GN+ ++RLL+                  ++   ID++  + ++        P+H A   GH  +V++++D    LQ   K+   PIH+A    H+D ++ LL+ N   +        P+H A   GH  +V++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:  220 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLL------------------DRGAQIDAKTKDELT--------PLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 444

HSP 5 Score: 96.2857 bits (238), Expect = 1.085e-20
Identity = 61/242 (25.21%), Postives = 107/242 (44.21%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL      L   AN+    NF     I                 P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV ++++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  +VK L+          ++G TPL +A + N+   +D++L
Sbjct:  209 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLL------LNRGANV----NFTPKNGIT----------------PLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 424

HSP 6 Score: 94.7449 bits (234), Expect = 3.447e-20
Identity = 71/317 (22.40%), Postives = 139/317 (43.85%), Query Frame = 1

Query:   82 VKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL----------------------------FDIDSENSESISTMKTVQT------------RPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDI--DGKTPLDLA 894
            +   N L       K G+V     ++  E LH+  +  T  +    A+H+A   G  +VV  LIN   N+  +      P+++     ++E+++ L+ +  +     ++PT++ F  L                              I + N ++ +    +Q              P+HIA    + ++ +L+++   N+    K+   P+H+A   G+V +++LLL+     + + K +  P+H A + GHV +V IL++     +++      PIH A +  H+D V+ L+  + N E++DI  D  TPL +A
Sbjct:   73 IANQNGLNGLHLASKEGHV-----KMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGAN----QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLL--QYNAEIDDITLDHLTPLHVA 378

HSP 7 Score: 94.3597 bits (233), Expect = 4.683e-20
Identity = 71/302 (23.51%), Postives = 126/302 (41.72%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDS-ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEK-----------------------------------RRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLA-----------LENNNEICVDMILTE 939
            +HVACK G V+VV++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K+   P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   +  S+                                         P+H A + GH DIV  L+ H     E+   +G +PL +A           L+   E  V MI TE
Sbjct:  573 LHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGIT-----PLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRVSVLLLDASYTGLFSVSVCTLRTFAFSFSLIFLFQLGYTPLHQAAQQGHTDIVTLLLKHGALPNEIT-TNGTSPLGIAKRLGYISVIDVLKLVTEESVSMITTE 868

HSP 8 Score: 86.6557 bits (213), Expect = 1.377e-17
Identity = 53/246 (21.54%), Postives = 106/246 (43.09%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNL 852
            K L K  +    NP +   A    +H+A ++G  +  +IL+++     +       P+H+ C  G ++++ LL+        A +  L  +       N + +  + S+     ST +   T  +HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K    P+H   + GHV I  +LV+   +  + +     P+H AC  G++ +VKFL+  + ++
Sbjct:  516 KELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTA-LHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHV 760

HSP 9 Score: 81.6481 bits (200), Expect = 5.235e-16
Identity = 72/303 (23.76%), Postives = 134/303 (44.22%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSEN-------------SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
            F +  +SGN+ +    +K      D N   Q     +H+A K+G V++V  L++   ++E         +HI  L G  +++  LI Y  ++    N  + + F  L+    EN             ++S+ T       P+ +A  +GH N+V L+I    N  T  K     +H+A          +LL+N+   +   K    P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++ +  D  TPL  A  N +   V+++L +   ++A+ K
Sbjct:   49 FLRAARSGNLEKALDHIKNGI---DINIANQNGLNGLHLASKEGHVKMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANV----NAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFT--PLAVALQQGHENVVALLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKN--GITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTK 336

HSP 10 Score: 61.6178 bits (148), Expect = 1.378e-9
Identity = 36/173 (20.81%), Postives = 83/173 (47.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLES---IANIPTDENFEKLFDIDSENSESISTMKT------------VQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGH---VDILKLLLENNCTTETEDKYK 675
            +H+  ++G V +  +L+ +  ++         P+H+ C  GNI++++ L+  +  + S   ++ +  D ++  LF +      S+ T++T            +   P+H A  +GH +IV L++ +         +   P+ +A   G+   +D+LKL+ E + +  T +K++
Sbjct:  705 LHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRVSVLLLDASYTGLFSV------SVCTLRTFAFSFSLIFLFQLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVLKLVTEESVSMITTEKHR 871

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 121.324 bits (303), Expect = 6.252e-29
Identity = 69/254 (27.17%), Postives = 124/254 (48.82%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEK-LFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   +VK+L++K        +    P+HI C   ++  + LL+ +   LE++          A      N  K L    +  + +I +   V+T P+H+A   GHC + + ++ N+  +    KD+  P+H A   GH +++KLL+E+    ++       P+H A + GH +  RIL++ N        +   P+H ACK G VD+V+ L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  353 LHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKSLLQRGASPNSNIFSSDYVET-PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 605

HSP 2 Score: 102.449 bits (254), Expect = 9.612e-23
Identity = 57/250 (22.80%), Postives = 123/250 (49.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S         +I   E   +   I  + +   + M      P+H+AC  G  ++V+L+++   N     K+   P+HVA  + ++D++KLL+    +  +  +     +H A K   +E+   L++   N  S++++   P+H A + G  D+V  LI  + N+ + + +G TPL L  +  +    DM++ +
Sbjct:  455 LHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQ 704

HSP 3 Score: 100.523 bits (249), Expect = 4.750e-22
Identity = 62/240 (25.83%), Postives = 116/240 (48.33%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVACK G V+VV++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K+   P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   +  S+      P+H A + GH DIV  L+ +         +G +PL +A
Sbjct:  554 LHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGIT-----PLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIA 788

HSP 4 Score: 97.0561 bits (240), Expect = 5.884e-21
Identity = 63/251 (25.10%), Postives = 113/251 (45.02%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  N+       I P+HI    GN+ ++RLL+                  ++   ID++  + ++        P+H A   GH  +V++++D    LQ   K+   PIH+A    H+D ++ LL+ N   +        P+H A   GH  +V++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:  198 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLL------------------DRGAQIDAKTKDELT--------PLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 422

HSP 5 Score: 92.8189 bits (229), Expect = 1.639e-19
Identity = 63/242 (26.03%), Postives = 109/242 (45.04%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL      L   AN+    NF               T K   T P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV ++++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  +VK L+          ++G TPL +A + N+   +D++L
Sbjct:  187 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLL------LNRGANV----NF---------------TPKNGIT-PLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 402

HSP 6 Score: 87.8113 bits (216), Expect = 6.038e-18
Identity = 73/326 (22.39%), Postives = 143/326 (43.87%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL----------------------------FDIDSENSESISTMKTVQT------------RPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDI--DGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH+  +  T  +    A+H+A   G  +VV  LIN   N+  +      P+++     ++E+++ L+ +  +     ++PT++ F  L                              I + N ++ +    +Q              P+HIA    + ++ +L+++   N+    K+   P+H+A   G+V +++LLL+     + + K +  P+H A + GHV +V IL++     +++      PIH A +  H+D V+ L+  + N E++DI  D  TPL +A    +   V ++L
Sbjct:   55 NGLNGLHLASKEGHV-----KMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGAN----QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLL--QYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLL 369

HSP 7 Score: 84.7297 bits (208), Expect = 5.434e-17
Identity = 60/273 (21.98%), Postives = 118/273 (43.22%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  +    NP +   A    +H+A ++G  +  +IL+++     +       P+H+ C  G ++++ LL+        A +  L  +       N + +  + S+     ST +   T  +HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K    P+H   + GHV I  +LV+   +  + +     P+H AC  G++ +VKFL+  + ++  +   G TPL  A +  +   V ++L
Sbjct:  497 KELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYT-ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLL 768

HSP 8 Score: 82.8037 bits (203), Expect = 2.240e-16
Identity = 56/253 (22.13%), Postives = 109/253 (43.08%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V + +V  G       R          N +T   A+H+A KQ  +EV   L+    N   E +  I P+H+    G  +++ LLI+                  K  +++  N   ++        P+H+   +GH  I  +++    ++    +  + P+HVAC YG++ ++K LL+      ++ +    P+H A + GH +IV +L+++             P+  A + G++ ++  L
Sbjct:  587 LHVAVHHNNLDVVKLLVSKGGSPHSTAR----------NGYT---ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLIS------------------KQANVNLGNKNGLT--------PLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVL 800

HSP 9 Score: 72.4034 bits (176), Expect = 5.757e-13
Identity = 68/283 (24.03%), Postives = 129/283 (45.58%), Query Frame = 1

Query:  166 EFLHSD-FNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
            EFL +  F  ++Q     +H+A K+G V++V  L++   ++E         +HI  L G  +++  LI Y  ++    N  + + F  L+    EN   +          +++ T     P+ +A  +GH N+V L+I    N  T  K     +H+A          +LL+N+   +   K    P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++ +  D  TPL  A  N +   V+++L +   ++A+ K
Sbjct:   42 EFLSASCFFLYSQNGLNGLHLASKEGHVKMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANV----NAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFTPLAVALQQGHENVVALLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKN--GITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTK 314

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 121.324 bits (303), Expect = 6.267e-29
Identity = 69/254 (27.17%), Postives = 124/254 (48.82%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEK-LFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   +VK+L++K        +    P+HI C   ++  + LL+ +   LE++          A      N  K L    +  + +I +   V+T P+H+A   GHC + + ++ N+  +    KD+  P+H A   GH +++KLL+E+    ++       P+H A + GH +  RIL++ N        +   P+H ACK G VD+V+ L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  372 LHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKSLLQRGASPNSNIFSSDYVET-PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 624

HSP 2 Score: 102.449 bits (254), Expect = 9.634e-23
Identity = 57/250 (22.80%), Postives = 123/250 (49.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S         +I   E   +   I  + +   + M      P+H+AC  G  ++V+L+++   N     K+   P+HVA  + ++D++KLL+    +  +  +     +H A K   +E+   L++   N  S++++   P+H A + G  D+V  LI  + N+ + + +G TPL L  +  +    DM++ +
Sbjct:  474 LHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQ 723

HSP 3 Score: 100.523 bits (249), Expect = 4.761e-22
Identity = 62/240 (25.83%), Postives = 116/240 (48.33%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVACK G V+VV++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K+   P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   +  S+      P+H A + GH DIV  L+ +         +G +PL +A
Sbjct:  573 LHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGIT-----PLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIA 807

HSP 4 Score: 97.0561 bits (240), Expect = 5.898e-21
Identity = 63/251 (25.10%), Postives = 113/251 (45.02%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  N+       I P+HI    GN+ ++RLL+                  ++   ID++  + ++        P+H A   GH  +V++++D    LQ   K+   PIH+A    H+D ++ LL+ N   +        P+H A   GH  +V++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:  217 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLL------------------DRGAQIDAKTKDELT--------PLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 441

HSP 5 Score: 92.8189 bits (229), Expect = 1.643e-19
Identity = 63/242 (26.03%), Postives = 109/242 (45.04%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL      L   AN+    NF               T K   T P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV ++++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  +VK L+          ++G TPL +A + N+   +D++L
Sbjct:  206 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLL------LNRGANV----NF---------------TPKNGIT-PLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 421

HSP 6 Score: 87.8113 bits (216), Expect = 6.051e-18
Identity = 73/326 (22.39%), Postives = 143/326 (43.87%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL----------------------------FDIDSENSESISTMKTVQT------------RPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDI--DGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH+  +  T  +    A+H+A   G  +VV  LIN   N+  +      P+++     ++E+++ L+ +  +     ++PT++ F  L                              I + N ++ +    +Q              P+HIA    + ++ +L+++   N+    K+   P+H+A   G+V +++LLL+     + + K +  P+H A + GHV +V IL++     +++      PIH A +  H+D V+ L+  + N E++DI  D  TPL +A    +   V ++L
Sbjct:   74 NGLNGLHLASKEGHV-----KMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGAN----QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTKNGLSPIHMAAQGDHMDCVRQLL--QYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLL 388

HSP 7 Score: 84.7297 bits (208), Expect = 5.446e-17
Identity = 60/273 (21.98%), Postives = 118/273 (43.22%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  +    NP +   A    +H+A ++G  +  +IL+++     +       P+H+ C  G ++++ LL+        A +  L  +       N + +  + S+     ST +   T  +HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K    P+H   + GHV I  +LV+   +  + +     P+H AC  G++ +VKFL+  + ++  +   G TPL  A +  +   V ++L
Sbjct:  516 KELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVVELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYT-ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLL 787

HSP 8 Score: 82.8037 bits (203), Expect = 2.244e-16
Identity = 56/253 (22.13%), Postives = 109/253 (43.08%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V + +V  G       R          N +T   A+H+A KQ  +EV   L+    N   E +  I P+H+    G  +++ LLI+                  K  +++  N   ++        P+H+   +GH  I  +++    ++    +  + P+HVAC YG++ ++K LL+      ++ +    P+H A + GH +IV +L+++             P+  A + G++ ++  L
Sbjct:  606 LHVAVHHNNLDVVKLLVSKGGSPHSTAR----------NGYT---ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLIS------------------KQANVNLGNKNGLT--------PLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVL 819

HSP 9 Score: 72.4034 bits (176), Expect = 5.767e-13
Identity = 68/283 (24.03%), Postives = 129/283 (45.58%), Query Frame = 1

Query:  166 EFLHSD-FNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
            EFL +  F  ++Q     +H+A K+G V++V  L++   ++E         +HI  L G  +++  LI Y  ++    N  + + F  L+    EN   +          +++ T     P+ +A  +GH N+V L+I    N  T  K     +H+A          +LL+N+   +   K    P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++ +  D  TPL  A  N +   V+++L +   ++A+ K
Sbjct:   61 EFLSASCFFLYSQNGLNGLHLASKEGHVKMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANV----NAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFTPLAVALQQGHENVVALLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKN--GITPLHIASRRGNVIMVRLLLDRGAQIDAKTKDELTPLHCAARNGHVRVVEILLDQGAPLQAKTK 333

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Match: BX640476.1 (ankyrin 1, erythrocytic b [Source:NCBI gene;Acc:797662])

HSP 1 Score: 119.783 bits (299), Expect = 2.244e-28
Identity = 68/254 (26.77%), Postives = 123/254 (48.43%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEK-LFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   +VK+L++K        +    P+HI C   ++  + LL+ +   LE++          A      N  K L    +  + +I +   V+T P+H+A   GHC + + ++ N+  +    KD+  P+H A   GH +++KLL+E+    ++       P+H A + GH +  RIL++ N        +   P+H ACK G VD+ + L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  325 LHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKSLLQRGASPNSNIFSSDYVET-PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 577

HSP 2 Score: 100.908 bits (250), Expect = 3.383e-22
Identity = 56/250 (22.40%), Postives = 122/250 (48.80%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S         +I   E   +   I  + +   + M      P+H+AC  G  ++ +L+++   N     K+   P+HVA  + ++D++KLL+    +  +  +     +H A K   +E+   L++   N  S++++   P+H A + G  D+V  LI  + N+ + + +G TPL L  +  +    DM++ +
Sbjct:  427 LHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQ 676

HSP 3 Score: 98.9821 bits (245), Expect = 1.667e-21
Identity = 61/240 (25.42%), Postives = 115/240 (47.92%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVACK G V+V ++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K+   P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   +  S+      P+H A + GH DIV  L+ +         +G +PL +A
Sbjct:  526 LHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTALHIAAKQNQLEVASSLLQYGANANSESLQGIT-----PLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIA 760

HSP 4 Score: 83.9593 bits (206), Expect = 1.095e-16
Identity = 60/273 (21.98%), Postives = 117/273 (42.86%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  +    NP +   A    +H+A ++G  +  +IL+++     +       P+H+ C  G +++  LL+        A +  L  +       N + +  + S+     ST +   T  +HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K    P+H   + GHV I  +LV+   +  + +     P+H AC  G++ +VKFL+  + ++  +   G TPL  A +  +   V ++L
Sbjct:  469 KELVKLLMEHKANPDSATTAGHTPLHIAAREGHAQTTRILLDENAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYT-ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLISKQANVNLGNKNGLTPLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLL 740

HSP 5 Score: 82.8037 bits (203), Expect = 2.232e-16
Identity = 56/253 (22.13%), Postives = 109/253 (43.08%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V + +V  G       R          N +T   A+H+A KQ  +EV   L+    N   E +  I P+H+    G  +++ LLI+                  K  +++  N   ++        P+H+   +GH  I  +++    ++    +  + P+HVAC YG++ ++K LL+      ++ +    P+H A + GH +IV +L+++             P+  A + G++ ++  L
Sbjct:  559 LHVAVHHNNLDVVKLLVSKGGSPHSTAR----------NGYT---ALHIAAKQNQLEVASSLLQYGANANSESLQGITPLHLASQEGQPDMVALLIS------------------KQANVNLGNKNGLT--------PLHLVAQEGHVGIADMLVKQGASVYAASRMGYTPLHVACHYGNIKMVKFLLQQQAHVNSKTRLGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVL 772

HSP 6 Score: 73.9442 bits (180), Expect = 1.646e-13
Identity = 69/328 (21.04%), Postives = 130/328 (39.63%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDK-----------------------------DNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKT--------RPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH+  +  T  +    A+H+A   G  +VV  LIN   N+  +      P+++     ++E+++ L+ +  +     ++PT++ F  L     +  E++        T   V+   +HIA          +++ ND N     K                               + P+H+A  Y ++ + +LLL          K  +         PIH A +  H++ VR L++ N   +   ++   P+H A   GH  +VK L+          ++G TPL +A + N+   +D++L
Sbjct:   56 NGLNGLHLASKEGHV-----KMVLELLHNGIDLETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGAN----QSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKVCVLLQDYLSVFLFCTYTESMKCYTLFRQTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKVSSTLILLNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 374

HSP 7 Score: 68.9366 bits (167), Expect = 6.187e-12
Identity = 65/312 (20.83%), Postives = 123/312 (39.42%), Query Frame = 1

Query:  109 FEKVVKSGNV------MEVKKRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY--------------------RCDLESIANIPTDENFEK------------LFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDK--------DNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             E   K GN       +  ++++  E ++   N   Q Q     +++A ++  +EVVK L+    N          P+ +    G+  ++ LLI Y                    R     + N P  +   K            LF   +E+ +  +  +     P+HIA    + ++ +L+++   N+    K        +   PIH+A    H+D ++ LL+ N   +        P+H A   GH  +V++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:   83 LETTTKKGNTALHIAALAGQEKVVAELINYGANVNAQSQKGFSPLYMAAQENHLEVVKYLLEHGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKVCVLLQDYLSVFLFCTYTESMKCYTLFRQTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKVSSTLILLNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 394

HSP 8 Score: 65.0846 bits (157), Expect = 1.219e-10
Identity = 44/188 (23.40%), Postives = 80/188 (42.55%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACK---------------------------------TGHVEIVRILVE-----NNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            PIH+A    H + V+ ++  +  +     D+  P+HVA   GH  ++K+LL+              P+H ACK                                  GH+ IV+ L++     N+  F S  +E   P+H A ++GH ++ +FL+ N   ++ +  D +TPL  A    ++  V +++
Sbjct:  291 PIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMVKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKSLLQRGASPNSNIFSSDYVET--PLHMAARAGHCEVAQFLLQNNAQVDAKAKDDQTPLHCAARMGHKELVKLLM 476

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Match: dapk1 (death associated protein kinase 1 [Source:NCBI gene;Acc:100144678])

HSP 1 Score: 114.39 bits (285), Expect = 1.611e-26
Identity = 83/324 (25.62%), Postives = 149/324 (45.99%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMK-------TVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKV 1032
             N+ + E ++K G  ++V+ +                 AI+ A + G VE +K L    C ++ +       +H+    G+ E+    I Y C + S  +I   E    L          ++           ++ R    PI  A  +G+ +IV+ ++D+  +L   DKD    +H+A     ++++K L+ + C  + +D++   P+H ACK G++ IV  L E  CN +  N   R P+H A  +G V++V++L     N+E   +DGKT  DLA    +E  V ++     AR ++    R  F+   RP P+ + R+K+
Sbjct:  390 GNIQILELLIKRGAQIDVQDK-------------AGSNAIYWASRHGHVETLKFLHQNNCPLDIKDKSGETALHVAARYGHAEV----IQYLCSIGSHPDIQDKEEETPLHCAAWHGYYPVAKALCQAGCNVNIRNREGETPILTAAARGYHDIVECLVDHGGDLDATDKDGHIALHLAVRRCQMEVVKTLIIHGCFVDFQDRHGNTPLHVACKDGNLPIVMALCEARCNLDITNKYGRTPLHLAANNGIVEVVRYLCVAGANVEALTLDGKTAEDLARSEQHESVVSLL-----ARLRR-DTYRTLFIQQLRPSPTPQPRIKL 690

HSP 2 Score: 83.1889 bits (204), Expect = 2.563e-16
Identity = 42/136 (30.88%), Postives = 72/136 (52.94%), Query Frame = 1

Query:  478 TRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPL 885
            T P+ IA   G+  I++L+I     +   DK     I+ A  +GHV+ LK L +NNC  + +DK     +H A + GH E+++ L     + + Q+ E+  P+H A   G+  + K L    CN+ + + +G+TP+
Sbjct:  380 TPPLLIAAGCGNIQILELLIKRGAQIDVQDKAGSNAIYWASRHGHVETLKFLHQNNCPLDIKDKSGETALHVAARYGHAEVIQYLCSIGSHPDIQDKEEETPLHCAAWHGYYPVAKALCQAGCNVNIRNREGETPI 515

HSP 3 Score: 66.6254 bits (161), Expect = 5.181e-11
Identity = 29/107 (27.10%), Postives = 62/107 (57.94%), Query Frame = 1

Query:  565 DKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPL 885
            +K    P+ +A   G++ IL+LL++     + +DK  +  I++A + GHVE ++ L +NNC  + ++      +H A + GH +++++L     + +++D + +TPL
Sbjct:  376 NKHGTPPLLIAAGCGNIQILELLIKRGAQIDVQDKAGSNAIYWASRHGHVETLKFLHQNNCPLDIKDKSGETALHVAARYGHAEVIQYLCSIGSHPDIQDKEEETPL 482

HSP 4 Score: 55.0694 bits (131), Expect = 1.993e-7
Identity = 25/85 (29.41%), Postives = 48/85 (56.47%), Query Frame = 1

Query:  640 NNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +N      +K+ T P+  A   G+++I+ +L++     + Q+      I++A + GHV+ +KFL  N C L+++D  G+T L +A
Sbjct:  368 SNYDVNQPNKHGTPPLLIAAGCGNIQILELLIKRGAQIDVQDKAGSNAIYWASRHGHVETLKFLHQNNCPLDIKDKSGETALHVA 452

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Match: pan3 (poly(A) specific ribonuclease subunit PAN3 [Source:Xenbase;Acc:XB-GENE-5731378])

HSP 1 Score: 113.62 bits (283), Expect = 1.966e-26
Identity = 68/265 (25.66%), Postives = 128/265 (48.30%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESIS----------TMKTVQTR-PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVE--NNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKI 963
            A+H+A + G   + K+LI K  NI      +  P+H+       E+  +LIA   ++    N+ T E F  L       +  ++            K  Q+R P+H+A   G   +V+L+++N  +  + +KD   P+H+A   GH++I+ ++L+       +D     P+HYA  TG  EI + L++   N N + +N+ ++ P+H A + GH D++  L+ N   +   D +  TPL  A +  +   V  +++ ++  K  +
Sbjct:  267 ALHLAVQGGDASITKLLIRKGININIAGPGDQTPLHVAAFHNKQELADILIAAGANV----NVVTKELFTPLHIASQRGNLHVAQSLLHHKANVNAKDKQSRTPLHLAAEGGAYELVQLLLNNKADPNSTEKDKKTPLHIAAAAGHIEIVNVMLKGRARCAVKDMDGCTPMHYAAATGSSEIAKALLKAGKNKNVDEKNVWRKTPLHLAAEHGHSDLINLLLQNGAAINALDNNRDTPLHCACKAGHLSSVQTLVSWVQGEKANL 527

HSP 2 Score: 98.2117 bits (243), Expect = 2.334e-21
Identity = 63/234 (26.92%), Postives = 111/234 (47.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDK--YKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH----NKCNLEVEDIDGKTPLDLA 894
            +H+A ++G + V + L++ K N+  +   +  P+H+    G  E+++LL+  + D       P                   ST K  +T P+HIA   GH  IV +M+         D D   P+H A   G  +I K LL+       ++K  ++  P+H A + GH +++ +L++N     + +  +  P+H ACK+GH+  V+ L+      K NL+  +   KTPL +A
Sbjct:  334 LHIASQRGNLHVAQSLLHHKANVNAKDKQSRTPLHLAAEGGAYELVQLLLNNKAD-------PN------------------STEKDKKT-PLHIAAAAGHIEIVNVMLKGRARCAVKDMDGCTPMHYAAATGSSEIAKALLKAGKNKNVDEKNVWRKTPLHLAAEHGHSDLINLLLQNGAAINALDNNRDTPLHCACKAGHLSSVQTLVSWVQGEKANLQATNGLKKTPLQVA 541

HSP 3 Score: 72.7886 bits (177), Expect = 3.395e-13
Identity = 68/299 (22.74%), Postives = 134/299 (44.82%), Query Frame = 1

Query:   91 NNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQ-------------NIEKRRPIHY-----ACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++++ VF+ V K G++  ++  L+   +++  NP  +   +H+A   G V V++ LINK   I+ + I +  P+H     G+ E +++L+     + S+             D DS               P+H+A    H N+VK+++  +   Q  ++ N+  IH+A   G+  +++LLL+N    +  D+     + YA   GH++ V++L+E   + +S              NI     I Y     A + G  +  + LI     L+V   +  T L LA++  +     +++
Sbjct:   18 SSSMTVFDAVTK-GDLSILRNILRDTDINA-VNPSGET-LLHIAAASGHVAVIEYLINKGAKIDCKDIKHRTPLHRAAENGHGEAVKVLLRAGAFIYSL-------------DDDS-------------LTPLHLAAENNHQNVVKILLQEEGR-QYKNRHNF--IHMAATQGNNKLMQLLLKNKAPVDAVDEKSQTALLYAVSGGHLKTVKMLLEAGASIDSSIIDAAFATNNERTNINATNDIQYTPLLLAAELGKTESAQALIEKGAQLDVRTPNMSTALHLAVQGGDASITKLLI 284

HSP 4 Score: 71.633 bits (174), Expect = 9.831e-13
Identity = 54/241 (22.41%), Postives = 106/241 (43.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            IH+A  QG  +++++L+  K  ++     +   +      G+++ +++L      LE+ A+I +    +  F  ++E + +I+    +Q  P+ +A   G     + +I+    L     +    +H+A   G   I KLL+               P+H A      E+  IL+    N      E   P+H A + G++ + + L+H+K N+  +D   +TPL LA E      V ++L
Sbjct:  151 IHMAATQGNNKLMQLLLKNKAPVDAVDEKSQTALLYAVSGGHLKTVKML------LEAGASIDSSI-IDAAFATNNERT-NINATNDIQYTPLLLAAELGKTESAQALIEKGAQLDVRTPNMSTALHLAVQGGDASITKLLIRKGININIAGPGDQTPLHVAAFHNKQELADILIAAGANVNVVTKELFTPLHIASQRGNLHVAQSLLHHKANVNAKDKQSRTPLHLAAEGGAYELVQLLL 383

HSP 5 Score: 64.6994 bits (156), Expect = 1.560e-10
Identity = 49/179 (27.37%), Postives = 86/179 (48.04%), Query Frame = 1

Query:  595 ACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVD-APRPGPSTKERMKVTVKARIETKPERNICKICYDREVDCVLSCGHV 1128
            A   G + IL+ +L +          +T  +H A  +GHV ++  L+      + ++I+ R P+H A ++GH + VK L+     +   D D  TPL LA ENN++  V ++L E E R+ K    R  F+  A   G +   ++ +  KA ++   E++   + Y       +S GH+
Sbjct:   26 AVTKGDLSILRNILRDTDINAVNPSGETL-LHIAAASGHVAVIEYLINKGAKIDCKDIKHRTPLHRAAENGHGEAVKVLLRAGAFIYSLDDDSLTPLHLAAENNHQNVVKILLQE-EGRQYK---NRHNFIHMAATQGNNKLMQLLLKNKAPVDAVDEKSQTALLY------AVSGGHL 193

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Match: senp1 (SUMO specific peptidase 1 [Source:Xenbase;Acc:XB-GENE-1014921])

HSP 1 Score: 106.686 bits (265), Expect = 3.975e-24
Identity = 67/261 (25.67%), Postives = 120/261 (45.98%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN---NCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAF 984
            +H+A  +    +V++L+ KK N+  +   +   +H +   G+  I R+L+                          E S S++ +      P+H+AC  G  NIV++ +  + +L    +DNW  +H A   GH++I++LL +    N   +T D     P+H A + GH  + RILV+  C+    +I  + P+H A ++GH    +FL+    ++     +G T LDLA    +   V +++ E    K K S    +F
Sbjct:  476 LHIAADKKLKNIVELLLGKKINVNAKDEDHFTALHFSAQNGDECITRMLL--------------------------EKSASLNEVDIKGRTPLHVACQHGQENIVRVFLRREADLTFKGQDNWLALHYAAWQGHLNIVRLLAKQPGANINAQTSDGRT--PLHLAAQRGHYRVARILVDLRCDVNIPSILMKTPLHVAAETGHTSTARFLLSRGASVNAVTSEGFTALDLASNLGHYSAVKLLMDEQSNVKLKDSTEEDSF 708

