Fascin domain protein
Overview
Neoblast Clusters
Zeng et. al., 2018
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppEmbryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001907 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Fascin domain protein vs. Ensembl Human
Match: CFAP100 (cilia and flagella associated protein 100 [Source:HGNC Symbol;Acc:HGNC:26842]) HSP 1 Score: 58.151 bits (139), Expect = 4.486e-8 Identity = 57/245 (23.27%), Postives = 119/245 (48.57%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKR---EAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L++V ELE NLSLI+N QE E+ +++ +++ + M+ +++ + + ++ I ED T +LE ++F + K D++++ L+ ++ +Y T++ML +E +D L L+ + + +A++ ++ +R +L+ ++ Q+ H +Q+A A A + + GR ++ RS P H ++ + + + ++E FFF Sbjct: 383 YFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEED-------------TAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEH---LQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT 611
BLAST of Fascin domain protein vs. Ensembl Human
Match: CFAP100 (cilia and flagella associated protein 100 [Source:HGNC Symbol;Acc:HGNC:26842]) HSP 1 Score: 58.151 bits (139), Expect = 4.529e-8 Identity = 57/245 (23.27%), Postives = 119/245 (48.57%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKR---EAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L++V ELE NLSLI+N QE E+ +++ +++ + M+ +++ + + ++ I ED T +LE ++F + K D++++ L+ ++ +Y T++ML +E +D L L+ + + +A++ ++ +R +L+ ++ Q+ H +Q+A A A + + GR ++ RS P H ++ + + + ++E FFF Sbjct: 384 YFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEED-------------TAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEH---LQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT 612
BLAST of Fascin domain protein vs. Ensembl Zebrafish
Match: cfap100 (cilia and flagella associated protein 100 [Source:ZFIN;Acc:ZDB-GENE-060929-352]) HSP 1 Score: 55.0694 bits (131), Expect = 2.134e-7 Identity = 65/253 (25.69%), Postives = 116/253 (45.85%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDM-------NHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSN--TIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLR-QKQHCQDAHQLKIQ-KAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF +PQ+L+N+++ELE NLSLI+N +E EE ++ +Q E I K+M QI + + I ER + LE +F + + D+ D L ++ +YH V T++N T++ML +E + L + + + A++ ++ +R RLR +K + Q Q + Q KA+ + + + +K++ RS+P L K + R +E +FF+ Sbjct: 321 YFKDPQELLNLMTELEEQNLSLIQNTRETEEALEEFRQNAEVIHKNMETESKQLKAQIDIMTETIQRERERTAELELKAKHF--------SFGQCKPEDQ------------DKTFDTLSRKVEEVYHCC---VGETEANLSTLQMLMAIEEKLGELLENAEKIPKDQMSTAERAKEKERR--MRLRDEKAYLQRKQQEERQKKALERSRLDVKKPSVKKLMPRSQPPVRKLHSNKNNETTDRENEEFLYFFS 548
BLAST of Fascin domain protein vs. Ensembl Zebrafish
Match: cfap100 (cilia and flagella associated protein 100 [Source:ZFIN;Acc:ZDB-GENE-060929-352]) HSP 1 Score: 53.5286 bits (127), Expect = 7.397e-7 Identity = 65/253 (25.69%), Postives = 115/253 (45.45%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDM-------NHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSN--TIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLR-QKQHCQDAHQLKIQ-KAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF +PQ+L+N+++ELE NLSLI+N +E EE ++ +Q E I K+M QI + + I ER + LE +F + + D+ D L ++ +YH V T++N T++ML +E + L + + + A++ ++ +R RLR +K + Q Q + Q KA+ + + + +K++ RS+P L K + R +E FF+ Sbjct: 321 YFKDPQELLNLMTELEEQNLSLIQNTRETEEALEEFRQNAEVIHKNMETESKQLKAQIDIMTETIQRERERTAELELKAKHF--------SFGQCKPEDQ------------DKTFDTLSRKVEEVYHCC---VGETEANLSTLQMLMAIEEKLGELLENAEKIPKDQMSTAERAKEKERR--MRLRDEKAYLQRKQQEERQKKALERSRLDVKKPSVKKLMPRSQPPVRKLHSNKNNETTDRENEEILHFFS 548
BLAST of Fascin domain protein vs. Ensembl Xenopus
