NudC domain-containing 3-like

Overview
NameNudC domain-containing 3-like
Smed IDSMED30001822
Length (bp)962
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of NudC domain-containing 3-like (SMED30001822) t-SNE clustered cells

Violin plots show distribution of expression levels for NudC domain-containing 3-like (SMED30001822) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of NudC domain-containing 3-like (SMED30001822) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for NudC domain-containing 3-like (SMED30001822) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001822

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30001822SMESG000064942.1 SmedASXL_014034SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30001822SMESG000064942.1 SmedASXL_014034SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30001822SMESG000064942.1 dd_Smed_v4_7023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001822SMESG000064942.1 dd_Smed_v4_7023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001822SMESG000064942.1 dd_Smed_v4_7023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30001822SMESG000064942.1 dd_Smed_v4_7023_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Human
Match: NUDCD3 (NudC domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22208])

HSP 1 Score: 167.933 bits (424), Expect = 9.638e-49
Identity = 104/349 (29.80%), Postives = 173/349 (49.57%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAF------------KKHKDIFESSLSNNCRAEKSILNQSQESDK-----KEIQIYRTVSND-NSKISKLE-----NDLIY----------VADA---------------------ESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            M+    E +D  LL I+Q V  + +FL +LFGFL R+TD Y ++     ++GF PG A+ L+L  F            K+ +++ E          K++   + E +      +EI+I  T   D + ++ K++      ++ +          VA A                     +SYNGA+ ENYTWSQ   +L++RV +P+ V   K ++V +    I V    +N  + +++  L  ++      WS +  +  +L+++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD
Sbjct:    1 METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKC-VLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFD 348
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Human
Match: NUDC (nuclear distribution C, dynein complex regulator [Source:HGNC Symbol;Acc:HGNC:8045])

HSP 1 Score: 120.553 bits (301), Expect = 5.078e-31
Identity = 97/335 (28.96%), Postives = 160/335 (47.76%), Query Frame = 1 
Query:   16 KDDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKE--IQIYRTVSNDNS----------KISKLENDLIYVADAESY------------------------------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWD 855
            +++E+FD +LL + Q+    +   ++  F FLRR+TD +         +G   G AEKLI   F  H     + L+   R EK    +++  +K E   ++ +   ++ S          +  +L+ ++    DAE++                                    NGA   NY W+QT+ ELD+ V  P  V+     KD+ V ++R+H+ V    Q    ++ID +L  EVK  E  W  +  + K++ + +EK+ +  WW  L   +  INT+KI+  +  +SDLD E ++ + K+MYD RQK +GLPTSD+QK   +LKK  D
Sbjct:    5 QEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQTFSHH-----NQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAV--PFCVNFRLKGKDMVVDIQRRHLRVGLKGQ---PAIIDGELYNEVKVEESSWLIE--DGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 318
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Celegans
Match: nud-1 (Aspergillus NUclear Division related; NUD-1 [Source:UniProtKB/TrEMBL;Acc:G5EE74])

HSP 1 Score: 117.857 bits (294), Expect = 1.760e-30
Identity = 90/306 (29.41%), Postives = 163/306 (53.27%), Query Frame = 1 
Query:   25 EKFDNILLDIIQRVNT-LPNFLDILFGFLRRRTDLYYIMDDKQS------KLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKS-------------ILNQSQESDKKEIQIYRTVSN---------DNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            E+FD++LL + Q+++  +P  LD+LF FL R+TD Y      Q+      K     GKA K   +A KK K+  E  L+    A+K+             + ++   + +KE Q   +V N         + SK +++E++   +    S NGA    Y W+QT+ EL++++ I    +  S+D+ V +E+  +SV   ++N+   ++D  L   +K     W  +  ++ I++++EK+ +  WW      +  INT+++   +  +SDLD E +A + K+MYD RQK++GLPTSD++K + +L++
Sbjct:    5 ERFDSVLLSMAQQLSGGVPEMLDVLFEFLSRKTDFYSGAGVDQARTLLLEKFDKHGGKAMKEAEEA-KKRKEEQERKLAERRAAQKAKEEEEFRNAKVVEVTDEEAAAFEKE-QAKNSVENLEKFVDNEGETSKDAEVEDEDSKLMKPNSGNGADLAKYQWTQTLQELEVKIPIAAGFAIKSRDVVVKIEKTSVSV--GLKNQA-PIVDGKLPHAIKVENCNWVIENGKA-IVLTLEKINDMEWWNRFLDSDPPINTKEVKPENSKLSDLDGETRAMVEKMMYDQRQKEMGLPTSDEKKKHDMLQQ 304
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Fly
Match: CG31251 (gene:FBgn0051251 transcript:FBtr0083484)

HSP 1 Score: 152.91 bits (385), Expect = 9.291e-44
Identity = 92/306 (30.07%), Postives = 165/306 (53.92%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKH-KDIFESSLSNNCRAEKSILNQSQESDKKEIQIYRTVSNDNSKISKLENDLIYVADAES-------YNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHK-----LMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS 897
            D ++ D +L++I+Q   T+  FLD +FGFLRR TD Y+   D+  K+GF  G  ++++  A +++  D    SL+    A+     ++     +E+ +       + ++  +E+        +S        NG + E + WSQT+ +++++  +P+    +K L + ++ +HI V +    ET  +++ +L   +K  E  W+ D  +++++IS +K +E WW+ LF G+  I+++KI+C R + DL +E QA I K     L  D +Q ++   + DQ      LK AWD +GSPFKGQ FD S
Sbjct:    2 DFQRNDAMLMEILQDRKTITGFLDSIFGFLRRNTDFYHTKRDEADKIGFPKGVRDQILYGAMQRYDPDCLLQSLTAEGGADD---GETAPPAVEEVVLESEDGPQDEEMKPIESQPPQKGKEQSKFSPSDYKNGDVFETHCWSQTLKDVEVQALLPKDHQTAKKLHISIQAQHIKVSSKHSPET-IILEGNLSQRIKHKEAVWTID--QNRLIISYDKAKELWWDRLFEGDPEIDSKKIECERYIDDLPEETQATIEKLRVQQLAADKQQNEIQTSSPDQAINLDRLKAAWDAEGSPFKGQPFDPS 301
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Fly
Match: nudC (gene:FBgn0021768 transcript:FBtr0075328)

HSP 1 Score: 119.398 bits (298), Expect = 5.774e-31
Identity = 100/328 (30.49%), Postives = 161/328 (49.09%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQRVNT-LPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKK---------HKDIFESSLSNNCRAEKSILNQS------------------------QESDKKEIQIYRTVSNDNSK-----ISKL------ENDLIYVAD--AESYNGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            ++ KFDNILL + ++ +  +P FL  L  FLRR+TD +          G    + EKL+LD F K         ++ I     S   +AEK    +                         +E  KK  Q+  +   + S      ISK       E+D   +      + NG   ENYTW+QT+ E+++  KIP  ++    ++DL + + +K + V   I+ +T  +ID +LC EVK  E  W     ++ ++I+++K+ +  WW  L   +  I+TRKI+  S  +SDLD E ++ + K+MYD RQK+LGLPTS+ +K   +L+K
Sbjct:    4 EEGKFDNILLAVAEKHHGGVPEFLGTLASFLRRKTDFFT---------GAKQTEWEKLLLDVFNKESKLAVTENYEKIKAREASQRLKAEKERAERKARKQEIDDNKICDITDEEAAAIIKEEETKKRQQLLDSAGGEPSASNRDGISKPIEKVDDESDKSELGKLMPNAGNGCTLENYTWTQTLEEVEL--KIPFNLTFGLRARDLVISIGKKSLKV--GIKGQT-PIIDGELCGEVKTEESVWVLQDSKT-VMITLDKINKMNWWSRLVTTDPEISTRKINPESSKLSDLDGETRSMVEKMMYDQRQKELGLPTSEDRKKQDILEK 316
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Fly
Match: nudC (gene:FBgn0021768 transcript:FBtr0305912)

