Potassium voltage-gated channel protein

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  386 EYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDID-IDTDKVSKDDLYAK-FGLEEKHQ----SGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLK--NHPLNTIPSFT-VGNRNELL 1672
            E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D I  D    +DL AK  G+E+        G    W +LQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F I       V + +S  + +   +T    +YVE +C +WFT E ++R + +P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P        PA   P  S+P F     N   N+  S T +G  N LL
Sbjct:  101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTS-VVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP--------PA---PQASSPTFCKTELNMACNSTQSDTCLGKDNRLL 533          

Query:  386 EYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDID-IDTDKVSKDDLYAK-FGLEEKHQ----SGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLK--NHPLNTIPSFT-VGNRNELL 1672
            E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D I  D    +DL AK  G+E+        G    W +LQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F I       V + +S  + +   +T    +YVE +C +WFT E ++R + +P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P        PA   P  S+P F     N   N+  S T +G  N LL
Sbjct:  101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTS-VVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP--------PA---PQASSPTFCKTELNMACNSTQSDTCLGKDNRLL 533          

Query:  386 EYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDID-IDTDKVSKDDLYAK-FGLEEKHQ----SGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLK--NHPLNTIPSFT-VGNRNELL 1672
            E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D I  D    +DL AK  G+E+        G    W +LQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F I       V + +S  + +   +T    +YVE +C +WFT E ++R + +P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P        PA   P  S+P F     N   N+  S T +G  N LL
Sbjct:  101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTS-VVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP--------PA---PQASSPTFCKTELNMACNSTQSDTCLGKDNRLL 533          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNL---HNISVSDNSSWA--------ISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESV 1555
            MDSE R+ILN+GG RHETYK TLKKIPATRLS+LT  LANYDPVLNEYFFDRHPGVF+Q+LNYYRTGKLHYP DVCGPL+EEEL++WGLDSN+ EPCCWMT +  R T++ L+ L+++DI+ D+    +LY +FG E+ + +  +  W+K++ +IW +F++P SS S++ +A I+VFF++ +I+ FCLKT    RIP L    N S +  S+ +        I K++ + H  F Y+E ICN+WFTIEI+ R    PS+F +L++PVNIID +A L+FY+D++ S    +        LEFFSIIRIMRLFKLT H +GL IL+HTFRAS KEL+LLVFFL + +V+FA+L+YYAER + N  N F SIP GLWWAIVTMTT+GYGD+ PHTY+G  +G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V
Sbjct:   22 MDSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD------LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 462          

