vasohibin-2

Overview
Namevasohibin-2
Smed IDSMED30001975
Length (bp)1106
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of vasohibin-2 (SMED30001975) t-SNE clustered cells

Violin plots show distribution of expression levels for vasohibin-2 (SMED30001975) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of vasohibin-2 (SMED30001975) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for vasohibin-2 (SMED30001975) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001975

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30001975SMESG000072424.1 dd_Smed_v4_12833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30001975SMESG000072424.1 dd_Smed_v4_12833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30001975SMESG000072424.1 dd_Smed_v6_12833_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30001975SMESG000072424.1 dd_Smed_v4_12833_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 220.705 bits (561), Expect = 1.569e-68
Identity = 110/248 (44.35%), Postives = 163/248 (65.73%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N  GFP++  ++ RM      ++ +  E + +I       K  P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDLI  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   46 GVLFHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAK--PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 291
[Close]
BLAST of vasohibin-2 vs. Ensembl Human
Match: VASH1 (vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964])

HSP 1 Score: 219.55 bits (558), Expect = 7.460e-68
Identity = 106/248 (42.74%), Postives = 163/248 (65.73%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYP--EVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N GG P++E ++ RM +    ++  D E +   ++   +  K P   VP     +  +  ++EA+Q Y+++L+YN TGTQFF IK +R L GLM+ AKE+   +LPIKCLEAVILGIYLTN +  LERF I F++ F G  F+H+VLG+   G YGA+GMSRRE+LM+KP  F +LS+L++ +  AY +  H L +V +G+++SHD  S+E I WK  V+ +  L  + F++E+E+++R +R
Sbjct:   57 GVPFFVNRGGLPVDEATWERMWKHVAKIHP-DGEKVAQRIRGATDLPKIPIPSVP-TFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMR 302
[Close]
BLAST of vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 210.69 bits (535), Expect = 2.066e-65
Identity = 100/199 (50.25%), Postives = 142/199 (71.36%), Query Frame = 2 
Query:  215 PEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDLI  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   28 PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 226
[Close]
BLAST of vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 210.69 bits (535), Expect = 2.066e-65
Identity = 100/199 (50.25%), Postives = 142/199 (71.36%), Query Frame = 2 
Query:  215 PEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDLI  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   28 PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 226
[Close]
BLAST of vasohibin-2 vs. Ensembl Human
Match: VASH2 (vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723])

HSP 1 Score: 205.682 bits (522), Expect = 4.955e-64
Identity = 97/181 (53.59%), Postives = 132/181 (72.93%), Query Frame = 2 
Query:  263 IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDLI  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:    7 LQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 187
[Close]
BLAST of vasohibin-2 vs. Ensembl Zebrafish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:100001748])

HSP 1 Score: 219.935 bits (559), Expect = 3.787e-68
Identity = 104/250 (41.60%), Postives = 166/250 (66.40%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVP----RMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + FIIN GG P+NE ++ +M      ++ +     E + ++    +  P++P         +I ++ ++EAIQ Y++ L+YN TGTQFF IK +R L  LM+ AKE+   SLPIKCLEAVILGIYLTN +  +ERF + F++ F G  F+H+VLG++S G +GA+G+SRR++LM+K L + +LSDL++ + +AY+   H+L RV IG  +SHD  S+E I WK  V+ ++ L+  + ++E+E+++R +R
Sbjct:   63 GVPFIINRGGLPVNEETWEQMWRHVARIHPDG----EQLARRIRGTRDLPKIPVPSVPTFQPSISIAHRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPLSFKTQFSGSHFRHIVLGVHSGGRFGALGISRRQDLMYKSLQYKTLSDLLLDFQEAYRGHWHTLCRVRIGHYVSHDPHSVEQIEWKHSVLDVDKLTREELRKELERHTRDMR 308
[Close]
BLAST of vasohibin-2 vs. Ensembl Zebrafish
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 211.075 bits (536), Expect = 5.928e-65
Identity = 111/283 (39.22%), Postives = 167/283 (59.01%), Query Frame = 2 
Query:   56 EAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKP 898
            E    + F +N  GFP+  +++ RM      ++ +  E ++ I    +  K    VP + N    +SV   + A+Q+YM+ L+YN TGTQFF IK  R L+GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ +ERF I F++ F G  F HVVLG+Y NG YG +GMSRR +LM + L F +LS+L+  +  +Y++  H++ ++ IG  + H+    +PI W  +VI  +       ++E+EK+ R +R +     S Q    P   R    S +  R+P
Sbjct:   55 EKDGGVPFFVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNATLLPKH--SVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKHGRDMRMKILKSSSAQS---PIKERTRGKSLSPRRRP 332
[Close]
BLAST of vasohibin-2 vs. Ensembl Zebrafish
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 211.075 bits (536), Expect = 5.928e-65
Identity = 111/283 (39.22%), Postives = 167/283 (59.01%), Query Frame = 2 
Query:   56 EAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKP 898
            E    + F +N  GFP+  +++ RM      ++ +  E ++ I    +  K    VP + N    +SV   + A+Q+YM+ L+YN TGTQFF IK  R L+GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ +ERF I F++ F G  F HVVLG+Y NG YG +GMSRR +LM + L F +LS+L+  +  +Y++  H++ ++ IG  + H+    +PI W  +VI  +       ++E+EK+ R +R +     S Q    P   R    S +  R+P
Sbjct:   55 EKDGGVPFFVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNATLLPKH--SVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKHGRDMRMKILKSSSAQS---PIKERTRGKSLSPRRRP 332
[Close]
BLAST of vasohibin-2 vs. Ensembl Zebrafish
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 206.838 bits (525), Expect = 1.520e-64
Identity = 103/247 (41.70%), Postives = 156/247 (63.16%), Query Frame = 2 
Query:   71 IQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            + F +N  GFP+  +++ RM      ++ +  E ++ I    +  K    VP + N    +SV   + A+Q+YM+ L+YN TGTQFF IK  R L+GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ +ERF I F++ F G  F HVVLG+Y NG YG +GMSRR +LM + L F +LS+L+  +  +Y++  H++ ++ IG  + H+    +PI W  +VI  +       ++E+EK+ R +R
Sbjct:    2 VPFFVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNATLLPKH--SVPSVPNFKPSMSVPDWLHAVQNYMRNLQYNHTGTQFFEIKKTRPLSGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSVERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDRSLSFRTLSELVFDFEDSYRRYQHTMKKIKIGLYVPHNPHVFQPIEWNYLVINASKQGREDMRKELEKHGRDMR 246
[Close]
BLAST of vasohibin-2 vs. Ensembl Xenopus
Match: serinc5 (serine incorporator 5 [Source:Xenbase;Acc:XB-GENE-1008360])