HSP 1 Score: 119.398 bits (298), Expect = 5.774e-31
Identity = 100/328 (30.49%), Postives = 161/328 (49.09%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQRVNT-LPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKK---------HKDIFESSLSNNCRAEKSILNQS------------------------QESDKKEIQIYRTVSNDNSK-----ISKL------ENDLIYVAD--AESYNGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            ++ KFDNILL + ++ +  +P FL  L  FLRR+TD +          G    + EKL+LD F K         ++ I     S   +AEK    +                         +E  KK  Q+  +   + S      ISK       E+D   +      + NG   ENYTW+QT+ E+++  KIP  ++    ++DL + + +K + V   I+ +T  +ID +LC EVK  E  W     ++ ++I+++K+ +  WW  L   +  I+TRKI+  S  +SDLD E ++ + K+MYD RQK+LGLPTS+ +K   +L+K
Sbjct:    4 EEGKFDNILLAVAEKHHGGVPEFLGTLASFLRRKTDFFT---------GAKQTEWEKLLLDVFNKESKLAVTENYEKIKAREASQRLKAEKERAERKARKQEIDDNKICDITDEEAAAIIKEEETKKRQQLLDSAGGEPSASNRDGISKPIEKVDDESDKSELGKLMPNAGNGCTLENYTWTQTLEEVEL--KIPFNLTFGLRARDLVISIGKKSLKV--GIKGQT-PIIDGELCGEVKTEESVWVLQDSKT-VMITLDKINKMNWWSRLVTTDPEISTRKINPESSKLSDLDGETRSMVEKMMYDQRQKELGLPTSEDRKKQDILEK 316
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Zebrafish
Match: nudcd3 (NudC domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-040426-2255])

HSP 1 Score: 180.259 bits (456), Expect = 7.505e-54
Identity = 102/326 (31.29%), Postives = 165/326 (50.61%), Query Frame = 1 
Query:   25 EKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFE-------------SSLSNNCRAEKSILNQSQESDKKEIQIY------------------RTVSNDNS----KISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS 897
            E +DN LL I+Q V  + NFL + FGFL R+TD Y ++     ++GF PG AE+++   FK  + + E             S+ +     E  + +++QES + E                      R   +DNS    K +  + D +  A+A+SYNGA+ E YTWSQ   ++++RV +   +   + + V ++   +SV        K ++D +    +      WS +     +L+S+ K  E WW A+  GE+ I+  +I+  R M+ +D+E  A + +L +D  QK  G P S + K++ +LKK WD +GSPFKGQEFD S
Sbjct:    9 ELYDNALLGILQHVGNVQNFLQVYFGFLYRKTDFYRLLSGPHDRMGFPPGAAEQMVFKTFKLFEKLAEQDRERTVKLMEEKSAAAPPAVQELELQSETQESRETEDNTAASASSSASAASSSSTDESRNTPDDNSSGAEKTADADKDNVAQANADSYNGAVREKYTWSQDYTDVEVRVHVEPDIIKGRQVCVDLQSSRVSVSVADGGSRKVLLDGEFTHRINTENSLWSLEPGRC-VLLSLSKCSEVWWSAVLKGEAEIDVNQINRERSMATVDEEEHAVLDRLTFDYHQKLQGKPQSHEMKVHDMLKKGWDAEGSPFKGQEFDPS 333
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Zebrafish
Match: nudc (nudC nuclear distribution protein [Source:ZFIN;Acc:ZDB-GENE-040426-899])

HSP 1 Score: 105.145 bits (261), Expect = 1.566e-25
Identity = 96/331 (29.00%), Postives = 149/331 (45.02%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDI-FESSLSNNCRAEKSILNQSQESDK--KEIQIYRTVSNDNSKISKLEND--------------------LIYVADAESY------------------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            DDE+FD +LL + Q+    +   ++  F FLRR+TD +          G   G  EKL+ +AF  H  +  +       R EK    +++ + K  +E    R +  +  +I +L ++                    +    DA+S                         NGA   NY W+Q++ E+D+ V  P  VS     KD+ V V+R+ + V          +ID  L  EVK  E  W  +  + K++ I  EK+ +  WW  L   +  INT+KI C     +SDLD E ++ + K+MYD RQK +GLPTS++QK   +LKK
Sbjct:    4 DDERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------TGGESGAPEKLVKEAFAHHNQLALQVQKEKQSRQEKERKEKAERAAKLKEEEMKKRKIDAEEPRIKELTDEEAERLQSQLQTKQEEQKNSEVAEKTDADSKDKKGSDSEGEEDEKDKDKVKPNAGNGADLPNYRWTQSLSEVDLVV--PFDVSFRLKGKDVVVDVQRRTLKVGLKGH---PPLIDGQLFNEVKVEESSWLIE--DGKVVTIHFEKINKMEWWNKLVTTDPEINTKKI-CPENSKLSDLDGETRSMVEKMMYDQRQKSMGLPTSEEQKKQDILKK 317
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Xenopus
Match: nudcd3 (NudC domain containing 3 [Source:NCBI gene;Acc:548495])

HSP 1 Score: 166.007 bits (419), Expect = 4.435e-48
Identity = 103/336 (30.65%), Postives = 167/336 (49.70%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDI----FESSLSN---------------------------NCRAEKSILNQ------SQESDKKEIQIYRTVSNDNSKISKLE--NDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS 897
            M+ +  +++D+ LL I+Q V  + +FL+I FGFL R+TD Y ++ + Q +LGF PG A+ +++  FK  + +     E  + +                              AE++ L Q       Q+ D K     R  S D +  +  E      Y AD +SYNGAI +NY WSQ   +++I+V +P++V   + ++V +    I V        + +++     ++      WS +  +  I+IS+ K  E WW A+   E  I+  KI+  R M+ +DDE  A + +L +D  QK  G P S + K++ +LKK WD +GSPFKGQ FD S
Sbjct:    1 MEPELSDRYDHALLGILQHVGNIQDFLNIYFGFLYRKTDFYRLLLNPQDRLGFPPGAAQAMVMQTFKTFERLALKDHEQRVCDLQEKLKKKEEKEADTEAAPPPVQEVIIETPAEEATLEQDKAEEEPQQIDTKGRAEGRETSEDCAGQAAAEPKEQEDYQADPDSYNGAIRKNYVWSQDYTDVEIKVPVPKSVIKGRQVSVDLRSSCIRVAVREGGGERVLVEGSFTHKINAETSLWSLEPGKC-IVISLSKCGEVWWNAVLEDEEKIDIDKINKERSMATVDDEEHAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFKGQNFDPS 335
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Xenopus
Match: klf11 (Kruppel-like factor 11 [Source:Xenbase;Acc:XB-GENE-956858])

