mitochondrial sodium/calcium exchanger protein

Query: 1323 ISDVQNQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTIL-PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            +SD +  R  SN +     +  D+   L F   T    L+  L P+D   W R S + K L + + P+ F+L LT+ VV+ D   + W + LNCLH V+SPL+ +  +      +    G +  +++++I   A  SV   + S+S PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++ ++    + L+ D +   VL   + L    +L+ +P+  F+++++YG  LL  Y+ F ++ +
Sbjct:  214 LSDSEEDRVSSNTN---SYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVAL 516          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP--TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSA 446
            + + G N S+ C +++    C  D G+L+Y E  +C F   ++P    L + W L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A
Sbjct:   54 RKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVA 160          

Query: 1323 ISDVQNQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTIL-PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            +SD +  R  SN +     +  D+   L F   T    L+  L P+D   W R S + K L + + P+ F+L LT+ VV+ D   + W + LNCLH V+SPL+ +  +      +    G +  +++++I   A  SV   + S+S PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++ ++    + L+ D +   VL   + L    +L+ +P+  F+++++YG  LL  Y+ F ++ +
Sbjct:  270 LSDSEEDRVSSNTN---SYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVAL 572          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP--TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDR-RLDSSKCKANKNCSHDPL 869
            + + G N S+ C +++    C  D G+L+Y E  +C F   ++P    L + W L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLALG++ GAG+LV T+ AG I I+ PF    RP  +DI+FY++A+    ++L R ++    ++ +L +Y+ YV    +   +Y      Q+Q R      + VT  ++ +++  R+ S+    +    + PL
Sbjct:   54 RKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIY------QRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPL 294          

Query: 1323 ISDVQNQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTIL-PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            +SD +  R  SN +     +  D+   L F   T    L+  L P+D   W R S + K L + + P+ F+L LT+ VV+ D   + W + LNCLH V+SPL+ +  +      +    G +  +++++I   A  SV   + S+S PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++ ++    + L+ D +   VL   + L    +L+ +P+  F+++++YG  LL  Y+ F ++ +
Sbjct:  270 LSDSEEDRVSSNTN---SYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVAL 572          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP--TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDR-RLDSSKCKANKNCSHDPL 869
            + + G N S+ C +++    C  D G+L+Y E  +C F   ++P    L + W L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLALG++ GAG+LV T+ AG I I+ PF    RP  +DI+FY++A+    ++L R ++    ++ +L +Y+ YV    +   +Y      Q+Q R      + VT  ++ +++  R+ S+    +    + PL
Sbjct:   54 RKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIY------QRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPL 294          

Query: 1323 ISDVQNQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTIL-PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGL 2027
            +SD +  R  SN +     +  D+   L F   T    L+  L P+D   W R S + K L + + P+ F+L LT+ VV+ D   + W + LNCLH V+SPL+ +  +      +    G +  +++++I   A  SV   + S+S PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL
Sbjct:  140 LSDSEEDRVSSNTN---SYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGL 375          

Query:  363 LRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDR-RLDSSKCKANKNCSHDPL 869
            L++S N+AGVT LA GNGA D+FS+L A   S+    GLALG++ GAG+LV T+ AG I I+ PF    RP  +DI+FY++A+    ++L R ++    ++ +L +Y+ YV    +   +Y      Q+Q R      + VT  ++ +++  R+ S+    +    + PL
Sbjct:    3 LKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIY------QRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPL 164          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP--TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEF-WS 659
            + + G N S+ C +++    C  D G+L+Y E  +C F   ++P    L + W L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLALG++ GAG+LV T+ AG I I+ PF    RP  +DI+FY++A+    ++L R ++   W+
Sbjct:   54 RKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWA 230          

Query: 1455 DLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMN-PIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL---INLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLI 2240
            + +DW  +++F K++A +      +  LTI + E       W K L  LH    P   +  I   +  P      +  Y + +  +LA + +  T  S  P  Y+  +++ GFI SI WIY I +E+VNV+  LGVV  +   +LGL+ILA++NS+GDL++++++ K+ YPR+A AA IGGPLFNLL+G GLPF+I   Q   +   IN     ++L   ISL+ T  LI +P+ KFR+ + +  +L++IYI F + +I   T ++
Sbjct:  411 EAEDWEEMNIFSKVMAYINVVPNLLFKLTIPLNE-----MSWSKPLTLLHAFTCPAFLLFSIQFFLETPFSGSPGLWVYGLAVSIVLAILIMVFTELSVQPKYYKEIYSYSGFIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFTIAKLQGKYISMTINPTYRLLILFLAISLLAT--LIGIPVQKFRLQRPHAAVLISIYIAFIVFVILSETGVL 669          

Query:  165 CQYVK-NVSACLFDSGFLNYFEWQYCGFD--SRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTI-ILLRRKIEFWSSIVFLSIYIVYVFVTAISRALY-LKLKKCQKQ 752
            C YV  N +AC    G+L + ++  C     SR++  I+ +++ LVL + V++ AD FF+P +  +   LR+S+++AGVT +A GNGA DVF S++++LSS  P   LALG + G G+ V T+    I++  PF++     I+D++FYL+AL +     +   ++  W  + FL +Y++YV     ++A++  K K  QKQ
Sbjct:   56 CDYVNCNDNACE-GGGYLLWTQYVECASSTFSRVILIIVGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIASVLSSPTPKADLALGELFGGGLFVTTMVVSTIILTSPFDVEVFSTIRDLLFYLVALSFLAFCFVFYNRVTLWMPLTFLGLYLLYVITVIGAQAVHNRKRKALQKQ 255          

Query: 1458 LDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHV-NMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQK---PILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILI 2216
            +D+W  +++F+K++A++ +   F+  LTI   E+      W K +  L C++ P+  +  I V +++P      +  Y +++  LL    +  T     PP Y+   ++ GF+ SI WIY I +E+VNV+  LGVV  +   +LGL+ILA++NS+GDL++++++AK+ YPR+A AA IGG LFNLL+G GLPF+I   Q     ++IN     ++L   ISL+ T  LI +   K+ + +I+   L+ IYI FF+ I
Sbjct:  330 MDEWDEMNIFQKVIAVLNTIPNFLFKLTIPHSEQP-----WSKPITLLQCLICPVFLLFCIQVCSISPFPNSPGLWMYGLILSVLLTAAVLFFTELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTIAKIQGKSISMIINPTYRLLMLFLAISLIFT--LIAMFAQKYFLRRIHSYSLVFIYISFFVFI 579          

Query:  114 MESCNPKN------ITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDS--RIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILL-RRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENI 773
            +E C P +        G N +  C+YVK         G++ +  +  C      RI+  I  +++ LVL + V++ AD FF+P +  +   LR+S+++AGVT +A GNGA DVF +++++LSS  P   LALG + GAG+ V T+   + +   PF+      I+DI FYL+AL +     +    +E W  I FL +Y++YV    +S+ L+ + KK +++   ++ +
Sbjct:   42 IEKCIPDDGEQCTIQAGWNSTQVCEYVKCNDDNCEGGGYVLWTRYVECASSPAVRIILIITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEVFSSIRDIAFYLVALAFLAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHNRHKKDEEKVDEVKTV 270          

Query: 1461 DDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHV-NMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQK---PILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILI 2216
            D++  +++F KI+ +++   +F   LT+   E       WCK L  LHC  S    +  I +  + P      +  Y +    +LA +++     S     Y+  ++++GF+ SI WIY   NEIV+V+  +GVV  +   +LGL+I+A++N +GD+V++I + K+ YP++A AA IGGPLFNLL+G GLPF+I  AQ     +LIN     ++L   ISLVTT   + L I +F V + + ++L+ I++VF I I
Sbjct:  442 DEFSEMNIFIKIVTVIKVVPVFFFKLTVPSNE-----MSWCKPLFILHCFASIQFALFSIQIITLKPFDGSPGLWLYGLGFSAILAMVAMYFLPLSKEQKYYKEIYSYLGFLMSIAWIYATSNEIVSVVTMIGVVTGLSMELLGLTIMAWSNCIGDIVADIAVVKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIAAAQGKEMELLINPVYRLLMLFLGISLVTT--FVALFIQRFTVRRPHAVLLIFIFVVFLIFI 690          

Query:  156 SNECQYVK-NVSACLFDSGFLNYFEWQYCGFD--SRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLR-RKIEFWSSIVFLSIYIVYVFVTAISRALY 725
              +C+Y+K N  +C    G+L +  +  C ++   R++  IL IL+ ++L + +++ AD FF P +  +   LRMS+++AGVT LA GNGA DVFSS+S++L++  P   LALG + G  I V T+   II+    F++   P ++D+IFY+  L +     L+  KIE W    FL IY VYV VT I   +Y
Sbjct:   66 EEKCEYIKCNQDSCE-GGGYLTWSHYVKCQYNIGVRVILIILGILYLIILFVIMSSIADDFFCPAISGIVSHLRMSESIAGVTFLAFGNGAPDVFSSISSVLTTPKPKADLALGDLFGTSIFVTTVVLAIIIFTKSFKVAIIPTLRDLIFYMTTLAFIVFCFLKFDKIEVWMPATFLGIYGVYV-VTVIILGIY 257          

Query: 1458 LDDWP------RLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHV-NMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKP---ILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIIL 2183
            L  WP       +++F KI+ I++    F + +TI   E       WCK L  LHC  S    +  I + N+ P      +  Y +     +A +++     +     ++  ++++GF+ SI WIY   NEI++V+  +GVV  + Q +LGL+++++++ +GD+V++I + K+ YP++A AA IGGPLFNLL+G GLPF+I +AQ     ++IN     ++L   ISLVTT   + L I +F V   + + L
Sbjct:  437 LKPWPSREEFSEMNIFVKIIMIIRIIPSFFMKMTIPSNE-----MSWCKPLFLLHCFASIQFALFSIQIINLKPFDGSPGLWLYGLAFSATIALLALCFLPLNKELKYHKEVYSYLGFLMSIAWIYATANEIISVMTMVGVVTGLSQELLGLTVMSWSDCIGDIVADIAVIKQGYPKMAMAAAIGGPLFNLLIGFGLPFTIASAQGKQIDLIINPVYRILLLFLGISLVTT--FVALFIERFTVRWPHAVAL 681          

Query:  144 GTNYSNECQYVK-NVSACLFDSGFLNYFEWQYCGFD--SRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLR-RKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIEN 770
            G     +C Y+K N  +C    G+L +  +  C ++  +R+V  I+ I++ + L + ++T AD FF P +  +   L+MS+++AGVT LA GNGA DVF S+S++LS+  P   LALG + G  I V T+   II+    F++   P ++D+IFY+I L + T   L+  KIE W    FL IY VY+ +T I+ ++Y   +K  K+++ +E+
Sbjct:   63 GWTSEEKCAYIKCNQDSCE-GGGYLTWSHYVKCQYNIGARVVLIIVGIIYLIFLFVVMSTIADDFFCPSISGIVTHLKMSESIAGVTFLAFGNGAPDVFGSISSVLSTPKPKAALALGDLFGTSIFVTTVVLAIIIFTKSFKVAIIPTLRDLIFYMITLAFITFCFLKFDKIEVWMPATFLGIYAVYL-LTVIAFSIYRTRRKNLKKKKQLES 273          

