Acid-sensing ion channel 1C

Overview
NameAcid-sensing ion channel 1C
Smed IDSMED30001910
Length (bp)1848
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Acid-sensing ion channel 1C (SMED30001910) t-SNE clustered cells

Violin plots show distribution of expression levels for Acid-sensing ion channel 1C (SMED30001910) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Acid-sensing ion channel 1C (SMED30001910) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Acid-sensing ion channel 1C (SMED30001910) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001910

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30001910h1SMcG0021133 dd_Smed_v4_19727_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001910h1SMcG0021133 dd_Smed_v4_19727_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30001910h1SMcG0021133 dd_Smed_v4_19727_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 56.225 bits (134), Expect = 1.337e-7
Identity = 72/348 (20.69%), Postives = 144/348 (41.38%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYP-FGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYIL---DAYSQIDLRITSKQHLNVN-NRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFS-VNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I++C +    C+Y++F T   YP +G C+ FN             +   + S  P  +  +   +D+G+   V PF   T   G+ +M+H++ ++PFI +  I       + I + +   Q +    + C ++       + + + +T +S +   C+    Q ++++NC C    +P   +P   +YC +  F    H    L+ + A+  E  +  C ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  219 ILACLFGAEPCNYRNF-TSIFYPHYGNCYIFNWGM----------TEKALPSANPGTEFGLKLILDIGQEDYV-PFLAST--AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQA--CLRSCFQDHMIRNCNCGHYLYP---LPRGEKYCNNRDFPDWAHCYSDLQMSVAQ-RETCIGMC-KESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNITLSR----------------KGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 506
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 56.225 bits (134), Expect = 1.425e-7
Identity = 72/348 (20.69%), Postives = 144/348 (41.38%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYP-FGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYIL---DAYSQIDLRITSKQHLNVN-NRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFS-VNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I++C +    C+Y++F T   YP +G C+ FN             +   + S  P  +  +   +D+G+   V PF   T   G+ +M+H++ ++PFI +  I       + I + +   Q +    + C ++       + + + +T +S +   C+    Q ++++NC C    +P   +P   +YC +  F    H    L+ + A+  E  +  C ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  291 ILACLFGAEPCNYRNF-TSIFYPHYGNCYIFNWGM----------TEKALPSANPGTEFGLKLILDIGQEDYV-PFLAST--AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQA--CLRSCFQDHMIRNCNCGHYLYP---LPRGEKYCNNRDFPDWAHCYSDLQMSVAQ-RETCIGMC-KESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNITLSR----------------KGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 578
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 56.225 bits (134), Expect = 1.639e-7
Identity = 72/348 (20.69%), Postives = 144/348 (41.38%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYP-FGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYIL---DAYSQIDLRITSKQHLNVN-NRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFS-VNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I++C +    C+Y++F T   YP +G C+ FN             +   + S  P  +  +   +D+G+   V PF   T   G+ +M+H++ ++PFI +  I       + I + +   Q +    + C ++       + + + +T +S +   C+    Q ++++NC C    +P   +P   +YC +  F    H    L+ + A+  E  +  C ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  246 ILACLFGAEPCNYRNF-TSIFYPHYGNCYIFNWGM----------TEKALPSANPGTEFGLKLILDIGQEDYV-PFLAST--AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQA--CLRSCFQDHMIRNCNCGHYLYP---LPRGEKYCNNRDFPDWAHCYSDLQMSVAQ-RETCIGMC-KESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNITLSR----------------KGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 533
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Celegans
Match: flr-1 (FLR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGI5])

HSP 1 Score: 48.9062 bits (115), Expect = 9.618e-6
Identity = 60/261 (22.99%), Postives = 95/261 (36.40%), Query Frame = 2 
Query:   86 HFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPIL--TNVIQNYQRFIFPDISICFTNPI--------------------YYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMG---HDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFD--DVTIPGGILVMIHDEHTFPFIGNSY 787
             F   +T+HGL +I  +     R+FW+ +       F+I+  YLL  Y   P L  TN I      +FP+++IC  NP+                    Y+    +  HK      + +L    N         N+  +L              + +SCS+     H+C  +H  T  +   GVC   ++     +     N F              ++ V  G N   D  D  D     G L+M+H+   +P I NSY
Sbjct:   21 EFSGLTTYHGLVRIYNSNTWPSRIFWVVVVLSCLSLFMIHSGYLLLGYHAKPTLFQTNTIVPMNGLLFPEVTICNLNPLNTTKLEELNISKSTWTYIFGYFDEITTSEHKSTKLGEEQFLEIMNNYQELTKQEFNVKNFL-----KSVSKSCEETFISCSFGREKLHNCC-EHVTT-EMTEVGVCFRLSNVNKKYRQWYSGNGFG-------------WEFVLNGNNEIDDHADSLDFEPDRGFLIMVHESEKYPKI-NSY 260
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Celegans
Match: flr-1 (FLR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGI5])

HSP 1 Score: 48.9062 bits (115), Expect = 9.618e-6
Identity = 60/261 (22.99%), Postives = 95/261 (36.40%), Query Frame = 2 
Query:   86 HFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPIL--TNVIQNYQRFIFPDISICFTNPI--------------------YYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMG---HDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFD--DVTIPGGILVMIHDEHTFPFIGNSY 787
             F   +T+HGL +I  +     R+FW+ +       F+I+  YLL  Y   P L  TN I      +FP+++IC  NP+                    Y+    +  HK      + +L    N         N+  +L              + +SCS+     H+C  +H  T  +   GVC   ++     +     N F              ++ V  G N   D  D  D     G L+M+H+   +P I NSY
Sbjct:   21 EFSGLTTYHGLVRIYNSNTWPSRIFWVVVVLSCLSLFMIHSGYLLLGYHAKPTLFQTNTIVPMNGLLFPEVTICNLNPLNTTKLEELNISKSTWTYIFGYFDEITTSEHKSTKLGEEQFLEIMNNYQELTKQEFNVKNFL-----KSVSKSCEETFISCSFGREKLHNCC-EHVTT-EMTEVGVCFRLSNVNKKYRQWYSGNGFG-------------WEFVLNGNNEIDDHADSLDFEPDRGFLIMVHESEKYPKI-NSY 260
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Zebrafish
Match: asic4b (acid-sensing (proton-gated) ion channel family member 4b [Source:NCBI gene;Acc:407667])

HSP 1 Score: 56.6102 bits (135), Expect = 5.998e-8
Identity = 63/248 (25.40%), Postives = 100/248 (40.32%), Query Frame = 2 
Query:  110 HGLSQIARARKIRQRV-FWITICGGA---SLG-FLINIYYLLDKYLETPILTNVIQNYQR-FIFPDISICFTN----------PIYY-------PPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQ---ITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            HGL   ARA    +R+ F  T+ G A   SLG FL    +    YLE P L  + +  +R   FP I++C  N           IY+       PPK  + H+          Y   NM   F                  GH     + SC++ G +CS + F   +   +G C+TFN  K   K +R+  + +G++ +    Q   + +++             ++ T+  GI V IH ++  P+I
Sbjct:   54 HGL---ARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHR-----PSELQYPPPNMLDIFQR---------------TGHQLEDMLKSCNFSGQNCSSEDFSVVYTR-YGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRET-----------NETTLEAGIRVQIHSQNEPPYI 266
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Zebrafish
Match: asic1a (acid-sensing (proton-gated) ion channel 1a [Source:NCBI gene;Acc:791696])