HSP 1 Score: 112.849 bits (281), Expect = 3.260e-28
Identity = 90/322 (27.95%), Postives = 154/322 (47.83%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLS--NNCRAEKSILNQSQESDKKEIQI--YRTVSNDNSKISKLENDLIYVADAE-------------------------------------SYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            +DE+FD +LL + Q+    +   ++  F FLRR+TD +         +G     AEKLI  AF  H  +  ++    +  R E+  + Q +E+ KKE +    R     + +  +L+ ++    + E                                     S NGA   +Y W+QT+ E+D+ V  P +     KD+ V ++R  +++    Q   K V+D +L  ++K  E  W  +  + K++ + +EK+    WW  + + +  INT+KI+  +  +SDLD E ++ + K+MYD RQK +GLPTSD+QK   +LKK
Sbjct:    6 EDERFDAMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------VGGENAAAEKLITQAFNHHNKLALAAQKQKDADRLEREAVRQEREAKKKETEAGESRITELTDEEAERLQKEIDKNKEKEKATRETEEKPEPEKDGEEEKEEEEEDDEKDKGKLKPNSGNGANLPHYRWTQTLSEVDLVVPFPVSFRLKGKDVQVDIKRHRLTIGLRGQ---KPVLDGELFNDIKVEECSWLIE--DGKVVTVHLEKINTMEWWSRVVLTDPEINTKKINPENSKLSDLDGETRSMVEKMMYDQRQKSMGLPTSDEQKKQDILKK 313
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Mouse
Match: Nudcd3 (NudC domain containing 3 [Source:MGI Symbol;Acc:MGI:2144158])

HSP 1 Score: 129.798 bits (325), Expect = 2.453e-34
Identity = 64/172 (37.21%), Postives = 101/172 (58.72%), Query Frame = 1 
Query:  376 DAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            + +SYNGAI ENY WSQ   +L++RV +P+ V   K ++V +    I V    +N  + +++  L  ++      WS +     +L+++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD
Sbjct:  180 NPDSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQVSVALSSGTIRVAMVEENGERVLMEGKLTHKINTESSLWSLEPGRC-VLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFD 350

HSP 2 Score: 67.0106 bits (162), Expect = 4.894e-12
Identity = 28/67 (41.79%), Postives = 41/67 (61.19%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFK 207
            M+    E +D  LL I+Q V  + +FL +LFGFL R+TD Y ++     ++GF PG A+ L+L  FK
Sbjct:    1 MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFK 67
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Mouse
Match: Nudc (nudC nuclear distribution protein [Source:MGI Symbol;Acc:MGI:106014])

HSP 1 Score: 118.242 bits (295), Expect = 2.342e-30
Identity = 98/331 (29.61%), Postives = 155/331 (46.83%), Query Frame = 1 
Query:   16 KDDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESS---------------------LSNNCRAE------KSILNQSQESDKKEIQIYRTVSNDNSKISKLENDLIYVADAESY-----------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWD 855
            +++E+FD +LL + Q+    +   ++  F FLRR+TD +         +G   G AEKLI   F  H  + + +                     L+   +AE      K + ++  E  + EI   +   +  +++     D     DAE                   NGA   NY W+QT+ ELD+ V  P  VS     KD+ V ++R+H+ V    Q     V+D +L  EVK  E  W  +  + K++ + +EK+ +  WW  L   +  INT+KI+  +  +SDLD E ++ + K+MYD RQK +GLPTSD+QK   +LKK  D
Sbjct:    5 QEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQTFNHHNQLAQKARREKRARQETERREKAERAARLAKEAKAETPGPQIKELTDEEAERLQLEIDQKKDAEDQEAQLKNGSLDSPGKQDAEDEEDEEDEKDKGKLKPNLGNGADLPNYRWTQTLAELDLAV--PFRVSFRLKGKDVVVDIQRRHLRVGLKGQ---PPVVDGELYNEVKVEESSWLIE--DGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 319
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Mouse
Match: Nudcd3 (NudC domain containing 3 [Source:MGI Symbol;Acc:MGI:2144158])

HSP 1 Score: 98.2117 bits (243), Expect = 1.494e-23
Identity = 56/174 (32.18%), Postives = 82/174 (47.13%), Query Frame = 1 
Query:  376 DAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS 897
            + +SYNGAI ENY WSQ   +L++RV +P+ V   K                                                  +++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD +
Sbjct:  116 NPDSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQ-------------------------------------------------VNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPA 240
[Close]
BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Match: sp|Q8IVD9|NUDC3_HUMAN (NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3)

HSP 1 Score: 167.933 bits (424), Expect = 4.629e-48
Identity = 104/349 (29.80%), Postives = 173/349 (49.57%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAF------------KKHKDIFESSLSNNCRAEKSILNQSQESDK-----KEIQIYRTVSND-NSKISKLE-----NDLIY----------VADA---------------------ESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            M+    E +D  LL I+Q V  + +FL +LFGFL R+TD Y ++     ++GF PG A+ L+L  F            K+ +++ E          K++   + E +      +EI+I  T   D + ++ K++      ++ +          VA A                     +SYNGA+ ENYTWSQ   +L++RV +P+ V   K ++V +    I V    +N  + +++  L  ++      WS +  +  +L+++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD
Sbjct:    1 METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDSTTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPDSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKC-VLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFD 348
[Close]
BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Match: sp|Q5RB75|NUDC3_PONAB (NudC domain-containing protein 3 OS=Pongo abelii OX=9601 GN=NUDCD3 PE=2 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 2.871e-34
Identity = 64/172 (37.21%), Postives = 103/172 (59.88%), Query Frame = 1 
Query:  376 DAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            + +SYNGA+ ENYTWSQ   +L++RV +P+ V   K ++V +    I V    +N  + +++  L  ++      WS +  +  +L+++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD
Sbjct:  178 NPDSYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKC-VLVNLSKVGEYWWNAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFD 348

HSP 2 Score: 67.3958 bits (163), Expect = 2.718e-11
Identity = 28/67 (41.79%), Postives = 41/67 (61.19%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFK 207
            M+    E +D  LL I+Q V  + +FL +LFGFL R+TD Y ++     ++GF PG A+ L+L  FK
Sbjct:    1 MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFK 67
[Close]
BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Match: sp|Q8R1N4|NUDC3_MOUSE (NudC domain-containing protein 3 OS=Mus musculus OX=10090 GN=Nudcd3 PE=1 SV=3)

HSP 1 Score: 129.798 bits (325), Expect = 1.716e-33
Identity = 64/172 (37.21%), Postives = 101/172 (58.72%), Query Frame = 1 
Query:  376 DAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            + +SYNGAI ENY WSQ   +L++RV +P+ V   K ++V +    I V    +N  + +++  L  ++      WS +     +L+++ KV E WW A+  GE  I+  KI+  R M+ +D+E QA + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ FD
Sbjct:  180 NPDSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQVSVALSSGTIRVAMVEENGERVLMEGKLTHKINTESSLWSLEPGRC-VLVNLSKVGEYWWSAILEGEEPIDIDKINKERSMATVDEEEQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFD 350