Match: ENSXETT00000019754.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:4:122532363:122540467:-1 gene:ENSXETG00000007169.1 transcript:ENSXETT00000019754.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.3958 bits (163), Expect = 3.329e-11 Identity = 71/248 (28.63%), Postives = 127/248 (51.21%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLY--VELQSHDR-SVVLKAKKLVDERK---REAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YFN+PQ L+++ SELE NLSLI+N QE EE +++KQ I + M + + + I+HL+ SI +E LE + + + + D ++++ L E++ +Y + + + + N ++ML +E ++ L +E+ R + KAK+ ER+ RE +QKQH ++ +++KA+ A P+ GRK++ RS+P LR+ K I + ++E FF+ Sbjct: 227 YFNDPQQLLDIFSELEEQNLSLIQNSQETEESLEEIKQNIAITQDKMEKETRQL-------KDHIDHLKASIVKEEERAAELELKSRVFAFGQYKSEDQ------EKMLAALGEKVEEVYRACIGE-NRSNYNVLQMLMAIEHQLEELLDNIEMIPQKRLEIAEKAKE--KERRLRLREEKIKQQKQHQEE----RLRKALERAQADPKKTTGRKLMSRSDPPAPKLRIDKDQDKIDKEKEEALLFFS 454
BLAST of Fascin domain protein vs. Ensembl Mouse
Match: Cfap100 (cilia and flagella associated protein 100 [Source:MGI Symbol;Acc:MGI:2141635]) HSP 1 Score: 57.7658 bits (138), Expect = 4.100e-8 Identity = 60/247 (24.29%), Postives = 116/247 (46.96%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISA---ERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKI--DSGIIRNQQEQAFFFN 2038 YF EPQ L++V ++LE NLSLI+N QE EE D++ ++N + M+ +++ + + I++ SK + F E D + D +++ L+ ++ +Y T++ML +E +D L L+ + + +A+K + +R R + + + ++Q+A A A + + GRK+I RS P V++V ++ + I ++++E FFF Sbjct: 385 YFTEPQQLLDVFTKLEEENLSLIQNTQEMEETLDELNVTLKNTQIRMDKEVNLLKQWIASMMISISKEEESAAELELKARVFHFGEYQGDQQ----------------DTMLESLNHKVLEVYRKCVGMQQEANLGTVQMLTVVERQLDELLENLERVPQVKIEQAEKAKERERRMRLREEKAMMQKQLQEERLQRARARAQAKIKKKRGRKLISRSHP--PVIKVKEVREQTLINKDKEEMLFFFT 613
BLAST of Fascin domain protein vs. Ensembl Mouse
Match: Cfap100 (cilia and flagella associated protein 100 [Source:MGI Symbol;Acc:MGI:2141635]) HSP 1 Score: 57.3806 bits (137), Expect = 4.645e-8 Identity = 60/247 (24.29%), Postives = 116/247 (46.96%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISA---ERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKI--DSGIIRNQQEQAFFFN 2038 YF EPQ L++V ++LE NLSLI+N QE EE D++ ++N + M+ +++ + + I++ SK + F E D + D +++ L+ ++ +Y T++ML +E +D L L+ + + +A+K + +R R + + + ++Q+A A A + + GRK+I RS P V++V ++ + I ++++E FFF Sbjct: 231 YFTEPQQLLDVFTKLEEENLSLIQNTQEMEETLDELNVTLKNTQIRMDKEVNLLKQWIASMMISISKEEESAAELELKARVFHFGEYQGDQQ----------------DTMLESLNHKVLEVYRKCVGMQQEANLGTVQMLTVVERQLDELLENLERVPQVKIEQAEKAKERERRMRLREEKAMMQKQLQEERLQRARARAQAKIKKKRGRKLISRSHP--PVIKVKEVREQTLINKDKEEMLFFFT 459
BLAST of Fascin domain protein vs. UniProt/SwissProt
Match: sp|Q4R8V8|CP100_MACFA (Cilia- and flagella-associated protein 100 OS=Macaca fascicularis OX=9541 GN=CFAP100 PE=2 SV=2) HSP 1 Score: 63.929 bits (154), Expect = 3.601e-9 Identity = 58/241 (24.07%), Postives = 120/241 (49.79%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFF 2035 YF EPQ L++V ELE NLSLI+N QE EE +++ + +++ + M+ +++ + + +S I ED T +LE ++F + K D++++ L+ ++ +Y + T++ML +E +D L L+ + + +A++ ++ +R R + Q + + ++Q+A A A + + GR ++ RS+P H ++ + + + ++E FFF Sbjct: 380 YFTEPQQLLDVFRELEEQNLSLIQNRQEMEETLEELSRTLKHTQIRMDREVNQLKQWVSTMMMSITKEED-------------TAAELELKARVFHFGEYKGDQQDKLLESLNWKVLDVYRNCIGTQQEANLGTVQMLTIIEHQLDELLENLERVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEERLQRARARAQAEIKKKRGRTLVCRSQPPVHRIKQESEHTLMDKEKEELLFFF 607
BLAST of Fascin domain protein vs. UniProt/SwissProt
Match: sp|A8I4E9|CP100_CHLRE (Cilia- and flagella-associated protein 100 OS=Chlamydomonas reinhardtii OX=3055 GN=FAP100 PE=1 SV=1) HSP 1 Score: 60.8474 bits (146), Expect = 3.082e-8 Identity = 56/225 (24.89%), Postives = 102/225 (45.33%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMN-------HQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDY--LHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEP 1960 YF EP L+ V +LE +NL I+N QE EE ++++Q++ + K M+ Q+ST+ I A R K L+D T E F + P ++ L +++ +Y D++ S T++ML N+E+ ++ + V A+K ++ +R+ AR + H+ ++ +A+ A P + G+ ++FRS P Sbjct: 331 YFQEPGQLLAVYKQLEESNLFYIQNAQETEEALEELRQKLRDTKTRMDAEAQGLQGQVSTLQASIVAAREKAKRLKDR------TLENEGAFTLSMGSSNAPTSSVTGSSGPGGPVNLKELGDKVREVYVRCGFDADASIS-TLQMLTNIEMKLEEYLNLAEGMTPDYVDGAEKAREKDRRKVARDEKLSTQHREHEARMARALERAAAPVFKKTGKPLMFRSAP 548
