Zgc:100846

Overview
NameZgc:100846
Smed IDSMED30001805
Length (bp)1814
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Zgc:100846 (SMED30001805) t-SNE clustered cells

Violin plots show distribution of expression levels for Zgc:100846 (SMED30001805) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Zgc:100846 (SMED30001805) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Zgc:100846 (SMED30001805) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001805

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000031124.1 Contig1057newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000031124.1 Contig1057uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000031124.1 Contig41036newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000031124.1 Contig41036uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000017766.1 Contig1057newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001805SMESG000017766.1 Contig1057uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
zeta neoblastSMED30001805SMESG000031124.1 dd_Smed_v4_6804_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Zgc:100846 vs. Ensembl Human
Match: C9orf72 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 81.6481 bits (200), Expect = 8.974e-16
Identity = 118/495 (23.84%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++     G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. Ensembl Human
Match: C9orf72 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 81.6481 bits (200), Expect = 8.974e-16
Identity = 118/495 (23.84%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++     G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. Ensembl Human
Match: C9orf72 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 75.8702 bits (185), Expect = 6.731e-14
Identity = 118/506 (23.32%), Postives = 200/506 (39.53%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKN-----------IHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y                +    I +D  +   L K F+ ++     G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLFMCTCAGVLYRNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 478
[Close]
BLAST of Zgc:100846 vs. Ensembl Human
Match: C9orf72 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 67.0106 bits (162), Expect = 2.894e-11
Identity = 87/341 (25.51%), Postives = 137/341 (40.18%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQ 1055
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQ 317
[Close]
BLAST of Zgc:100846 vs. Ensembl Human
Match: C9orf72 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 66.2402 bits (160), Expect = 7.205e-11
Identity = 87/341 (25.51%), Postives = 137/341 (40.18%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQ 1055
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQ 317
[Close]
BLAST of Zgc:100846 vs. Ensembl Celegans
Match: alfa-1 (ALS/FTD Associated gene homolog [Source:UniProtKB/TrEMBL;Acc:Q95QK5])

HSP 1 Score: 51.9878 bits (123), Expect = 1.288e-6
Identity = 47/235 (20.00%), Postives = 111/235 (47.23%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQF---SVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQ 1088
            ++ K I+S    ++V +F+F+   +    I+ + +SF+     ++  L         +  ++P ++      D D ++   T  ++ L+ +L +L++F   S+   + ++ T F+           L+ AI   L + G +++IG+D  L+  ++ TLA F+P   +  C+     ++  +   + +QG+ +  +  V     S  S  +P+ +I+++   V  S +Y  H+ ++
Sbjct:  372 LQHKMIVSPSRHLLVAAFIFSVQTKSGSTIT-YAISFLMSHLKQEWYLDRHSWFERMVGDSVPKMKASLFSEDSDDVLVRVTSELSRLLSLLSALERFPLVSLERPLMIKNTLFTDRGISISENRLLAKAISGCLQSQGHTVIIGSDHVLVARLLYTLAFFVPEAHQWCCLRAYRHKYNPY---LKLQGVRRAELPSV---IMSGTSSPWPICIIDIDRSAVCMSASYQKHRILR 599
[Close]
BLAST of Zgc:100846 vs. Ensembl Celegans
Match: alfa-1 (ALS/FTD Associated gene homolog [Source:UniProtKB/TrEMBL;Acc:Q95QK5])