HSP 1 Score: 217.238 bits (552), Expect = 3.044e-67
Identity = 108/252 (42.86%), Postives = 159/252 (63.10%), Query Frame = 2 
Query:   53 NEAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILK-QHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            +E      F +N GG P++E ++ RM +F    + +    +  I + Q + +   P VP   +    +  +IEAIQ Y+++L+YN TGTQFF IK  R L GLM+ AKE+   +LPIKCLEAVIL IYLTN I+ LERF I F++ F G  F+H+VLGL+    +GA+G+SRR++LM+KPL   +LSDL+  +  AY +  H+L +V IG  +SHD  S+E I WK  V+ +  L     + E+E++SR++R
Sbjct:   37 DEEDGGAPFYVNRGGLPIDEPTWERMWQFVGKTHPDGEALVRRIREAQDLPRVPAPSVP-SFHVGATVPERIEAIQRYIRELQYNHTGTQFFEIKKTRPLTGLMDLAKEMTKEALPIKCLEAVILAIYLTNSIAGLERFPISFKTQFSGGCFRHIVLGLHWGNHFGALGISRRDDLMYKPLKHRTLSDLLADFQDAYSKCWHTLRKVKIGRYVSHDPHSVEQIDWKHSVLDVQELGTEGLRRELERHSREMR 287
[Close]
BLAST of vasohibin-2 vs. Ensembl Xenopus
Match: mios (missing oocyte, meiosis regulator, homolog [Source:Xenbase;Acc:XB-GENE-5959761])

HSP 1 Score: 213.772 bits (543), Expect = 7.617e-66
Identity = 106/246 (43.09%), Postives = 156/246 (63.41%), Query Frame = 2 
Query:   74 QFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             F +N  GFP++  ++ RM      ++ E  + ++ I    +  K  P +P +      +S+   ++A+Q YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG++ NG YG +GMSRR +LM KPL F +LS+LI  + ++Y+   H++ +V IG  + HD  + +PI WK +VI +  +     K+ +EK++R +R
Sbjct:   71 HFYVNKSGFPIDSQTWERMWGHVAKIHPEGKDMVDKIRNATLLAK--PSIPAVPTYKASMSIPEWLQAVQRYMKLLQYNHTGTQFFEIRKTRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSVERFPISFKTQFSGSFFHHVVLGIHCNGHYGTLGMSRRSDLMDKPLTFRTLSELIFDFEESYKNYLHTVKKVKIGLYVPHDPHTFQPIEWKHLVINMGKMMKADIKKVLEKHARDMR 314
[Close]
BLAST of vasohibin-2 vs. Ensembl Xenopus
Match: mios (missing oocyte, meiosis regulator, homolog [Source:Xenbase;Acc:XB-GENE-5959761])

HSP 1 Score: 127.102 bits (318), Expect = 2.747e-33
Identity = 74/246 (30.08%), Postives = 120/246 (48.78%), Query Frame = 2 
Query:   74 QFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             F +N  GFP++  ++ RM      ++ E  + ++ I    +  K  P +P +      +S+   ++A+Q YMK L+Y                                            LTNG   +ERF I F++ F G  F HVVLG++ NG YG +GMSRR +LM KPL F +LS+LI  + ++Y+   H++ +V IG  + HD  + +PI WK +VI +  +     K+ +EK++R +R
Sbjct:   71 HFYVNKSGFPIDSQTWERMWGHVAKIHPEGKDMVDKIRNATLLAK--PSIPAVPTYKASMSIPEWLQAVQRYMKLLQY--------------------------------------------LTNGQPSVERFPISFKTQFSGSFFHHVVLGIHCNGHYGTLGMSRRSDLMDKPLTFRTLSELIFDFEESYKNYLHTVKKVKIGLYVPHDPHTFQPIEWKHLVINMGKMMKADIKKVLEKHARDMR 270
[Close]
BLAST of vasohibin-2 vs. Ensembl Mouse
Match: Vash2 (vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826])

HSP 1 Score: 219.935 bits (559), Expect = 2.411e-68
Identity = 109/248 (43.95%), Postives = 162/248 (65.32%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N  GFP++  ++ RM      ++    E + +I       K  P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDL+  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   46 GVLFHVNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAK--PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 291
[Close]
BLAST of vasohibin-2 vs. Ensembl Mouse
Match: Vash2 (vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826])

HSP 1 Score: 219.935 bits (559), Expect = 2.411e-68
Identity = 109/248 (43.95%), Postives = 162/248 (65.32%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N  GFP++  ++ RM      ++    E + +I       K  P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDL+  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   46 GVLFHVNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAK--PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 291
[Close]
BLAST of vasohibin-2 vs. Ensembl Mouse
Match: Vash1 (vasohibin 1 [Source:MGI Symbol;Acc:MGI:2442543])

