PHD-type domain-containing protein

Overview
NamePHD-type domain-containing protein
Smed IDSMED30002037
Length (bp)1558
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PHD-type domain-containing protein (SMED30002037) t-SNE clustered cells

Violin plots show distribution of expression levels for PHD-type domain-containing protein (SMED30002037) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PHD-type domain-containing protein (SMED30002037) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PHD-type domain-containing protein (SMED30002037) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30002037

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30002037SMESG000018860.1 SmedASXL_016277SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: TCF20 (transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631])

HSP 1 Score: 76.6406 bits (187), Expect = 4.501e-15
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK K
Sbjct:  152 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKNK 236
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: TCF20 (transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631])

HSP 1 Score: 76.6406 bits (187), Expect = 4.501e-15
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK K
Sbjct:  152 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKNK 236
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: TCF20 (transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631])

HSP 1 Score: 76.6406 bits (187), Expect = 4.501e-15
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK K
Sbjct:  152 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKNK 236
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: TCF20 (transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631])

HSP 1 Score: 76.6406 bits (187), Expect = 4.501e-15
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK K
Sbjct:  152 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKNK 236
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Match: TCF20 (transcription factor 20 [Source:HGNC Symbol;Acc:HGNC:11631])

HSP 1 Score: 76.6406 bits (187), Expect = 4.501e-15
Identity = 38/86 (44.19%), Postives = 50/86 (58.14%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK K
Sbjct:  152 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKNK 236
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: F01D4.5 (pep chromosome:WBcel235:IV:10482635:10483594:-1 gene:WBGene00008488.1 transcript:F01D4.5b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F01D4.5)

HSP 1 Score: 56.225 bits (134), Expect = 5.358e-9
Identity = 29/81 (35.80%), Postives = 47/81 (58.02%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCN 1453
            E+WFH  C+LWAP  +L G+ ++  L+  + +  +  C VC K GA ++   K  +   HY CA + G KL++   ++LCN
Sbjct:  113 ELWFHGSCVLWAPNVHLHGN-QLTNLDNQIDIFWSQTCIVCRKTGAAISVQNKK-NTFIHYPCAKNKGYKLDEH--ALLCN 189
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: F01D4.5 (pep chromosome:WBcel235:IV:10482629:10483655:-1 gene:WBGene00008488.1 transcript:F01D4.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F01D4.5)

HSP 1 Score: 56.225 bits (134), Expect = 5.358e-9
Identity = 29/81 (35.80%), Postives = 47/81 (58.02%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCN 1453
            E+WFH  C+LWAP  +L G+ ++  L+  + +  +  C VC K GA ++   K  +   HY CA + G KL++   ++LCN
Sbjct:  113 ELWFHGSCVLWAPNVHLHGN-QLTNLDNQIDIFWSQTCIVCRKTGAAISVQNKK-NTFIHYPCAKNKGYKLDEH--ALLCN 189
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Match: F01D4.5 (pep chromosome:WBcel235:IV:10482686:10483655:-1 gene:WBGene00008488.1 transcript:F01D4.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F01D4.5)

HSP 1 Score: 49.6766 bits (117), Expect = 1.607e-6
Identity = 23/64 (35.94%), Postives = 36/64 (56.25%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCA 1402
            E+WFH  C+LWAP  +L G+ ++  L+  + +  +  C VC K GA ++   K  +   HY CA
Sbjct:  154 ELWFHGSCVLWAPNVHLHGN-QLTNLDNQIDIFWSQTCIVCRKTGAAISVQNKK-NTFIHYPCA 215
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: trr (gene:FBgn0023518 transcript:FBtr0070363)

HSP 1 Score: 54.299 bits (129), Expect = 2.581e-7
Identity = 21/70 (30.00%), Postives = 34/70 (48.57%), Query Frame = 2 
Query: 1196 ITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAV 1405
            + +D + W H  C LW+   Y    G +   + AL+  L+  C  CH+ GA + C    C+  +H  CA+
Sbjct: 1916 LNFDVDKWVHLNCALWSNGVYETVSGALMNFQTALQAGLSQACSACHQPGATIKCFKSRCNSLYHLPCAI 1985
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: trx (gene:FBgn0003862 transcript:FBtr0082947)

HSP 1 Score: 54.299 bits (129), Expect = 2.595e-7
Identity = 26/93 (27.96%), Postives = 46/93 (49.46%), Query Frame = 2 
Query: 1184 EDYRITWDG-EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            E+ R+ + G + W H  C +W+   +   DG +  +  A+      +C VC   GA + C  ++C +++HY CA S+      ++ SM C  H
Sbjct: 1750 EEARLLYCGHDCWVHTNCAMWSAEVFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLTDK-SMYCPAH 1841
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: trx (gene:FBgn0003862 transcript:FBtr0082950)

HSP 1 Score: 54.299 bits (129), Expect = 2.595e-7
Identity = 26/93 (27.96%), Postives = 46/93 (49.46%), Query Frame = 2 
Query: 1184 EDYRITWDG-EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            E+ R+ + G + W H  C +W+   +   DG +  +  A+      +C VC   GA + C  ++C +++HY CA S+      ++ SM C  H
Sbjct: 1750 EEARLLYCGHDCWVHTNCAMWSAEVFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLTDK-SMYCPAH 1841
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: trr (gene:FBgn0023518 transcript:FBtr0070362)

HSP 1 Score: 54.299 bits (129), Expect = 2.623e-7
Identity = 21/70 (30.00%), Postives = 34/70 (48.57%), Query Frame = 2 
Query: 1196 ITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAV 1405
            + +D + W H  C LW+   Y    G +   + AL+  L+  C  CH+ GA + C    C+  +H  CA+
Sbjct: 1895 LNFDVDKWVHLNCALWSNGVYETVSGALMNFQTALQAGLSQACSACHQPGATIKCFKSRCNSLYHLPCAI 1964
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Match: trx (gene:FBgn0003862 transcript:FBtr0082948)

HSP 1 Score: 54.299 bits (129), Expect = 2.857e-7
Identity = 26/93 (27.96%), Postives = 46/93 (49.46%), Query Frame = 2 
Query: 1184 EDYRITWDG-EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            E+ R+ + G + W H  C +W+   +   DG +  +  A+      +C VC   GA + C  ++C +++HY CA S+      ++ SM C  H
Sbjct: 1382 EEARLLYCGHDCWVHTNCAMWSAEVFEEIDGSLQNVHSAVARGRMIKCTVCGNRGATVGCNVRSCGEHYHYPCARSIDCAFLTDK-SMYCPAH 1473
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-94l16.4 (si:dkey-94l16.4 [Source:ZFIN;Acc:ZDB-GENE-121214-291])

HSP 1 Score: 103.99 bits (258), Expect = 5.474e-23
Identity = 60/184 (32.61%), Postives = 92/184 (50.00%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGL-PLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKM----VIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +C  CG +S  + LG+L+GPY+ +     G  P + +  +  E +N  S     GK+A + +    L      V + ++ VR  +     S       + E WFH +C +W+   +L   GK+ GLE A+K+A  + C  C + GA L C  K C   +HY CAV  G  LN++ +SM C KHK
Sbjct:  546 VCCLCGSSSNAMDLGDLHGPYYAE-----GFKPASKVASNHQEDENSDSDSSFRGKTAAEGNWTDSLDWRWSGVGEPARRVRTDSPIDWYSPPVVPLHETEHWFHEDCAIWSAGVFLV-RGKLYGLENAVKLAKVSVCSTCQRTGATLGCVYKGCLNKYHYTCAVQSGCVLNEDNYSMKCRKHK 723
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-165g14.1 (si:ch211-165g14.1 [Source:ZFIN;Acc:ZDB-GENE-131127-601])