HSP 1 Score: 51.9878 bits (123), Expect = 1.288e-6
Identity = 47/235 (20.00%), Postives = 111/235 (47.23%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQF---SVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQ 1088
            ++ K I+S    ++V +F+F+   +    I+ + +SF+     ++  L         +  ++P ++      D D ++   T  ++ L+ +L +L++F   S+   + ++ T F+           L+ AI   L + G +++IG+D  L+  ++ TLA F+P   +  C+     ++  +   + +QG+ +  +  V     S  S  +P+ +I+++   V  S +Y  H+ ++
Sbjct:  372 LQHKMIVSPSRHLLVAAFIFSVQTKSGSTIT-YAISFLMSHLKQEWYLDRHSWFERMVGDSVPKMKASLFSEDSDDVLVRVTSELSRLLSLLSALERFPLVSLERPLMIKNTLFTDRGISISENRLLAKAISGCLQSQGHTVIIGSDHVLVARLLYTLAFFVPEAHQWCCLRAYRHKYNPY---LKLQGVRRAELPSV---IMSGTSSPWPICIIDIDRSAVCMSASYQKHRILR 599
[Close]
BLAST of Zgc:100846 vs. Ensembl Celegans
Match: alfa-1 (ALS/FTD Associated gene homolog [Source:UniProtKB/TrEMBL;Acc:Q95QK5])

HSP 1 Score: 51.9878 bits (123), Expect = 1.288e-6
Identity = 47/235 (20.00%), Postives = 111/235 (47.23%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQF---SVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQ 1088
            ++ K I+S    ++V +F+F+   +    I+ + +SF+     ++  L         +  ++P ++      D D ++   T  ++ L+ +L +L++F   S+   + ++ T F+           L+ AI   L + G +++IG+D  L+  ++ TLA F+P   +  C+     ++  +   + +QG+ +  +  V     S  S  +P+ +I+++   V  S +Y  H+ ++
Sbjct:  372 LQHKMIVSPSRHLLVAAFIFSVQTKSGSTIT-YAISFLMSHLKQEWYLDRHSWFERMVGDSVPKMKASLFSEDSDDVLVRVTSELSRLLSLLSALERFPLVSLERPLMIKNTLFTDRGISISENRLLAKAISGCLQSQGHTVIIGSDHVLVARLLYTLAFFVPEAHQWCCLRAYRHKYNPY---LKLQGVRRAELPSV---IMSGTSSPWPICIIDIDRSAVCMSASYQKHRILR 599
[Close]
BLAST of Zgc:100846 vs. Ensembl Celegans
Match: alfa-1 (ALS/FTD Associated gene homolog [Source:UniProtKB/TrEMBL;Acc:Q95QK5])

HSP 1 Score: 51.9878 bits (123), Expect = 1.297e-6
Identity = 47/235 (20.00%), Postives = 111/235 (47.23%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQF---SVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQ 1088
            ++ K I+S    ++V +F+F+   +    I+ + +SF+     ++  L         +  ++P ++      D D ++   T  ++ L+ +L +L++F   S+   + ++ T F+           L+ AI   L + G +++IG+D  L+  ++ TLA F+P   +  C+     ++  +   + +QG+ +  +  V     S  S  +P+ +I+++   V  S +Y  H+ ++
Sbjct:  369 LQHKMIVSPSRHLLVAAFIFSVQTKSGSTIT-YAISFLMSHLKQEWYLDRHSWFERMVGDSVPKMKASLFSEDSDDVLVRVTSELSRLLSLLSALERFPLVSLERPLMIKNTLFTDRGISISENRLLAKAISGCLQSQGHTVIIGSDHVLVARLLYTLAFFVPEAHQWCCLRAYRHKYNPY---LKLQGVRRAELPSV---IMSGTSSPWPICIIDIDRSAVCMSASYQKHRILR 596
[Close]
BLAST of Zgc:100846 vs. Ensembl Zebrafish
Match: C13H9orf72 (zgc:100846 [Source:ZFIN;Acc:ZDB-GENE-040801-47])