Query:  236 RGANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNL---HNISVSDNSSWA--------ISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESV 1555
            R   MDSE R+ILN+GG RHETYK TLKKIPATRLS+LT  LANYDPVLNEYFFDRHPGVF+Q+LNYYRTGKLHYP DVCGPL+EEEL++WGLDSN+ EPCCWMT +  R T++ L+ L+++DI+ D+    +LY +FG E+ + +  +  W+K++ +IW +F++P SS S++ +A I+VFF++ +I+ FCLKT    RIP L    N S +  S+ +        I K++ + H  F Y+E ICN+WFTIEI+ R    PS+F +L++PVNIID +A L+FY+D++ S    +        LEFFSIIRIMRLFKLT H +GL IL+HTFRAS KEL+LLVFFL + +V+FA+L+YYAER + N  N F SIP GLWWAIVTMTT+GYGD+ PHTY+G  +G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V
Sbjct:   15 RQTVMDSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD------LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 459          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNL---HNISVSDNSSWA--------ISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESV 1555
            MDSE R+ILN+GG RHETYK TLKKIPATRLS+LT  LANYDPVLNEYFFDRHPGVF+Q+LNYYRTGKLHYP DVCGPL+EEEL++WGLDSN+ EPCCWMT +  R T++ L+ L+++DI+ D+    +LY +FG E+ + +  +  W+K++ +IW +F++P SS S++ +A I+VFF++ +I+ FCLKT    RIP L    N S +  S+ +        I K++ + H  F Y+E ICN+WFTIEI+ R    PS+F +L++PVNIID +A L+FY+D++ S    +        LEFFSIIRIMRLFKLT H +GL IL+HTFRAS KEL+LLVFFL + +V+FA+L+YYAER + N  N F SIP GLWWAIVTMTT+GYGD+ PHTY+G  +G++CA+ GVLTI+LPVPVIVSNF+MFYSHTQARSK+PKKRR VL ++ V
Sbjct:    1 MDSEYRIILNVGGVRHETYKHTLKKIPATRLSRLTTNLANYDPVLNEYFFDRHPGVFAQILNYYRTGKLHYPLDVCGPLFEEELKYWGLDSNECEPCCWMTLSGTRDTQDVLKTLDELDIEVDQTEGPELYKRFGWEDDYHNDSLSAWQKIKPRIWRLFDEPNSSRSAQFIAAISVFFLITAIIVFCLKTHPGLRIPELAPFGNFSRNHRSTSSRIHPAQINIDKANSRPHPTFMYIETICNIWFTIEILARFSSCPSRFEYLRAPVNIIDIVATLTFYIDLLSSMFGATAD------LEFFSIIRIMRLFKLTHHNSGLKILMHTFRASAKELMLLVFFLVLGVVVFASLVYYAERVESNEDNQFVSIPIGLWWAIVTMTTIGYGDITPHTYLGRLIGSICALAGVLTIALPVPVIVSNFAMFYSHTQARSKMPKKRRGVLSMDQV 441          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWA----------ISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRP-----KTPAGLTPLLSNPPFS-LKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKAN 1741
            MD+E+RVILN+GG RHETY   LKKIPATRLS+LT  LANYDPVLNEYFFDRHPGVFS +LNYYRTGKLHYPT+VCGPL+EEELEFWGLD+NQVEPCCWMTYT+HR T++TL ++  +D+D D  +++++  KFG E+ + +G++  W++L+ ++WA+F++P+SS  +++++V+ + F++ISI+ FCLKT   FRIP++   +   N S            + K++ + H  F YVE + N+WF+ E + R +  P+   FL++PVN+IDF+A +SFY+D  L          N + +EFFSIIRI+RLFKLT+H  GL IL+ TF+AS +EL LLVFF+ + IVIFAAL+YYAER +HN +N F+SIP GLWWA++T+ T+G+GD+VP T +G  VG++CA+ GVLTI+LPVPVIVSNF+MFYSH QARSKLPKKRRRVL    ++P      T   ++ L    P S   ++P +  P     N   LL +  P G T       PKK   N
Sbjct:   97 MDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISVVNIIFVIISIVCFCLKTHPSFRIPDIDISTTMGNFSAPLNGVQMNNIYVGKTATRAHPSFFYVELLSNIWFSGEFLTRMVFCPNVATFLRTPVNLIDFIATVSFYIDWALDRTLSG---SNRDSVEFFSIIRILRLFKLTQHSTGLKILIQTFKASAQELFLLVFFVLLGIVIFAALVYYAERVEHNEENQFSSIPVGLWWAVITICTIGFGDLVPQTSLGRLVGSVCALMGVLTIALPVPVIVSNFAMFYSHAQARSKLPKKRRRVLQPHEIKPVVGRSTTAVMISALTQRGPVSGGGSNPSDGGPLSAFSNNTPLL-VCPPDGST------KPKKLSQN 600          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNL---HNISVSDNSSW-----AISKSSPQT--HQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRP 1561
            MD+E+RVILN+GG RHETY   LKKIPATRLS+LT  LANYDPVLNEYFFDRHPGVFS +LNYYRTGKLHYPT+VCGPL+EEELEFWGLD+NQVEPCCWMTYT+HR T++TL ++  +D+D D  +++++  KFG E+ + +G++  W++L+ ++WA+F++P+SS  +++++ ++V FI+ S  SF LKT   F+IP++   +++ V D   +      I    P T  H  F YV+ ICN+WFTIE++IRSL  PS   F++SP+ IID ++  +F+ + +L  +    Q  +L  L+F S+I ++RLFKLT+H +GL IL+ TF+AS +EL LLVFF+ + IVIFAAL+YYAER Q N  N F SIP GLWW++VT++TVG+GDMVP TY+GM VG+LCA+ GVLTI+LPVPVIVSNFS  YSH+QAR+KLPKKRRRVL    V+P
Sbjct:    1 MDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLDANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPSFQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTSPHPNFFYVDLICNIWFTIELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILI--QTGSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAKLPKKRRRVLQAHEVKP 446          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLT 1582
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++
Sbjct:    5 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS 455          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLT 1582
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++
Sbjct:    5 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS 455          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLT 1582
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++
Sbjct:   20 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS 470          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYK 1735
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++     P     + P+ +  +      N+   +++P  D  +T+   P+  K
Sbjct:    5 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSG-CGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSDEYTTMIGKPRDGK 505          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLT 1582
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++
Sbjct:    5 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS 455          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKD-------DLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND D+DT+ +          ++  +  + +   +    +W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   ++  DN+S    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +  S   + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGND-DMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTYVNTQDNTSRFHLET--ETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTE---------------ALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAK-FGLEE-KHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHF-----RIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
               D   RVILN+GG RHETY++TLK +P TRL+ L                     Y    NEYFFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L +  ++++DT+   +DD Y K  G+E+     G +  W + Q  IW +F+DPYSS +++ +A  ++FFI++SI +FCL+T   F     +   L N +++D S     +   +T    +YVE +C LWFT E ++R   +P K  F+KS +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +  +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    2 GKFDERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGIDETDVEPCCWMTYRQHRDAEEALDVF-EMNVDTE---EDDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNTIINKTDPLRNETLTDIS----QQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 443          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKD-------DLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND D+DT+ +          ++  +  + +   +    +W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   ++  DN+S    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +  S   + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGND-DMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTYVNTQDNTSRFHLET--ETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKD-------DLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND D+DT+ +          ++  +  + +   +    +W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   ++  DN+S    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +  S   + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPVEMGND-DMDTEALGDPGDGDEELEMTKRLAVGDSPDTKGAGFWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTYVNTQDNTSRFHLET--ETVVYLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSSEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTE---------------ALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAK-FGLEE-KHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHF-----RIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
               D   RVILN+GG RHETY++TLK +P TRL+ L                     Y    NEYFFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L +  ++++DT+   +DD Y K  G+E+     G +  W + Q  IW +F+DPYSS +++ +A  ++FFI++SI +FCL+T   F     +   L N +++D S     +   +T    +YVE +C LWFT E ++R   +P K  F+KS +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +  +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    2 GKFDERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGIDETDVEPCCWMTYRQHRDAEEALDVF-EMNVDTE---EDDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNTIINKTDPLRNETLTDIS----QQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 443          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLT--------------EALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVS-----KDDLYAKFGLEE-KHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 1543
              +D   R+ILN+GG RHETY++TLK +P TRL+ L                   N     NE+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D+ T +       ++DL  +  +E+     G +  W +LQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F    ++     +N +  IS    +T    +YVE +C +WFT E ++R +  P K  F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +  +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P
Sbjct:    2 GKIDENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNTI-INKTETVNNGTELISLIEIETDPALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLT--------------EALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVS-----KDDLYAKFGLEE-KHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 1543
              +D   R+ILN+GG RHETY++TLK +P TRL+ L                   N     NE+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D+ T +       ++DL  +  +E+     G +  W +LQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F    ++     +N +  IS    +T    +YVE +C +WFT E ++R +  P K  F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +  +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P
Sbjct:    2 GKIDENERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNT-IINKTETVNNGTELISLIEIETDPALTYVEGVCVVWFTFEFLVRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKYIP 461          

Query:  239 GANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAER-------FQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNP 1600
            G N DS+ ++++N+GG RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ VLNYYRTGKLH P DVCGPLYEEEL FWG+D   VE CCWM Y +HR  EE L      +   ++   D    +  L+E  +   +  W++LQ K+WA+FEDPYSS +++ +A  ++FFI+ISI +FCL+T   F  + N   +    N +   +    +T    +YVE IC +WFT E +IR +  P K  F+KS +NIIDF+A+L FYL+I LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER          +    F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    +P +P    P L +P
Sbjct:   30 GKNEDSD-KIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGD--LKRLCLQEDGRK--LGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-RPPQPGSPNYCKPDLQSP 489          

Query:  239 GANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAER-------FQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNP 1600
            G N DS+ ++++N+GG RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ VLNYYRTGKLH P DVCGPLYEEEL FWG+D   VE CCWM Y +HR  EE L      +   ++   D    +  L+E  +   +  W++LQ K+WA+FEDPYSS +++ +A  ++FFI+ISI +FCL+T   F  + N   +    N +   +    +T    +YVE IC +WFT E +IR +  P K  F+KS +NIIDF+A+L FYL+I LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER          +    F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    +P +P    P L +P
Sbjct:   30 GKNEDSD-KIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGD--LKRLCLQEDGRK--LGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-RPPQPGSPNYCKPDLQSP 489          

Query:  239 GANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAER-------FQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNP 1600
            G N DS+ ++++N+GG RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP VF+ VLNYYRTGKLH P DVCGPLYEEEL FWG+D   VE CCWM Y +HR  EE L      +   ++   D    +  L+E  +   +  W++LQ K+WA+FEDPYSS +++ +A  ++FFI+ISI +FCL+T   F  + N   +    N +   +    +T    +YVE IC +WFT E +IR +  P K  F+KS +NIIDF+A+L FYL+I LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER          +    F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ + +P    +P +P    P L +P
Sbjct:   30 GKNEDSD-KIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGD--LKRLCLQEDGRK--LGRWKRLQPKVWALFEDPYSSKAARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-RPPQPGSPNYCKPDLQSP 489          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  386 EYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDID-IDTDKVSKDDLYAK-FGLEEKHQ----SGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSP------QTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLK--NHPLNTIPSFT-VGNRNELL 1672
            E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D I  D    +DL AK  G+E+        G    W KLQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F I       V + +   I+ +SP      +T    +YVE +C +WFT E ++R + +P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P        PA   PL S+P F     N   N+  S T +G  N LL
Sbjct:  105 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI-------VKNKTEPVINGTSPVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP--------PA---PLASSPTFCKTELNMACNSTQSDTCLGKENRLL 537          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYD 373
              ++S  RVILN+GG RHETY++TLK +P TRL+ L  +    D
Sbjct:    2 GKIESNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGD 45          