HSP 1 Score: 100.523 bits (249), Expect = 5.991e-22
Identity = 60/194 (30.93%), Postives = 88/194 (45.36%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENI-----SGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEKW*QISNIR 1492
             C  CG T     LG+L+GPY     +      S LPL      D    +    +   G    +  K  G + + +S                      GE W H +C +W    +L   GK+ GLEEA+++A  + C  C+++GA L C  K+C + +H+ CAV  GS LN+E F+M C KHK K  ++S  R
Sbjct:  495 FCCLCGSTGNVEGLGDLHGPYHRSGAHPVCKVDSSLPLALKQEPDCSDVDSLDSLEDGGSQVKRRRKENGCESLEESGAP-------------------GEHWIHEDCSIWTAGVFLV-KGKLYGLEEAIRLAQESVCSFCNRVGATLGCFFKDCPQKYHFPCAVQSGSALNEENFTMRCPKHKNKVSRMSVSR 668
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: tcf20 (transcription factor 20 [Source:ZFIN;Acc:ZDB-GENE-110411-97])

HSP 1 Score: 80.1073 bits (196), Expect = 1.158e-16
Identity = 59/221 (26.70%), Postives = 97/221 (43.89%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSV----VGASGKSAIKTD----------------KNGGLKMVIQSSKSV-RNSTVKKSASEDYR--------------------ITWDGE-VWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +C  C K + +  LG+LYGP++   E  + LP        N+   +Q++      A+G ++I T+                 +   K   +SS+ + R   +   AS  ++                    +  D E +W H  C++W    YL  +G++ GL+EAL  A +A C  C   G+ L C +K C   +HY CA+     LN++ FS+ C KHK
Sbjct:    5 LCCLCQKWANYKHLGDLYGPFY-PAEYAAKLP-------KNQPQVRQTLSHFGPAATGMTSIPTELQVESSQQRPQHRKLTSHPRFKRRHKSSEDLPRTVPINSKASLPFQPPPPSLDALGPMAQLAQLPLVPLDPEELWVHESCMVWTSGIYLV-NGRLYGLQEALDGARDASCSHCEMAGSTLGCYSKGCTLRYHYICAIDADCSLNEDNFSLRCPKHK 216
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: tcf20 (transcription factor 20 [Source:ZFIN;Acc:ZDB-GENE-110411-97])

HSP 1 Score: 76.6406 bits (187), Expect = 4.335e-14
Identity = 34/84 (40.48%), Postives = 49/84 (58.33%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E+W H  C++W    YL  +G++ GL+EAL  A +A C  C   G+ L C +K C   +HY CA+     LN++ FS+ C KHK
Sbjct: 2254 ELWVHESCMVWTSGIYLV-NGRLYGLQEALDGARDASCSHCEMAGSTLGCYSKGCTLRYHYICAIDADCSLNEDNFSLRCPKHK 2336
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Match: rai1 (retinoic acid induced 1 [Source:ZFIN;Acc:ZDB-GENE-101203-2])

HSP 1 Score: 68.1662 bits (165), Expect = 1.731e-11
Identity = 34/85 (40.00%), Postives = 47/85 (55.29%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKE 1465
            E W H  C +W     L  D K+ GL EA++ A +A+C  C   GA + C  K+C +++HY CA   G    +E FS+ C KHKE
Sbjct: 1851 EHWAHEACAVWTTGIVLVAD-KLFGLTEAVQKAAHAKCSGCQGEGASVCCGWKSCTQSYHYICAKESGCTFEEETFSIRCPKHKE 1934
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: ltbp3 (latent transforming growth factor beta binding protein 3 [Source:Xenbase;Acc:XB-GENE-6050660])

HSP 1 Score: 77.0258 bits (188), Expect = 4.341e-14
Identity = 56/211 (26.54%), Postives = 87/211 (41.23%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYF-IDT-ENISGLPL-------------------TCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMV-----------IQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +C  C   + F  LG+L GPY+ +D+  N  G P                     C   S     +    +  S  + ++T   G L+ +           I  ++  R     K+           E W H  C +W    YL   GK+ G+ EA++MA    C  C + GA + C+ K C++++H  CAV  G  L++E FS+ C KHK
Sbjct: 1607 VCCLCRNPANFKDLGDLCGPYYPMDSLPNKKGRPKDKFRIAEAPAEKAAKVSDSVCTVGSGRAPCSDVGELDPSKHNNLRTSARGMLRKLPSCYCCSKTVEIAETEKPRRHQCNKALEPPTPELETQEHWVHEACAVWTSGVYLVA-GKLYGINEAIQMAAAGLCPKCQRPGATVGCSHKGCEQSYHITCAVEAGCLLSEENFSLRCPKHK 1816
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: ltbp3 (latent transforming growth factor beta binding protein 3 [Source:Xenbase;Acc:XB-GENE-6050660])

HSP 1 Score: 77.0258 bits (188), Expect = 4.409e-14
Identity = 56/212 (26.42%), Postives = 88/212 (41.51%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYF-IDT-ENISGLPL-------------------TCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMV-----------IQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKE 1465
            +C  C   + F  LG+L GPY+ +D+  N  G P                     C   S     +    +  S  + ++T   G L+ +           I  ++  R     K+           E W H  C +W    YL   GK+ G+ EA++MA    C  C + GA + C+ K C++++H  CAV  G  L++E FS+ C KHK+
Sbjct: 1607 VCCLCRNPANFKDLGDLCGPYYPMDSLPNKKGRPKDKFRIAEAPAEKAAKVSDSVCTVGSGRAPCSDVGELDPSKHNNLRTSARGMLRKLPSCYCCSKTVEIAETEKPRRHQCNKALEPPTPELETQEHWVHEACAVWTSGVYLVA-GKLYGINEAIQMAAAGLCPKCQRPGATVGCSHKGCEQSYHITCAVEAGCLLSEENFSLRCPKHKK 1817
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: TCF20 (transcription factor 20 (AR1) [Source:NCBI gene;Acc:100038081])

HSP 1 Score: 72.0182 bits (175), Expect = 1.597e-12
Identity = 59/228 (25.88%), Postives = 91/228 (39.91%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTV-----KKSASED----------YRITWD--------------------------------GEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            +C  CGK + +  LG+L+GP++ + E  S L         +E   +  V         K+D +   +   Q ++  R+ T      +++ S D          +R T D                                 E W H  C+LWA   Y    G++ GL EA+ +A   +C  C + GA L C  K C   +H+ CA+     LN+E FS+ C KHK K
Sbjct: 1611 VCCLCGKWANYRNLGDLFGPFY-NQEYASTLSKNPPPKKSSETPRKVKVRHKDTSDGSKSDSDEEEEEEPQQAREQRSLTAHPRYKRRNRSGDCTSSRLTVPSHRKTTDPSELTPMDSSGPSTAEAGPEQGVQIPQLPLDSNEFWMHEGCVLWANGVYFVC-GRLYGLREAVDIAREMKCSHCQETGATLGCYNKGCACCYHFPCAMDSECLLNEENFSVRCPKHKTK 1836
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: TCF20 (transcription factor 20 (AR1) [Source:NCBI gene;Acc:100038081])