HSP 2 Score: 85.5001 bits (210), Expect = 3.076e-17
Identity = 51/220 (23.18%), Postives = 91/220 (41.36%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDN-DCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVED 864
            A+H + + G   + ++L+ K  ++ +  I    P+H+ C  G   I+R+ +    DL         +N+  L                      H A W+GH NIV+L+      N+     D   P+H+A   GH  + ++L++  C           P+H A +TGH    R L+    +  +   E    +  A   GH   VK L+  + N++++D
Sbjct:  508 ALHFSAQNGDECITRMLLEKSASLNEVDIKGRTPLHVACQHGQENIVRVFLRREADL----TFKGQDNWLAL----------------------HYAAWQGHLNIVRLLAKQPGANINAQTSDGRTPLHLAAQRGHYRVARILVDLRCDVNIPSILMKTPLHVAAETGHTSTARFLLSRGASVNAVTSEGFTALDLASNLGHYSAVKLLMDEQSNVKLKD 701

HSP 3 Score: 82.0333 bits (201), Expect = 5.014e-16
Identity = 46/155 (29.68%), Postives = 78/155 (50.32%), Query Frame = 1

Query:  478 TRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHN-KCNLEVEDIDGKTPLDLALENNN----EICVDM 927
            + P+HIA  K   NIV+L++    N+   D+D++  +H +   G   I ++LLE + +    D     P+H AC+ G   IVR+ +    +   +  +    +HYA   GH++IV+ L      N+  +  DG+TPL LA +  +     I VD+
Sbjct:  473 STPLHIAADKKLKNIVELLLGKKINVNAKDEDHFTALHFSAQNGDECITRMLLEKSASLNEVDIKGRTPLHVACQHGQENIVRVFLRREADLTFKGQDNWLALHYAAWQGHLNIVRLLAKQPGANINAQTSDGRTPLHLAAQRGHYRVARILVDL 627

HSP 4 Score: 55.8398 bits (133), Expect = 1.008e-7
Identity = 32/136 (23.53%), Postives = 64/136 (47.06%), Query Frame = 1

Query:  487 IHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +H+A   G     KL++  + +    +     P+H+A      +I++LLL        +D+     +H++ + G   I R+L+E + +    +I+ R P+H AC+ G  +IV+  +  + +L  +  D    L  A
Sbjct:  443 LHLAVENGQEECAKLLLLYNASPNMTNLKGSTPLHIAADKKLKNIVELLLGKKINVNAKDEDHFTALHFSAQNGDECITRMLLEKSASLNEVDIKGRTPLHVACQHGQENIVRVFLRREADLTFKGQDNWLALHYA 578

HSP 5 Score: 49.6766 bits (117), Expect = 8.296e-6
Identity = 33/140 (23.57%), Postives = 66/140 (47.14%), Query Frame = 1

Query:  514 CNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
              ++K++   D +L    + +   +H+A   G  +  KLLL  N +    +   + P+H A       IV +L+    N  +++ +    +H++ ++G   I + L+    +L   DI G+TPL +A ++  E  V + L
Sbjct:  421 AKLMKILQPQDVDLVLEGRSSL--LHLAVENGQEECAKLLLLYNASPNMTNLKGSTPLHIAADKKLKNIVELLLGKKINVNAKDEDHFTALHFSAQNGDECITRMLLEKSASLNEVDIKGRTPLHVACQHGQENIVRVFL 558

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 103.605 bits (257), Expect = 7.461e-23
Identity = 63/280 (22.50%), Postives = 126/280 (45.00%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N +       + GNV+ V+  L +     D     +   +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y+  ++ I              +D                P+H+A   GH  + KL++D          + + P+H+AC   H+ +++LLL++  + +   +    P+H A   GH+ IV+ L++   +    +++   P+H A ++ H D+  FLI NK  +     D +TPL  A  + +   V ++L
Sbjct:  271 NGISALHIASRRGNVIMVRLLLDRG-AQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDIT-------------LD-------------HLTPLHVAAHCGHHRVAKLLLDKGAKSNARALNGFTPLHIACKKSHIRVMELLLKSGASIDAVTESGLTPLHVASFMGHLPIVKTLLQKGASPNVFSVKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLL 523

HSP 2 Score: 99.3673 bits (246), Expect = 1.755e-21
Identity = 58/235 (24.68%), Postives = 120/235 (51.06%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-NIPTDENFE-KLFDIDSENS----ESISTMKTVQ-TRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G +++ ++L+ ++ +        + P+H+     ++ I+RLL+         A N  T  +   K   +D+  +     +    +++Q   P+H+A  +GH ++V L++    N+   +K +  P+H+A   GH++I ++L+ ++ +   E +    P+H AC  G++++V+ L+++  N  +       P+H A + GH DIV  L+ N        ++G TPL +A
Sbjct:  573 LHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIA 807

HSP 3 Score: 95.9005 bits (237), Expect = 1.859e-20
Identity = 59/252 (23.41%), Postives = 116/252 (46.03%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
             N FT    +H+ACK+  + V+++L+    +I+      + P+H+   +G++ I++ L+                            S ++ ++K V+T P+H+A    H ++   +I N   +    KD+  P+H A   GH ++++LLLEN    +        P+H   + GH +   +L++N     S   +   P+H A K G + I + L+  + +       G TPL +A+ +N+   V ++L +
Sbjct:  402 LNGFT---PLHIACKKSHIRVMELLLKSGASIDAVTESGLTPLHVASFMGHLPIVKTLL------------------------QKGASPNVFSVK-VET-PLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNK 624

HSP 4 Score: 89.3521 bits (220), Expect = 3.076e-18
Identity = 59/243 (24.28%), Postives = 97/243 (39.92%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    +V   LI  K  +      +  P+H     G+ E++RLL+                          EN        T    P+H+    GH    +L++DN     +  K  + P+HVA  YG + I +LLLE      +  K    P+H A    H+ IVR+L+    +          P+H A K   VD  + L+        + + G TPL LA +  +   V ++L++
Sbjct:  474 LHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLL--------------------------ENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSK 690

HSP 5 Score: 87.8113 bits (216), Expect = 8.089e-18
Identity = 64/291 (21.99%), Postives = 134/291 (46.05%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESIST------MK-TVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH D    T  +    A+H+A   G  +VV+ L+N   N+  +      P+++     ++ +++ L+    +     N+ T++ F  L     +  E++        MK  V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL          +     +H A + G+V +VR+L++     ++   ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:   77 NGLNALHLSSKEGHV-----KMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGAN----QNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLSKTGFTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLL 358

HSP 6 Score: 87.0409 bits (214), Expect = 1.473e-17
Identity = 57/252 (22.62%), Postives = 110/252 (43.65%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-----------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A + G  E+V++L+    + +        P+H+T   G+ +   LL+    D ++     T + F  L            ++  E     ++       P+H+A +  H NIV+L+++   +     ++ + P+H+A     VD  + LL+   T   +      P+H A + GH ++V +L+    N    N     P+H A + GH++I + L+ +  ++  E   G  PL +A    N   V  +L
Sbjct:  507 LHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLL----DNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLL 754

HSP 7 Score: 84.7297 bits (208), Expect = 1.003e-16
Identity = 52/243 (21.40%), Postives = 111/243 (45.68%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY--RCDLESIANI-----PTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K G +   +  L++E  H +    T    +HVA     + +V++L+NK  +          P+H+     +++  R L+ +   C+ +S+  +        E    +  +      ++         P+H+A  +GH NI ++++ +D ++    +  + P+HVAC YG++ ++K LL++        K    P+H A + GH +IV +L++N       ++    P+  A + G++ +   L
Sbjct:  578 KYGKIQIAELLLERE-AHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLGYISVTDVL 819

HSP 8 Score: 82.0333 bits (201), Expect = 6.057e-16
Identity = 66/279 (23.66%), Postives = 129/279 (46.24%), Query Frame = 1

Query:  106 VFEKVVKSGNV------MEVKKRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY------RCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            V E   K GN       +  ++ + +E ++   N  +Q Q     +++A ++  + VVK L+    N          P+ +    G+  ++  LI+Y      R     IA    D     +   +  N++ +S  KT  T P+HIA    + N+ +L+++   N+    ++    +H+A   G+V +++LLL+     +   K +  P+H A + GHV I  IL+++    +++      PIH A +  H+D V+ L+  + +++   +D  TPL +A
Sbjct:  103 VLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLS--KTGFT-PLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVA 378

HSP 9 Score: 73.1738 bits (178), Expect = 4.432e-13
Identity = 39/132 (29.55%), Postives = 69/132 (52.27%), Query Frame = 1

Query:  541 NDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            N  ++ T +++    +H++   GHV ++  LL  +   ET  K     +H A   G  ++VR LV +  N  SQ+ +   P++ A +  H+ +VKFL+ N  N  +   DG TPL +AL+  +E  V  +++
Sbjct:   67 NGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLIS 198

HSP 10 Score: 62.7734 bits (151), Expect = 8.641e-10
Identity = 34/142 (23.94%), Postives = 68/142 (47.89%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI 834
            N +K  D    N   I+T        +H++  +GH  +V  ++  D  L+T  K     +H+A + G  D+++ L+ +     ++ +    P++ A +  H+ +V+ L+EN  N      +   P+  A + GH ++V +LI
Sbjct:   57 NLDKALD-HLRNGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLI 197

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080])

HSP 1 Score: 103.219 bits (256), Expect = 7.561e-23
Identity = 63/280 (22.50%), Postives = 126/280 (45.00%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N +       + GNV+ V+  L +     D     +   +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y+  ++ I              +D                P+H+A   GH  + KL++D          + + P+H+AC   H+ +++LLL++  + +   +    P+H A   GH+ IV+ L++   +    +++   P+H A ++ H D+  FLI NK  +     D +TPL  A  + +   V ++L
Sbjct:  196 NGISALHIASRRGNVIMVRLLLDRG-AQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDIT-------------LD-------------HLTPLHVAAHCGHHRVAKLLLDKGAKSNARALNGFTPLHIACKKSHIRVMELLLKSGASIDAVTESGLTPLHVASFMGHLPIVKTLLQKGASPNVFSVKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLL 448

HSP 2 Score: 99.3673 bits (246), Expect = 1.763e-21
Identity = 58/235 (24.68%), Postives = 120/235 (51.06%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-NIPTDENFE-KLFDIDSENS----ESISTMKTVQ-TRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G +++ ++L+ ++ +        + P+H+     ++ I+RLL+         A N  T  +   K   +D+  +     +    +++Q   P+H+A  +GH ++V L++    N+   +K +  P+H+A   GH++I ++L+ ++ +   E +    P+H AC  G++++V+ L+++  N  +       P+H A + GH DIV  L+ N        ++G TPL +A
Sbjct:  498 LHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIA 732

HSP 3 Score: 95.9005 bits (237), Expect = 1.867e-20
Identity = 59/252 (23.41%), Postives = 116/252 (46.03%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
             N FT    +H+ACK+  + V+++L+    +I+      + P+H+   +G++ I++ L+                            S ++ ++K V+T P+H+A    H ++   +I N   +    KD+  P+H A   GH ++++LLLEN    +        P+H   + GH +   +L++N     S   +   P+H A K G + I + L+  + +       G TPL +A+ +N+   V ++L +
Sbjct:  327 LNGFT---PLHIACKKSHIRVMELLLKSGASIDAVTESGLTPLHVASFMGHLPIVKTLL------------------------QKGASPNVFSVK-VET-PLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNK 549

HSP 4 Score: 89.3521 bits (220), Expect = 3.061e-18
Identity = 59/243 (24.28%), Postives = 97/243 (39.92%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A +    +V   LI  K  +      +  P+H     G+ E++RLL+                          EN        T    P+H+    GH    +L++DN     +  K  + P+HVA  YG + I +LLLE      +  K    P+H A    H+ IVR+L+    +          P+H A K   VD  + L+        + + G TPL LA +  +   V ++L++
Sbjct:  399 LHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLL--------------------------ENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSK 615

HSP 5 Score: 87.8113 bits (216), Expect = 8.052e-18
Identity = 64/291 (21.99%), Postives = 134/291 (46.05%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESIST------MK-TVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH D    T  +    A+H+A   G  +VV+ L+N   N+  +      P+++     ++ +++ L+    +     N+ T++ F  L     +  E++        MK  V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL          +     +H A + G+V +VR+L++     ++   ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:    2 NGLNALHLSSKEGHV-----KMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGAN----QNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLSKTGFTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLL 283

HSP 6 Score: 87.0409 bits (214), Expect = 1.479e-17
Identity = 57/252 (22.62%), Postives = 110/252 (43.65%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-----------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A + G  E+V++L+    + +        P+H+T   G+ +   LL+    D ++     T + F  L            ++  E     ++       P+H+A +  H NIV+L+++   +     ++ + P+H+A     VD  + LL+   T   +      P+H A + GH ++V +L+    N    N     P+H A + GH++I + L+ +  ++  E   G  PL +A    N   V  +L
Sbjct:  432 LHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLL----DNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLL 679

HSP 7 Score: 84.3445 bits (207), Expect = 1.017e-16
Identity = 52/243 (21.40%), Postives = 111/243 (45.68%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY--RCDLESIANI-----PTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            K G +   +  L++E  H +    T    +HVA     + +V++L+NK  +          P+H+     +++  R L+ +   C+ +S+  +        E    +  +      ++         P+H+A  +GH NI ++++ +D ++    +  + P+HVAC YG++ ++K LL++        K    P+H A + GH +IV +L++N       ++    P+  A + G++ +   L
Sbjct:  503 KYGKIQIAELLLERE-AHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLGYISVTDVL 744

HSP 8 Score: 82.0333 bits (201), Expect = 6.030e-16
Identity = 66/279 (23.66%), Postives = 129/279 (46.24%), Query Frame = 1

Query:  106 VFEKVVKSGNV------MEVKKRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY------RCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            V E   K GN       +  ++ + +E ++   N  +Q Q     +++A ++  + VVK L+    N          P+ +    G+  ++  LI+Y      R     IA    D     +   +  N++ +S  KT  T P+HIA    + N+ +L+++   N+    ++    +H+A   G+V +++LLL+     +   K +  P+H A + GHV I  IL+++    +++      PIH A +  H+D V+ L+  + +++   +D  TPL +A
Sbjct:   28 VLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLS--KTGFT-PLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVA 303

HSP 9 Score: 69.3218 bits (168), Expect = 6.888e-12
Identity = 37/117 (31.62%), Postives = 62/117 (52.99%), Query Frame = 1

Query:  586 IHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +H++   GHV ++  LL  +   ET  K     +H A   G  ++VR LV +  N  SQ+ +   P++ A +  H+ +VKFL+ N  N  +   DG TPL +AL+  +E  V  +++
Sbjct:    7 LHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLIS 123

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 112.079 bits (279), Expect = 2.410e-26
Identity = 74/291 (25.43%), Postives = 139/291 (47.77%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN--IPTDENFEKL-FDIDSENSESIS------TMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V++ L +    S  +  T+    A+H+A   G  EVVK+L+ +  NI  +      P+++     +I++++ L      LE+ AN    T++ F  L   +   ++++++      T   V+   +HIA  K       L++ ND N     K  + P+H+A  YG+V++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +V+ L+  K  L     +G +PL +A + ++  CV  +L
Sbjct:   75 NGLNALHLAAKEGHVGLVQELLGRG---SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYL------LENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLL 356

HSP 2 Score: 96.6709 bits (239), Expect = 3.396e-21
Identity = 64/267 (23.97%), Postives = 113/267 (42.32%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
             L +D     +  A+H+A ++   +   +L+    N + +      P+HI    GN+ +  LL+                N     D  + N             P+H+A  +G+ N+VKL++D    +    +D   P+H A   GH  +++LLLE         K    P+H A +  HVE V+ L++     +   ++    +H A   GH  + K L+  + N     ++G TPL +A +  N I V  +L +  A  + I+E
Sbjct:  194 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNG----------ITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITE 433

HSP 3 Score: 85.5001 bits (210), Expect = 1.689e-17
Identity = 53/246 (21.54%), Postives = 109/246 (44.31%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L +D N   Q ++    +H+A   G V V  +L+N+   ++      I P+H+    GN  +++LL+                  ++   ID++  + ++        P+H A   GH  +V+L+++    L    K+   P+H+A    HV+ +K LL+     +         +H A   GH  + ++L++   N  ++ +    P+H ACK   + +++ L+    +++     G TP+ +A
Sbjct:  223 LLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLL------------------DRGGQIDAKTRDGLT--------PLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVA 442

HSP 4 Score: 79.7221 bits (195), Expect = 1.282e-15
Identity = 39/146 (26.71%), Postives = 74/146 (50.68%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A   G+ + V   +    ++ T +++    +H+A   GHV +++ LL    + ++  K     +H A   G  E+V++LV+   N  +Q+     P++ A +  H+D+VK+L+ N  N      DG TPL +AL+  +   V ++L
Sbjct:   50 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILL 195

HSP 5 Score: 72.7886 bits (177), Expect = 2.220e-13
Identity = 45/208 (21.63%), Postives = 93/208 (44.71%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRP------------IHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNI 768
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ LL+  +  L     +   +N      + ++          +Q +             +H+A   GH  + KL++D   N      + + P+H+AC    + +++LL++   + +   +    PIH A   GH+ IV +L++N  + +  NI
Sbjct:  264 DFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPL-----LARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNI 466

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 107.457 bits (267), Expect = 6.719e-25
Identity = 75/333 (22.52%), Postives = 147/333 (44.14%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCN----------------------LQTND---------------KDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ME  +K+++   F +  ++GN+ +V + LK      D N   Q    A+H+A K+G V +V+ L+ +  +++         +HI  L G  E++++L+    ++ + +        +   EN   +     EN  + ST       P+ +A  +GH   V ++++ND                        L  ND               +  + P+H+A  YG+V++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +V+ L+  K  L     +G +PL +A + ++  CV  +L
Sbjct:   38 MERKRKSDSNASFLRAARAGNLDKVVEYLKGGI---DINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLL 367

HSP 2 Score: 85.5001 bits (210), Expect = 1.446e-17
Identity = 69/313 (22.04%), Postives = 130/313 (41.53%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLL-------------------------------IAYRCDLESIANIPT--------DENFEKLFDIDSENSESISTMKTVQTR-----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N L       K G+V  V++ L +    S  +  T+    A+H+A   G  EVVK+L+ +  NI  +      P+++     +I++++ L                               I    D +    +P         D     L   +  N++  S M   +T      P+HIA   G+ N+  L+++    +    ++   P+HVA   G+ +++KLLL+     + + +    P+H A ++GH ++V +L+E      ++      P+H A +  HV+ VK L+  K  ++   +D  T L +A
Sbjct:   78 NGLNALHLAAKEGHVGLVQELLGRG---SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVA 387

HSP 3 Score: 83.9593 bits (206), Expect = 4.434e-17
Identity = 53/235 (22.55%), Postives = 99/235 (42.13%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILI--NKKCNIEQEMIWN------IKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             L +D     +  A+H+A ++   +   +L+  +   +++ +M+ N        P+HI    GN+ +  LL+                N     D  + N  +          P+H+A  +G+ N+VKL++D    +    +D   P+H A   GH  +++LLLE         K    P+H A +  HVE V+ L++     +   ++    +H A   GH  + K L+  + N
Sbjct:  197 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNGIT----------PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN 405

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 104.76 bits (260), Expect = 3.625e-24
Identity = 73/331 (22.05%), Postives = 147/331 (44.41%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCN----------------------LQTND---------------KDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +++K+++   F +  ++GN+ +V + LK      D N   Q    A+H+A K+G V +V+ L+ +  +++         +HI  L G  E++++L+    ++ + +        +   EN   +     EN  + ST       P+ +A  +GH   V ++++ND                        L  ND               +  + P+H+A  YG+V++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +V+ L+  K  L     +G +PL +A + ++  CV  +L
Sbjct:    4 MLQKSDSNASFLRAARAGNLDKVVEYLKGGI---DINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLL 331

HSP 2 Score: 85.1149 bits (209), Expect = 1.760e-17
Identity = 69/313 (22.04%), Postives = 130/313 (41.53%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLL-------------------------------IAYRCDLESIANIPT--------DENFEKLFDIDSENSESISTMKTVQTR-----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N L       K G+V  V++ L +    S  +  T+    A+H+A   G  EVVK+L+ +  NI  +      P+++     +I++++ L                               I    D +    +P         D     L   +  N++  S M   +T      P+HIA   G+ N+  L+++    +    ++   P+HVA   G+ +++KLLL+     + + +    P+H A ++GH ++V +L+E      ++      P+H A +  HV+ VK L+  K  ++   +D  T L +A
Sbjct:   42 NGLNALHLAAKEGHVGLVQELLGRG---SSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVA 351

HSP 3 Score: 82.8037 bits (203), Expect = 9.500e-17
Identity = 53/235 (22.55%), Postives = 99/235 (42.13%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILI--NKKCNIEQEMIWN------IKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN 849
             L +D     +  A+H+A ++   +   +L+  +   +++ +M+ N        P+HI    GN+ +  LL+                N     D  + N  +          P+H+A  +G+ N+VKL++D    +    +D   P+H A   GH  +++LLLE         K    P+H A +  HVE V+ L++     +   ++    +H A   GH  + K L+  + N
Sbjct:  161 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNGIT----------PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN 369

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 106.686 bits (265), Expect = 4.371e-24
Identity = 59/229 (25.76%), Postives = 106/229 (46.29%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            A+HVA   G   V K+L++K+ N     +    P+HI C    I+++ LL+ Y   +++I                   +ES  T       PIH+A + GH NIV L++ N  +    +      +H+A   G V++++ LL N    +   + +  P+H A + G  EIV++L+++  + ++       P+H + + G VD+   L+       +    G TPL +A
Sbjct:  364 ALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAI-------------------TESGLT-------PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA 566

HSP 2 Score: 102.449 bits (254), Expect = 1.129e-22
Identity = 64/299 (21.40%), Postives = 138/299 (46.15%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEA 948
            + V  K  N  + + ++  G  ++ K R           P      +H A + G  +VV++L+ +K  +       + P+H+     ++E ++ L+ Y+  ++ +        ++       ++  +  +   + +        P+HIAC K    +++L++    ++Q   +    PIHVA   GH++I+ LLL+N  + +  +      +H A + G VE+VR L+ N    +++  E++ P+H A + G  +IV+ L+ +  + +    +G TPL ++     ++ V  +L E  A
Sbjct:  266 LHVASKRGNTNMVKLLLDRGGQIDAKTR-------DGLTP------LHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGA 550

HSP 3 Score: 98.5969 bits (244), Expect = 1.898e-21
Identity = 67/266 (25.19%), Postives = 124/266 (46.62%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDI--DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKR--RPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEM 972
            A+H+A + G VEVV+ L+     ++        P+HI   +G  EI++LL+ +    ++         +I   E    +  +  ++  + S++T K     P+H+A   G  ++ KL++       +  K+   P+HVA  Y +  +  LLLE   +     K    P+H A K   ++I   L+  N   E+  + K+   P+H A + GH D+V  L+    N+ +    G T L LA +  +++ V  ILT+  A +   +++
Sbjct:  463 ALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT--PLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLL--NYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQ-EDKVNVADILTKHGADRDAYTKL 723

HSP 4 Score: 94.7449 bits (234), Expect = 3.245e-20
Identity = 71/305 (23.28%), Postives = 147/305 (48.20%), Query Frame = 1

Query:   82 VKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKR------RPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL---TEIEARKK 957
            ++++++   F +  ++GN+ +V + LK      D N   Q    A+H+A K+G V +V+ L+ +  +++         +HI  L G  E++++L+      +  ANI          +  S+N  +          P+++A  + H ++VK +++N  N  T  +D + P+ VA   GH   + +LLEN    +T+ K +   +H A +    +   +L++N  N + +S+ +  R       P+H A   G+V++   L++    ++    +G TPL +A +  N   V ++L    +I+A+ +
Sbjct:   22 IRQSDSNASFLRAARAGNLDKVVEYLKGGI---DINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANI----------NAQSQNGFT----------PLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTR 293

HSP 5 Score: 94.7449 bits (234), Expect = 3.682e-20
Identity = 65/275 (23.64%), Postives = 119/275 (43.27%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILI--NKKCNIEQEMIWN------IKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
             L +D     +  A+H+A ++   +   +L+  +   +++ +M+ N        P+HI    GN+ +  LL+                N     D  + N  +          P+H+A  +G+ N+VKL++D    +    +D   P+H A   GH  +++LLLE         K    P+H A +  HVE V+ L++     +   ++    +H A   GH  + K L+  + N     ++G TPL +A +  N I V  +L +  A  + I+E
Sbjct:  178 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNGIT----------PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITE 425

HSP 6 Score: 92.4337 bits (228), Expect = 1.704e-19
Identity = 57/271 (21.03%), Postives = 113/271 (41.70%), Query Frame = 1

Query:  142 EVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            E+ + L +   H D         +H++ ++G V+V  +L+               P+H+    G++++ +LL+  R   +S         ++    + +K+  +  E   S          P+HIA  K    I   +++      T  K    P+H+A   GH D++ LLL+         K     +H A +   V +  IL ++  + ++       P+  AC  G+V +V FL+    N+  +  +G TPL  A +  +   ++++L
Sbjct:  507 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 777

HSP 7 Score: 90.8929 bits (224), Expect = 5.436e-19
Identity = 51/235 (21.70%), Postives = 104/235 (44.26%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G ++V K+L+ ++   +      + P+H+     N ++  LL+       + A       +I   +N  ++           +T+      P+H+A  +GH ++V L++D   N+  + K     +H+A     V++  +L ++    +   K    P+  AC  G+V++V  L++   N  ++      P+H A + GH  I+  L+ +         +G T L +A
Sbjct:  563 LHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIA 797

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Match: Ank2 (ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025])

HSP 1 Score: 106.301 bits (264), Expect = 4.844e-24
Identity = 59/229 (25.76%), Postives = 106/229 (46.29%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            A+HVA   G   V K+L++K+ N     +    P+HI C    I+++ LL+ Y   +++I                   +ES  T       PIH+A + GH NIV L++ N  +    +      +H+A   G V++++ LL N    +   + +  P+H A + G  EIV++L+++  + ++       P+H + + G VD+   L+       +    G TPL +A
Sbjct:  347 ALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAI-------------------TESGLT-------PIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVA 549

HSP 2 Score: 102.064 bits (253), Expect = 1.383e-22
Identity = 64/299 (21.40%), Postives = 138/299 (46.15%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEA 948
            + V  K  N  + + ++  G  ++ K R           P      +H A + G  +VV++L+ +K  +       + P+H+     ++E ++ L+ Y+  ++ +        ++       ++  +  +   + +        P+HIAC K    +++L++    ++Q   +    PIHVA   GH++I+ LLL+N  + +  +      +H A + G VE+VR L+ N    +++  E++ P+H A + G  +IV+ L+ +  + +    +G TPL ++     ++ V  +L E  A
Sbjct:  249 LHVASKRGNTNMVKLLLDRGGQIDAKTR-------DGLTP------LHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHIS-AREGQVDVASVLLEAGA 533

HSP 3 Score: 98.5969 bits (244), Expect = 1.724e-21
Identity = 67/266 (25.19%), Postives = 124/266 (46.62%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDI--DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKR--RPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEM 972
            A+H+A + G VEVV+ L+     ++        P+HI   +G  EI++LL+ +    ++         +I   E    +  +  ++  + S++T K     P+H+A   G  ++ KL++       +  K+   P+HVA  Y +  +  LLLE   +     K    P+H A K   ++I   L+  N   E+  + K+   P+H A + GH D+V  L+    N+ +    G T L LA +  +++ V  ILT+  A +   +++
Sbjct:  446 ALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFT--PLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLL--NYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQ-EDKVNVADILTKHGADRDAYTKL 706

HSP 4 Score: 95.5153 bits (236), Expect = 1.701e-20
Identity = 72/306 (23.53%), Postives = 148/306 (48.37%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKR------RPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL---TEIEARKK 957
            +++K+++   F +  ++GN+ +V + LK      D N   Q    A+H+A K+G V +V+ L+ +  +++         +HI  L G  E++++L+      +  ANI          +  S+N  +          P+++A  + H ++VK +++N  N  T  +D + P+ VA   GH   + +LLEN    +T+ K +   +H A +    +   +L++N  N + +S+ +  R       P+H A   G+V++   L++    ++    +G TPL +A +  N   V ++L    +I+A+ +
Sbjct:    4 MLQKSDSNASFLRAARAGNLDKVVEYLKGGI---DINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLV------KEGANI----------NAQSQNGFT----------PLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTR 276

HSP 5 Score: 94.7449 bits (234), Expect = 3.798e-20
Identity = 65/275 (23.64%), Postives = 119/275 (43.27%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILI--NKKCNIEQEMIWN------IKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
             L +D     +  A+H+A ++   +   +L+  +   +++ +M+ N        P+HI    GN+ +  LL+                N     D  + N  +          P+H+A  +G+ N+VKL++D    +    +D   P+H A   GH  +++LLLE         K    P+H A +  HVE V+ L++     +   ++    +H A   GH  + K L+  + N     ++G TPL +A +  N I V  +L +  A  + I+E
Sbjct:  161 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNGIT----------PLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITE 408

HSP 6 Score: 92.4337 bits (228), Expect = 1.666e-19
Identity = 57/271 (21.03%), Postives = 113/271 (41.70%), Query Frame = 1

Query:  142 EVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            E+ + L +   H D         +H++ ++G V+V  +L+               P+H+    G++++ +LL+  R   +S         ++    + +K+  +  E   S          P+HIA  K    I   +++      T  K    P+H+A   GH D++ LLL+         K     +H A +   V +  IL ++  + ++       P+  AC  G+V +V FL+    N+  +  +G TPL  A +  +   ++++L
Sbjct:  490 EIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLL 760