Query: 1461 DDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNM-NPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLF-----------------NLLVGIGLPFSI---KTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            D++  ++ F + + +V     F L LTI   E       W K +  +HC  S  + +  + ++  +P      +  Y +LI  +L+ +++  T        Y+  ++++GF+ SI WIY I +EI+NV+  +GV   + Q ILGL+I+A++N +GD+VS++ + K+ +P++A AA IGGPLF                 +LL+G GLPF+I   +  Q  ++I      ++L   ISL T+  LI + + +F+V   + + LLT+++ F I ++
Sbjct:  275 DEFYEMNYFSRFITVVAVIPTFFLKLTIPSNE-----MPWSKPILIIHCFCSIQLALFAVQISAKSPFHGSPGLWLYGLLISIILSLLALRFTPLDREQKYYREVYSYLGFLMSIAWIYTISSEIINVITMIGVATGVSQEILGLTIMAWSNCIGDIVSDVAVVKQGFPKMAMAAAIGGPLFSKLYSRPCQIKITTYISDLLIGFGLPFTIACLQGKQIDLIITPVYRLLMLFLAISLFTS--LIAIFVQRFKVRWPHAVALLTVFVAFLIFVL 541          

Query:  318 ADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLR-RKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIEN 770
            AD FF+P +  + + L++S+++AGVT LA GNGA DVF S+++++++  P   LA+G I+G GI V T+    I++   F I     I+DI+F++IA ++  I  L    +E W  + FL +Y  YV V+ I   L  K +K  + E+ IEN
Sbjct:    5 ADDFFSPSIAGIVRHLKISESIAGVTFLAFGNGAPDVFGSIASVITTPKPKADLAIGDIIGGGIFVTTVVLSAIILTKSFRIAILATIRDIVFFIIADIFLAIWFLTFNHVEIWMPLTFLGLYAAYV-VSVILMRLNSKRRKRARHEK-IEN 154          

Query: 1281 EFKNIAVEKLKKKSISDVQNQRTESNLSRI-LQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIG-----TDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLK-----SDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLIN 2243
             F N+         I + +++  +  L+R  L  + N  +  L     F  F  ++ PVD + W       +I  I + P++F+L L I VV+ +    GW K+LNC   V +P + IT +H  ++ +      T  F ++     + +   I + + S+++ PP Y   F  + F +S+  ++  V E+  +   +G+VF++ ++ + ++  A +N+  D+++N  LA + Y R+A+AA IGGP+F +LV + L F      + +  N        D   L   I++VTTM   V     F   +  G+ L  +Y+ F +  +    ++++
Sbjct:  285 HFSNMTSSGYFVTPIPERRSEHVDYELNRTALHDSENPKNLQL-----FTEFFQSLNPVDAEAWQLGGWSNRIYLIARCPLVFVLQLFIPVVDYEKIKHGWSKLLNCTQIVTNPFVVITLVHSGVSSVYKTWHITLDFSISMWSPCLTVPLAIVIFLHSRTDVPPSYHHLFIILTFFSSMVTLWLAVTELEVLSEIVGIVFNLSESFMAVTFEAVSNATPDIIANYQLALQGYGRMAFAAIIGGPVFAILVSMSLAFIFNHRVREVGANSWVYGDLGDNCYLFLVITIVTTMWWSV--TFDFHARRSAGVFLWLVYLQFLLYAVCVEWDVVH 609          

Query: 1230 KIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPL----IWITFIHVNMNPI-----------GTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLV 2015
            K+ +YS DT +    +E+  +I++ +++  ++  ++N R   N  R    N   D +     G F+ F L + P+    W +  +  ++L ++++P + I TL I +V+ ++   GW K+LN ++ V++P     I+++F+H   N +           G   F++T       +   + +   ++++ PP Y   F  M    S+F I+    EI  VL  +G + SI    +G ++ AF  ++G L +N  +A   YP++A+A+ IGG  F ++V
Sbjct:  268 KLEYYSQDTRVEI--LEKSSSISITRIRYTTMRMIRNPRVSVN--RRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQNTLIYGASSFVLT-------VPFAVFILFHARTDVPPSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFTIVV 533          

Query:  315 TADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAI-----LSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDI 590
            T + +++P L  V++ L M+++LAGVTL+A GN +AD F++L+++     + +NN          L + + V TI+ G+I  I PF++     ++DI
Sbjct:  100 TINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLASVERHVPVFANN----------LSSALFVITISGGLIFYISPFKMNSYETVRDI 186          

Query: 1416 GTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVA--------ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVG----------IGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILI 2216
            G FK   + + P++ + W + ++ K+   + + P + I  + I +V+ ++   GW K+LNC+  +L+P + I  I   ++  G   + V      I  +  + +         I S+++ PP Y   F  M    S+F I+    EI  VL  +G +  +    +G ++ A   S+G L++N+ +A   YPR+AYA+ IGGP F +++            GLP S         +N      + VF+  L +T     L     R   I+ I+   IY++F ILI
Sbjct:  316 GLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTGNYGLNAFIFLNLGVFSTLLWST----TLGFFARRSVGIFSIVFYCIYLLFAILI 596          

Query:  321 DSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLI-ALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAI 710
            + +++P L  V++ L M++++AGVTLLA GN +AD+FS+L+++    N NV     + L A + V+ ++ G+I    PF++     ++DI+F +  ++L    +     +   S IV   +YI Y+ V  +
Sbjct:   94 NKYYSPALKAVSRFLCMNEHVAGVTLLAFGNSSADLFSNLASV----NANV-PVFANSLAAALFVSMVSGGLICYTSPFKMNAYESVRDILFLIFGSMLLQYFLASSAHVPETSFIVMFLVYIFYILVNVV 219          

Query: 1416 GTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVA--------ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVG----------IGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILI 2216
            G FK   + + P++ + W + ++ K+   + + P + I  + I +V+ ++   GW K+LNC+  +L+P + I  I   ++  G   + V      I  +  + +         I S+++ PP Y   F  M    S+F I+    EI  VL  +G +  +    +G ++ A   S+G L++N+ +A   YPR+AYA+ IGGP F +++            GLP S         +N      + VF+  L +T     L     R   I+ I+   IY++F ILI
Sbjct:  207 GLFKDLFIALRPINCEKWRKGNIIKRAFMLTKIPAVIICCIYIPLVDYELDKHGWNKLLNCIQVMLNPAMSIMAIKALLSSRGNSLWYVAMGEEAIYAMYSLPITVPIAVFMFIQSRTDVPPFYHSVFTVMNLTGSMFMIFICATEIDKVLEVIGHILKVEDDFMGATVKACTGSLGPLIANVAMALHGYPRMAYASAIGGPFFTVVMSASTVMHVKNLFGLPVSEANQTGNYGLNAFIFLNLGVFSTLLWST----TLGFFARRSVGIFSIVFYCIYLLFAILI 487          

Query: 1329 DVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSP-----LIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIK----TAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFI 2210
            DV+  R      RIL S  N  + FL     F  FL  I P+D + W       +IL I+++P+  +L L + +V+  +   GW K+LNCL  VL+P     L+    +H          F +    L++ +   I V + S+++ PP Y   +  +   T I + +    E+  ++  +GVVF +  + + ++  + + +  DL++   LAK  Y ++A+ A IGG +++L V +G+   ++    +  + +L      T+ +   I++ TT+   +     F   +  G+ + +++++F +
Sbjct:  299 DVETNR------RILHSKANPKNLFL-----FSEFLQAINPIDSEGWYLSGTCARILQILKAPVTLMLHLVVPLVDYQLVKHGWSKMLNCLQIVLTPFVIFALVETMLVHKYAEWYYVPQFRMAIWSLLVTMPLAIVVFLHSRTDIPPFYHSSYCALTISTVIIFFWICAWEMDALISIIGVVFDLAPSYMSITFNSVSAATADLIAYAHLAKHGYGKMAFGAIIGGSVYSLAVNVGIELVLQKKLNSRGQVVLYGDDGVTIYIFLVITITTTLWWCL--TFNFVARRSAGLFMWSLFVLFLV 588          

Query:  156 SNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP---TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERP 761
            S  C+YVKN   C  D GF+ Y    +C F   ++P   TI +I    + L+     +D FF P L  +   LR++ N+AGVT LALGNGA DVFS+++A   S+    GLA+G++ GAGI V T+ AG + ++ PF +  RP ++D+IFY+ A+ W   +L +  I    S+ +L +YI YVF   +S  +Y + +K Q  E P
Sbjct:   64 SQRCEYVKNTPDCASDEGFIKYPFVTFCLFTPSLLPLAITIYVIWLLFLFLVLGLIASD-FFCPNLSAIASTLRLTHNVAGVTFLALGNGAPDVFSAMAAF--SHPQTAGLAIGALFGAGIFVTTVVAGSVALVKPFTVASRPFLRDVIFYMAAVFWTFTVLYKGHISLGESVGYLGMYIAYVFTVILSSYIYNR-QKHQLTESP 264          

Query: 1782 MGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNK--------IYGIILLTIYIVFFILI 2216
            + F  S  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+G+P+ I+T        +K ++  LV+++ L+  +  + L +L   VN+        IY ++L  I++ F I+I
Sbjct:  434 LSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGIQTMAVNYGSVVKINSRGLVYSVVLL--LGSVALTVLGIHVNRWRLDLRLGIYVLVLYAIFLTFSIMI 584          

Query: 1734 TSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTIS-LVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF--FILIISF 2225
            T  +++ P ++ ++  + FI+S  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++L+G+GLP++++T        +  ++  L+F++  L+ ++ L VL +    ++++K  G   L +Y VF  F ++I F
Sbjct:  429 TVPNSANPRWERWY-MVSFISSTIWIAFFSYIMVWMVTVIGYTMGIPDVIMGITFLAAGTSVPDCLASLIVARQGMGDMAISNSIGSNVFDILIGLGLPWALQTLAINYGSTIHLNSKGLIFSVGLLLASVFLTVLGVHLNNWKLDKRLGFACLLMYAVFLCFSILIEF 596          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTN 791
            ++A   D +F P L  + + L +S+++AG T +A G+ A ++F+S+  +  +   +VG+          ++  I    I       +    +++D  +Y IA+    + +   K+ +W S++ + +Y+VY+ +   +  +   +++ +K    + N   S T+
Sbjct:   88 ALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKG-DVGVGTIVGSAVFNILCIIGVCGIFTAQAVRLSCWTLMRDSTYYTIAVATLIVFIYDEKVTWWESLILIVLYLVYILIMKFNSRVVHFIERRKKNPANLGNGTASNTD 249          

Query: 1752 PPIYQPF---FAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKT----AQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLIN 2243
            P   +PF   F  + F+ S  WI      +V ++  +G    IP T++G+++LA   S+ D V+++ +A+     +A +  +G  +F++L  +GLP+ I+T       P+ +N  S  V +  T+ L      + + I  ++++   G++ L  YI+F  L I +   +I 
Sbjct:  336 PDCRRPFWKNFYMLTFLMSAVWISAFTYVLVWMVTIVGETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDMLC-LGLPWFIQTVFVDVGSPVDVN-SSGLVFMSCTLLLSIIFLFLAVHINGWKLDWKLGLVCLACYILFATLSILYELGIIG 504          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRR--------PIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYV----FVTAISRALYLKLKKCQ 746
            S+A   D FF P L V+T  L +S ++AG T +A G  A ++F+SL  +  S++ NV        G G +V +    I+ +I    +  R        P+ +D+ FY++ L+   I  L   I +W S++ +  Y +YV    F   + RA   +L K +
Sbjct:  183 SLAIVCDEFFVPTLGVITDKLAISDDVAGATFMAAGGSAPELFTSLIGVFISHS-NV--------GIGTIVGSAVFNILFVIGMCALFSREMLHLTWWPLFRDVSFYILDLIMLIIFFLDNTIMWWESMMLVGGYALYVTFMKFNVQLERAFKSQLSKHK 333          