HSP 1 Score: 219.164 bits (557), Expect = 8.557e-68
Identity = 108/248 (43.55%), Postives = 160/248 (64.52%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYP--EVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F IN GG P++E ++ RM +    ++  D E +   ++   +  K P   VP        +  ++EA+Q Y+++L+YN TGTQFF IK +R L GLM+ AKE+   +LPIKCLEAVILGIYLTN +  LERF I F++ F G  F+H+VLG+   G YGA+GMSRRE+LM+KP  F +LS+L++ Y  AY +  H L +V +G+ +SHD  S+E I WK  V+ +  L    F++E+E+++R +R
Sbjct:   67 GVPFFINRGGLPVDEATWERMWKHVAKIHP-DGEKVALRIRGATDLPKIPIPSVP-TFQPTTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFGGRYGALGMSRREDLMYKPPAFRTLSELVLDYEAAYGRCWHVLKKVKLGQCVSHDPHSVEQIEWKHSVLDVERLGREDFRKELERHARDMR 312
[Close]
BLAST of vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q86V25|VASH2_HUMAN (Tubulinyl-Tyr carboxypeptidase 2 OS=Homo sapiens OX=9606 GN=VASH2 PE=1 SV=2)

HSP 1 Score: 220.705 bits (561), Expect = 7.537e-68
Identity = 110/248 (44.35%), Postives = 163/248 (65.73%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N  GFP++  ++ RM      ++ +  E + +I       K  P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDLI  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   46 GVLFHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAK--PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 291
[Close]
BLAST of vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q8C5G2|VASH2_MOUSE (Tubulinyl-Tyr carboxypeptidase 2 OS=Mus musculus OX=10090 GN=Vash2 PE=1 SV=2)

HSP 1 Score: 219.935 bits (559), Expect = 1.687e-67
Identity = 109/248 (43.95%), Postives = 162/248 (65.32%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVK--IEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N  GFP++  ++ RM      ++    E + +I       K  P +P++ N  + +++   ++AIQ+YMK L+YN TGTQFF I+  R L+GLME+AKE+   SLPIKCLEAVILGIYLTNG   +ERF I F++ F G  F HVVLG+Y NG YG++GMSRR ELM KPL F +LSDL+  +  +Y++  H++ +V IG  + H+  S +PI WK +V+ ++ +     ++E+EKY+R +R
Sbjct:   46 GVLFHVNKSGFPIDSHTWERMWLHVAKVHPRGGEMVGAIRNAAFLAK--PSIPQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGYYGSLGMSRRAELMDKPLTFRTLSDLVFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMR 291
[Close]
BLAST of vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q7L8A9|VASH1_HUMAN (Tubulinyl-Tyr carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=VASH1 PE=1 SV=1)

HSP 1 Score: 219.55 bits (558), Expect = 3.583e-67
Identity = 106/248 (42.74%), Postives = 163/248 (65.73%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYP--EVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N GG P++E ++ RM +    ++  D E +   ++   +  K P   VP     +  +  ++EA+Q Y+++L+YN TGTQFF IK +R L GLM+ AKE+   +LPIKCLEAVILGIYLTN +  LERF I F++ F G  F+H+VLG+   G YGA+GMSRRE+LM+KP  F +LS+L++ +  AY +  H L +V +G+++SHD  S+E I WK  V+ +  L  + F++E+E+++R +R
Sbjct:   57 GVPFFVNRGGLPVDEATWERMWKHVAKIHP-DGEKVAQRIRGATDLPKIPIPSVP-TFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMR 302
[Close]
BLAST of vasohibin-2 vs. UniProt/SwissProt
Match: sp|Q8C1W1|VASH1_MOUSE (Tubulinyl-Tyr carboxypeptidase 1 OS=Mus musculus OX=10090 GN=Vash1 PE=1 SV=4)

HSP 1 Score: 219.164 bits (557), Expect = 5.986e-67
Identity = 108/248 (43.55%), Postives = 160/248 (64.52%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYP--EVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F IN GG P++E ++ RM +    ++  D E +   ++   +  K P   VP        +  ++EA+Q Y+++L+YN TGTQFF IK +R L GLM+ AKE+   +LPIKCLEAVILGIYLTN +  LERF I F++ F G  F+H+VLG+   G YGA+GMSRRE+LM+KP  F +LS+L++ Y  AY +  H L +V +G+ +SHD  S+E I WK  V+ +  L    F++E+E+++R +R
Sbjct:   67 GVPFFINRGGLPVDEATWERMWKHVAKIHP-DGEKVALRIRGATDLPKIPIPSVP-TFQPTTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFGGRYGALGMSRREDLMYKPPAFRTLSELVLDYEAAYGRCWHVLKKVKLGQCVSHDPHSVEQIEWKHSVLDVERLGREDFRKELERHARDMR 312
[Close]
BLAST of vasohibin-2 vs. TrEMBL
Match: A0A267DDW9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028228g4 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 9.280e-70
Identity = 126/287 (43.90%), Postives = 175/287 (60.98%), Query Frame = 2 
Query:   77 FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVN---QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLP---FLPRCNLDSTAALRKPQALKDST 919
            F+ N  GFP+++ ++  M +F++Y   +  E I SI     N   + K P  P         S KI A+Q Y  +L+YN TGTQFF IK  R+  GLME AK++I  SLPIKCLEAV+LGIYLTN I  L RF IGF+S+F G V +HVVLGLYS G++GA+G+SRR++LM+KPL F +L++LI+ Y  AYQ+  H L +V IG  I  +  S EP+ WKG+ +  +     + + E+EK+S+ +R  A+   S QQ        LPR    S  AL +P + + S 
Sbjct:   11 FLTNKNGFPIDDGTWSNMWKFAEYQQPKAKEKIRSIRATSANDLAEPKIPVPPLTFPIGSTTSSKILAVQKYFAELQYNHTGTQFFEIKKYRSFTGLMEDAKQMIKESLPIKCLEAVVLGIYLTNKIEDLTRFAIGFKSVFNGHVHRHVVLGLYSKGMFGALGISRRDDLMYKPLTFKTLTELIMEYKAAYQRHWHKLKQVKIGMAIGKNPHSFEPLPWKGLTVFPSSQPFEEMRSELEKFSKLVRHGASF--SHQQQAAARRERLPRSA--SLPALSQPASPQRSA 293
[Close]
BLAST of vasohibin-2 vs. TrEMBL
Match: A0A267DDU8 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028228g3 PE=4 SV=1)