HSP 2 Score: 67.0106 bits (162), Expect = 3.423e-11
Identity = 28/67 (41.79%), Postives = 41/67 (61.19%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFK 207
            M+    E +D  LL I+Q V  + +FL +LFGFL R+TD Y ++     ++GF PG A+ L+L  FK
Sbjct:    1 MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFK 67
[Close]
BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Match: sp|Q9Y266|NUDC_HUMAN (Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 2.438e-30
Identity = 97/335 (28.96%), Postives = 160/335 (47.76%), Query Frame = 1 
Query:   16 KDDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKE--IQIYRTVSNDNS----------KISKLENDLIYVADAESY------------------------------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWD 855
            +++E+FD +LL + Q+    +   ++  F FLRR+TD +         +G   G AEKLI   F  H     + L+   R EK    +++  +K E   ++ +   ++ S          +  +L+ ++    DAE++                                    NGA   NY W+QT+ ELD+ V  P  V+     KD+ V ++R+H+ V    Q    ++ID +L  EVK  E  W  +  + K++ + +EK+ +  WW  L   +  INT+KI+  +  +SDLD E ++ + K+MYD RQK +GLPTSD+QK   +LKK  D
Sbjct:    5 QEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQTFSHH-----NQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAV--PFCVNFRLKGKDMVVDIQRRHLRVGLKGQ---PAIIDGELYNEVKVEESSWLIE--DGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 318
[Close]
BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Match: sp|Q63525|NUDC_RAT (Nuclear migration protein nudC OS=Rattus norvegicus OX=10116 GN=Nudc PE=1 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 7.488e-30
Identity = 98/336 (29.17%), Postives = 158/336 (47.02%), Query Frame = 1 
Query:   16 KDDEKFDNILLDIIQRV-NTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKE--IQIYRTVSND----------NSKISKLENDLIYVADAESY-------------------------------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWD 855
            +++E+FD +LL + Q+    +   ++  F FLRR+TD +         +G   G AEKLI   F  H     + L+   R EK    +++  +K E   ++ +    +          + +  +L+ ++    DAE++                                     NGA   NY W+QT+ ELD+ V  P  VS     KD+ V ++R+H+ V    Q     VID +L  EVK  E  W  +  + K++ + +EK+ +  WW  L   +  INT+KI+  +  +SDLD E ++ + K+MYD RQK +GLPTSD+QK   +LKK  D
Sbjct:    5 QEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFF---------IGGEEGMAEKLITQTFNHH-----NQLAQKARREKRARQETERREKAERAARLAKEAKAETPGPQIKELTDEEAERLQLEIDQKKDAENHEVQLKNGSLDSPGKQDAEEEEDEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAV--PFRVSFRLKGKDVVVDIQRRHLRVGLKGQ---APVIDGELYNEVKVEESSWLIE--DGKVVTVHLEKINKMEWWNRLVTSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMD 319
[Close]
BLAST of NudC domain-containing 3-like vs. TrEMBL
Match: A0A4E0R6N6 (NudC domain-containing protein 3 OS=Fasciola hepatica OX=6192 GN=D915_007998 PE=4 SV=1)

HSP 1 Score: 278.87 bits (712), Expect = 7.425e-89
Identity = 144/328 (43.90%), Postives = 200/328 (60.98%), Query Frame = 1 
Query:   28 KFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFE---------SSLS------------NNCRAEKSILNQSQESDKKEIQIYRTVSNDNSK-ISKLEN----------DLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS--NIDC 909
            ++DN LL I+Q    +  FLD++FGFL RRTD Y+IM   Q+KLGF PG   +++  A++K+K IFE         S LS            N+C   K    + + S      +   +     K   KLE            ++Y AD + YNGA+ + Y WSQTI ++DI+V++P +V  +KDL VLVERK I ++   +NE +   D  LCWE++K+E  W+   KE++I   ++KVQERWWEA F GE  INTRKIDCSRPM +LD+EAQAKI +LMYD + K+ GLPTS+QQK+  +L +AW+ +GSPF+G +FD S  NI C
Sbjct:    4 QYDNALLGILQHEGKIEKFLDVVFGFLMRRTDFYHIMTPDQNKLGFPPGVNFRIVAHAYEKYKSIFEQYERQRAIVSDLSTRPSSKTKETDANSCELAKPPTEELESSTIAAASVNPVLQKPTPKHTPKLEAGEENADDDSVSVVYQADPDCYNGAVRDQYNWSQTIKDVDIKVQVPSSVKTAKDLKVLVERKRIRIVIKQENEEQPYFDRTLCWEIQKDEAVWTLHPKENQIHFCLDKVQERWWEAAFEGEDKINTRKIDCSRPMHELDEEAQAKIQQLMYDEQCKRRGLPTSEQQKIQKMLSEAWNKEGSPFQGTDFDPSKLNIAC 331
[Close]
BLAST of NudC domain-containing 3-like vs. TrEMBL
Match: C1LHS0 (NudC domain-containing protein 3 OS=Schistosoma japonicum OX=6182 GN=EWB00_003084 PE=2 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 1.593e-88
Identity = 136/310 (43.87%), Postives = 207/310 (66.77%), Query Frame = 1 
Query:   22 DEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSL----SNNCRAEKSILNQSQESDK----------KEIQIYRTVSNDNSKISKLEND--LIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNI 903
            D ++DN LL I+Q    L  FLD++FGFL RRTD +YIM  +Q  +GFSPG + ++IL A++K+K IF++      + + ++ K+I + ++E  K           +  +    SN  S  SK E +   +Y AD + YNGA  +NYTWSQTI ++DI++K+P++V N++ ++V +ERKHI +      +     D DLCW++ KN+  W+F  KE++I + ++K+QERWWEA F GE  INTRKIDCSRPM +LDDEAQAKI +LMYD ++K+ GL TS+Q+K+ ++L  AW+ +GSPF+G ++D + +
Sbjct:    5 DTQYDNALLGILQNEGKLEKFLDVIFGFLMRRTDFFYIMTPEQRNIGFSPGVSIQMILKAYEKYKTIFDNYQRRREAESNQSTKTITSITKEEPKNTNIPVSPPSSDKDVCDCPSNSTSSGSKNEENESRVYQADPDCYNGATRDNYTWSQTIKDIDIKIKVPESVMNARCVSVNIERKHIRISIRQNGKETVYFDRDLCWDIHKNDAMWTFHSKENQIHLCLDKIQERWWEAAFDGEDKINTRKIDCSRPMHELDDEAQAKIQQLMYDEQRKRQGLLTSEQEKIQNILASAWNKEGSPFQGTQYDPTKV 314
[Close]
BLAST of NudC domain-containing 3-like vs. TrEMBL
Match: Q5DAE2 (NudC domain-containing protein isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_003084 PE=2 SV=1)

HSP 1 Score: 273.863 bits (699), Expect = 4.440e-87
Identity = 139/319 (43.57%), Postives = 206/319 (64.58%), Query Frame = 1 
Query:   22 DEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFES-----SLSNNCRAEKSILNQSQES----DKKEIQ--------------IYRTVSNDNSKISKLEND--LIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNI 903
            D ++DN LL I+Q    L  FLD++FGFL RRTD +YIM  +Q  +GFSPG + ++IL A++K+K IF++        +N    KS+ N   E+     K+E +              +    SN  S  SK E +   +Y AD + YNGA  +NYTWSQTI ++DI++K+P++V N++ ++V +ERKHI +      +     D DLCW++ KN+  W+F  KE++I + ++K+QERWWEA F GE  INTRKIDCSRPM +LDDEAQAKI +LMYD ++K+ GL TS+Q+K+ ++L  AW+ +GSPF+G ++D + +
Sbjct:    5 DTQYDNALLGILQNEGKLEKFLDVIFGFLMRRTDFFYIMTPEQRNIGFSPGVSIQMILKAYEKYKTIFDNYQRRREAESNQSTSKSLSNFISETITSITKEEPKNTNIPVSPPSSDKDVCDCPSNSTSSGSKNEENESRVYQADPDCYNGATRDNYTWSQTIKDIDIKIKVPESVMNARCVSVNIERKHIRISIRQNGKETVYFDRDLCWDIHKNDAMWTFHSKENQIHLCLDKIQERWWEAAFDGEDKINTRKIDCSRPMHELDDEAQAKIQQLMYDEQRKRQGLLTSEQEKIQNILASAWNKEGSPFQGTQYDPTKV 323
[Close]
BLAST of NudC domain-containing 3-like vs. TrEMBL
Match: A0A504Z485 (NudC domain-containing protein 3 OS=Fasciola gigantica OX=46835 GN=FGIG_08291 PE=4 SV=1)