Query: 1755 PIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP---FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLI 2240
            P  + FF    F+ SI WI      +V     +G    I + I+GL+ILA   S+ DL++++ +A++    +A ++ +G  +F++ +G+ +P   FS   +  P+ ++  +     +  + L+    +I +   K+R+NK+ G  +  +Y VF +L +     +I
Sbjct:  556 PASKKFFVIT-FLGSIVWIAIFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITMGLPVPWLMFSFFHSFAPVPVS-SNGLFCAIVLLFLMLLFVIISIAACKWRMNKVLGFTMFILYFVFLVLSVMLEDRII 718          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIG---TDGFIVTYXXXXXXXXXXXSVA-ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVF 2204
            PVD   W + S   +   +++ P+  +L LT+ VV+ D   + W + LNCLH + +PL+ +    +N    G    +G I  + +L+I      +V  +T+ +  PP Y   F+F+GF+ S  WI     EIVN+L T GV+F +  T+LGL++LA+ NS+GD VS+ITLA++ YPR+A++AC GG +FN+L+G+GL   ++       + L+   +   +L   + +    +LI +P   F + + YG+ L  IY VF
Sbjct:  300 PVDSRKWKQKSWKWRTFKLIKVPVEILLLLTVPVVDPDKEEQNWQRPLNCLHLITTPLLCV--FTINAGSYGLYIINGVIPVWAVLLIIGTFLAAVVFLTTTNGEPPKYHCLFSFLGFVASALWISAAATEIVNLLRTFGVIFRLSNTVLGLTLLAWGNSIGDFVSDITLARQGYPRMAFSACFGGIIFNVLIGVGLGCLLQMGPSRTSLQLEHQGLLVWILAGGLGISLVFSLISVPAQSFHLRRGYGVALFFIYAVF 556          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSV--ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQ 746
            + +   + S  C + +    C    G++NY +  +C F   + P  + +    +L L +  A TA+ FF P L  +++ILR+S N+AGVT LA GNGA DVFS+++A   S++   GLA+G++ GAG+ V T+ AG I I+ PF    RP ++DI+FY+ A+     IL +  +    ++V+L +Y+VYVFV  IS  +Y ++++ Q
Sbjct:   44 QEVGKLDASLRCNFTRTTPDCSVGDGYINYLDGAFCSFLPSLFPLAIFLYTLWLLYLFIILAVTAEKFFCPNLSAISRILRLSHNVAGVTFLAFGNGAPDVFSAVAAF--SDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAIFLTFFILYQGFVTLAEALVYLLLYLVYVFVVVISTWIYRRMRQQQ 248          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIG---TDGFIVTYXXXXXXXXXXXSVA-ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVF 2204
            PVD   W + S   +   +++ P+  +L LT+ VV+ D   + W + LNCLH + +PL+ +    +N    G    +G I  + +L+I      +V  +T+ +  PP Y   F+F+GF+ S  WI     EIVN+L T GV+F +  T+LGL++LA+ NS+GD VS+ITLA++ YPR+A++AC GG +FN+L+G+GL   ++       + L+   +   +L   + +    +LI +P   F + + YG+ L  IY VF
Sbjct:  311 PVDSRKWKQKSWKWRTFKLIKVPVEILLLLTVPVVDPDKEEQNWQRPLNCLHLITTPLLCV--FTINAGSYGLYIINGVIPVWAVLLIIGTFLAAVVFLTTTNGEPPKYHCLFSFLGFVASALWISAAATEIVNLLRTFGVIFRLSNTVLGLTLLAWGNSIGDFVSDITLARQGYPRMAFSACFGGIIFNVLIGVGLGCLLQMGPSRTSLQLEHQGLLVWILAGGLGISLVFSLISVPAQSFHLRRGYGVALFFIYAVF 567          

Query:  105 RKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSV--ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQ----ERPIENIE 776
            + + + C  + +   + S  C + +    C    G++NY +  +C F   + P  + +    +L L +  A TA+         ++    ++  L GVT LA GNGA DVFS+++A   S++   GLA+G++ GAG+ V T+ AG I I+ PF    RP ++DI+FY+ A+     IL +  +    ++V+L +Y+VYVFV  IS  +Y ++++ Q      E P E+ +
Sbjct:   57 KHISQQC--QEVGKLDASLRCNFTRTTPDCSVGDGYINYLDGAFCSFLPSLFPLAIFLYTLWLLYLFIILAVTAEK-----NQTISMQCSLTFFLHGVTFLAFGNGAPDVFSAVAAF--SDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAIFLTFFILYQGFVTLAEALVYLLLYLVYVFVVVISTWIYRRMRQQQLAVPITEEPGEDFK 277          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIG---TDGFIVTYXXXXXXXXXXXSVA-ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVF 2204
            PVD   W + S   +   +++ P+  +L LT+ VV+ D   + W + LNCLH + +PL+ +    +N    G    +G I  + +L+I      +V  +T+ +  PP Y   F+F+GF+ S  WI     EIVN+L T GV+F +  T+LGL++LA+ NS+GD VS+ITLA++ YPR+A++AC GG +FN+L+G+GL   ++       + L+   +   +L   + +    +LI +P   F + + YG+ L  IY VF
Sbjct:  287 PVDSRKWKQKSWKWRTFKLIKVPVEILLLLTVPVVDPDKEEQNWQRPLNCLHLITTPLLCV--FTINAGSYGLYIINGVIPVWAVLLIIGTFLAAVVFLTTTNGEPPKYHCLFSFLGFVASALWISAAATEIVNLLRTFGVIFRLSNTVLGLTLLAWGNSIGDFVSDITLARQGYPRMAFSACFGGIIFNVLIGVGLGCLLQMGPSRTSLQLEHQGLLVWILAGGLGISLVFSLISVPAQSFHLRRGYGVALFFIYAVF 543          

Query:  105 RKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSV--ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSI----VFLSIYIVYVFV 701
            + + + C  + +   + S  C + +    C    G++NY +  +C F   + P  + +    +L L +  A TA+         ++    ++  L GVT LA GNGA DVFS+++A   S++   GLA+G++ GAG+ V T+ AG I I+ PF    RP ++DI+FY+ A+     IL +  +    ++     +   Y++Y F+
Sbjct:   57 KHISQQC--QEVGKLDASLRCNFTRTTPDCSVGDGYINYLDGAFCSFLPSLFPLAIFLYTLWLLYLFIILAVTAEK-----NQTISMQCSLTFFLHGVTFLAFGNGAPDVFSAVAAF--SDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAIFLTFFILYQGFVTLAEALGKYKAYFLAYLLYCFL 252          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIG---TDGFIVTYXXXXXXXXXXXSVA-ITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVF 2204
            PVD   W + S   +   +++ P+  +L LT+ VV+ D   + W + LNCLH + +PL+ +    +N    G    +G I  + +L+I      +V  +T+ +  PP Y   F+F+GF+ S  WI     EIVN+L T GV+F +  T+LGL++LA+ NS+GD VS+ITLA++ YPR+A++AC GG +FN+L+G+GL   ++       + L+   +   +L   + +    +LI +P   F + + YG+ L  IY VF
Sbjct:  303 PVDSRKWKQKSWKWRTFKLIKVPVEILLLLTVPVVDPDKEEQNWQRPLNCLHLITTPLLCV--FTINAGSYGLYIINGVIPVWAVLLIIGTFLAAVVFLTTTNGEPPKYHCLFSFLGFVASALWISAAATEIVNLLRTFGVIFRLSNTVLGLTLLAWGNSIGDFVSDITLARQGYPRMAFSACFGGIIFNVLIGVGLGCLLQMGPSRTSLQLEHQGLLVWILAGGLGISLVFSLISVPAQSFHLRRGYGVALFFIYAVF 559          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSV--ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIEN 770
            + +   + S  C + +    C    G++NY +  +C F   + P  + +    +L L +  A TA+ FF P L  ++    ++  L GVT LA GNGA DVFS+++A   S++   GLA+G++ GAG+ V T+ AG I I+ PF    RP ++DI+FY+ A+     IL +  +    ++V+L +Y+VYVFV  IS  +Y ++++ Q+   PI  
Sbjct:   47 QEVGKLDASLRCNFTRTTPDCSVGDGYINYLDGAFCSFLPSLFPLAIFLYTLWLLYLFIILAVTAEKFFCPNLSTISMQCSLTFFLHGVTFLAFGNGAPDVFSAVAAF--SDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAIFLTFFILYQGFVTLAEALVYLLLYLVYVFVVVISTWIYRRMRQ-QQLAVPITE 258          

Query:  156 SNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSV--ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLR 638
            S  C + +    C    G++NY +  +C F   + P  + +    +L L +  A TA+ FF P L  +++ILR+S N+AGVT LA GNGA DVFS+++A   S++   GLA+G++ GAG+ V T+ AG I I+ PF    RP ++DI+FY+ A+     IL +
Sbjct:   51 SLRCNFTRTTPDCSVGDGYINYLDGAFCSFLPSLFPLAIFLYTLWLLYLFIILAVTAEKFFCPNLSAISRILRLSHNVAGVTFLAFGNGAPDVFSAVAAF--SDSRTAGLAIGALFGAGVFVTTVVAGGITIVKPFTAASRPFLRDIVFYISAIFLTFFILYQ 211          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSN-SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL-INLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            P+D   W   S+  ++L +V+ P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SN  PP     FAF+GF+TS  WI     E+VN+L +LGV+F +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++  +  ++ + L+ D +   VL   + L    +L+ +P+  F+++K YG+ LL  YI F ++++
Sbjct:  255 PLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVL 517          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXX--XXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSA 446
            SV +  M  C  + + G N S+ C +V+    C  ++G+L+Y E  +C F   ++P  + +     L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A
Sbjct:   44 SVNQTAMADC--RAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVA 160          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSN-SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL-INLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            P+D   W   S+  ++L +V+ P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SN  PP     FAF+GF+TS  WI     E+VN+L +LGV+F +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++  +  ++ + L+ D +   VL   + L    +L+ +P+  F+++K YG+ LL  YI F ++++
Sbjct:  294 PLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVL 556          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKK 740
            SV +  M  C  + + G N S+ C +V+    C  ++G+L+Y E  +C F   ++P              +A T   F+   L ++  +   ++   GVT LA GNGA D+FS+L A   S+    GLA+G++ GAG+LV T+ AG I I+ PF    RP ++DI FY++A+      L   +I    ++ +L +Y+ YV    I   +Y + + 
Sbjct:   44 SVNQTAMADC--RAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLP--------------LAITLYVFWLLYLFLILGV-TAAKFPHGVTFLAFGNGAPDIFSALVAF--SDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTVIICTWVYQRQRS 239          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSN-SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL-INLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            P+D   W   S+  ++L +V+ P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SN  PP     FAF+GF+TS  WI     E+VN+L +LGV+F +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++  +  ++ + L+ D +   VL   + L    +L+ +P+  F+++K YG+ LL  YI F ++++
Sbjct:  311 PLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVL 573          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXX--XXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKK 740
            SV +  M  C  + + G N S+ C +V+    C  ++G+L+Y E  +C F   ++P  + +     L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLA+G++ GAG+LV T+ AG I I+ PF    RP ++DI FY++A+      L   +I    ++ +L +Y+ YV    I   +Y + + 
Sbjct:   44 SVNQTAMADC--RAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTVIICTWVYQRQRS 256          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSN-SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGI 2021
            P+D   W   S+  ++L +V+ P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SN  PP     FAF+GF+TS  WI     E+VN+L +LGV+F +  T+LGL++LA+ NS+G     IT        +    C  GP  +LL G+
Sbjct:  311 PLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGAGARRIT-------GVGAGQCP-GPQLDLLPGL 495          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXX--XXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKK 740
            SV +  M  C  + + G N S+ C +V+    C  ++G+L+Y E  +C F   ++P  + +     L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLA+G++ GAG+LV T+ AG I I+ PF    RP ++DI FY++A+      L   +I    ++ +L +Y+ YV    I   +Y + + 
Sbjct:   44 SVNQTAMADC--RAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTVIICTWVYQRQRS 256          

Query: 1725 VAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTIS-LVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF--FILIISF 2225
            + +T  + S P ++ FF  + FIT+  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+G+P+ ++T        +K ++  LV+++  L+ ++ L VL I   K+R+++  GI +L +Y VF  F ++I F
Sbjct:  437 LCVTIPNCSKPRWEKFF-MVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEF 607          

Query: 1323 ISDVQNQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTIL-PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            +SD +  R  SN +     +  D+   L F   T    L+  L P+D   W R S + K L + + P+ F+L LT+ VV+ D   + W + LNCLH V+SPL+ +  +      +    G +  +++++I   A  SV   + S+S PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++ ++    + L+ D +   VL   + L    +L+ +P+  F+++++YG  LL  Y+ F ++ +
Sbjct:  270 LSDSEEDRVSSNTN---SYDYGDEYRPLFFYQETTAQILVRALNPLDYMKWRRKSAYWKALKVFKLPVEFLLLLTVPVVDPDKDDQNWKRPLNCLHLVISPLVVVLTLQSGTYGVYEIGGLVPVWVVVVIAGTALASVTFFATSDSQPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQISRSHTEVKLEPDGLLVWVLAGALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVAL 572          

Query:  132 KNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP--TIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDR-RLDSSKCKANKNCSHDPL 869
            + + G N S+ C +++    C  D G+L+Y E  +C F   ++P    L + W L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLALG++ GAG+LV T+ AG I I+ PF    RP  +DI+FY++A+    ++L R ++    ++ +L +Y+ YV    +   +Y      Q+Q R      + VT  ++ +++  R+ S+    +    + PL
Sbjct:   54 RKVCGLNVSDRCDFIRTNPDCHSDGGYLDYLEGIFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPHTAGLALGALFGAGVLVTTVVAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVTVILCTWIY------QRQRRGSLFCPMPVTPEILSDSEEDRVSSNTNSYDYGDEYRPL 294          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSN-SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL-INLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            P+D   W   S+  ++L +V+ P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SN  PP     FAF+GF+TS  WI     E+VN+L +LGV+F +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++  +  ++ + L+ D +   VL   + L    +L+ +P+  F+++K YG+ LL  YI F ++++
Sbjct:  311 PLDYRKWRTQSISWRVLKVVKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNREPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVIFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIIRNHVVEVKLEPDGLLVWVLASALGLSLIFSLVSVPLQCFQLSKAYGLCLLLFYICFLVVVL 573          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXX--XXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKK 740
            SV +  M  C  + + G N S+ C +V+    C  ++G+L+Y E  +C F   ++P  + +     L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLA+G++ GAG+LV T+ AG I I+ PF    RP ++DI FY++A+      L   +I    ++ +L +Y+ YV    I   +Y + + 
Sbjct:   44 SVNQTAMADC--RAVCGLNTSDRCDFVRRNPDCRSEAGYLDYLEGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTNLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPRTAGLAIGALFGAGVLVTTVVAGGITILHPFMAASRPFLRDIAFYMVAVFLTFTALYLGRITLTWALGYLGLYVFYVVTVIICTWVYQRQRS 256          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPI-GTDGFIVTYXXXXXXXXXXXSVAITSKSNS-PPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPI-LINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            P+D   W   S+  K+L + + P+ F+L LT+ VV+ D   + W + LNCL  V+SPL+ +  +   +  I    G +  + +++I   A  SV   + SNS PP     FAF+GF+TS  WI     E+VN+L +LGVVF +  T+LGL++LA+ NS+GD  S+ TLA++ YPR+A++AC GG +FN+LVG+GL   ++  +     + L+ D +   VL   + L    +L+ +P+  F+++K YG+ LL  YI F ++++
Sbjct:  311 PLDYRKWRTQSISCKLLKVAKLPVEFLLLLTVPVVDPDKDDRNWKRPLNCLQLVISPLVLVLTLQSGVYGIYEIGGLLPVWAVVVIVGTALASVTFFATSNSEPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDAFSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLLQIVRSHASEVKLEPDGLLVWVLASALGLSLVFSLVSVPLQCFQLSKAYGLCLLLFYICFIVVVL 573          

Query:   96 SVPRKVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXX--XXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKK 740
             V +  M  C  + +   N S+ C +VK    C  + G+L+Y +  +C F   ++P  + +     L L L +  TA  FF P L  ++  L++S N+AGVT LA GNGA D+FS+L A   S+    GLA+G++ GAG+LV T+ AG I I+ PF    RP ++DI FY++A+      L   +I    ++ +L +Y+ YV    I   +Y + + 
Sbjct:   44 GVNQTAMADC--RAVCSLNTSDRCDFVKRNPDCHSEGGYLDYLKGIFCYFPPNLLPLAITLYVFWLLYLFLILGVTAAKFFCPNLSAISTSLKLSHNVAGVTFLAFGNGAPDIFSALVAF--SDPRTAGLAIGALFGAGVLVTTVVAGGITILRPFMAASRPFLRDITFYMVAVFLTFTALYLGRITLVWALGYLGLYVFYVVTVIICTWVYQRQRS 256          

Query: 1455 DLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMN-PIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPIL---INLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLI 2240
            + +DW  +++F K++A +      +  LTI + E       W K L  LH    P   +  I   +  P      +  Y + +  +LA + +  T  S  P  Y+  +++ GFI SI WIY I +E+VNV+  LGVV  +   +LGL+ILA++NS+GDL++++++ K+ YPR+A AA IGGPLFNLL+G GLPF+I   Q   +   IN     ++L   ISL+ T  LI +P+ KFR+ + +  +L++IYI F + +I   T ++
Sbjct:  411 EAEDWEEMNIFSKVMAYINVVPNLLFKLTIPLNE-----MSWSKPLTLLHAFTCPAFLLFSIQFFLETPFSGSPGLWVYGLAVSIVLAILIMVFTELSVQPKYYKEIYSYSGFIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFTIAKLQGKYISMTINPTYRLLILFLAISLLAT--LIGIPVQKFRLQRPHAAVLISIYIAFIVFVILSETGVL 669          

Query:  165 CQYVK-NVSACLFDSGFLNYFEWQYCGFD--SRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTI-ILLRRKIEFWSSIVFLSIYIVYVFVTAISRALY-LKLKKCQKQ 752
            C YV  N +AC    G+L + ++  C     SR++  I+ +++ LVL + V++ AD FF+P +  +   LR+S+++AGVT +A GNGA DVF S++++LSS  P   LALG + G G+ V T+    I++  PF++     I+D++FYL+AL +     +   ++  W  + FL +Y++YV     ++A++  K K  QKQ
Sbjct:   56 CDYVNCNDNACE-GGGYLLWTQYVECASSTFSRVILIIVGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGSIASVLSSPTPKADLALGELFGGGLFVTTMVVSTIILTSPFDVEVFSTIRDLLFYLVALSFLAFCFVFYNRVTLWMPLTFLGLYLLYVITVIGAQAVHNRKRKALQKQ 255          

Query: 1458 LDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHV-NMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQK---PILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILI 2216
            +D+W  +++F+K++A++ +   F+  LTI   E+      W K +  L C++ P+  +  I V +++P      +  Y +++  LL    +  T     PP Y+   ++ GF+ SI WIY I +E+VNV+  LGVV  +   +LGL+ILA++NS+GDL++++++AK+ YPR+A AA IGG LFNLL+G GLPF+I   Q     ++IN     ++L   ISL+ T  LI +   K+ + +I+   L+ IYI FF+ I
Sbjct:  330 MDEWDEMNIFQKVIAVLNTIPNFLFKLTIPHSEQP-----WSKPITLLQCLICPVFLLFCIQVCSISPFPNSPGLWMYGLILSVLLTAAVLFFTELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTIAKIQGKSISMIINPTYRLLMLFLAISLIFT--LIAMFAQKYFLRRIHSYSLVFIYISFFVFI 579          

Query:  114 MESCNPKN------ITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDS--RIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILL-RRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENI 773
            +E C P +        G N +  C+YVK         G++ +  +  C      RI+  I  +++ LVL + V++ AD FF+P +  +   LR+S+++AGVT +A GNGA DVF +++++LSS  P   LALG + GAG+ V T+   + +   PF+      I+DI FYL+AL +     +    +E W  I FL +Y++YV    +S+ L+ + KK +++   ++ +
Sbjct:   42 IEKCIPDDGEQCTIQAGWNSTQVCEYVKCNDDNCEGGGYVLWTRYVECASSPAVRIILIITGVIYMLVLFIMVSSAADDFFSPSISSIVAHLRISESVAGVTFMAFGNGAPDVFGAIASVLSSPTPKADLALGELFGAGLFVTTMVLAVTIFTRPFKAEVFSSIRDIAFYLVALAFLAFCFVYYDHVEIWMPITFLGVYLIYVCTVILSQILHNRHKKDEEKVDEVKTV 270          

Query:  114 MESCNPKNITGTNYSNE--CQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNR---KLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKL--KIRFYSAD---------TNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLT----FPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQ-KPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            MESCNPKN T     NE  C YV N  +C FDSGF+NYF+WQ+CGFD+RI+PTILM LWFLVLLL+VA TADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSA++S+++PNV LALGSILGAGILVNT+TAGIIMII PF++MRRPIIKD+IFYL+ALLWC  IL+RR+IE WSS+VFL IY++YV VT +SRA+Y+K K+                              K    ++  H    +G  N  Y  EN      V   N LN     L +P     ++    R   +  S  P+  S    R+ S  +R+MGS AKIII+NE+ +EI++    +   +        LS       PK   + RF S D         T    R+I+EF++ A     K +I   +NQ  +S++   L ++   D    T    FPG FKHFL+ I+P++ ++W   S+F K+L+++QSPIMFILTLTI VVEE+ +LKGWCK+LNCLHC+LSPLIWITFI  +  P+G+ GFI+ +L+LIIG+ A IS AITSK+N+PP Y   FAF+GF+TSIFWIY I NEIVN+L T GVV SIPQTILGL+ILAFANS+GDLVSNI LA++ +PRIAYAACIGGPLFNLLVGIGLPFSI  A+   I + LKS+T+VL+ TI L+T MNLI LP+++FR+  +YGII++ IY++F + ++ FATN+I VT+
Sbjct:    1 MESCNPKNKT----FNESFCNYVINRGSCSFDSGFINYFQWQFCGFDNRIIPTILMFLWFLVLLLAVAVTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAVISTSSPNVSLALGSILGAGILVNTVTAGIIMIIVPFDVMRRPIIKDLIFYLLALLWCMFILIRRQIELWSSVVFLIIYVIYVTVTGVSRAIYVKQKR-----------------------------GKLTTQEDTQHKKDESGS-NIQYSRENRAYINDVEPCNSLNSLPSSLQSPNSLTNSNQDSER---NHLSLIPM-QSFRSKRIPSIRNRTMGSIAKIIIENEYHKEILEAKKNMNRKRS-------LSLDLATEKPKFNNRKRFISLDQENLKEIKKTEKENRKIKEFQSPA----PKINIISEENQIEKSSVDSTLHTSSESDIDVETKDVQFPGLFKHFLMKIIPINFEEWKEQSLFSKVLSVIQSPIMFILTLTIPVVEEEEYLKGWCKLLNCLHCILSPLIWITFIKFSAVPLGSQGFILIHLVLIIGVCAAISAAITSKANAPPEYYSLFAFVGFLTSIFWIYAIANEIVNILETFGVVLSIPQTILGLTILAFANSIGDLVSNIMLARKKFPRIAYAACIGGPLFNLLVGIGLPFSIANARYGKIKVELKSETIVLISTILLITIMNLIYLPVMRFRLRPVYGIIMIVIYVLFLLFVLLFATNVIKVTL 685          