HSP 1 Score: 71.633 bits (174), Expect = 1.970e-12
Identity = 60/228 (26.32%), Postives = 90/228 (39.47%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTV-----KKSASED----------YRITWD--------------------------------GEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            +C  CGK + +  LG+L+GP F + E  S L         +E   +  V         K+D +   +   Q ++  R+ T      +++ S D          +R T D                                 E W H  C+LWA   Y    G++ GL EA+ +A   +C  C + GA L C  K C   +H+ CA+     LN+E FS+ C KHK K
Sbjct: 1632 VCCLCGKWANYRNLGDLFGP-FYNQEYASTLSKNPPPKKSSETPRKVKVRHKDTSDGSKSDSDEEEEEEPQQAREQRSLTAHPRYKRRNRSGDCTSSRLTVPSHRKTTDPSELTPMDSSGPSTAEAGPEQGVQIPQLPLDSNEFWMHEGCVLWANGVYFVC-GRLYGLREAVDIAREMKCSHCQETGATLGCYNKGCACCYHFPCAMDSECLLNEENFSVRCPKHKTK 1857
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Match: TCF20 (transcription factor 20 (AR1) [Source:NCBI gene;Acc:100038081])

HSP 1 Score: 71.2478 bits (173), Expect = 3.215e-12
Identity = 60/228 (26.32%), Postives = 90/228 (39.47%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTV-----KKSASED----------YRITWD--------------------------------GEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            +C  CGK + +  LG+L+GP F + E  S L         +E   +  V         K+D +   +   Q ++  R+ T      +++ S D          +R T D                                 E W H  C+LWA   Y    G++ GL EA+ +A   +C  C + GA L C  K C   +H+ CA+     LN+E FS+ C KHK K
Sbjct: 1611 VCCLCGKWANYRNLGDLFGP-FYNQEYASTLSKNPPPKKSSETPRKVKVRHKDTSDGSKSDSDEEEEEEPQQAREQRSLTAHPRYKRRNRSGDCTSSRLTVPSHRKTTDPSELTPMDSSGPSTAEAGPEQGVQIPQLPLDSNEFWMHEGCVLWANGVYFVC-GRLYGLREAVDIAREMKCSHCQETGATLGCYNKGCACCYHFPCAMDSECLLNEENFSVRCPKHKVK 1836
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Zfp957 (zinc finger protein 957 [Source:MGI Symbol;Acc:MGI:2145729])

HSP 1 Score: 82.4185 bits (202), Expect = 3.633e-16
Identity = 40/84 (47.62%), Postives = 49/84 (58.33%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E W H +CILWA  TYL   G++ GL EAL+ A +  C  C K GA L C  K C   +HY CA+     LN+E FS+ C KHK
Sbjct:  472 EFWVHEDCILWANGTYLV-YGRLYGLLEALENARDVTCSHCQKAGATLGCYNKGCTFRYHYPCAIDADCLLNEENFSVRCPKHK 554
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Zfp957 (zinc finger protein 957 [Source:MGI Symbol;Acc:MGI:2145729])

HSP 1 Score: 82.4185 bits (202), Expect = 3.633e-16
Identity = 40/84 (47.62%), Postives = 49/84 (58.33%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E W H +CILWA  TYL   G++ GL EAL+ A +  C  C K GA L C  K C   +HY CA+     LN+E FS+ C KHK
Sbjct:  472 EFWVHEDCILWANGTYLV-YGRLYGLLEALENARDVTCSHCQKAGATLGCYNKGCTFRYHYPCAIDADCLLNEENFSVRCPKHK 554
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Rai1 (retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI:103291])

HSP 1 Score: 78.1814 bits (191), Expect = 1.339e-14
Identity = 42/115 (36.52%), Postives = 64/115 (55.65%), Query Frame = 2 
Query: 1118 GLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            G + V Q+ KS ++   K++ +E    T   E W H  C +W    YL   GK+ GL+EA+K+A++  C  CH+ GA ++C+ K C   +HY CA   G    +E F++ C KHK
Sbjct: 1774 GGEEVAQADKSRKHECSKEAPTEPGGDT--QEHWVHEACAVWTSGVYLVA-GKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHK 1885
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Rai1 (retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI:103291])

HSP 1 Score: 78.1814 bits (191), Expect = 1.339e-14
Identity = 42/115 (36.52%), Postives = 64/115 (55.65%), Query Frame = 2 
Query: 1118 GLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            G + V Q+ KS ++   K++ +E    T   E W H  C +W    YL   GK+ GL+EA+K+A++  C  CH+ GA ++C+ K C   +HY CA   G    +E F++ C KHK
Sbjct: 1774 GGEEVAQADKSRKHECSKEAPTEPGGDT--QEHWVHEACAVWTSGVYLVA-GKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHK 1885
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Match: Rai1 (retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI:103291])

HSP 1 Score: 78.1814 bits (191), Expect = 1.339e-14
Identity = 42/115 (36.52%), Postives = 64/115 (55.65%), Query Frame = 2 
Query: 1118 GLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            G + V Q+ KS ++   K++ +E    T   E W H  C +W    YL   GK+ GL+EA+K+A++  C  CH+ GA ++C+ K C   +HY CA   G    +E F++ C KHK
Sbjct: 1774 GGEEVAQADKSRKHECSKEAPTEPGGDT--QEHWVHEACAVWTSGVYLVA-GKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHK 1885
[Close]
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q61818|RAI1_MOUSE (Retinoic acid-induced protein 1 OS=Mus musculus OX=10090 GN=Rai1 PE=1 SV=3)

HSP 1 Score: 78.1814 bits (191), Expect = 9.369e-14
Identity = 42/115 (36.52%), Postives = 64/115 (55.65%), Query Frame = 2 
Query: 1118 GLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            G + V Q+ KS ++   K++ +E    T   E W H  C +W    YL   GK+ GL+EA+K+A++  C  CH+ GA ++C+ K C   +HY CA   G    +E F++ C KHK
Sbjct: 1774 GGEEVAQADKSRKHECSKEAPTEPGGDT--QEHWVHEACAVWTSGVYLVA-GKLFGLQEAMKVAVDMPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEENFTLKCPKHK 1885
[Close]
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9EPQ8|TCF20_MOUSE (Transcription factor 20 OS=Mus musculus OX=10090 GN=Tcf20 PE=1 SV=3)

HSP 1 Score: 77.7962 bits (190), Expect = 1.206e-13
Identity = 37/84 (44.05%), Postives = 49/84 (58.33%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK
Sbjct: 1878 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHK 1960
[Close]
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UGU0|TCF20_HUMAN (Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3)

HSP 1 Score: 77.7962 bits (190), Expect = 1.347e-13
Identity = 37/84 (44.05%), Postives = 49/84 (58.33%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E W H  CILWA   YL   G++ GL+EAL++A   +C  C + GA L C  K C   +HY CA+     L++E FS+ C KHK
Sbjct: 1851 EFWVHEGCILWANGIYLVC-GRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHK 1933
[Close]
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7Z5J4|RAI1_HUMAN (Retinoic acid-induced protein 1 OS=Homo sapiens OX=9606 GN=RAI1 PE=1 SV=2)