HSP 1 Score: 75.0998 bits (183), Expect = 7.968e-14
Identity = 95/377 (25.20%), Postives = 172/377 (45.62%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQ---SGNYTYHKW------MQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKI-MNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTV 1487
            +KF ++L+EK  +IV S +F+   + +K  +   LS I P       L    +    +   I   RI  +K     +I+  +  I  ++ +L S+ + SV   + L+ T  +     +    +FL  AI SHL T G S+V+G++   +N ++ TL +FL   +R+ C  L   +  F + + + VQGL KD+     + +  V+   YP T I+++   V Q      +TYH+       +  L   A                Y  +++I  D + KD      L K+F+ ++ +   G   +    + F+ L++ KA  L+   +   +K    + ++ LRN   D+  L  +GD  I++A AE+L  G++  V
Sbjct:   83 VKF-FVLAEKGVIIV-SLIFDGELKGDK--NTCALSIILPQSELSFYLPLHAVCVERLKHVIRKGRICMQKGYN--IISMLSSEIVPIMELLTSMKKHSVPEEVDLKDTVLNDDDIGDSCHEDFLHKAISSHLQTCGCSMVVGSNPEKVNKIVLTLCLFLTPAERK-CSRLCHPDGSFKYDTGLFVQGLLKDSTGSFVFPYRQVLYSPYPTTHIDVDINTVKQMPPCHEHTYHQRRYMRAELSALWKAASEDDFSSDNLINAQDSYTPDLNIFQDVMHKD-----TLVKSFIDEVFLLKPGLSLRSVYLSHFLLLLHRKALTLLRYIEDETQK--GKKPFRSLRNLKTDL-DLTVEGDLNIIMAMAEKLRAGLHSFV 444
[Close]
BLAST of Zgc:100846 vs. Ensembl Xenopus
Match: c9orf72 (chromosome 9 open reading frame 72 [Source:NCBI gene;Acc:549016])

HSP 1 Score: 80.1073 bits (196), Expect = 3.011e-15
Identity = 113/476 (23.74%), Postives = 192/476 (40.34%), Query Frame = 3 
Query:   93 YGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRI-IHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKL---------YLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            Y P+       WD   GP ++++W  +     L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       L    +    +   I   RI +H+      ++T   + I  L   L S+    V   I +  T  +     +    +FL  AI SH+ T G S+V+G+    +N M+RTL +FL   +R+ C  L   E  F + S + VQGL KD        F  V+   YP T I+++   V Q      H + Q     A L  L+     + I +         +  N++I  D + +D        K F+ ++         +      F+ +++ KA  L+   +   +K    + +K LR+   D+  L  +GD  I++A AE++ PG++
Sbjct:   22 YSPLLAATFAYWDNILGPRVRHIWSPKSDHVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQSELAFYLPLHKVCVARLTHIIRKGRIWMHKGQSITHMLTGEVIPIMEL---LSSIKSHGVPEEIDITSTVLNDDDIGDSCHGDFLINAISSHMQTCGCSVVVGSSAEKVNKMVRTLCLFLSPTERK-CSRLCRSESSFQYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDIFTVKQMPPCHEHTYNQRRYMRAELGALWKATSDEEIGMDSVIHSDETFTPNLNIFQDILHRD-----TFVKNFLDQVFQLKPNLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRSLKTDL-DLAAEGDLYIIMALAEKIKPGLH 440
[Close]
BLAST of Zgc:100846 vs. Ensembl Xenopus
Match: c9orf72 (chromosome 9 open reading frame 72 [Source:NCBI gene;Acc:549016])

HSP 1 Score: 78.1814 bits (191), Expect = 1.366e-14
Identity = 112/493 (22.72%), Postives = 196/493 (39.76%), Query Frame = 3 
Query:   93 YGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKL---------YLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            Y P+       WD   GP ++++W  +     L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W   +   + Q      ++  K  Q  +    T  +  ++ +L S+    V   I +  T  +     +    +FL  AI SH+ T G S+V+G+    +N M+RTL +FL   +R+ C  L   E  F + S + VQGL KD        F  V+   YP T I+++   V Q      H + Q     A L  L+     + I +         +  N++I  D + +D        K F+ ++         +      F+ +++ KA  L+   +   +K    + +K LR+   D+  L  +GD  I++A AE++ PG++
Sbjct:   22 YSPLLAATFAYWDNILGPRVRHIWSPKSDHVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQSELAFYLPLHKVCVARLTHIIRKGRIWMHKLVKILLQGFSNYFMLSSKQGQS-ITHMLTGEVIPIMELLSSIKSHGVPEEIDITSTVLNDDDIGDSCHGDFLINAISSHMQTCGCSVVVGSSAEKVNKMVRTLCLFLSPTERK-CSRLCRSESSFQYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDIFTVKQMPPCHEHTYNQRRYMRAELGALWKATSDEEIGMDSVIHSDETFTPNLNIFQDILHRD-----TFVKNFLDQVFQLKPNLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRSLKTDL-DLAAEGDLYIIMALAEKIKPGLH 459
[Close]
BLAST of Zgc:100846 vs. Ensembl Xenopus
Match: c9orf72 (chromosome 9 open reading frame 72 [Source:NCBI gene;Acc:549016])