Query:  942 QLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFK-NIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            QL R  N  T  +E    ++    + CS K    S   +  RS SHRS+ S AKIII NEHE+E M+ +   K +      S  L+ LN+ ++ K  IR++S       R I++ K +I  E    +    V  +    N   I ++  N DS  +TFPG +KHF LTILPVDL++W   S F K L+I+QSP MFILTLTI +V+E  +LKGWCKILNC+HC+LS + W+   +V   P GT  F++ YL +I+G + G+ VA TSK + PPIYQPFFAF+G ITSI WIYEI NEIVN+L   GVVF+I   ILGLS+LAFANS GDLVSN+TLAK NYPRI Y+AC+GGPLFNLLVGIG+PFSI+T   PI + L   ++VL+FTI LVT +NL+ LP++KF+  + YGIIL+TIY+++F+L+I FA ++I VT+
Sbjct:  427 QLERFYN--TLPSERPSTEVNHLKYSCSIKQKNLSPRSSIERSASHRSIRSMAKIIIDNEHEKERMENHPTAKKANLIKSLS--LTVLNEYAL-KSNIRYWSM------REIQKAKSDITNEWDILEGNYKVHPENENENKFNI-ETGENGDS-VVTFPGPWKHFALTILPVDLEEWREQSGFSKFLSIIQSPFMFILTLTIPIVDETAYLKGWCKILNCIHCLLSLVFWVLLPNVYNTPFGTSNFLLVYLFIILGFIVGVVVAFTSKVDKPPIYQPFFAFIGLITSILWIYEIANEIVNILSVFGVVFNISSVILGLSVLAFANSTGDLVSNVTLAKNNYPRIGYSACVGGPLFNLLVGIGIPFSIRTFSGPIPVQLTGTSIVLIFTIMLVTALNLLCLPLMKFQPKRFYGIILITIYVIYFVLVILFAVDIIKVTL 851          

Query:  114 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVT 788
            M +C P   +  NYSN C Y+ N   C  +SG +NY++WQYC F +R  P ILM LWFL LL  + T+ADSF APCLVVV K +RMS+NLAGVTLLALGNGAADVFSSLSA+ S++NPNVGLA G+ILGAG+ VN ITAGIIMI+ PF+IM+RPI+KD++FY +AL+WC II ++++IE WSS+VFL+IY++Y+ VT ISR LY++ +K  K      NI +++T
Sbjct:    1 MAACTPLKFSSFNYSNACDYITNFKGCSPNSGLINYYQWQYCAFGNRWAPGILMFLWFLFLLTGITTSADSFLAPCLVVVAKTMRMSENLAGVTLLALGNGAADVFSSLSAVTSNSNPNVGLAFGAILGAGVFVNAITAGIIMILSPFKIMKRPILKDLLFYFVALIWCMIIFIKKQIELWSSLVFLAIYVIYILVTVISRLLYVRNEKSNKTIIQTNNISITIT 225          

Query:  732 LKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQ------------RTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            +K+C   E  ++++ V  TN   +    RL +S+     +C H+   N +       +   ++L   Q+ +      N   S  +S++      H  S K  + S   +  RS+SHRS+GS A+III  EHE+E M+K+   K        S  L+ +N+  + K KIRF S   N                  +KS SD+ N+              E+     L++  N DS  +TFPG +KHF LTILPVDL++W   S F K L+I+QSP MFILTLTI +V+E  +LKGWCKILNC+HC+LS + W+   +V   P GT  F++ YL +I+G + G+ VA TSK + PPIYQPFFAF+G ITSI WIYEI NEIVN+L   GVVF+I   ILGLS+LAFANS GDLVSN+TLAK NYPRI Y+AC+GGPLFNLLVGIG+PFSI+T   PI + L   ++VL+FTI LVTT+NL+ LP++KF+  + YGIIL+ IYI++F+L+I FA ++I VT+
Sbjct:  411 IKECY--EDKLDHLNVPQTN---YQGKSRLVTSQ----HSCPHESECNAK-------KRVYDYLNSYQFERSYNSFENALPSLRSSIIGNHQK-HSYSIKRKHHSARNSMTRSSSHRSIGSLAQIIIDKEHEKERMEKHPTSKKITHFRSIS--LTIINESPL-KTKIRFRSMSEN------------------EKSKSDITNEWGIIKGNHKIPPENENENKFNLETGENGDS-VVTFPGPWKHFALTILPVDLEEWREQSGFSKFLSIIQSPFMFILTLTIPIVDETAYLKGWCKILNCIHCLLSLVFWVLLPNVYNTPFGTSNFLLVYLFIILGFIVGVVVAFTSKVDKPPIYQPFFAFIGLITSILWIYEIANEIVNILSVFGVVFNISSVILGLSVLAFANSTGDLVSNVTLAKNNYPRIGYSACVGGPLFNLLVGIGIPFSIRTFSGPIPVQLTGTSIVLIFTIMLVTTLNLLCLPLMKFQPKRFYGIILIIIYIIYFVLVILFAVDIIKVTL 890          

Query:  114 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENI-------EVSVTNTVIFNNDRRLDSS----------KCKANKNCSHDPLNNGQINASYLNENAGE 917
            M+ C P N + +NYSN CQY+   S+C+ + GF+NYF+WQYC FD+R  PTILM+LWFL LL  +AT ADSF APCLVVV K +RMS+NLAGVTLLALGNGAADVFSSLSA+ S++NPNVGLA G ILGAGI VN+ITAGIIMII PF++M+RPIIKD +FY  AL+WC  I +RR+IE WSS+VFL +Y +Y+ VT ISR LY++  K +       N        +++V N  I   D R  S+          + KAN+N +   +NN +I  +  N+   +
Sbjct:    1 MDLCTPLNFSSSNYSNICQYITFFSSCIPNLGFINYFQWQYCSFDNRWAPTILMLLWFLFLLTGIATAADSFLAPCLVVVAKTMRMSENLAGVTLLALGNGAADVFSSLSAVTSTSNPNVGLAFGGILGAGIFVNSITAGIIMIITPFKLMKRPIIKDFLFYFSALIWCMFIFIRRQIELWSSLVFLILYAIYILVTVISRLLYVRHIKSKATTIKTNNSNITIRTPDLNVENAEIQQKDNRDSSTSNSVLIFKDNRSKANQNIT---VNNIEITVTASNDEDDQ 282          

Query:  108 KVMESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDS-RIVPT-IXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSF-----HRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTM--NLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            ++ E C  +++   N S +C +V+    C  D  F+ Y  + YC F S    P  +++ +  L++ + +  TAD F AP L+V++  LR+SQN+AG+T LA GNGA D+ SSL+ I  +  P++ +      G    V  + AG I +   F+IM RP ++DIIFY+ A  W   I   +KI  + SI F+ +YI+++ V  +SR +Y ++K+                       +    + + K +++ +H    + Q+N     +  G +L  P     ++         E  V+  R SF     HR +R+P      +T V   +HR    F  +I  +E ER                             + +++ R   A +  + R      ++  +      I   Q   + S L  I  S    ++  L+     K   L ++P+DL+DWP  + + K   + ++PI FILTLT  VV+ +     WC++LNCLHCV+ P+  +    V  + +   GF V  ++++      ++V  TSK   PP Y   FA++GF  ++FWIY + NE+V++L  +G+V  +    LG+++LA+ NS+GD +SN+ +AK+ YPR+A +AC GGPL NLL+G G+P+++K  Q    +NLK   ++ V   ++  T+   L+V+ IL+F V + +G  LL +Y +F  + I
Sbjct:    6 ELAEVC--EHVHHFNVSEQCNFVRGCDQCQSDEQFIPYMTFVYCAFGSGNTAPALVVLTIALLIMFVGLGITADDFLAPALIVISDTLRLSQNIAGITFLAFGNGAPDIISSLAGIQQAR-PDLVIGELFGAGIY--VTCVVAGSICLTQDFKIMERPFLRDIIFYIGATYWAFFIFYTQKITLYHSIGFIILYIIFIIVVLMSRIVYQRMKE-----------------------NELAKAEEAKRSQSATHISAFHQQMNGPPDIDQTGNYLAPPIPPLFSKATYEEPEPEEMGVILRRFSFRESISHR-TRRP-----TITGVHLHNHRRNSIF--MITASEQER-----------------------------MAQIRSR---ASSKASTRS----GSVCTQSGIPPVILSPQATSSLSALVSIATSVEELEAPRLS---PLKELALHLMPIDLNDWPEKTWYGKFYEVCKAPIYFILTLTTPVVDYENDKNNWCRLLNCLHCVIGPVFILLVTGVVDSTVA--GFPVAVIVVLGATAVALTVFFTSKYEEPPRYHWAFAYLGFFVAVFWIYGLANEVVSLLKAVGIVIGLSDAFLGMTVLAWGNSIGDFISNLAVAKQGYPRMAISACYGGPLLNLLLGFGIPYTLKLVQIGGTLNLKWSKMIGVLYGTMCQTLVSTLVVMTILQFTVRRAFGAYLLAVYAIFLTVAI 641          

Query:  150 NYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPT--IXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDI---RTSF-----HRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIA--VEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTM--NLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            N S +C +V+    C  D  F+ Y  + YC F S   P   + +++  L + + +  TAD F AP L+V++  LR+SQN+AG+T LA GNGA D+ SSL+ I     P++ +      G    V  + AG I +   F+IM RP ++DIIFY+ A  W   I   +K+  + SI F+ +YI+++     SR +Y  +K     E+ +   E           + +L  SKC    +  H  +N  Q          G +L  P       K  +     E   + I   R SF     HR +R+P      +T V   +HR    F  +I  +E ER    ++     +          S  N   +P + +      +  AA  +    +IA  VE L+   +S +                              +   L +LP+DL++WP    + K+  + ++PI F+LTLT  VV+ +     WC++LN LHCV+SP+ +I  +   +N I   GF +  ++ ++     + V  TSK + PP Y   FA++GF  ++FWIY + NE+V++L T+G+V  +    LG+++LA+ NS+GD +SN+ +A++ YPR+A +AC GGPL NLL+G G+P+++K  Q   ++ L+   ++ V   ++  T+   L+V+ IL+F V + +G  LL +Y  +  + I
Sbjct:    8 NSSEQCAFVRGCQQCQEDEQFIPYMTFVYCAFGSGNTPPALVCLVIALLTMFVGLGITADDFLAPALIVISDTLRLSQNIAGITFLAFGNGAPDIISSLAGI-QQARPDLVIGELFGAGIY--VVCVVAGSICLTQDFKIMERPFLRDIIFYIGATYWAFYIFYTQKMTLYHSIGFIILYIMFIAFVVTSRVVYQHMK-----EKELAKAE-----------EAKL--SKCSQQISTIHQQMNGDQ---------TGNYLAPPPVPLTFSKAAHEEPEPEPEDMGIMLRRFSFRESISHR-TRRP-----TVTGVHLHNHRRNSIF--MITASEQERMAQIRSRASSKASSRRD-----SVSNQNGMPAVML------SPQAASSLSALVSIAASVEDLEAPQLSPL------------------------------RELGLHLLPIDLNEWPEKKWYGKLYEVCKAPIYFVLTLTTPVVDYENDKNNWCRLLNSLHCVISPM-FILLVTQVVN-ITVAGFPIAVIVFLVAACLALVVFFTSKYDEPPKYHWIFAYLGFFVAVFWIYGLANEVVSLLKTVGIVIGLSDAFLGMTVLAWGNSIGDFISNLAVARQGYPRMAISACYGGPLLNLLLGFGIPYTLKLVQTGGVLRLRWSNMIAVLYGTICQTLVSTLVVMTILRFTVRRAFGAYLLVVYATYLTVAI 630          