BLAST of Fascin domain protein vs. UniProt/SwissProt
Match: sp|Q494V2|CP100_HUMAN (Cilia- and flagella-associated protein 100 OS=Homo sapiens OX=9606 GN=CFAP100 PE=1 SV=1) HSP 1 Score: 58.151 bits (139), Expect = 2.154e-7 Identity = 57/245 (23.27%), Postives = 119/245 (48.57%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKR---EAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L++V ELE NLSLI+N QE E+ +++ +++ + M+ +++ + + ++ I ED T +LE ++F + K D++++ L+ ++ +Y T++ML +E +D L L+ + + +A++ ++ +R +L+ ++ Q+ H +Q+A A A + + GR ++ RS P H ++ + + + ++E FFF Sbjct: 383 YFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEED-------------TAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEH---LQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT 611
BLAST of Fascin domain protein vs. UniProt/SwissProt
Match: sp|Q80VN0|CP100_MOUSE (Cilia- and flagella-associated protein 100 OS=Mus musculus OX=10090 GN=Cfap100 PE=2 SV=2) HSP 1 Score: 57.7658 bits (138), Expect = 2.868e-7 Identity = 60/247 (24.29%), Postives = 116/247 (46.96%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISA---ERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKI--DSGIIRNQQEQAFFFN 2038 YF EPQ L++V ++LE NLSLI+N QE EE D++ ++N + M+ +++ + + I++ SK + F E D + D +++ L+ ++ +Y T++ML +E +D L L+ + + +A+K + +R R + + + ++Q+A A A + + GRK+I RS P V++V ++ + I ++++E FFF Sbjct: 385 YFTEPQQLLDVFTKLEEENLSLIQNTQEMEETLDELNVTLKNTQIRMDKEVNLLKQWIASMMISISKEEESAAELELKARVFHFGEYQGDQQ----------------DTMLESLNHKVLEVYRKCVGMQQEANLGTVQMLTVVERQLDELLENLERVPQVKIEQAEKAKERERRMRLREEKAMMQKQLQEERLQRARARAQAKIKKKRGRKLISRSHP--PVIKVKEVREQTLINKDKEEMLFFFT 613
BLAST of Fascin domain protein vs. TrEMBL
Match: A0A3P7NT10 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS19270 PE=4 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 1.642e-36 Identity = 88/240 (36.67%), Postives = 140/240 (58.33%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERY------------------------XXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEP 1960 +F PQDLV++L+ELE+NNL+LIENVQEQEE C++++ + ++K +N + +T++ IS E+ +I++L+ + I E ++ + FN LERY K + T E+++ LH+QI +Y+ VF + +T+ MLK LE+ ID L L + R+ V+KAKK+VDE R AR RQKQ AH+ ++++A+ A PPR+ GR+++ RS P Sbjct: 86 FFKSPQDLVDILAELESNNLTLIENVQEQEEACERVRVKAARLQKILNMERNTVDAHISREKEEIDNLKRDVTDIVEAKDAINEFNLLERYEKIFHLGGIDQFEMPWMREERSNRKGGPNDKEEPKPTVGEMLEILHDQIHKVYNKVFASESGARLDTLMMLKVLEVTIDDLSRTLSGYSRARVIKAKKIVDEHNRFLARQRQKQQEALAHEARLRRAVEKAREPPRWHRGRRIVERSCP 325
BLAST of Fascin domain protein vs. TrEMBL
Match: A0A0X3NQ98 (DUF4200 domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS9109 PE=4 SV=1) HSP 1 Score: 147.132 bits (370), Expect = 5.394e-33 Identity = 87/240 (36.25%), Postives = 139/240 (57.92%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXX------------------------XXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEP 1960 +F PQDLV++L+ELE+NNL+LIENVQEQEE C++++ + ++K +N + +T++ IS E+ +I++L+ + I ++ + FN LERY+K + T E+++ LH+QI +Y VF + +T+ MLK LE+ ID L L + R+ V+KAKK+VDE R AR RQKQ AH+ ++++A+ A PPR+ GR+++ RS P Sbjct: 459 FFKSPQDLVDILAELESNNLTLIENVQEQEEACERVRVKAARLQKILNVERNTVDAHISREKEEIDNLKRDVGEIVVAKDAINEFNLLERYEKIFHLGGIDQFEMPWMREERNNRKNNATDKEEPKPTVGEMLEILHDQIHKVYTKVFSSEGGARLDTLMMLKVLEVTIDDLSRTLSGYSRARVIKAKKIVDEHNRFLARQRQKQQEALAHEARLRRAVEKAREPPRWHRGRRIVERSCP 698 HSP 2 Score: 89.7373 bits (221), Expect = 9.375e-15 Identity = 44/97 (45.36%), Postives = 68/97 (70.10%), Query Frame = 2 Query: 488 FIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECV 778 FI +++KIC+++LAI KE + L+ ++K E +F+ +E K L ++ H++YLK I Q T++AI LAE E KR I E++KR +Y +AHLNAEC+ Sbjct: 258 FIDDRKKICMMELAIRTKEGEINRLNQMLKAESEFLSREEKDLLLRHDEHDRYLKSICQRTAEAIHLAETEAHKRLVISERIKRTRYKLAHLNAECI 354
BLAST of Fascin domain protein vs. TrEMBL