Query:  386 EYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDID-IDTDKVSKDDLYAK-FGLEEKHQ----SGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSP------QTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLK--NHPLNTIPSFT-VGNRNELL 1672
            E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L I    D I  D    +DL AK  G+E+        G    W KLQ ++WA+FEDPYSS +++ +A  ++FFI++SI +FCL+T   F I       V + +   I+ +SP      +T    +YVE +C +WFT E ++R + +P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLP+KR++ +P        PA   PL S+P F     N   N+  S T +G  N LL
Sbjct:  105 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI-------VKNKTEPVINGTSPVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIP--------PA---PLASSPTFCKTELNMACNSTQSDTCLGKENRLL 537          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYD 373
              ++S  RVILN+GG RHETY++TLK +P TRL+ L  +    D
Sbjct:    2 GKIESNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGD 45          

Query:  263 RVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQ---------------------------------WWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQ--------THQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHN-----SKNH--FNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            ++++N+GG RHETY++TL+ +P TRL+ LTE  A    +YDP  +E+FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VE CCWMTY +HR  EE L      D   +  +        GL+++  +G                                    WW + Q ++WA+FEDPYSS +++ VA  ++FFI+ISI +FCL+T   F   ++ N +V+  S   I  + P+        T    +YVE +C +WFT E ++R    P K  FLKS +NIID +A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +       NH  F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   91 KIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFI--HISNKTVTQASP--IPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 552          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR----PKTPAGLT 1582
            NMDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT+HR T+ETL +L+ +D+DT+K S+++L  KFG EE +  G I WW++++ +IW++F++PYSS ++K + V++VFFI ISILSFCLKT    R+P + NI+V   + ++ W + K+    H  F Y+E +CN WFT EI++R + +P+K+ F+KS VNIID++A LSFY+D++L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TYIGM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE  R    P  P G++
Sbjct:    5 NMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVS 455          