HSP 1 Score: 231.876 bits (590), Expect = 1.028e-69
Identity = 128/299 (42.81%), Postives = 180/299 (60.20%), Query Frame = 2 
Query:   44 ENINEAFKNIQ-FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVN---QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLP---FLPRCNLDSTAALRKPQALKDST 919
            +++N  F     F+ N  GFP+++ ++  M +F++Y   +  E I SI     N   + K P  P         S KI A+Q Y  +L+YN TGTQFF IK  R+  GLME AK++I  SLPIKCLEAV+LGIYLTN I  L RF IGF+S+F G V +HVVLGLYS G++GA+G+SRR++LM+KPL F +L++LI+ Y  AYQ+  H L +V IG  I  +  S EP+ WKG+ +  +     + + E+EK+S+ +R  A+   S QQ        LPR    S  AL +P + + S 
Sbjct:   23 DDMNADFDETTLFLTNKNGFPIDDGTWSNMWKFAEYQQPKAKEKIRSIRATSANDLAEPKIPVPPLTFPIGSTTSSKILAVQKYFAELQYNHTGTQFFEIKKYRSFTGLMEDAKQMIKESLPIKCLEAVVLGIYLTNKIEDLTRFAIGFKSVFNGHVHRHVVLGLYSKGMFGALGISRRDDLMYKPLTFKTLTELIMEYKAAYQRHWHKLKQVKIGMAIGKNPHSFEPLPWKGLTVFPSSQPFEEMRSELEKFSKLVRHGASF--SHQQQAAARRERLPRSA--SLPALSQPASPQRSA 317
[Close]
BLAST of vasohibin-2 vs. TrEMBL
Match: A0A267H6J2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028228g1 PE=4 SV=1)

HSP 1 Score: 229.95 bits (585), Expect = 3.275e-69
Identity = 126/287 (43.90%), Postives = 174/287 (60.63%), Query Frame = 2 
Query:   77 FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVN---QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLP---FLPRCNLDSTAALRKPQALKDST 919
            F+ N  GFP+++ ++  M +F++Y   +  E I SI     N   + K P  P         S KI A+Q Y  +L+YN TGTQFF IK  R+  GLME AK++I  SLPIKCLEAV+LGIYLTN I  L RF IGF+S F G V +HVVLGLYS G++GA+G+SRR++LM+KPL F +L++LI+ Y  AYQ+  H L +V IG  I  +  S EP+ WKG+ +  +     + + E+EK+S+ +R  A+   S QQ        LPR    S  AL +P + + S 
Sbjct:   11 FLTNKNGFPIDDGTWSNMWKFAEYQQPKAKEKIRSIRATPANDLAEPKIPVPPLTFPIGSTTSSKILAVQKYFAELQYNHTGTQFFEIKKYRSFTGLMEDAKQMIKESLPIKCLEAVVLGIYLTNKIEDLTRFAIGFKSAFNGHVHRHVVLGLYSKGMFGALGISRRDDLMYKPLTFKTLTELIMEYKAAYQRHWHKLKQVKIGMAIGKNPHSFEPLPWKGLTVFPSSQPFEEMRSELEKFSKLVRHGASF--SHQQQAAARRERLPRSA--SLPALSQPASPQRSA 293
[Close]
BLAST of vasohibin-2 vs. TrEMBL
Match: A0A267DS33 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028228g2 PE=4 SV=1)

HSP 1 Score: 229.565 bits (584), Expect = 4.477e-69
Identity = 126/287 (43.90%), Postives = 174/287 (60.63%), Query Frame = 2 
Query:   77 FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVN---QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLP---FLPRCNLDSTAALRKPQALKDST 919
            F+ N  GFP+++ ++  M +F++Y   +  E I SI     N   + K P  P         S KI A+Q Y  +L+YN TGTQFF IK  R+  GLME AK++I  SLPIKCLEAV+LGIYLTN I  L RF IGF+S F G V +HVVLGLYS G++GA+G+SRR++LM+KPL F +L++LI+ Y  AYQ+  H L +V IG  I  +  S EP+ WKG+ +  +     + + E+EK+S+ +R  A+   S QQ        LPR    S  AL +P + + S 
Sbjct:   11 FLTNKNGFPIHDGTWSNMWKFAEYQQPKAKEKIRSIRATPANDLAEPKIPVPPLTFPIGSTTSSKILAVQKYFAELQYNHTGTQFFEIKKYRSFTGLMEDAKQMIKESLPIKCLEAVVLGIYLTNKIEDLTRFAIGFKSAFNGHVHRHVVLGLYSKGMFGALGISRRDDLMYKPLTFKTLTELIMEYKAAYQRHWHKLKQVKIGMAIGKNPHSFEPLPWKGLTVFPSSQPFEEMRSELEKFSKLVRHGASF--SHQQQAAARRERLPRSA--SLPALSQPASPQRSA 293
[Close]
BLAST of vasohibin-2 vs. TrEMBL
Match: A0A3B3H867 (Vasohibin 2 OS=Oryzias latipes OX=8090 GN=vash2 PE=4 SV=1)

HSP 1 Score: 229.18 bits (583), Expect = 2.260e-68
Identity = 118/271 (43.54%), Postives = 169/271 (62.36%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESIL-KQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSR--KLRKQAAIRGSIQQHYLPFLPRCNL 871
             +QF +N  GFP++  ++ RM      L+ E  E +  I    ++ +   P VP    +++ +S  +  +Q YMK L+YN TGTQFF IK +R L GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG++GMSRR++LM KPL   +L DL+  +  +YQ+  H+L +V IG  + HD    +PI WK +V+  + L     K+E+EK+ R  K++  +    S  QH   +LP  +L
Sbjct:   62 GVQFYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVP-TFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMKMKVLSGEETSRAQHPQRWLPDPHL 331
[Close]
BLAST of vasohibin-2 vs. Ensembl Cavefish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:103022300])