HSP 7 Score: 91.2781 bits (225), Expect = 4.773e-19
Identity = 51/235 (21.70%), Postives = 104/235 (44.26%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G ++V K+L+ ++   +      + P+H+     N ++  LL+       + A       +I   +N  ++           +T+      P+H+A  +GH ++V L++D   N+  + K     +H+A     V++  +L ++    +   K    P+  AC  G+V++V  L++   N  ++      P+H A + GH  I+  L+ +         +G T L +A
Sbjct:  546 LHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIA 780

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Match: sp|P16157|ANK1_HUMAN (Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=3)

HSP 1 Score: 110.153 bits (274), Expect = 2.412e-24
Identity = 64/270 (23.70%), Postives = 129/270 (47.78%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-----------ANIPTDENFEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAF 984
            +H A + G V + +IL++    I+ +    + P+H+     +++ +RLL+ Y  +++ I           A+       + L D  ++ NS +++        P+HIAC K H  +++L++    ++    +    P+HVA   GH+ I+K LL+   +    +     P+H A + GH E+ + L++N     ++  + + P+H A + GH ++VK L+ N  N  +    G TPL +A    +   V+ +L  +E    +    ++ F
Sbjct:  276 LHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFT-----PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGH---VETVLALLEKEASQACMTKKGF 537

HSP 2 Score: 109.768 bits (273), Expect = 3.446e-24
Identity = 68/255 (26.67%), Postives = 118/255 (46.27%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI--------------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA   G   V K+L++K        +    P+HI C   ++ ++ LL+     ++++               ++P  +N      +    S ++S +K V+T P+H+A   GH  + K ++ N   +    KD+  P+H A   GH +++KLLLENN            P+H A + GHVE V  L+E   +      +   P+H A K G V + + L+    +      +G TPL +A+ +NN   V ++L
Sbjct:  342 LHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNL-----LQRGASPNVSNVK-VET-PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLL 589

HSP 3 Score: 97.8265 bits (242), Expect = 2.584e-20
Identity = 66/287 (23.00%), Postives = 135/287 (47.04%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L KE +           A+H+A   G  EVV+ L+N   N+  +      P+++     ++E+++ L+    +     N+ T++ F  L     +  E++        T   V+   +HIA          +++ ND N     K  + P+H+A  Y ++++ +LLL    +     +    P+H A + G+V +VR+L++     E++  ++  P+H A ++GHV I + L+ +   ++ +  +G +P+ +A + ++  CV ++L
Sbjct:   44 NGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGN-TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN----QNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLL 325

HSP 4 Score: 93.5893 bits (231), Expect = 5.710e-19
Identity = 68/274 (24.82%), Postives = 123/274 (44.89%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKE-----FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            + G+V  V   L+KE          F P      +HVA K G V V ++L+ +  +        + P+H+     N++I++LL+       S A       +I   +N       L     S N+ES+  +      P+H+A  +GH  +V L++    N    +K    P+H+    GHV +  +L+++    +   +    P+H A   G++++V+ L+++  +  ++      P+H A + GH DIV  L+ N  +      DG TPL +A
Sbjct:  512 REGHVETVLALLEKEASQACMTKKGFTP------LHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVT-----PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIA 774

HSP 5 Score: 93.2041 bits (230), Expect = 9.623e-19
Identity = 60/251 (23.90%), Postives = 109/251 (43.43%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  ++       I P+HI    GN+ ++RLL+                          +    I T    +  P+H A   GH  I ++++D+   +Q   K+   PIH+A    H+D ++LLL+ +   +        P+H A   GH  + ++L++      S+ +    P+H ACK  HV +++ L+    +++     G TPL +A
Sbjct:  187 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLL--------------------------DRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVA 411

HSP 6 Score: 92.0485 bits (227), Expect = 1.923e-18
Identity = 58/243 (23.87%), Postives = 108/243 (44.44%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV K L+  K  +  +   +  P+H    +G+  +++LL+                          EN+ + +   T    P+HIA  +GH   V  +++ + +     K  + P+HVA  YG V + +LLLE +       K    P+H A    +++IV++L+    +  S       P+H A K   V++ + L+    +   E + G TPL LA +  +   V ++L++
Sbjct:  441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--------------------------ENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657

HSP 7 Score: 90.1225 bits (222), Expect = 8.311e-18
Identity = 55/242 (22.73%), Postives = 106/242 (43.80%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL+                              S++        P+HIA  +G+  +V+L++D    ++T  KD   P+H A   GHV I ++LL++    + + K    PIH A +  H++ VR+L++ +   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   ++++L
Sbjct:  176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLL--------------------------NRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391

HSP 8 Score: 76.6406 bits (187), Expect = 2.041e-13
Identity = 44/207 (21.26%), Postives = 93/207 (44.93%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +H+A KQ  VEV + L+    +   E +  + P+H+    G+ E++ LL++ + +     N+                             P+H+   +GH  +  ++I +   +    +  + P+HVA  YG++ ++K LL++      + K    P+H A + GH +IV +L++N  +    + +   P+  A + G++ +   L
Sbjct:  606 LHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQAN----GNLGNKSGLT----------------------PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786

HSP 9 Score: 73.1738 bits (178), Expect = 2.262e-12
Identity = 57/274 (20.80%), Postives = 114/274 (41.61%), Query Frame = 1

Query:  163 KEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K  L ++ NP     A    +H+A ++G VE V  L+ K+ +          P+H+    G + +  LL+    + ++  N         L      N+  I  +K +  R             P+HIA  +    + + ++    +          P+H+A   GH +++ LLL         +K    P+H   + GHV +  +L+++    ++       P+H A   G++ +VKFL+ ++ ++  +   G +PL  A +  +   V ++L
Sbjct:  487 KLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLL----ERDAHPNAAGKNGLTPLHVAVHHNNLDI--VKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754

HSP 10 Score: 72.7886 bits (177), Expect = 2.818e-12
Identity = 40/124 (32.26%), Postives = 64/124 (51.61%), Query Frame = 1

Query:  541 NDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNE 912
            N  ++ T +++    +H+A   GHV ++  LL      ET  K     +H A   G  E+VR LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  V   DG TPL +AL+  +E
Sbjct:   34 NGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHE 157

HSP 11 Score: 58.151 bits (139), Expect = 1.155e-7
Identity = 34/143 (23.78%), Postives = 67/143 (46.85%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH 837
            N +K  D    N   I+T        +H+A  +GH  +V  ++  +  L+T  K     +H+A + G  ++++ L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI+
Sbjct:   24 NLDKALD-HLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLIN 165

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Match: sp|Q502K3|ANR52_DANRE (Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Danio rerio OX=7955 GN=ankrd52 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 6.738e-24
Identity = 70/275 (25.45%), Postives = 129/275 (46.91%), Query Frame = 1

Query:  163 KEFLH--SDFNPFTQCQ--AIHVACKQGFVEVVKILINKKCNI-EQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENS------------ESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDL-ALENNNEICVDMIL 933
            K FLH   + N   Q +   +H A   G V ++ +LI+   N+  ++ +W + P+H      N   + LL+    D+ +      D+ ++    I + N              S++        P+H A   G+  +VKL+++   NL  +DK + +PIH A   GH++++KLL+        +DK    P+H A  +GHV++V+ L+ N    +  N      +H AC +G   +   L++   N+   +  G TPL L A+  N  +C+++++
Sbjct:   25 KLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVW-LTPLHRAAASRNERAVGLLLRKGADVTA-----RDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLV 293

HSP 2 Score: 88.9669 bits (219), Expect = 1.912e-17
Identity = 58/243 (23.87%), Postives = 105/243 (43.21%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYAC-KTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +H A + G+ E+VK+L+NK  N+      + +P+H    +G++E+++LL+                         S+ S+     K   T P+H A   GH ++VK ++ N   +   +      +HVAC  G   +   L+         +     P+H A   T     + +LV N  +   Q+ E + P+H A   G     + LI N   ++  D  G TPL +A +  +E+ +  ++T
Sbjct:  144 LHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLV-------------------------SQGSDKSCKDKRGYT-PLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMT 360

HSP 3 Score: 76.6406 bits (187), Expect = 1.403e-13
Identity = 66/289 (22.84%), Postives = 110/289 (38.06%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEI-LRLLIAYRCDLESIANIPTDENFEKLF-----------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTE------------------TEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPL 885
                  SG+V  VK  L+      + N F    A+HVAC  G   V   L+N+  N+ Q       P+H+  +  N  + L LL+    D+    N+ + E    L             I  +N   I  +      P+H+A   GH  ++  ++ N  +          P+H+A +YG  D  + LL +                       T D +    +H A   G++E + +L+ +  +   ++   R P+HYA  +G    V  L+     +   D  G TPL
Sbjct:  210 LHAAAASGHVDVVKYLLRNGAEIDEPNAFGN-TALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADV----NMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPL 493

HSP 4 Score: 75.485 bits (184), Expect = 3.459e-13
Identity = 56/260 (21.54%), Postives = 120/260 (46.15%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNI--EQEMIWNIKPVHITCLVGNIEILRLLIAYR-----CD--LESIANIPTDENFEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCN---LQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI----HNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             A+H A   G  + +++L+    N   ++E   +I P+H+    G+ E + +LI        CD    S+  + +     +  ++  S+++  +      +  P+H+A   GH   +++++ ++     +   D +   P+ +A + GH D + LLLE     + +D+     +H     G  + +  L+ +N +  S++ + R  +H A   GH DI+  L+    H++    + D  G TP   A  + +E C++++L
Sbjct:  546 SAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLTDRHGYTPAHWAAYHGHEDCLEVLL 805

HSP 5 Score: 60.8474 bits (146), Expect = 1.539e-8
Identity = 48/187 (25.67%), Postives = 85/187 (45.45%), Query Frame = 1

Query:  406 ENFEKLFDI------DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCT-TETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNI---EKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +N E L ++      D E++ SIS        P+H+A   GH   V ++I++   +   D      +++A   GH   ++LLL  + +    E + K  P+H A   GH E +R+L+ +    +  N+   E + P+  A   GH D V  L+      +++D  G+T L        E C+  +L+
Sbjct:  558 QNLELLLEMCFNTLGDKESNGSIS--------PLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLS 736

HSP 6 Score: 58.151 bits (139), Expect = 1.100e-7
Identity = 59/269 (21.93%), Postives = 120/269 (44.61%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIK---PVHITCLVGNIEILRLLIA-----------YRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-PIHIACWKGHCNIVKLMIDNDCNLQTND----KDNWKPIHVACVYGHVDILKLLLE-NNCTTETEDKYKTRPIHYACKTGHVEIVRILVENN-CN--FESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEA 948
            +HVA   G  E +++L+  +   +   + + +   P+ +  L G+ + + LL+             R  L   A +  ++    L    S N   +S  +  Q R  +H+A   GH +I+  ++    + Q  D    +  + P H A  +GH D L++LLE   C+ +  + +   P+H A   GH     +L+E++ CN     ++ + R P+H A  +  V  ++ ++    +++  D  G++ L +A +      V ++L   +A
Sbjct:  650 LHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALL---SHNVSVLS--RDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLTDRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPFT--PLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALLLHRAKA 911

HSP 7 Score: 54.299 bits (129), Expect = 1.725e-6
Identity = 69/347 (19.88%), Postives = 139/347 (40.06%), Query Frame = 1

Query:  115 KVVKSGNVMEVKKRLKKE-FLHSDFNPFT----QCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNI-------VKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN--NCTTETEDKYKTRPIHYACKTGHVEIVRILVENN-----CN--------FESQNIEKR---------------------RPIHYACKSGHVDIVKFLIHNKCNLE---VEDIDGKTPLDLALENNNEICVDMIL-----TEIEARKKKISEMRQAFV 987
            K++ SG +  +   + KE  L + F+  T        +H A   G +E + +L++   ++ ++  +   P+H     G  + + +L+    ++          N          +  + ST      RP H +  +   +        V+ ++DN  +    +   +  +H A  +G+   L+LLLE   N   + E      P+H A ++GH E V +L+E+      C+          SQ    R                      P+H A  +GH + ++ L+ ++   +   V D +G+TPL LA+   +  CV ++L      +++ R+ + +  R A +
Sbjct:  390 KLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEV----------NERDRSGCTPLHYSAASTAFCRTDRP-HASTHQNQEDGEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVM 725

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Match: sp|Q8UVC3|INVS_CHICK (Inversin OS=Gallus gallus OX=9031 GN=INVS PE=2 SV=2)

HSP 1 Score: 105.916 bits (263), Expect = 5.529e-23
Identity = 71/257 (27.63%), Postives = 123/257 (47.86%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILIN-KKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDE------------NFEKLFDIDSENSESISTMKTVQTRPIHI-ACWKGHCNIVKLMIDN--DCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A   G V VV +L + + CN+         P+H   L+G+ +I+ LL+    +      IP+D             NF +  ++  ++  S+     ++ R   + A  KG  N+++ M+D   D ++   DK     +H A + GHV  +KLLLE N   +  D  K  P+  AC+ GH E+++ L++     +  + +   P+H+A   G+ D+ + LI NK N  V+D  G+TPL  A       C+ ++L
Sbjct:  225 LHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLL----ERNKFGTIPSDSQGATPLHYAAQSNFAETVEVFLKHP-SVKDDSDLEGRTSFMWAAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLLERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLL 476

HSP 2 Score: 82.4185 bits (202), Expect = 2.055e-15
Identity = 53/242 (21.90%), Postives = 111/242 (45.87%), Query Frame = 1

Query:  220 ACKQGFVEVVKILINKKCNIEQEMI--WNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH-NKCNLEVEDIDGK-TPLDLALENNNEICVDMIL 933
            A  +G   V++ +++ K +I+  M   +    +H   L G++  ++LL+                          E +  +  +  ++  P+  AC  GH  +++ +I     +   D+D   P+H A + G+ D+ ++L+EN      +D     P+  A   G++  + +L+ENN +   Q+ E R  +H+ C +G++D +K L+  +     +E+ + + TPLD AL   +   +  +L
Sbjct:  329 AAGKGSDNVIRTMLDLKLDIDINMTDKYAGTALHAAALSGHVSTVKLLL--------------------------ERNAQVDALDVMKHTPLFRACEMGHKEVIQTLIKGGARVDLVDQDGHSPLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMVVLLENNADPNIQDKEGRTALHWLCNNGYLDAIKLLLGFDAFPNHMENSEERYTPLDYALLGEHHEVIQFML 544

HSP 3 Score: 78.5666 bits (192), Expect = 4.368e-14
Identity = 68/274 (24.82%), Postives = 117/274 (42.70%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVY---GHVDILKLLLENNCTTET---EDKYKTRPIHYACKTGHVEIVRILVE-NNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPG 1005
            A+H+A ++G    +K+L+ ++ N  Q+ +  + P+H+T    + + L LL+ +    E               D    N ++           +H + +  +   VKL+I +D N+   D +   P+H A        +  +K +LE   T      +D     P+H+A   G+V +V +L     CN  S +   R P+H+A   GH  IV  L+  NK      D  G TPL  A ++N    V++ L     +     E R +F+ A   G
Sbjct:   84 ALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHMAPGE--------------VDTQDRNKQTA----------LHWSAYYNNPEHVKLLIKHDSNIGIPDIEGKIPLHWAANNKDPSAIHTVKCILEAAPTESLLNWQDYEGRTPLHFAVADGNVAVVDVLTSYEGCNVTSYDNLFRTPLHWAALLGHAQIVHLLLERNKFGTIPSDSQGATPLHYAAQSNFAETVEVFLKHPSVKDDSDLEGRTSFMWAAGKG 333

HSP 4 Score: 55.0694 bits (131), Expect = 1.023e-6
Identity = 29/120 (24.17%), Postives = 58/120 (48.33%), Query Frame = 1

Query:  586 IHVACVYG-HVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEI 942
            +H A V G    +LKL+  N+   + ED++   P+ Y      V+    L++   +    +  +R  +H A + G+   +K L+  + N   +D++G TPL L   + +  C+ ++L  +
Sbjct:   18 VHAAAVNGDKSTLLKLIAGNSELKDKEDQFGRTPLMYCVLADRVDCAEALLKAGADVNRADRSRRTALHLAAQKGNYRFMKLLLARRGNWMQKDLEGMTPLHLTTRHKSPKCLALLLKHM 137

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Match: sp|P53355|DAPK1_HUMAN (Death-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=DAPK1 PE=1 SV=6)

HSP 1 Score: 105.531 bits (262), Expect = 7.724e-23
Identity = 80/325 (24.62%), Postives = 150/325 (46.15%), Query Frame = 1

Query:   97 NLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTV 1038
            N+ + + ++K G+ ++V+ +                 A++ A + G V+ +K L   KC ++ +       +H+    G+ ++ +LL    C   S  NI   E    L         S++           ++ R    P+  A  +G+ +IV+ + ++  +L   DKD    +H+A     ++++K LL   C  + +D++   P+H ACK G++ IV  L E NCN +  N   R P+H A  +G +D+V++L     ++E    DGKT  DLA    +E    ++     AR +K +  R  F+   RP  + + R+K+ +
Sbjct:  391 NIQILQLLIKRGSRIDVQDK-------------GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLL----CSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL-----ARLRKDTH-RGLFIQQLRPTQNLQPRIKLKL 692

HSP 2 Score: 84.7297 bits (208), Expect = 4.962e-16
Identity = 43/136 (31.62%), Postives = 71/136 (52.21%), Query Frame = 1

Query:  478 TRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPL 885
            T P+ IA   G+  I++L+I     +   DK     ++ A  +GHVD LK L EN C  + +DK     +H A + GH ++ ++L     N   Q+ E+  P+H A   G+  + K L    CN+ +++ +G+TPL
Sbjct:  380 TPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL 515

HSP 3 Score: 82.0333 bits (201), Expect = 3.025e-15
Identity = 56/211 (26.54%), Postives = 87/211 (41.23%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            P+ I    GNI+IL+LLI                          +    I       +  ++ A   GH + +K + +N C L   DK     +HVA  YGH D+ +LL         +DK +  P+H A   G+  + + L E  CN   +N E   P+  A   G+ DIV+ L  +  +L   D DG   L LA+       +  +L++
Sbjct:  382 PLLIAAGCGNIQILQLLI--------------------------KRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 566

HSP 4 Score: 64.3142 bits (155), Expect = 1.288e-9
Identity = 30/110 (27.27%), Postives = 59/110 (53.64%), Query Frame = 1

Query:  565 DKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +K    P+ +A   G++ IL+LL++     + +DK  +  +++A + GHV+ ++ L EN C  + ++      +H A + GH D+ + L     N  ++D + +TPL  A
Sbjct:  376 NKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCA 485

HSP 5 Score: 55.4546 bits (132), Expect = 7.666e-7
Identity = 26/85 (30.59%), Postives = 49/85 (57.65%), Query Frame = 1

Query:  640 NNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +N      +K+ T P+  A   G+++I+++L++     + Q+      +++A + GHVD +KFL  NKC L+V+D  G+  L +A
Sbjct:  368 SNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVA 452

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 1.036e-22
Identity = 67/287 (23.34%), Postives = 133/287 (46.34%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V  V + L++E  + D        A+H+A   G  EVVK+L+    N+  +      P+++     ++E++R L+    D  +  ++ T++ F  L     +  + +        T   V+   +HIA  K       L++ ND N     K  + P+H+A  YG++++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H   +SGH  +V+ L+     +  +  +G +PL +A + ++  CV ++L
Sbjct:   56 NGLNALHLASKEGHVEVVSELLQRE-ANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLL----DNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLL 337

HSP 2 Score: 97.0561 bits (240), Expect = 5.369e-20
Identity = 56/229 (24.45%), Postives = 108/229 (47.16%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            A+HVA   G  +V K+L++KK +   + +    P+HI C    I ++ LL+ +   ++++                   +ES  T       PIH+A + GH NIV  ++ +  +  T +      +H+A   G  ++++ L+++    E + K    P+H + + G  +IV+ L++   +  +       P+H A + GH D+  FL+ +  +L +    G TPL +A
Sbjct:  353 ALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAV-------------------TESGLT-------PIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVA 555

HSP 3 Score: 96.2857 bits (238), Expect = 7.636e-20
Identity = 55/241 (22.82%), Postives = 114/241 (47.30%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNE 912
            +H   + G  +VV++L+++   I  +    + P+H+     ++  ++LL+ +   ++ + N       +       K+  +  +   S +        P+HIAC K    +++L++ +  ++Q   +    PIHVA   GHV+I+  L+ +  +  T +      +H A ++G  E+VR LV++    E++  + + P+H + + G  DIV+ L+    +       G TPL LA    +E
Sbjct:  288 LHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHE 528

HSP 4 Score: 93.5893 bits (231), Expect = 6.019e-19
Identity = 52/245 (21.22%), Postives = 117/245 (47.76%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ +L+     + S         ++ T  +      +  +++  +  +       +H+A   GH  + K+++D   +      + + P+H+AC    + +++LLL++  + +   +    PIH A   GHV IV  L+ +  +  + N+     +H A +SG  ++V++L+ +   +E +  D +TPL ++
Sbjct:  245 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHIS 489

HSP 5 Score: 93.2041 bits (230), Expect = 7.886e-19
Identity = 57/255 (22.35%), Postives = 113/255 (44.31%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A ++   +   +L+    N + E      P+HI    GNI +  LL+                N     D  + N  +          P+H+A  +G+ N+VKL++D    +    +D   P+H     GH  ++++LL+ +    ++ K    P+H A +  H+  V++L+++N   +    +    +H A   GH  + K L+  K +   + ++G TPL +A + N    ++++L
Sbjct:  175 LLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLL----------------NRAAAVDFTARNDIT----------PLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLL 403

HSP 6 Score: 89.3521 bits (220), Expect = 1.335e-17
Identity = 62/242 (25.62%), Postives = 110/242 (45.45%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI-------AYRCDLESIANIPTDENFEKL--FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
            A+H+A + G  EVV+ L+     +E +   +  P+HI+  +G  +I++ L+       A      +  ++   E  E +  F +D   S SI+T K     P+H+A   G   +  L++    +     K    P+HVA  Y +  +  LLL+   +     K    P+H A K   ++I   L+E   +  +   +    +H A + GHVD+V  L+    N+ + +  G TPL LA + +
Sbjct:  452 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFT--PLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQED 691

HSP 7 Score: 83.9593 bits (206), Expect = 9.375e-16
Identity = 53/239 (22.18%), Postives = 108/239 (45.19%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTM-------KTVQTR----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G +EV  +L+ K  + +      + P+H+     N ++  LL+    D  +  +      +  L     +N   I+T            TR     +H+A  +GH ++V L++  + N+  ++K    P+H+A     V++ ++L+      + + K    P+H  C  G+++IV  L++++    ++       +H A + GH  I+  L+ N  +     ++G T L +A
Sbjct:  552 LHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLL----DQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIA 786

HSP 8 Score: 80.8777 bits (198), Expect = 8.272e-15
Identity = 50/248 (20.16%), Postives = 106/248 (42.74%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A ++G  +V   L++   ++         P+H+    G +E+  LL+      ++         ++    + +K+  +  +   S          P+HIA  K   +I   +++   +     +     +H+A   GHVD++ LLL  N      +K    P+H A +   V +  +LV    + ++Q      P+H  C  G++ IV FL+ +   +  +  +G T L  A +  +   ++++L
Sbjct:  519 LHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLL 766

HSP 9 Score: 75.485 bits (184), Expect = 4.792e-13
Identity = 39/146 (26.71%), Postives = 73/146 (50.00%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A   GH       I N  ++   +++    +H+A   GHV+++  LL+     +   K     +H A   G  E+V++LV N  N  +Q+     P++ A +  H+++V+FL+ N  +  +   DG TPL +AL+  ++  V ++L
Sbjct:   31 AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL 176

HSP 10 Score: 69.3218 bits (168), Expect = 3.520e-11
Identity = 40/214 (18.69%), Postives = 94/214 (43.93%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +HVA      +V  +L+++  +          P+HI      ++I   L+ Y  D  ++        ++   E    +  +    + +++        P+H+A  +   N+ +++++   ++    K  + P+HV C YG++ I+  LL+++     + K     +H A + GH  I+ +L++NN +     +     +  A + G++ +V  L
Sbjct:  585 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTL 798

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Match: Q16FI9 (AAEL014742-PA (Fragment) OS=Aedes aegypti OX=7159 GN=AAEL014742 PE=4 SV=1)

HSP 1 Score: 164.466 bits (415), Expect = 1.907e-40
Identity = 78/240 (32.50%), Postives = 141/240 (58.75%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIE--QEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            +H+A + G++EVVK+LI+   N++  Q+  W   P+H+    G++E+++LLI  R ++++  N       + +     ++  +  EN  ++ T K     P+H A   GH  +VK +IDN  N+ T   + W P+HVA   GH++++KLL+EN    +T+      P+H+A + GH+E+V+ L++N  N ++   E   P+H A ++GH+++VK LI N+ N++ +   G TPL +A +N
Sbjct:   56 LHLAAENGYLEVVKLLIDNGANVDTTQDEGW--TPLHLAAENGHLEVVKLLIDNRANVDTKKNGGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHLAAENGHLEVVKLLIENRANVDTKKNGGWTPLHVASQN 293

HSP 2 Score: 162.54 bits (410), Expect = 9.934e-40
Identity = 81/272 (29.78%), Postives = 151/272 (55.51%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +EV K L +   + D         ++VA   G +EVVK+LIN + N++        P+++    G++E+++LLI  + ++++  N       + +     ++  +  +N  ++ T K     P+++A   GH  +VKL+IDN  N+ T D + W P+HVA   GH++++KLL+EN    +T       P+H+A + GH+E+V++L++N  N ++   E   P+H A ++GH+++VK LI N+ N++     G TPL  A +N +   V +++
Sbjct:  439 LEVVKLLIENRANVDTTQNEGWTPLYVASINGHLEVVKLLINNRANVDTTQNEGWTPLYVASKNGHLEVVKLLIDNKANVDTTQNEGWTPLHVASQNGHLEVVKLLIDNRANVDTTKNKGITPLYVASKNGHLEVVKLLIDNKANVDTTDNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVDTTQNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLI 710

HSP 3 Score: 161.77 bits (408), Expect = 1.931e-39
Identity = 80/259 (30.89%), Postives = 144/259 (55.60%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +EV K L     + D         +HVA + G +EVVK+LI+ + N++      I P+++    G++E+++LLI  + ++++  N       + +     ++  +  EN  ++ T +     P+H A   GH  +VKL+IDN  N+ T   + W P+HVA   GH++++KLL+EN    +T       P+H+A + GH+E+V++L++N  N ++   E   P+H A ++GH+++VK LI N+ N++     G TPL +A
Sbjct:  505 LEVVKLLIDNKANVDTTQNEGWTPLHVASQNGHLEVVKLLIDNRANVDTTKNKGITPLYVASKNGHLEVVKLLIDNKANVDTTDNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVDTTQNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVDTTQNEGWTPLHVASQNGHLEVVKLLIDNRANVDTTQNKGITPLYVA 763

HSP 4 Score: 161.384 bits (407), Expect = 2.253e-39
Identity = 76/248 (30.65%), Postives = 143/248 (57.66%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA + G ++VVK+LI+   N++ E      P+H+    G +E+++LLI    ++++  +       +  +    ++  +  +N  ++ T K     P+H+A   GH  +VKL+I+N  N+ T   + W P+H A   GH++++K L++N    +T       P+H A + GH+E+V++L+EN  N +++  E   P+H+A ++GH+++VKFLI N+ N++    +G TPL LA EN +   V +++
Sbjct:   23 LHVASQNGHLKVVKLLIDNGANVDTEGDEGWTPLHLAAENGYLEVVKLLIDNGANVDTTQDEGWTPLHLAAENGHLEVVKLLIDNRANVDTKKNGGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHLAAENGHLEVVKLLI 270

HSP 5 Score: 159.844 bits (403), Expect = 9.179e-39
Identity = 86/283 (30.39%), Postives = 153/283 (54.06%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCD-----LESIANIPTDEN-------------FEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +EV K L     + D   +     +HVA + G +EVVK+LI+ K N++      I P+H     G++E+++LLI  R +     +E+ AN+ T +N               ++  +  EN  ++ T +     P+H A   GH  +VKL+I+N  N+ T   + W P++VA + GH++++KLL+ N    +T       P++ A K GH+E+V++L++N  N ++   E   P+H A ++GH+++VK LI N+ N++     G TPL +A +N +   V +++
Sbjct:  296 LEVVKFLIDNRANVDTTQYEGWTPLHVASQNGHLEVVKLLIDNKANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIENRANVGTTQNEGWTPLHFASRNGHLEVVKLLIENRANVDTTQNEGWTPLYVASINGHLEVVKLLINNRANVDTTQNEGWTPLYVASKNGHLEVVKLLIDNKANVDTTQNEGWTPLHVASQNGHLEVVKLLIDNRANVDTTKNKGITPLYVASKNGHLEVVKLLI 578

HSP 6 Score: 159.458 bits (402), Expect = 1.213e-38
Identity = 81/272 (29.78%), Postives = 145/272 (53.31%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +EV K L     + D         +HVA + G +EVVK+LI  + N++ +      P+H     G++E+++ LI  R ++++  +       + +     ++  +  EN  ++ T K     P+H A   GH  +VK +IDN  N+ T   + W P+H+A   GH++++KLL+EN    +T+      P+H A + GH+E+V+ L++N  N ++   E   P+H A ++GH+++VK LI NK N++     G TPL  A +N +   V +++
Sbjct:   98 LEVVKLLIDNRANVDTKKNGGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHLAAENGHLEVVKLLIENRANVDTKKNGGWTPLHVASQNGHLEVVKFLIDNRANVDTTQYEGWTPLHVASQNGHLEVVKLLIDNKANVDTTQNKGITPLHFASQNGHLEVVKLLI 369