Query:  236 RGANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTD---KVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNL--HNISVSDNSSW-AISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVR 1558
            +G +MD   R++LN+GG RHETY+ATLKKIPATRLS+LT +LAN+DP+LNEYFFDRHP VF+ +LNYYRTGKLHYPTDVCGPL+EEEL++WGLD++  EPCCWM     + T+ETL +L+ +D D +   ++ + D   KFG EE +  G    W KL+ ++W++F++PYSS ++K++A I+V FI ISI SFCLKT   FR+P L   NI++       +I + S +   IF  +E +CN+WFT+E+IIR +  PSK  F KSP+N+ID +A LSFY D ++  + E    E  +++EF S+IRI RLFKLT+H  GL IL+HTFRAS KEL+LLVFFL + IVIFAAL+YYAE+ + N  N F SIP GLWWAI TMTTVGYGDM PHT  G  VG+LCA+ GVLTI+LPVPVIVSNF+MFYSH QAR KLPK+RRRVLPVE +R
Sbjct:   31 KGISMD--ERIVLNVGGVRHETYQATLKKIPATRLSRLTPSLANFDPLLNEYFFDRHPAVFAMILNYYRTGKLHYPTDVCGPLFEEELQYWGLDASDTEPCCWMQLLHAKDTQETLAVLDRMDADHEDDPQLREQDTMKKFGWEEDYFQGKRTRWMKLKPQMWSLFDEPYSSQAAKLIAGISVLFIFISIFSFCLKTHQSFRLPVLIGQNITMPGGVVQPSIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVED---EPKDVVEFLSMIRIFRLFKLTQHHQGLQILIHTFRASAKELILLVFFLILGIVIFAALVYYAEKMEANPNNQFQSIPLGLWWAICTMTTVGYGDMTPHTSFGRLVGSLCAVMGVLTIALPVPVIVSNFAMFYSHNQARDKLPKRRRRVLPVEQIR 472          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDT--------------DKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   R+++N+GG RH+TY++TL+ +P TRL+ L E  A    +YDP  +E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L       +D               D   + ++  +  L +        +W + Q +IWA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N   I    N +        +T    +Y+E +C +WFT E ++R +  P+K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER      +       HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 448          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV----SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTP 1585
            D++NRVILN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT HR T+ETL IL+ +D+DTDK++ +DLY KFGLE+K+++ ++  W+K++ K+WA+F++PYSS ++KIVAV++VFFIVISILSFCLKT    R+P + N++V    +D  S+A+ K+  + H  F Y+E +CN WFT EI+ R  V P KF FLKSPVNIIDF+A LSFY+D++L+ +    +  + E+LEFFSIIRIMRLFKLTRHIAGL IL+HTF+AS KEL+LLVFFL VFIV+FAAL+YYAER  +N +N F+SIP GLWWAIVTMTTVGYGDM P TY GM VGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK  AG  P
Sbjct:    3 DADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTTHRETQETLTILDRLDLDTDKLAPEDLYKKFGLEDKYENNELNLWQKVKPKLWALFDEPYSSVAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIITNVTVVVDSNDTMSYALYKTRSEPHSAFFYIECVCNSWFTFEIVTRFSVTPDKFEFLKSPVNIIDFIATLSFYMDLVLNQVLSEAE-ASYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIHYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMFVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKV-AGTGP 449          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVS----DNSS-WAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTP 1570
            D+ENRVILN+GG RHETYKATLKKIPATRLS+LTEALANYDPVLNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELEFWGLD+NQVEPCCWMTYT HR T+ETLQIL+ +D+DTDK +++D+  KFGLEE++ SG++ WW+K++ +IWA+FE+PYSST++KIVA+ ++FFIV+SILSFCLKT  + R+P + N+++S    DN++ W + K     H+ F ++E  CN WFT E++IR +VAP+K  F+++P+NIID +A LSFYLD +L+ +    + EN ++LEFFSIIRIMRLFKLTRH  GL IL+HTF+AS  EL LL+FFL + IVIFA+L++YAER Q+N  N F SIP GLWWAIVTMTTVGYGDMVP TY+GM VGALCA+TGVLTI+LPVPVIVSNFS+FYSHTQAR+KLPKKRRRVLPVE+VRPK P
Sbjct:    3 DAENRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDANQVEPCCWMTYTTHRDTQETLQILDRLDLDTDKPTEEDIMKKFGLEEQYNSGEMNWWQKIKPRIWALFEEPYSSTTAKIVAIGSIFFIVVSILSFCLKTHPNMRVPVIQNVTLSKGNADNTTIWVLEKKGTDAHRAFFFIECACNAWFTFELLIRVVVAPNKLEFMRAPINIIDLVATLSFYLDFLLTRL----KKEN-DILEFFSIIRIMRLFKLTRHSPGLKILIHTFKASAHELSLLIFFLILGIVIFASLIFYAERIQYNPSNDFTSIPVGLWWAIVTMTTVGYGDMVPKTYVGMFVGALCALTGVLTIALPVPVIVSNFSLFYSHTQARAKLPKKRRRVLPVEAVRPKGP 442          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV------SDNS---------------------------SWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKT 1567
            MDSENRVILN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLD+NQVEPCCWMTYT HR T+ETLQILND+D+DT+  ++++LYAKFGL++ +QSG +  W+K + KIW +F++ YSS  +K +AVI+VFFIV+SILSFCLKT+S+ RIP L+N SV      SD                             SW I K + + H IFSY E I N WFT EI +R LV PSK+ F++SPVNIID LAL+SFY+D++L+N+       + + LEFFSIIRIMRLFKLTRHIAGL IL+HTFRAS+KELVLLVFFL VFIVIFAALMYYAERFQ N +N F SIP GLWWAIVTMTTVGYGD VP TY+GM VGA+CAITGV+TISLPVPVIVSNFS FY+HTQA+SKLPKKRRRVLPVE+VRPK+
Sbjct:    1 MDSENRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDANQVEPCCWMTYTSHRETQETLQILNDLDLDTEH-TEEELYAKFGLDDAYQSGQLTLWQKFKPKIWMLFDESYSSLCAKFLAVISVFFIVLSILSFCLKTSSNLRIPQLYNESVLLISTGSDYQTPDEMRTAHELTRLRRSVPPEPVEGELSWTIRKRTVKAHSIFSYFEMISNAWFTFEITVRFLVTPSKYEFIRSPVNIIDLLALISFYVDLLLTNIMSDDA--SYDALEFFSIIRIMRLFKLTRHIAGLKILIHTFRASMKELVLLVFFLMVFIVIFAALMYYAERFQFNPRNDFASIPVGLWWAIVTMTTVGYGDQVPKTYLGMIVGAMCAITGVMTISLPVPVIVSNFSRFYTHTQAQSKLPKKRRRVLPVEAVRPKS 470          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV----SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKT 1567
            D++NRVILN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLDSNQVEPCCWMTYT HR T+ETL IL+ +D+DTDK++++DLY KFG EE+  S ++ +W++++ K+WA+F++PYSS ++KIVAV++VFFIVISILSFCLKT    R+P + N +V    + ++S+ + K   + H  F Y+E +CN WFT EII R  V P K  FLKSPVNIIDF+A LSFY+D++L+ +  S +  + E+LEFFSIIRIMRLFKLTRHIAGL IL+HTF+AS KEL+LLVFFL VFIV+FAAL+YYAER Q+N +N F+SIP GLWWAIVTMTTVGYGDM P TY GM VGALCA+TGVLTI+LPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK+
Sbjct:    3 DADNRVILNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTSHRETQETLGILDRLDLDTDKLAEEDLYKKFGWEEEFLSNELNFWQRIKPKLWALFDEPYSSMAAKIVAVVSVFFIVISILSFCLKTFPGLRVPIISNETVLIDENGSTSFVLHKHRSEPHTAFLYIECVCNSWFTFEIITRFAVTPDKLEFLKSPVNIIDFIATLSFYMDMVLNQVL-SEEETSYEVLEFFSIIRIMRLFKLTRHIAGLKILIHTFKASAKELLLLVFFLIVFIVVFAALIYYAERIQYNPENSFDSIPIGLWWAIVTMTTVGYGDMAPKTYAGMLVGALCALTGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPKS 444          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVS---DNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGN 1657
            MDSENRV+LN+GG RHETYKATLKKIPATRLS+LTEALANYDP+LNEYFFDRHPGVF+QVLNYYRTGKLHYPTDVCGPL+EEELE+WGLDSNQVEPCCWMTYT HR T+ETL +L+ +D+DTDK S+++L  KFG E+ + SG++ WW+KL+ K+W++F++PYSS ++K++ VI+VFFI +SILSFCLKT    R+P + N++V    + ++W + K +   H+ F Y+E +CN WFT EI+IR + +P+KF+FLK+ VN+IDF+A LSFY+DI+L     +  +EN ++LEFFSIIRIMRLFKLTRH +GL IL+ TFRAS KEL LLVFFL + IVIFA+L+YYAER Q N  N FNSIP GLWWA+VTMTTVGYGDM P TY+GM VGALCA+ GVLTI+LPVPVIVSNF+M+YSHTQAR+KLPKKRRRVLPVE VR      + P+   P      + +N  P   +GN
Sbjct:    1 MDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEYWGLDSNQVEPCCWMTYTAHRDTQETLAVLDRLDLDTDKPSEEELARKFGFEDDYFSGNLSWWQKLKPKLWSLFDEPYSSQAAKVIGVISVFFICVSILSFCLKTHPDMRVPVIENVTVQTAENTTAWTLDKKATNAHEAFFYIECVCNTWFTFEILIRLIASPNKFMFLKASVNMIDFIATLSFYVDILLQKF--ASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQANPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYVGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEHVR------VGPIAPQPKRGGGPNDMNRGPGPKMGN 465          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDI------QWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERF-------QHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND           D   +  + ++   GD         W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N  +I   DNS+    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER        + +   HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPAELGNDDTDADGLGDPGDGDEELEMTKRLALGDAPDGKAGGLWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTDIDPVDNSTRIYQET--ETEVFLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSKEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDI------QWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERF-------QHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND           D   +  + ++   GD         W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N  +I   DNS+    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER        + +   HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPAELGNDDTDADGLGDPGDGDEELEMTKRLALGDAPDGKAGGLWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTDIDPVDNSTRIYQET--ETEVFLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSKEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETL--------QILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDI------QWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERF-------QHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D ++RV++N+GG RH+TY++TL+ +P TRL+ L E  A    +YD  ++E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L        ++ ND           D   +  + ++   GD         W++ Q ++WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N  +I   DNS+    ++  +T    +Y+E +C +WFT E ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER        + +   HF +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGPAELGNDDTDADGLGDPGDGDEELEMTKRLALGDAPDGKAGGLWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTDIDPVDNSTRIYQET--ETEVFLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSKEAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQ--------------------WWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQI--FSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D E RV+LN+GG RHETY+ TL+ +P TRL++L E     +   +++FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L          D   + +L  +   +  H++ D                       W++ Q K+WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N     V DN    + ++ PQT  +   +Y+E +C +WFT E +IR    P K  F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +       +F +IP G WWA+VTMTT+GYGDM P T  GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DDEERVVLNVGGVRHETYRGTLRTLPGTRLARLAE---QAEGAGHDFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELSFWGIDETDVEPCCWMTYRQHREAEEALVSFGGA-APLDNGHRHELEVEVAADGTHEAADGDEGAEMTRRLAHGDAADASGGRWKRWQKKMWALFEDPYSSRYARWVAFASLFFILVSITTFCLETHEAFNPIINRTEYDVVDNE--IVERNVPQTETMVQLTYIEGVCVVWFTFEFLIRITFCPDKLKFVRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFILLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTTSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQ--------------------WWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQI--FSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D E RV+LN+GG RHETY+ TL+ +P TRL++L E     +   +++FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L          D   + +L  +   +  H++ D                       W++ Q K+WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F  I N     V DN    + ++ PQT  +   +Y+E +C +WFT E +IR    P K  F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +       +F +IP G WWA+VTMTT+GYGDM P T  GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    5 DDEERVVLNVGGVRHETYRGTLRTLPGTRLARLAE---QAEGAGHDFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELSFWGIDETDVEPCCWMTYRQHREAEEALVSFGGA-APLDNGHRHELEVEVAADGTHEAADGDEGAEMTRRLAHGDAADASGGRWKRWQKKMWALFEDPYSSRYARWVAFASLFFILVSITTFCLETHEAFNPIINRTEYDVVDNE--IVERNVPQTETMVQLTYIEGVCVVWFTFEFLIRITFCPDKLKFVRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFILLIIFLALGVLIFATMIYYAERIGANPNDPRASEHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTTSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 446          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTE--ALAN--YDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDID-TDKVSKD-DLYAKFGLEEKH-QSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQ-------THQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHN-----SKNH--FNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            D   RV++N+GG RHETY+ TL+ +P TRLS LTE  A AN  YD   NE+FFDRHP VF+ +LNYYRTGKLH P++VCGPL+EEEL FWG+D   VEPCCWM Y +HR  EE L    + DI+  D+V++D ++  +FGL+E+    G + +  + Q ++WA+FEDPYSS +++IVA+ ++ FI+ISI +FCL+T   F      N  ++   ++ I+  + Q       T  +  YVE +C  WF+ E ++R +  P K +F+K+ +N+IDF+A+L FYL++ LS++      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA +++YAERF  N     + +H  F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NFSM+YS   A
Sbjct:   33 DENERVVINVGGTRHETYRGTLRTLPGTRLSWLTEPDAFANFDYDAKGNEFFFDRHPTVFAHILNYYRTGKLHCPSEVCGPLFEEELIFWGIDETDVEPCCWMNYRQHRDAEEALVSFENPDINGNDEVNEDGEVSKRFGLDERSPDGGKLGFLRRWQPRMWALFEDPYSSRAARIVALASLLFILISITTFCLETHEAF------NTVLNKTENYTINNVTTQKVYVDVETDPVLMYVEGVCVAWFSFEFLVRIICCPDKKVFIKNYLNVIDFVAILPFYLEVGLSSLTSKPARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIFYAERFGANPNDPTASDHTSFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFSMYYSLAMA 465          