Query: 1329 DVQ-NQRTESNLSRILQSNRNDDSSFLTF-PGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWI-TFI--HVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTV---VLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            D+Q +     N++  LQ +  +    ++F   T K FL +I PVD   W R     + L I+Q P   +L LT+ VV+ D     W + LNCLH +  PL+ + TF   H  +  I  D F V  L  +IG+     V  T+ +  PP Y   F+ +GF+ S  WI  + +EIV+VL  LG+V S+  T+LGL++LA+ NS+GD  S+IT+A++ YPR+A +AC GG +FN+L G+GL   ++     +++ L+ + +   VL   + L   ++ +++P+ +F +N+ YGI LL  Y  F ++ +
Sbjct:  279 DIQASDYYRENINGTLQEHEAEYEPLISFTETTSKIFLKSISPVDTRIWRRSHWAWRALKIIQLPFEVVLLLTVPVVDTDKEDHNWKRPLNCLHIITGPLVCVLTFQSGHYGLYLIQGD-FPVWLLTALIGVFLSGIVFCTTNNERPPPYHFLFSLLGFVVSALWISTVASEIVSVLHLLGIVLSLSNTVLGLTLLAWGNSIGDCFSDITIARQGYPRMAISACFGGIIFNMLFGVGLGCLLQMFHNGVVM-LEPEGLLGWVLSGALGLSLVLSFVLVPLQRFHLNRAYGIFLLIFYAAFLVVAL 581          

Query:  156 SNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPT--IXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPL 869
            ++ C++V N   C  + GF+NY +  +C     ++P    L I+W LV+ L +   A  FF P L  ++  LR++ N+AGVT LALGNGA DVFS+++A   S     GLA+G++ GAGI V T+ AG + ++ PF +  RP ++DIIFY+ A+ W   IL +  I+   ++ +L +Y++YV    +S   Y+  ++ +    P++N EV+  N +  ++  R + +         ++PL
Sbjct:   71 ADRCEFVLNTPDCAAEGGFINYPKITFCLLAPNLLPLAIFLYIVWLLVMFLVLGLIASQFFCPNLSAISSTLRLTHNVAGVTFLALGNGAPDVFSAMAAF--SRPQTAGLAIGALFGAGIFVTTVVAGSVTLVKPFTVASRPFLRDIIFYMAAVFWTFTILYKGWIDLKEALGYLGLYVLYVITVVVST--YIYRRRTRSLRGPLQNSEVA--NDIQASDYYRENINGTLQEHEAEYEPL 304          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASY----------LNENAGEFLKVPQYNQLNRK 956
            ++A   D FF P L V+T+ L +S ++AG T +A G  A ++F+S+  +  S++ NVG+          ++  I    +       +   P+ +D+ FY++ L+   +  L   I +W SI  L+ Y  YV     +  + + +K    + + +E +E     + +  +D    S+K +  +  S   L+N  +  S           L+E  G + K+  Y+ +  +
Sbjct:  120 ALAIVCDEFFVPALTVITEKLAISDDVAGATFMAAGGSAPELFTSVIGVFISHS-NVGIGTIVGSAVFNILFVIGMCAVFSKEILNLTWWPLFRDVSFYILGLIMLIVFFLDNYISYWESIALLTAYACYVIFMKYNGQVEMFIKGLINRNQVVEVVEAPPKVSPVAVDDESKVSAKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLSEELGTYGKLKYYHSMTEE 346          

Query: 1755 PIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP---FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLI 2240
            P  + FF  + F+ +I WI      +V     +G    I + I+GL++LA   S+ DL++++ +A++    +A ++ +G  +F++ VG+  P   +S+    KPI+++  +     +  + L+    +I +   K++++K+ G I+  +Y+VF ++ +     +I
Sbjct:  446 PTSKKFFP-ITFLGAICWIAAFSYLMVWWAHQVGETIGITEEIMGLTMLAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLLYSLINGLKPIVVS-SNGLFCAIVLLFLMLLFVIISIAACKWKMSKLLGFIMFLLYLVFLVVSVMLEDKII 608          

Query: 1755 PIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTA--QKPILINLKSDTVVLVFTISLVTT-MNLIVLPILKFRVNKIYGIILLTIYIVF--FILIISF 2225
            P ++ +F F  FI+S  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+GLP++++T       +I+L S  +++   + L +  + ++ + + K+ ++K  GI+ L +Y VF  F ++I F
Sbjct:  462 PRWERWFMFT-FISSTLWIAGFSYIMVWMVTVIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNSIGSNVFDILVGLGLPWALQTLAIDYGSVIHLNSRGLIISVGLLLASVFLTVLGVHLNKWTLDKRLGILCLLMYAVFLCFSILIEF 622          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNP----NVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTN 791
            ++A   D +F P L  + + L +S+++AG T +A G+ A ++F+S+  +  +        +  +    +   I V  I AG  + +  + +MR     D  +Y I++    + +   K+ +W S+V + +Y+VY+ +   +  +   L++ +K    + N   S T+
Sbjct:  115 ALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFAGQAVRLSCWTLMR-----DSTYYTISVTTLIVFIYDEKVTWWESLVLILMYLVYILIMKCNSRVVHYLERRKKNSTNLGNGTASNTD 276          

Query: 1755 PIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTA--QKPILINLKSDTVVLVFTISLVTT-MNLIVLPILKFRVNKIYGIILLTIYIVF--FILIISF 2225
            P ++ +F F  FI+S  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+GLP++++T       +I+L S  +++   + L +  + ++ + + K+ ++K  GI+ L +Y VF  F ++I F
Sbjct:  424 PRWERWFMFT-FISSTLWIAGFSYIMVWMVTVIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNSIGSNVFDILVGLGLPWALQTLAIDYGSVIHLNSRGLIISVGLLLASVFLTVLGVHLNKWTLDKRLGILCLLMYAVFLCFSILIEF 584          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNP----NVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTN 791
            ++A   D +F P L  + + L +S+++AG T +A G+ A ++F+S+  +  +        +  +    +   I V  I AG  + +  + +MR     D  +Y I++    + +   K+ +W S+V + +Y+VY+ +   +  +   L++ +K    + N   S T+
Sbjct:   77 ALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFAGQAVRLSCWTLMR-----DSTYYTISVTTLIVFIYDEKVTWWESLVLILMYLVYILIMKCNSRVVHYLERRKKNSTNLGNGTASNTD 238          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNN 875
            ++A   D FF P L V+T+ L +S ++AG T +A G  A ++F+S+  +  S++ NVG+          ++  I    +       +   P+ +D+ FY++ L+   +  L   I +W SI  L+ Y  YV     +  + + +K    + + +E +E     + +  +D    S+K +  +  S   L+N
Sbjct:  120 ALAIVCDEFFVPALTVITEKLAISDDVAGATFMAAGGSAPELFTSVIGVFISHS-NVGIGTIVGSAVFNILFVIGMCAVFSKEILNLTWWPLFRDVSFYILGLIMLIVFFLDNYISYWESIALLTAYACYVIFMKYNGQVEMFIKGLINRNQVVEVVEAPPKVSPVAVDDESKVSAKPRLQRGGSSASLHN 309          

Query: 1755 PIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP---FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLI 2240
            P  + FF  + F+ +I WI      +V     +G    I + I+GL++LA   S+ DL++++ +A++    +A ++ +G  +F++ VG+  P   +S+    KPI+++  +     +  + L+    +I +   K++++K+ G I+  +Y+VF ++ +     +I
Sbjct:  451 PTSKKFFP-ITFLGAICWIAAFSYLMVWWAHQVGETIGITEEIMGLTMLAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLLYSLINGLKPIVVS-SNGLFCAIVLLFLMLLFVIISIAACKWKMSKLLGFIMFLLYLVFLVVSVMLEDKII 613          

Query: 1416 GTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTI---SVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVN---MNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGL-------PFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFF 2207
            G    FLL++ P+D  +W R     ++L +V  P+  +L LT+   +V+ ED   + W + LNCL  +  PL  +  ++     M P+G  G +  + +++        VA  + S  PP +Q  FA +GF+ S  W+  I NE+VN+L T GVVF I  T+LGL++LA+ NSV D V++IT+A++ YPR+A +AC GG +FN+LVGIGL       P  ++ AQ   L+       VL  ++ +   ++ + LP+  F + + YG+ L  +Y+ F 
Sbjct:   82 GKLYRFLLSLSPLDPAEWRRRGYIWRLLKVVVLPVELLLILTVPVMNVMHED---RKWNRPLNCLQLMTGPLAALYSLNGGLYFMLPVG--GTLPLWSLILAIGCLLAVVAFITTSEQPPAFQLAFAVLGFVVSALWMNAIANEVVNLLQTFGVVFGISSTVLGLTLLAWGNSVPDFVADITMARQGYPRMAISACFGGIVFNILVGIGLGCLLSMPPSHMQQAQ---LVPDVPLVWVLCASLGISLVLSFVALPLQGFYLTRKYGVCLFALYLAFL 350          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRR--------PIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYV 695
            ++A   D FF P L V+T+ L +S ++AG T +A G  A ++F+SL  +  S++ NV        G G +V +    I+ +I    +  R        P+ +D+ FY++ L    I  L   I++W S++ LS Y+ YV
Sbjct:   47 ALAIVCDEFFVPALGVITEKLAISDDVAGATFMAAGGSAPELFTSLIGVFISHS-NV--------GIGTIVGSAVFNILFVIGMCAVFSREILVLTWWPLFRDVSFYIVGLSMLIIFFLDNLIQWWESMLLLSCYVSYV 176          

Query: 1773 FAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP---FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            F  + F  SI WI      +V     +G    I + I+GL+ILA   S+ DL++++ +A++    +A ++ +G  +F++ VG+ +P   FS+     P+ ++  +     +  + L+    ++ +   ++ +NK+ G  +  +Y VF I+ +   T  ++  +
Sbjct:  391 FFMVTFFGSILWIAIFSYLMVWWAHQVGETIGITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPMPWLMFSLVKGFAPVQVS-SNGLFCAIVLLFLMLLFVILTIAACRWHMNKLLGFCMFLLYFVFLIISVMLETRTLHCPV 552          

Query: 1788 FITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTIS-LVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF--FILIISF 2225
            F+ S  WI      +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+GLP++++T       +++ ++  L++++  L+ ++ + VL I    +++++  G+  L +Y VF  F ++I F
Sbjct:  383 FVISTIWIAVFSYVMVWMVTVIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILVGLGLPWALQTLLVDYGSHVEINSRGLIYSVVLLLASVGITVLGIYLNNWKLDRKLGLACLFVYAVFLCFSIMIEF 533          