HSP 1 Score: 71.633 bits (174), Expect = 1.181e-11
Identity = 34/84 (40.48%), Postives = 46/84 (54.76%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            E W H  C +W    YL   GK+ GL+EA+K+A++  C  C + GA + C  K C   +HY CA   G    +E FS+ C KHK
Sbjct: 1821 EHWVHEACAVWTGGVYLVA-GKLFGLQEAMKVAVDMMCSSCQEAGATIGCCHKGCLHTYHYPCASDAGCIFIEENFSLKCPKHK 1903
[Close]
BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NEZ4|KMT2C_HUMAN (Histone-lysine N-methyltransferase 2C OS=Homo sapiens OX=9606 GN=KMT2C PE=1 SV=3)

HSP 1 Score: 58.9214 bits (141), Expect = 1.020e-7
Identity = 29/88 (32.95%), Postives = 43/88 (48.86%), Query Frame = 2 
Query: 1205 DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            D ++W H  C LW+   Y    G +  +E AL+  L  +C  CHK GA   C    C   +H+ CA+       +++ +MLC  HK K
Sbjct: 4423 DLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDK-TMLCPMHKPK 4509
[Close]
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A5J4NCJ8 (PHD-type domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0007888 PE=4 SV=1)

HSP 1 Score: 157.147 bits (396), Expect = 1.171e-40
Identity = 88/249 (35.34%), Postives = 141/249 (56.63%), Query Frame = 2 
Query:  818 IINPALRGNGEYQLSSVYRP-----NLKSVCNNQISNTHPCICAFCGKTSEFLQLGNLYGPYFI-DTENISGLPLT-CMFP----------------SDNEQDNQQSVVGA----SGKSAIKTDKN-----GGLKMVIQS--SKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            + N  +  N  Y+  S YRP     N  S+  ++I+   P +CAFCG+ + F+ LG+LYGPY+I D E +   P T C+ P                S  E+  + +  G       +SA    +N     G L+++I+S  + +   S+ K++++E  R+  +GEVWFHREC+LWAP T+++G+G +  L EAL+++LN  C  C K GAIL+C ++ C+ ++HY CA      LN+EQ++++C KHK
Sbjct:   11 LCNSTVNANRPYRRLS-YRPVIQRKNPSSLQQSEITTDQPWLCAFCGRDNTFVNLGSLYGPYWITDAERLQLPPETVCLAPPVSQTSSSPVRCSKSVSSGERSGRSARSGVITSTVTRSAAAQGRNSVANTGSLRLIIKSRNASASSQSSTKQASNEPARVGLNGEVWFHRECVLWAPGTFIQGNGTVESLGEALQLSLNTVCSHCDKRGAILSCCSRGCNLSYHYQCARDAECHLNEEQYTLMCKKHK 258
[Close]
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A074ZUB2 (PHD-type domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_02628 PE=4 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 3.792e-38
Identity = 79/206 (38.35%), Postives = 119/206 (57.77%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFP------------SDNEQDNQQ-----------SVVGASGKSAIK----TDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +CAFCGK + FL+LG+LYGPY++     + LP   + P            SD   + ++           S V  SG +A +      K G L++VI++  +    +  K A++ +RI   GEVWFH EC+LWAP T ++G+G + GL EAL+++L   C  C K GAIL+C ++ CD ++HYYCA   G KLN EQ++++C KH+
Sbjct:  553 LCAFCGKDNSFLELGSLYGPYWVAEAECAQLPTEMVAPKELPFANGPSKPSDTNSNVERLSRRARSGVVTSAVTRSGATASQGQPTVSKTGALRLVIKARTNRTAQSATKPAADLFRIGPTGEVWFHLECVLWAPGTCIQGNGTVTGLGEALQLSLGTLCSHCDKPGAILSCCSRGCDLSYHYYCARLAGCKLNDEQYTIMCKKHQ 758
[Close]
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A4S2M4P1 (PHD-type domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002738 PE=4 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 1.736e-37
Identity = 79/206 (38.35%), Postives = 118/206 (57.28%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFP------------SDNEQDNQQ-----------SVVGASGKSAIK----TDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +CAFCGK + FL+LG+LYGPY++     + LP   + P            SD     ++           S V  SG +A +      K G L++VI++  +       K A++ +RI   GEVWFH EC+LWAP T ++G+G + GL EAL+++L+  C  C K GAIL+C ++ CD ++HYYCA   G KLN EQ++++C KH+
Sbjct:  553 LCAFCGKDNSFLELGSLYGPYWVAETECAQLPTEMVAPKELPFATVQSKPSDTNSSVERLPRRSRSGVVTSTVTRSGAAASQGQPTVSKTGALRLVIKARTNRTAQCAAKPAADLFRIGPTGEVWFHLECVLWAPGTCIQGNGIVTGLGEALQLSLSTLCSHCDKPGAILSCCSRGCDLSYHYYCARLAGCKLNDEQYTIMCKKHQ 758
[Close]
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A504Z173 (Transcription factor 20 OS=Fasciola gigantica OX=46835 GN=FGIG_02242 PE=4 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 6.584e-35
Identity = 78/204 (38.24%), Postives = 114/204 (55.88%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMF-------------PSDNEQDNQQSVVGASG-------KSAIKTDKN-----GGLKMVIQSSKSVRNSTVKKSASE-DYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            +CAFCG+ + FL LG LYGPY++     + +   C+              P  N +  ++     SG       +SA    ++     G L++VI   K+  N TV +  S    RI+ DGEVW H EC LWAP TY+ GDG IGGL EAL+++L+  C  C K GAILNC ++ C+  +HY+CA++   +L+ EQ+++LC KH
Sbjct:  506 LCAFCGEDNNFLSLGGLYGPYYVTASEKAQIIPECVAQLSISPRTPGSHSPGKNSRSGKKGKPAGSGVITSTLTRSAAAQGRSTVANMGALRLVI---KAPNNKTVTEKVSNLRPRISADGEVWVHLECALWAPGTYIVGDGTIGGLGEALQLSLDTICSHCDKRGAILNCCSRGCNLRYHYHCAIAAECQLDHEQYTLLCKKH 706
[Close]
BLAST of PHD-type domain-containing protein vs. TrEMBL
Match: A0A5K3EGI6 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 148.673 bits (374), Expect = 1.166e-34
Identity = 71/177 (40.11%), Postives = 101/177 (57.06%), Query Frame = 2 
Query:  929 CAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            C FCG++  FL+LG +YGPYF+     +  P +       +  +  +    S +S  +T      K  +  S+   +    ++  E  RI  DGEVWFH EC+LWAP TY++GDG IGGL+EA+ MAL A C  C K GAIL+C ++ C   +HY+CA       NQEQF++LC +H
Sbjct:  467 CVFCGESPSFLRLGPIYGPYFVTPSTQARFPPSPSLRLVIKAISPPANGTISVRSVQQTPPPKQQKRRLGKSRKSTDIATAETKVETMRIGRDGEVWFHLECVLWAPGTYIQGDGNIGGLDEAVCMALEASCSHCKKPGAILSCRSRGCGLCYHYHCAHLAECHFNQEQFTVLCKQH 643
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000051866.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000101.1:3022539:3025174:1 gene:ENSAMXG00000037515.1 transcript:ENSAMXT00000051866.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.9669 bits (219), Expect = 1.291e-19
Identity = 59/182 (32.42%), Postives = 92/182 (50.55%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGL-PLTCMFPSDNEQDNQQSVVG--ASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +C  CG+TS  + LG+L+GPY       SG  P +C   +++  +N + V G  +SG +   ++  G  +   +   S +     +S S D R     E W H +C +W+   +L   GK+ GLEEA+++A    C  C   GA L C  K C   +H+ CA+  G   N+E F++ C KHK
Sbjct:   58 LCCLCGRTSNSIGLGDLHGPYCP-----SGYQPDSCQVAANH--NNSELVHGPESSGHNLEVSEVEGPAEQFREQISSDQEPGAPESGS-DCR-----ERWIHEDCSIWSAGIFLI-KGKLYGLEEAVRLAQETVCSCCDTAGATLGCFFKGCPNKYHFPCALQTGCSFNEENFTIRCPKHK 225
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041374.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002300.1:254066:255577:1 gene:ENSAMXG00000043374.1 transcript:ENSAMXT00000041374.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.0922 bits (170), Expect = 1.983e-13
Identity = 34/83 (40.96%), Postives = 47/83 (56.63%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            E+W H  CI+W    YL  +G++ GL+EAL  A +  C  C   G+ L C +K C   +HY CAV     LN++ FS+ C KH
Sbjct:  136 ELWVHESCIVWTSGVYLV-NGRLYGLQEALDGARDTSCSHCEMAGSTLGCYSKGCTLRYHYLCAVE-ACYLNEDNFSLRCPKH 216
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000030243.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000140.1:376738:378240:1 gene:ENSAMXG00000034267.1 transcript:ENSAMXT00000030243.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 2.221e-11
Identity = 46/193 (23.83%), Postives = 75/193 (38.86%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQ---------------------QSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITW---------DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLG 1414
            +C  CG ++  + LG+L+GPY+ +     G       P++ ++  +                     Q+    +G   ++     G      S   +  S   K +  D    W           E W H +C +W+   +    GK+ GLE+A+K+A    C  C K GA L C  K C   +HY CA+  G
Sbjct:   10 VCCLCGGSANAMDLGDLHGPYYPE-----GFKPVSKTPANAQEQREEDSSDSDSSHLVNGNACVVQSQTSWTRNGHHKLRQAAAIGTYQAWSSEGDLSCSPAPKRSRTDSVTDWYSPPIVPLEADEYWLHEDCGIWSAGVFFV-RGKLYGLEKAIKVAQETVCSSCLKTGASLGCFFKGCPNKYHYRCAMHSG 196
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: rai1 (retinoic acid induced 1 [Source:ZFIN;Acc:ZDB-GENE-101203-2])