Query:  263 RVILNIGGFRHETYKATLKKIPATRLSKL---------TEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWES-GQMENLE-MLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKR 1528
            RV LN+GG  HE    TL+++P TRL +L         +E   +Y    NEYFFDRHPG F+ VLN+YRTG+LH   ++C   + +EL++WG+D   +E CC   Y  H+  E+  + L   + ++ +  + D +      +K +            K+W + E+P SS ++K +A++++ FIV+S ++  L T     +P+L +    D  S  I   +P+  Q    VE +C  WFT+E ++R + AP+K+ F K  +N+ID +A+L +Y+ I L+       Q +N+  +++ F I+RI+R+ KL RH  GL  L  T R S  EL LL+ FL + I+IF++L+++AE+ + ++K  F+SIP   WWA +TMTTVGYGD+ P T +G  +G LC I GVL I+LP+P+IV+NFS FY   + + K  K+R
Sbjct:    1 RVRLNVGGLVHEVLWRTLERLPRTRLGRLHATNTHGALSELCDDYSIADNEYFFDRHPGAFASVLNFYRTGRLHMSEEMCALSFGQELDYWGVDEIYLETCCQARY--HQKKEQMSEELRR-EAESAREREGDEFEGTCCADKRR------------KLWELLENPNSSLAAKGMAIVSILFIVLSTIALSLNT-----LPDLQH---KDEFSHIID--NPKLAQ----VEAVCIAWFTMEYLLRFMSAPNKWKFFKGALNVIDLMAILPYYITIFLTESSRGVSQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEPDTK--FHSIPASFWWATITMTTVGYGDIYPMTLLGKIIGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAVKRR 402          

Query:  245 NMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTG-KLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYS 1492
             +  +NRV++N+ G R ET   TL + P + L    +    +DP+ NEYFFDR    F  +L YY++G +L  P DV   ++ EE+EF+ L    V           +  E TL        DT              EE++  G     +  Q  +W +FE    S ++K++++++    ++SI   CL+T   FR  N     V  N +    ++S      F  +E  C +WF  E+ +R    PSK  F+K  +N ID LA++ +++ ++L  M +  Q     +L+   ++R++R+FKL+RH   L IL  T +ASL+EL +L FFL V +VIF+  +YY E    + + HF+SIP   WWA+VTMT VGYGDM P T  G  VGALCAITGVLTISLPVPVIVSNF  FY+
Sbjct:    4 QLTCDNRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVA----------KYGENTL--------DTP-------------EEENVHG-----KDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDN----QVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQ-PLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVE--ADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYN 377          

Query:  800 SFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQ-----HNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLP 1543
            +FCL+T   F   N    +V   S      +  +T     Y+E +C +WFTIE ++R L +P+K  F+K+ +NIID +A+L FYL++ LSN+   G  E L  L     +RI+R+FKLTRH  GL +L HT +AS  E +LL+ FL + ++IFA ++YYAER          K HF SIP G WWA+VTMTT+GYGDM P T+ GM VGALCA++GVLTI++PVPVIV+NF M+YS   A+ KLPKK+   +P
Sbjct:   20 TFCLETHEAFT--NASGTTVVPLSPMPTESTEYETAPALMYIEGMCVVWFTIEFMVRILTSPNKREFMKNKLNIIDLIAILPFYLEVGLSNLKSKGAREVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLKASTNEFLLLIIFLALGVLIFATMIYYAERLGAKPGIDEDKTHFTSIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALSGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNSYMP 270          