HSP 1 Score: 72.0182 bits (175), Expect = 3.881e-13
Identity = 68/252 (26.98%), Postives = 115/252 (45.63%), Query Frame = 3 
Query:  756 EFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKL---------YLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            +FL  AI SH+ T G S+V+G+    +N M+RTL +FL   +R+ C  L   E  F + S + VQGL KD        F  V+   YP T I+++   V Q      H + Q     A L  L+     + I +         +  N++I  D + +D        K F+ ++         +      F+ +++ KA  L+   +   +K    + +K LR+   D+  L  +GD  I++A AE++ PG++
Sbjct:   44 DFLINAISSHMQTCGCSVVVGSSAEKVNKMVRTLCLFLSPTERK-CSRLCRSESSFQYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDIFTVKQMPPCHEHTYNQRRYMRAELGALWKATSDEEIGMDSVIHSDETFTPNLNIFQDILHRD-----TFVKNFLDQVFQLKPNLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRSLKTDL-DLAAEGDLYIIMALAEKIKPGLH 286
[Close]
BLAST of Zgc:100846 vs. Ensembl Mouse
Match: C9orf72 (C9orf72, member of C9orf72-SMCR8 complex [Source:MGI Symbol;Acc:MGI:1920455])

HSP 1 Score: 81.6481 bits (200), Expect = 7.898e-16
Identity = 118/495 (23.84%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD        F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++ +   G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-VLEGTERMEDQGQSIIPMLTGEVIPVMELLASMKSHSVPEDIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. Ensembl Mouse
Match: C9orf72 (C9orf72, member of C9orf72-SMCR8 complex [Source:MGI Symbol;Acc:MGI:1920455])

HSP 1 Score: 76.2554 bits (186), Expect = 1.310e-14
Identity = 76/290 (26.21%), Postives = 130/290 (44.83%), Query Frame = 3 
Query:  654 LIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD        F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++ +   G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   19 VMELLASMKSHSVPEDIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 303
[Close]
BLAST of Zgc:100846 vs. Ensembl Mouse
Match: C9orf72 (C9orf72, member of C9orf72-SMCR8 complex [Source:MGI Symbol;Acc:MGI:1920455])

HSP 1 Score: 65.4698 bits (158), Expect = 7.733e-11
Identity = 87/341 (25.51%), Postives = 136/341 (39.88%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQ 1055
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD        F  V+   YP T I+++   V Q
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-VLEGTERMEDQGQSIIPMLTGEVIPVMELLASMKSHSVPEDIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQ 317
[Close]
BLAST of Zgc:100846 vs. UniProt/SwissProt
Match: sp|Q96LT7|CI072_HUMAN (Guanine nucleotide exchange C9orf72 OS=Homo sapiens OX=9606 GN=C9orf72 PE=1 SV=2)

HSP 1 Score: 81.6481 bits (200), Expect = 4.310e-15
Identity = 118/495 (23.84%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD+       F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++     G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTEQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-ILEGTERMEDQGQSIIPMLTGEVIPVMELLSSMKSHSVPEEIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDSTGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFQLKPGLSLRSTFLAQFLLVLHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. UniProt/SwissProt
Match: sp|Q6DFW0|CI072_MOUSE (Guanine nucleotide exchange C9orf72 homolog OS=Mus musculus OX=10090 PE=1 SV=2)