HSP 1 Score: 67.3958 bits (163), Expect = 2.791e-11
Identity = 57/222 (25.68%), Postives = 87/222 (39.19%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDN--QQSVVGASGKSAIKTDKNGGLKMVIQSSKSV---------RNSTVK-----------------------KSASED------YRITWDGEV---WFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            +C  CGK + + +LG+L GPY+   ++I    L+ M   D  Q+    + +  +     I T +  G K  +Q   S          R + ++                        SA E+       R+  D E    W H  C +W     L   GK+ GL EA + +   +C  C   GA + C  KNC   +HY CA        ++ FS+ C KHK
Sbjct: 1782 VCCLCGKPANYRELGDLCGPYY-PADSIPRKTLSLMHQEDLRQNRNTDKDMATSCSTEQINTPRKDGAKDPLQEGTSEGDCGQPRRERRAQLRTRLGLRMRFRRLQLLQGTTGGAAPSAGEEGSDSALQRLQQDAEAKEHWAHEACAVWTSGVILVS-GKVYGLREAAQDSTVTKCSKCQSEGASIRCQWKNCTHTYHYVCAKE-SCIFEEDTFSIKCPKHK 2000
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Match: kmt2d (lysine methyltransferase 2D [Source:NCBI gene;Acc:103042576])

HSP 1 Score: 60.8474 bits (146), Expect = 3.017e-9
Identity = 28/88 (31.82%), Postives = 43/88 (48.86%), Query Frame = 2 
Query: 1205 DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            D ++W H  C LW+   Y    G +  +E AL+  L   C  C K GA  +C    C   +H+ CA+       +++ +MLC +HK K
Sbjct: 2921 DVDLWVHLNCALWSTEVYETQGGALINVEVALRRGLRTRCACCQKTGATNSCNRLRCPNVYHFACAIRARCMFFKDK-TMLCTQHKLK 3007
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007597.1 (pep scaffold:Pmarinus_7.0:GL478334:30819:39194:1 gene:ENSPMAG00000006860.1 transcript:ENSPMAT00000007597.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 1.821e-15
Identity = 56/241 (23.24%), Postives = 90/241 (37.34%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFI---------------------DTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKM---------------------------VIQSSKSVRNSTVKKSASEDYRITWDG-----------EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEKW 1471
            +C FCG ++ F +LG+L+GPY+                      D E  S        P +  + +     G+S     K  + G                                ++ S   R+   +K A E    T +            E W H+ C +W    +L G G++ GL EA+++A +  C  C + GA L C  K C + +H+ CA+     L ++ F + C KHK  W
Sbjct:  184 VCCFCGFSANFKELGDLFGPYYPQGHAPAARKPQSAPSKDRPSEDAEVASETTRVSEEPEEGHKASPAEPAGSSDHRGTKKPRAGSTDENCASLRGSTRGARCRKPSCYCCVDSDGAVEKSSDGRSRKGRKEAVEKESPTAEAQPPPEVPLDNEEFWVHQPCAVWTSDVFLVG-GRLYGLLEAVEIARDISCSKCQRTGATLGCHGKGCAQRYHFICAMEADCLLCEDNFLIKCAKHKVWW 423
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002322.1 (pep scaffold:Pmarinus_7.0:GL477101:2485:64197:1 gene:ENSPMAG00000002099.1 transcript:ENSPMAT00000002322.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 1.362e-7
Identity = 23/88 (26.14%), Postives = 44/88 (50.00%), Query Frame = 2 
Query: 1205 DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            D ++W H  C LW+   Y    G +  +E A +  L  +C  C ++GA  +C    C   +H+ CA+ +     +++ ++LC  H+ +
Sbjct: 3435 DLDIWVHLNCALWSSEVYETQAGALINVEGARRRGLGTKCGACLRMGATTSCNRPRCPNVYHFACALRMRCMFFKDK-TVLCPAHRPR 3521
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002602.1 (pep scaffold:Pmarinus_7.0:GL477730:26567:61347:1 gene:ENSPMAG00000002341.1 transcript:ENSPMAT00000002602.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 1.113e-6
Identity = 22/84 (26.19%), Postives = 40/84 (47.62%), Query Frame = 2 
Query: 1208 GEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKH 1459
            G  W H  C  W+    L  + ++  ++ A+  A+   C  C ++GA + C  ++C   +HY CA   G+  +    ++LC  H
Sbjct:  117 GHCWAHHCCAAWSEGVCLSPELELINVDRAVLAAVKQRCQHCRRLGATVKCWVESCSHMYHYPCAAVAGTFQDIRSLALLCPDH 200
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002229.1 (pep scaffold:Pmarinus_7.0:GL477110:4214:18323:-1 gene:ENSPMAG00000002027.1 transcript:ENSPMAT00000002229.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.9062 bits (115), Expect = 2.141e-6
Identity = 23/83 (27.71%), Postives = 39/83 (46.99%), Query Frame = 2 
Query: 1217 WFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKE 1465
            W H  C +W+   +   DG +  +  A+       C  C ++GA + C    C  NFH+ CA +  S + Q+   + C +HK+
Sbjct:  360 WTHSNCAVWSAEVFEDDDGSLKNVHAAVWRGKQLRCEHCGRMGATVGCCLPACQANFHFMCARAR-SCVFQDDKKLYCQRHKD 441
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Match: EDO37587 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFA5])