Query:  260 NRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTG-KLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYS 1492
             RV++N+ G R ET   TL + P + L    +    +DP+ NEYFFDR    F  +L YY++G +L  P DV   ++ EE+EF+ L    V           +  E TL        DT              EE++  G     +  Q  +W +FE    S ++K++++++    ++SI   CL+T   FR  N     V  N +    ++S      F  +E  C +WF  E+ +R    PSK  F+K  +N ID LA++ +++ ++L  M +  Q     +L+   ++R++R+FKL+RH   L IL  T +ASL+EL +L FFL V +VIF+  +YY E    + + HF+SIP   WWA+VTMT VGYGDM P T  G  VGALCAITGVLTISLPVPVIVSNF  FY+
Sbjct:    1 QRVVINVSGERFETQLKTLDQFPDSLLGHPDKRARYFDPLQNEYFFDRSHVNFDAILFYYQSGGRLCKPVDVPSDVFREEVEFYELGEEAVA----------KYGENTL--------DTP-------------EEENVHG-----KDFQQHVWRLFESRDGSIAAKMLSLMSFVTTILSITVMCLETLPQFRKDN----QVHANRTEFSIRTSIYNLDPFFMLETACVVWFIFELAVRFYACPSKTSFMKDFMNAIDILAIMPYFITVVLEIMQQQDQTRQ-PLLKIIRLVRVLRIFKLSRHCQDLQILGLTLKASLRELAMLSFFLFVAVVIFSGAIYYVE--ADDPQKHFSSIPDAFWWAVVTMTLVGYGDMWPMTVGGKIVGALCAITGVLTISLPVPVIVSNFKYFYN 369          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTE---ALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSY--VEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRR 1531
            ++ +RV++N+GG +HETY  TLK IP TRL  +TE    L  +DP  +E+FFDRHPGVF+QVLN+YRTGKLH P DVCGPL+E+EL FWG+D  QVEPCCW+ Y +HR  +  L   +  D D + V   D+     + +  +  +  WW+K Q +IW +FE+PYSS  ++++A IT+F I+ S+  FCL+T   F           DN         P+T + F    +E +C  WFT+E + R +  P K  F K P+N ID  A+L FYL +I+         + + +L    +IR+ R+FKL+RH  GL IL HT R+S  EL LLVFFL + +VIF+++++YAE+       HF +IP   WWA+VTMTT+GYGDMVP T+ G  VG+LCA+ GVL I+LPVPVIVSNFS++YSH +AR KLP+++R
Sbjct:   13 NAGDRVVINVGGQKHETYIGTLKNIPDTRLYWITENGTQLPEFDPNTSEFFFDRHPGVFAQVLNFYRTGKLHCPNDVCGPLFEDELAFWGIDELQVEPCCWLNYKQHREAQANLDPFDHHDSDNESVGDMDMSVYGLVADSIRQRNRTWWKKYQPRIWTMFEEPYSSIPAQVLAFITMFLIISSVCLFCLETVPKF-----------DN---------PKTSEGFVLYILEAVCVAWFTLEFLFRLIFCPDKLSFFKKPMNWIDLGAILPFYLTLIV----RESNFKTIVVLRVVRLIRVFRIFKLSRHSYGLQILGHTLRSSCSELFLLVFFLTIGVVIFSSVIFYAEK--DTKGTHFTTIPHTFWWAVVTMTTLGYGDMVPITWQGQIVGSLCAVCGVLMIALPVPVIVSNFSLYYSHAKARMKLPRRKR 418          

Query:  260 NRVILNIGGFRHETYKATLKKIPATRLSKLTEA---LANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKD--DLYAKFGLEEKHQSG-DIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1534
            +RV +N+GG RHETYK+TLK IP TRLS + EA    A++DP   EYFFDRHPGVF+ VLNYYRTGKLH P DVCGPL+E+EL FWG+D  QVE CCW+TY +HR  +ETL     ++ + +    +  DL  ++G     +S  D  WWE+ Q +IW + E+P+SST +K++A  T+  I++S+  FCL++   F    L ++ V                     +E IC +WFT+E+++R +  P+K  F K  +N IDFLA++ FY+ +  +N        +++ L    +IRI R+FKL+RH +GL IL HT RAS +EL+LL+FFL + +V+FA+L++Y E+    +K  F  IP   WWA+VTMTTVGYGDM P +  G  +G+LCA+ GVLTI+LPVPVIV+NFS++YSH QAR KLPKKRRR
Sbjct:    1 DRVSINVGGVRHETYKSTLKNIPDTRLSWIAEASAGAADFDPSTGEYFFDRHPGVFANVLNYYRTGKLHCPLDVCGPLFEDELGFWGIDDQQVESCCWLTYRQHRDAQETLAAFEGVEFENEYEDDEEPDL-GRYGFNFAAESEPDKTWWERYQPRIWTLMEEPHSSTLAKVIAYTTLTLILVSVGIFCLESMEKFSEKYLKDLLV--------------------ILEGICVVWFTLELMVRFVFCPAKCEFFKKIMNWIDFLAIVPFYVSLGFNN-----NNNDIDALMIIRLIRIFRIFKLSRHSSGLQILGHTLRASFRELLLLIFFLLIGVVLFASLIFYCEKKIPGTK--FVDIPSSFWWAVVTMTTVGYGDMAPQSPSGKFIGSLCAVCGVLTIALPVPVIVNNFSLYYSHAQARLKLPKKRRR 403          

Query:  260 NRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQI-----LNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1534
            +R+I+N+GGFRHET  +TL+ IP TRLS + E     +    EYFFDRHP  F QVLN+YRTGKLH PT++CGP++EEEL FWG+D  Q+EPCCW TYT+HR  EE L+       ND+    D+ +++ + +   + E      +  W+++Q ++W   ++P+SS  +KI +  +  FI +SI +FC  T    R  N+                   + +   ++E  C+++F+ E+ +R +  PSK  F +  +N IDF+A++ FY++I   N           ++  F +IRIMRLF+  +   GL I++ T +AS  ELVLL+  + + +V+F++++YY E         F S+P+  WW ++TMTTVGYGDM P T+ G  +G  CAI GVL ++LP+ VI SNF+++Y+H QAR KLP K+RR
Sbjct:   16 SRIIINVGGFRHETSVSTLQNIPDTRLSWIAENSTVNEDNKREYFFDRHPTAFCQVLNFYRTGKLHCPTEMCGPMFEEELIFWGIDEKQMEPCCWGTYTQHREAEENLKAFVGPGFNDLK---DEPAENHMGSYGSINE------LNCWKRIQPQLWETLDEPHSSKMAKIFSYTSCLFIALSIATFCATTMPAIRKNNIMG-----------------SREGLDHIEMFCSIFFSFELFMRLISCPSKLHFCRGIMNWIDFVAIIPFYVNIFYPN----------PIVRMFLVIRIMRLFRFIKLSYGLQIMIQTLKASSHELVLLLLMVLIPMVMFSSIVYYVEVIIEGRGAQFTSVPESFWWCLITMTTVGYGDMTPQTWPGKIIGGACAICGVLIVALPISVIGSNFNLYYAHAQARLKLPVKQRR 409          

Query:  236 RGANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTE---ALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERF-------QHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRR 1534
            RG+  D   RVILN+GG+RHETY +TL+ +P +RL+ + E     A+YDP  NE FFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG++  Q+EPCCW  YT+HR  + TL+    +  DT+    D  Y       + Q   +Q       + WA+ E PYSS  ++I+A++++  I++S+ +FC+++           +  +D    A  K        F  +E +  +WFT E + R++  PSK  F+K+ +  +D L+++  Y+     +       + L+ L    ++RI RLF+  R ++G+ ++ HT RAS +EL LLV  L + +VIF+ L++YAE+        + NSK  F SIP   WWAI+TMTTVGYGD+ P T  G  +G LCA  GVL ++LPV VI SNF++FYSH QA+ KLPKK+ +
Sbjct:    1 RGSGKD---RVILNVGGYRHETYLSTLRVVPDSRLAWIGENASKQADYDPETNEIFFDRHPGVFANVLNYYRTGKLHCPGDVCGPLFEEELAFWGIEELQMEPCCWSNYTQHRDAQATLKAFEGLQKDTE----DSEYEAGERLARRQKTKMQ-------QFWALLEQPYSSKYAQILAMVSLVIIILSVTTFCIES-----------MPFAD----AFKKE-------FQILEILYCVWFTFEFVARAIACPSKVEFIKNFMTWVDVLSIIPLYISFAKGD-------QTLDFLFVLRLVRIFRLFRFFRTMSGMQVIGHTLRASARELFLLVLILLIPMVIFSTLVFYAEKSVSKFLNQRINSKGEFPSIPDAFWWAIITMTTVGYGDVTPKTPHGRFIGTLCACIGVLIVALPVSVIGSNFTLFYSHAQAQLKLPKKKHK 400          