Query: 1728 AITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP-FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLI---------------VLPILKFRVNKIYGIILLTIYIV 2201
             I +K NS  I+      + F+ S+  + + V+ IV  L     VF+I +TILGL+I  + NS+GDLVSNIT  K     IA  AC G PL   L G+G     I    K   I    D+ +L+  I      NLI               ++P+  ++++K   I LLT+YIV
Sbjct:  581 TIPNKFNSDIIFT-----VAFLLSLACLSKAVHIIVVTLTHWINVFNISETILGLTIFTWGNSIGDLVSNITFVKIGVLEIAIGACFGSPLLYFLFGVGFDGIMIMLGDKTGKIVSGRDSNILMHHIDFKVDKNLINTGVGILIAFLIFTVLIPLNDWKIDKKISIALLTLYIV 749          

Query: 1818 IVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAY---------------AACIGGPLFNLLVGIG 2024
            + N ++ ++     +  + + ILGL+I A+ NSVGDL+SNI++ +    +  Y               A+C+GG + N + GIG
Sbjct:  545 LANSLIEMMEIYQKILGLSKAILGLTIFAWGNSVGDLISNISMCRLYKTQTHYQDRVRLATKFFMISCASCLGGVMLNSMGGIG 628          

Query: 1443 ILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGT------DGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLV 2015
            +LP    D+    +F K+  I+++P   +L +TI V++ D   + W K LN LH +  P+  +         +G         ++V Y       +   S            +   F ++ FI S+ WIY   NEIVN+L + G+V  +   ILGL+ LA+ NS+GDLV++ T+A++ +P +A  AC GGP+ ++L+
Sbjct:  236 VLPFTSADFELSGIFNKVFLILKAPAAVVLNVTIPVIDYDEPYQNWNKWLNVLHLITGPMFCVLATRAAKVSLGRLYKPPRCHWVVLYKPPRCHWVGFTSRQGFCSQIHKNCFLQMFGYLAFIVSVVWIYVTANEIVNILQSFGIVLGLSNAILGLTFLAWGNSIGDLVADTTMARQGFPNMATGACFGGPMLSILL 432          

Query:  165 CQYVKNVSACLFDSGFLNYFEWQYCGFDSRI-VPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILS-SNNPNVXXXXXXXXXXXXXVNTITAGII--------MIICP--FEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQ 752
            C +V+  S C    GF+ Y  + YC     I +  +++ +  L L + +  TAD +F P L V++K LR+SQN+AGVT LA GNGA D+FS+++A+ + S NPN                 + AGI         + +C   F +  RP  +D++FYL A+ W  I + R++I    +I F+  Y  YV V  + R +  + K+ Q++
Sbjct:    1 CAFVQANSDCDLSDGFIQYIHFIYCKLPKAIPLALVILFVLMLFLFIVLGITADDYFCPSLTVISKTLRLSQNVAGVTFLAYGNGAPDIFSAIAAVSAHSKNPNAA--------------QLGAGIFVTTVVVGSVTLCTGGFHLNNRPFTRDVLFYLGAVSWMFITMYRQRITMLEAIGFIIFYFAYVVVVIVGRYVNQRWKRRQEE 194          

Query: 1788 FITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF 2204
            F+ SIFWI      +V     +G  F IP  ++GL+ LA   SV DL++++ +A++ +  +A ++ IG  LF++ VG+ LP+   +A    L    S   +L   I L   +  +V+ I   ++R++K  G  +   YI+F
Sbjct:  491 FLMSIFWIAFFSYFMVWWATEVGYTFDIPTEVMGLTFLAAGTSVPDLITSVLVARKGFGDMAVSSSIGSNLFDITVGLPLPWLCYSAVNLGLAVNVSSRGILYSVIMLFCMLIAVVVSIAASRWRMSKSLGACMFVFYIIF 631          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRK-IEFWSSIVFLSIYIVYV 695
            ++A   D FF P L V+ + L + +++AG T +A G  A ++F+S          NVG+          ++  I    +      E+   P+ +D IFY +AL+   I  L    I +W S+V L  Y  YV
Sbjct:  121 ALAIACDEFFVPSLTVIIEKLELKEDVAGATFMAAGGSAPELFTSFIGTFIDPKSNVGIGTIVGSAVFNVLFVIGMCAMFSKGVLELTWWPLFRDCIFYSLALIILIIFFLSGDVIVWWESLVLLLCYFAYV 252          

Query: 1782 MGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTA----QKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVF 2204
            + FI  I WI      +V ++  +G  F IP +++GLS++AF +SV D +S++ +A++    +A +  +G  +F++L+ +G+P+ IKT        ++IN     +   F +  +  + LI++   K+ +NK  G I L  Y +F
Sbjct:  323 LSFIICIVWIGVTSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVGSNVFDILLCLGIPWLIKTTVWEYDSSVVINSHGLFISCFFILGSI-AVTLIIIWYYKWTLNKKVGCIYLVFYFIF 466          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNP----NVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLN--NGQINASYLNENAG 914
            +VA   D +F PCL ++   L +  ++AG T +ALG+ A ++F+S+  +  +        +  +    +   I V  + AG ++ +  +     P+++D +FYL +L+   ++L+   + +  +   +S Y VY+ +   +  +   L +  K   P                + + D  + KA K   +DP+   + ++ A  L+   G
Sbjct:   38 AVAIVCDDYFVPCLEIICDRLGLQTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTVLYLAWW-----PMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMYFNPRIEAYLYRVTKTTTP----------------EYKSDLHEQKATKT-KYDPVQQTDNEVEAEILDNVNG 225          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIE--NIEVSVTNTVI 800
            ++A   D FF P L  +++ L +S+++AG T +A G+ A ++F+S++ +   ++  VG  +GS +   +++  +TA     +   ++  RP+++D + Y +++ +  I     K E + + V L +YI Y+ V   +  L   L +   Q +P E  N+ VS  ++++
Sbjct:   16 ALAIVCDDFFVPSLEAISEKLDLSEDVAGATFMAAGSSAPELFTSIAGVTVDSDVGVGTIVGSAIFNLLVIIALTAAFSGQV--LQLDWRPLLRDSVAYSLSIAFFIIFSWDGKFEMYEAAVLLILYIAYIVVMKFNPKLMDLLAEVGPQGQPTEVTNLGVSDADSLV 181          

Query: 1788 FITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIK---TAQKPILINLKSDTVVLVFTISLVTTMNL--------------IVLPILKFRVNKIYGIILLTIYIVF 2204
            F  SI WI  +   +V V+G  G + ++ +  +GL I+A   SV D +S+I +A+  +  +A +  IG  +F++ +G+GLPF I+      +PI +   ++ ++L  T  +V + ++               ++   KF++NK  G+  + +Y++F
Sbjct:  361 FTMSIVWIAILSFGLVTVVGRSGCILNVDKFTMGLVIIAIGTSVPDALSSIIVARDGFGDMAVSNAIGSNVFDINLGLGLPFVIRILIDKMEPIRMLTPAEEIMLE-TGEIVISPHVKFGFLLLLFLVIALFLMAAFKFKLNKRLGLSFVFMYVLF 515          

Query: 1788 FITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIK-TAQKPILINLKSDTVVLVFTISLVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVFF 2207
            F  SI W+  +   +V  +  +G  FSIP+ I+GL++LA  +SV D++S++ +AK     +A A CIG  +F++L  +GLP+ +  TA  P  + L     ++  ++ L  T+  IV  I    +R+++  G+IL   Y  F 
Sbjct:  453 FALSIIWMAALSYVLVWTVSIIGETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDVLC-LGLPWLLATTAVHPNSVVLIHSGHIVYVSMCLFGTVLTIVSAIHLNGWRLDRRLGVILFIAYAFFL 594          

Query: 1236 RFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNM--NPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSD---TVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            R Y   +N  A  I+EF +         +++    Q+   +  R L       S  L         L ++ PVD   W R S   ++L ++++P+  +L L + VV+ D   K W + LNCLH V++P++ +         N +  + F +  LIL++G      V  T+ ++ PP Y   FA +GF+ S   I    +E+V++L  LGVV S+  T+LGL++LA+ NS+GD  S+IT+A++ YPR+A +AC GG +FN+++G+GL   ++  +    +  +S+   T +L  ++ L   ++ I++P+ +F + + YGI LL  Y++F I+ +
Sbjct:  199 RNYVNTSNQNAPHIQEFPSSDSSDDDLPNLTGGNIQQDYESEYRPLLPYSEPTSRIL---------LSSLNPVDSRKWRRKSWRWRVLKVLKTPLEVLLLLCVPVVDPDKEDKNWRRPLNCLHLVIAPVVCVLAFQSGKYGNYMIQEQFPLWVLILLLGFFLAAIVFCTTTNDHPPKYHAVFALLGFVVSAVLISAAASEVVSLLHMLGVVLSLSNTVLGLTLLAWGNSIGDCFSDITIAQQGYPRMAISACFGGIIFNMVIGVGLGCLVQMVKTNSDVQFESEGLLTWILAGSLGLSLVLSFIIVPLSQFHLGRTYGIFLLAFYVIFLIIAL 522          

Query:  156 SNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP-TIXXXXXXXXXXXSV-ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLK 737
            +  C +VKN   C  + GF+NY    +C     + P TI +   +L  L  +   TA  FF P L  ++  L ++ N+AGVT LALGNGA D+FS+++A   S+    GLA+G++ GAG+ V T+ AG + +  PF +  RP ++D+IFY++A+ W  ++L R       ++ +LS+Y++YV    IS  +Y + +
Sbjct:    6 AERCTFVKNTPDCDMEDGFINYLNVVFCLLPPNLTPFTITLCCMWLFFLFMILGLTASKFFCPNLSAISSSLHLTHNVAGVTFLALGNGAPDIFSAMAAF--SHPHTAGLAVGALFGAGVFVTTVVAGSVSLFKPFAVASRPFLRDVIFYMVAVFWTFLMLYRGTTTLGETLGYLSLYVLYVLTVIISTYIYKRQR 199          

Query: 1449 PVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNM--NPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSD---TVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILII 2219
            PVD   W R S   ++L ++++P+  +L L + VV+ D   K W + LNCLH V++P++ +         N +  + F +  LIL++G      V  T+ ++ PP Y   FA +GF+ S   I    +E+V++L  LGVV S+  T+LGL++LA+ NS+GD  S+IT+A++ YPR+A +AC GG +FN+++G+GL   ++  +    +  +S+   T +L  ++ L   ++ I++P+ +F + + YGI LL  Y++F I+ +
Sbjct:  231 PVDSRKWRRKSWRWRVLKVLKTPLEVLLLLCVPVVDPDKEDKNWRRPLNCLHLVIAPVVCVLAFQSGKYGNYMIQEQFPLWVLILLLGFFLAAIVFCTTTNDHPPKYHAVFALLGFVVSAVLISAAASEVVSLLHMLGVVLSLSNTVLGLTLLAWGNSIGDCFSDITIAQQGYPRMAISACFGGIIFNMVIGVGLGCLVQMVKTNSDVQFESEGLLTWILAGSLGLSLVLSFIIVPLSQFHLGRTYGIFLLAFYVIFLIIAL 492          