HSP 1 Score: 53.1434 bits (126), Expect = 7.784e-7
Identity = 65/253 (25.69%), Postives = 98/253 (38.74%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDK---YLETPILTNVIQ-NYQRFIFPDISICFTNPIYYPP--------------------KDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            F H ST HG+S I    KI  +     +   +SL FL  +Y  +D+   YLE P +T + +      +FP ++IC  N I +                      +  EAH L+ E+    L  K +   F     N+ E+   T     GH     ++SC + G  C  + F       +G C+TFNS +     +           +    Q   Y  V  GE+      D+ +   GI V IH +   PFI
Sbjct:   26 FAHTSTLHGISHIFSYEKITAKCCLWVVFFLSSLTFL--MYVCIDRIQFYLEYPHVTKLDEITTPVMVFPAVTICNLNSIRFSRITRNDLYHAGELLALLNSRHEVREAH-LVEESVMEVLKSKTDFRSFKPRHFNMWEFYNRT-----GHDIKDMLLSCQFRGSPCRPEDFSVVFTR-YGKCYTFNSGETGPPRVSVKGGMGNGLEIMLDIQQDEYLPV-WGES------DESSFEAGIKVQIHSQDEPPFI 262
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966])

HSP 1 Score: 51.2174 bits (121), Expect = 4.130e-6
Identity = 65/261 (24.90%), Postives = 101/261 (38.70%), Query Frame = 2 
Query:   80 VLHFCHRSTFHGLSQIARARKIR-QRVFWITICGGASLGFLINIYYLLDK---YLETPILTNVIQ-NYQRFIFPDISIC-----------------------FTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDM-GENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            V  F   ST HGL+ I    +   +R+ W+ +C   SL  L+  Y   ++   Y E P +T + + +  R IFP ++ C                         N  Y  P    A + +ME  Q+    K N   F     N+ E+      D  GH     ++SC Y G +CS   F       +G C+TFNS +     +      +G   ++    I   + + + GE       D+ +   GI V IH +   PFI
Sbjct:   20 VQAFASGSTLHGLAHIFTYERFSCRRLIWV-LCFLGSLSLLL--YVCTERIIYYFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQD----KANFRNFKPKPFNMREFY-----DRTGHDIREMLLSCKYRGEECSVDDF-VPVFTRYGKCYTFNSGRNGRSPLVTTKGGTG-NGLELMLDIQQDEYLPVWGET------DETSFEAGIKVQIHSQDEPPFI 260
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966])

HSP 1 Score: 51.2174 bits (121), Expect = 4.368e-6
Identity = 86/361 (23.82%), Postives = 139/361 (38.50%), Query Frame = 2 
Query:   80 VLHFCHRSTFHGLSQIARARKIR-QRVFWITICGGASLGFLINIYYLLDK---YLETPILTNVIQ-NYQRFIFPDISIC-----------------------FTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFE---TRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDM-GENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITI-QIN-----VMKNCQCIWQHFPTI---LVPPSTRYCL 1039
            V  F   ST HGL+ I    +   +R+ W+ +C   SL  L+  Y   ++   Y E P +T + + +  R IFP ++ C                         N  Y  P    A + +ME  Q+    K N   F     N+ E+      D  GH     ++SC Y G +CS   F    TR    +G C+TFNS +     +      +G   ++    I   + + + GE       D+ +   GI V IH +   PFI          Q+   +       V+  C+  +  Y      + KS+A  ++  D   I+  +I+     +++NC C   H P I   LV     +C+
Sbjct:   17 VQAFASGSTLHGLAHIFTYERFSCRRLIWV-LCFLGSLSLLL--YVCTERIIYYFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQD----KANFRNFKPKPFNMREFY-----DRTGHDIREMLLSCKYRGEECSVDDFVPVFTR----YGKCYTFNSGRNGRSPLVTTKGGTG-NGLELMLDIQQDEYLPVWGET------DETSFEAGIKVQIHSQDEPPFI---------DQLGFGVAPGFQTFVS--CQEQRLTYLPPPWGDCKSSAMDSEFFDTYSISACRIDCETRYLVENCNCRMVHMPGICYFLVEKDNDFCV 343
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966])

HSP 1 Score: 50.8322 bits (120), Expect = 6.398e-6
Identity = 65/261 (24.90%), Postives = 101/261 (38.70%), Query Frame = 2 
Query:   80 VLHFCHRSTFHGLSQIARARKIR-QRVFWITICGGASLGFLINIYYLLDK---YLETPILTNVIQ-NYQRFIFPDISIC-----------------------FTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDM-GENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            V  F   ST HGL+ I    +   +R+ W+ +C   SL  L+  Y   ++   Y E P +T + + +  R IFP ++ C                         N  Y  P    A + +ME  Q+    K N   F     N+ E+      D  GH     ++SC Y G +CS   F       +G C+TFNS +     +      +G   ++    I   + + + GE       D+ +   GI V IH +   PFI
Sbjct:   17 VQAFASGSTLHGLAHIFTYERFSCRRLIWV-LCFLGSLSLLL--YVCTERIIYYFEYPHVTKLDEISTPRMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLNNRYELPDSQLADEKVMEILQD----KANFRNFKPKPFNMREFY-----DRTGHDIREMLLSCKYRGEECSVDDF-VPVFTRYGKCYTFNSGRNGRSPLVTTKGGTG-NGLELMLDIQQDEYLPVWGET------DETSFEAGIKVQIHSQDEPPFI 257
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Mouse
Match: Asic5 (acid-sensing (proton-gated) ion channel family member 5 [Source:MGI Symbol;Acc:MGI:1929259])

HSP 1 Score: 55.4546 bits (132), Expect = 1.346e-7
Identity = 62/264 (23.48%), Postives = 119/264 (45.08%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNV-IQNYQRFIFPDISICFTN----------PIYYPPKDSEAHKL-LMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIY-PFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPG----GILVMIHD---EHTFPFIGNSYILDAYSQIDLR 820
            F   ++FHG+  IA+ +   ++V W+ +  G+    +  IY  L  Y   P  T++ +Q  ++  FP +++C  N           I +   D  +  L L E   N     + +D F +N  N +   F+    FY ++   ++V C + G  CS K F  +H++  +G C TFN  +  +++  K+ S SG             + + +  + + + F D  +PG    G++ +IH    E  F  +G S  +  ++++ +R
Sbjct:   41 FAMSTSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLNRFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLD-FVTNHQNFSITEFVKNNGFYLNN--DTLVHCEFFGKTCSPKDF--KHVFTEYGNCFTFNYGE-NIQNKNKV-SVSG-------------RGLKLLLDVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIR 284
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Mouse
Match: Asic5 (acid-sensing (proton-gated) ion channel family member 5 [Source:MGI Symbol;Acc:MGI:1929259])