HSP 1 Score: 53.5286 bits (127), Expect = 6.264e-8
Identity = 26/87 (29.89%), Postives = 39/87 (44.83%), Query Frame = 2 
Query: 1205 DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKE 1465
            DG VW H  C  W+          +  +++A+  A+   C  C + GA + C    C + +HY CA S G+       +MLC  H E
Sbjct:   77 DGSVWAHHCCASWSEGVCQTDSYDLVNVDKAVYQAMTERCAHCSRFGASVVCQVPRCGRTYHYPCAASAGAFQEIHSMTMLCPDHLE 163
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: si:dkey-94l16.4 (transcription factor 20 [Source:NCBI gene;Acc:101162006])

HSP 1 Score: 87.4261 bits (215), Expect = 9.231e-18
Identity = 56/205 (27.32%), Postives = 90/205 (43.90%), Query Frame = 2 
Query:  926 ICAFCGKTSEFLQLGNLYGPYFID--------TENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRIT-------W---------DGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            IC  CG+ +  + LG+L+GPY+ +          + S +       S+++  +       +  +A        L+  ++S + V  +T   +A +   +        W           E W H +C +W+   +L   G++ GLEEA+K A    C  C + GA L C  K C   +HY CA+  G  L +E FSM C KHK K
Sbjct:  644 ICCLCGQPANAMDLGDLHGPYYPEGLRPSTKTAASTSAVKEEEEDFSESDSSSFSRRKSVAPHTAWSVRNQ--LRQNMESRRRVGGATNSPAAKQAILVAGSSESQDWFSPPIVPQEPCEYWLHEDCSVWSAGVFLV-KGRVYGLEEAVKAAHETVCSGCQRSGATLGCVFKGCPNKYHYRCALESGCALIEENFSMKCKKHKNK 845
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: tcf20 (transcription factor 20 [Source:NCBI gene;Acc:101174268])

HSP 1 Score: 77.7962 bits (190), Expect = 1.416e-14
Identity = 35/86 (40.70%), Postives = 49/86 (56.98%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E+W H  CI+W    YL  +G++ GL+EAL  A    C  C  +G+ L C +K C   +HY CA+     LN++ FS+ C KHK K
Sbjct: 2296 ELWVHEGCIVWTSGVYLV-NGRLYGLQEALDGARETSCSYCEMLGSTLGCYSKGCTLRYHYLCAIEADCALNEDNFSLRCPKHKVK 2380
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: tcf20 (transcription factor 20 [Source:NCBI gene;Acc:101174268])

HSP 1 Score: 77.7962 bits (190), Expect = 1.500e-14
Identity = 35/86 (40.70%), Postives = 49/86 (56.98%), Query Frame = 2 
Query: 1211 EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            E+W H  CI+W    YL  +G++ GL+EAL  A    C  C  +G+ L C +K C   +HY CA+     LN++ FS+ C KHK K
Sbjct: 2296 ELWVHEGCIVWTSGVYLV-NGRLYGLQEALDGARETSCSYCEMLGSTLGCYSKGCTLRYHYLCAIEADCALNEDNFSLRCPKHKVK 2380
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: rai1 (retinoic acid induced 1 [Source:NCBI gene;Acc:101163328])

HSP 1 Score: 65.0846 bits (157), Expect = 1.599e-10
Identity = 51/210 (24.29%), Postives = 83/210 (39.52%), Query Frame = 2 
Query:  929 CAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVV------------GASGKSA-IKTDKNGGLKMVIQSSKSVRNSTVKKSASED----------------YRITWDGEV---WFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHK 1462
            C  CGK + +  LG+L GPY+ +      +P   +  +  E   ++S              GAS   A +  DK G  +   Q   S R+   +   +E                  R+  + E    W H  C +W     +   G++ GL+EA   +       C   GA L+C  + C   +HY CA  +G   +++ FS+ C KH+
Sbjct: 1971 CCLCGKPANYKDLGDLCGPYYAE----DSVPRKVLTITHTESFREESNTTCGNDCSTAEKPGASENDAEVNVDKEGNAEASSQEPSSSRHHHWRYRRAERPERSCREGAPRRLTIFQRLRMEAEASEHWAHENCAIWTKGVIMVA-GRLYGLKEAANSS-------CQTEGASLSCCWRGCSHKYHYVCAKEIGCTFHEDDFSIKCPKHE 2168
[Close]
BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Match: rai1 (retinoic acid induced 1 [Source:NCBI gene;Acc:101163328])

HSP 1 Score: 63.929 bits (154), Expect = 3.134e-10
Identity = 56/238 (23.53%), Postives = 87/238 (36.55%), Query Frame = 2 
Query:  929 CAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVV------------GASGKSA-IKTDKNGGLKMVIQSSKSVRN-----------------------------------STVKKSASEDY--------RITWDGEV---WFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKE 1465
            C  CGK + +  LG+L GPY+ +      +P   +  +  E   ++S              GAS   A +  DK G  +   Q   S R+                                     V K AS D         R+  + E    W H  C +W     +   G++ GL+EA   +    C  C   GA L+C  + C   +HY CA  +G   +++ FS+ C KH++
Sbjct: 1971 CCLCGKPANYKDLGDLCGPYYAE----DSVPRKVLTITHTESFREESNTTCGNDCSTAEKPGASENDAEVNVDKEGNAEASSQEPSSSRHHHWRYRRAERPERSCREGAPRRLTLRERFRKMKQLQNVSKGASGDQEGTNSIFQRLRMEAEASEHWAHENCAIWTKGVIMVA-GRLYGLKEAANSSAQTNCYKCQTEGASLSCCWRGCSHKYHYVCAKEIGCTFHEDDFSIKCPKHED 2203
[Close]
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000018860.1 (SMESG000018860.1)