HSP 1 Score: 270.781 bits (691), Expect = 1.472e-85
Identity = 142/342 (41.52%), Postives = 199/342 (58.19%), Query Frame = 1 
Query:   28 KFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKL--------------ILDAFKKHKDIFES---------------------SLSNNCRAEKSILNQSQESDKKEIQIYRTVSNDNSK-ISKLEN----------DLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLS--NIDC 909
            ++DN LL I+Q    +  FLD++FGFL RRTD Y+IM   Q+KLGF PG   ++              I  A++K+K IFE                      + SN+C   K    + + S      +   +     K   KLE            ++Y AD + YNGA+ + Y WSQTI ++DI+V++P +V  +KDL VLVERK I ++   +NE +   D  LCWE++K+E  W+   KE+++   ++KVQERWWEA F GE  INTRKIDCSRPM +LD+EAQAKI +LMYD + K+ GLPTS+QQK+  +L +AW+ +GSPF+G +FD S  NI C
Sbjct:    4 QYDNALLGILQHEGKIEKFLDVVFGFLMRRTDFYHIMTPDQNKLGFPPGVNFRIVAHVSPSHFLRHIQIFQAYEKYKSIFEQYERQRAIVSDLSTRPSSKTKETGSNSCELAKPRTEELESSTIATASVNPVLQKPTPKHTPKLEAGEENADDDSVSVVYQADPDCYNGAVRDQYNWSQTIKDVDIKVQVPSSVKTAKDLKVLVERKRIRIVIKQENEEQPYFDRTLCWEIQKDEAVWTLHPKENQVHFCLDKVQERWWEAAFEGEDKINTRKIDCSRPMHELDEEAQAKIQQLMYDEQCKRRGLPTSEQQKIQKMLSEAWNKEGSPFQGTDFDPSKVNIAC 345
[Close]
BLAST of NudC domain-containing 3-like vs. TrEMBL
Match: A0A4S2M5Y8 (CS domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002442 PE=4 SV=1)

HSP 1 Score: 269.24 bits (687), Expect = 4.587e-85
Identity = 131/332 (39.46%), Postives = 202/332 (60.84%), Query Frame = 1 
Query:   31 FDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFES-------SLSNNCRAEKS----ILNQSQESDKKEIQIYRT---------------------VSNDNSKISKL---------ENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNI 903
            +D+ LL I+Q    +  FLD++FGFL RRTD Y+IM  +Q KLGF PG   ++++ AF+++K +FE        ++++  ++ KS    I      +D+K  +   T                      S+ +SK ++          E  L+Y AD + YNGA  ENYTWSQ+I ++DI+VK+P  +   +DL + ++RKHI ++       +   + +LCWE+  ++  W+FD +E ++   ++KV+ERWW+A F GE  INTRKIDCSRPM +LD+E+QAKIH+LMYD   K+ GLPTS+++K++ +L KAWD++GSPF+G  FD S I
Sbjct:   11 YDSALLGILQHEGKIEKFLDVIFGFLMRRTDFYHIMTAEQKKLGFPPGVNLRMVVQAFERYKSMFEEYNRQHMEAVADKVQSTKSKKQVIGRHPPTADRKTTEAASTDDFVVPVPDSTQVTTAATDEKHSSGDSKPTEQTSTKENTEEEGPLVYQADPDCYNGAERENYTWSQSIKDVDIKVKVPNTIKTGRDLKIAIDRKHIRILLVPSGSKEPYFNRELCWEISTDDAVWTFDPEEGQVQFCLDKVEERWWDAAFEGEDKINTRKIDCSRPMHELDEESQAKIHQLMYDQECKRKGLPTSEEKKVHDILAKAWDVEGSPFRGTPFDPSKI 342
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Cavefish
Match: nudcd3 (NudC domain containing 3 [Source:NCBI gene;Acc:103040649])

HSP 1 Score: 130.568 bits (327), Expect = 1.071e-34
Identity = 61/181 (33.70%), Postives = 107/181 (59.12%), Query Frame = 1 
Query:  364 IYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNID 906
            +Y A+++SYNGA+ ENY+WSQ   ++++RV +P ++   + ++V ++   + V        K +++ +   ++      WS +  +  +L+S+ K  E WW A+  GE  I+  +I+  R M+ +D+E  A + +L +D  QK  G P S + K++ +LKK WD +GSPFKGQ+FD S  D
Sbjct:  191 VYQANSDSYNGAVRENYSWSQDYTDVEVRVFVPPSIVKGRQVSVNLQCGSVRVAVKEGASEKVLLEGEFTHKINTENSLWSLEPGQC-VLLSLSKTGEVWWSAVLKGEQEIDVNQINRERSMASVDEEEHAVLDRLTFDYHQKLQGKPQSHEMKVHDMLKKGWDAEGSPFKGQQFDPSMFD 370

HSP 2 Score: 74.7146 bits (182), Expect = 1.107e-14
Identity = 31/61 (50.82%), Postives = 40/61 (65.57%), Query Frame = 1 
Query:   25 EKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFK 207
            E +DN LL I+Q V  + NFL I FGFL R+TD Y +M     ++GF PG AEK++L  FK
Sbjct:    9 ELYDNALLGILQHVGNIQNFLQIFFGFLYRKTDFYRLMSSSTDRMGFPPGVAEKMVLKTFK 69
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Cavefish
Match: nudc (nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:103045763])

HSP 1 Score: 94.7449 bits (234), Expect = 5.103e-22
Identity = 87/305 (28.52%), Postives = 137/305 (44.92%), Query Frame = 1 
Query:   19 DDEKFDNILLDIIQRV-NTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAF--------KKHKDIFESSLSNNCRAEKSILNQSQE-----------------SDKKEIQIYRTVSNDNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLK 843
            D+EK+D +LL + Q+    +   ++  F FLRR+TD +          G   G  E+L+ +AF        + HKD             +       E                 +D++  ++   +    S+  + E D   V    S NGA   NY W+Q++ E+D+ V          KD+ V V+R+ + V          VID  L  EVK  E  W  +  +  + + +EK+ +  WW  L   +  INT+KI C     +SDLD E ++ + K+MYD RQK +GLPTS++QK   +LK
Sbjct:    4 DEEKYDGMLLVMAQQHEGGVQELVNTFFSFLRRKTDFF---------TGGESGAPERLVKEAFAHHSQLALQAHKDKQSKQEKEKKEKAERAAKLKAEEERKKKELENEPRIKELTDEEAERLQTEIDQSESEGEEDEKDKNKVK-PNSGNGADLPNYRWTQSLSEVDLIVPFDVKFRLKGKDVVVDVQRRSLKVGLKGH---PPVIDAALFNEVKVEESSWLIEDGKV-VTVHLEKINKMEWWNKLVTTDPEINTKKI-CPENSKLSDLDGETRSMVEKMMYDQRQKSMGLPTSEEQKKQDILK 293
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Cavefish
Match: nudc (nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:103045763])