HSP 1 Score: 54.299 bits (129), Expect = 3.182e-7
Identity = 61/260 (23.46%), Postives = 118/260 (45.38%), Query Frame = 2 
Query:  101 STFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNV-IQNYQRFIFPDISICFTN----------PIYYPPKDSEAHKL-LMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIY-PFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPG----GILVMIHD---EHTFPFIGNSYILDAYSQIDLR 820
            ++FHG+  IA+ +   ++V W+ +  G+    +  IY  L  Y   P  T++ +Q  ++  FP +++C  N           I +   D  +  L L E   N     + +D F +N  N +   F+    FY ++   ++V C + G  CS K F  +H++  +G C TFN  +  +++  K+ S SG             + + +  + + + F D  +PG    G++ +IH    E  F  +G S  +  ++++ +R
Sbjct:    3 TSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLNRFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLD-FVTNHQNFSITEFVKNNGFYLNN--DTLVHCEFFGKTCSPKDF--KHVFTEYGNCFTFNYGE-NIQNKNKV-SVSG-------------RGLKLLLDVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIR 242
[Close]
BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Match: sp|O97742|SCNNB_RABIT (Amiloride-sensitive sodium channel subunit beta OS=Oryctolagus cuniculus OX=9986 GN=SCNN1B PE=2 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 3.843e-8
Identity = 76/356 (21.35%), Postives = 143/356 (40.17%), Query Frame = 2 
Query:  464 GHHAWGSIVSCSYMGHDCSYKHFETRHIYP-FGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITS-----KQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDC-LKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            G+ A   I++C +    CSY++F T   YP +G C+ FN             +   + S  P  +  +   +D+G+   V PF   T   G+ +M+H++ ++PFI    + DA S  +  I       ++     + C ++       +L+ + +T +S +   C++   Q  ++ +CQC    +P   +P    YC    F       C L    +E   E   +  ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  240 GYSAERLILACLFGAEPCSYRNF-TSIFYPDYGNCYVFNWGM----------TEKALPSANPGTEFGLKLILDIGQEDYV-PFLAST--AGVRLMLHEQRSYPFIREEGV-DAMSGTETSIGVLVDKLQRKGEPYSPCTVNGSDVPVQNLYGSYNTTYSIQA--CLHSCFQTQMIASCQCGHYLYP---LPRGQEYCNSRDFP--DWAPCYLALRMSEAERETCIRMCKESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNVTLSR----------------KGVVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 534
[Close]
BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Match: sp|Q95165|SCNNB_CANLF (Amiloride-sensitive sodium channel subunit beta OS=Canis lupus familiaris OX=9615 GN=SCNN1B PE=3 SV=2)

HSP 1 Score: 58.9214 bits (141), Expect = 1.111e-7
Identity = 72/352 (20.45%), Postives = 143/352 (40.62%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITS-----KQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYC-----LDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I++C +    CSY++F +     +G C+ FN             +   + S  P  +  +   +D+G+   V PF  +T   G  +M+H++ ++PFI +  I  A S  +  I       ++     ++C ++       +L+ + +T +S +   C+    Q ++++NC C    +P   +P   RYC      D  +  +HL+  + +    I       C ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  247 ILACLFGAEPCSYRNFTSIFHPDYGNCYIFNWGM----------TEKALPSANPGAEFGLKLILDIGQEDYV-PF--LTSTAGARLMLHEQRSYPFIKDEGIY-AMSGTETSIGVLVDRLERKGEPYSQCTVNGSDVPVRNLYSDYNTTYSIQA--CIRSCFQDHMIQNCSCAHYLYP---LPRGERYCNNREFPDWAYCYSHLRMSVAQRETCIN-----MC-KESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNITLSR----------------KGVVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 534
[Close]
BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Match: sp|Q708S3|ASI4B_DANRE (Acid-sensing ion channel 4-B OS=Danio rerio OX=7955 GN=asic4b PE=2 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 4.528e-7
Identity = 63/248 (25.40%), Postives = 100/248 (40.32%), Query Frame = 2 
Query:  110 HGLSQIARARKIRQRV-FWITICGGA---SLG-FLINIYYLLDKYLETPILTNVIQNYQR-FIFPDISICFTN----------PIYY-------PPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQ---ITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            HGL   ARA    +R+ F  T+ G A   SLG FL    +    YLE P L  + +  +R   FP I++C  N           IY+       PPK  + H+          Y   NM   F                  GH     + SC++ G +CS + F   +   +G C+TFN  K   K +R+  + +G++ +    Q   + +++             ++ T+  GI V IH ++  P+I
Sbjct:   54 HGL---ARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHR-----PSELQYPPPNMLDIFQR---------------TGHQLEDMLKSCNFSGQNCSSEDFSVVYTR-YGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRET-----------NETTLEAGIRVQIHSQNEPPYI 266
[Close]
BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Match: sp|P51168|SCNNB_HUMAN (Amiloride-sensitive sodium channel subunit beta OS=Homo sapiens OX=9606 GN=SCNN1B PE=1 SV=2)

HSP 1 Score: 56.225 bits (134), Expect = 7.871e-7
Identity = 72/348 (20.69%), Postives = 144/348 (41.38%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYP-FGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYIL---DAYSQIDLRITSKQHLNVN-NRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFS-VNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I++C +    C+Y++F T   YP +G C+ FN             +   + S  P  +  +   +D+G+   V PF   T   G+ +M+H++ ++PFI +  I       + I + +   Q +    + C ++       + + + +T +S +   C+    Q ++++NC C    +P   +P   +YC +  F    H    L+ + A+  E  +  C ++ C+   ++  IS + +P+         W+  +   ER++                   ST +TL++                +  + L +    F    +EE+    I  LLS++GG  G W+G S
Sbjct:  246 ILACLFGAEPCNYRNF-TSIFYPHYGNCYIFNWGM----------TEKALPSANPGTEFGLKLILDIGQEDYV-PFLAST--AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQA--CLRSCFQDHMIRNCNCGHYLYP---LPRGEKYCNNRDFPDWAHCYSDLQMSVAQ-RETCIGMC-KESCNDTQYKMTISMADWPSEASE----DWIFHVLSQERDQ-------------------STNITLSR----------------KGIVKLNIYFQEFNYRTIEESAANNIVWLLSNLGGQFGFWMGGS 533
[Close]
BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Match: sp|Q9R0Y1|ASIC5_MOUSE (Acid-sensing ion channel 5 OS=Mus musculus OX=10090 GN=Asic5 PE=2 SV=1)

HSP 1 Score: 55.4546 bits (132), Expect = 9.415e-7
Identity = 62/264 (23.48%), Postives = 119/264 (45.08%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNV-IQNYQRFIFPDISICFTN----------PIYYPPKDSEAHKL-LMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIY-PFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPG----GILVMIHD---EHTFPFIGNSYILDAYSQIDLR 820
            F   ++FHG+  IA+ +   ++V W+ +  G+    +  IY  L  Y   P  T++ +Q  ++  FP +++C  N           I +   D  +  L L E   N     + +D F +N  N +   F+    FY ++   ++V C + G  CS K F  +H++  +G C TFN  +  +++  K+ S SG             + + +  + + + F D  +PG    G++ +IH    E  F  +G S  +  ++++ +R
Sbjct:   41 FAMSTSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLNRFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLD-FVTNHQNFSITEFVKNNGFYLNN--DTLVHCEFFGKTCSPKDF--KHVFTEYGNCFTFNYGE-NIQNKNKV-SVSG-------------RGLKLLLDVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIR 284
[Close]
BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Match: A0A0R3SIE1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS4705 PE=3 SV=1)

HSP 1 Score: 405.601 bits (1041), Expect = 1.380e-129
Identity = 190/478 (39.75%), Postives = 301/478 (62.97%), Query Frame = 2 
Query:   83 LHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADL-ERNEMKYFGQSELRTKALKM-INASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            L F  RST HGL+ +A+AR  ++R+FW+ I   A +GF  N+++L++KY++ P+LTNV+ +   FI+PD++ C  NPIY+PPK++   K ++   + +  +KK+  P   +R+ LA+YLF+ +  FY H  W +IV C YM   CSYKHF+ + ++P+G C+TFN+TK++    R+I + +     +P F+I VYKA+DM E + +DP   V +P GIL+MIH+  T+P IG+S I+D  +QI+LR+T  +HL    +C   +E  +Y++   N+S  F +   DC+   +Q  + +NC C     P +    +  +C   + + + ++ C       +  ++   C++D+C+H   + V+  +KFPA+ ER T+ +WL++LA L ER + +Y G+S++   AL     A+  +T+          LL+ DFV+RNFMMLR+VP S FMD+VEET EYP SRLLSD+GGCVGLW+GAS
Sbjct:   80 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISIAALVGFFFNMFFLIEKYIQVPVLTNVLHDSDNFIYPDVTFCNINPIYFPPKETAEFKRMIAAIEKFKKFKKSTHPHV-HRLELADYLFVERNTFYVHPKWLTIVECQYMQTPCSYKHFDEKILWPYGACYTFNATKMLNNMTREIITRNRFNRFRPDFKIIVYKALDMPEEYRMDPHGSVNVPSGILLMIHEPGTYPHIGHSSIVDECAQIELRMTYVKHLAKLGKCVPEREHISYVNTATNESQNFLSSQSDCLDAAVQTALAENCGCQMHTMPVMYRYNNLPFCFSDSLNFSFIESCFSNVSNAVDRQH---CFRDVCEHFTIDRVVVHAKFPAIAERHTYQNWLRLLARLEEREKAQYRGKSDIAKLALNADFTANPNLTIKDIFASGNTSLLNLDFVNRNFMMLRIVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGAS 553
[Close]
BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Match: A0A564Z6I1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS12764 PE=3 SV=1)