HSP 1 Score: 81.6481 bits (200), Expect = 5.524e-15
Identity = 118/495 (23.84%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   I +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD        F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++ +   G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-VLEGTERMEDQGQSIIPMLTGEVIPVMELLASMKSHSVPEDIDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. UniProt/SwissProt
Match: sp|Q66HC3|CI072_RAT (Guanine nucleotide exchange C9orf72 homolog OS=Rattus norvegicus OX=10116 PE=2 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 1.732e-14
Identity = 117/495 (23.64%), Postives = 199/495 (40.20%), Query Frame = 3 
Query:   99 PVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYIL-GALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFP-------IKLKDKCL-----------VWQPMISNFMNQNIPYLRIIHRKSDQ-DGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGN-----YTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-ASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            P+       WD   GP ++++W  +  +  L +  I                     F+ N+ L G +L                  N ++  ID    +KF ++LSEK  +IV S +F+     ++  S + LS I P       + L   C+           +W         Q I  L    R  DQ   +I   T  +  ++ +L S+   SV   + +  T  +     +     FL  AI SHL T G S+V+G+    +N ++RTL +FL   +R+ C  L E E  F + S + VQGL KD        F  V+   YP T I+++   V Q        Y   ++M+  +  A  +     +  Q   +Y          I +D  +   L K F+ ++ +   G   +      F+ +++ KA  L+   +   +K    + +K LRN   D+  L  +GD  I++A AE++ PG++  +   P
Sbjct:   24 PLLAATFAYWDNILGPRVRHIWAPKTDQVLLSDGEI--------------------TFLANHTLNGEILR-----------------NAESGAID----VKF-FVLSEKGVIIV-SLIFDGNWNGDR--STYGLSIILPQTELSFYLPLHRVCVDRLTHIIRKGRIWMHKERQENVQKI-VLEGTERMEDQGQSIIPMLTGEVIPVMELLASMRSHSVPEDLDIADTVLNDDDIGDSCHEGFLLNAISSHLQTCGCSVVVGSSAEKVNKIVRTLCLFLTPAERK-CSRLCEAESSFKYESGLFVQGLLKDATGSFVLPFRQVMYAPYPTTHIDVDVNTVKQMPPCHEHIYNQRRYMRSEL-TAFWRATSEEDMAQDTIIYTDESFTPDLNIFQDVLHRDTLVKAFLDQVFHLKPGLSLRSTFLAQFLLILHRKALTLIKYIEDDTQK--GKKPFKSLRNLKIDL-DLTAEGDLNIIMALAEKIKPGLHSFIFGRP 467
[Close]
BLAST of Zgc:100846 vs. TrEMBL
Match: A0A2G8LCK9 (Uncharacterized protein OS=Stichopus japonicus OX=307972 GN=BSL78_05077 PE=4 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 1.676e-25
Identity = 102/396 (25.76%), Postives = 186/396 (46.97%), Query Frame = 3 
Query:  336 SYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRK---SDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEH---FNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQH-LMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKI--MNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRN---WKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTV 1487
            ++T + S+  A  I++      K +  E    IVH FLF+   + +K    F LS + P +LKD  L         +   +  LR++  K    +    I  ++  +   +  +  L  F +   I L  T F++   + +  +F+  AI  HL + G S+VIG  V  IN ++ TLA+FL   +R+  + L +      F + +D+ +QG  K + F+V+ +  S+++  YP ++++L  + V Q  +Y  H++M+H ++ + L       ++  P+  + K I  +             L + F  ++  +N  G  R+  + + F  L++ KA LL+   +     D  HR    +K    +++    L  DG+F IV+A AE+L PGIY  V
Sbjct:   86 THTLTSSDNPASAINS------KLLFLEDQDAIVHIFLFSGYQRSQKVT--FALSLVIPFQLKDWYLSVHSFCEMRLTSMVRRLRVLQEKYKSEENSPAIQAFSAKVPDFLRSITRLSNFGLPKKIELNDTVFASGQDKHLDVQFMRKAIAGHLQSCGCSVVIGNSVAEINMVLFTLALFLTPSERQYSLRLTKDSSQFPFKYEADVQLQGFLKTS-FEVEDSLLSIMASRYPTSLVDLTTLEVKQMYHYNEHEYMRHEVITKELQHTWLESKEPIPVLRFSKEIETD------------TLVENFQKEMYMLNPEGGVREAFLLH-FARLLDRKALLLIKYVE-----DETHRGKYPFKVSVRKLKADLDLTPDGNFRIVIAHAEKLQPGIYSMV 454