Match: A0A0R3W6X6 (DUF4200 domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS5984 PE=4 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 1.724e-32 Identity = 89/238 (37.39%), Postives = 135/238 (56.72%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTP--------------------DEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFK 1966 +F PQDLV++L+ELE+NNL+LIENVQEQEE C++++ + ++K ++ + +T+++ I+ E I L I I+ + E ++ F LERY + P +++D LHEQI LY +F +T+ +T+ MLK LE D L L + R VLKAKK VDE R AR RQK+ AH+ K+++A+A + PPR+ GR++I RS+P K Sbjct: 423 FFRSPQDLVDILAELESNNLTLIENVQEQEEACERLRLKAARLQKVLDVERATVDEHIAQEEEIIAMLMSEISEIENSREQIKEFMLLERYDGFSLGSIDQFDPPWLRESRTRRALDEEVEKPTVGQLLDILHEQIHKLYCKIFGSDGTTRLDTLMMLKILETATDDLARSLSKYSRMQVLKAKKTVDEHNRLLARQRQKEVEALAHEAKLKRAIAKSKEPPRWHRGRRIIDRSQPPK 660 HSP 2 Score: 88.5817 bits (218), Expect = 2.035e-14 Identity = 43/97 (44.33%), Postives = 67/97 (69.07%), Query Frame = 2 Query: 488 FIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECV 778 FI ++RKIC+++LAI KE + L +++DE F+ E K L ++ H++YLK I T++AIK A+ ET KR +I +K+KR +Y +AH+NAEC+ Sbjct: 258 FIEDRRKICMINLAIRTKEGEIARLSKMLEDEAAFLANEEKELIIRHDEHDKYLKAICLRTAEAIKKADSETRKRVQITDKIKRTRYKLAHMNAECI 354
BLAST of Fascin domain protein vs. TrEMBL
Match: A0A068WM90 (Coiled coil domain containing protein 37 OS=Echinococcus granulosus OX=6210 GN=EgrG_000164100 PE=4 SV=1) HSP 1 Score: 145.206 bits (365), Expect = 1.755e-32 Identity = 90/238 (37.82%), Postives = 134/238 (56.30%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTP--------------------DEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFK 1966 +F PQDLV++L+ELE+NNL+LIENVQEQEE C++++ + ++K ++ + +T++ I+ E I L I I+ + E ++ F LERY + P +++D LHEQI LY +F ST+ +T+ MLK LE D L L + R VLKAKK VDE R AR RQK+ AH+ K+++A+A + PPR+ GR++I RS+P K Sbjct: 426 FFRSPQDLVDILAELESNNLTLIENVQEQEEACERLRLKAARLQKVLDVERTTVDDHIAREEDIIAKLMKEISEIENSREQIKEFTLLERYDVFSLGSIDQFDPPWLRESRTRRALDEEAEKPTVGQLLDILHEQIHKLYCRIFGTDGSTRLDTLMMLKILESATDDLARSLAKYSRMQVLKAKKTVDEHNRLLARQRQKEVEALAHEAKLRRAIAKSKEPPRWHMGRRIIDRSQPPK 663 HSP 2 Score: 88.5817 bits (218), Expect = 1.907e-14 Identity = 47/111 (42.34%), Postives = 73/111 (65.77%), Query Frame = 2 Query: 458 PREPFLSNTD----FIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECV 778 P E + N D FI ++RKIC+++LAI KE + L+ +++DE F+ E K L ++ H++YLK I T++AIK A+ ET KR +I +K+KR +Y +AH+NAEC+ Sbjct: 247 PLEAYDKNFDQVNTFIDDRRKICMVNLAIRTKEGEIARLNKMLEDEAAFLANEEKELIIRHDEHDKYLKAICLRTAEAIKKADSETRKRVQITDKIKRTRYKLAHMNAECI 357
BLAST of Fascin domain protein vs. TrEMBL
Match: A0A0R3WK56 (DUF4200 domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS1087 PE=4 SV=1) HSP 1 Score: 142.895 bits (359), Expect = 1.105e-31 Identity = 87/236 (36.86%), Postives = 134/236 (56.78%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTP--------------------DEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEP 1960 +F PQDLV++L+ELE+NNL+LIENVQEQEE C++++ + ++K ++ + +T+++ I+ E I L I ++ + E ++ F LERY + P +++D LHEQI LY +F +T+ +T+ MLK LE D L L + R VLKAKK VDE R AR RQK+ AH+ K+++A+A + PPR+ GR++I RS+P Sbjct: 426 FFRSPQDLVDILAELESNNLTLIENVQEQEEACERLRLKAAKLQKVLDAERTTVDEHIAREEEIIAALMREISDVEVSREQIKEFTLLERYDAFSLGSIDQFDPPWLRESRTRRAMDEDVEKPTVSQLLDILHEQIHRLYCRIFGTDGNTRLDTLMMLKILESATDDLARSLGKYSRMQVLKAKKTVDEHNRLLARQRQKEVEALAHEAKLKRAIAKSKEPPRWHRGRRIIDRSQP 661 HSP 2 Score: 88.5817 bits (218), Expect = 2.117e-14 Identity = 46/114 (40.35%), Postives = 71/114 (62.28%), Query Frame = 2 Query: 455 TPREP------FLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECV 778 PR P F FI +RK+C+++LAI KE + L+ +++DE F+ E K L ++ H++YLK I T++AIK A+ ET KR +I +K+KR +Y +AH+NAEC+ Sbjct: 244 APRSPEAYDENFDQVNAFIDGRRKVCMINLAIRTKEGEIARLNKMLEDEAAFLANEEKELIIRHDEHDKYLKAICLRTAEAIKKADSETRKRVQITDKIKRTRYKLAHMNAECI 357
BLAST of Fascin domain protein vs. Ensembl Cavefish