HSP 1 Score: 405.601 bits (1041), Expect = 1.729e-129
Identity = 190/478 (39.75%), Postives = 301/478 (62.97%), Query Frame = 2 
Query:   83 LHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADL-ERNEMKYFGQSELRTKALKM-INASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            L F  RST HGL+ +A+AR  ++R+FW+ I   A +GF  N+++L++KY++ P+LTNV+ +   FI+PD++ C  NPIY+PPK++   K ++   + +  +KK+  P   +R+ LA+YLF+ +  FY H  W +IV C YM   CSYKHF+ + ++P+G C+TFN+TK++    R+I + +     +P F+I VYKA+DM E + +DP   V +P GIL+MIH+  T+P IG+S I+D  +QI+LR+T  +HL    +C   +E  +Y++   N+S  F +   DC+   +Q  + +NC C     P +    +  +C   + + + ++ C       +  ++   C++D+C+H   + V+  +KFPA+ ER T+ +WL++LA L ER + +Y G+S++   AL     A+  +T+          LL+ DFV+RNFMMLR+VP S FMD+VEET EYP SRLLSD+GGCVGLW+GAS
Sbjct:   80 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISIAALVGFFFNMFFLIEKYIQVPVLTNVLHDSDNFIYPDVTFCNINPIYFPPKETAEFKRMIAAIEKFKKFKKSTHPHV-HRLELADYLFVERNTFYVHPKWLTIVECQYMQTPCSYKHFDEKILWPYGACYTFNATKMLNNMTREIITRNRFNRFRPDFKIIVYKALDMPEEYRMDPHGSVNVPSGILLMIHEPGTYPHIGHSSIVDECAQIELRMTYVKHLAKLGKCVPEREHISYVNTATNESQNFLSSQSDCLDAAVQTALAENCGCQMHTMPVMYRYNNLPFCFSDSLNFSFIESCFSNVSNAVDRQH---CFRDVCEHFTIDRVVVHAKFPAIAERHTYQNWLRLLARLEEREKAQYRGKSDIAKLALNADFTANPNLTIKDIFASGNTSLLNLDFVNRNFMMLRIVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGAS 553
[Close]
BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Match: A0A183SCX1 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS2069 PE=3 SV=1)

HSP 1 Score: 396.741 bits (1018), Expect = 1.081e-127
Identity = 197/477 (41.30%), Postives = 303/477 (63.52%), Query Frame = 2 
Query:   83 LHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMK-YFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            L F  RST HGL+ +A+AR  ++R+FW+ I   +S GF  N+++L++KY++ P+LTNV+ +   FIFPD++ C  NPIY+PP  +   + + EN   +  +K++ +PF + R+ LA+YLF+ +  +Y H  W +IV CSYM   CS +HF+ + I+P+G C+TFN+T++     R+I++ +     +P  +I VYKA++  E +  DP D   +P G+L+MIH+  T+P IG+S I+D  +Q++L++TS  HL    +C   +    Y+++  N+S  F +   DC+   +Q  + K C C     P +       +C  G    + L+ C  K  A +  ++   C+ D+C+H   + VI+ +KFPAV +R T   WL++LADLE  E+K Y G+S+L   ALK +     +TL +A K ++IDLL+ DFV+RNFMMLRVVP+S FMD+VEET EYP SRLLSD+GGCVGLW+GAS
Sbjct:   78 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISLASSFGFFFNLFFLMEKYIQVPVLTNVLHDSDNFIFPDVTFCNVNPIYFPPNGTPEFERIKENIHAFEDFKRSSNPF-AKRLALADYLFIKRNTYYVHPKWLTIVECSYMQTPCSSEHFDEKIIWPYGACYTFNATRMPHNMSREISTRTRYNRFRPDLRIIVYKALEFPEGYRFDPHDSFQVPPGVLLMIHEPGTYPHIGHSGIVDECTQVELKMTSVTHLAKLGKCIPMRSRIAYVNVASNESQTFLSSQSDCLDAEVQSALAKYCGCQMHTMPIMYEYHHQPFCFSGALEPSFLETCFNKATASVDRKH---CFLDVCEHYTIDRVIAHTKFPAVEDRHTEQHWLQLLADLEDRELKQYSGRSDLAKMALKDVPGGN-ITLAEAAKKRQIDLLNIDFVNRNFMMLRVVPDSLFMDRVEETEEYPFSRLLSDIGGCVGLWIGAS 549
[Close]
BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Match: A0A448WRB3 (Uncharacterized protein (Fragment) OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS11667 PE=3 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 1.199e-123
Identity = 189/488 (38.73%), Postives = 302/488 (61.89%), Query Frame = 2 
Query:   56 IWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQ-SELRTKA-LKMINAS-TRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            +  R    ++ F  RSTFHGL+ +A+AR   +R+FW+ I   AS+GF  N+Y+L+ KY++TPILTNV+ + Q FI+PD++ CF N IY+PP++S A++ L+ ++     Y + +    +N++ L++YL+M     Y H AW ++V C Y    C+++HF+ R ++P+G C T N+TK+ MK  R I      +  +P F++ +YKA+D   +F  D  + V +P GI +MIH+  TFP      I++  +Q+D+++T   HL   ++C   ++     D+    S +  A+  DC+   +Q +V   C C+    P         +C +G F++++L DCL ++ A  + E+   C+ DLC+H     V+SQS +P + +R TH  WL++LA +E +E+++FG  S+L  KA L   NA+   M L +  +  R+DLL+ DFV+RNF+MLR+ P+ FFMDKV ET+EYP+S LLSD+GGCVGLW+GAS
Sbjct:   96 VMNRVGTTLIRFSQRSTFHGLNHLAQARSAHRRIFWLAISLFASIGFFTNLYFLIYKYMQTPILTNVLHDAQPFIYPDVTFCFVNSIYFPPRNSSAYQELVRHFSA---YDQLVAKGLNNKIKLSDYLYMQPHANYTHPAWSAVVQCHYQHQPCNWQHFDVRRLWPWGSCFTLNATKMNMK--RDIRHREIKKKFRPDFKLIIYKALDRPADFTRDLHNGVDLPPGIALMIHEPGTFPPRDECAIVNGCTQVDIKMTWVSHLAHLSKCSSKRDILDLFDIGSGTSYSVLARQADCIDTIVQQSVALECHCLIHSLPISNNISHLDFCFNGRFNISYLNDCLLRSQAHFSVEH---CFLDLCEHFSMTRVVSQSSYPGIRDRFTHRDWLRVLAGIEVSELEHFGNTSDLAEKALLPHANATGPPMRLTEVVRQGRVDLLNTDFVERNFLMLRIQPSGFFMDKVLETVEYPLSHLLSDIGGCVGLWIGAS 575
[Close]
BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Match: A0A3P7LUS4 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS5772 PE=3 SV=1)