HSP 1 Score: 87.8113 bits (216), Expect = 2.371e-19
Identity = 60/159 (37.74%), Postives = 88/159 (55.35%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            S NGA   NY W+Q++ E+D+ V          KD+ V V+R+ + V          VID  L  EVK  E  W  +  + K++ + +EK+ +  WW  L   +  INT+KI C     +SDLD E ++ + K+MYD RQK +GLPTS++QK   +LKK
Sbjct:  160 SGNGADLPNYRWTQSLSEVDLIVPFDVKFRLKGKDVVVDVQRRSLKVGLKGH---PPVIDAALFNEVKVEESSWLIE--DGKVVTVHLEKINKMEWWNKLVTTDPEINTKKI-CPENSKLSDLDGETRSMVEKMMYDQRQKSMGLPTSEEQKKQDILKK 312
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Cavefish
Match: nudc (nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:103045763])

HSP 1 Score: 87.8113 bits (216), Expect = 2.648e-19
Identity = 59/158 (37.34%), Postives = 86/158 (54.43%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            S NGA   NY W+Q++ E+D+ V          KD+ V V+R+ + V          VID  L  EVK  E  W  +  +  + + +EK+ +  WW  L   +  INT+KI C     +SDLD E ++ + K+MYD RQK +GLPTS++QK   +LKK
Sbjct:  169 SGNGADLPNYRWTQSLSEVDLIVPFDVKFRLKGKDVVVDVQRRSLKVGLKGH---PPVIDAALFNEVKVEESSWLIEDGKV-VTVHLEKINKMEWWNKLVTTDPEINTKKI-CPENSKLSDLDGETRSMVEKMMYDQRQKSMGLPTSEEQKKQDILKK 321
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Sea Lamprey
Match: nudcd3 (NudC domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-040426-2255])

HSP 1 Score: 122.865 bits (307), Expect = 1.923e-32
Identity = 59/170 (34.71%), Postives = 100/170 (58.82%), Query Frame = 1 
Query:  382 ESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFD 891
            +SYNGA+ ENY WSQ   +L+I+V +P+ +   K +++ +++  + V    Q E   +++  L   +      WS +  +  I +++ KV E WW A+  GE  I+  +I+  R M+ +D+E  A + +L +D  QK  G P S + K++ +LKK WD +GSPFKGQ+F+
Sbjct:  197 DSYNGAVRENYVWSQDFTDLEIKVFVPKTIVRGKQVSINIQKNSLRVAIREQAEEVVLMEGKLTHNINIESSMWSLEPGKC-IQVNLNKVGEYWWNAVLEGEEPIDIDRINKERSMATVDEEEHAVLDRLTFDYHQKMHGRPQSHEMKVHEMLKKGWDAEGSPFKGQKFE 365

HSP 2 Score: 62.7734 bits (151), Expect = 2.446e-11
Identity = 27/60 (45.00%), Postives = 38/60 (63.33%), Query Frame = 1 
Query:   31 FDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKK 210
            +D  LL ++Q    +  FLD++FGFL RRTD Y +M  +  +LGF PG AE++   AF K
Sbjct:   11 YDQALLGVLQHEGNIEAFLDVVFGFLYRRTDFYRLMLTQGDRLGFPPGVAERIAQRAFFK 70
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Sea Lamprey
Match: nudc (nudC nuclear distribution protein [Source:ZFIN;Acc:ZDB-GENE-040426-899])

HSP 1 Score: 97.0561 bits (240), Expect = 2.230e-23
Identity = 94/344 (27.33%), Postives = 144/344 (41.86%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQR-VNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFK-------------------------------------------KHKDIFESSLSNNCRAEKSILNQSQESDKKEIQIYRTVSNDNSKISKLENDLIYVADAESY-----------NGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVER--------KHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            M   D+E+FD ILL + Q+    +   LD +F FLRR+TD +         +G     AEKL+L+ F+                                           K   I E +     R ++ I      SDKKE Q      N  S++  +E       + E             NGA   NY W+QT+ E+D+R  +  A +  K L   V+         K    I+N++  +   +   L W +++  V  S       +   I K++  WW  L + +  INTRK++  +  +SDLD E ++ + K+MYD RQK +GLPTS+ QK   +LKK
Sbjct:    2 MAASDEERFDGILLAMAQQHEGGVQQMLDTIFSFLRRKTDFF---------VGGEKAAAEKLLLECFRRHEKAALAGERERAREREERQRRDAEERTRRRQQQEQLDDAQAKEPRIQEVTDEEAQRIQREIDQVRARSDKKERQ-----KNGQSRLPGVEPAPDKEDEEEDEKDKGKLKPNVGNGADLANYRWTQTLSEVDVRA-LAAARATGKGLIGPVQSLTLNRLGMKFRCQISNLRAVSDVWVVGSLTWILERVFVITS-------VTSHINKME--WWSRLVVSDPEINTRKVNPENSKLSDLDGETRSMVEKMMYDQRQKAMGLPTSEDQKKQDILKK 321
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Nematostella
Match: EDO38002 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEA5])

HSP 1 Score: 129.413 bits (324), Expect = 1.261e-36
Identity = 65/180 (36.11%), Postives = 106/180 (58.89%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVI--ANIQNETKS----VIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNID 906
             YNGA  E+Y W+QTI ++DI+V +P  V  ++D+ V ++   + V    ++  + K     ++D  L   VK  E  WS +  +  + I++EK +ER+W  +  G+  I+  KID +R + D D++ Q    ++MYD RQKQ+G PT  +Q+ + +LKKAW+  GSPF G  FD S ++
Sbjct:    2 CYNGAALEDYVWAQTIHDIDIKVPVPSCVKKARDVGVEIKNSSLKVFLKGSVPPDGKVAFTILVDGQLQRHVKCEECMWSLEPGKC-VAINLEKTEERFWTTVIKGDPEIDRTKIDTTRDIHDFDEQTQTDYEQVMYDYRQKQMGKPTVKEQQTHEMLKKAWNAKGSPFAGTPFDPSKLN 180
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Nematostella
Match: EDO29367 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3U5])

HSP 1 Score: 105.145 bits (261), Expect = 1.310e-27
Identity = 55/154 (35.71%), Postives = 90/154 (58.44%), Query Frame = 1 
Query:  361 LIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQ 822
            L+     + YNGA  E+Y W+QTI ++DI+V +P  V  ++D  V VE K+ S+   ++  +  ++D  L   VK  E  WS +  +  + I++EK +ER+W  +  G+  I+  KID +R + D D++ Q    ++MYD RQKQ+G PT  +Q
Sbjct:    9 LLPGTQPDCYNGAALEDYVWAQTIHDIDIKVPVPSCVKKARD--VGVEIKNSSLKVFLKGRSTILVDGQLQRHVKCEECMWSLEPGKC-VAINLEKTEERFWTTVIKGDPEIDRTKIDTTRDIHDFDEQTQTDYEQVMYDYRQKQMGKPTVKEQ 159
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Nematostella
Match: EDO46710 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPB6])

HSP 1 Score: 102.449 bits (254), Expect = 2.992e-25
Identity = 63/159 (39.62%), Postives = 95/159 (59.75%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQE-RWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            + NGA   NY W+QT+ E+++R  IP  VS     KD+ V +++KH+   A ++     +ID D   +VK  E  W  D K   +++++EKV +  WW  L   +  INT+K+   +  +SDLD E +  + K+M+D RQKQ+GLPTSD+QK   VLKK
Sbjct:  148 AGNGADLPNYKWTQTLEEIELR--IPLDVSFKPKGKDVVVDIQQKHLK--AGLKGHP-PIIDGDFPKKVKLEECTWLIDGKN--LVLNLEKVNKMEWWSQLVTSDPEINTKKVQPENSKLSDLDGETRGMVEKMMFDQRQKQMGLPTSDEQKKQDVLKK 299
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Medaka
Match: nudcd3 (NudC domain containing 3 [Source:NCBI gene;Acc:101165327])