Query:  156 SNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVP-TIXXXXXXXXXXXSV-ATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALY 725
            +  C +VKN   C  + GF+NY    +C     + P TI +   +L  L  +   TA  FF P L  ++  L ++ N+AGVT LALGNGA D+FS+++A   S+    GLA+G++ GAG+ V T+ AG + +  PF +  RP ++D+IFY++A+ W  ++L R       ++ +LS+Y++YV    IS  +Y
Sbjct:    6 AERCTFVKNTPDCDMEDGFINYLNVVFCLLPPNLTPFTITLCCMWLFFLFMILGLTASKFFCPNLSAISSSLHLTHNVAGVTFLALGNGAPDIFSAMAAF--SHPHTAGLAVGALFGAGVFVTTVVAGSVSLFKPFAVASRPFLRDVIFYMVAVFWTFLMLYRGTTTLGETLGYLSLYVLYVLTVIISTYIY 195          

Query: 1749 SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTIS-LVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF 2204
            S P ++  F  + F++S  WI  +   +V ++  +G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+GLP+++KT       ++K ++  L+F++  L+ ++ L VL +   K+ ++K  G+  L +Y+VF
Sbjct:  394 SSPRWEKCF-MLSFVSSTLWIAGLSYIMVWMVTVIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILVGLGLPWALKTLAINYGSDIKLNSKGLIFSVGLLLGSVFLTVLGVHLNKWTLDKRLGVCCLLLYLVF 547          

Query: 1749 SPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVV----LVFTIS-LVTTMNLIVLPIL--KFRVNKIYGIILLTIYIVF 2204
            + P ++ FF  + FI S  WI      +V ++   G    IP  I+G++ LA   SV D ++++ +A++    +A +  IG  +F++LVG+G+P++I+T    I ++  S+  +    LV+++  L+ ++ L VL I   K+R++   G+ +L +Y VF
Sbjct:  434 AKPRWERFF-MLSFILSTVWIAIFSYVMVWMVTVAGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWAIQT----ICVSYGSEVAINSRGLVYSVVLLLGSVALTVLGIHFNKWRLDFKLGVYVLVLYAVF 587          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIE-----NIEVSVTNTVI--FNNDRRLDSSKCKANKNCS-----------H--DPLNNGQI--NASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSR 1028
            ++A   D FF P L V+T+ L +S ++AG T +A G  A ++F+S+  +  S++ NVG+          ++  I    I       +   P+ +D+ FY++ L+   I  L   I  W S+  LS Y  YV     +  +   +K C  + + +E      ++ ++T+T+   F    RL      A+ + S           H  DPL+ G+    AS L++ A +  +V      + K N  +  A      I TS  R ++
Sbjct:  122 ALAIVCDEFFVPALTVITEKLNISDDVAGATFMAAGGSAPELFTSIIGVFISHS-NVGIGTIVGSAVFNILFVIGMCAIFSKEILNLTWWPLFRDVSFYILDLIMLIIFFLDNIILVWESVTLLSAYAAYVIFMKFNSKMEGFVKSCMHRNQVVEVEVQPKVKDNLTDTLTLPFQARPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLSEGKFREKASILHKIAKKKCQVED----SEKANGVSSRAGKMTSKISTSKDRVTQ 380          

Query: 1788 FITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLP---FSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLIN 2243
            F+ SI WI      +V     +G    I + I+GL+ILA   S+ DL++++ +A++    +A ++ +G  +F++ VG+  P   +S     KP+ ++  +     +  + L+    +I +   K+R++K+ G I+  +Y VF ++ +     +I 
Sbjct:  450 FLGSITWIAVFSYLMVWWAHQVGETIGITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLFWSFFNGLKPVQVS-SNGLFCAIVLLFLMLLFVIISIAACKWRMSKLLGFIMFMLYFVFLVVSVMLEDRVIT 603          

Query:  114 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNR LNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKC+KRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYLILIIGLLAGISVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI
Sbjct:    1 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRNLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKCLKRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYLILIIGLLAGISVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 713          

Query:  114 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNR LNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKC+KRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYLILIIGLLAGISVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGT           LGL +        DLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI
Sbjct:    1 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRNLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKCLKRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYLILIIGLLAGISVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGT-----------LGLEVCEI-----DLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQKPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 697          

Query:  114 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIH 1643
            MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNR LNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKC+KRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIH
Sbjct:    1 MESCNPKNITGTNYSNECQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTILMILWFLVLLLSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVGLALGSILGAGILVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLNENAGEFLKVPQYNQLNRNLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMKKNSKVKVSKKCLKRSVSLSALNDCSVPKLKIRFYSADTNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLTFPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIH 510          

Query:  114 MESCNPKNITGTNYSNE--CQYVKNVSACLFDSGFLNYFEWQYCGFDSRIVPTIXXXXXXXXXXXSVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLN--ENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKL--KIRFYSAD---------TNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLT----FPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQ-KPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            MESCNPKN T     NE  C YV N  +C FDSGF+NYF+WQ+CGFD+RI+PTILM LWFLVLLL+VA TADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSA++S+++PNV LALGSILGAGILVNT+TAGIIMII PF++MRRPIIKD+IFYL+ALLWC  IL+RR+IE WSS+VFL IY++YV VT +SRA+Y+K K+ +  ++                 D +    +  +N   S +       N +Y+N  E       +P   Q    L N  + +E          +  S  P+  S    R+ S  +R+MGS AKIII+NE+ +EI++    +   +        LS       PK   + RF S D         T    R+I+EF++ A     K +I   +NQ  +S++   L ++   D    T    FPG FKHFL+ I+P++ ++W   S+F K+L+++QSPIMFILTLTI VVEE+ +LKGWCK+LNCLHC+LSPLIWITFI  +  P+G+ GFI+ +L+LIIG+ A IS AITSK+N+PP Y   FAF+GF+TSIFWIY I NEIVN+L T GVV SIPQTILGL+ILAFANS+GDLVSNI LA++ +PRIAY+ACIGGPLFNLLVGIGLPFSI  A+   I + LKS+T+VL+ TI L+T MNLI LP+++FR+  +YGII++ IY++F + ++ FATN+I +T+
Sbjct:    1 MESCNPKNKT----FNESFCNYVINRGSCSFDSGFINYFQWQFCGFDNRIIPTILMFLWFLVLLLAVAVTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAVISTSSPNVSLALGSILGAGILVNTVTAGIIMIIVPFDVMRRPIIKDLIFYLLALLWCMFILIRRQIELWSSVVFLIIYVIYVTVTGVSRAIYVKQKRGKLTKK----------------EDTQHKKDESGSNIQYSRE-------NRAYINDVEPCNSLNSLPSSLQSPNSLTNSNQDSER---------NHLSLIPM-QSFRSKRIPSIRNRTMGSIAKIIIENEYHKEILEAKKFMNRKRS-------LSLDLATEKPKFNNRKRFISLDQENLKEIKKTEKENRKIKEFQSPA----PKINIISEENQIEKSSVDSTLHTSSESDIDVETKDVQFPGLFKHFLMKIIPINFEEWKEQSLFSKVLSVIQSPIMFILTLTIPVVEEEEYLKGWCKLLNCLHCILSPLIWITFIKFSAVPLGSQGFILIHLVLIIGVCAAISAAITSKANAPPEYYSLFAFVGFLTSIFWIYAIANEIVNILETFGVVLSIPQTILGLTILAFANSIGDLVSNIMLARKKFPRIAYSACIGGPLFNLLVGIGLPFSIANARYGKIKVELKSETIVLISTILLITIMNLIYLPVMRFRLRPVYGIIMIVIYVLFLLFVLLFATNVIKITL 685          

Query:  303 SVATTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAILSSNNPNVXXXXXXXXXXXXXVNTITAGIIMIICPFEIMRRPIIKDIIFYLIALLWCTIILLRRKIEFWSSIVFLSIYIVYVFVTAISRALYLKLKKCQKQERPIENIEVSVTNTVIFNNDRRLDSSKCKANKNCSHDPLNNGQINASYLN--ENAGEFLKVPQYNQLNRKLNNPTRSAEASVVDIRTSFHRCSRKPIYSSLNLTRVRSTSHRSMGSFAKIIIKNEHEREIMXXXXXXXXXXXXXXXXXXLSALNDCSVPKL--KIRFYSAD---------TNMAARRIEEFKNIAVEKLKKKSISDVQNQRTESNLSRILQSNRNDDSSFLT----FPGTFKHFLLTILPVDLDDWPRLSVFKKILAIVQSPIMFILTLTISVVEEDVFLKGWCKILNCLHCVLSPLIWITFIHVNMNPIGTDGFIVTYXXXXXXXXXXXSVAITSKSNSPPIYQPFFAFMGFITSIFWIYEIVNEIVNVLGTLGVVFSIPQTILGLSILAFANSVGDLVSNITLAKRNYPRIAYAACIGGPLFNLLVGIGLPFSIKTAQ-KPILINLKSDTVVLVFTISLVTTMNLIVLPILKFRVNKIYGIILLTIYIVFFILIISFATNLINVTI 2252
            +VA TADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSA++S+++PNV LALGSILGAGILVNT+TAGIIMII PF++MRRPIIKD+IFYL+ALLWC  IL+RR+IE WSS+VFL IY++YV VT +SRA+Y+K K+ +  ++                 D +    +  +N   S +       N +Y+N  E       +P   Q    L N  + +E          +  S  P+  S    R+ S  +R+MGS AKIII+NE+ +EI++    +   +        LS       PK   + RF S D         T    R+I+EF++ A     K +I   +NQ  +S++   L ++   D    T    FPG FKHFL+ I+P++ ++W   S+F K+L+++QSPIMFILTLTI VVEE+ +LKGWCK+LNCLHC+LSPLIWITFI  +  P+G+ GFI+ +L+LIIG+ A IS AITSK+N+PP Y   FAF+GF+TSIFWIY I NEIVN+L T GVV SIPQTILGL+ILAFANS+GDLVSNI LA++ +PRIAY+ACIGGPLFNLLVGIGLPFSI  A+   I + LKS+T+VL+ TI L+T MNLI LP+++FR+  +YGII++ IY++F + ++ FATN+I +T+
Sbjct:   11 AVAVTADSFFAPCLVVVTKILRMSQNLAGVTLLALGNGAADVFSSLSAVISTSSPNVSLALGSILGAGILVNTVTAGIIMIIVPFDVMRRPIIKDLIFYLLALLWCMFILIRRQIELWSSVVFLIIYVIYVTVTGVSRAIYVKQKRGKLTKK----------------EDTQHKKDESGSNIQYSRE-------NRAYINDVEPCNSLNSLPSSLQSPNSLTNSNQDSER---------NHLSLIPM-QSFRSKRIPSIRNRTMGSIAKIIIENEYHKEILEAKKFMNRKRS-------LSLDLATEKPKFNNRKRFISLDQENLKEIKKTEKENRKIKEFQSPA----PKINIISEENQIEKSSVDSTLHTSSESDIDVETKDVQFPGLFKHFLMKIIPINFEEWKEQSLFSKVLSVIQSPIMFILTLTIPVVEEEEYLKGWCKLLNCLHCILSPLIWITFIKFSAVPLGSQGFILIHLVLIIGVCAAISAAITSKANAPPEYYSLFAFVGFLTSIFWIYAIANEIVNILETFGVVLSIPQTILGLTILAFANSIGDLVSNIMLARKKFPRIAYSACIGGPLFNLLVGIGLPFSIANARYGKIKVELKSETIVLISTILLITIMNLIYLPVMRFRLRPVYGIIMIVIYVLFLLFVLLFATNVIKITL 634