HSP 1 Score: 384.415 bits (986), Expect = 1.224e-121
Identity = 190/479 (39.67%), Postives = 300/479 (62.63%), Query Frame = 2 
Query:   83 LHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYF-GQSELRTKALKMI--NASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            L F  RST HGL+ +A+AR  ++R+FW+ I   +S GF  N+++L++KYL+ P+LTNV+ +   FIFPD++ C  NPI++PP  +   + + EN + +  +K+  +PF + R+ LA+YLF+ +  +Y H  W +IV CSYM   CS +HF+ + I+P+G C+TFN+T++     R+I++ +     +P  ++ VYKA++  E +  DP D   +P G+L+MIH+  T+P IG+S I+D  +Q++L++TS  HL    +C   +   +Y+++ +N+S  F +   DC+   +Q  + K C C     P +       +C  G      L++C     A +  ++   C+ D+C+H   + VI+ +KFPA+ +R T + WL++LA LE  E  ++ G+S+L   ALK    +     TL +A   ++IDLL+ DFV+RNFMMLRVVP S FMD+VEET EYP SRLLSD+GGCVGLW+GAS
Sbjct:   74 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISLASSFGFFFNLFFLMEKYLQMPVLTNVLHDSDNFIFPDVTFCNVNPIHFPPNGTPEFERIKENIREFEDFKRGPNPF-AQRLALADYLFIKRNTYYVHPKWLTIVECSYMQTPCSSEHFDEKIIWPYGACYTFNATRMPHNMTREISTRTRYNRFRPDLRVIVYKALEFPEGYRFDPHDSFQVPPGVLLMIHEPGTYPHIGHSGIVDECTQVELKMTSVTHLAKLGKCIPIRSRISYVNVAKNESQTFLSSQSDCLDAEVQSALAKYCGCQMHTMPIMYEYHYQPFCFSGALDPTFLENCFNNATASVDRKH---CFLDVCEHYTIDQVIAHTKFPAIEDRHTELHWLQLLARLEARERNHYGGKSDLAKLALKNASRDGGGNWTLAEAVNQRQIDLLNIDFVNRNFMMLRVVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGAS 548
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Sea Lamprey
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 53.9138 bits (128), Expect = 8.636e-8
Identity = 73/350 (20.86%), Postives = 134/350 (38.29%), Query Frame = 2 
Query:  485 IVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYIL---DAYSQIDLRITSKQHLNVN-NRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFES----VISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            I SC +    CS  +F T     +G C  FN  +          + + MQ   P  +  +   + + ++  + PF  +T   G ++M+HD++T+PF+ +  +       + + + +   Q      + C +        +L+    TA+S +   C+    Q  +++ C C +  +P   +PP  +YC +  F+    + C  K + +  EE +  CY  +C     ES     IS S +P+ +       W+  +   ER                              H + RI    +D +  N          F    + E+    I  LLS++GG  G W+G S
Sbjct:  250 IRSCLFSSDTCSATNFTTFFHPMYGNCFIFNWGE----------NETVMQVSNPGVEYGLKLVLSIDQDEYI-PF--LTTIAGAVIMVHDQNTYPFLSDLGVFVKTGVETSVGIEVGQLQRQGAPYSDCTMDGTDLPITNLY--NGTAYSVQA--CLRSCFQTKMIEMCGCGYYLYP---LPPGEKYCQNQNFT--GWRYCYYKLYEQFVEEDM-DCYT-ICKQPCIESEYKMSISMSDWPSQSSE----DWIFHILSKERK-----------------------------HNVSRIFNRKQDIIKLNLFF-----QEFNSMTISESPAQTIVTLLSNLGGQFGFWMGGS 537
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Match: EDO42137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F2])

HSP 1 Score: 76.6406 bits (187), Expect = 9.490e-15
Identity = 110/514 (21.40%), Postives = 207/514 (40.27%), Query Frame = 2 
Query:   71 LNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNV-IQNYQRFIFPDISICFTNPIY---YPPK-DSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLA-------EYL-FMTKTDFY------GHHAWGSIVSCSYMGHDCSYKHFETRHIY-------PFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQ-IDLRITSKQHLNV----NNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTIL---VPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            L  +  F   +T HG  ++      + R++W+  C  A   F+  +  L+++Y   PI T   +++ Q+  FP ++IC  N +     PPK  ++  +++    +       N    F +  +L+       E L  +T  D Y       H     ++SC++ G +C      T   Y        FG C+ FNS K    +  K++ +S   S  P     +   +++ +N   +  + +T   G+ V I D+   PF G   I     Q   +++T  Q   +    N  C+ S E  +  +LF   +  +S     C Y  +    ++ C C   + P +    +P   R  L+ T     + DCL K +    +    +     C    F+  +S +++PA +               E  +  YF    LR + L  I +S+      +  + ++ +    + + ++++            V+ET+ Y    LLSD+GG +G+W+G S
Sbjct:   12 LEQINQFLQETTAHGFGRLGATAGSKWRLYWVMFCLAAYCVFVWQLVGLVNQYNSKPIKTRTQLKHAQKLDFPVVTICNMNVLRASRLPPKLRTKFDQIINNTNKTSPRNSSNSRNAFVDPQDLSFEETKKFEILHAVTAHDDYRELVSAAHQLEDILLSCNFNGVNCRNSKDPTIPTYWTQTWNDNFGNCYMFNSVKT--HNGEKVDLYS---SSVPGESNGLTLQLNLEQN---EYLEGITEVAGMKVTISDQGVLPFPGQQGIRIMPGQSTGIQMTKLQTRRIDPFKNRSCESSNEM-SDKNLFFGYNMTYSIMA--CKYSCLNARKIERCGCTNYNTPEMQKRNIPLCNR--LNST-----IIDCLNKAYDTFEDGSCDRECPPSCSEVSFDLTVSSARWPARS--------------FEVTKYAYF----LRVRVLNKIASSSSKYFVNSENIAQVHVY---YGELDYLL------------VQETLAYTFMSLLSDIGGQMGMWIGIS 474
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Match: EDO30892 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZH3])

HSP 1 Score: 61.6178 bits (148), Expect = 2.650e-10
Identity = 61/266 (22.93%), Postives = 103/266 (38.72%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNY-QRFIFPDISIC--------------------------------FTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVT----IPGGILVMIHDEHTFPFI 775
            F   ++ HG+  +     IR RV W+ +   A  GF   +Y  +  Y E P +T +   + +   FP ++IC                                FT  +  P  ++   KLL + ++N  +Y++       N VN +   F    D      W  +  C + G DC  K+F +     FG+CHTFNS K     ++       ++S+ P   + +          NV   D V+    +P G  V++HD   +P +
Sbjct:    9 FLGNTSLHGVRYLTENSFIR-RVIWLLVVLAAFCGFGYQLYKSITFYYEWPTVTAMTTEWDEELDFPAVTICNLNTLSKENFVKARKRYKSDATTEQLEKEVETFTFFMSAPLNENAKSKLLNDFFENSTFYRER-----GNFVNKSLNDFSHSIDGILSIKW--LRPCQFSGEDCDRKNFSSFVDLNFGLCHTFNSGKKEENALK-------VESLGPNNGLRL--------RLNVQQEDHVSNFYWLPAGFKVLVHDRKEYPIM 251
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Match: EDO39877 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8S3])