HSP 1 Score: 222.631 bits (566), Expect = 3.386e-69
Identity = 112/248 (45.16%), Postives = 165/248 (66.53%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSV--KIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             I FIIN GG P+NE ++ +M      ++  D E +   ++   +  K P +P +       S+  ++EAIQ Y++ L+YN TGTQFF IK +R L  LM+ AKE+   SLPIKCLEAVILGIYLTN +  +ERF I F++ F G  F+H+VLG++S G +GA+G+SRRE+LM+KPL F +L+DL+  Y  AYQ   H+L +V IG+ +SHD  S+E I WK  V+ ++ LS  + ++E+E+++R +R
Sbjct:   67 GIPFIINRGGLPVNEETWEQMWRHVARIHP-DGEVVGKRIRGVTDLPKIP-IPTVPTYQPTTSIPQRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMYKPLEFRTLADLLQEYQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHTRDMR 312
[Close]
BLAST of vasohibin-2 vs. Ensembl Cavefish
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:103022300])

HSP 1 Score: 214.157 bits (544), Expect = 1.058e-65
Identity = 112/269 (41.64%), Postives = 163/269 (60.59%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKK-----------------------YPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             I FIIN GG P+NE ++ +M      ++  D E +   ++   +  K                        P VP        +  ++EAIQ Y++ L+YN TGTQFF IK +R L  LM+ AKE+   SLPIKCLEAVILGIYLTN +  +ERF I F++ F G  F+H+VLG++S G +GA+G+SRRE+LM+KPL F +L+DL+  Y  AYQ   H+L +V IG+ +SHD  S+E I WK  V+ ++ LS  + ++E+E+++R +R
Sbjct:   67 GIPFIINRGGLPVNEETWEQMWRHVARIHP-DGEVVGKRIRGVTDLPKEMRTFCLADFALWLFFDTSCWIPIPTVP-TYQPTTSIPQRLEAIQKYIRDLQYNHTGTQFFEIKKSRPLTALMDIAKEMTRESLPIKCLEAVILGIYLTNSMPSVERFPISFKTQFSGSHFRHIVLGIHSGGRFGALGISRREDLMYKPLEFRTLADLLQEYQTAYQGYWHTLRKVKIGQYVSHDPHSVEQIEWKHSVLDVDKLSKEELRKELERHTRDMR 333
[Close]
BLAST of vasohibin-2 vs. Ensembl Cavefish
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:103025056])

HSP 1 Score: 212.231 bits (539), Expect = 2.935e-65
Identity = 108/255 (42.35%), Postives = 157/255 (61.57%), Query Frame = 2 
Query:   53 NEAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVKI----EAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            +E    + F +N  GFP+  +++ RM      ++ +  E ++ I     N    P+ P  L  N K S+ +     A+Q+YMK L+YN TGTQFF I+  R L GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG +GMSRR +LM K L F +LS+L+  +  +Y++  H++ +V IG  + H+    +PI WK +V+          ++E+EK+ R +R
Sbjct:   58 DEKDGGVPFYVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIR----NAAHLPKQPVPLVPNFKPSMSVPDWLHAVQNYMKNLQYNHTGTQFFEIRKTRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGLTSLERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDKSLSFRTLSELVFEFEDSYRRYQHTIKKVKIGLYVPHNPHVFQPIEWKYLVLNPCRQGREDMRKELEKHGRDMR 308
[Close]
BLAST of vasohibin-2 vs. Ensembl Cavefish
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:103025056])

HSP 1 Score: 177.563 bits (449), Expect = 6.405e-52
Identity = 97/258 (37.60%), Postives = 149/258 (57.75%), Query Frame = 2 
Query:   53 NEAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLN-------GLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            +E    + F +N  GFP+  +++ RM      ++ +  E ++ I       K  P VP     ++ +   + A+Q+YMK L+Y    TQ      N++ +        LME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG +GMSRR +LM K L F +LS+L+  +  +Y++  H++ +V IG  + H+    +PI WK +V+          ++E+EK+ R +R
Sbjct:   58 DEKDGGVPFYVNRTGFPIESVTWERMWSHVAKVHPDGQEMVDRIRNAAHLPKPVPLVPN-FKPSMSVPDWLHAVQNYMKNLQYPSHETQ------NKDKSFLLTIGEVLMETAREMIRESLPIKCLEAVILGIYLTNGLTSLERFPISFKTQFSGHHFHHVVLGVYCNGRYGTLGMSRRTDLMDKSLSFRTLSELVFEFEDSYRRYQHTIKKVKIGLYVPHNPHVFQPIEWKYLVLNPCRQGREDMRKELEKHGRDMR 308
[Close]
BLAST of vasohibin-2 vs. Ensembl Sea Lamprey
Match: vash2 (vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355])

HSP 1 Score: 177.948 bits (450), Expect = 4.800e-54
Identity = 88/201 (43.78%), Postives = 130/201 (64.68%), Query Frame = 2 
Query:  203 QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            Q  +P VP     ++ +  ++ A+Q YM++L+YN TGTQFF I+ +R L GLM++A+E++  SLPIKCLEAVILGI+LTNGI  +ERF + F+S F G  F+HVVL        G++GMSRR +LM K L F SL DLI  + +AY+   H++ R+ +G ++ HDS S E I W  + +        + +  +E++SR +R
Sbjct:    1 QPPFPAVP-TFRPSMPIPERLLAVQIYMRELQYNHTGTQFFEIRKSRPLVGLMDAAREMVQESLPIKCLEAVILGIHLTNGIPGVERFPLSFKSQFCGRTFRHVVL--------GSLGMSRRPDLMHKQLTFRSLYDLIADFQEAYRGYLHTVTRIKVGLSVPHDSQSFETIAWGHLTLDTLRTGAAETRSRLERHSRDIR 192
[Close]
BLAST of vasohibin-2 vs. Ensembl Sea Lamprey
Match: VASH1 (vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964])