HSP 1 Score: 158.688 bits (400), Expect = 1.351e-45
Identity = 101/342 (29.53%), Postives = 158/342 (46.20%), Query Frame = 1 
Query:   13 LKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDA--FKKHKDIFESSLSNNCRAEKSI-----------------LNQSQESDKKEIQIYRTVSNDNSKISKLENDL----------------IYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL---------ISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNID 906
            L+  E +DN LL I+Q V  + +FL + FGFL R+TD Y ++     ++GF PG AEK++L     K  + +  + L + CR    +                 L  S E  K E +         S  S+  + L                ++ A+ +SYNGA  ENY+WSQ   ++++RV +P+ V   + ++        S I    +E     +  L            F RKE  +          +S+ K  E WW A+  GE  I+  +I+  R M+ +D+E  A + +L +D  QK  G P S + K++ +LKK WD +GSPF+GQ+FD S  D
Sbjct:    5 LEMTEMYDNALLGILQHVGNIQDFLRVYFGFLYRKTDFYRLLSGPDDRMGFPPGVAEKMVLKVKFCKGARGVARAFLPSVCRERTKVSDLNAEESRGVPPAVQELQVSSEPPKAEERSSVEAPQPESAASEAPDALPGRARLLTGLFFRNQDMFQANPDSYNGAQRENYSWSQDYTDVEVRVFVPKTVVRGRQVSPSRCAARRSAIRPAASECPRRTNRAL------------FTRKERSLRAHVGVCDSQLSLSKTSETWWNAVLKGEEEIDINRINRERSMATVDEEEHAVLDRLTFDYHQKLQGKPQSHEMKVHDMLKKGWDAEGSPFRGQQFDPSMFD 334
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Medaka
Match: nudc (nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:101169957])

HSP 1 Score: 89.7373 bits (221), Expect = 6.357e-20
Identity = 59/159 (37.11%), Postives = 87/159 (54.72%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            S NGA   NY W+QT+ E+D+ V          KD+ V V+R+ I V          V++  L  EVK  E  W  D  + K++ + +EK+ +  WW  +   +  +NT+KI C     +SDLD E +  + K+MYD RQK +GLPTS++QK   +LKK
Sbjct:  207 SGNGADLPNYKWTQTLSEVDLSVPFDVKFRIKGKDVVVDVQRRSIKVGLKGH---PPVVEGQLYNEVKVEESSWLID--DGKVVNVHLEKINKMEWWSRIVTTDPEMNTKKI-CPENSKLSDLDGETRGMVEKMMYDQRQKSMGLPTSEEQKKQDILKK 359
[Close]
BLAST of NudC domain-containing 3-like vs. Ensembl Medaka
Match: nudc (nuclear distribution C, dynein complex regulator [Source:NCBI gene;Acc:101169957])

HSP 1 Score: 89.3521 bits (220), Expect = 6.457e-20
Identity = 59/159 (37.11%), Postives = 87/159 (54.72%), Query Frame = 1 
Query:  385 SYNGAIGENYTWSQTIGELDIRVKIPQAVS-NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKIL-ISIEKVQE-RWWEALFIGESTINTRKIDCSR--PMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            S NGA   NY W+QT+ E+D+ V          KD+ V V+R+ I V          V++  L  EVK  E  W  D  + K++ + +EK+ +  WW  +   +  +NT+KI C     +SDLD E +  + K+MYD RQK +GLPTS++QK   +LKK
Sbjct:  157 SGNGADLPNYKWTQTLSEVDLSVPFDVKFRIKGKDVVVDVQRRSIKVGLKGH---PPVVEGQLYNEVKVEESSWLID--DGKVVNVHLEKINKMEWWSRIVTTDPEMNTKKI-CPENSKLSDLDGETRGMVEKMMYDQRQKSMGLPTSEEQKKQDILKK 309
[Close]
BLAST of NudC domain-containing 3-like vs. Planmine SMEST
Match: SMESG000064942.1 (SMESG000064942.1)

HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0
Identity = 304/306 (99.35%), Postives = 304/306 (99.35%), Query Frame = 1 
Query:    7 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKEIQIYRTVSNDNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNIDCVDKGN 924
            MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKEIQI  TVSNDNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNIDCVDKGN
Sbjct:    1 MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKEIQIDSTVSNDNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVKIPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNIDCVDKGN 306
[Close]
BLAST of NudC domain-containing 3-like vs. Planmine SMEST
Match: SMESG000036795.1 (SMESG000036795.1)