Match: cfap100 (cilia and flagella associated protein 100 [Source:NCBI gene;Acc:103023090]) HSP 1 Score: 51.2174 bits (121), Expect = 3.063e-6 Identity = 68/253 (26.88%), Postives = 117/253 (46.25%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNH-------QISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLY--VELQSHDR-SVVLKAKKLVDERKREAARLR-QKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L+++LSELE NLSLI+N QE EE + + +E +K+M H QI + + I E+ + LE + FN + T D+ ++ L ++ +Y S + + S T++ML +E + L VE+ DR ++ KAK+ + ++ QKQ ++ +++KAM A + G+K++ RS P L+ + D + ++E +FF Sbjct: 313 YFTEPQQLLDLLSELEEQNLSLIQNAQETEEGLVEFRNTVEQTRKNMEHEALQLKQQIDIMTETIQKEKERTAELELKVRL----------FN-----------FGNENTDEDDTLNALSRKVEAVYRSCIGSTEDSLS-TLQMLTTIEGRLGELLEKVEMIPADRLAIAEKAKERERRLRLRDEKIYLQKQQQEE----RMKKAMERAQAQIKRTSGKKLMPRSLPPVRKLKDDQHDDVTDKEKEEHLYFFT 539
BLAST of Fascin domain protein vs. Ensembl Cavefish
Match: cfap100 (cilia and flagella associated protein 100 [Source:NCBI gene;Acc:103023090]) HSP 1 Score: 51.2174 bits (121), Expect = 3.134e-6 Identity = 68/253 (26.88%), Postives = 117/253 (46.25%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNH-------QISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLY--VELQSHDR-SVVLKAKKLVDERKREAARLR-QKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L+++LSELE NLSLI+N QE EE + + +E +K+M H QI + + I E+ + LE + FN + T D+ ++ L ++ +Y S + + S T++ML +E + L VE+ DR ++ KAK+ + ++ QKQ ++ +++KAM A + G+K++ RS P L+ + D + ++E +FF Sbjct: 280 YFTEPQQLLDLLSELEEQNLSLIQNAQETEEGLVEFRNTVEQTRKNMEHEALQLKQQIDIMTETIQKEKERTAELELKVRL----------FN-----------FGNENTDEDDTLNALSRKVEAVYRSCIGSTEDSLS-TLQMLTTIEGRLGELLEKVEMIPADRLAIAEKAKERERRLRLRDEKIYLQKQQQEE----RMKKAMERAQAQIKRTSGKKLMPRSLPPVRKLKDDQHDDVTDKEKEEHLYFFT 506
BLAST of Fascin domain protein vs. Ensembl Cavefish
Match: cfap100 (cilia and flagella associated protein 100 [Source:NCBI gene;Acc:103023090]) HSP 1 Score: 51.2174 bits (121), Expect = 3.303e-6 Identity = 68/253 (26.88%), Postives = 117/253 (46.25%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNH-------QISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLY--VELQSHDR-SVVLKAKKLVDERKREAARLR-QKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFN 2038 YF EPQ L+++LSELE NLSLI+N QE EE + + +E +K+M H QI + + I E+ + LE + FN + T D+ ++ L ++ +Y S + + S T++ML +E + L VE+ DR ++ KAK+ + ++ QKQ ++ +++KAM A + G+K++ RS P L+ + D + ++E +FF Sbjct: 337 YFTEPQQLLDLLSELEEQNLSLIQNAQETEEGLVEFRNTVEQTRKNMEHEALQLKQQIDIMTETIQKEKERTAELELKVRL----------FN-----------FGNENTDEDDTLNALSRKVEAVYRSCIGSTEDSLS-TLQMLTTIEGRLGELLEKVEMIPADRLAIAEKAKERERRLRLRDEKIYLQKQQQEE----RMKKAMERAQAQIKRTSGKKLMPRSLPPVRKLKDDQHDDVTDKEKEEHLYFFT 563
BLAST of Fascin domain protein vs. Ensembl Nematostella
Match: EDO43894 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX27]) HSP 1 Score: 79.7221 bits (195), Expect = 1.474e-15 Identity = 67/248 (27.02%), Postives = 132/248 (53.23%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLY--VELQSHDR-SVVLKAKKLVDERKREAARLRQKQHCQDAHQL----KIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFF 2035 +F +PQ L+++ +ELE NLSLI+N QE EE ++MKQ I+ + MNH+ + + +I+ L D+I +E LE + + Y + D ++++ L++++ +Y + ++ S T++ML N+E ++ L+ +E+ +R + KAK E++R RLRQ++ + +L ++++A+ A P+ + G+ ++FRSEP + + D + ++E +FF Sbjct: 358 FFGDPQQLLDIFAELEEQNLSLIQNSQETEEALEEMKQTIKQTQDRMNHETEIL-------KGQIDFLNDAIKREQERAAELEMKSKMFSYGEFKAEDQ------EKMLAALNKKVEEVYRNCIGDNEANIS-TLQMLTNIENRLEELFEQIEIMPPERVEMAEKAK----EKER---RLRQREEKMEQQRLHQEDRVRRALERAQAEPKRKTGKPLMFRSEPPQTRKKQQDADKKQDKEEEELKYFF 584
BLAST of Fascin domain protein vs. Ensembl Medaka
Match: ENSORLT00000011808.2 (cilia and flagella associated protein 100 [Source:NCBI gene;Acc:101158036]) HSP 1 Score: 50.0618 bits (118), Expect = 6.403e-6 Identity = 54/254 (21.26%), Postives = 117/254 (46.06%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNH-------QISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSN--TIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQE---QAFFFN 2038 YF +PQ L+++++EL NLSLI++ EE ++++ IE +++++ QI + + + ER++ L+ + + + + ER D ++D L E+++ ++ S VD +N T E + N+E + SL L+S + +K+ + KR R + + ++ + ++++ + + + + GRK++ R P ++V ++ RN E Q + F Sbjct: 234 YFTDPQQLLDLMAELTEQNLSLIQDSVRVEEKLEELQHSIEATRREIDEDERQIKVQIDEVKQRMDRERARAAKLQQKV-------QLHTSLSTEER---------------DAMLDALSEKVAKVHRSC---VDDRMTNLSTFEKVANIENCMLSLLEGLESIPGETLESMRKIKESEKRTRQREEKLREQKEKQEERMKRYLERSFSDSKKKSGRKLMPRCMPVPQKVKVKTVE----RNPAEDEIQEYLFG 458