HSP 7 Score: 145.591 bits (366), Expect = 6.674e-34
Identity = 68/227 (29.96%), Postives = 129/227 (56.83%), Query Frame = 1

Query:  244 VVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            +VK LI+   NI+        P+H+    G++++++LLI    ++++  +       +  +  + ++  +  +N  ++ T +     P+H+A   GH  +VKL+IDN  N+ T     W P+HVA   GH++++KLL+EN    +T+      P+H+A + GH+E+V+ L++N  N ++   E   P+H A ++GH+++VK LI N+ N++ +  +G TPL  A +N
Sbjct:    1 MVKFLIDHNANIDTANNGGRTPLHVASQNGHLKVVKLLIDNGANVDTEGDEGWTPLHLAAENGYLEVVKLLIDNGANVDTTQDEGWTPLHLAAENGHLEVVKLLIDNRANVDTKKNGGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGWTPLHVASQNGHLEVVKLLIENRANVDTKKNEGWTPLHFASQN 227

HSP 8 Score: 144.05 bits (362), Expect = 2.437e-33
Identity = 95/335 (28.36%), Postives = 170/335 (50.75%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIE--QEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCN---LEVE---DID-----GKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVD---APRPGPSTKERMKVTVKARIET 1056
            +EV K L +   + D         +H A + G +EVVK LI+ + N++  Q+  W   P+H+    G++E+++LLI  R ++++  N    E +  L             F ID  N  ++ T +     P+H+A   GH  +VKL+I+N  N+ T     W P+HVA   GH++++K L++N    +T       P+H A + GH+E+V++L++N  N ++   +   P+H+A ++GH+++VK LI N+ N   L +E   ++D     G TPL  A +N +   V ++   IE R    +   + +     A R G     ++ +  +A ++T
Sbjct:  131 LEVVKLLIENRANVDTKKNEGWTPLHFASQNGHLEVVKFLIDNRANVDTTQDEGW--TPLHVASQNGHLEVVKLLIENRANVDTKKN----EGWTPLHFASQNGHLEVVKFLID--NRANVDTTQDEGWTPLHLAAENGHLEVVKLLIENRANVDTKKNGGWTPLHVASQNGHLEVVKFLIDNRANVDTTQYEGWTPLHVASQNGHLEVVKLLIDNKANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLL---IENRANVGTTQNEGWTPLHFASRNGHLEVVKLLIENRANVDT 454

HSP 9 Score: 135.961 bits (341), Expect = 1.368e-30
Identity = 71/252 (28.17%), Postives = 134/252 (53.17%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDG 873
            +EV K L     + D         ++VA K G +EVVK+LI+ K N++        P+H+    G++E+++LLI  R ++++  N         +     ++  +  +N  ++ T +     P+H+A   GH  +VKL+I+N  N+ T       P+H A   GH++++KLL++N    +T       P+H A + GH+E+V++L++N  N ++   +   P++ A  +GH+++VK LI N+ N++    +G
Sbjct:  538 LEVVKLLIDNRANVDTTKNKGITPLYVASKNGHLEVVKLLIDNKANVDTTDNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVDTTQNEGWTPLHVASQNGHLEVVKLLIENRANVDTTQNKGITPLHFASQNGHLEVVKLLIDNRANVDTTQNEGWTPLHVASQNGHLEVVKLLIDNRANVDTTQNKGITPLYVASINGHLEVVKLLIDNRANVDTTQNEG 789

HSP 10 Score: 105.145 bits (261), Expect = 2.030e-20
Identity = 46/138 (33.33%), Postives = 86/138 (62.32%), Query Frame = 1

Query:  520 IVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +VK +ID++ N+ T +     P+HVA   GH+ ++KLL++N    +TE      P+H A + G++E+V++L++N  N ++   E   P+H A ++GH+++VK LI N+ N++ +   G TPL +A +N +   V +++
Sbjct:    1 MVKFLIDHNANIDTANNGGRTPLHVASQNGHLKVVKLLIDNGANVDTEGDEGWTPLHLAAENGYLEVVKLLIDNGANVDTTQDEGWTPLHLAAENGHLEVVKLLIDNRANVDTKKNGGWTPLHVASQNGHLEVVKLLI 138

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Match: J9HSB7 (AAEL017480-PA (Fragment) OS=Aedes aegypti OX=7159 GN=AaeL_AAEL017480 PE=4 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 9.128e-38
Identity = 83/286 (29.02%), Postives = 141/286 (49.30%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPER 1068
            +H A   G +EVVK+LI+   N++        P+H     G++E+++LLI  R      AN+ T +N E                      P+H A   G   +VK +IDN  N+ T D + W P+H A   GH++++KLL++N    +T       P+HYA + G +E+V+ +++N  N ++ + E   P+HYA ++G +++VKFLI N  N++    +G TPL  A  N +   V +++ +        +E      DA   G     ++ +   A ++TK  R
Sbjct:   13 LHYASLNGHLEVVKLLIDNGANVDTTQNKGWTPLHFASQNGHLEVVKLLIDNR------ANVDTTQNEEWT--------------------PLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRNEGWTPLHYASRNGRLEVVKFMIDNGANVDTTDNEGWTPLHYASRNGRLEVVKFLIDNGANVDTTQNEGWTPLHYASRNGHLEVVKLLIDDEANVDTTDNEGWTPLHDASLIGHLEVVKLLIDNGANVDTKNTR 272

HSP 2 Score: 140.198 bits (352), Expect = 4.441e-34
Identity = 72/262 (27.48%), Postives = 133/262 (50.76%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            +EV K L     + D         +H A + G +EVVK+LI+ + N++        P+H     G +E+++ LI    ++++  N         +     ++  +  +N  ++ T +     P+H A   G   +VK MIDN  N+ T D + W P+H A   G ++++K L++N    +T       P+HYA + GH+E+V++L+++  N ++ + E   P+H A   GH+++VK LI N  N++ ++    T L +A +N
Sbjct:   22 LEVVKLLIDNGANVDTTQNKGWTPLHFASQNGHLEVVKLLIDNRANVDTTQNEEWTPLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRNEGWTPLHYASRNGRLEVVKFMIDNGANVDTTDNEGWTPLHYASRNGRLEVVKFLIDNGANVDTTQNEGWTPLHYASRNGHLEVVKLLIDDEANVDTTDNEGWTPLHDASLIGHLEVVKLLIDNGANVDTKNTRRPTSLHIASQN 283

HSP 3 Score: 139.043 bits (349), Expect = 1.020e-33
Identity = 78/278 (28.06%), Postives = 140/278 (50.36%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +EV K L     + D     +   +H A + G +EVVK LI+   N++        P+H     G++E+++LLI    ++++  N    E +  L             F ID  N  ++ T       P+H A   G   +VK +IDN  N+ T   + W P+H A   GH++++KLL+++    +T D     P+H A   GH+E+V++L++N  N +++N  +   +H A ++G +++VK LI N  N++ ++  G T L +A  N +   V +++
Sbjct:   55 LEVVKLLIDNRANVDTTQNEEWTPLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRN----EGWTPLHYASRNGRLEVVKFMID--NGANVDTTDNEGWTPLHYASRNGRLEVVKFLIDNGANVDTTQNEGWTPLHYASRNGHLEVVKLLIDDEANVDTTDNEGWTPLHDASLIGHLEVVKLLIDNGANVDTKNTRRPTSLHIASQNGRLEVVKLLIDNGANVDTKNTRGSTSLHIASRNGHLEVVKLLI 326

HSP 4 Score: 138.658 bits (348), Expect = 1.332e-33
Identity = 71/252 (28.17%), Postives = 132/252 (52.38%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKL-------------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLE 855
            +EV K L     + D         +H A + G +EVVK+LI+   N++        P+H     G +E+++ +I    ++++  N    E +  L             F ID  N  ++ T +     P+H A   GH  +VKL+ID++ N+ T D + W P+H A + GH++++KLL++N    +T++  +   +H A + G +E+V++L++N  N +++N      +H A ++GH+++VK LI N  N++
Sbjct:   88 LEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRNEGWTPLHYASRNGRLEVVKFMIDNGANVDTTDN----EGWTPLHYASRNGRLEVVKFLID--NGANVDTTQNEGWTPLHYASRNGHLEVVKLLIDDEANVDTTDNEGWTPLHDASLIGHLEVVKLLIDNGANVDTKNTRRPTSLHIASQNGRLEVVKLLIDNGANVDTKNTRGSTSLHIASRNGHLEVVKLLIDNGANVD 333

HSP 5 Score: 137.502 bits (345), Expect = 4.071e-33
Identity = 63/199 (31.66%), Postives = 106/199 (53.27%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            P+H   L G++E+++LLI                          +N  ++ T +     P+H A   GH  +VKL+IDN  N+ T   + W P+H A   G ++++K L++N    +T D     P+HYA + GH+E+V++L++N  N ++   E   P+HYA ++G +++VKF+I N  N++  D +G TPL  A  N
Sbjct:   12 PLHYASLNGHLEVVKLLI--------------------------DNGANVDTTQNKGWTPLHFASQNGHLEVVKLLIDNRANVDTTQNEEWTPLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRNEGWTPLHYASRNGRLEVVKFMIDNGANVDTTDNEGWTPLHYASRN 184

HSP 6 Score: 127.487 bits (319), Expect = 1.680e-29
Identity = 54/151 (35.76%), Postives = 89/151 (58.94%), Query Frame = 1

Query:  451 SISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            ++ T +     P+H A   GH  +VKL+IDN  N+ T     W P+H A   GH++++KLL++N    +T    +  P+HYA + G +E+V+ L++N  N ++ + E   P+HYA ++GH+++VK LI N  N++    +G TPL  A  N
Sbjct:    1 NVDTTRNEGWTPLHYASLNGHLEVVKLLIDNGANVDTTQNKGWTPLHFASQNGHLEVVKLLIDNRANVDTTQNEEWTPLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTTRNEGWTPLHYASRN 151

HSP 7 Score: 106.686 bits (265), Expect = 5.411e-22
Identity = 44/128 (34.38%), Postives = 80/128 (62.50%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N+ T   + W P+H A + GH++++KLL++N    +T       P+H+A + GH+E+V++L++N  N ++   E+  P+HYA ++G +++VKFLI N  N++  D +G TPL  A  N +   V +++
Sbjct:    1 NVDTTRNEGWTPLHYASLNGHLEVVKLLIDNGANVDTTQNKGWTPLHFASQNGHLEVVKLLIDNRANVDTTQNEEWTPLHYASRNGRLEVVKFLIDNGANVDTTDNEGWTPLHYASRNGHLEVVKLLI 128

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Match: A0A1X7T5X6 (Uncharacterized protein OS=Amphimedon queenslandica OX=400682 PE=4 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 5.016e-37
Identity = 101/290 (34.83%), Postives = 160/290 (55.17%), Query Frame = 1

Query:   82 VKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINK-KCNIEQEMIWNIKPVHITCLVGNIEILR-LLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSE-SISTMKTVQTRPIHIACWKGHCNIVK-LMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN-NCTTETEDKYKTRPIHYACKTGHVEIVRILV-ENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLALENNN 909
            V+ N+N     K  +SGNV  V   +  +  + +         +H AC++G  E+VKIL N  +CNIE E  +N +P+H  C  GN++I+R L+I   CD+ +I        +   ++   ++  I + +S+ ++        RP+H AC  G+ +IV  L+ID  C++    KD + P+H AC  GH +I+K+L  +  C  E ED +  RP+H AC++G+V+IVR LV + +C+  +       P+HYAC+ GH +IVK L  H++CNLE E      PL  A E+ N
Sbjct:   73 VEDNSNDRPLHKACESGNVDIVCHLVIDKHCNVNAKGRNGYTPLHYACEKGHFEIVKILTNHPQCNIEVEGSFNDRPLHKACESGNVDIVRHLVIDKHCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGNFNDRPLHKACESGNVDIVHHLVIDKHCDVNAKGKDGYTPLHYACEKGHFEIVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGSFNDRPLHKACESGN 362

HSP 2 Score: 153.68 bits (387), Expect = 1.519e-36
Identity = 95/281 (33.81%), Postives = 157/281 (55.87%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINK-KCNIEQEMIWNIKPVHITCLVGNIEILR-LLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSE-SISTMKTVQTRPIHIACWKGHCNIVK-LMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN-NCTTETEDKYKTRPIHYACKTGHVEIVRILV-ENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLALENNN 909
              K  +SGNV  V+  +  +    +         +H AC++G  E VKIL N  +CNIE +  WN +P+H  C  GN++I+R L+I   CD+ +I        +   ++   ++  I + +S+ ++    +   RP+H AC  G+ +IV+ L+ID  C++   D+  + P+H AC  GH + +K+L  +  C  E ED +  RP+H AC++G+V+IVR LV + +C+  ++      P+HYAC+ GH +IVKFL  H +CN + ED+    PL  A ++ N
Sbjct:  558 LHKACESGNVDIVRHLVINKHCDVNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAKDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGSFNDRPLHKACESGNVDIVRHLVIDKHCDVNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAKGRNGYTPLHYACEKGHFEIVKFLTNHPQCNTKAEDVCDDRPLHKACKSRN 838

HSP 3 Score: 149.058 bits (375), Expect = 6.349e-35
Identity = 93/269 (34.57%), Postives = 147/269 (54.65%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINK-KCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDN-DCNLQTNDKDNWKPIHVACVYGHVDILK-LLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENN-CNFESQNIEKRRPIHYACKSGHVDIVKFLIHNK-CNLEVEDIDGKTPLDLALE 900
              K  +SGNV  V+  +  +    +         +H AC++G  E VKIL N  +CNIE E  WN +P+H  C  GN++I+R L+                  +K  D++++     +        P+H AC KGH  IVK++ ++  CN++  D    +P+H AC  G+VDI++ L+++ +C    + +    P+HYAC+ GH EIV+IL  ++ CN E++     RP+H AC+SG+VDIV+ L+ NK C++  +D  G TPL  A E
Sbjct:  354 LHKACESGNVDIVRHLVINKHCDVNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLV-----------------IDKHCDVNAKGRNGYT--------PLHYACEKGHFEIVKILTNHPQCNIEAEDYSKDRPLHNACESGNVDIVRHLVIDKHCDVNAKGRIGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGSFNDRPLHKACESGNVDIVRHLVINKHCDVNAKDRIGYTPLHYACE 597

HSP 4 Score: 146.747 bits (369), Expect = 3.943e-34
Identity = 94/272 (34.56%), Postives = 149/272 (54.78%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNP--FTQCQAIHVACKQGFVEVVKILIN-KKCNIEQEMIWNIKPVHITCLVGNIEILR-LLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDN-DCNLQTNDKDNWKPIHVACVYGHVDILK-LLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN-NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNK-CNLEVEDIDGKTPLDLALE 900
              K  +SGNV  V+  +  +  H D N   +     +H AC++G  E+VKIL N  +CN+E E  +N +P+H  C  GN++I+R L+I   CD                          ++    +   P+H AC KGH   VK++ ++  CN++  D  N +P+H AC  G+VDI++ L+++ +C    + +    P+HYAC+ GH EIV+IL  +  CN E+++  K RP+H AC+SG+VDIV+ L+ +K C++  +   G TPL  A E
Sbjct:  286 LHKACESGNVDIVRHLVIDK--HCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGSFNDRPLHKACESGNVDIVRHLVINKHCD--------------------------VNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAKGRNGYTPLHYACEKGHFEIVKILTNHPQCNIEAEDYSKDRPLHNACESGNVDIVRHLVIDKHCDVNAKGRIGYTPLHYACE 529

HSP 5 Score: 141.739 bits (356), Expect = 1.676e-32
Identity = 95/277 (34.30%), Postives = 147/277 (53.07%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINK-KCNIEQEMIWNIKPVHITCLVGNIEILR-LLIAYRCDLESIAN---IP-----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVK-LMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN-NCTTETEDKYKTRPIHYACKTGHVEIVRILV-ENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLAL 897
              K  +SGNV  V+  +  +    +         +H AC++G  E VKIL N  +CNIE E  WN +P+H  C  GN++I+R L+I   CD+ +       P        +FE +  + +    +         RP+H AC   + +IV+ L+ID   ++    +D + P+H AC  GH +I+K+L  +  C TE ED Y  R +H AC+ G ++IVR LV + + +  ++      P+HYAC+ GH +IVK L  H +CN+E E+ D K PL LA+
Sbjct:  694 LHKACESGNVDIVRHLVIDKHCDVNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAKGRNGYTPLHYACEKGHFEIVKFLTNHPQCNTKAEDVCDDRPLHKACKSRNVDIVRYLVIDKHRDVNAKGRDGYTPLHYACEKGHFEIVKILTNHPQCNTEAEDVYDDRSLHKACEFGRLDIVRYLVIDKHRDVNAKGRNGYTPLHYACEKGHFEIVKILTNHPQCNIEAENNDNKWPLHLAI 970

HSP 6 Score: 140.969 bits (354), Expect = 3.018e-32
Identity = 94/281 (33.45%), Postives = 151/281 (53.74%), Query Frame = 1

Query:   82 VKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNP--FTQCQAIHVACKQGFVEVVKILIN-KKCNIEQEMIWNIKPVHITCLVGNIEILR-LLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDN-DCNLQTNDKDNWKPIHVACVYGHVDILK-LLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN-NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKC-NLEVEDIDGKTPLDLALE 900
             K N N     K  +SGNV  V+  +  +  H D N   +     +H AC++G  E+VKIL N  +CN+E E  +N +P+H  C  GN++I+R L+I   CD                          ++    +   P+H AC KGH   VK++ ++  CN++  D  N +P+H AC  G+VDI++ L+++ +C    + +    P+HYAC+ GH EIV+ L  +  CN +++++   RP+H ACKS +VDIV++L+ +K  ++  +  DG TPL  A E
Sbjct:  617 AKDNWNNRPLHKACESGNVDIVRHLVIDK--HCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGSFNDRPLHKACESGNVDIVRHLVIDKHCD--------------------------VNAKDRIGYTPLHYACEKGHFETVKILTNHPQCNIEAEDNWNNRPLHKACESGNVDIVRHLVIDKHCDVNAKGRNGYTPLHYACEKGHFEIVKFLTNHPQCNTKAEDVCDDRPLHKACKSRNVDIVRYLVIDKHRDVNAKGRDGYTPLHYACE 869

HSP 7 Score: 133.65 bits (335), Expect = 9.753e-30
Identity = 85/247 (34.41%), Postives = 140/247 (56.68%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINK-KCNIEQEMIWNIKPVHITCLVGNIEIL-RLLIAYRCDLESIAN---IP-----TDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVK-LMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENN-CTTETEDKYKTRPIHYACKTGHVEIVRILV-ENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLALENNN 909
            +H AC++G  E+V+IL +  +CNIE E   N +P+H  C  GN++I+  L+I   C++ +       P        +FE +  + +    +I    +   RP+H AC  G+ +IV+ L+ID  C++     + + P+H AC  GH +I+K+L  ++ C  E E  +  RP+H AC++G+V+IV  LV + +C+  ++  +   P+HYAC+ GH +IVK L  H +CN+E ED     PL  A E+ N
Sbjct:   48 LHYACEEGCFEIVRILTDHPQCNIEVEDNSNDRPLHKACESGNVDIVCHLVIDKHCNVNAKGRNGYTPLHYACEKGHFEIVKILTNHPQCNIEVEGSFNDRPLHKACESGNVDIVRHLVIDKHCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGNFNDRPLHKACESGNVDIVHHLVIDKHCDVNAKGKDGYTPLHYACEKGHFEIVKILTNHPQCNIEAEDNWNNRPLHKACESGN 294

HSP 8 Score: 121.709 bits (304), Expect = 8.513e-26
Identity = 81/245 (33.06%), Postives = 130/245 (53.06%), Query Frame = 1

Query:  193 FTQCQAIHVACKQGFVEVVK-ILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAY-RCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIV-KLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN-NCTTETEDKYKTRPIHYACKTGHVEIVRILV-ENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI-HNKCNLEVEDIDGKTPLDLALENNN 909
            F   +++  ACK   V++V+ ++I+K C++  +      P+H  C  G  EI+R+L  + +C++E                   +NS           RP+H AC  G+ +IV  L+ID  CN+    ++ + P+H AC  GH +I+K+L  +  C  E E  +  RP+H AC++G+V+IVR LV + +C+  +       P+HYAC+ GH +IVK L  H++CNLE E      PL  A E+ N
Sbjct:    8 FEDRRSLVYACKFRNVDIVRHLVIDKHCDVNAKGRNGYTPLHYACEEGCFEIVRILTDHPQCNIEV-----------------EDNSND---------RPLHKACESGNVDIVCHLVIDKHCNVNAKGRNGYTPLHYACEKGHFEIVKILTNHPQCNIEVEGSFNDRPLHKACESGNVDIVRHLVIDKHCDVNAIGWNGYTPLHYACEKGHFEIVKILTNHSQCNLEAEGNFNDRPLHKACESGN 226

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Match: Q16FR1 (AAEL014668-PA (Fragment) OS=Aedes aegypti OX=7159 GN=AAEL014668 PE=4 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 7.761e-37
Identity = 77/251 (30.68%), Postives = 140/251 (55.78%), Query Frame = 1

Query:  202 CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN---IPTDENFEK----LFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            C  +H A + G +E+VK+LI+ + N++        P+H     G+I++++LLI  R ++++  N    P  +  E     +  +  +N  ++ T ++    P+H A   G+  +VKL+IDN  N+ T   + W P+H A   G +D++KLL++N    +T       P+HYA + G++E+V++L++N  N ++   E   P+HYA ++G +D+VK LI N+ N++    +G TPL  A  N N   V +++
Sbjct:   33 CTPLHYASRNGNLEMVKLLIDNRANVDTTQNEGWTPLHYASQNGHIDVVKLLIDNRANVDTTQNEGCTPLHKAAENGHLDVVKLLIDNKANVDTAQSEGWTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASQNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLI 283

HSP 2 Score: 153.295 bits (386), Expect = 1.686e-36
Identity = 81/254 (31.89%), Postives = 139/254 (54.72%), Query Frame = 1

Query:  202 CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLES----------IANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            C  +H A + G ++VVK+LI+ K N++        P+H     GN+E+++LLI  R ++++           A+     +  KL  ID  N  ++ T +     P+H A   G+  +VKL+IDN  N+ T   + W P+H A   G +D++KLL++N    +T       P+HYA + G++E+V++L++N  N ++   E   P+HYA ++G +D+VK LI N+ N++    +G TPL  A  N N   V +++
Sbjct:   99 CTPLHKAAENGHLDVVKLLIDNKANVDTAQSEGWTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLL-ID--NRANVDTTQNEGCTPLHYASQNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLI 349

HSP 3 Score: 153.295 bits (386), Expect = 1.853e-36
Identity = 83/298 (27.85%), Postives = 152/298 (51.01%), Query Frame = 1

Query:  202 CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN---IPTDENFEKL------FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPER 1068
            C  +H A + G +E+VK+LI  + N++        P+H +   G++++++LLI  + ++++  N    P    F+        F ID  N  ++ TM T  +   HI    G   +VKL+IDN  N+ T D + W P+H A   GH++++K L++N    +T++   +   H A K G +E+V++L++N  N ++ N E   P+HYA ++GH+++VK LI N  N++ ++  G T   +  +N     V +++          +E       A R G     ++ +   A ++TK  R
Sbjct:  449 CTPLHYASRNGNLELVKLLIENRANVDTAQNEGWTPLHYSSQNGHLKVVKLLIENKANVDTTQNEGWTPLHYAFQNGHLEVVKFLID--NGANVDTMNTRGSTSFHIVSQNGRLVLVKLLIDNRANVDTTDNEGWTPLHYASQNGHLEVVKFLIDNGANFDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNRANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNTR 744

HSP 4 Score: 150.984 bits (380), Expect = 1.169e-35
Identity = 80/277 (28.88%), Postives = 148/277 (53.43%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++GN +E+ K L     + D   +     +H A + G ++VVK+LI+ + N++        P+H     GN+E+++LLI  R ++++         +  +      +  +  +N  ++ T +     P+H A   G+  +VKL+IDN  N+ T   + W P+H A   G +D++KLL++N    +T       P+HYA + G++E+V++L++N  N ++   E   P+HYA ++G +D+VK LI N+ N++    +G TPL  A  N N   V +++
Sbjct:  140 RNGN-LELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASQNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLI 415

HSP 5 Score: 148.288 bits (373), Expect = 1.032e-34
Identity = 73/248 (29.44%), Postives = 138/248 (55.65%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A  +G +E+VK+LI+   NI+ +      P+H     GN+E+++LLI  R ++++  N         +      +  +  +N  ++ T +     P+H A   GH ++VKL+IDN  N+ T   + W P+H A   G+++++KLL++N    +T       P+HYA + G +++V++L++N  N ++   E   P+HYA ++G++++VK LI N+ N++    +G TPL  A +N     V +++
Sbjct:    3 LHTAAGKGNIEMVKLLIDHNANIDTKDDEGCTPLHYASRNGNLEMVKLLIDNRANVDTTQNEGWTPLHYASQNGHIDVVKLLIDNRANVDTTQNEGCTPLHKAAENGHLDVVKLLIDNKANVDTAQSEGWTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASQNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLI 250

HSP 6 Score: 145.206 bits (365), Expect = 1.156e-33
Identity = 74/255 (29.02%), Postives = 128/255 (50.20%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALEN 903
            +EV K L     + D        + H+A K G +EVVK+LI+   N++        P+H     G++E+++LLI                          +N  ++ T     +   HI    G   +VKL+IDN  N+ T D + W P+H A   GH++++KLL++N    +T++   +   H A K G +E+V++L++N  N ++ N E   P+HYA ++GH+++VK LI N  N++ ++  G T   +  +N
Sbjct:  593 LEVVKFLIDNGANFDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLI--------------------------DNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNRANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQN 821

HSP 7 Score: 144.436 bits (363), Expect = 1.622e-33
Identity = 86/323 (26.63%), Postives = 159/323 (49.23%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDID-SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPERNICKICY 1089
            ++GN +E+ K L     + D   +     +H A + G ++VVK+LI+ + N++        P+H     GN+E+++LLI  R      AN+ T + +E    +  +  + ++ T +     P+H A   G+  +VKL+I+N  N+ T   + W P+H +   GH+ ++KLL+EN    +T       P+HYA + GH+E+V+ L++N  N ++ N       H   ++G + +VK LI N+ N++  D +G TPL  A +N +   V  ++        K +    +F  A + G     ++ +   A ++T        + Y
Sbjct:  338 RNGN-LELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNR------ANVDTAQ-YEGWTPLHYASRNANVDTTQNEGCTPLHYASRNGNLELVKLLIENRANVDTAQNEGWTPLHYSSQNGHLKVVKLLIENKANVDTTQNEGWTPLHYAFQNGHLEVVKFLIDNGANVDTMNTRGSTSFHIVSQNGRLVLVKLLIDNRANVDTTDNEGWTPLHYASQNGHLEVVKFLIDNGANFDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHY 652

HSP 8 Score: 143.28 bits (360), Expect = 4.683e-33
Identity = 72/244 (29.51%), Postives = 134/244 (54.92%), Query Frame = 1

Query:  202 CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN--------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            C  +H A + G +E+VK+LI+ + N++        P+H     G +++++LLI  R ++++  N           + N E L  +  +N  ++ T +     P+H A   G  ++VKL+IDN  N+ T   +   P+H A   G+++++KLL++N    +T       P+HYA + G +++V++L++N  N ++   E   P+HYA ++G++++VK LI N+ N++    +G TPL  A  N N
Sbjct:  198 CTPLHYASQNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLE-LVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNAN 440

HSP 9 Score: 138.272 bits (347), Expect = 2.217e-31
Identity = 78/297 (26.26%), Postives = 148/297 (49.83%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVD--------------------ILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++GN +E+ K L     + D   +     +H A + G ++VVK+LI+ + N++        P+H     GN+E+++LLI  R ++++         +  +      +  +  +N  ++ T +     P+H A   G+  +VKL+IDN  N+ T   + W P+H A    +VD                    ++KLL+EN    +T       P+HY+ + GH+++V++L+EN  N ++   E   P+HYA ++GH+++VKFLI N  N++  +  G T   +  +N   + V +++
Sbjct:  272 RNGN-LELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNANVDTTQNEGCTPLHYASRNGNLELVKLLIENRANVDTAQNEGWTPLHYSSQNGHLKVVKLLIENKANVDTTQNEGWTPLHYAFQNGHLEVVKFLIDNGANVDTMNTRGSTSFHIVSQNGRLVLVKLLI 567

HSP 10 Score: 136.346 bits (342), Expect = 1.026e-30
Identity = 68/217 (31.34%), Postives = 122/217 (56.22%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLES--------IANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+H     GNIE+++LLI +  ++++        +     + N E +  +  +N  ++ T +     P+H A   GH ++VKL+IDN  N+ T   +   P+H A   GH+D++KLL++N    +T       P+HYA + G++E+V++L++N  N ++   E   P+HYA ++G +D+VK LI N+ N++    +G TPL  A +N N   V +++
Sbjct:    2 PLHTAAGKGNIEMVKLLIDHNANIDTKDDEGCTPLHYASRNGNLE-MVKLLIDNRANVDTTQNEGWTPLHYASQNGHIDVVKLLIDNRANVDTTQNEGCTPLHKAAENGHLDVVKLLIDNKANVDTAQSEGWTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASQNGNLELVKLLI 217