HSP 1 Score: 162.925 bits (411), Expect = 3.158e-48
Identity = 76/208 (36.54%), Postives = 127/208 (61.06%), Query Frame = 2 
Query:  203 QKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRG 826
            Q   P +P +L +   L  +++AIQ YM  L+YN TGTQFF I+ NR + GLM+ A++++  +L      +  L  YLTNG+  +ERF + FR+ F G  F+HVVLG+   G YGA+G+SRR ELMFK      L+ L+  + +AY    H++ R+ +G  + HD  S + + W+ +V+ ++ LS  + + +++K++R ++    ++G
Sbjct:    1 QVPVPSLPTLLPAVAMLD-RLKAIQKYMMDLQYNHTGTQFFEIRKNRPIAGLMDLARDMVREALACNLCASNTLNCYLTNGLPGVERFPLSFRTRFGGSAFRHVVLGVCVGGRYGALGLSRRPELMFKAATHAGLAPLVADFRQAYSSYRHAVTRLKVGLYVPHDPRSFQQVEWRHLVVDVSRLSGEELRRDLDKHARDMKAVQVLKG 207
[Close]
BLAST of vasohibin-2 vs. Ensembl Nematostella
Match: EDO40230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7P4])

HSP 1 Score: 190.66 bits (483), Expect = 4.603e-59
Identity = 92/193 (47.67%), Postives = 136/193 (70.47%), Query Frame = 2 
Query:  245 IKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIR 823
            + ++ K+  IQ Y+++L+YN TGTQ F IK  R   GLM++A+EII  SLPIKCLEAVI+ +YLT+ +S+L+RFTIGF++ F   +++HVVLG+++NG YGA+G+SRR++LM+KPL F SL DL+  +V++Y    HS+ ++ +   I HD  S E I WK + +    LS +  K+ +EKYSR+LR     R
Sbjct:   42 LTVTEKLVLIQKYLQQLQYNHTGTQLFEIKKYRPYTGLMDTAREIIKESLPIKCLEAVIVSLYLTSSMSELQRFTIGFKTQFGSSIYRHVVLGVHANGKYGALGLSRRDDLMYKPLTFKSLCDLLNDFVESYGNYLHSVKKIKLSLPIVHDLHSCEKIHWKYLALSPAKLSASDMKKILEKYSRELRTTVRDR 234
[Close]
BLAST of vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 229.18 bits (583), Expect = 8.508e-72
Identity = 118/271 (43.54%), Postives = 169/271 (62.36%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESIL-KQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSR--KLRKQAAIRGSIQQHYLPFLPRCNL 871
             +QF +N  GFP++  ++ RM      L+ E  E +  I    ++ +   P VP    +++ +S  +  +Q YMK L+YN TGTQFF IK +R L GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG++GMSRR++LM KPL   +L DL+  +  +YQ+  H+L +V IG  + HD    +PI WK +V+  + L     K+E+EK+ R  K++  +    S  QH   +LP  +L
Sbjct:   62 GVQFYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVP-TFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMKMKVLSGEETSRAQHPQRWLPDPHL 331
[Close]
BLAST of vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 227.639 bits (579), Expect = 3.003e-71
Identity = 111/247 (44.94%), Postives = 159/247 (64.37%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESIL-KQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             +QF +N  GFP++  ++ RM      L+ E  E +  I    ++ +   P VP    +++ +S  +  +Q YMK L+YN TGTQFF IK +R L GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG++GMSRR++LM KPL   +L DL+  +  +YQ+  H+L +V IG  + HD    +PI WK +V+  + L     K+E+EK+ R ++
Sbjct:   62 GVQFYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVP-TFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMK 307
[Close]
BLAST of vasohibin-2 vs. Ensembl Medaka
Match: VASH1 (vasohibin 1 [Source:NCBI gene;Acc:101166671])

HSP 1 Score: 214.927 bits (546), Expect = 9.798e-67
Identity = 104/248 (41.94%), Postives = 166/248 (66.94%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSV--KIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             + F +N GG P++E ++ RM      ++  + E +   ++   +  K P +P + +  +  ++  ++EAIQ Y+++L+YN TGTQFF IK +R L  LM+ AKE+   +LPIKCLEAVILGIYLTN +  +ERF + F+S + G  F H+VLG+YS G +GA+GMSRRE+LMFKP+ F +L+DL+  +  AY+   H+L +V IG+ +SHD  S+E I WK  +I ++ +S  + ++E+E+++R +R
Sbjct:   28 GVPFYVNRGGLPVDEETWERMWRHVARIHP-NGEGLAKEIRSAADLPKIP-IPSVPSYQLTTTIPQRLEAIQKYIRELQYNHTGTQFFEIKKSRPLTALMDIAKEMTREALPIKCLEAVILGIYLTNNMPGVERFPLSFKSQYSGNHFYHIVLGVYSGGRFGALGMSRREDLMFKPMEFRTLTDLVQEFEGAYRGNWHTLRKVKIGQYVSHDPHSVEQIEWKHSIIDIDKMSKEELRKELERHTRDMR 273
[Close]
BLAST of vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 209.149 bits (531), Expect = 2.330e-65
Identity = 99/197 (50.25%), Postives = 136/197 (69.04%), Query Frame = 2 
Query:  215 PEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
            P VP    +++ +S  +  +Q YMK L+YN TGTQFF IK +R L GLME+A+E+I  SLPIKCLEAVILGIYLTNG++ LERF I F++ F G  F HVVLG+Y NG YG++GMSRR++LM KPL   +L DL+  +  +YQ+  H+L +V IG  + HD    +PI WK +V+  + L     K+E+EK+ R ++
Sbjct:    5 PAVP-TFRASMSVSDWLLTVQKYMKALQYNHTGTQFFEIKKSRPLCGLMETAREMIRESLPIKCLEAVILGIYLTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMK 200
[Close]
BLAST of vasohibin-2 vs. Ensembl Medaka
Match: vash2 (vasohibin 2 [Source:NCBI gene;Acc:101157344])