BLAST of Fascin domain protein vs. Ensembl Medaka
Match: ENSORLT00000038744.1 (cilia and flagella associated protein 100 [Source:NCBI gene;Acc:101158036]) HSP 1 Score: 49.6766 bits (117), Expect = 8.885e-6 Identity = 54/254 (21.26%), Postives = 117/254 (46.06%), Query Frame = 2 Query: 1313 YFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNH-------QISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSN--TIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQE---QAFFFN 2038 YF +PQ L+++++EL NLSLI++ EE ++++ IE +++++ QI + + + ER++ L+ + + + + ER D ++D L E+++ ++ S VD +N T E + N+E + SL L+S + +K+ + KR R + + ++ + ++++ + + + + GRK++ R P ++V ++ RN E Q + F Sbjct: 321 YFTDPQQLLDLMAELTEQNLSLIQDSVRVEEKLEELQHSIEATRREIDEDERQIKVQIDEVKQRMDRERARAAKLQQKV-------QLHTSLSTEER---------------DAMLDALSEKVAKVHRSC---VDDRMTNLSTFEKVANIENCMLSLLEGLESIPGETLESMRKIKESEKRTRQREEKLREQKEKQEERMKRYLERSFSDSKKKSGRKLMPRCMPVPQKVKVKTVE----RNPAEDEIQEYLFG 545
BLAST of Fascin domain protein vs. Planmine SMEST
Match: SMESG000023075.1 (SMESG000023075.1) HSP 1 Score: 1201.81 bits (3108), Expect = 0.000e+0 Identity = 665/665 (100.00%), Postives = 665/665 (100.00%), Query Frame = 2 Query: 47 MLKERKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTVKVKKLPTPREPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVXXXXXXXXXXXXXXXXWNCHRQRERKEAMERTSLMNELKIDAILNEVEMDLRTXXXXXXXXXXXIRYHGRRYAAENKNNSTENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNXXXXXXXXXXXXXXXXXXXXXXXXXXYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFNL 2041 MLKERKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTVKVKKLPTPREPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVKLEEEYLKLKTYKEFLWNCHRQRERKEAMERTSLMNELKIDAILNEVEMDLRTESDDSFFDESDIRYHGRRYAAENKNNSTENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNEQNFETEFIKEEERELDENDLNSNDLYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYKKLFFLDDLKLTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFNL Sbjct: 1 MLKERKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTVKVKKLPTPREPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVKLEEEYLKLKTYKEFLWNCHRQRERKEAMERTSLMNELKIDAILNEVEMDLRTESDDSFFDESDIRYHGRRYAAENKNNSTENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNEQNFETEFIKEEERELDENDLNSNDLYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYKKLFFLDDLKLTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFFNL 665
BLAST of Fascin domain protein vs. Planmine SMEST
Match: SMESG000023182.1 (SMESG000023182.1) HSP 1 Score: 522.702 bits (1345), Expect = 5.037e-178 Identity = 325/661 (49.17%), Postives = 450/661 (68.08%), Query Frame = 2 Query: 59 RKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTVKVKKLPTPREPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVXXXXXXXXXXXXXXXXWNCHRQRERKEAMERTSLMNELKIDAIL-NEVEMDLRTXXXXXXXXXXXIR-YHGRRYAAENKNNSTENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNXXXXXXXXXXXXXXXXXXXXXXXXXXYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFF 2035 + S + K FP+ F+KII PII+TKKVEKRIGP PP++PNYLK + E+NPF K RI ELK ES R+ +E ++Y +P+ E+V R R FNA+Y+LKK+ + EI E L +E F SN FIV+KR++CLLDLAI+IKE Q +LD+I+ EE IK+EN+ LQ E HNQ +K I Q TSDAIKLAEK+T K+N+++EKVKRA+YNMAHLNA+CVKLEEEYL+LKTYKEFL CH QRE+K +ERTS M+ELKID ++ + DL++ + + ++R ++ R + N N++ +FNQN N ++ + + +L+K+KSLIL GF+ N + +S++ ++I + E ++ E+ DENDLN +L+ PQDLV++LS LE+NNLSLIENVQEQEEMC+ ++ +I IK+DM Q IN + E +K+ L D+I CI E + F+ F++LE+Y+K+F +L+ TT D+++DYLHE+IS LYHSVFEKVDSTKSNT+EML+ +E LI+SLY+ELQS+DRS + K+K+LVDERKREAAR+RQ+Q ++A LKI+KAM A MPPRY++GRKV++RS P K + V +ID +R ++E FFF Sbjct: 6 KASQTIKIKNDFPSPCKFEKIIYPIIHTKKVEKRIGPPPPMVPNYLKVMNCEDNPFTITKKKRIDELKKLESERRNFEKNIYETYPMQENVGRSIRNKFNASYELKKVIYTQDMVEIMEVLNSPETSKPITKHLKEKFQSNIHFIVDKRRVCLLDLAINIKEAQLQKLDEIIIQEEKTIKEENEELQNQLEIHNQNMKSICQKTSDAIKLAEKQTAKKNEVIEKVKRARYNMAHLNADCVKLEEEYLRLKTYKEFLRQCHVQREKKHILERTSFMDELKIDVLIKTALSDDLQSFNSQDSKSDIELRVFNKMRNSISNTNSNFGTGKEFNQN--------NNSLPEKTQ------------NRLDKIKSLILSGFA--NVNNYSDVEELIVPEYSSFQQFESVESIEKVFDENDLNETNLFLESPQDLVDLLSHLESNNLSLIENVQEQEEMCEHLRGKIRKIKQDMESQNFIINGHVKKEETKLGDLLDNIACIDEIDRFILNFDELEKYRKIFNFGNLEFTTIDQMIDYLHEKISNLYHSVFEKVDSTKSNTVEMLRRIESLINSLYIELQSYDRSTIQKSKRLVDERKREAARIRQRQLSKEAEALKIEKAMIKARMPPRYKFGRKVVYRSNPPKPICHVKEIDWDAVREEEEHLFFF 644