HSP 1 Score: 957.207 bits (2473), Expect = 0.000e+0
Identity = 470/473 (99.37%), Postives = 471/473 (99.58%), Query Frame = 2 
Query:   53 MNQDPPVLQPIDEKEFFNSIENPSLDKTQNSENRFNGYMTNGSGTMSPPMPILYQADREPPNLLNIQDIFSALARDDFDSNNADYSKSTPRKESDSFFEKIYKDYSTTLTNSSNIIDSVKDSTVSPQDTVASELNYSKHDIEIKSELSNNNAEPVHEKTLMKSDSLKSAAKVXXXXXXXXXXPKIISESVTEEVGVKKFGIKSVSAKEKLSGNNKLTPTKTACVNKYLKSPYITLRHGTPKKQCQTVSVISKEYEIINPALRGNGEYQLSSVYRPNLKSVCNNQISNTHPCICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEKW 1471
            MNQDPPVLQPIDEKEFFNSIENPSL+KTQNSENRFNGYMTNGSGTMSPPMPILYQADREPPNLLNIQDIFSALARDDFDSNNADYSKSTPRKESDSFFEKIYKDYSTTLTNSSNIIDSVKDSTVSPQDTVASELNYSKHDIEIKSELSNNNAEPVHEKTLMKSDSLKSAAKVTSTKRSKR RPKIISESVTEEVGVKKFGIKSVSAKEKLSGNNKLTPTKTACVNKYLKSPYITLRHGTPKKQCQTVSVISKEYEIINPALRGNGEYQLSSVYRPNLKSVCNNQISNTHPCICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDN QSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEKW
Sbjct:    1 MNQDPPVLQPIDEKEFFNSIENPSLEKTQNSENRFNGYMTNGSGTMSPPMPILYQADREPPNLLNIQDIFSALARDDFDSNNADYSKSTPRKESDSFFEKIYKDYSTTLTNSSNIIDSVKDSTVSPQDTVASELNYSKHDIEIKSELSNNNAEPVHEKTLMKSDSLKSAAKVTSTKRSKRTRPKIISESVTEEVGVKKFGIKSVSAKEKLSGNNKLTPTKTACVNKYLKSPYITLRHGTPKKQCQTVSVISKEYEIINPALRGNGEYQLSSVYRPNLKSVCNNQISNTHPCICAFCGKTSEFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNHQSVVGASGKSAIKTDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEKW 473
[Close]
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000040592.1 (SMESG000040592.1)

HSP 1 Score: 53.5286 bits (127), Expect = 4.166e-7
Identity = 26/92 (28.26%), Postives = 42/92 (45.65%), Query Frame = 2 
Query: 1205 DGEVWFHRECILWAPCTYL---RGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTK-NCDKNFHYYCAVSLGSKLNQEQFSMLCNKHKEK 1468
            D   + H  C+ W+        + DG    +E  ++  LN  C  C + GA ++C +K NC   FHY CA + G   +   F + C  H ++
Sbjct:  230 DSCFYVHHSCVTWSEGASQFSDQLDGNFDNVESTVRNGLNQMCSFCLRFGATISCRSKTNCKHKFHYPCAAAAGCFQDFVSFQLWCPSHTQE 321
[Close]
BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Match: SMESG000027630.1 (SMESG000027630.1)