[Close]
BLAST of Zgc:100846 vs. TrEMBL
Match: A0A0B6ZUZ3 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF81365 PE=4 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 6.185e-18
Identity = 115/468 (24.57%), Postives = 202/468 (43.16%), Query Frame = 3 
Query:  102 VSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSD-QDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVE-LIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQ---LKCDGDFLIVLAFAEQLCPGIYCTVL 1490
            +  ++L  WD   GP L+++WYV   ++    N +     ++ + + C D                        HC                     + FK+       +I+ SF+F+A  Q    IS   ++ I P       L    +I +++ + I  LR+I  K D     + D +  +   + +L SL +  +   I L  T FS  S  K+  +FL   I SHL+TFGRS++ G  V+ +N ++ TL +F   D   LC    +   ++ +  D+ +QG  K++   ++ +   ++   YP T+I+++N  +  S +   H W   L HEAL+++L  L + Q      +   +N    +     + DL    V K+    G +R+  I + FM  +  +A  L+    + L  D    +    R  ++ + Q   L  +GD  IVLA A++L PG+Y  VL
Sbjct:   62 IDALLLCHWDNILGPKLEHVWYV-TGRSQPHTNILRFVTNQVLSGEICRD-----------------------VHCSQ-------------------VDFKFFDIPDKGVIIPSFIFSA--QGSSGISLQAIALIIPNSELTLYLHQVDLIHSWLTRVISKLRVICAKKDFATSGLADLSSWLWSFMDMLSSLQEVGLPQKIELSYTAFS--SPHKVDLDFLRQVISSHLMTFGRSVIFGKRVDRVNILVYTLGLFC-WDSERLCSRAALSGRNWPYYQDVCIQGCLKNDDDSINMSHRDLLCSRYPTTIIDVDNRSITHSSSAADHPW---LSHEALVRELEELYQGQE-GYGERPAKMNPAVSMTSESLVRDLLDN-VYKLPPDHG-KREAYICH-FMHTLQRRAFCLI----KYLEGDQQSSSTASSRVNVKKLRQDLGLALEGDLRIVLATADKLKPGLYQYVL 470
[Close]
BLAST of Zgc:100846 vs. TrEMBL
Match: V4BZ99 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_232306 PE=4 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 7.138e-18
Identity = 121/487 (24.85%), Postives = 202/487 (41.48%), Query Frame = 3 
Query:   66 SVNSTNFFPYGP---VSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNA------PNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSD-QDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELI-EKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNI--HINLDYILKDGCYLGDLCKTFVTKIMNASG-CRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKD--PNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            SV +T+   Y P   +S ++   WD   GP L ++W ++   T                         P   I+ ++ G +L+G  E C                ++D+ N I FK+ +     ++V SF+F+A        Q    + P+C   ++        L +  ++   + + I  LRI+  K+   + ++ +++  +T    +  SL +  +     L  T F       +  EFL   I SHL+TFGRSLV+G     +N +I TLA+F   D+   C  L+ E + + F  D+ VQGL K     +      ++   YP T+I++ N  V QS     HK   + +              + I L+   I  H  +  + +   Y   L    + +I   S  C  ++     F+  +N KA  L+   +    K   P     K LR   QD+  L  +GDF IV+A AE+L PGI+
Sbjct:   46 SVFTTSELKYIPNCFLSAILYCHWDNILGPRLYHVWKIENCDT-------------------------PPVDILRFLSGQILSG--EICR---------------ELDSGN-IDFKFYVMPDKDVVVSSFVFSAKLDNDLAIQSIGLVLPYCNLHLY--------LKYHQLLQLCLRRMISKLRILMNKASLSENVLNEFSAWLTMCFEMFSSLTEAGLPQQPRLSDTAFC--PLHNLEPEFLYRCITSHLMTFGRSLVVGKLAERVNLVISTLAVFNS-DRERACSRLVLEDKPWTFHHDLCVQGLIKSKNGAIVLPMREILCSQYPTTIIDVQNRDVKQSPYSQEHKVRNYEVLRD-----------ELICLHYNQIDEHDVICSMFQKAQYNSTLVSNLLEEISKLSADCGIRIAHIQQFIRYLNRKALSLIKYVETETLKGSIPLKGGLKKLR---QDL-SLTIEGDFRIVIATAEKLKPGIF 463
[Close]
BLAST of Zgc:100846 vs. TrEMBL