HSP 11 Score: 135.961 bits (341), Expect = 1.158e-30
Identity = 83/300 (27.67%), Postives = 151/300 (50.33%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLES----------IANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVD--------------------IVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++GN +E+ K L     + D   +     +H A + G ++VVK+LI+ + N++        P+H     GN+E+++LLI  R ++++           A+     +  KL  ID  N  ++ T +     P+H A   G+  +VKL+IDN  N+ T   + W P+H A   G +D++KLL++N    +T       P+HYA + G++E+V++L++N  N ++   E   P+HYA ++ +VD                    +VK LI N+ N++    +G TPL  + +N +   V +++
Sbjct:  206 QNGN-LELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNGQLDVVKLL-ID--NRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASQNGQLDVVKLLIDNRANVDTTQNEGCTPLHYASRNGNLELVKLLIDNRANVDTAQYEGWTPLHYASRNANVDTTQNEGCTPLHYASRNGNLELVKLLIENRANVDTAQNEGWTPLHYSSQNGHLKVVKLLI 501

HSP 12 Score: 122.479 bits (306), Expect = 4.999e-26
Identity = 68/249 (27.31%), Postives = 126/249 (50.60%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLI 834
            F    K+G  +EV K L     + D         +H A + G +EVVK+LI+   N++ +        HI    G +E+++LLI  R ++++  N         +     ++  +  +N  ++ T  T  +   HIA   G   +VKL+IDN  N+ T + + W P+H A   GH++++KLL++N    +T++   +   H   + G +E+V++L++N  N ++   E+   +H A  +GH+++VK  I
Sbjct:  617 FHIASKNGR-LEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNRANVDTTDNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNGANVDTTYNERWTLLHDASLNGHLEVVKLSI 864

HSP 13 Score: 85.8853 bits (211), Expect = 5.251e-14
Identity = 55/213 (25.82%), Postives = 100/213 (46.95%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-DENFEKLFDIDS------------ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVE 738
            +EV K L     + D        + H+  + G +EVVK+LI+ + N++        P+H     G++E+++LLI      ++ AN+ T +      F I S            +N  ++ T       P+H A   GH  +VKL+IDN  N+ T +       H+    G ++++KLL++N    +T    +   +H A   GH+E+V++ ++
Sbjct:  659 LEVVKLLIDNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNRANVDTTDNEGWTPLHYASRNGHLEVVKLLI------DNGANVDTKNTRGSTSFHIASKNGRLEVVKLLIDNGANVDTTNNEGWTPLHYASRNGHLEVVKLLIDNGANVDTKNARGSTSFHIVSQNGRLEVVKLLIDNGANVDTTYNERWTLLHDASLNGHLEVVKLSID 865

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Match: A0A182GGY8 (ANK_REP_REGION domain-containing protein OS=Aedes albopictus OX=7160 GN=RP20_CCG009719 PE=4 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 7.727e-36
Identity = 79/250 (31.60%), Postives = 141/250 (56.40%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H++C+ G  EVV+ILI +K NIE     N  P+H+ C  G+ E++ +LI    ++E++        +I +    EK+ +I      +I  +      P+H+AC  GH  +V+++I    N++   +DNW P+H AC  GH +++++L++     +   + K  P+H AC+ GH E+V IL+    N ++   +K  P+H AC++GH ++V+ L+  K N+E  + D  TPL LA E  ++  V +++ E
Sbjct: 1469 LHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGE 1718

HSP 2 Score: 143.28 bits (360), Expect = 6.011e-33
Identity = 76/250 (30.40%), Postives = 140/250 (56.00%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIP-TDENF------EKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+AC+ G  EVV+ILI +K NI+        P+H+ C  G+ E++ +LI  + ++E++  +  T  +F      +++ +I      +I  +      P+H++C  GH  +V+++I    N++  ++DNW P+H+AC  GH +++++L+      E  ++Y   P+H A   GH ++V IL+    N E+   E   P+H AC++GH ++V+ LI  K N+E    D  TPL  A +N +   V++++ E
Sbjct: 1370 LHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIREKVNIEALNQDNWTPLHLSCRHGHKEVVEILIREKVNIEALNQDNWTPLHLACQDGHKEVVEILIREEANIEALNQYNYTPLHIASWNGHEKVVEILIREKANIEALGQENWTPLHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKE 1619

HSP 3 Score: 135.576 bits (340), Expect = 2.163e-30
Identity = 75/261 (28.74%), Postives = 141/261 (54.02%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI-------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +D N +T    +H AC  G  EVV+ILI  K NI+        P+H  C  G  E++ +LI  + ++E++        ++      +++ +I  + + +I  +   +  P+H+AC +GH   V+++I    N+   D++ + P+H AC  GH +++++L++     +   + K  P+H AC+ GH E+V IL+    N ++   +K  P+H AC++GH ++V+ LI  K N+E  +    TPL  A  N ++  V++++ E
Sbjct: 1197 ADTNEYT---PLHWACISGVKEVVEILIGGKANIDALAKNKSTPLHFACQNGRKEVVEILIREKANIEALNQHNWTPLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILIRGKANIEALNQVNWTPLHFACHNGHKEVVEILIRE 1454

HSP 4 Score: 134.806 bits (338), Expect = 4.952e-30
Identity = 79/292 (27.05%), Postives = 148/292 (50.68%), Query Frame = 1

Query:  103 GVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFE-------------KLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
              F+  V+ G+   V+  LK++F    F        +H+A   G +E VK LIN   N+    +     +HI+   G+  I+ LL      L++ AN+   +  E             ++ +I      +I  +   ++ P+H AC  G   +V+++I    N++  ++ NW P+H+AC  GH +++++L++ N   +   ++K  P+H AC  GH E V+IL+    N ++ +  K  P+H AC++GH ++V+ L+  K N++       TPL LA +N ++  V++++ E
Sbjct: 1104 SAFQTAVQYGH-SSVQDMLKRKFPEHAFTKDIDGPLMHIAAGDGIIEEVKRLINNGANVNAPSVAGYTALHISASSGHRPIVELL------LDNGANVNAADTNEYTPLHWACISGVKEVVEILIGGKANIDALAKNKSTPLHFACQNGRKEVVEILIREKANIEALNQHNWTPLHLACQNGHKEVVEILIKENANIDALTEHKYTPLHLACARGHKEAVQILIGEKANIDALDENKFTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGE 1388

HSP 5 Score: 128.642 bits (322), Expect = 4.398e-28
Identity = 62/214 (28.97%), Postives = 121/214 (56.54%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            +H+AC+ G  EVV+ILI  K NIE     N  P+H  C  G+ E++ +L+  + +++++A       ++      +++ +I      +I  +   ++ P+H+AC  GH  +V++++    N++  ++DNW P+H+AC  GH +++K+L+      +   + K  P+H AC+ GH E+V I +  N N  + + EK  P++ A ++GH ++ K +
Sbjct: 1568 LHLACRNGHKEVVEILIRGKANIEALTQDNWTPLHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGEKANIDALTQKKNTPLHLACQRGHKEVVEIFLRKNANIAALDDEKCTPLNLASQNGHTEVEKIM 1781

HSP 6 Score: 93.9745 bits (232), Expect = 1.439e-16
Identity = 49/183 (26.78%), Postives = 95/183 (51.91%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVE 738
            +H AC+ G  EVV+IL+ +K NI+        P+H+ C  G+ E++ +LI  + +++++        ++      +++ +I      +I  +      P+H+AC KGH  +VK++I    N+    +    P+H+AC  GH +++++ L  N      D  K  P++ A + GH E+ +I+ E
Sbjct: 1601 LHKACQNGHAEVVEILVKEKANIDALAEKKFTPLHLACQNGHKEVVEILIGEKANIDALTEKKSTPLHLACQNGHKEVVEILVGEKANIEALNQDNWTPLHLACEKGHKEVVKILIGEKANIDALTQKKNTPLHLACQRGHKEVVEIFLRKNANIAALDDEKCTPLNLASQNGHTEVEKIMKE 1783

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Match: ank1b (ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GENE-091113-6])

HSP 1 Score: 114.005 bits (284), Expect = 1.229e-26
Identity = 69/253 (27.27%), Postives = 120/253 (47.43%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   + K+L++K        +    P+HI C   ++  + LL+ +   LE++          A      N  K   +    S + S +K V+T P+H+A   GHC + + ++ N   +    KD+  P+H A   GH +++KLLLE+    ++       P+H A + GH    RIL++ N        +   P+H ACK G VD+ + L+    N      +G TPL +A+ +NN   V +++++
Sbjct:  317 LHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVAAFMGHLNIVKSL-LQRGASPNASNVK-VET-PLHMAARAGHCEVAQFLLQNLAQVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPDSATTAGHTPLHIAAREGHAHTTRILLDGNAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSK 566

HSP 2 Score: 98.5969 bits (244), Expect = 1.485e-21
Identity = 57/243 (23.46%), Postives = 109/243 (44.86%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H+A + G  EV + L+     ++ +   +  P+H    +G+ E+++LL+ ++ + +S                            T    P+HIA  +GH +  ++++D +       K  + P+HVAC YG VD+ +LLLE         K    P+H A    ++++V++LV    +  S       P+H A K   +++   L+    N   E + G TPL LA +      V +++++
Sbjct:  416 LHMAARAGHCEVAQFLLQNLAQVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPDSAT--------------------------TAGHTPLHIAAREGHAHTTRILLDGNAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTPLHIAAKQNQLEVASSLLQCGANANSESLQGITPLHLAAQEGRPDMVALLISK 632

HSP 3 Score: 93.9745 bits (232), Expect = 4.989e-20
Identity = 67/293 (22.87%), Postives = 136/293 (46.42%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN--IPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH   +  T  +    A+H+A   G  +VV  L++   N+  +      P+++     ++E+++ L      LE+ AN  +PT++ F  L     +  E++        T   V+   +HIA          +++ ND N     K  + P+H+A  Y ++ + +LLL          K    P+H A + G+V +VR+L++     +++  ++  P+H A ++GHV +++ L+     ++ +  +G +P+ +A + ++  CV  +L
Sbjct:   19 NGLNGLHLASKEGHV-----KMVLELLHHGIDLETTTKKGNTALHIAALAGQEKVVAELVHYGANVNAQSQKGFSPLYMAAQENHLEVVKFL------LENGANQSLPTEDGFTPLAVALQQGHENVVALLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIAARRGNVIMVRLLLDRGAQIDARTKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLL 300

HSP 4 Score: 93.9745 bits (232), Expect = 5.711e-20
Identity = 60/251 (23.90%), Postives = 111/251 (44.22%), Query Frame = 1

Query:  154 RLKKEFLHSDFNP----FTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            R     L +D NP     T    +H+A     + V ++L+N+  N+       I P+HI    GN+ ++RLL+                  ++   ID+   + ++        P+H A   GH  ++++++D    +Q   K+   PIH+A    H+D ++ LL+ N   +        P+H A   GH  + ++L++      ++ +    P+H ACK  H+  +  L+ +  +LE     G TPL +A
Sbjct:  162 RTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKNGITPLHIAARRGNVIMVRLLL------------------DRGAQIDARTKDELT--------PLHCAARNGHVRVIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLLKHSASLEAVTESGLTPLHVA 386

HSP 5 Score: 91.6633 bits (226), Expect = 2.912e-19
Identity = 62/242 (25.62%), Postives = 108/242 (44.63%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A +        +L+    N +        P+HI     N+ + +LL      L   AN+    NF               T K   T P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV ++++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   +D++L
Sbjct:  151 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLL------LNRGANV----NF---------------TPKNGIT-PLHIAARRGNVIMVRLLLDRGAQIDARTKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKANARALNGFTPLHIACKKNHMRSMDLLL 366

HSP 6 Score: 85.8853 bits (211), Expect = 2.392e-17
Identity = 65/277 (23.47%), Postives = 124/277 (44.77%), Query Frame = 1

Query:  115 KVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDEN----FEKLFDIDSE-NSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWK-----PIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +++  GN  + K   K       F P      +HVACK G V+V ++L+ +  N        + P+H+     N+++++LL++      S A       +I   +N       L    +  NSES+  +      P+H+A  +G  ++V L+I    N+   +K   +     P+H+    GHV I  +L++   +  +  +     +H AC  G++++V+ L++   +   +      P+H A + GH DIV  L+ +         +G +PL +A
Sbjct:  495 RILLDGNAQQTKMTKK------GFTP------LHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYTPLHIAAKQNQLEVASSLLQCGANANSESLQGIT-----PLHLAAQEGRPDMVALLISKQGNVNLGNKVRTQLTALTPLHLVAQEGHVGIADMLVKQGASVYSASRMGYTALHVACHYGNIKMVKFLLQQQAHVNCKTRVGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIA 754

HSP 7 Score: 82.4185 bits (202), Expect = 2.655e-16
Identity = 63/278 (22.66%), Postives = 118/278 (42.45%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTR-----PIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  L    NP +   A    +H+A ++G     +IL++      +       P+H+ C  G +++  LL+        A +  L  +       N + +  + S+     ST +   T P+HIA  +    +   ++    N  +       P+H+A   G  D++ LL+         +K +T+     P+H   + GHV I  +LV+   +  S +      +H AC  G++ +VKFL+  + ++  +   G TPL  A +  +   V ++L
Sbjct:  458 KELVKLLLEHKANPDSATTAGHTPLHIAAREGHAHTTRILLDGNAQQTKMTKKGFTPLHVACKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVKLLVSKGGSPHSTARNGYT-PLHIAAKQNQLEVASSLLQCGANANSESLQGITPLHLAAQEGRPDMVALLISKQGNVNLGNKVRTQLTALTPLHLVAQEGHVGIADMLVKQGASVYSASRMGYTALHVACHYGNIKMVKFLLQQQAHVNCKTRVGYTPLHQAAQQGHTDIVTLLL 734

HSP 8 Score: 77.7962 bits (190), Expect = 8.016e-15
Identity = 56/253 (22.13%), Postives = 110/253 (43.48%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V + +V  G       R          N +T    +H+A KQ  +EV   L+    N   E +  I P+H+    G  +++ LLI+ + ++ ++ N                    + T  T  T P+H+   +GH  I  +++    ++ +  +  +  +HVAC YG++ ++K LL+       + +    P+H A + GH +IV +L+++             P+  A + G++ ++  L
Sbjct:  548 LHVAVHHNNLDVVKLLVSKGGSPHSTAR----------NGYT---PLHIAAKQNQLEVASSLLQCGANANSESLQGITPLHLAAQEGRPDMVALLISKQGNV-NLGN-------------------KVRTQLTALT-PLHLVAQEGHVGIADMLVKQGASVYSASRMGYTALHVACHYGNIKMVKFLLQQQAHVNCKTRVGYTPLHQAAQQGHTDIVTLLLKHGALPNEITTNGTSPLGIAKRLGYISVIDVL 766

HSP 9 Score: 72.4034 bits (176), Expect = 4.850e-13
Identity = 61/262 (23.28%), Postives = 118/262 (45.04%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
             +H+A K+G V++V  L++   ++E         +HI  L G  +++  L+ Y  ++ + +        +   EN  ++     EN  + S        P+ +A  +GH N+V L+I    N  T  K     +H+A          +LL+N+   +   K    P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++    D  TPL  A  N +   ++++L +   I+A+ K
Sbjct:   23 GLHLASKEGHVKMVLELLHHGIDLETTTKKGNTALHIAALAGQEKVVAELVHYGANVNAQSQKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLSVAQLLLNRGANVNFTPKN--GITPLHIAARRGNVIMVRLLLDRGAQIDARTKDELTPLHCAARNGHVRVIEILLDQGAPIQAKTK 278

HSP 10 Score: 69.3218 bits (168), Expect = 4.098e-12
Identity = 39/133 (29.32%), Postives = 68/133 (51.13%), Query Frame = 1

Query:  535 IDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            I N   + T +++    +H+A   GHV ++  LL +    ET  K     +H A   G  ++V  LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  +   DG TPL +AL+  +E  V +++
Sbjct:    7 IKNGIAINTANQNGLNGLHLASKEGHVKMVLELLHHGIDLETTTKKGNTALHIAALAGQEKVVAELVHYGANVNAQSQKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLI 139

HSP 11 Score: 57.7658 bits (138), Expect = 1.934e-8
Identity = 31/133 (23.31%), Postives = 64/133 (48.12%), Query Frame = 1

Query:  439 ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH 837
            +N  +I+T        +H+A  +GH  +V  ++ +  +L+T  K     +H+A + G   ++  L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI+
Sbjct:    8 KNGIAINTANQNGLNGLHLASKEGHVKMVLELLHHGIDLETTTKKGNTALHIAALAGQEKVVAELVHYGANVNAQSQKGFSPLYMAAQENHLEVVKFLLENGANQSLPTEDGFTPLAVALQQGHENVVALLIN 140

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Match: ank1a (ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GENE-041010-44])

HSP 1 Score: 112.464 bits (280), Expect = 4.216e-26
Identity = 68/253 (26.88%), Postives = 123/253 (48.62%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G   + K+L++K        +    P+HI C   ++ ++ LL+ +   LE++          A+     N  K+  +    S + S +K V+T P+H+A   GHC + + ++ N   +    KD+   +H A   GH +++KLLLE+     +       P+H A + GH + VRIL++ N        +   P+H A K G VD+ + L+    N      +G TPL +A+ +NN   V++++++
Sbjct:  314 LHVAAHCGHHRMAKVLLDKGAKPNTRALNGFTPLHIACKKNHLRVMDLLLKHSASLEAVTESGLTPLHVASFMGHLNIVKIL-LQKGASPNASNVK-VET-PLHMASRAGHCEVAEFLLQNAAPVDAKAKDDQTSLHCAARMGHKELVKLLLEHKANPNSTTTAGHTPLHIAAREGHTQTVRILLDMNAQQTKMTKKGFTPLHVAAKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSK 563

HSP 2 Score: 112.464 bits (280), Expect = 4.793e-26
Identity = 66/289 (22.84%), Postives = 141/289 (48.79%), Query Frame = 1

Query:  124 KSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
            + GNV+ V+  L +     D     +   +H A + G V +++IL+++   I+ +    + P+H+     +++ +R L+ Y  +++ I        ++       ++  +  +     +T       P+HIAC K H  ++ L++ +  +L+   +    P+HVA   GH++I+K+LL+   +    +     P+H A + GH E+   L++N    +++  + +  +H A + GH ++VK L+ +K N       G TPL +A    +   V  IL ++ A++ K+++
Sbjct:  220 RRGNVIMVRLLLDRG-ATIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNTRALNGFTPLHIACKKNHLRVMDLLLKHSASLEAVTESGLTPLHVASFMGHLNIVKILLQKGASPNASNVKVETPLHMASRAGHCEVAEFLLQNAAPVDAKAKDDQTSLHCAARMGHKELVKLLLEHKANPNSTTTAGHTPLHIAAREGHTQTV-RILLDMNAQQTKMTK 506

HSP 3 Score: 97.4413 bits (241), Expect = 3.682e-21
Identity = 70/296 (23.65%), Postives = 128/296 (43.24%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI-------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            + +  K N+L V + ++K    +E           S   P      +HVA   G + +VKIL+ K  +     +    P+H+    G+ E+   L+       A   D ++  +       ++L  +  E+  + ++  T    P+HIA  +GH   V++++D +       K  + P+HVA  YG VD+ +LLLE         K    P+H A    ++++V +LV    +  S       P+H A K   V++   L+    +   E + G TPL LA +      V +++++
Sbjct:  347 LHIACKKNHLRVMDLLLKHSASLEA-------VTESGLTP------LHVASFMGHLNIVKILLQKGASPNASNVKVETPLHMASRAGHCEVAEFLLQNAAPVDAKAKDDQTSLHCAARMGHKELVKLLLEHKANPNSTTTAGHTPLHIAAREGHTQTVRILLDMNAQQTKMTKKGFTPLHVAAKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTPLHIASKQNQVEVASSLLQYGASANAESLQGVTPLHLAAQEGRADMVSLLISK 629

HSP 4 Score: 92.8189 bits (229), Expect = 1.095e-19
Identity = 58/240 (24.17%), Postives = 112/240 (46.67%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDI-----DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA K G V+V ++L+ +  N        + P+H+     N++++ LL++      S A       +I + +N  ++         S N+ES+  +      P+H+A  +G  ++V L+I    N+   +K    P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   N   +      P+H A + GH DIV  L+ +         +G + L +A
Sbjct:  512 LHVAAKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTPLHIASKQNQVEVASSLLQYGASANAESLQGVT-----PLHLAAQEGRADMVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNGKTRAGYTPLHQAAQQGHTDIVTLLLKHGAQPNEITTNGTSALAIA 746

HSP 5 Score: 92.0485 bits (227), Expect = 2.312e-19
Identity = 72/302 (23.84%), Postives = 137/302 (45.36%), Query Frame = 1

Query:  106 VFEKVVKSGNV------MEVKKRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI---AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            V E   K GN       +  ++++  E ++   N   Q Q     +++A ++  +EVVK L+    N  Q +   +KP  ++  + N     L +   A    L+++ +  T   F  L    + + E+++  + +  R             P+HIA  +G+  +V+L++D    +    KD   P+H A   GHV I+++LL+     + + K    PIH A +  H++ VR L++ N   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   +D++L
Sbjct:   68 VLETTTKKGNTALHIAALAGQEQVVTELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN--QSIPTEVKPSAVS--LANSYSFPLYLSTNASHITLKNVCSFITATGFTPLHI--AAHYENLNVAQLLLNRGANVNFTPKNGITPLHIASRRGNVIMVRLLLDRGATIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTKNGLSPIHMAAQGDHMDCVRQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNTRALNGFTPLHIACKKNHLRVMDLLL 363

HSP 6 Score: 91.2781 bits (225), Expect = 3.929e-19
Identity = 53/244 (21.72%), Postives = 113/244 (46.31%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            ++H A + G  E+VK+L+  K N          P+HI    G+ + +R+L+                      D++++ ++    M      P+H+A   G  ++ +L+++   N     K+   P+HVA  + ++D++ LL+    +  +  +    P+H A K   VE+   L++   +  +++++   P+H A + G  D+V  LI  + N+ + +  G TPL L  +  +    D+++ +
Sbjct:  445 SLHCAARMGHKELVKLLLEHKANPNSTTTAGHTPLHIAAREGHTQTVRILL----------------------DMNAQQTK----MTKKGFTPLHVAAKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTPLHIASKQNQVEVASSLLQYGASANAESLQGVTPLHLAAQEGRADMVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQ 662

HSP 7 Score: 85.1149 bits (209), Expect = 4.247e-17
Identity = 62/273 (22.71%), Postives = 114/273 (41.76%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            K L K  L    NP +   A    +H+A ++G  + V+IL++      +       P+H+    G +++  LL+        A +  L  +       N + +  + S+     S  +   T P+HIA  +    +   ++    +          P+H+A   G  D++ LL+         +K    P+H   + GHV I  ILV+   +  +       P+H AC  G++ +VKFL+  + N+  +   G TPL  A +  +   V ++L
Sbjct:  455 KELVKLLLEHKANPNSTTTAGHTPLHIAAREGHTQTVRILLDMNAQQTKMTKKGFTPLHVAAKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYT-PLHIASKQNQVEVASSLLQYGASANAESLQGVTPLHLAAQEGRADMVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNGKTRAGYTPLHQAAQQGHTDIVTLLL 726

HSP 8 Score: 76.2554 bits (186), Expect = 2.871e-14
Identity = 53/253 (20.95%), Postives = 105/253 (41.50%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            + V   +NNL V   +V  G       R          N +T    +H+A KQ  VEV   L+    +   E +  + P+H+    G  +++ LLI+                  K  +++  N   ++        P+H+   +GH  I  +++    ++    +  + P+HVAC YG++ ++K LL+       + +    P+H A + GH +IV +L+++              +  A + G++ ++  L
Sbjct:  545 LHVAVHHNNLDVVNLLVSKGGSPHSAAR----------NGYT---PLHIASKQNQVEVASSLLQYGASANAESLQGVTPLHLAAQEGRADMVSLLIS------------------KQANVNLGNKSGLT--------PLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNGKTRAGYTPLHQAAQQGHTDIVTLLLKHGAQPNEITTNGTSALAIAKRLGYISVIDVL 758

HSP 9 Score: 60.077 bits (144), Expect = 3.689e-9
Identity = 62/295 (21.02%), Postives = 125/295 (42.37%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYG-----HVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN--NCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE---IEARKK 957
            F +  +SGN+ +    +K      D N   Q     +H+A K+G V++V  L++    +E         +HI  L G  +++  L+ Y  ++    N  + + F                       P+++A  + H  +VK +++N  N     +     + +A  Y        +   + L+N C+  T   +   P+H A    ++ + ++L+    N NF  +N     P+H A + G+V +V+ L+     ++ +  D  TPL  A  N +   ++++L +   I+A+ K
Sbjct:   14 FLRAARSGNLDKALDHIKNGI---DINTANQNGLNGLHLASKEGHVKMVLELLHNGVVLETTTKKGNTALHIAALAGQEQVVTELVNYGANV----NAQSQKGFT----------------------PLYMAAQENHLEVVKFLLENGANQSIPTEVKPSAVSLANSYSFPLYLSTNASHITLKNVCSFITATGFT--PLHIAAHYENLNVAQLLLNRGANVNFTPKN--GITPLHIASRRGNVIMVRLLLDRGATIDAKTKDELTPLHCAARNGHVRIIEILLDQGAPIQAKTK 275

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Match: ENSAMXT00000037173.1 (pep primary_assembly:Astyanax_mexicanus-2.0:16:21074007:21119253:-1 gene:ENSAMXG00000017269.2 transcript:ENSAMXT00000037173.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.768 bits (273), Expect = 7.841e-26
Identity = 70/313 (22.36%), Postives = 138/313 (44.09%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN-------IPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            F +  ++GN+ +V + LK      D     Q    A+H+A K+G +++V+ L+ +  +++         +HI  L G  E++++L+    D+ + +        + + EN   +     EN  + ST       P+ IA  +GH  +V ++++ND                              N     K  + P+H+A  YG+V++  LLL      +   +    P+H A K G+  +VR+L++     +++  +   P+H A +SGH   V+ L+     +     +G +PL +A + ++  CV  +L
Sbjct:   19 FLRAARAGNIDKVLEYLKGGV---DIGTSNQNGLNALHLAAKEGHMDLVQELLERGSSVDSATKKGNTALHIASLAGQAEVVKILVKQGADINAQSQNGFTPLYMASQENHLDVVRYLLENGGNQSTATEDGFTPLAIALQQGHNQVVSILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPILARTKNGLSPLHMAAQGDHVECVKHLL 328

HSP 2 Score: 95.5153 bits (236), Expect = 5.440e-21
Identity = 62/267 (23.22%), Postives = 114/267 (42.70%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
             L +D     +  A+H+A ++   +   +L+    N + +      P+HI    GN+ +  LL+                N     D  + N  +          P+H+A  +G+ N+V+L++D    +    +D   P+H A   GH   ++LLLE         K    P+H A +  HVE V+ L+++    +   ++    +H A   GH  + K L+  + N     ++G TPL +A +  N + V  +L +  A  + I+E
Sbjct:  166 LLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLL----------------NRGAAVDFTARNGIT----------PLHVASKRGNTNMVRLLLDRGSQIDAKTRDGLTPLHCAARSGHDTAVELLLERGAPILARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACK-KNRVKVMELLVKYGASIQAITE 405

HSP 3 Score: 86.2705 bits (212), Expect = 5.929e-18
Identity = 54/246 (21.95%), Postives = 109/246 (44.31%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
             L +D N   Q ++    +H+A   G V V  +L+N+   ++      I P+H+    GN  ++RLL+                  ++   ID++  + ++        P+H A   GH   V+L+++    +    K+   P+H+A    HV+ +K LL++    +         +H A   GH  + ++L++   N  ++ +    P+H ACK   V +++ L+    +++     G TP+ +A
Sbjct:  195 LLQNDHNADVQSKSGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVRLLL------------------DRGSQIDAKTRDGLT--------PLHCAARSGHDTAVELLLERGAPILARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVA 414

HSP 4 Score: 56.6102 bits (135), Expect = 2.459e-8
Identity = 34/149 (22.82%), Postives = 68/149 (45.64%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTE 657
            +H+A +   VE VK L+  K  ++   +  +  +H+    G+  + +LL+  R +                      N+ +++        P+HIAC K    +++L++    ++Q   +    PIHVA   GH++I+ LLL+N  + +
Sbjct:  312 LHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN---------------------PNARALNGFT-----PLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPD 434

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Match: ENSAMXT00000048191.1 (pep primary_assembly:Astyanax_mexicanus-2.0:15:3100273:3104460:1 gene:ENSAMXG00000036724.1 transcript:ENSAMXT00000048191.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 99.3673 bits (246), Expect = 4.240e-23
Identity = 62/255 (24.31%), Postives = 117/255 (45.88%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNI-EQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENS------------ESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDL-ALENNNEICVDMIL 933
            +H A   G V ++ +LI+   N+  ++ +W + P+H      N   + LL+    D+ +      D+ ++    I + N              S++         +H A   G   +VKL+++   +L  +DK   +PIH A   GH++++KLL+        +DK    P+H A  +GHV++V+ L+ N    +  N      +H AC  G   +   L++   N+   +  G TPL L A+  N  +C+++++
Sbjct:   31 LHAAAWLGDVHIMDLLISAGANVNAKDHVW-LTPLHRAAASRNERAVGLLLRKGADVTA-----RDKFWQTALHIAAANRATRCADTLLPHISSLNIADRTGRAALHHAAQSGCQEMVKLLLNKGASLSASDKKERQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYMGQEAVANELVNRGANVNQPNNRGYTPLHLAAVSTNGALCLELLV 279