HSP 1 Score: 102.834 bits (255), Expect = 4.952e-25
Identity = 92/319 (28.84%), Postives = 154/319 (48.28%), Query Frame = 1 
Query:   22 DEKFDNILLDIIQRV--NTLPNFLDILFGFLRRRTDLYYIMDDKQSKLGFSPGKAEKLILDAFKKHKD---IFESSLSNNCRAEKSILNQSQESDKKEIQ--IYRTVSNDNSKISKLENDLIYVADAESY--------------------------------NGAIGENYTWSQTIGELDIRVKIPQAVS---NSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWSFDRKESKILISIEKV-QERWWEALFIGESTINTRKIDC-SRPMSDLDDEAQAKIHKLMYDNRQKQLGLPTSDQQKMNSVLKK 846
            ++KFDN+ L I Q+     +   L+  FGFL RRTD +Y         G +  +A K++ DAF+ H+       +        +  +    QES+ K+IQ    R V   N +  K++ ++    DAE +                                NGA      W Q++ ++DIR  IP  V+    S+D+ V +++K+ISV        + +++  L  ++K  E  W+ +  +  I +S+EKV Q  WW  +   +  INT+K++  +  +SDLD E ++ + K+MYD RQK++GLPTS+ QK   +L+K
Sbjct:    3 NDKFDNLFLSIAQQCEEGGIKELLNCFFGFLGRRTDFFY---------GVAKEEAFKVVTDAFEVHQKQSIAKHNKEKKEREEKDKLKKLKQESEIKKIQDNEPRVVELTNEEAEKMQAEI----DAEKHKDMEVDIKPEVKEEEDPDEDPKDKGKLKPNEGNGADLPECKWVQSLKDVDIR--IPTKVNFPVKSRDVIVNIQKKYISVSLKGH---QPLLEGTLYNDIKVEESTWTIEDGKV-IYLSLEKVNQMEWWNRVTDKQPEINTKKVNPENSKLSDLDGETRSMVEKMMYDQRQKEMGLPTSEDQKKQDLLQK 302
The following BLAST results are available for this feature:
BLAST of NudC domain-containing 3-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
NUDCD39.638e-4929.80NudC domain containing 3 [Source:HGNC Symbol;Acc:H... [more]
NUDC5.078e-3128.96nuclear distribution C, dynein complex regulator [... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nud-11.760e-3029.41Aspergillus NUclear Division related; NUD-1 [Sour... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
CG312519.291e-4430.07gene:FBgn0051251 transcript:FBtr0083484[more]
nudC5.774e-3130.49gene:FBgn0021768 transcript:FBtr0075328[more]
nudC5.774e-3130.49gene:FBgn0021768 transcript:FBtr0305912[more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nudcd37.505e-5431.29NudC domain containing 3 [Source:ZFIN;Acc:ZDB-GENE... [more]
nudc1.566e-2529.00nudC nuclear distribution protein [Source:ZFIN;Acc... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nudcd34.435e-4830.65NudC domain containing 3 [Source:NCBI gene;Acc:548... [more]
klf113.260e-2827.95Kruppel-like factor 11 [Source:Xenbase;Acc:XB-GENE... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Nudcd32.453e-3437.21NudC domain containing 3 [Source:MGI Symbol;Acc:MG... [more]
Nudc2.342e-3029.61nudC nuclear distribution protein [Source:MGI Symb... [more]
Nudcd31.494e-2332.18NudC domain containing 3 [Source:MGI Symbol;Acc:MG... [more]
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BLAST of NudC domain-containing 3-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IVD9|NUDC3_HUMAN4.629e-4829.80NudC domain-containing protein 3 OS=Homo sapiens O... [more]
sp|Q5RB75|NUDC3_PONAB2.871e-3437.21NudC domain-containing protein 3 OS=Pongo abelii O... [more]
sp|Q8R1N4|NUDC3_MOUSE1.716e-3337.21NudC domain-containing protein 3 OS=Mus musculus O... [more]
sp|Q9Y266|NUDC_HUMAN2.438e-3028.96Nuclear migration protein nudC OS=Homo sapiens OX=... [more]
sp|Q63525|NUDC_RAT7.488e-3029.17Nuclear migration protein nudC OS=Rattus norvegicu... [more]
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BLAST of NudC domain-containing 3-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4E0R6N67.425e-8943.90NudC domain-containing protein 3 OS=Fasciola hepat... [more]
C1LHS01.593e-8843.87NudC domain-containing protein 3 OS=Schistosoma ja... [more]
Q5DAE24.440e-8743.57NudC domain-containing protein isoform 1 OS=Schist... [more]
A0A504Z4851.472e-8541.52NudC domain-containing protein 3 OS=Fasciola gigan... [more]
A0A4S2M5Y84.587e-8539.46CS domain-containing protein OS=Opisthorchis felin... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
nudcd31.071e-3433.70NudC domain containing 3 [Source:NCBI gene;Acc:103... [more]
nudc5.103e-2228.52nuclear distribution C, dynein complex regulator [... [more]
nudc2.371e-1937.74nuclear distribution C, dynein complex regulator [... [more]
nudc2.648e-1937.34nuclear distribution C, dynein complex regulator [... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nudcd31.923e-3234.71NudC domain containing 3 [Source:ZFIN;Acc:ZDB-GENE... [more]
nudc2.230e-2327.33nudC nuclear distribution protein [Source:ZFIN;Acc... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of NudC domain-containing 3-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO380021.261e-3636.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO293671.310e-2735.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO467102.992e-2539.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of NudC domain-containing 3-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
nudcd31.351e-4529.53NudC domain containing 3 [Source:NCBI gene;Acc:101... [more]
nudc6.357e-2037.11nuclear distribution C, dynein complex regulator [... [more]
nudc6.457e-2037.11nuclear distribution C, dynein complex regulator [... [more]
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BLAST of NudC domain-containing 3-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000064942.10.000e+099.35SMESG000064942.1[more]
SMESG000036795.14.952e-2528.84SMESG000036795.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001822 ID=SMED30001822|Name=NudC domain-containing 3-like|organism=Schmidtea mediterranea sexual|type=transcript|length=962bp
ATTTAAATGGATTTAAAAGATGATGAAAAATTTGATAATATATTATTGGA
CATTATTCAACGGGTTAATACTCTTCCTAATTTTTTGGACATATTGTTTG
GATTTTTAAGAAGAAGAACTGACTTATATTATATAATGGATGATAAACAA
TCTAAACTCGGGTTTTCCCCGGGTAAGGCGGAAAAATTAATTTTGGATGC
ATTTAAGAAACATAAAGACATATTTGAGTCTTCTCTATCAAATAATTGTC
GAGCCGAAAAATCTATTCTTAACCAATCTCAAGAGTCTGATAAGAAAGAA
ATTCAAATTTATAGAACTGTGTCGAATGACAATAGTAAAATATCGAAACT
TGAAAACGATTTAATTTATGTTGCTGACGCGGAGTCATACAATGGAGCGA
TTGGGGAAAATTATACTTGGAGTCAAACAATTGGTGAATTAGATATTCGT
GTTAAAATTCCACAGGCTGTATCAAACAGTAAAGATCTGACAGTGCTAGT
AGAGAGAAAGCATATCAGTGTGATTGCTAATATCCAAAATGAGACTAAGT
CCGTAATTGATAACGATTTATGTTGGGAAGTAAAAAAAAATGAAGTGTTT
TGGTCGTTTGATCGCAAGGAGAGTAAAATTTTAATATCCATAGAAAAAGT
CCAAGAACGTTGGTGGGAAGCTCTGTTTATCGGGGAATCTACGATTAATA
CTCGTAAAATCGACTGCAGTCGTCCGATGTCTGATCTGGATGATGAGGCT
CAGGCTAAAATCCATAAATTAATGTATGATAATCGCCAGAAACAATTGGG
TCTTCCTACTAGCGATCAGCAAAAAATGAACAGTGTGCTAAAGAAGGCAT
GGGATTTGGACGGCTCTCCATTCAAAGGGCAAGAATTCGATCTTTCAAAT
ATCGATTGTGTTGATAAAGGAAATTAATTTTAATAAAATAGCTCGATTTT
CTTTAAAAAAAA
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protein sequence of SMED30001822-orf-1

>SMED30001822-orf-1 ID=SMED30001822-orf-1|Name=SMED30001822-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=307bp
MDLKDDEKFDNILLDIIQRVNTLPNFLDILFGFLRRRTDLYYIMDDKQSK
LGFSPGKAEKLILDAFKKHKDIFESSLSNNCRAEKSILNQSQESDKKEIQ
IYRTVSNDNSKISKLENDLIYVADAESYNGAIGENYTWSQTIGELDIRVK
IPQAVSNSKDLTVLVERKHISVIANIQNETKSVIDNDLCWEVKKNEVFWS
FDRKESKILISIEKVQERWWEALFIGESTINTRKIDCSRPMSDLDDEAQA
KIHKLMYDNRQKQLGLPTSDQQKMNSVLKKAWDLDGSPFKGQEFDLSNID
CVDKGN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006366transcription from RNA polymerase II promoter
Vocabulary: molecular function
TermDefinition
GO:0046982protein heterodimerization activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR037898NudC_fam
IPR025934NudC_N_dom
IPR007052CS_dom
IPR008978HSP20-like_chaperone
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR025934NudC N-terminal domainPFAMPF14050Nudc_Ncoord: 8..67
e-value: 4.1E-20
score: 71.5
IPR007052CS domainPFAMPF04969CScoord: 135..214
e-value: 8.9E-9
score: 36.3
IPR007052CS domainPROSITEPS51203CScoord: 131..224
score: 14.047
IPR008978HSP20-like chaperoneGENE3DG3DSA:2.60.40.790coord: 127..256
e-value: 2.1E-26
score: 94.4
IPR008978HSP20-like chaperoneSUPERFAMILYSSF49764HSP20-like chaperonescoord: 122..237
IPR037898NudC familyPANTHERPTHR12356NUCLEAR MOVEMENT PROTEIN NUDCcoord: 5..113
coord: 92..297
NoneNo IPR availablePANTHERPTHR12356:SF19NUDC DOMAIN CONTAINING 3coord: 92..297
NoneNo IPR availablePANTHERPTHR12356:SF19NUDC DOMAIN CONTAINING 3coord: 5..113
NoneNo IPR availableCDDcd06467p23_NUDC_likecoord: 136..224
e-value: 4.98008E-16
score: 69.8838