Match: N1PB17 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_180194 PE=4 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 9.302e-17
Identity = 118/503 (23.46%), Postives = 215/503 (42.74%), Query Frame = 3 
Query:   24 ILMLKIDKNEEFLRSVNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTI--CLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELI--EKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHL-----MHEAXXXXXXXXXXCQPI--KLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMN-----ASGCRRKLEIFNIFMELMNAKAKLLVTLA--KQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            +++ +   N E+   V+  N  P   V+ ++L  WD   GP +++LW  +     + ++++              DY+       + + G +    D+P                        I F++ L  +  +IV SF+F A   +E  +    LS +   + + +CL  Q ++S++M + I +LR+   K   D  +  +T  +   I +L SL++  +   I  C   T F+     +    FL  AI SHLI+   S+V+G + N +N MI TL +FL   +R+ C   +    +   +S D+ +QG  +    +++ +   V     P T+I+L    V  S     H  +Q+      ++E    +       + I  K+ L++ H  L     +  +  D  +T VT +           ++     + F+  ++ KA  L+     +    ++P   + K LR   QD+  LK  GDF IVLA AE+L PGI+
Sbjct:   23 VVLTESATNHEY--PVHVINDSPNSLVARIVLCYWDNIMGPCVRHLWNSEAQGMHVPQSAL--------------DYIA-----THTLSGEITRDEDDPT-----------------------IDFRFFLIRESNLIVTSFVFGAIGGNESVVH--SLSIVVRQEHRQRCLELQALMSSWMLRGIHHLRVYLEKETGDTSMDRFTPYLMQFIQMLTSLNESGLPGRISDCDIDTAFNPDCGCQFDGHFLCRAISSHLISARCSVVVGDNPNKVNKMIATLGLFLDSAERQ-CSRFVLYGNKSCPYSPDLFLQGFLQSASGELNTSLKDVHLSQRPTTLIDLTTQEVKFSCQPHQHLALQYRAVKRKLNELWTGRADNTFPFRSIGAKIILES-HFYLLPFFSEMFHTFDEPETLVTNLFEEWKLLPPNIKQHEAYISQFISGLDRKAMTLIRFVECETNCGQNPLKISVKKLR---QDL-SLKVPGDFSIVLATAEKLKPGIF 473
[Close]
BLAST of Zgc:100846 vs. TrEMBL
Match: A0A1S3HDQ0 (guanine nucleotide exchange C9orf72 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106153716 PE=4 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 1.181e-16
Identity = 122/483 (25.26%), Postives = 201/483 (41.61%), Query Frame = 3 
Query:   69 VNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREF-LSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGL------CKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQH--LMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVL 1490
            V+S+N      +  V+L  WD   GP + ++W                        + CN+ VE  K++  Y     LNG  E C           +     ID     KF Y++S + ++ V + +F A  +     S  CLS +       K + WQ  +  ++ + I  LR++  K + D  I      I   + +L+SL    + + I L  TYF     E   ++F L  +I SHL+T GRS+V GT  + IN M+ TLA+F    +R+       + ++ +  D+ VQG        + ++ D       +    YP ++I++    V Q+     H   +H  L  E              +K   KNI  NL Y         +L   F+ ++  A     +L    +F+  +  KA +L+  A+  +  D      K    +++    L+ +GDF IVLA AE+L PGIY  +L
Sbjct:  100 VSSSNL-----IQAVVLSLWDNIVGPRILHVW----------------------KGEACNETVETFKYLSIYT----LNG--EICR----------DLTCGGIDT----KF-YVMSRR-KLCVLALIFGAKGKCGP--SVHCLSVVMSSNDLQKYVTWQRTLHAWLKRRIAVLRVLMEKDEYDKGIHFLNASINKTMRMLQSLQLDGLPSCIKLEDTYFYN---EDSSKDFLLRKSITSHLMTCGRSVVTGTVDSEINKMVSTLALFNTSAERQCSRFCSHERNWPYHHDLCVQGWLPPSYNLRQSVLD-KIPLGEMQCAEYPTSIIDVKTHEVRQTLPVNEHHTRRHDFLSQEVTHPYSK-----HDVKYPEKNILDNLQYP-------ENLVHRFMKELF-AIPVGLRLSFIQLFIRTIERKALVLIKSAE--VDSDQGRSAPKTNPRKLRQDLGLQLEGDFRIVLAMAEKLKPGIYTYLL 512
[Close]
BLAST of Zgc:100846 vs. Ensembl Cavefish
Match: zgc:100846 (C9orf72-SMCR8 complex subunit [Source:NCBI gene;Acc:103042017])