HSP 2 Score: 69.3218 bits (168), Expect = 9.325e-13
Identity = 44/183 (24.04%), Postives = 77/183 (42.08%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKY------------KTR---------------------PIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+H A W G  +I+ L+I    N+   D     P+H A    +   + LLL         DK+             TR                      +H+A ++G  E+V++L+    +  + + ++R+PIH+A   GH+++VK L+    +   +D  G TPL  A  + +   V  +L
Sbjct:   30 PLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKFWQTALHIAAANRATRCADTLLPHISSLNIADRTGRAALHHAAQSGCQEMVKLLLNKGASLSASDKKERQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLL 212

HSP 3 Score: 56.9954 bits (136), Expect = 9.858e-9
Identity = 44/195 (22.56%), Postives = 78/195 (40.00%), Query Frame = 1

Query:  196 TQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYAC-KTGHVEIVRILVENNCNFESQNIEKR 777
            T   A+H A + G  E+VK+L+NK  ++        +P+H    +G++E+++LL+                         S+ S+     K   T P+H A   GH ++VK ++ N   +   +      +HVAC  G   +   L+         +     P+H A   T     + +LV N  +   Q  E +
Sbjct:  125 TGRAALHHAAQSGCQEMVKLLLNKGASLSASDKKERQPIHWAAYLGHLEVVKLLV-------------------------SQGSDKSCKDKRGYT-PLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYMGQEAVANELVNRGANVNQPNNRGYTPLHLAAVSTNGALCLELLVNNGADVNMQVWENQ 293

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Match: dapk1 (death-associated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-060526-177])

HSP 1 Score: 101.293 bits (251), Expect = 2.193e-22
Identity = 72/296 (24.32%), Postives = 138/296 (46.62%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-------------------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTV 1038
            AI+ A + G VE +K L  KKC ++ +       +H+    GN+++++    Y C + +  ++   E    L                    D+++ N E  S + T   R        G  +IV+ ++++  ++ + DKD    +H+A     ++++K LL ++C  + +D++   P+H ACK G++ ++ +L     N +  N   R  +H A  +G V++V+ L     N E    DGKT  DLA     E  + ++L +++    K S ++Q      RP  S + R+K+ +
Sbjct:  413 AIYYASRHGHVETLKYLHEKKCPLDVQDKSGETALHVAARYGNVDVVQ----YLCSIHANPDLTDREQETPLHCAAWHGYSPVARALCEAGCDVNARNREGESPLLTASAR--------GFRDIVECLLEHGADMDSTDKDGHIALHLAVRRCQIEVVKCLLSHHCYVDHQDRHGNTPLHIACKDGNLPVISLLSTAKANLDIPNKFGRTALHVAASNGGVEVVRHLCVAGANTEAITNDGKTAEDLATAEQQE-HIAVLLAKLKKDNHKGSYIQQL-----RPTQSPQPRIKLKL 690

HSP 2 Score: 78.1814 bits (191), Expect = 6.411e-15
Identity = 43/160 (26.88%), Postives = 74/160 (46.25%), Query Frame = 1

Query:  418 KLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLAL 897
            ++ D+       I  +       I+ A   GH   +K + +  C L   DK     +HVA  YG+VD+++ L   +   +  D+ +  P+H A   G+  + R L E  C+  ++N E   P+  A   G  DIV+ L+ +  +++  D DG   L LA+
Sbjct:  391 QIIDVLMRKGAEIQALDKSGANAIYYASRHGHVETLKYLHEKKCPLDVQDKSGETALHVAARYGNVDVVQYLCSIHANPDLTDREQETPLHCAAWHGYSPVARALCEAGCDVNARNREGESPLLTASARGFRDIVECLLEHGADMDSTDKDGHIALHLAV 550

HSP 3 Score: 73.1738 bits (178), Expect = 2.827e-13
Identity = 41/154 (26.62%), Postives = 75/154 (48.70%), Query Frame = 1

Query:  424 FDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPL 885
            +DI+  N           T P+ IA   G+  I+ +++     +Q  DK     I+ A  +GHV+ LK L E  C  + +DK     +H A + G+V++V+ L   + N +  + E+  P+H A   G+  + + L    C++   + +G++PL
Sbjct:  368 YDINQPNKHG--------TPPLLIAAGCGNVQIIDVLMRKGAEIQALDKSGANAIYYASRHGHVETLKYLHEKKCPLDVQDKSGETALHVAARYGNVDVVQYLCSIHANPDLTDREQETPLHCAAWHGYSPVARALCEAGCDVNARNREGESPL 513

HSP 4 Score: 63.5438 bits (153), Expect = 2.464e-10
Identity = 33/115 (28.70%), Postives = 59/115 (51.30%), Query Frame = 1

Query:  550 NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            ++   +K    P+ +A   G+V I+ +L+      +  DK     I+YA + GHVE ++ L E  C  + Q+      +H A + G+VD+V++L     N ++ D + +TPL  A
Sbjct:  369 DINQPNKHGTPPLLIAAGCGNVQIIDVLMRKGAEIQALDKSGANAIYYASRHGHVETLKYLHEKKCPLDVQDKSGETALHVAARYGNVDVVQYLCSIHANPDLTDREQETPLHCA 483

HSP 5 Score: 53.9138 bits (128), Expect = 2.564e-7
Identity = 26/82 (31.71%), Postives = 46/82 (56.10%), Query Frame = 1

Query:  664 DKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN 909
            +K+ T P+  A   G+V+I+ +L+      ++ +      I+YA + GHV+ +K+L   KC L+V+D  G+T L +A    N
Sbjct:  374 NKHGTPPLLIAAGCGNVQIIDVLMRKGAEIQALDKSGANAIYYASRHGHVETLKYLHEKKCPLDVQDKSGETALHVAARYGN 455

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.842 bits (268), Expect = 2.635e-25
Identity = 71/317 (22.40%), Postives = 139/317 (43.85%), Query Frame = 1

Query:  109 FEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDC-----------------------------NLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            F +  ++GN+  +   LK      D N   Q    A+H+A K+G V+VV  L+ ++  I+         +HI  L G  +I+R+L+ +  ++    N  +   F  L+    EN   I          ++V T     P+ +A  +GH  +V L++++D                              N     K  + P+H+A  YG++++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +++ L+     +  +  +G +PL +A +  +  CV ++L
Sbjct:   15 FLRAARNGNLERLMDHLKGGM---DINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANI----NAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLL 324

HSP 2 Score: 103.99 bits (258), Expect = 4.078e-24
Identity = 55/259 (21.24%), Postives = 125/259 (48.26%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKIS 966
            +H+A +   +  V++L+ ++  ++   +  + P+H+    G+  + +LL+    +  + A       +I   +N  K+ ++  ++  SI T       PIH+A + GH N+V+L++ N  +    +     P+H+A   G ++++K LL++      + +    P+H A + G  EIV++L++   +  +       P+++A + GH D+   L+ N  ++      G TPL +A +        ++L +  +   K++
Sbjct:  308 LHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVA 566

HSP 3 Score: 103.219 bits (256), Expect = 7.789e-24
Identity = 59/264 (22.35%), Postives = 125/264 (47.35%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ +L+     + +     T      L    +   E ++ ++ +  R             P+H+A   GH  + KL++D          + + P+H+AC    + +++LLL++  +  T  +    PIH A   GH+ +V++L++N  +  + N+    P+H A ++G +++VK L+ +   + V+  + +TPL +A        V ++L
Sbjct:  232 DFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILA----KTKNGLSPLHM--ATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLL 489

HSP 4 Score: 86.6557 bits (213), Expect = 1.728e-18
Identity = 65/309 (21.04%), Postives = 134/309 (43.37%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQC--QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDI---------------------------------LKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N L       K G+V  V + LK+E   ++ +  T+    A+H+A   G  ++V++L+    NI  +      P+++     ++EI++ L+    D  +  ++ T++ F  L     +  E +        T   V+   +HIA  K   N   L++ ++ N     K  + P+H+A  YG++++                                 +KLLL+     +T+ +    P+H A ++GH +++ +L+E +    ++      P+H A +  H+  V+ L+  +  ++   +D  TPL +A
Sbjct:   43 NGLNALHLASKEGHVDVVTELLKRE---AEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLL----DNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVA 344

HSP 5 Score: 78.9518 bits (193), Expect = 5.279e-16
Identity = 58/267 (21.72%), Postives = 118/267 (44.19%), Query Frame = 1

Query:  178 SDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIW--NIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDM--ILTE 939
            +D +P T+     +H+A K G +EV  +L+ K  + + ++     + P+H+     + ++  LL+       S A       +I   +N  ++  +  E     + +      P+H+A  +GH ++V L++    ++    K     +H+A     V++ ++L ++     T  K    P+H A   G++++V  L+ N     ++      P+H A + GH  +V  L+ ++ +      +G T L +A        VD   ILTE
Sbjct:  526 ADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTLSILTE 792

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000093.1 (pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000093.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.457 bits (267), Expect = 3.322e-25
Identity = 68/257 (26.46%), Postives = 117/257 (45.53%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF--------DIDS---ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEA 948
            +H+A + G +EVVK L+     +  +   +  P+HI   +G  EI++LL+    D     N PT      L+        D+ S   EN   IS +      P+HIA   G   +  L+++   +     K+   P+HVA  Y H  +  LLL+   +  +  K    P+H A K   +E+ ++L+E          +   P+H A + GH D+V  L+    ++ +    G T + LA +  +++ V  ILT+ +A
Sbjct:  447 LHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSD----PNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQ-EDKVNVAEILTKHKA 698

HSP 2 Score: 104.375 bits (259), Expect = 3.110e-24
Identity = 54/228 (23.68%), Postives = 102/228 (44.74%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +HVA   G   V K+L+++        +    P+HI C    I+++ LL+                          ++  SI T       PIH+A + GH N+V+L++ N  +    +     P+H+A   G ++++K LL++      + +    P+H A + G  EIV++L++   +  +       P+++A + GH D+   L+ N  ++      G TPL +A
Sbjct:  348 LHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLL--------------------------KHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIA 549

HSP 3 Score: 103.219 bits (256), Expect = 8.320e-24
Identity = 59/251 (23.51%), Postives = 122/251 (48.61%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTR-------------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            DF        +HVA K+G   +VK+L+++   I+ +    + P+H     G+ +++ +L+    D   +A   T      L    +   E ++ ++ +  R             P+H+A   GH  + KL++D          + + P+H+AC    + +++LLL++  +  T  +    PIH A   GH+ +V++L++N  +  + N+    P+H A ++G +++VK L+ +   + V+  + +TPL +A
Sbjct:  239 DFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLL--ERDAPILAK--TKNGLSPLHM--ATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIA 483

HSP 4 Score: 102.449 bits (254), Expect = 1.531e-23
Identity = 71/335 (21.19%), Postives = 144/335 (42.99%), Query Frame = 1

Query:   79 VVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTR----PIHIACWKGHCNIVKLMIDNDCN-------------------------------------LQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            ++ K++    F +  ++GN+  +   LK      D N   Q    A+H+A K+G V+VV  L+ ++  I+         +HI  L G  +I+R+L+ +  ++    N  +   F  L+    EN   I          ++V T     P+ +A  +GH  +V L++++D                                       L    +  + P+H+A  YG++++  LLL      +   +    P+H A K G+  +V++L++     +++  +   P+H A +SGH  +++ L+     +  +  +G +PL +A +  +  CV ++L
Sbjct:    4 LLDKSDAATSFLRAARNGNLERLMDHLKGGM---DINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANI----NAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLL 331

HSP 5 Score: 100.523 bits (249), Expect = 6.863e-23
Identity = 52/241 (21.58%), Postives = 113/241 (46.89%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H+A +   +  V++L+ ++  ++   +  + P+H+    G+  + +LL+              D   E        N+ +++        P+HIAC K    +++L++ +  ++ T  +    PIHVA   GH+++++LLL+N  ++   +     P+H A + G +E+V+ L+++      +  E + P+H A + G  +IV+ L+    +       G TPL  A    +     ++L
Sbjct:  315 LHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLL--------------DRGGEP-------NARALNGFT-----PLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLL 529

HSP 6 Score: 100.138 bits (248), Expect = 9.603e-23
Identity = 50/250 (20.00%), Postives = 114/250 (45.60%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             N FT    +H+ACK+  ++V+++L+    +I       + P+H+   +G++ +++LL+                          +N  S +        P+H+A   G   +VK ++ +   +    +++  P+H+A   G  +I++LLL+            + P+++A + GH ++  +L+EN  +      +   P+H A K G +++   L+    + + +  +G TPL +A   +++    ++L
Sbjct:  375 LNGFTP---LHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLL--------------------------QNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLL 595

HSP 7 Score: 87.8113 bits (216), Expect = 7.496e-19
Identity = 58/249 (23.29%), Postives = 117/249 (46.99%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT--------DENFEKLFDIDSENSESISTMKTVQTR-----PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            N FT    +++A ++  +E+VK L++   N          P+ +    G+ +++ LL+    D +    +P         D N   L      N++  S M   QT      P+HIA   G+ N+  L+++    +    ++   P+HVA   G+ +++KLLL+     +T+ +    P+H A ++GH +++ +L+E +    ++      P+H A +  H+  V+ L+  +  ++   +D  TPL +A
Sbjct:  108 NGFTP---LYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLL--ESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQTTESGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVA 351

HSP 8 Score: 80.8777 bits (198), Expect = 1.336e-16
Identity = 52/248 (20.97%), Postives = 111/248 (44.76%), Query Frame = 1

Query:  178 SDFNPFTQ--CQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            +D +P T+     +H+A K G +EV  +L+ K  + + +    + P+H+     + ++  LL+       S A       +I   +N  ++  +  E     + +      P+H+A  +GH ++V L++    ++    K     +H+A     V++ ++L ++     T  K    P+H A   G++++V  L+ N     ++      P+H A + GH  +V  L+ ++ +      +G T L +A
Sbjct:  533 ADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKGKNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIA 780

HSP 9 Score: 67.3958 bits (163), Expect = 2.881e-12
Identity = 43/187 (22.99%), Postives = 84/187 (44.92%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEV----------EDIDGKTPLDLALENNNEICVDMILTE 939
            N E+L D   +    I+T        +H+A  +GH ++V  ++  +  + T  K     +H+A + G  DI+++L+E       + +    P++ A +  H+EIV+ L++N  N      +   P+  A + GH  +V  L+ +    +V          +D      L L  E+N ++   M+L +
Sbjct:   22 NLERLMD-HLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKMMLNQ 207

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007449.1 (pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007449.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.0561 bits (240), Expect = 8.257e-22
Identity = 52/252 (20.63%), Postives = 113/252 (44.84%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
             N FT    +H+ACK+  + V+++L+    +IE      + P+H++  +GN+ I+ +L+                          +   S +         +H+A   G   +V+ ++ N   +    ++   P+H+A   G ++I++LLL++  + +        P+H A + GH ++  IL+E+  +      +   P+H A K G +++   L+    + +    +G TPL +A   +N+    ++L +
Sbjct:   13 LNGFT---PLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILL--------------------------QGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQ 235

HSP 2 Score: 90.1225 bits (222), Expect = 1.749e-19
Identity = 54/262 (20.61%), Postives = 110/262 (41.98%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEI----EARKKKISEMRQA 981
            A+H+A + G  EVV+ L+     ++ +      P+HI   +G +EI++LL+                  + +   D+  S   +        P+H+A  +GH ++  +++++  +L    K  + P+HVA  YG +++  LLL+   + +   K    P+H A    + ++  +L++   +  +       P+H A K   ++I   L+            G  PL L  +  +     ++L        A K  +S +  A
Sbjct:   84 ALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLL------------------QHMASPDAATSNGYT--------PLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLA 319

HSP 3 Score: 85.8853 bits (211), Expect = 4.100e-18
Identity = 58/273 (21.25%), Postives = 112/273 (41.03%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +E+ + L +     D         +HVA ++G  +V  IL+    ++         P+H+    G +E+  LL+        A +  L  +      +N +    +  + +   +T K   T P+HIA  K    I   +++         +    P+H+    GH D+  LLL          K    P+H A +   V +  ILV++  +  +       P+  AC  G++ +V FL+ +  ++  +  +G TPL  A +  +   V+++L
Sbjct:  127 LEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYT-PLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL 398

HSP 4 Score: 80.4925 bits (197), Expect = 1.930e-16
Identity = 50/237 (21.10%), Postives = 105/237 (44.30%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVED--IDGKTPLDLA 894
            +HVA K G +EV  +L+ +  + +      + P+H+     N ++  LL+       + A       +I   ++  ++     E     + +      P+H+   +GH ++  L++    ++    K    P+H+A     V++ ++L+++        K    P+  AC  G++++V  L+++  +  S+      P+H A + GH  IV  L+  KC     D  ++G T L +A
Sbjct:  184 LHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL--KCGARPNDVTVNGNTALAIA 418

HSP 5 Score: 71.2478 bits (173), Expect = 2.069e-13
Identity = 46/238 (19.33%), Postives = 97/238 (40.76%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            MEV   L + F   D         +HVA      +V  +L+++  +          P+HI      +EI   L+ Y  +  +I        ++   E    +  +       ++        P+H+A  +   N+ ++++ +  ++    K  + P+ VAC YG++ ++  LL++     ++ K    P+H A + GH  IV +L++         +     +  A + G++ +V  L
Sbjct:  193 MEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 430

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007446.1 (pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1 gene:ENSPMAG00000006704.1 transcript:ENSPMAT00000007446.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.2041 bits (230), Expect = 1.906e-20
Identity = 55/229 (24.02%), Postives = 106/229 (46.29%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            A+HVA   G     K+L++K  N     +    P+HI C    I ++ LL+ Y   +E++                   +ES  T       P+H++ + G+ NIV +++    +    +      +H+A   G  ++++ LL N    + + + +  P+H A + G +EIV++L+++  + ++       P+H A + GH D+   L+ +  +L V    G TPL +A
Sbjct:   75 ALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAV-------------------TESGLT-------PMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVA 277

HSP 2 Score: 90.1225 bits (222), Expect = 1.904e-19
Identity = 52/248 (20.97%), Postives = 120/248 (48.39%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +H A + G  +VV+IL+ +   I  +    + P+H+     ++E +++L+ YR  ++ I        ++       +   +  +   + +        P+HIAC K    +++L++    +++   +    P+HV+   G+++I+ +LL+   +    +      +H A + G  E+VR L+ N    +++  E++ P+H A + G ++IV+ L+ +  + +    +G TPL +A    +E    ++L
Sbjct:   10 LHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILL 257

HSP 3 Score: 83.1889 bits (204), Expect = 3.461e-17
Identity = 55/248 (22.18%), Postives = 111/248 (44.76%), Query Frame = 1

Query:  184 FNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI-------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENN 906
             N FT    +H+ACK+  + V+++L+    +IE      + P+H++  +GN+ I+ +L+       A     E+  ++       ++      N   +      +  P+HIA   G   IV+L++ +  +      + + P+HVA   GH D+  +LLE+  +     K    P+H A K G +E+  +L++   + ++       P+H A    +  +   L+    +      +G TPL +A + +
Sbjct:  103 LNGFT---PLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVSAFMGNLNIVLILLQGGASPNATNVRGETALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLLQHMASPDAATSNGYTPLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKD 347

HSP 4 Score: 76.6406 bits (187), Expect = 4.021e-15
Identity = 50/242 (20.66%), Postives = 104/242 (42.98%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            A+H+A + G  EVV+ L+     ++ +      P+HI   +G +EI++LL+                  + +   D+  S   +        P+H+A  +GH ++  +++++  +L    K  + P+HVA  YG +++  LLL+   + +   K    P+H A    + ++  +L++   +  +       P+H A K   ++I   L+            G  PL L  +  +     ++L
Sbjct:  174 ALHMAARAGQTEVVRSLLRNGAQVDAKAREEQTPLHIAARLGKLEIVQLLL------------------QHMASPDAATSNGYT--------PLHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLL 389

HSP 5 Score: 74.3294 bits (181), Expect = 2.041e-14
Identity = 55/249 (22.09%), Postives = 105/249 (42.17%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +HVA ++G  +V  IL+    ++         P+H+    G +E+  LL+        A +  L  +      +N +    +  + +   +T K   T P+HIA  K    I   +++         +    P+H+    GH D+  LLL          K    P+H A +   V +  ILV++  +  +       P+  AC  G++ +V FL+ +  ++  +  +G TPL  A +  +   V+++L
Sbjct:  241 LHVAAREGHEDVTAILLEHGASLAVTTKKGFTPLHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYT-PLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL 488

HSP 6 Score: 71.633 bits (174), Expect = 1.416e-13
Identity = 50/237 (21.10%), Postives = 105/237 (44.30%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVED--IDGKTPLDLA 894
            +HVA K G +EV  +L+ +  + +      + P+H+     N ++  LL+       + A       +I   ++  ++     E     + +      P+H+   +GH ++  L++    ++    K    P+H+A     V++ ++L+++        K    P+  AC  G++++V  L+++  +  S+      P+H A + GH  IV  L+  KC     D  ++G T L +A
Sbjct:  274 LHVASKYGKMEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLL--KCGARPNDVTVNGNTALAIA 508

HSP 7 Score: 62.7734 bits (151), Expect = 9.448e-11
Identity = 46/238 (19.33%), Postives = 97/238 (40.76%), Query Frame = 1

Query:  139 MEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFL 831
            MEV   L + F   D         +HVA      +V  +L+++  +          P+HI      +EI   L+ Y  +  +I        ++   E    +  +       ++        P+H+A  +   N+ ++++ +  ++    K  + P+ VAC YG++ ++  LL++     ++ K    P+H A + GH  IV +L++         +     +  A + G++ +V  L
Sbjct:  283 MEVASLLLQRFASPDAAGKNGLTPLHVASHYDNQKVALLLLDQGASPHATAKNGYTPLHIAAKKDQLEIATTLLEYGAETNAITRQGVAPLHLGAQEGHADVASLLLARYADVNHATKSGLSPLHLAAQEDKVNVAEILVKHGAHVNATTKLGYTPLIVACHYGNIKMVNFLLQHGADVNSKTKNGYTPLHQAAQQGHTHIVNLLLKCGARPNDVTVNGNTALAIARRLGYISVVDTL 520

HSP 8 Score: 62.3882 bits (150), Expect = 1.125e-10
Identity = 33/122 (27.05%), Postives = 59/122 (48.36%), Query Frame = 1

Query:  568 KDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            +D   P+H A   GH  ++++LLE       + K    P+H A +  HVE V++L++     +   ++    +H A   GH    K L+    N  V  ++G TPL +A + N    ++++L
Sbjct:    4 QDGLTPLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLL 125

HSP 9 Score: 61.2326 bits (147), Expect = 2.758e-10
Identity = 29/137 (21.17%), Postives = 65/137 (47.45%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            P+H A   GH  +V+++++    +    K+   P+H+A    HV+ +++L++     +         +H A   GH    ++L++   N   + +    P+H ACK   + +++ L+    ++E     G TP+ ++
Sbjct:    9 PLHCAARSGHEQVVEILLEQGAPILAKTKNGLSPLHMATQGDHVECVQVLMQYRAPVDDITLDYLTALHVAAHCGHYRTAKVLLDKGANPNVRALNGFTPLHIACKKNRIRVMELLLKYGASIEAVTESGLTPMHVS 145

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007954.1 (pep scaffold:Pmarinus_7.0:GL479092:583:36301:1 gene:ENSPMAG00000007165.1 transcript:ENSPMAT00000007954.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 1.423e-19
Identity = 59/273 (21.61%), Postives = 116/273 (42.49%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPT-----------DENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNI-VKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFV 987
            +A+H A   G  EVVK+L++   ++  +      P+H     G++ ++RLL++ + ++                   D    +L D  ++         T     +H A    H  I ++L++++  ++     D   P+H+  ++G     + L++N    +  DK    P+H A + GH  ++  L+ N  +   +      P+H A  SG  D  + L+    +++  D  G+T L  A    N  C++++L+      KK      AFV
Sbjct:   82 RAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAVVSELLDAGADAGHRNERGFTA----LHFAAASTHGAICLELLVNHHADVNAQSYDGKSPLHMTAIHGRFTRSQTLIQNGGEIDCGDKEGNTPLHIAARYGHELLINTLISNGADAARRGSHGMFPLHLAALSGFSDCCRKLLTPGFDVDAVDEFGRTCLHAAAAGGNAECINLLLSSGADLGKKDRYGSIAFV 350

HSP 2 Score: 85.5001 bits (210), Expect = 4.339e-18
Identity = 51/228 (22.37%), Postives = 97/228 (42.54%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDI-VKFLIHNKCNLEVEDIDGKTPLDL 891
            +HVA     ++    LI    N+          +H     GN+E++ LLI+                             +++ M   + R +H A + GH  +VK+++ N  ++   DK  + P+H A   GHV +++LLL         + +    +H AC  G   +V  L++   +   +N      +H+A  S H  I ++ L+++  ++  +  DGK+PL +
Sbjct:   18 LHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHAAFNGNLEMVNLLIS--------------------------KGANVNAMDKRERRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAVVSELLDAGADAGHRNERGFTALHFAAASTHGAICLELLVNHHADVNAQSYDGKSPLHM 219

HSP 3 Score: 73.9442 bits (180), Expect = 2.782e-14
Identity = 39/150 (26.00%), Postives = 72/150 (48.00%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+H+A           +I    N+  +D+     +H A   G+++++ LL+         DK + R +H+A   GH E+V++L+ N  +   ++ +   P+H A  SGHV +V+ L+  K  +   +  G T L +A  N  +  V  +L
Sbjct:   17 PLHVASANRAIKCADALIPLLSNVNVSDRAGRTALHHAAFNGNLEMVNLLISKGANVNAMDKRERRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLSLKAEMNEFNGFGNTALHVACHNGQDAVVSELL 166

HSP 4 Score: 65.4698 bits (158), Expect = 1.314e-11
Identity = 39/130 (30.00%), Postives = 67/130 (51.54%), Query Frame = 1

Query:  562 NDKD-NWK-PIHVACVYGHV---DILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            N +D NW+ P+HVA     +   D L  LL N       D+     +H+A   G++E+V +L+    N  + +  +RR +H+A   GH ++VK L+ N  ++  +D  G TPL  A  + +   V ++L+
Sbjct:    8 NARDKNWQTPLHVASANRAIKCADALIPLLSN---VNVSDRAGRTALHHAAFNGNLEMVNLLISKGANVNAMDKRERRAVHWAGYMGHTEVVKMLLSNGADVNWKDKKGYTPLHAAAASGHVTVVRLLLS 134

HSP 5 Score: 51.9878 bits (123), Expect = 1.996e-7
Identity = 36/125 (28.80%), Postives = 56/125 (44.80%), Query Frame = 1

Query:  580 KPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENN--CNFESQNIEKRRPIHYACKSGHVDIV-----KFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             P+H+A  +GH   L++LL      +  D +   P+  A   GH E V  L+ N       S    KR P+H A  S   +++     +  I    NL V     +TPL LA+ N +  CV +++
Sbjct:  461 SPLHLAAYHGHHQALEVLLRFVGEADLRDGHGRAPLELAAARGHTECVETLLANGACAGASSGTAAKRCPLHSAGGSAVAELLTIGKSRIKILGSINLFVR--TDRTPLMLAVTNGHTDCVLLLM 583

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374])

HSP 1 Score: 56.6102 bits (135), Expect = 4.830e-9
Identity = 30/104 (28.85%), Postives = 54/104 (51.92%), Query Frame = 1

Query:  586 IHVACVYGHVDILKLLLE-NNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIE--KRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLD 888
            + +AC  G  D++K ++E        +D      +H A   GH+EIV +L+EN  +   ++IE     P+  A  +GH+D+VK+L+ N  +  + +  G T  +
Sbjct:  334 LQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437

HSP 2 Score: 54.6842 bits (130), Expect = 2.148e-8
Identity = 29/92 (31.52%), Postives = 53/92 (57.61%), Query Frame = 1

Query:  487 IHIACWKGHCNIVKLMIDNDCNLQTNDKDNWK--PIHVACVYGHVDILKLLLENNCTTETE--DKYKTRPIHYACKTGHVEIVRILVENNCN 750
            + IAC KG  ++VK MI+ +     ND+DN     +H A + GH++I++LL+EN      +  + +   P+  A   GH+++V+ L++N  +
Sbjct:  334 LQIACDKGKYDVVKKMIE-EGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGAD 424

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Match: AVO2 (Component of a complex containing the Tor2p kinase and other proteins; complex may have a role in regulation of cell growth [Source:SGD;Acc:S000004672])

HSP 1 Score: 55.8398 bits (133), Expect = 5.098e-9
Identity = 45/155 (29.03%), Postives = 75/155 (48.39%), Query Frame = 1

Query:  496 ACWKGHCNIVKLMIDNDCNLQTN--DKDNWKPIHVACVYGHVDILKLLLE-NNCTTETEDKYKTRP-IHYACKTGHVEIVRILVENNCNFESQNIEK-RRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIE 945
            A  +G+  IVK ++  + +L TN   ++ W  +H A  +G   I   L++  +   E    +K    +H A   GH + + +L++    F +   E  R PIH AC + +   +  LI    +L V D +G TPL + LE  +  C+ M+L E E
Sbjct:   12 AIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGE 166