HSP 1 Score: 139.043 bits (349), Expect = 3.874e-38
Identity = 78/247 (31.58%), Postives = 121/247 (48.99%), Query Frame = 2 
Query:   68 NIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESIL-KQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLR 805
             +QF +N  GFP++  ++ RM      L+ E  E +  I    ++ +   P VP    +++ +S  +  +Q YMK L Y                                            LTNG++ LERF I F++ F G  F HVVLG+Y NG YG++GMSRR++LM KPL   +L DL+  +  +YQ+  H+L +V IG  + HD    +PI WK +V+  + L     K+E+EK+ R ++
Sbjct:   30 GVQFYVNRSGFPIDSSTWDRMWTHVAALHPEGQEMVTRIRNASYLPKHPVPAVP-TFRASMSVSDWLLTVQKYMKALHY--------------------------------------------LTNGMTSLERFPISFKTHFSGHCFHHVVLGVYCNGRYGSLGMSRRQDLMDKPLTHRTLGDLVAEFESSYQKYQHTLAKVKIGLYVPHDPHVFQPIEWKYLVLNASRLGAEDMKKELEKHGRDMK 231
[Close]
BLAST of vasohibin-2 vs. Planmine SMEST
Match: SMESG000072424.1 (SMESG000072424.1)

HSP 1 Score: 646.736 bits (1667), Expect = 0.000e+0
Identity = 317/318 (99.69%), Postives = 318/318 (100.00%), Query Frame = 2 
Query:   41 MENINEAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKPQALKDSTIIYFQRIRSGSQLKNRSKSTECIRV 994
            MENINEAFKNIQFIINNGGFPLNE+SFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKPQALKDSTIIYFQRIRSGSQLKNRSKSTECIRV
Sbjct:    1 MENINEAFKNIQFIINNGGFPLNEISFMRMIEFSKYLNSEDIESIESILKQHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKPQALKDSTIIYFQRIRSGSQLKNRSKSTECIRV 318
[Close]
BLAST of vasohibin-2 vs. Planmine SMEST
Match: SMESG000069763.1 (SMESG000069763.1)

HSP 1 Score: 178.718 bits (452), Expect = 1.321e-53
Identity = 102/263 (38.78%), Postives = 161/263 (61.22%), Query Frame = 2 
Query:   77 FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQ-HVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPR 862
            +++N G FPLN  ++  +I F+   N  D   I+ +LK+ ++ QK  P+VP + +    +  KI  +Q ++ +LEYN+TG QFF I   +++  LM+ AK+II+ SLPIKCLEA+ILGIYLTN +  +ERF IGF S F+G+ +KH+VLGLY+N  +G+IG+SRR  LM+KPL + SL DL+  + K Y++  H L    +  +I H +   + + W+ + I    L+     +++  YS  +  +    GS ++  L   PR
Sbjct:    4 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVP-VFHQFQSIEEKIFLVQSFLNQLEYNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPR 265
[Close]
BLAST of vasohibin-2 vs. Planmine SMEST
Match: SMESG000069763.1 (SMESG000069763.1)