BLAST of Fascin domain protein vs. Planmine SMEST
Match: SMESG000070000.1 (SMESG000070000.1) HSP 1 Score: 309.686 bits (792), Expect = 1.256e-95 Identity = 241/668 (36.08%), Postives = 380/668 (56.89%), Query Frame = 2 Query: 53 KERKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKE--IGEELEERTVKVKKLPTPREPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVXXXXXXXXXXXXXXXXWNCHRQRERKEAMERTSLMNELKIDAILNEVEMDLR-TXXXXXXXXXXXIRYHGRRYAAENKNNS----TENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNAD-EFSEITDIIAITNXXXXXXXXXXXXXXXXXXXXXXXXXXYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFF 2032 K R TS +PT F+K+ P I + +I P +P +LKE+ + NPF +I + +LK E RK +E + D P+ EHV RD R +NA +LK+L++ I KE I +E + PR F+ DFIV++RKICLL+L I IKE++ +L+ IV++EE IKKE + L+ ++ LK+ + TS +KL + E KRN +K+K A++ LNA C+ LE EY + K +KEFL NC+RQ E + R S ++E K++A+L E+E + + FD ++ +EN +N+ +N+N F +NS V ER ++++ N + L+ LKS I++G S N + E + T + + + ++ + + +YF++P +L+NV+SELE NNL LIENVQEQEE+C+ + ++ IK + I+ I LI++ R +N++ + I I+ L ++ RYK++F+L+DLK+TT DE++ YL ++S LY +V +KVD+ + + IEM+ +E L+D L VEL +++ S + KAKK VDE+K AARL+ K+ D +K++K M A PPRYRYGRKV++RSEP K L VA ++ +R+++ FF Sbjct: 6 KRRSVTSAGL--KYPTISRFEKLHLPGIRESSISTKIFIGFPKVPPHLKEIHCKGNPFTEINSLKTHQLKKLEKRRKNFEKK-FHDLPVSEHVTRDIRMKYNAKNKLKQLQYAIALKENSIKNNSDE---SLHSFRLPRMKFIQTFDFIVSRRKICLLELGIKIKEQEMSKLNRIVEEEERLIKKEYESLERDQRKEDESLKVTCERTSKTLKLVDDENEKRNLSAKKLKHAKFKRDKLNAHCIHLESEYSRFKAFKEFLRNCYRQNEYESMTHRRSKLDEYKMEAVLMEMEKQHKFSNESRDSFDVDFLKLPEIVGNSENASNAYFRRIKNKNKFIRNS-------GIKDVYIKERLIKCKTILSN-SDLDTLKSNIILGLSNVNNNIELTSFRSDEEDTTLEFLLSSSFEIMTERSKDSASSGDFVYFSDPLELINVISELEINNLCLIENVQEQEELCESLIKKTHKIKSKIEKHINFIESLINSGREDLNNINEKINFIENINVNLNKHFNINRYKEIFYLEDLKITTLDELIGYLFNKVSKLYSTVIQKVDTNEIDLIEMMTKIESLVDELTVELLTYNDSAISKAKKAVDEKKILAARLKHKEMMLDKEIIKMKKTMEEANKPPRYRYGRKVVYRSEPEKPNLIVAATNTDTLRHEEYNFFF 659
BLAST of Fascin domain protein vs. Planmine SMEST
Match: SMESG000023179.1 (SMESG000023179.1) HSP 1 Score: 290.426 bits (742), Expect = 3.395e-88 Identity = 228/663 (34.39%), Postives = 380/663 (57.32%), Query Frame = 2 Query: 92 FPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTV-KVKKLPTPR---EPFLSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVXXXXXXXXXXXXXXXXWNCHRQRERKEAMERTSLMNELKIDAILNEVEMD-----------LRTXXXXXXXXXXXIRYHGRRYAAENKNNSTENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNXXXXXXXXXXXXXXXXXXXXXXXXXXYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFF 2035 FPT F K ++ ++ KK+ +++GP PI+P YL E NPF IK + L ++ RK ++ FP E+V R+ R +FNAN+ +K+L++ +E E LE + + T R EP S+ DF+V+KR++CLLDLA +K++ LD VK +E+ IK E + L++ +++ LK + NTSDA+K+ ++ + K++KI++K+KRA++ LNAEC+KLE+E+ LK+Y+ FL++C+ ++ + ++ RTS ++++++ ++ E+E + L TE + + + R + N + E F NS LS N+ ++ER + T N Q KS+ LI + + II I ++ F+ E + D+ F +PQDLVNV + LE NNL+LIENVQEQEE+CD + R++ IK +M ++ I+ LI E ++ LE+SI I +TE+F + N LERY+ +F+L+DL LTT DE++ YL +Q+ LY F++ +S N IE+L +E +D LYV++Q + ++ ++ AKK VD+RK +A+RL+QK+ ++ + + + +PP++R+GRK+++RS PF + K + IR +E FFF Sbjct: 18 FPTKSKFDKSVEETLHGKKIIEKVGPIRPIIPKYLSEYNEGGNPFRAIKYENTETLIASDKQRKLFDKEKNLKFPFFENVNRNVRNLFNANFAVKELQYKFDREEFLELLEHPEISRANTTATVRFQYEPRKSDYDFVVDKRRVCLLDLAKRLKQQHISNLDVSVKIQENSIKHELQLLEKEKTENDKLLKSVCVNTSDAVKVLDEASLKKHKIIQKLKRARFIKDKLNAECIKLEDEFNILKSYRWFLYSCYNRQLKSLSLARTSFLSDVQMSTVIKEMEREVKLSIEESEASLNTEIVKALATNENGVIYMRPESLTENNTNNEVFKGFEINSHSNELS-NRRRGSSIEREKMTMDNFSNSVQSSLFKSVKLIPILLNEPN-------IITIDSKDTFKDNETLELDSNDDDI-------LFEDPQDLVNVFNNLEMNNLNLIENVQEQEEICDNLVNRLKKIKFEMAIKVKEIDDLIKRENHNVDGLEESIVFIMKTEDFTRSLNKLERYRSIFYLEDLDLTTVDELLGYLLQQVLDLYFIFFDRGNSIVKNIIEILCRIESYVDKLYVKMQMYSKNQIIMAKKSVDDRKFKASRLKQKELEKEMRLKRFHDVIEKSKLPPKHRFGRKLVYRSPPFDKKMSKEKGNLESIRKLEENQFFF 665