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Match: GDE1 (Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes [Source:SGD;Acc:S000006031])

HSP 1 Score: 56.6102 bits (135), Expect = 5.316e-9
Identity = 48/201 (23.88%), Postives = 90/201 (44.78%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILIN--KKCNIEQEM----------IWNIKPVHITCLVGNIEILRLLIA-----YRCDLESIANIPTDEN---------FEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDK-DNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRIL 732
            +H +C+ G  EV K++I   K+ NI  E+            ++ P+H+  L  + +   +L+       +    S+ ++ T+ N           K FDI+ +++E       +   P+++AC          ++ N  +L+  +K   W  I VA   G  DI+KLL+ NN   + ED+    P+ +A   GH+ I  ++
Sbjct:  432 LHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNE-------LHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625

HSP 2 Score: 56.225 bits (134), Expect = 5.849e-9
Identity = 50/214 (23.36%), Postives = 97/214 (45.33%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDS-ENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDN-DCNLQTNDKDNWKPIHVACVYGHVDILKLLLEN---NCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFE-SQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMI 930
            P+H +C  G  E+ +L+I    +      IP D       D+ +  ++ES++        P+H+     H    ++++ + D N++         +H+A  + +  +L +LL +   +   +  + ++T P++ AC+    E    L+ N  + E  + +     I  A   G  DIVK LI N  N ++ED  G TP++ A+   +    DM+
Sbjct:  431 PLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPID-------DVSAFGDAESLT--------PLHLCVLGAHPKTTEVLLQSLDPNVKLKSS---SLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHET-PLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMV 625

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Match: PHO81 (Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465])

HSP 1 Score: 55.8398 bits (133), Expect = 8.283e-9
Identity = 51/220 (23.18%), Postives = 97/220 (44.09%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCN---IVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACK-------------------TGHVEIVRILVENNCNF-ESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLAL 897
            P+H    +G +E +  L+     LE +  I +D     +  I + + + +  + T+           G  N   I K ++D   N+ ++ K  + P++VAC + + D  KLLLE   + +  D  K +   + C+                    G  +++++L+    +  E     K  PI YA +SGH +++  L+ +   L++ED +G +PL  AL
Sbjct:  427 PLHYAAELGKLEFVHSLLITNL-LEDVDPIDSDSKTPLVLAITNNHIDVVRDLLTI-----------GGANASPIEKPILDYSKNVISSTKVQFDPLNVACKFNNHDAAKLLLEIR-SKQNADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYAL 633

HSP 2 Score: 52.7582 bits (125), Expect = 8.374e-8
Identity = 35/155 (22.58%), Postives = 69/155 (44.52%), Query Frame = 1

Query:  445 SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIH------------------VACVYGHVDILKLLLENNCTTETEDKY-KTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNL 852
            S+++ +   VQ  P+++AC   + +  KL+++       ++  N    H                  VA + G   +++LL+         D + K  PI YA ++GH E++  L+++N   + ++     P+ YA    HVD++  L+    NL
Sbjct:  497 SKNVISSTKVQFDPLNVACKFNNHDAAKLLLEIRSKQNADNAKNKSSQHLCQPLFKKNSTGLCTLHIVAKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALLQRPLNL 651

HSP 3 Score: 46.595 bits (109), Expect = 7.106e-6
Identity = 38/154 (24.68%), Postives = 69/154 (44.81%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRC--DLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDN-WKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFES 759
            P+++ C   N +  +LL+  R   + ++  N  +    + LF    +NS  + T+  V       A   G   +++L+I    +    D  N W PI  A   GH +++  LL++N   + ED     P+ YA    HV+++  L++   N  S
Sbjct:  510 PLNVACKFNNHDAAKLLLEIRSKQNADNAKNKSSQHLCQPLF---KKNSTGLCTLHIV-------AKIGGDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALLQRPLNLPS 653

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464])

HSP 1 Score: 51.6026 bits (122), Expect = 4.602e-8
Identity = 37/143 (25.87%), Postives = 63/143 (44.06%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKP--IHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVE-NNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDID--GKTPLDLAL 897
            P HIAC  G+  +VK + D       N   N     +H+A      ++ + L+EN  +   +DK+   P+H A   G ++++ +L          Q+ +   P+ +A   GH D    L+  K   E + +D  G    D+AL
Sbjct:   75 PFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLV-EKYGAEYDLVDNKGAKAEDVAL 216

HSP 2 Score: 48.521 bits (114), Expect = 4.728e-7
Identity = 41/174 (23.56%), Postives = 73/174 (41.95%), Query Frame = 1

Query:  241 EVVKILINKKCNIE-----QEMIWNIKPVHITCLVGNIEILRLLI--AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLE-NNCTTETEDKYKTRPIHYACKTGHVEIVRILVE 738
            E+   L++K  N+       +  W   P HI C VGN+E+++ L     + DL  I N                  + ++ +        H+A  K    + + +I+N  +++  DK N  P+H A   G + +++LL          +DK    P+ +A   GH +   +LVE
Sbjct:   50 EITSFLLSKMENVNLDDYPDDSGWT--PFHIACSVGNLEVVKSLYDRPLKPDLNKITN------------------QGVTCL--------HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195

HSP 3 Score: 46.2098 bits (108), Expect = 3.327e-6
Identity = 31/127 (24.41%), Postives = 60/127 (47.24%), Query Frame = 1

Query:  565 DKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPI---HYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIH-NKCNLEVEDIDGKTPLDLAL-ENNNEICVDMI 930
            D   W P H+AC  G+++++K L +     +  +K   + +   H A      E+ + L+EN  +   ++   + P+H A   G + +++ L    K  +  +D  G TPL  AL E + +  V ++
Sbjct:   69 DDSGWTPFHIACSVGNLEVVKSLYDRPLKPDL-NKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLV 194

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Match: EDO38702 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC57])

HSP 1 Score: 83.9593 bits (206), Expect = 1.448e-17
Identity = 52/170 (30.59%), Postives = 88/170 (51.76%), Query Frame = 1

Query:  430 IDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWK--PIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNN-EICVDMI 930
            IDS+N E I+        PIH A   G    V  ++  D  +  ND+D     P+H+A ++GH  ++K LL      +  +     P+  A   G VE+  IL++ +   +  +  K  P+H A + GHV++VK L+  K N+ + D  G+  LD+A+E+++ E+ V +I
Sbjct:  276 IDSKNDEDIT--------PIHYAAKFGRVRTVCALLKRDPAI-INDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAII 436

HSP 2 Score: 63.1586 bits (152), Expect = 8.020e-11
Identity = 60/262 (22.90%), Postives = 117/262 (44.66%), Query Frame = 1

Query:  196 TQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIA---YRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNL----QTNDKDNWKPIHVA--CVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARK 954
            TQ   +HVAC  G + V K L+    ++       + P+H  C+ GN+ + +LL      R    +++ + TD++ E+                  QT  +H+A   GH ++ KL ++   N+    ++ +K   K I VA  C++  + + KL   + C +E   K K   + Y      V I+  ++      E ++ +K  P+  A +  HVD V+ L+ +  ++  +DI+ +  +        E C++ +   +E +K
Sbjct:    3 TQMTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREE------------------QT-ALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSE---KIKREILLYFFDV--VIIICYIIRFRACIECRDKDKDTPLMIAAEKNHVDTVRTLLQHGADIAAKDINDRNSV---FRAAAEGCMETLEAALEHQK 237

HSP 3 Score: 56.9954 bits (136), Expect = 8.102e-9
Identity = 48/205 (23.41%), Postives = 89/205 (43.41%), Query Frame = 1

Query:  463 MKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLL-----LENNCTTET-----EDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYA----------------------CKSGHVD------------IVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIE 945
            MKT Q  P+H+AC  G   + K +++   +L++ D++   P+H AC+ G++ + KLL     L    +T +     +D+ +   +H A + GH ++ ++ +E   N  +    K +  H                        CKS  +             I+ ++I  +  +E  D D  TPL +A E N+   VD + T ++
Sbjct:    1 MKT-QMTPLHVACSHGCIPVAKCLVEAGADLRSLDEEQMTPLHFACMEGNLGVAKLLFVAAELRGGWSTVSKMVTDQDREEQTALHLAVEGGHGDLAKLCLEKGANVNAVKESKNKTFHKTIVVARECIFVMIKVSKLKYLSFCKSEKIKREILLYFFDVVIIICYIIRFRACIECRDKDKDTPLMIAAEKNH---VDTVRTLLQ 201

HSP 4 Score: 49.2914 bits (116), Expect = 1.955e-6
Identity = 43/178 (24.16%), Postives = 76/178 (42.70%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKK-CNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVEN 741
            IH A K G V  V  L+ +    I  E   +  P+H+  L G+  +++ L+ YR                    ID+ N+       T+ T P+  A  +G   +  +++D D  +   DK    P+H+A   GHV+++KLLL         D      +  A ++ H E+   ++++
Sbjct:  287 IHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELL-YRGGA-----------------IDARNA-------TLWT-PLDCAAARGMVEVANILLDEDAPVDPTDKAKTTPLHLASREGHVEMVKLLLSRKANITLTDSAGRNCLDIAIESSHKEVAVAIIDH 438

HSP 5 Score: 47.7506 bits (112), Expect = 6.711e-6
Identity = 29/106 (27.36%), Postives = 49/106 (46.23%), Query Frame = 1

Query:  625 KLLLENNCTTETEDKYKTRPIHYACKTGHVEIV-RILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +LLL+N    ++++     PIHYA K G V  V  +L  +      ++     P+H A   GH  +VK L++    ++  +    TPLD A         +++L E
Sbjct:  267 QLLLDNGACIDSKNDEDITPIHYAAKFGRVRTVCALLKRDPAIINDEDGASNTPLHLAALHGHAAVVKELLYRGGAIDARNATLWTPLDCAAARGMVEVANILLDE 372

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Match: EDO49485 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG84])

HSP 1 Score: 72.7886 bits (177), Expect = 1.062e-14
Identity = 64/249 (25.70%), Postives = 98/249 (39.36%), Query Frame = 1

Query:  205 QAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNI--VKLMIDNDCNLQTNDKDNWKPIHVACVYG-HVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCN---FESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            Q +H+AC  GF E  K L+    ++  +   +  P+H     GN+  L LL++   D   I                            +   P+H A   GH N   V  ++    N+   D     P+H A         ++ LL N       DK     +HYA   GH   + +L++ + N     S       P+H A   GH   ++ LI +  +LEV D  G+TPLDLA    +  CV+ +L
Sbjct:    2 QPLHLACLGGFTECCKKLLFYGVDVNAKDNNDRTPLHCAACSGNVNCLELLMSQAGDFNCI--------------------------DKLGRNPLHYA--AGHTNFRCVMSLVTAGSNVNKPDTKACTPLHYAAASDLDAKCVEHLLRNRGNASKRDKQGYSAVHYASANGHKLAIEMLLDVSANDLLNRSSGSPCVTPLHLAAFHGHKPALEVLIKSFNDLEVRDDRGRTPLDLASFQGHVECVECLL 222

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Match: EDO43690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXV8])

HSP 1 Score: 73.559 bits (179), Expect = 1.078e-14
Identity = 63/250 (25.20%), Postives = 112/250 (44.80%), Query Frame = 1

Query:   40 RTRFKFQITF*MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN---IPTD----ENFEKLFDIDSENSE-SISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQN 765
            R+R K +I F        N+  VF   V SG+V EVKK L K     ++       A+H AC     ++VK+L++K  +++         +H     G++EI + LI    D+ ++ N   +P D    E+ E L   + EN    +   + V+ + +         N  +  ++ +C  ++ DK     +HVA   G++ ++ LLL+       +D     P+H A   G  +   +L EN  +F ++N
Sbjct:   38 RSRKKPKIQF--------NSGIVFLSAVSSGDVDEVKKLLAK-GADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDMEDLLTDEIENQGIDVDDARAVEEKIM--------LNDAQSWLNKNCINESKDKTEASALHVASSKGYLKVIGLLLQLGVEINAKDADNWTPLHAAAHWGQKDACELLSENGADFNARN 270

HSP 2 Score: 59.6918 bits (143), Expect = 5.742e-10
Identity = 36/127 (28.35%), Postives = 64/127 (50.39%), Query Frame = 1

Query:  595 ACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMR 975
            A   G VD +K LL        ++      +H AC   + ++V++LV+   + + ++ E    +H A   G V+I K+LI N  ++   + +G+ PLDLA E + E   D++  EIE +   + + R
Sbjct:   56 AVSSGDVDEVKKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAEEEDME---DLLTDEIENQGIDVDDAR 179

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Match: EDO28178 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T774])

HSP 1 Score: 70.4774 bits (171), Expect = 4.995e-14
Identity = 48/171 (28.07%), Postives = 76/171 (44.44%), Query Frame = 1

Query:  388 ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQT-NDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFE-SQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            AN+PT+ N E       EN++++S                GH  +  +++D+   +   +D +   P+  AC  GH D+++LLL  +   E   K    P+ +A   GH ++   L+E               P+  AC  GH D+VK L+    N+E    DG TPL LA
Sbjct:   35 ANVPTNTNREYCHAKILENNKTMSRDALA-----------GHVKVATMLLDHGAEINVESDSNKDSPLTFACWKGHCDVVELLLARSANIEHRTKEGFTPLMFAALGGHTDVAAKLLEQGAKVNIPSGSNNDIPLTSACWKGHHDVVKLLLKYTSNIEHRTKDGCTPLMLA 194

HSP 2 Score: 67.3958 bits (163), Expect = 5.174e-13
Identity = 31/107 (28.97%), Postives = 55/107 (51.40%), Query Frame = 1

Query:  484 PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTR-PIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACK 801
            P+  ACWKGHC++V+L++    N++   K+ + P+  A + GH D+   LLE               P+  AC  GH ++V++L++   N E +  +   P+  A +
Sbjct:   90 PLTFACWKGHCDVVELLLARSANIEHRTKEGFTPLMFAALGGHTDVAAKLLEQGAKVNIPSGSNNDIPLTSACWKGHHDVVKLLLKYTSNIEHRTKDGCTPLMLAAR 196

HSP 3 Score: 53.1434 bits (126), Expect = 3.912e-8
Identity = 35/134 (26.12%), Postives = 61/134 (45.52%), Query Frame = 1

Query:  571 DNWKPIHVACVYGHVDILKLLLENNCTTETE-DKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEV-EDIDGKTPLDLALENNNEICVDMIL---TEIEARKK 957
            +N K +    + GHV +  +LL++      E D  K  P+ +AC  GH ++V +L+  + N E +  E   P+ +A   GH D+   L+     + +    +   PL  A    +   V ++L   + IE R K
Sbjct:   52 ENNKTMSRDALAGHVKVATMLLDHGAEINVESDSNKDSPLTFACWKGHCDVVELLLARSANIEHRTKEGFTPLMFAALGGHTDVAAKLLEQGAKVNIPSGSNNDIPLTSACWKGHHDVVKLLLKYTSNIEHRTK 185

HSP 4 Score: 52.373 bits (124), Expect = 7.307e-8
Identity = 35/129 (27.13%), Postives = 58/129 (44.96%), Query Frame = 1

Query:  220 ACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVY 606
            AC +G  +VV++L+ +  NIE        P+    L G+ ++   L+    +  +  NIP+  N     DI                 P+  ACWKGH ++VKL++    N++   KD   P+ +A  Y
Sbjct:   94 ACWKGHCDVVELLLARSANIEHRTKEGFTPLMFAALGGHTDVAAKLL----EQGAKVNIPSGSNN----DI-----------------PLTSACWKGHHDVVKLLLKYTSNIEHRTKDGCTPLMLAARY 197

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Match: EDO43381 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYU3])

HSP 1 Score: 72.0182 bits (175), Expect = 2.155e-13
Identity = 49/160 (30.63%), Postives = 78/160 (48.75%), Query Frame = 1

Query:  445 SESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQT-NDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICV 921
            SES +  +T  +  IH A  KG    +K +I     +++  D+     +H+A   GH+D +K L  +      E       IH A   GHV  + IL         + ++ + P+H A  SGH++ VK+L+ N+   E ED +G+T LD+A E  +E  V
Sbjct:  893 SESENVFRTGPS--IHDAAKKGDLARIKELIGVAPAMKSVPDEKGMTALHIASSNGHLDCVKWLAVSGVDLGQETPTGYTAIHLAAMGGHVNCMMILSAMGSVVNCKTVDDQTPLHLAAMSGHLECVKWLLANRSRTEAEDSNGRTALDIAEEYGHEDIV 1050

HSP 2 Score: 48.9062 bits (115), Expect = 3.930e-6
Identity = 32/139 (23.02%), Postives = 58/139 (41.73%), Query Frame = 1

Query:  208 AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDIL 624
            A+H+A   G ++ VK L     ++ QE       +H+  + G++  + +L A    + S+ N  T         +D +              P+H+A   GH   VK ++ N    +  D +    + +A  YGH DI+
Sbjct:  938 ALHIASSNGHLDCVKWLAVSGVDLGQETPTGYTAIHLAAMGGHVNCMMILSA----MGSVVNCKT---------VDDQT-------------PLHLAAMSGHLECVKWLLANRSRTEAEDSNGRTALDIAEEYGHEDIV 1050

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Match: dapk1 (death associated protein kinase 1 [Source:NCBI gene;Acc:101162667])

HSP 1 Score: 117.857 bits (294), Expect = 7.997e-28
Identity = 76/303 (25.08%), Postives = 142/303 (46.86%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-------------------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTV 1038
            N  +   A++ A + G VE ++ L  KKC +  +       +H+    GN+++    ++Y C +++  N+   E    L                    D+++ N E  S + T   R        G  +IV+ ++++  +LQ  DKD    +H+A     VD+++ LL++NC  + +D++    +H ACK G++ IV  +     N +  N   R P+H A K+G +++V+ L     N++    DGKT  DLA  + +E  V ++       K K   ++ +F+   RP  S + R+K+ +
Sbjct:  334 NDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDV----VSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASAR--------GFVDIVECLVEHRADLQATDKDGHTALHLAVRRCQVDVVRCLLKHNCQQDQQDRHGNTALHIACKDGNLPIVIAICGAKANLDLPNKHGRTPLHLAAKNGSLEVVRHLCLAGANIDAVTNDGKTAEDLASADRHEPIVSLL------SKLKKDNLKLSFIQQLRPTQSVQPRIKLKL 618

HSP 2 Score: 77.7962 bits (190), Expect = 7.717e-15
Identity = 54/208 (25.96%), Postives = 91/208 (43.75%), Query Frame = 1

Query:  376 LESIANIPTDENFEKLFDI-DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIV---------------------------------RILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLAL 897
            +++I +   D+N   L  +  S NS  I+      T P+ IA   G+  I+++++     +Q NDK     ++ A  +GHV+ L+ L E  C    +DK     +H A + G+V++V                                 R L +  C+  + N E   P+  A   G VDIV+ L+ ++ +L+  D DG T L LA+
Sbjct:  271 MKAIIHAINDDNVPGLQHLLGSLNSYDINQPNKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASARGFVDIVECLVEHRADLQATDKDGHTALHLAV 478

HSP 3 Score: 55.0694 bits (131), Expect = 1.320e-7
Identity = 26/91 (28.57%), Postives = 48/91 (52.75%), Query Frame = 1

Query:  664 DKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +K+ T P+  A   G+++I+ +L+      ++ +      ++YA + GHV+ ++FL   KC L V+D  G+T L +A    N   V  + T
Sbjct:  302 NKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCT 392

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Match: dapk1 (death associated protein kinase 1 [Source:NCBI gene;Acc:101162667])

HSP 1 Score: 117.472 bits (293), Expect = 1.050e-27
Identity = 76/303 (25.08%), Postives = 142/303 (46.86%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-------------------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTV 1038
            N  +   A++ A + G VE ++ L  KKC +  +       +H+    GN+++    ++Y C +++  N+   E    L                    D+++ N E  S + T   R        G  +IV+ ++++  +LQ  DKD    +H+A     VD+++ LL++NC  + +D++    +H ACK G++ IV  +     N +  N   R P+H A K+G +++V+ L     N++    DGKT  DLA  + +E  V ++       K K   ++ +F+   RP  S + R+K+ +
Sbjct:  402 NDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDV----VSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASAR--------GFVDIVECLVEHRADLQATDKDGHTALHLAVRRCQVDVVRCLLKHNCQQDQQDRHGNTALHIACKDGNLPIVIAICGAKANLDLPNKHGRTPLHLAAKNGSLEVVRHLCLAGANIDAVTNDGKTAEDLASADRHEPIVSLL------SKLKKDNLKLSFIQQLRPTQSVQPRIKLKL 686

HSP 2 Score: 77.411 bits (189), Expect = 9.571e-15
Identity = 54/208 (25.96%), Postives = 91/208 (43.75%), Query Frame = 1

Query:  376 LESIANIPTDENFEKLFDI-DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIV---------------------------------RILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLAL 897
            +++I +   D+N   L  +  S NS  I+      T P+ IA   G+  I+++++     +Q NDK     ++ A  +GHV+ L+ L E  C    +DK     +H A + G+V++V                                 R L +  C+  + N E   P+  A   G VDIV+ L+ ++ +L+  D DG T L LA+
Sbjct:  339 MKAIIHAINDDNVPGLQHLLGSLNSYDINQPNKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASARGFVDIVECLVEHRADLQATDKDGHTALHLAV 546

HSP 3 Score: 54.6842 bits (130), Expect = 1.427e-7
Identity = 26/91 (28.57%), Postives = 48/91 (52.75%), Query Frame = 1

Query:  664 DKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +K+ T P+  A   G+++I+ +L+      ++ +      ++YA + GHV+ ++FL   KC L V+D  G+T L +A    N   V  + T
Sbjct:  370 NKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCT 460

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Match: dapk1 (death associated protein kinase 1 [Source:NCBI gene;Acc:101162667])

HSP 1 Score: 117.472 bits (293), Expect = 1.101e-27
Identity = 76/303 (25.08%), Postives = 142/303 (46.86%), Query Frame = 1

Query:  187 NPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLF-------------------DIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTV 1038
            N  +   A++ A + G VE ++ L  KKC +  +       +H+    GN+++    ++Y C +++  N+   E    L                    D+++ N E  S + T   R        G  +IV+ ++++  +LQ  DKD    +H+A     VD+++ LL++NC  + +D++    +H ACK G++ IV  +     N +  N   R P+H A K+G +++V+ L     N++    DGKT  DLA  + +E  V ++       K K   ++ +F+   RP  S + R+K+ +
Sbjct:  408 NDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDV----VSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASAR--------GFVDIVECLVEHRADLQATDKDGHTALHLAVRRCQVDVVRCLLKHNCQQDQQDRHGNTALHIACKDGNLPIVIAICGAKANLDLPNKHGRTPLHLAAKNGSLEVVRHLCLAGANIDAVTNDGKTAEDLASADRHEPIVSLL------SKLKKDNLKLSFIQQLRPTQSVQPRIKLKL 692

HSP 2 Score: 77.411 bits (189), Expect = 9.838e-15
Identity = 54/208 (25.96%), Postives = 91/208 (43.75%), Query Frame = 1

Query:  376 LESIANIPTDENFEKLFDI-DSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIV---------------------------------RILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLAL 897
            +++I +   D+N   L  +  S NS  I+      T P+ IA   G+  I+++++     +Q NDK     ++ A  +GHV+ L+ L E  C    +DK     +H A + G+V++V                                 R L +  C+  + N E   P+  A   G VDIV+ L+ ++ +L+  D DG T L LA+
Sbjct:  345 MKAIIHAINDDNVPGLQHLLGSLNSYDINQPNKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCTIQADPNLADREQEIPLHCAAWHGYSAVARALCQAGCDVNATNREGESPLLTASARGFVDIVECLVEHRADLQATDKDGHTALHLAV 552

HSP 3 Score: 54.6842 bits (130), Expect = 1.465e-7
Identity = 26/91 (28.57%), Postives = 48/91 (52.75%), Query Frame = 1

Query:  664 DKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            +K+ T P+  A   G+++I+ +L+      ++ +      ++YA + GHV+ ++FL   KC L V+D  G+T L +A    N   V  + T
Sbjct:  376 NKHGTPPLLIAAGCGNIQIIEVLMRKGAEIQANDKSGANAVYYAARHGHVETLRFLHEKKCPLNVQDKSGETALHVAARYGNVDVVSYLCT 466

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Match: ENSORLT00000040233.1 (pep primary_assembly:ASM223467v1:19:16412534:16434057:1 gene:ENSORLG00000021910.1 transcript:ENSORLT00000040233.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.694 bits (278), Expect = 1.381e-26
Identity = 71/287 (24.74%), Postives = 136/287 (47.39%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESI-------STMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V EV   L K+  + D        A+H+A   G  EVVK L++   N+  +      P+++     ++++++LL+    +  S  +I T++ F  L     +  + +        T   V+   +HIA  K       L++ ND N     K  + P+H+A  YG++++  LLL      + + +    P+H A K G+  +VR+L+E     +++  +   P+H A +SGH  +V+ L++    +  +  +G +PL +A + ++  CV ++L
Sbjct:   49 NGLNALHLASKEGHV-EVVAELIKQGANVDAATKKGNTALHIASLAGQTEVVKELVSNGANVNAQSQNGFTPLYMAAQENHLDVVQLLL----ENGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVRLLLERGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLLL 330

HSP 2 Score: 90.5077 bits (223), Expect = 2.515e-19
Identity = 57/255 (22.35%), Postives = 112/255 (43.92%), Query Frame = 1

Query:  169 FLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
             L +D     +  A+H+A ++   +   +L+    N + E      P+HI    GNI +  LL+          N     +F+   DI                 P+H+A  +G+ N+V+L+++    +    KD   P+H A   GH  ++++LL       ++ K    P+H A +  H+  V++L+ ++   +    +    +H A   GH  + K ++  K N   + ++G TPL +A + N    ++++L
Sbjct:  168 LLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLL----------NRGAAVDFKARNDI----------------TPLHVASKRGNSNMVRLLLERGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLL 396

HSP 3 Score: 87.8113 bits (216), Expect = 2.288e-18
Identity = 51/239 (21.34%), Postives = 111/239 (46.44%), Query Frame = 1

Query:  178 SDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            S F P      +H+A   G + V  +L+N+   ++ +   +I P+H+    GN  ++RLL+                  E+   ID+   + ++        P+H A   GH  +V+++++    + +  K+   P+H+A    H++ ++LLL ++   +         +H A   GH ++ +++V+   N  ++ +    P+H ACK   V +++ L+ +  +++     G TP+ +A
Sbjct:  210 SGFTP------LHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVRLLL------------------ERGSKIDARTKDGLT--------PLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASIQAVTESGLTPIHVA 416

HSP 4 Score: 72.7886 bits (177), Expect = 1.693e-13
Identity = 34/133 (25.56%), Postives = 68/133 (51.13%), Query Frame = 1

Query:  535 IDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            + N  ++   +++    +H+A   GHV+++  L++     +   K     +H A   G  E+V+ LV N  N  +Q+     P++ A +  H+D+V+ L+ N  +  +   DG TPL +AL+  ++  V ++L
Sbjct:   37 LQNGVDINICNQNGLNALHLASKEGHVEVVAELIKQGANVDAATKKGNTALHIASLAGQTEVVKELVSNGANVNAQSQNGFTPLYMAAQENHLDVVQLLLENGSSQSIATEDGFTPLAVALQQGHDQVVSLLL 169

HSP 5 Score: 64.6994 bits (156), Expect = 7.330e-11
Identity = 57/298 (19.13%), Postives = 115/298 (38.59%), Query Frame = 1

Query:  409 NFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKC-----------------------------NLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPERNI------CKICYDREVDCVLSCGHVFCMLCGKRFSICPVCRTKSTNHI 1197
            N EK  D   +N   I+         +H+A  +GH  +V  +I    N+    K     +H+A + G  +++K L+ N      + +    P++ A +  H+++V++L+EN  +      +   P+  A + GH  +V  L+ N                               N +VE   G TPL +A    N     ++L    A   K          A + G S   R+ +   ++I+ + +  +       +  +++ V+ +L+ G    +L   +  + P+      +H+
Sbjct:   29 NLEKALDY-LQNGVDINICNQNGLNALHLASKEGHVEVVAELIKQGANVDAATKKGNTALHIASLAGQTEVVKELVSNGANVNAQSQNGFTPLYMAAQENHLDVVQLLLENGSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFKARNDITPLHVASKRGNSNMVRLLLERGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRG--APILSKTKNGLSPLHMATQGDHL 323

HSP 6 Score: 63.929 bits (154), Expect = 1.249e-10
Identity = 41/203 (20.20%), Postives = 87/203 (42.86%), Query Frame = 1

Query:  181 DFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNI 768
            DF        +HVA K+G   +V++L+ +   I+      + P+H     G+ +++ +L+     + S         ++ T  +      +   +   +  +       +H+A   GH  + K+++D   N      + + P+H+AC    V +++LLL++  + +   +    PIH A   GH  IV  L+    +  + N+
Sbjct:  238 DFKARNDITPLHVASKRGNSNMVRLLLERGSKIDARTKDGLTPLHCAARSGHEQVVEMLLNRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLHHDVPVDDVTNDYLTALHVAAHCGHYKVAKVIVDKKANPNAKALNGFTPLHIACKKNRVKVMELLLKHGASIQAVTESGLTPIHVAAFMGHENIVHQLINYGASPNTSNV 440

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Match: ank1a (ankyrin-1 [Source:NCBI gene;Acc:101174837])