HSP 1 Score: 163.696 bits (413), Expect = 5.150e-48
Identity = 98/263 (37.26%), Postives = 151/263 (57.41%), Query Frame = 2 
Query:   77 FIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILKQ-HVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTNRNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIFKGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAYQQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKYSRKLRKQAAIRGSIQQHYLPFLPR 862
            +++N G FPLN  ++  +I F+   N  D   I+ +LK+ ++ QK  P+VP     +  L               YN+TG QFF I   +++  LM+ AK+II+ SLPIKCLEA+ILGIYLTN +  +ERF IGF S F+G+ +KH+VLGLY+N  +G+IG+SRR  LM+KPL + SL DL+  + K Y++  H L    +  +I H +   + + W+ + I    L+     +++  YS  +  +    GS ++  L   PR
Sbjct:    4 YLVNEGDFPLNVRTWDELINFAISKNPVDRNKIKDLLKKTNLIQKGLPQVPVFHQFHFIL---------------YNYTGMQFFKINKFKSILSLMDEAKKIISSSLPIKCLEAIILGIYLTNDLESVERFGIGFISQFEGVEYKHIVLGLYANQRFGSIGLSRRSNLMYKPLIYKSLYDLLKEFKKCYEEDKHLLFVNYMSSSIEHHAFVSDVVNWQLLNINYLKLNEETIVKQLNSYSDYISHKPERMGSKKRIELADKPR 251
The following BLAST results are available for this feature:
BLAST of vasohibin-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
VASH21.569e-6844.35vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723][more]
VASH17.460e-6842.74vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964][more]
VASH22.066e-6550.25vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723][more]
VASH22.066e-6550.25vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723][more]
VASH24.955e-6453.59vasohibin 2 [Source:HGNC Symbol;Acc:HGNC:25723][more]
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BLAST of vasohibin-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of vasohibin-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of vasohibin-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
VASH13.787e-6841.60vasohibin 1 [Source:NCBI gene;Acc:100001748][more]
vash25.928e-6539.22vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355][more]
vash25.928e-6539.22vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355][more]
vash21.520e-6441.70vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355][more]
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BLAST of vasohibin-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
serinc53.044e-6742.86serine incorporator 5 [Source:Xenbase;Acc:XB-GENE-... [more]
mios7.617e-6643.09missing oocyte, meiosis regulator, homolog [Source... [more]
mios2.747e-3330.08missing oocyte, meiosis regulator, homolog [Source... [more]
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BLAST of vasohibin-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Vash22.411e-6843.95vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826][more]
Vash22.411e-6843.95vasohibin 2 [Source:MGI Symbol;Acc:MGI:2444826][more]
Vash18.557e-6843.55vasohibin 1 [Source:MGI Symbol;Acc:MGI:2442543][more]
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BLAST of vasohibin-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q86V25|VASH2_HUMAN7.537e-6844.35Tubulinyl-Tyr carboxypeptidase 2 OS=Homo sapiens O... [more]
sp|Q8C5G2|VASH2_MOUSE1.687e-6743.95Tubulinyl-Tyr carboxypeptidase 2 OS=Mus musculus O... [more]
sp|Q7L8A9|VASH1_HUMAN3.583e-6742.74Tubulinyl-Tyr carboxypeptidase 1 OS=Homo sapiens O... [more]
sp|Q8C1W1|VASH1_MOUSE5.986e-6743.55Tubulinyl-Tyr carboxypeptidase 1 OS=Mus musculus O... [more]
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BLAST of vasohibin-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267DDW99.280e-7043.90Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267DDU81.028e-6942.81Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267H6J23.275e-6943.90Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267DS334.477e-6943.90Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A3B3H8672.260e-6843.54Vasohibin 2 OS=Oryzias latipes OX=8090 GN=vash2 PE... [more]
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BLAST of vasohibin-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
VASH13.386e-6945.16vasohibin 1 [Source:NCBI gene;Acc:103022300][more]
VASH11.058e-6541.64vasohibin 1 [Source:NCBI gene;Acc:103022300][more]
vash22.935e-6542.35vasohibin 2 [Source:NCBI gene;Acc:103025056][more]
vash26.405e-5237.60vasohibin 2 [Source:NCBI gene;Acc:103025056][more]
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BLAST of vasohibin-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
vash24.800e-5443.78vasohibin 2 [Source:ZFIN;Acc:ZDB-GENE-041014-355][more]
VASH13.158e-4836.54vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964][more]
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BLAST of vasohibin-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of vasohibin-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO402304.603e-5947.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of vasohibin-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
vash28.508e-7243.54vasohibin 2 [Source:NCBI gene;Acc:101157344][more]
vash23.003e-7144.94vasohibin 2 [Source:NCBI gene;Acc:101157344][more]
VASH19.798e-6741.94vasohibin 1 [Source:NCBI gene;Acc:101166671][more]
vash22.330e-6550.25vasohibin 2 [Source:NCBI gene;Acc:101157344][more]
vash23.874e-3831.58vasohibin 2 [Source:NCBI gene;Acc:101157344][more]
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BLAST of vasohibin-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000072424.10.000e+099.69SMESG000072424.1[more]
SMESG000069763.11.321e-5338.78SMESG000069763.1[more]
SMESG000069763.15.150e-4837.26SMESG000069763.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001975 ID=SMED30001975|Name=vasohibin-2|organism=Schmidtea mediterranea sexual|type=transcript|length=1106bp
CCGATCTCCTAGATATTAAAGCCTGAAAGATTCAATTCATATGGAAAATA
TAAATGAGGCTTTTAAGAATATTCAATTTATAATTAACAATGGTGGCTTT
CCTTTGAATGAAATGTCATTTATGCGAATGATTGAATTTTCTAAATATTT
AAATTCCGAAGACATTGAAAGTATAGAAAGTATTTTGAAACAACACGTTA
ATCAAAAGAAATATCCGGAAGTTCCGCGAATGCTAAATAGCAACATTAAA
TTATCAGTAAAAATTGAAGCTATTCAAGACTATATGAAAAAATTAGAATA
CAATTTCACCGGTACACAATTTTTCCCAATAAAAACCAATCGCAACTTAA
ATGGATTAATGGAAAGTGCCAAAGAAATAATCAACTATTCCCTTCCAATT
AAATGCCTCGAAGCAGTAATTCTAGGAATATACCTGACAAATGGGATTTC
CCAATTAGAACGATTTACTATTGGATTCAGATCTATTTTCAAAGGACTCG
TTTTTAAACACGTAGTTTTAGGGTTGTATTCAAATGGGCTTTATGGTGCT
ATTGGGATGAGCCGACGAGAGGAACTCATGTTCAAGCCTTTGCATTTTAA
TTCTTTAAGTGACCTCATAATTAGCTATGTTAAAGCCTATCAGCAGCTGA
ATCATAGCTTGGTGCGAGTTTCAATAGGAGAAAATATTTCACATGATTCT
TGCAGTTTAGAACCAATTTTCTGGAAAGGAGTTGTGATACGGTTGAACGG
TCTGAGTGTTAACCAATTTAAAGAGGAAATAGAAAAATATTCCAGAAAGC
TTAGAAAACAGGCTGCTATACGGGGGTCAATACAGCAACATTATCTGCCC
TTTCTTCCCAGGTGTAATCTAGATTCTACTGCAGCCTTACGAAAACCTCA
AGCTCTCAAGGATTCTACTATTATTTATTTTCAGCGTATCAGGAGTGGAT
CTCAATTAAAAAACAGATCCAAGTCAACAGAATGTATTCGAGTCTAAATA
CCTGGACCAGAAATTCTTTCAGCATTGTCTTGTCTATATTAAATGGCGCA
AAAAATGTAGTATCAAAAGAAATTCTCAAAAATAAATTTTTTTTTCTCAA
AAAAAA
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protein sequence of SMED30001975-orf-1

>SMED30001975-orf-1 ID=SMED30001975-orf-1|Name=SMED30001975-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=319bp
MENINEAFKNIQFIINNGGFPLNEMSFMRMIEFSKYLNSEDIESIESILK
QHVNQKKYPEVPRMLNSNIKLSVKIEAIQDYMKKLEYNFTGTQFFPIKTN
RNLNGLMESAKEIINYSLPIKCLEAVILGIYLTNGISQLERFTIGFRSIF
KGLVFKHVVLGLYSNGLYGAIGMSRREELMFKPLHFNSLSDLIISYVKAY
QQLNHSLVRVSIGENISHDSCSLEPIFWKGVVIRLNGLSVNQFKEEIEKY
SRKLRKQAAIRGSIQQHYLPFLPRCNLDSTAALRKPQALKDSTIIYFQRI
RSGSQLKNRSKSTECIRV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR028131VASH1
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005576extracellular region
Vocabulary: biological process
TermDefinition
GO:0045765regulation of angiogenesis
GO:0000768syncytium formation by plasma membrane fusion
GO:0001938positive regulation of endothelial cell proliferation
GO:0045026plasma membrane fusion
GO:0045766positive regulation of angiogenesis
GO:0060674placenta blood vessel development
GO:0060711labyrinthine layer development
GO:0060716labyrinthine layer blood vessel development
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 240..260
IPR028131Tubulinyl-Tyr carboxypeptidasePFAMPF14822Vasohibincoord: 12..255
e-value: 3.3E-88
score: 295.1
IPR028131Tubulinyl-Tyr carboxypeptidasePANTHERPTHR15750FAMILY NOT NAMEDcoord: 33..282