BLAST of Fascin domain protein vs. Planmine SMEST
Match: SMESG000023181.1 (SMESG000023181.1) HSP 1 Score: 281.567 bits (719), Expect = 3.031e-85 Identity = 219/659 (33.23%), Postives = 356/659 (54.02%), Query Frame = 2 Query: 89 GFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLKELPIEENPFLDIKMNRIKELKTAESNRKAYESSLYRDFPIIEHVKRDQRTIFNANYQLKKLKHDITWKEIGEELEERTVKVKKLPTPREPF-----LSNTDFIVNKRKICLLDLAISIKEEQYMELDDIVKDEEDFIKKENKRLQEINEAHNQYLKIIFQNTSDAIKLAEKETFKRNKIVEKVKRAQYNMAHLNAECVXXXXXXXXXXXXXXXXWNCHRQRERKEAMERTSLMNELKIDAILNEVEMDLRTXXXXXXXXXXXIRYHGRRYAAENKNNS-----TENQNDFNQNSIETILSYNQTMVDNMERFEATRSLVFNKTQLEKLKSLILIGFSTSNADEFSEITDIIAITNXXXXXXXXXXXXXXXXXXXXXXXXXXYFNEPQDLVNVLSELEANNLSLIENVQEQEEMCDQMKQRIENIKKDMNHQISTINKLISAERSKINHLEDSIYCIKETEEFLETFNDLERYXXXXXXXXXXXTTPDEVMDYLHEQISVLYHSVFEKVDSTKSNTIEMLKNLEILIDSLYVELQSHDRSVVLKAKKLVDERKREAARLRQKQHCQDAHQLKIQKAMANALMPPRYRYGRKVIFRSEPFKHVLRVAKIDSGIIRNQQEQAFFF 2035 FPT F+ I T+ V++ + P++P YL EL ENPF+ + ELK E RK + R++ + E+V RD R FNA Y LK ++ + E+ E +P+ +P +SN DFI +KR++CLLDLA I ++ +LD+IV+ EE FIKKEN+ LQ+ + + +YLK + Q T ++ A+K+ ++ K+++K+KRA++ + LN EC++LEEE LK K FL +E E S ++E+ + L E+ GR+ +A N++ N+ F +N+ ++ N ++ +F S F+K +LE LKSLIL F ++ E S I ++ ++ +++ + +P DLV +++ LE NLSLIENVQEQEEMCD MK++I +IK +M+ Q I++ I E KI + SI ++E L+ F +ERYK F L K + D++++Y+ +QI+VL S+F+ DS + +EML+ +E L+DSLY++LQ +D+ ++ KK +DE KR+A R R + ++ K++K M + +PPRY GRKV++RS+P + + +++ IR Q+E +FF Sbjct: 16 NFPTLSKFENDILDFTRTRPVDRLSIYEKPVVPGYLSELFCNENPFMATQYRHTNELKDLEKQRKDFNREKIRNYSVTENVNRDTRIKFNAKYSLKNFQYILNRNEMSE-------AKAPIPSALKPVHNLKTVSNYDFIFSKREVCLLDLAGKITQKNIAKLDEIVEKEEKFIKKENQLLQKEKKENEEYLKSVCQRTYKIVRRADKQVLRKEKVIKKLKRAKFVSSKLNTECIQLEEELENLKNLKLFLKKSFHNKEIDEICPNLSFLDEIPLSEQLREL---------------------GRQDSAPEDNSAEGLEEIGNEGFFVKNNYYSV--ENPKSLNFSNKFPQLYS--FSKEKLEDLKSLILSDFGGNSKREVSSTKPIFT------ELSKSFSDDLEFSEDSFSSHQKEMLRDPMDLVAIVTNLEIKNLSLIENVQEQEEMCDLMKKKILDIKMEMDKQTKDIDESIQEENKKIEKIVASIENLQEKCSSLDKFYTIERYKAFFCLKGFKKSHLDDLLEYIVKQINVLDFSIFDNQDSDERGPLEMLRQIESLVDSLYIDLQRYDKKTLILTKKRLDECKRQANRARLNKQIKETRAEKLKKVMESFNLPPRYVGGRKVMYRSQPLQRSVHCEEVNLDDIRQQEEIDYFF 636 The following BLAST results are available for this feature:
BLAST of Fascin domain protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of Fascin domain protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Fascin domain protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Fascin domain protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of Fascin domain protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of Fascin domain protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of Fascin domain protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Fascin domain protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Fascin domain protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 3
BLAST of Fascin domain protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Fascin domain protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Fascin domain protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Fascin domain protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Fascin domain protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001907 ID=SMED30001907|Name=Fascin domain protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2089bpback to top protein sequence of SMED30001907-orf-1 >SMED30001907-orf-1 ID=SMED30001907-orf-1|Name=SMED30001907-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=666bp MLKERKSTSTKFMCGFPTSRGFQKIIDPIINTKKVEKRIGPDPPILPNYLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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