HSP 1 Score: 56.6102 bits (135), Expect = 1.967e-8
Identity = 44/185 (23.78%), Postives = 79/185 (42.70%), Query Frame = 2 
Query:   38 SNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKY-LETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTK--TDFYGHHAWGSIVSCSYMGHDCSYKHFETRHI-YPFGVCHTFNS 580
            S+ +  I  +   ++ +F   +T HG   +  +  + +RV W  + G   + F I +     K      IL   ++     ++P ++IC  N +          ++     Q YL    ++    S RVN     F T+     YGH+    +  C++M   CS+K F  R+  Y  G+C+TFN+
Sbjct:   18 SDSEKEIEEQRKTLIKNFSSYTTLHGFHFLLDSSPMPRRVLWTALVGFGLVVFFIQLVMSYGKLRARESILAKGVERPMNVLYPAVTICNQNMM-------RKSRITGTAAQRYLDQLDHIKASLS-RVNRTNERFETEEMVRLYGHNITDMLWECNFMNKPCSHKDFAMRYTSYSRGLCYTFNA 194
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Match: EDO37654 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF66])

HSP 1 Score: 51.2174 bits (121), Expect = 3.913e-7
Identity = 23/77 (29.87%), Postives = 42/77 (54.55%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNV-IQNYQRFIFPDISICFTNPI 316
            F   +T HG +++  ++   QR FW+  C GA + F + ++ L  K+   P+ T + +++     FP ++IC  NPI
Sbjct:   15 FLGYTTAHGFARLVESKNPVQRAFWVLACLGAFVAFGLQVHKLFSKFNRKPVDTYITVKHEMNLEFPAVTICNLNPI 91
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Match: EDO34532 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP23])

HSP 1 Score: 50.447 bits (119), Expect = 1.192e-6
Identity = 24/84 (28.57%), Postives = 44/84 (52.38%), Query Frame = 2 
Query:   62 GRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQR-FIFPDISICFTN 310
            G FL+++  F   +T HG+ ++  A  + +R  W+  C       +     LL +YLE P+++ V  +Y+   +FP ++IC  N
Sbjct:   57 GGFLSLIRDFAASTTAHGIGKVFAADSMVRRALWLLGCLTVYAVMIFMCAQLLVRYLEKPVVSRVEVSYEESLVFPAVTICNLN 140
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Medaka
Match: asic4a (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:101159336])

HSP 1 Score: 71.2478 bits (173), Expect = 1.515e-12
Identity = 107/505 (21.19%), Postives = 192/505 (38.02%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQIARARK--IRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQ-RFIFPDISICFTN----------PIYY-------PPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQ---ITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI-----GNSYILDAY-SQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTI--LVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            F +  + HG++ I  + +  IRQ ++ +      +L FL +       YLE P +T + +      +FP ++IC  N           IY+       PPK+ + HK       + +Y   +M   F NR               GH     ++SC++ G +CS + F   +   +G C+TFN  K   +  ++    +G++ +    Q   + +++             ++ ++  GI V IH +   P+I     G S     + S  + R+T       N R    ++F  Y       + + SA    C  +     V++ C+C   H P    + PPS   C+D   +       L+K   +      P      C+               +T  G  +S +KI +                         S R    K  K        ED++  NF++L +   +   + +E+   Y ++ LL D+GG +GL++GAS
Sbjct:   44 FANSCSLHGINHIFVSGRLGIRQTLWALAFLTSLAL-FLYHAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDADIYHLANLTGLPPKNRDGHKPT-----DLMYPAPDMQDIF-NRT--------------GHQLEEMLMSCNFSGQNCSAEDFSVVYTR-YGKCYTFNGNKTASRKTKQGGMGNGLEIMLDIQQDEYLPIWRET-----------NETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSKEKFPGY------DTYSISA----CRLLCETNEVLRVCKCRMVHMPGTADICPPSKISCVDKALAQ------LQKNSGDTCPCETP------CN---------------LTRYGKELSMVKIPS-----------------------KGSARYLSRKYDK-------SEDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGAS 448
[Close]
BLAST of Acid-sensing ion channel 1C vs. Ensembl Medaka
Match: ENSORLT00000031246.1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:101155423])

HSP 1 Score: 50.447 bits (119), Expect = 4.972e-6
Identity = 68/262 (25.95%), Postives = 106/262 (40.46%), Query Frame = 2 
Query:   89 FCHRSTFHGLSQI-ARARKIRQRVFWITICGGASLGFLINIYYLLDK---YLETPILTNVIQNYQRFI-FPDISICFTNPIYYP--PKDSEAHK-----------------LLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFE---TRHIYPFGVCHTFNSTK------IMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI 775
            F  RST HG+S +    R   +R  WI      S+G L+ +   +D+   Y E P +T + +     I FP I+ C  N   +    ++   H                  L+ EN    L  + + + +     N+ E+      D  GH     ++SCSY G +CS ++F+   TR    +G C+TFNS K      + MK     N    M  ++    + V+     GE       D+ +   GI V IH +   PFI
Sbjct:   21 FATRSTLHGISHMFTYERMCLKRTLWILFFM-LSVGVLVMV--CVDRVQFYFEYPHVTKLDEVAASMIVFPAITFCNLNSFRFSRVTRNDLYHAGELLALLNGRYEIRDPHLVEENVLQVLRERADFESYKPRSFNMREFY-----DRTGHDIKDMLLSCSYRGTECSAENFKVIFTR----YGKCYTFNSGKDGQPLMVTMKGGTG-NGLELMLDIQQDEYLPVW-----GET------DETSFEAGIKVQIHTQEEPPFI 258
[Close]
BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Match: SMESG000024270.1 (SMESG000024270.1)

HSP 1 Score: 1167.91 bits (3020), Expect = 0.000e+0
Identity = 574/578 (99.31%), Postives = 577/578 (99.83%), Query Frame = 2 
Query:   26 MIESSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASXXXXXXXXXXXXXXXXVTVQLKKLRMREKNLIKQQSNSTQLSVSAKESDVYSNTHIFDKILNKNKEDSTVTECKTNINRVLQN 1759
            MIESSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLM+NYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCL+KTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTH SWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDE+FVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASLITIFEFLDLIFDFFDVTVQLKKLRMREKNLIKQQSNSTQLSVSAKESDVYSNTHIFDKILNKNKEDSTVTECKTNINRVLQN
Sbjct:    1 MIESSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMDNYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLRKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHASWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEEFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASLITIFEFLDLIFDFFDVTVQLKKLRMREKNLIKQQSNSTQLSVSAKESDVYSNTHIFDKILNKNKEDSTVTECKTNINRVLQN 578
[Close]
BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Match: SMESG000028094.1 (SMESG000028094.1)

HSP 1 Score: 472.626 bits (1215), Expect = 2.039e-160
Identity = 221/492 (44.92%), Postives = 325/492 (66.06%), Query Frame = 2 
Query:   35 SSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            + N K +I  R L+I L FC +ST HGL+ +A ++ + QR+FW++IC  AS+G  IN+YYL++K++E P+LTN++Q++  F +PDIS CF NPIY+PP ++     LME YQ Y +Y    + FF   +   E+LFM K   Y H AW +++SC+Y+G  CS+ +F  R+++PFG C+TFNST +   D +    F    +     +I ++KAVD+      DPF+ V +P G+L MIHD+ T+P +  SY+LD YSQIDL+I +K HLN+ NRC+  +  ++Y D+F   +T+   K  DCV+  +Q  V + C+C W     +    +  +CLDG  S+    +C+ K +  +    L +CY D C+H  +E+VISQSKFPA+ ER T   WLKILADLE+ E+++FG+S+L  ++LK  N   ++ L++A   +   LLDE+FV+RNFMM++V+P S F+DKVEET EYPISRLLSD+GGCVGLW+GAS
Sbjct:   13 TRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQ----FRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTN-KYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGAS 499
[Close]
BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Match: SMESG000047581.1 (SMESG000047581.1)