HSP 1 Score: 51.9878 bits (123), Expect = 1.093e-6
Identity = 25/82 (30.49%), Postives = 40/82 (48.78%), Query Frame = 2 
Query: 1193 RITWDG-EVWFHRECILWAPCTYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKN--------CDKNFHYYCAVSL 1411
            R+ + G +VW H  C LW+   Y R DG +  ++ A++    A C  C K GA L C+  +        C   +H+ CA ++
Sbjct: 1742 RLIYGGLDVWVHVNCALWSDDVYEREDGALVNVDIAIRKGEKALCAACQKYGATLRCSAPDSLDGCGSSCPNVYHFACAFNM 1823
The following BLAST results are available for this feature:
BLAST of PHD-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TCF204.501e-1544.19transcription factor 20 [Source:HGNC Symbol;Acc:HG... [more]
TCF204.501e-1544.19transcription factor 20 [Source:HGNC Symbol;Acc:HG... [more]
TCF204.501e-1544.19transcription factor 20 [Source:HGNC Symbol;Acc:HG... [more]
TCF204.501e-1544.19transcription factor 20 [Source:HGNC Symbol;Acc:HG... [more]
TCF204.501e-1544.19transcription factor 20 [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
F01D4.55.358e-935.80pep chromosome:WBcel235:IV:10482635:10483594:-1 ge... [more]
F01D4.55.358e-935.80pep chromosome:WBcel235:IV:10482629:10483655:-1 ge... [more]
F01D4.51.607e-635.94pep chromosome:WBcel235:IV:10482686:10483655:-1 ge... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trr2.581e-730.00gene:FBgn0023518 transcript:FBtr0070363[more]
trx2.595e-727.96gene:FBgn0003862 transcript:FBtr0082947[more]
trx2.595e-727.96gene:FBgn0003862 transcript:FBtr0082950[more]
trr2.623e-730.00gene:FBgn0023518 transcript:FBtr0070362[more]
trx2.857e-727.96gene:FBgn0003862 transcript:FBtr0082948[more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-94l16.45.474e-2332.61si:dkey-94l16.4 [Source:ZFIN;Acc:ZDB-GENE-121214-2... [more]
si:ch211-165g14.15.991e-2230.93si:ch211-165g14.1 [Source:ZFIN;Acc:ZDB-GENE-131127... [more]
tcf201.158e-1626.70transcription factor 20 [Source:ZFIN;Acc:ZDB-GENE-... [more]
tcf204.335e-1440.48transcription factor 20 [Source:ZFIN;Acc:ZDB-GENE-... [more]
rai11.731e-1140.00retinoic acid induced 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ltbp34.341e-1426.54latent transforming growth factor beta binding pro... [more]
ltbp34.409e-1426.42latent transforming growth factor beta binding pro... [more]
TCF201.597e-1225.88transcription factor 20 (AR1) [Source:NCBI gene;Ac... [more]
TCF201.970e-1226.32transcription factor 20 (AR1) [Source:NCBI gene;Ac... [more]
TCF203.215e-1226.32transcription factor 20 (AR1) [Source:NCBI gene;Ac... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Zfp9573.633e-1647.62zinc finger protein 957 [Source:MGI Symbol;Acc:MGI... [more]
Zfp9573.633e-1647.62zinc finger protein 957 [Source:MGI Symbol;Acc:MGI... [more]
Rai11.339e-1436.52retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI... [more]
Rai11.339e-1436.52retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI... [more]
Rai11.339e-1436.52retinoic acid induced 1 [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of PHD-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q61818|RAI1_MOUSE9.369e-1436.52Retinoic acid-induced protein 1 OS=Mus musculus OX... [more]
sp|Q9EPQ8|TCF20_MOUSE1.206e-1344.05Transcription factor 20 OS=Mus musculus OX=10090 G... [more]
sp|Q9UGU0|TCF20_HUMAN1.347e-1344.05Transcription factor 20 OS=Homo sapiens OX=9606 GN... [more]
sp|Q7Z5J4|RAI1_HUMAN1.181e-1140.48Retinoic acid-induced protein 1 OS=Homo sapiens OX... [more]
sp|Q8NEZ4|KMT2C_HUMAN1.020e-732.95Histone-lysine N-methyltransferase 2C OS=Homo sapi... [more]
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BLAST of PHD-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5J4NCJ81.171e-4035.34PHD-type domain-containing protein OS=Paragonimus ... [more]
A0A074ZUB23.792e-3838.35PHD-type domain-containing protein OS=Opisthorchis... [more]
A0A4S2M4P11.736e-3738.35PHD-type domain-containing protein OS=Opisthorchis... [more]
A0A504Z1736.584e-3538.24Transcription factor 20 OS=Fasciola gigantica OX=4... [more]
A0A5K3EGI61.166e-3440.11Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000051866.11.291e-1932.42pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000041374.11.983e-1340.96pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000030243.12.221e-1123.83pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
rai12.791e-1125.68retinoic acid induced 1 [Source:ZFIN;Acc:ZDB-GENE-... [more]
kmt2d3.017e-931.82lysine methyltransferase 2D [Source:NCBI gene;Acc:... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000007597.11.821e-1523.24pep scaffold:Pmarinus_7.0:GL478334:30819:39194:1 g... [more]
ENSPMAT00000002322.11.362e-726.14pep scaffold:Pmarinus_7.0:GL477101:2485:64197:1 ge... [more]
ENSPMAT00000002602.11.113e-626.19pep scaffold:Pmarinus_7.0:GL477730:26567:61347:1 g... [more]
ENSPMAT00000002229.12.141e-627.71pep scaffold:Pmarinus_7.0:GL477110:4214:18323:-1 g... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PHD-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO375876.264e-829.89Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PHD-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-94l16.49.231e-1827.32transcription factor 20 [Source:NCBI gene;Acc:1011... [more]
tcf201.416e-1440.70transcription factor 20 [Source:NCBI gene;Acc:1011... [more]
tcf201.500e-1440.70transcription factor 20 [Source:NCBI gene;Acc:1011... [more]
rai11.599e-1024.29retinoic acid induced 1 [Source:NCBI gene;Acc:1011... [more]
rai13.134e-1023.53retinoic acid induced 1 [Source:NCBI gene;Acc:1011... [more]
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BLAST of PHD-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000018860.10.000e+099.37SMESG000018860.1[more]
SMESG000040592.14.166e-728.26SMESG000040592.1[more]
SMESG000027630.11.093e-630.49SMESG000027630.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30002037 ID=SMED30002037|Name=PHD-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1558bp
CTTATTCTGCATATTTTAAATCTTCTTTTATTTATATATTTTGAAATATC
AAATGAATCAGGATCCGCCTGTGCTGCAACCAATAGATGAAAAGGAATTT
TTTAATTCTATTGAAAATCCCTCACTAGACAAAACACAAAATTCAGAGAA
TCGTTTTAATGGTTATATGACAAATGGAAGCGGTACTATGTCTCCCCCAA
TGCCTATATTGTATCAAGCTGACCGAGAACCTCCTAATTTATTAAATATA
CAAGACATATTTTCAGCATTAGCTCGTGATGATTTTGATTCGAATAATGC
AGACTATTCCAAATCTACACCCAGAAAAGAATCTGATTCGTTTTTTGAAA
AAATATATAAAGATTATAGTACTACTCTAACAAATTCGTCGAACATTATA
GATTCTGTTAAAGATTCAACAGTTTCTCCACAAGATACGGTAGCATCAGA
ATTAAATTACTCAAAACATGACATTGAGATCAAATCAGAATTATCTAACA
ATAATGCTGAACCAGTTCATGAAAAAACTTTAATGAAAAGTGATTCGTTA
AAATCCGCAGCTAAAGTTACAAGTACGAAACGATCAAAAAGAAAGAGGCC
TAAAATAATTTCAGAATCTGTTACGGAGGAAGTTGGTGTTAAGAAGTTCG
GTATTAAATCTGTATCCGCTAAAGAAAAATTATCAGGGAATAATAAACTA
ACTCCTACTAAGACTGCATGTGTTAATAAATATCTGAAATCTCCTTATAT
TACTCTAAGACACGGTACTCCAAAGAAGCAATGCCAAACCGTTAGTGTTA
TCAGCAAAGAATATGAAATAATTAACCCTGCATTACGGGGAAATGGGGAA
TATCAGTTATCGTCAGTCTATCGTCCAAATCTGAAAAGTGTATGTAACAA
TCAAATTTCTAATACCCATCCATGTATTTGTGCTTTTTGTGGTAAAACCT
CAGAGTTTCTCCAGTTAGGAAATTTATACGGACCTTATTTCATCGATACA
GAAAATATATCCGGTCTCCCTTTAACTTGTATGTTCCCTTCAGATAATGA
ACAAGATAACCAGCAATCAGTCGTTGGTGCATCCGGTAAATCGGCCATTA
AAACTGATAAAAATGGTGGTCTTAAAATGGTTATTCAATCATCAAAAAGT
GTTAGAAATAGTACTGTTAAAAAATCCGCTTCAGAAGATTACAGAATCAC
TTGGGATGGTGAAGTGTGGTTTCATAGAGAGTGCATTTTATGGGCTCCCT
GTACGTATTTGAGAGGAGATGGGAAAATCGGTGGCTTAGAAGAAGCCTTG
AAAATGGCTTTAAATGCGGAATGCTGTGTGTGTCACAAAATCGGTGCTAT
TCTCAATTGTACTACCAAAAACTGTGACAAGAATTTCCATTATTATTGTG
CGGTATCCCTCGGTTCCAAATTGAATCAGGAACAGTTTTCAATGCTGTGT
AATAAACATAAGGAAAAATGGTAACAGATATCAAATATCAGGGCTTTCTT
TGTAAATACATATATATTTTGTTGGTTTTTATGTACTTATATAGAAAACT
CGTGGATG
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protein sequence of SMED30002037-orf-1

>SMED30002037-orf-1 ID=SMED30002037-orf-1|Name=SMED30002037-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=474bp
MNQDPPVLQPIDEKEFFNSIENPSLDKTQNSENRFNGYMTNGSGTMSPPM
PILYQADREPPNLLNIQDIFSALARDDFDSNNADYSKSTPRKESDSFFEK
IYKDYSTTLTNSSNIIDSVKDSTVSPQDTVASELNYSKHDIEIKSELSNN
NAEPVHEKTLMKSDSLKSAAKVTSTKRSKRKRPKIISESVTEEVGVKKFG
IKSVSAKEKLSGNNKLTPTKTACVNKYLKSPYITLRHGTPKKQCQTVSVI
SKEYEIINPALRGNGEYQLSSVYRPNLKSVCNNQISNTHPCICAFCGKTS
EFLQLGNLYGPYFIDTENISGLPLTCMFPSDNEQDNQQSVVGASGKSAIK
TDKNGGLKMVIQSSKSVRNSTVKKSASEDYRITWDGEVWFHRECILWAPC
TYLRGDGKIGGLEEALKMALNAECCVCHKIGAILNCTTKNCDKNFHYYCA
VSLGSKLNQEQFSMLCNKHKEKW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0008270zinc ion binding
GO:0005515protein binding
GO:0016491oxidoreductase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR034732EPHD
IPR001965Znf_PHD
IPR013083Znf_RING/FYVE/PHD
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001965Zinc finger, PHD-typeSMARTSM00249PHD_3coord: 423..470
e-value: 0.0033
score: 26.7
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3DG3DSA:3.30.40.10coord: 366..472
e-value: 2.8E-18
score: 68.2
NoneNo IPR availablePFAMPF13771zf-HC5HC2Hcoord: 391..470
e-value: 1.4E-11
score: 44.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..32
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 161..183
NoneNo IPR availablePANTHERPTHR14955RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20coord: 282..472
IPR034732Extended PHD (ePHD) domainPROSITEPS51805EPHDcoord: 363..470
score: 12.871