Query:  254 SENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA---NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILN----DIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRV 1537
            ++ R+ LN+GG +HETY +T++  P TRL  + E +    +Y     E FFDRHP +F QVLNYYRTGKLH P DVCGPL+EEEL +WG+D  ++EPCCW TYT+HR  E  L+  N      DID+D+  + +  +K         G   +W K Q +IWAI E+P SS ++K   +++V  IV+S+ + C  T   F             +      S    +  F+ +EYIC +WFTIE+ +R L  P+K  F KS    +D L+++ FY+ +I  +          ++ +   +IR++RLF+  R + GL +++HT +AS  EL LL+  L + +V+F++++YY E+        F SIP+  WW+++TMTTVGYGDM P T+ G  +G  CAI GVL ++LP+ VI SNFS++Y+H QAR KLPKK+ ++
Sbjct:    8 TQKRITLNVGGQKHETYLSTIRNYPDTRLYWVVENVTKAIDYHSEKIELFFDRHPKIFDQVLNYYRTGKLHCPNDVCGPLFEEELAYWGIDEKEMEPCCWTTYTQHREAEHNLKSFNVTDFSTDIDSDRQEETETTSK-------AKGLHPFWVKYQPRIWAILEEPRSSRTAKAFWILSVLLIVLSVATACAITLPQF------------ATEGGSVSSESSAYVAFTVIEYICGVWFTIELGLRLLFCPNKRTFFKSYSFWVDVLSVIPFYVRLIFPH--------EHDLADALQVIRLLRLFRFFRLLYGLQVIMHTLKASSYELFLLLLILLIPVVLFSSIIYYVEKNIDGKTTKFRSIPESFWWSLITMTTVGYGDMTPRTWEGKIIGGACAIFGVLMVALPISVIGSNFSLYYAHAQARLKLPKKKTKI 415          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILN------------DIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTP 1570
            D ++R+++N+GG RH+TY++TL+ +P TRLS L E  A    +YD  + E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L                D + +  +   D++  +    +   +     W + Q ++WA+FEDPYSS  ++ +A+ ++FFI++SI +FCL+T   F  I N   +   DN +   +    +T    +Y+E +C +WFT E ++R    P+KF F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +        F +IP G WWA+VTMTT+GYGDM P T  GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ R +P  + +P +P
Sbjct:    5 DDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYARWIALASLFFILVSITTFCLETHEAFNPIVNRTYVEHLDNITTENTYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP-RAPQPGSP 467          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILN------------DIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFR-IPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTP 1570
            D ++R+++N+GG RH+TY++TL+ +P TRLS L E  A    +YD  + E+FFDRHPGVF+ +LNYYRTGKLH P DVCGPLYEEEL FWG+D   VEPCCWMTY +HR  EE L                D + +  +   D++  +    +   +     W + Q ++WA+FEDPYSS  ++ +A+ ++FFI++SI +FCL+T   F  I N   +   DN +   +    +T    +Y+E +C +WFT E ++R    P+KF F+++ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   N  +        F +IP G WWA+VTMTT+GYGDM P T  GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKK+ R +P  + +P +P
Sbjct:    5 DDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYARWIALASLFFILVSITTFCLETHEAFNPIVNRTYVEHLDNITTENTYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNRHIP-RAPQPGSP 467          

Query:  251 DSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDK-------VSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRI--PNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHN-------SKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTP 1585
            DSE ++++N GG RHETY++TLK +P TRLS LTE  A    +YDP  +E+FFDRHP  F+ +LNYYRTGKLH P+DVCGPL+EEEL FWG+D   VE CCWM Y +HR  EE L      + D  +        +  DL      E+  ++   Q W   Q  +WA+FEDPYSS  ++ VA  ++FFI++SI +FCL+T   F        N++V + +   I      T    +YVE +C +WFTIE++ R +  P K  F +S +NIIDF+A++ FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +       +   F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A+ KLPKKR + +P  + +P +P    P
Sbjct:    7 DSE-KIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPATFAFILNYYRTGKLHCPSDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPDAPEDDPALTGCADGDLKRLCMQEDGRRATRWQVW---QPWMWALFEDPYSSKYARYVAFASLFFILLSISTFCLETHEAFNTIYNKTENVTVGNFTHEEIVYEV-VTDGWLTYVEGVCVIWFTIEVMARVIFCPDKAEFFRSALNIIDFVAIVPFYLEVALSGLSSKTAKDILSFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPNDPTAAAHTTFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRNKHIP-RAPQPGSPNYCKP 465          

Query:  242 ANMDSENRVILNIGGFRHETYKATLKKIPATRLSKLTE---------------ALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRI----PNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKN-------HFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
               D   R+ILN+GG RHETYK+TLK +P TRL+ L                     Y+    +YFFDRHPGVF+ VLNYYRTGKLH P DVCGPL+EEEL FWG+D   VEPCCWMTY +HR  EE L +      + D+           +E+ H  G+   W K Q  IW +FEDPYSS +++ VA  ++FFI++SI +FCL+T   F       N+ N S  D     + +   +T    +YVE +C  WFTIE ++R    P K  F+K+ +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER    + +        F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:    2 GKFDDNERIILNVGGTRHETYKSTLKTLPGTRLALLASDSDIDSVLDQLQQVPGFIEYNARTKQYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGIDETDVEPCCWMTYRQHRDAEEALDVFELNVDNGDEDDDVGGGLG--IEDVHVDGNAGLWRKWQPVIWNLFEDPYSSRAARFVAFASLFFILVSITTFCLETHEAFNTIINKTNMRNNSCQD----LVPQYEIETDPALTYVEGVCVFWFTIEFLVRVTFCPVKLEFVKNVLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKANDPTASQHTKFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 442          