HSP 1 Score: 447.203 bits (1149), Expect = 1.859e-149
Identity = 210/499 (42.08%), Postives = 318/499 (63.73%), Query Frame = 2 
Query:   53 VIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNR---------VNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPK-CYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTR---MTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
             I+ R   ++LHF  RST HGL+ +A+AR  + R+FW+TI   ASLGF +N++YL++K+L+TP+LTNV  ++  F +PD+SIC  NPIY+PP+++     L+   + Y  Y+     F  ++         + L++YLFM     Y H +W +I+ C Y+   C+Y HFETRHI+P+G C TFN TK+ ++  R +   + +   +P F++ +YKA++   N  +DPF+D+  P G+LVMIH+ +T+P IG S+++D+++Q+DL+IT+K HL+   +C+  +  YTY D   N S  F  +  DC++  IQ N+   C C     P +       +C D  F   +L  CL  +  ++  E L + CY+DLC+H  F +V+S SK+PAV ER TH+ WL+ L DLE  E++++GQSEL   A+   N+S +    ++ + +   RIDLL+E F+++NFM LR VP+S FMD VEET EYP+SRLLSD+GGCVGLWVGAS
Sbjct:   48 AIFRRLGTVLLHFSRRSTIHGLNHLAQARSAKHRLFWLTISCSASLGFCVNLFYLIEKFLQTPVLTNVFHDFNNFTYPDLSICIVNPIYFPPENTRYRNELISTIEEY--YRLTNSSFHDSKSSYNANLQKIELSDYLFMHSKLEYSHPSWSAIILCRYLKKKCNYTHFETRHIWPYGNCFTFNGTKMGLEGTRDVKKNTVLNGWRPDFKLVIYKALEYPVNLQIDPFNDINKPSGVLVMIHEPNTYPHIGESFVVDSFTQVDLKITTKSHLSSLKKCESIRNNYTYYDFKTNTSNIFVGRQGDCLFSIIQTNIANYCGCQLHKMPILEKHKQLPFCYDKRFRNENLTYCLHASLDDVDREQLRQLCYKDLCEHPSFSTVVSHSKYPAVRERQTHMLWLEHLKDLELLEIEHYGQSELINMAILKSNSSLKHNYKSIREIYDKGRIDLLNEKFINKNFMHLRFVPSSLFMDHVEETEEYPLSRLLSDIGGCVGLWVGAS 544
[Close]
BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Match: SMESG000072895.1 (SMESG000072895.1)

HSP 1 Score: 424.476 bits (1090), Expect = 6.881e-142
Identity = 206/487 (42.30%), Postives = 307/487 (63.04%), Query Frame = 2 
Query:   65 RFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMG-ENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKAL---KMINAS-TRMTLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            +++NI L+FC RST HGL+Q+A  + ++QR FWI IC  AS+G +IN YYL+DK+LE P+LTNV+Q++  F++PD+S CFTNPIY+PP  S     +M  Y+ Y+ +KK    F + ++  A++L+MT+ + Y H  W  +V C Y    CS+     RH++ +G C+TFN ++       K     G + +       +YKAVD+   NF  DPFD++ +P GIL+MIHD +T+P +  SYILD YSQ++L+I +KQHLN+   C+  +  + Y D+F  ++ +   K  DCVY  +Q  V K+CQC WQ    +    +  +C+D          CL   + ++    L  CY D C+H  +E+VISQS FPA+ +R T++ W+K L ++E  E +++G S+L+  AL   K+ NA+ T   ++ A K  R DL+D +FV+RNFMM+++VP SFFMD +EET  YP SRLL D+GG VGLW+GAS
Sbjct:   25 KYINITLNFCQRSTIHGLNQLAFPKSVQQRYFWIFICLSASIGMVINNYYLIDKFLERPVLTNVLQDHTAFVYPDVSFCFTNPIYFPPAKSPYRSFIMAQYKKYIQFKKYPSNFLTVKIKFADFLYMTRNNTYTHPLWSVLVECRYQDLQCSFHDLILRHLFAYGACYTFNYSRFESSAGNKYR--YGNKEL----DFIIYKAVDIPIANFG-DPFDNIMMPSGILLMIHDRNTWPKLQESYILDEYSQVNLKIINKQHLNIGKTCRTVKNKFIYYDVFIKQNISVYGKYSDCVYQNVQEAVAKHCQCQWQEMQVLSHYYNLPFCIDHVVPPRLNFSCLDTAYGDLNNGSLDYCYLDDCEHTTYETVISQSHFPALVDRKTNIQWMKHLVEIETRETEFYGFSDLKFNALKWDKIQNANLTIANISVAFKSGRYDLMDLEFVERNFMMVKIVPTSFFMDMIEETEGYPFSRLLGDIGGSVGLWLGAS 504
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BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Match: SMESG000009914.1 (SMESG000009914.1)