HSP 1 Score: 111.309 bits (277), Expect = 1.195e-25
Identity = 72/280 (25.71%), Postives = 132/280 (47.14%), Query Frame = 1

Query:  130 GNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESI----------ANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            G+ M+  K+L +     D         +HVA   G   + K+L++K        +    P+HI C   ++ ++ LL+ +   +E++          A+     N  K+  +    S S S +K V+T P+H+A   GH  + + ++ N   +    KD+  P+H A   GH +++KLLLE+     +       P+H A + GHV+ VR+L++          +   P+H A K G VD+ + L+    N      +G TPL +A+ +NN   V++++++
Sbjct:  253 GDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKIL-LQKGASPSASNVK-VET-PLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSK 529

HSP 2 Score: 110.538 bits (275), Expect = 2.247e-25
Identity = 56/260 (21.54%), Postives = 132/260 (50.77%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISE 969
            +H A + G   +++IL++    I+ +    + P+H+     +++ ++ L+ Y  +++ I        ++       ++  +  +     ++       P+HIAC K H  ++ L++ +  +++   +    P+HVA   GH++I+K+LL+   +    +     P+H A ++GH E+   L++N    +++  + + P+H A + GH ++VK L+ +K N       G +PL +A    +   V ++L ++EA++ K+++
Sbjct:  214 LHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLL-DMEAQQTKMTK 472

HSP 3 Score: 103.99 bits (258), Expect = 2.806e-23
Identity = 61/235 (25.96%), Postives = 115/235 (48.94%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            IH+A +   ++ VK L+     I+   + ++ P+H+    G+  + ++L+       S A       +I   +N  ++ D+  ++S SI  +      P+H+A + GH NIVK+++    +   ++     P+H+A   GH ++ + LL+N    + + K    P+H A + GH E+V++L+E+  N  S       P+H A + GHV  V+ L+  +         G TPL +A
Sbjct:  247 IHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVA 481

HSP 4 Score: 95.5153 bits (236), Expect = 1.553e-20
Identity = 62/250 (24.80%), Postives = 113/250 (45.20%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI-------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +HVA   G + +VKIL+ K  +     +    P+H+    G+ E+   L+       A   D ++  +       ++L  +  E+  + ++  T    P+HIA  +GH   V+L++D +       K  + P+HVA  YG VD+ +LLLE         K    P+H A    ++++V +LV    +  S        +H A K   V++   L+ +  +   E + G TPL LA +      V +++++
Sbjct:  346 LHVASFMGHLNIVKILLQKGASPSASNVKVETPLHMASRSGHFEVAEFLLQNAAPVDAKAKDDQTPLHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISK 595

HSP 5 Score: 93.2041 bits (230), Expect = 8.840e-20
Identity = 56/243 (23.05%), Postives = 112/243 (46.09%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTE 939
            +H A + G  E+VK+L+  K N          P+HI    G+++ +RLL+    D+E+     T + F                       P+H+A   G  ++ +L+++   N     K+   P+HVA  + ++D++ LL+    +  +  +     +H A K   VE+   L+++  +  +++++   P+H A + G  DIV  LI  + N+ + +  G TPL L  +  +    D+++ +
Sbjct:  412 LHCAARMGHKELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLL----DMEAQQTKMTKKGFT----------------------PLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQ 628

HSP 6 Score: 90.5077 bits (223), Expect = 7.371e-19
Identity = 66/287 (23.00%), Postives = 127/287 (44.25%), Query Frame = 1

Query:  106 VFEKVVKSGNV------MEVKKRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDID-------SENSESISTMKTVQTR-------PIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLA 894
            V E   K GN       +  ++++  E ++   N   Q Q     +++A ++  +EVVK L+    N          P+ +    G+  ++ LLI+Y    +    +P   +F     +        + + E+++  + +  R       P+H A   GH  I+++++DN   +Q   K+   PIH+A    H+D +K LL+ N   +        P+H A   GH  + ++L++      S+ +    P+H ACK  H+ ++  L+ +  ++E     G TPL +A
Sbjct:   65 VLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISY--GTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGANDELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLLKHSASIEAVTESGLTPLHVA 349

HSP 7 Score: 89.7373 bits (221), Expect = 1.154e-18
Identity = 72/308 (23.38%), Postives = 132/308 (42.86%), Query Frame = 1

Query:   94 NNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQ----AIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIAN--IPTDENFEKLFDIDSENSESISTM----------------------KTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            N L       K G+V     ++  E LH+     T  +    A+H+A   G  +VV  L+N   N+  +      P+++     ++E+++ L      LE+ AN  IPT++ F  L     +  E++  +                            P+HIA    + N+ +L+++   N      D   P+H A   GH  I+++LL+N    + + K    PIH A +  H++ V+ L++ N   +   ++   P+H A   GH  + K L+          ++G TPL +A + N+   +D++L
Sbjct:   39 NGLNALHLASKEGHV-----KMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFL------LENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYENLNVAQLLLNRGAN------DELTPLHCAARNGHFRIIEILLDNGAPIQAKTKNGLSPIHMAAQGDHMDCVKQLLQYNAEIDDITLDHLTPLHVAAHCGHHRMAKVLLDKGAKPNSRALNGFTPLHIACKKNHLRVMDLLL 329

HSP 8 Score: 77.7962 bits (190), Expect = 7.718e-15
Identity = 49/210 (23.33%), Postives = 97/210 (46.19%), Query Frame = 1

Query:  211 IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIA-------NIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYA---CKSGH 810
            +HVA K G V+V ++L+ +  N        + P+H+     N++++ LL++      S A       +I   +N  ++ +   ++  S +        P+H+A  +G  +IV L+I    N+   +K    P+H+    GHV I  +L++   +     +    P+H AC  G++++V+ L++   N  S+   +    HY    C+  H
Sbjct:  478 LHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYTALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANVNSKTRVEYIQCHYKDHYCEYKH 687

HSP 9 Score: 76.6406 bits (187), Expect = 1.987e-14
Identity = 55/246 (22.36%), Postives = 104/246 (42.28%), Query Frame = 1

Query:  151 KRLKKEFLHSDFNPFTQCQA----IHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLI--------AYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNL 852
            K L K  L    NP +   A    +H+A ++G V+ V++L++ +    +       P+H+    G +++  LL+        A +  L  +       N + +  + S+     S  +   T  +HIA  +    +   ++ +  +          P+H+A   G  DI+ LL+         +K    P+H   + GHV I  ILV+   +  +       P+H AC  G++ +VKFL+  + N+
Sbjct:  421 KELVKLLLEHKANPNSTTTAGHSPLHIAAREGHVQTVRLLLDMEAQQTKMTKKGFTPLHVASKYGKVDVAELLLERGANPNAAGKNGLTPLHVAVHHNNLDVVNLLVSKGGSPHSAARNGYT-ALHIAAKQNQVEVANSLLQHGASANAESLQGVTPLHLASQEGRPDIVSLLISKQANVNLGNKSGLTPLHLVAQEGHVGIADILVKQGASVYAATRMGYTPLHVACHYGNIKMVKFLLQQQANV 665

HSP 10 Score: 75.0998 bits (183), Expect = 6.313e-14
Identity = 40/134 (29.85%), Postives = 70/134 (52.24%), Query Frame = 1

Query:  535 IDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILT 936
            I N  ++ T +++    +H+A   GHV ++  LL N    ET  K     +H A   G  ++V  LV    N  +Q+ +   P++ A +  H+++VKFL+ N  N  +   DG TPL +AL+  +E  V ++++
Sbjct:   27 IKNGIDINTANQNGLNALHLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLIS 160

HSP 11 Score: 58.151 bits (139), Expect = 1.310e-8
Identity = 40/179 (22.35%), Postives = 76/179 (42.46%), Query Frame = 1

Query:  406 ENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVE-----------DIDGKTPLDLALENNN 909
            E+ +   DI++ N   ++ +        H+A  +GH  +V  ++ N   L+T  K     +H+A + G   ++  L+        + +    P++ A +  H+E+V+ L+EN  N      +   P+  A + GH ++V  LI      +V             + G TPL +A    N
Sbjct:   25 EHIKNGIDINTANQNGLNAL--------HLASKEGHVKMVLELLHNGIVLETTTKKGNTALHIAALAGQEQVVTELVNYGTNVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQSIPTEDGFTPLAVALQQGHENVVALLISYGTKGKVRLPALTDFCFFLSVTGFTPLHIAAHYEN 195

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Match: SMESG000021295.1 (SMESG000021295.1)

HSP 1 Score: 775.393 bits (2001), Expect = 0.000e+0
Identity = 380/380 (100.00%), Postives = 380/380 (100.00%), Query Frame = 1

Query:   73 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPERNICKICYDREVDCVLSCGHVFCMLCGKRFSICPVCRTKSTNHIRMFLD 1212
            MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPERNICKICYDREVDCVLSCGHVFCMLCGKRFSICPVCRTKSTNHIRMFLD
Sbjct:    1 MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEMRQAFVDAPRPGPSTKERMKVTVKARIETKPERNICKICYDREVDCVLSCGHVFCMLCGKRFSICPVCRTKSTNHIRMFLD 380

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Match: SMESG000040665.1 (SMESG000040665.1)

HSP 1 Score: 202.216 bits (513), Expect = 2.813e-59
Identity = 102/267 (38.20%), Postives = 156/267 (58.43%), Query Frame = 1

Query:  130 GNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMI 930
            GN   V   + + F++   +       IH+AC++GF  +V++L+   CNIE E     +P+H     G+ +++RLLI   C++E                   E+ E        Q RPIH A W GH ++V+L+ID +CN++  DK   +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++ E+RRPIHYAC +GH +I++ L+ NKC +E +   GKTPLDLA   N   C +++
Sbjct:    7 GNAEGVSNNISETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIEC------------------EDDE--------QVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLMLNKCQIECKTKGGKTPLDLARLYNKMDCAELL 247

HSP 2 Score: 157.918 bits (398), Expect = 9.531e-43
Identity = 76/209 (36.36%), Postives = 120/209 (57.42%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+HI C  G   I++LL+ + C++E                              +Q RPIH A   GH ++V+L+ID +CN++  D +  +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED + + P+  A  N +   + +++
Sbjct:   33 PIHIACEKGFFSIVQLLMEHNCNIE--------------------------CEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLM 215

HSP 3 Score: 147.517 bits (371), Expect = 4.777e-39
Identity = 70/166 (42.17%), Postives = 107/166 (64.46%), Query Frame = 1

Query:  436 SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            SE   ++ +   V   PIHIAC KG  +IV+L+++++CN++  DK   +PIH A  YGH D+++LL++ NC  E ED  + RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED   + P+  A  N +   V +++
Sbjct:   17 SETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLI 182

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Match: SMESG000040665.1 (SMESG000040665.1)

HSP 1 Score: 202.216 bits (513), Expect = 5.756e-59
Identity = 102/267 (38.20%), Postives = 156/267 (58.43%), Query Frame = 1

Query:  130 GNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMI 930
            GN   V   + + F++   +       IH+AC++GF  +V++L+   CNIE E     +P+H     G+ +++RLLI   C++E                   E+ E        Q RPIH A W GH ++V+L+ID +CN++  DK   +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++ E+RRPIHYAC +GH +I++ L+ NKC +E +   GKTPLDLA   N   C +++
Sbjct:    7 GNAEGVSNNISETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIEC------------------EDDE--------QVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLMLNKCQIECKTKGGKTPLDLARLYNKMDCAELL 247

HSP 2 Score: 157.918 bits (398), Expect = 1.516e-42
Identity = 76/209 (36.36%), Postives = 120/209 (57.42%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+HI C  G   I++LL+ + C++E                              +Q RPIH A   GH ++V+L+ID +CN++  D +  +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED + + P+  A  N +   + +++
Sbjct:   33 PIHIACEKGFFSIVQLLMEHNCNIE--------------------------CEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLM 215

HSP 3 Score: 147.517 bits (371), Expect = 6.729e-39
Identity = 70/166 (42.17%), Postives = 107/166 (64.46%), Query Frame = 1

Query:  436 SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            SE   ++ +   V   PIHIAC KG  +IV+L+++++CN++  DK   +PIH A  YGH D+++LL++ NC  E ED  + RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED   + P+  A  N +   V +++
Sbjct:   17 SETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLI 182

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Match: SMESG000040665.1 (SMESG000040665.1)

HSP 1 Score: 201.83 bits (512), Expect = 8.069e-59
Identity = 102/267 (38.20%), Postives = 156/267 (58.43%), Query Frame = 1

Query:  130 GNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMI 930
            GN   V   + + F++   +       IH+AC++GF  +V++L+   CNIE E     +P+H     G+ +++RLLI   C++E                   E+ E        Q RPIH A W GH ++V+L+ID +CN++  DK   +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++ E+RRPIHYAC +GH +I++ L+ NKC +E +   GKTPLDLA   N   C +++
Sbjct:    7 GNAEGVSNNISETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIEC------------------EDDE--------QVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLMLNKCQIECKTKGGKTPLDLARLYNKMDCAELL 247

HSP 2 Score: 157.147 bits (396), Expect = 2.331e-42
Identity = 76/209 (36.36%), Postives = 120/209 (57.42%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+HI C  G   I++LL+ + C++E                              +Q RPIH A   GH ++V+L+ID +CN++  D +  +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED + + P+  A  N +   + +++
Sbjct:   33 PIHIACEKGFFSIVQLLMEHNCNIE--------------------------CEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLM 215

HSP 3 Score: 147.132 bits (370), Expect = 1.042e-38
Identity = 70/166 (42.17%), Postives = 107/166 (64.46%), Query Frame = 1

Query:  436 SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            SE   ++ +   V   PIHIAC KG  +IV+L+++++CN++  DK   +PIH A  YGH D+++LL++ NC  E ED  + RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED   + P+  A  N +   V +++
Sbjct:   17 SETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLI 182

[Close]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Match: SMESG000040665.1 (SMESG000040665.1)

HSP 1 Score: 201.83 bits (512), Expect = 1.439e-58
Identity = 102/267 (38.20%), Postives = 156/267 (58.43%), Query Frame = 1

Query:  130 GNVMEVKKRLKKEFLHSDFNPFTQCQAIHVACKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMI 930
            GN   V   + + F++   +       IH+AC++GF  +V++L+   CNIE E     +P+H     G+ +++RLLI   C++E                   E+ E        Q RPIH A W GH ++V+L+ID +CN++  DK   +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++ E+RRPIHYAC +GH +I++ L+ NKC +E +   GKTPLDLA   N   C +++
Sbjct:    7 GNAEGVSNNISETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIEC------------------EDDE--------QVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLMLNKCQIECKTKGGKTPLDLARLYNKMDCAELL 247

HSP 2 Score: 157.532 bits (397), Expect = 3.151e-42
Identity = 76/209 (36.36%), Postives = 120/209 (57.42%), Query Frame = 1

Query:  307 PVHITCLVGNIEILRLLIAYRCDLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            P+HI C  G   I++LL+ + C++E                              +Q RPIH A   GH ++V+L+ID +CN++  D +  +PIH A   GH D+++LL++ NC  E EDK++ RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED + + P+  A  N +   + +++
Sbjct:   33 PIHIACEKGFFSIVQLLMEHNCNIE--------------------------CEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDNEQRRPIHYACWNGHAEIIQLLM 215

HSP 3 Score: 147.132 bits (370), Expect = 1.285e-38
Identity = 70/166 (42.17%), Postives = 107/166 (64.46%), Query Frame = 1

Query:  436 SENSESISTMKTVQTRPIHIACWKGHCNIVKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKYKTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIVKFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMIL 933
            SE   ++ +   V   PIHIAC KG  +IV+L+++++CN++  DK   +PIH A  YGH D+++LL++ NC  E ED  + RPIHYA   GH ++VR+L++ NCN E ++  +RRPIHYA  +GH D+V+ LI   CN+E ED   + P+  A  N +   V +++
Sbjct:   17 SETFVNVKSDAEVGKLPIHIACEKGFFSIVQLLMEHNCNIECEDKLQRRPIHWASRYGHADVVRLLIDRNCNIECEDDEQVRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLIDRNCNIECEDKWQRRPIHYASWNGHADVVRLLI 182

The following BLAST results are available for this feature:

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANK3	1.974e-25	23.00	ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]	[more]
ANK2	2.300e-25	25.09	ankyrin 2 [Source:HGNC Symbol;Acc:HGNC:493]	[more]
ANK1	5.022e-25	23.70	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]
ANK1	5.022e-25	23.70	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]
ANK1	5.615e-25	23.70	ankyrin 1 [Source:HGNC Symbol;Acc:HGNC:492]	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc-44	3.123e-22	25.00	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.123e-22	25.00	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.161e-22	25.00	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.161e-22	25.00	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]
unc-44	3.170e-22	25.00	AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ank2	2.192e-25	22.35	gene:FBgn0261788 transcript:FBtr0303119	[more]
Ank	5.141e-25	25.20	gene:FBgn0011747 transcript:FBtr0089172	[more]
Ank	5.141e-25	25.20	gene:FBgn0011747 transcript:FBtr0300497	[more]
Ank	5.141e-25	25.20	gene:FBgn0011747 transcript:FBtr0089171	[more]
Ank	5.141e-25	25.20	gene:FBgn0011747 transcript:FBtr0089173	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1b	1.241e-29	26.95	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	1.338e-29	26.95	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	6.252e-29	27.17	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1b	6.267e-29	27.17	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
BX640476.1	2.244e-28	26.77	ankyrin 1, erythrocytic b [Source:NCBI gene;Acc:79...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dapk1	1.611e-26	25.62	death associated protein kinase 1 [Source:NCBI gen...	[more]
pan3	1.966e-26	25.66	poly(A) specific ribonuclease subunit PAN3 [Source...	[more]
senp1	3.975e-24	25.67	SUMO specific peptidase 1 [Source:Xenbase;Acc:XB-G...	[more]
ANK1	7.461e-23	22.50	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]
ANK1	7.561e-23	22.50	ankyrin 1 [Source:NCBI gene;Acc:613080]	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ank2	2.410e-26	25.43	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	6.719e-25	22.52	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	3.625e-24	22.05	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	4.371e-24	25.76	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]
Ank2	4.844e-24	25.76	ankyrin 2, brain [Source:MGI Symbol;Acc:MGI:88025]	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P16157\|ANK1_HUMAN	2.412e-24	23.70	Ankyrin-1 OS=Homo sapiens OX=9606 GN=ANK1 PE=1 SV=...	[more]
sp\|Q502K3\|ANR52_DANRE	6.738e-24	25.45	Serine/threonine-protein phosphatase 6 regulatory ...	[more]
sp\|Q8UVC3\|INVS_CHICK	5.529e-23	27.63	Inversin OS=Gallus gallus OX=9031 GN=INVS PE=2 SV=...	[more]
sp\|P53355\|DAPK1_HUMAN	7.724e-23	24.62	Death-associated protein kinase 1 OS=Homo sapiens ...	[more]
sp\|G5E8K5\|ANK3_MOUSE	1.036e-22	23.34	Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q16FI9	1.907e-40	32.50	AAEL014742-PA (Fragment) OS=Aedes aegypti OX=7159 ...	[more]
J9HSB7	9.128e-38	29.02	AAEL017480-PA (Fragment) OS=Aedes aegypti OX=7159 ...	[more]
A0A1X7T5X6	5.016e-37	34.83	Uncharacterized protein OS=Amphimedon queenslandic...	[more]
Q16FR1	7.761e-37	30.68	AAEL014668-PA (Fragment) OS=Aedes aegypti OX=7159 ...	[more]
A0A182GGY8	7.727e-36	31.60	ANK_REP_REGION domain-containing protein OS=Aedes ...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ank1b	1.229e-26	27.27	ankyrin 1, erythrocytic b [Source:ZFIN;Acc:ZDB-GEN...	[more]
ank1a	4.216e-26	26.88	ankyrin 1, erythrocytic a [Source:ZFIN;Acc:ZDB-GEN...	[more]
ENSAMXT00000037173.1	7.841e-26	22.36	pep primary_assembly:Astyanax_mexicanus-2.0:16:210...	[more]
ENSAMXT00000048191.1	4.240e-23	24.31	pep primary_assembly:Astyanax_mexicanus-2.0:15:310...	[more]
dapk1	2.193e-22	24.32	death-associated protein kinase 1 [Source:ZFIN;Acc...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000095.1	2.635e-25	22.40	pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 g...	[more]
ENSPMAT00000000093.1	3.322e-25	26.46	pep scaffold:Pmarinus_7.0:GL477582:20502:66045:1 g...	[more]
ENSPMAT00000007449.1	8.257e-22	20.63	pep scaffold:Pmarinus_7.0:GL478728:201453:233342:1...	[more]
ENSPMAT00000007446.1	1.906e-20	24.02	pep scaffold:Pmarinus_7.0:GL478728:200023:240674:1...	[more]
ENSPMAT00000007954.1	1.423e-19	21.61	pep scaffold:Pmarinus_7.0:GL479092:583:36301:1 gen...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
HOS4	4.830e-9	28.85	Subunit of the Set3 complex; complex is a meiotic-...	[more]
AVO2	5.098e-9	29.03	Component of a complex containing the Tor2p kinase...	[more]
GDE1	5.316e-9	23.88	Glycerophosphocholine (GroPCho) phosphodiesterase;...	[more]
PHO81	8.283e-9	23.18	Cyclin-dependent kinase (CDK) inhibitor; regulates...	[more]
NAS6	4.602e-8	25.87	Evolutionarily conserved 19S regulatory particle a...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO38702	1.448e-17	30.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49485	1.062e-14	25.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43690	1.078e-14	25.20	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28178	4.995e-14	28.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43381	2.155e-13	30.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dapk1	7.997e-28	25.08	death associated protein kinase 1 [Source:NCBI gen...	[more]
dapk1	1.050e-27	25.08	death associated protein kinase 1 [Source:NCBI gen...	[more]
dapk1	1.101e-27	25.08	death associated protein kinase 1 [Source:NCBI gen...	[more]
ENSORLT00000040233.1	1.381e-26	24.74	pep primary_assembly:ASM223467v1:19:16412534:16434...	[more]
ank1a	1.195e-25	25.71	ankyrin-1 [Source:NCBI gene;Acc:101174837]	[more]

BLAST of Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000021295.1	0.000e+0	100.00	SMESG000021295.1	[more]
SMESG000040665.1	2.813e-59	38.20	SMESG000040665.1	[more]
SMESG000040665.1	5.756e-59	38.20	SMESG000040665.1	[more]
SMESG000040665.1	8.069e-59	38.20	SMESG000040665.1	[more]
SMESG000040665.1	1.439e-58	38.20	SMESG000040665.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30002042 ID=SMED30002042|Name=Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase|organism=Schmidtea mediterranea sexual|type=transcript|length=1310bp
TTTTACTATGTAATTGATTGACATTGAATTGTTCAGCATCGCACTAGATT
TAAATTTCAAATTACCTTTTGAATGGAAGTTGTCAAAAAAAATAATAATT
TGGGTGTATTTGAAAAAGTTGTCAAGTCCGGAAACGTGATGGAAGTCAAA
AAGCGTCTCAAAAAAGAATTTCTCCATTCAGATTTTAATCCTTTTACTCA
GTGTCAAGCTATCCATGTAGCATGCAAGCAAGGATTTGTGGAGGTTGTCA
AGATTTTAATAAACAAAAAATGCAATATAGAACAGGAAATGATTTGGAAT
ATCAAGCCGGTCCACATCACCTGCCTGGTGGGAAACATTGAAATTCTGAG
ACTCCTTATCGCTTATCGATGCGACTTAGAAAGTATAGCAAATATTCCAA
CAGATGAAAATTTCGAGAAATTATTTGACATTGATTCAGAGAACTCCGAG
TCGATTAGCACTATGAAAACTGTGCAAACCCGCCCGATTCACATAGCATG
CTGGAAAGGACATTGTAACATTGTAAAATTGATGATAGATAACGACTGCA
ACTTACAGACCAATGATAAAGATAACTGGAAACCAATTCACGTGGCGTGC
GTATATGGGCACGTTGATATTTTAAAATTGTTATTGGAAAATAATTGCAC
CACAGAAACTGAAGATAAATACAAAACGAGACCGATCCATTATGCGTGCA
AAACTGGCCATGTGGAAATTGTGAGAATTCTCGTTGAAAACAATTGCAAC
TTCGAAAGTCAGAATATTGAGAAAAGACGTCCGATTCATTATGCGTGTAA
AAGTGGACATGTGGACATTGTAAAGTTCCTCATTCACAATAAATGCAATC
TTGAGGTTGAAGATATTGATGGTAAAACACCATTAGACTTAGCATTAGAA
AACAATAATGAAATTTGCGTTGATATGATACTCACAGAAATCGAAGCAAG
GAAAAAGAAAATCTCAGAAATGAGACAAGCTTTCGTTGACGCTCCACGAC
CAGGACCTTCCACAAAAGAGAGAATGAAAGTAACTGTCAAAGCAAGAATC
GAAACAAAGCCAGAAAGAAATATTTGCAAAATTTGTTACGATCGAGAAGT
CGACTGCGTGTTGAGCTGTGGACATGTCTTCTGTATGTTATGTGGGAAAA
GGTTTTCCATCTGTCCAGTCTGTAGAACTAAATCCACAAATCACATCAGA
ATGTTTTTAGATTAATTTCTTAAACAATGAAAATATTTAATATTGTTAAT
AATAATAATAATTTTATAGTCAAAATTGGTTGAATTTCATCTATGTAAAT
TAAGCATAGT

protein sequence of SMED30002042-orf-1

>SMED30002042-orf-1 ID=SMED30002042-orf-1|Name=SMED30002042-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=381bp
MEVVKKNNNLGVFEKVVKSGNVMEVKKRLKKEFLHSDFNPFTQCQAIHVA
CKQGFVEVVKILINKKCNIEQEMIWNIKPVHITCLVGNIEILRLLIAYRC
DLESIANIPTDENFEKLFDIDSENSESISTMKTVQTRPIHIACWKGHCNI
VKLMIDNDCNLQTNDKDNWKPIHVACVYGHVDILKLLLENNCTTETEDKY
KTRPIHYACKTGHVEIVRILVENNCNFESQNIEKRRPIHYACKSGHVDIV
KFLIHNKCNLEVEDIDGKTPLDLALENNNEICVDMILTEIEARKKKISEM
RQAFVDAPRPGPSTKERMKVTVKARIETKPERNICKICYDREVDCVLSCG
HVFCMLCGKRFSICPVCRTKSTNHIRMFLD*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0014731	spectrin-associated cytoskeleton
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0016529	sarcoplasmic reticulum
GO:0030018	Z disc
GO:0030673	axolemma
GO:0031430	M band
GO:0031672	A band
GO:0042383	sarcolemma
GO:0043005	neuron projection
GO:0045211	postsynaptic membrane

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0005198	structural molecule activity
GO:0005200	structural constituent of cytoskeleton
GO:0008093	cytoskeletal adaptor activity
GO:0019899	enzyme binding
GO:0030507	spectrin binding
GO:0051117	ATPase binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR001841	Znf_RING
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom
IPR013083	Znf_RING/FYVE/PHD

Vocabulary: **biological process**
Term	Definition
GO:0006887	exocytosis
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0007010	cytoskeleton organization
GO:0007165	signal transduction
GO:0010638	positive regulation of organelle organization
GO:0045199	maintenance of epithelial cell apical/basal polarity
GO:0072661	protein targeting to plasma membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001841	Zinc finger, RING-type	SMART	SM00184	ring_2	coord: 335..367 e-value: 0.0039 score: 26.4
IPR001841	Zinc finger, RING-type	PROSITE	PS50089	ZF_RING_2	coord: 335..368 score: 12.061
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 200..229 e-value: 0.013 score: 24.7 coord: 42..71 e-value: 0.05 score: 22.7 coord: 75..104 e-value: 69.0 score: 12.3 coord: 233..262 e-value: 8.6E-4 score: 28.6 coord: 167..196 e-value: 0.037 score: 23.2 coord: 134..163 e-value: 44.0 score: 13.0 coord: 266..295 e-value: 18.0 score: 14.3
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 134..166 score: 8.63
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 167..199 score: 10.579
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 233..265 score: 10.686
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 200..232 score: 10.072
None	No IPR available	PFAM	PF13637	Ank_4	coord: 235..285 e-value: 3.0E-8 score: 34.0
None	No IPR available	PFAM	PF13920	zf-C3HC4_3	coord: 332..371 e-value: 6.7E-7 score: 29.1
None	No IPR available	PANTHER	PTHR24193:SF76	GA-BINDING PROTEIN SUBUNIT BETA-1	coord: 194..287
None	No IPR available	PANTHER	PTHR24193:SF76	GA-BINDING PROTEIN SUBUNIT BETA-1	coord: 122..199
None	No IPR available	PANTHER	PTHR24193	ANKYRIN REPEAT PROTEIN	coord: 194..287
None	No IPR available	PANTHER	PTHR24193	ANKYRIN REPEAT PROTEIN	coord: 162..280
None	No IPR available	PANTHER	PTHR24193	ANKYRIN REPEAT PROTEIN	coord: 122..199
None	No IPR available	PANTHER	PTHR24193:SF76	GA-BINDING PROTEIN SUBUNIT BETA-1	coord: 162..280
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 331..373
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 311..380 e-value: 1.3E-12 score: 49.0
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 110..304 e-value: 1.6E-47 score: 163.5
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 3..109 e-value: 6.4E-11 score: 44.0
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 16..287
IPR020683	Ankyrin repeat-containing domain	PFAM	PF12796	Ank_2	coord: 139..230 e-value: 1.5E-17 score: 63.9
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 42..287 score: 44.325