Query:  263 RVILNIGGFRHETYKATLKKIPATRLSKLTEALA----NYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKV------SKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRI--PNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHN-------SKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQA 1504
            ++++N GG RHETY++TLK +P TRLS LTE  A    +YDP L+E+FFDRHP VFS +LNYYRTGKLH P DVCGPL+EEEL FWG+D   VE CCWM Y +HR  EE L      + D          +  DL      E+  ++G   WW+  Q +IWA+FEDPYSS  ++ VA +++FFI+ISI +FC++T   F        N+++ + +   I      T    +YVE +C +WFTIE+++R    P K  F KS +NIIDF+A+L FYL++ LS +      + L  L     +RI+R+FKLTRH  GL +L HT RAS  E +LL+ FL + ++IFA ++YYAER   +       +  +F +IP G WWA+VTMTT+GYGDM P T+ GM VGALCA+ GVLTI++PVPVIV+NF M+YS   A
Sbjct:   37 KIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKLDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPDAPDDDPALGGADGDLKRLCMQEDARRAG---WWKTWQPRIWALFEDPYSSKYARYVAFMSLFFILISISTFCMETHEAFNTIYNKTENVTIGNVTREEIVYEV-VTDSWLTYVEGVCVIWFTIEVLLRVTFCPDKLEFFKSALNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMA 465          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNIASPIQRFVCVSTEKLSSNNSSFD 2047
            MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNI SPIQRFVCVSTEKLSSNNSSFD
Sbjct:   50 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNITSPIQRFVCVSTEKLSSNNSSFD 649          

Query:   39 LTIGYDFIRIEFDISIWTVLFKLNNLHALQIAIDLIFSIQV 161
            LTI     RIEFDISIWTVLFKL NLHALQIA DLIFSIQ+
Sbjct:   10 LTIVGSAERIEFDISIWTVLFKLKNLHALQIANDLIFSIQM 50          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNIASPIQRFVCVSTEKLSSNNSSFD 2047
            MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNI SPIQRFVCVSTEKLSSNNSSFD
Sbjct:   60 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNITSPIQRFVCVSTEKLSSNNSSFD 659          

Query:   33 RPLTIGYDFIRIEFDISIWTVLFKLNNLHALQIAIDLIFSIQV 161
            RPLTIGYDFIRIEFDISIWTVLFKL NLHALQIA DLIFSIQ+
Sbjct:   18 RPLTIGYDFIRIEFDISIWTVLFKLKNLHALQIANDLIFSIQM 60          

Query:  248 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNIASPIQRFVCVSTEKLSSNNSSFD 2047
            MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNI SPIQRFVCVSTEKLSSNNSSFD
Sbjct:    1 MDSENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKIVAVITVFFIVISILSFCLKTASHFRIPNLHNISVSDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNMWESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKELVLLVFFLCVFIVIFAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPKTPAGLTPLLSNPPFSLKNHPLNTIPSFTVGNRNELLPILNPTGDTISTLRSSPKKYKANSFFNMEGNKRRQNSTCSENHSFDNTELDRSHSIDIHLNPAIAIRPLLLKQRSPSQQSNKSYLSITGAINSVTAMEVSNITSPIQRFVCVSTEKLSSNNSSFD 600          

Query:  254 SENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---------SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNM-WESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPK 1564
            +++RVILNIGGFRHETYKATLKKIPATRLS+LTEALANYDP+LNE+FFDRHP VF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLD+NQVEPCCWMTYT++R+T+ETLQIL+DI++D D  S +D Y KFGLEEK+++  ++WW +++V+ W +FE+PYSSTS+K+VAVI++ FI+ SILSFCLKTA  FRIP + N S+         S+ ++W +  S  Q+H+ FSY+E ICN WF IEI +R + AP+K  F+KSP+NIID LAL+SF++D  LSN    S +  NLE+LEFFSIIRIMRLFKLTRHI+GLNIL+HTFRAS+KEL+LLVFFL VFIVIFAALMYYAERFQHN  N FNSIPQGLWWAIVTMTTVGYGDMVP TY+GM VGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK
Sbjct:    4 ADHRVILNIGGFRHETYKATLKKIPATRLSRLTEALANYDPILNEFFFDRHPAVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDANQVEPCCWMTYTQYRNTQETLQILDDIEVDPDG-SSEDRYIKFGLEEKYRNNTLKWWHRVKVQTWTMFEEPYSSTSAKMVAVISISFIIFSILSFCLKTAPRFRIPTISNKSLTVILNDAHRSNLTTWYLVNSFYQSHKYFSYIEAICNSWFIIEIFVRFVSAPTKLEFIKSPINIIDILALVSFFVDTFLSNTELLSEKFHNLEVLEFFSIIRIMRLFKLTRHISGLNILLHTFRASMKELILLVFFLIVFIVIFAALMYYAERFQHNKYNDFNSIPQGLWWAIVTMTTVGYGDMVPKTYMGMMVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK 449          

Query:  254 SENRVILNIGGFRHETYKATLKKIPATRLSKLTEALANYDPVLNEYFFDRHPGVFSQVLNYYRTGKLHYPTDVCGPLYEEELEFWGLDSNQVEPCCWMTYTRHRSTEETLQILNDIDIDTDKVSKDDLYAKFGLEEKHQSGDIQWWEKLQVKIWAIFEDPYSSTSSKXXXXXXXXXXXXXXLSFCLKTASHFRIPNLHNISV---------SDNSSWAISKSSPQTHQIFSYVEYICNLWFTIEIIIRSLVAPSKFIFLKSPVNIIDFLALLSFYLDIILSNM-WESGQMENLEMLEFFSIIRIMRLFKLTRHIAGLNILVHTFRASLKEXXXXXXXXXXXXXXXAALMYYAERFQHNSKNHFNSIPQGLWWAIVTMTTVGYGDMVPHTYIGMTVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVESVRPK 1564
            +++RVILNIGGFRHETYKATLKKIPATRLS+LTEALANYDP+LNE+FFDRHP VF+Q+LNYYRTGKLHYPTDVCGPL+EEELEFWGLD+NQVEPCCWMTYT++R+T+ETLQIL+DI++D D  S +D Y KFGLEEK+++  ++WW +++V+ W +FE+PYSSTS+K+VAVI++ FI+ SILSFCLKTA  FRIP + N S+         S+ ++W +  S  Q+H+ FSY+E ICN WF IEI +R + AP+K  F+KSP+NIID LAL+SF++D  LSN    S +  NLE+LEFFSIIRIMRLFKLTRHI+GLNIL+HTFRAS+KEL+LLVFFL VFIVIFAALMYYAERFQHN  N FNSIPQGLWWAIVTMTTVGYGDMVP TY+GM VGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVE+VRPK
Sbjct:   29 ADHRVILNIGGFRHETYKATLKKIPATRLSRLTEALANYDPILNEFFFDRHPAVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDANQVEPCCWMTYTQYRNTQETLQILDDIEVDPDG-SSEDRYIKFGLEEKYRNNTLKWWHRVKVQTWTMFEEPYSSTSAKMVAVISISFIIFSILSFCLKTAPRFRIPTISNKSLTVILNDAHRSNLTTWYLVNSFYQSHKYFSYIEAICNSWFIIEIFVRFVSAPTKLEFIKSPINIIDILALVSFFVDTFLSNTELLSEKFHNLEVLEFFSIIRIMRLFKLTRHISGLNILLHTFRASMKELILLVFFLIVFIVIFAALMYYAERFQHNKYNDFNSIPQGLWWAIVTMTTVGYGDMVPKTYMGMMVGALCAITGVLTISLPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEAVRPK 474