HSP 1 Score: 414.461 bits (1064), Expect = 6.590e-137
Identity = 208/519 (40.08%), Postives = 317/519 (61.08%), Query Frame = 2 
Query:   53 VIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMENYQNY------LYYK-----KNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYC----LDGTFSVNHLKDCLKKTHAEITEEYLPK-CYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKILADLERNEMKYFGQSELRTKALKMINASTRM-----------------TLNKAHKMQRIDLLDEDFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGAS 1510
            +I+ R   I LHF  RST HGL+ +A+AR  ++R+FW+ I   A++GF +N++YL++K+++TPILTN   +Y  FI+PDI+ C  NPI +PPK S  +K L+    NY      L++K     KN D  F  ++ L +YLF+ +   Y H  W +IV C Y+ + CS++HF+   ++P+G C TFN+TK+     R +     +   +P F+I +YK+++   +   DPF+D+T P G+LVMIH+  T+P + +S+I+D+Y+Q+DL+IT+K HL    +C  +++ YTY D    K   F  +  DCV+  IQ  + KNC+C     P ++      +C    L    +V+ ++ CL +T   + ++ +   CYQDLC H  + +VIS SK+PA+ +R TH  WLK L  +E+ E++ +G S L  KA+K  N ST +                 +++  ++  R DL+DE F+D+NFM LR VP+S FMD +EET EYPISRLLSD+GGCVGLWVGAS
Sbjct:   27 IIFKRLGTIFLHFTRRSTIHGLNHLAQARSAKRRLFWLFISTCATVGFFVNLFYLVEKFIQTPILTNTFHDYTSFIYPDITFCLVNPINFPPKTSAQYKYLIGIINNYIRNEESLFHKYINSSKNED--FLPKLELMDYLFIKENISYSHSPWSAIVDCRYLHYPCSWEHFDVHFVWPYGNCFTFNATKMQKNLTRDVQRNMQLNGFRPDFRIIIYKSINRLSSVVHDPFNDITKPSGVLVMIHEIETYPHVSDSFIVDSYTQVDLKITTKSHLESLKKCNPNRQNYTYCDYRSKKCQTFQGRNIDCVFEIIQNKIAKNCKCQMHTMPVLMKNRFYPFCYSLMLSNPLNVSSIRKCLNQTIVGVDKQSIHSICYQDLCSHPSYSTVISHSKYPAIQDRQTHSLWLKKLIVIEKREIENYGISNLFQKAIKR-NHSTLLRNPNFMENQIPIGKRFDSIDAVYRDMRDDLIDELFIDQNFMQLRFVPSSLFMDHIEETEEYPISRLLSDIGGCVGLWVGAS 542
The following BLAST results are available for this feature:
BLAST of Acid-sensing ion channel 1C vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SCNN1B1.337e-720.69sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B1.425e-720.69sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B1.639e-720.69sodium channel epithelial 1 beta subunit [Source:H... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
flr-19.618e-622.99FLR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGI5][more]
flr-19.618e-622.99FLR-1 [Source:UniProtKB/TrEMBL;Acc:G5EGI5][more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
asic4b5.998e-825.40acid-sensing (proton-gated) ion channel family mem... [more]
asic1a7.784e-725.69acid-sensing (proton-gated) ion channel 1a [Source... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ASIC14.130e-624.90acid sensing ion channel subunit 1 [Source:NCBI ge... [more]
ASIC14.368e-623.82acid sensing ion channel subunit 1 [Source:NCBI ge... [more]
ASIC16.398e-624.90acid sensing ion channel subunit 1 [Source:NCBI ge... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Asic51.346e-723.48acid-sensing (proton-gated) ion channel family mem... [more]
Asic53.182e-723.46acid-sensing (proton-gated) ion channel family mem... [more]
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BLAST of Acid-sensing ion channel 1C vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O97742|SCNNB_RABIT3.843e-821.35Amiloride-sensitive sodium channel subunit beta OS... [more]
sp|Q95165|SCNNB_CANLF1.111e-720.45Amiloride-sensitive sodium channel subunit beta OS... [more]
sp|Q708S3|ASI4B_DANRE4.528e-725.40Acid-sensing ion channel 4-B OS=Danio rerio OX=795... [more]
sp|P51168|SCNNB_HUMAN7.871e-720.69Amiloride-sensitive sodium channel subunit beta OS... [more]
sp|Q9R0Y1|ASIC5_MOUSE9.415e-723.48Acid-sensing ion channel 5 OS=Mus musculus OX=1009... [more]
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BLAST of Acid-sensing ion channel 1C vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3SIE11.380e-12939.75Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A564Z6I11.729e-12939.75Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A183SCX11.081e-12741.30Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A448WRB31.199e-12338.73Uncharacterized protein (Fragment) OS=Protopolysto... [more]
A0A3P7LUS41.224e-12139.67Uncharacterized protein OS=Dibothriocephalus latus... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
SCNN1B8.636e-820.86sodium channel epithelial 1 beta subunit [Source:H... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO421379.490e-1521.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308922.650e-1022.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO398771.967e-823.78Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO376543.913e-729.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO345321.192e-628.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Acid-sensing ion channel 1C vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
asic4a1.515e-1221.19acid sensing ion channel subunit family member 4 [... [more]
ENSORLT00000031246.14.972e-625.95acid sensing ion channel subunit 1 [Source:NCBI ge... [more]
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BLAST of Acid-sensing ion channel 1C vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000024270.10.000e+099.31SMESG000024270.1[more]
SMESG000028094.12.039e-16044.92SMESG000028094.1[more]
SMESG000047581.11.859e-14942.08SMESG000047581.1[more]
SMESG000072895.16.881e-14242.30SMESG000072895.1[more]
SMESG000009914.16.590e-13740.08SMESG000009914.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001910 ID=SMED30001910|Name=Acid-sensing ion channel 1C|organism=Schmidtea mediterranea sexual|type=transcript|length=1848bp
TGTTCCGTCTAATATTTTCCTATAAATGATAGAGTCTTCAAATCATAAGT
CGGTAATTTGGGGAAGATTTTTAAATATCGTACTTCATTTTTGTCACAGA
AGTACATTTCATGGCTTGAGTCAAATCGCTCGAGCTCGAAAGATTAGGCA
ACGGGTATTCTGGATAACAATATGTGGTGGAGCTTCTCTTGGGTTTCTAA
TAAATATTTATTATTTATTAGATAAATATCTCGAAACGCCTATTCTTACG
AATGTTATTCAAAATTATCAAAGATTTATTTTCCCAGATATATCAATTTG
TTTTACCAATCCAATTTATTATCCTCCTAAGGATTCAGAAGCTCATAAGC
TTCTCATGGAAAATTATCAAAATTATCTCTACTATAAGAAAAACATGGAT
CCTTTTTTCTCTAATCGAGTTAATCTCGCTGAATATCTTTTCATGACCAA
AACCGACTTCTATGGTCACCATGCATGGGGTTCGATTGTCTCCTGTTCAT
ATATGGGTCACGATTGTTCGTATAAACATTTTGAGACTCGTCATATTTAT
CCGTTTGGCGTTTGTCATACTTTTAATTCCACAAAAATTATGATGAAAGA
CATAAGGAAAATTAACTCGTTTTCTGGAATGCAAAGTGTCAAACCGTTTT
TTCAGATAACAGTATACAAGGCAGTGGATATGGGAGAAAATTTTAACGTG
GATCCGTTTGATGATGTAACCATTCCTGGAGGAATATTAGTAATGATTCA
TGATGAGCACACTTTTCCCTTTATAGGTAACAGTTATATTCTTGATGCTT
ACAGTCAAATAGATCTTCGAATAACCTCAAAACAGCATCTTAATGTTAAT
AATCGTTGCAAAATCAGCCAGGAATTTTATACTTATATGGATTTGTTCGA
AAATAAAAGTACCGCCTTTTCAGCTAAAACCGAAGACTGTGTTTACATAA
CCATTCAAATAAATGTCATGAAAAACTGCCAATGTATATGGCAACACTTT
CCCACTATTTTAGTGCCACCCTCTACTAGATATTGCTTAGATGGCACATT
CTCTGTCAATCACTTAAAGGATTGTCTGAAAAAAACTCACGCTGAAATCA
CTGAGGAATACCTGCCAAAATGTTATCAAGACTTGTGCGACCACAAAGTG
TTCGAATCAGTTATATCACAAAGCAAATTTCCAGCCGTCACCGAGCGAGG
TACACATGTGTCCTGGCTAAAGATTTTGGCCGATCTTGAAAGAAATGAAA
TGAAATATTTTGGTCAATCAGAATTGAGAACAAAAGCTCTAAAAATGATC
AACGCTTCTACAAGAATGACCTTGAATAAAGCGCATAAAATGCAACGAAT
TGATTTGCTGGATGAAGATTTCGTCGATCGTAATTTTATGATGCTTCGGG
TTGTACCTAATTCTTTCTTCATGGATAAAGTCGAAGAGACTATGGAATAT
CCAATAAGTCGTCTTTTGAGTGATGTTGGAGGCTGTGTTGGACTCTGGGT
TGGAGCCAGTTTGATTACGATCTTTGAATTTCTGGATTTGATTTTTGATT
TTTTCGATGTCACTGTACAATTGAAAAAGTTGCGCATGAGGGAAAAAAAC
TTGATAAAACAACAGTCCAATTCCACTCAATTGTCTGTGTCGGCCAAAGA
ATCAGATGTCTATTCTAATACACATATTTTCGATAAAATTCTGAATAAAA
ATAAAGAAGACTCAACTGTGACAGAGTGCAAAACGAATATTAATAGAGTT
TTACAAAATTGATTTATTTTTTTCGGGAGTAGTTTTACTTTTGTTCATGG
TCTCTCATGAGCGCTACCGTTAAATATAATCTTTTTTTAACAAATCAC
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protein sequence of SMED30001910-orf-1

>SMED30001910-orf-1 ID=SMED30001910-orf-1|Name=SMED30001910-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=579bp
MIESSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITIC
GGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYP
PKDSEAHKLLMENYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHA
WGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFS
GMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFI
GNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSA
KTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDC
LKKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHVSWLKI
LADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEDFV
DRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASLITIF
EFLDLIFDFFDVTVQLKKLRMREKNLIKQQSNSTQLSVSAKESDVYSNTH
IFDKILNKNKEDSTVTECKTNINRVLQN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0035725sodium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 168..184
score: 36.24
coord: 311..328
score: 27.11
coord: 154..165
score: 37.33
coord: 367..387
score: 21.52
coord: 82..98
score: 33.65
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 22..505
e-value: 1.4E-55
score: 189.0
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 22..528
NoneNo IPR availableTMHMMTMhelixcoord: 43..65