HSP 1 Score: 70.8626 bits (172), Expect = 1.335e-12
Identity = 99/381 (25.98%), Postives = 176/381 (46.19%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSD---QDG--LITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSG---NYTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDY-ILKDGCYLGDLCKTFVTKI-MNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            +KF ++L+EK  +IV S +F+   + +K  +   LS I P   + +   + P+ S  + +    L+ I RK     Q G  +I   T  I  ++ +L S+   SV   + ++ T  +     +    +FL  AI SHL T G S+V+G++   +N ++ TL++FL   +R+ C  L   +  F + + + VQGL KD+       +  V+   YP T I+++   V Q      + YH+        + L K    +   P  L         D  I +D  +   L K+F+ ++ +   G   +    + F+ L++ KA  L+   +   +K    + ++ LRN   D+  L  +GD  IV+A AE+L  G++  V   P
Sbjct:   83 VKF-FVLAEKGVIIV-SLIFDGELKGDK--NTCALSIILP---QSELNFYLPLHSVCVER----LKHIVRKGRICMQKGYSIIAMLTSEIVPIMELLSSMKTHSVPEEVDIKDTLLNDDDIGDSCHEDFLHKAISSHLQTCGCSIVVGSNPEKVNKIVLTLSLFLTPTERK-CSRLCRADGSFKYDTGLFVQGLLKDSTGSFVLPYRQVLYSPYPTTHIDVDINTVKQMPPCHEHMYHQRRYMRSELSALWKAASEDNISPDNLINSQDSFTPDLNIFQDVMHKDTLVKSFIYEVFLLKPGLSLRSVYLSHFLLLLHRKALTLLRYIEDETQK--GKKPFRSLRNLKTDL-DLTVEGDLNIVMAMAEKLRAGLHYFVFGKP 448
[Close]
BLAST of Zgc:100846 vs. Ensembl Cavefish
Match: zgc:100846 (C9orf72-SMCR8 complex subunit [Source:NCBI gene;Acc:103042017])

HSP 1 Score: 58.5362 bits (140), Expect = 1.002e-8
Identity = 66/239 (27.62%), Postives = 116/239 (48.54%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSD---QDG--LITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQ 1088
            +KF ++L+EK  +IV S +F+   + +K  +   LS I P   + +   + P+ S  + +    L+ I RK     Q G  +I   T  I  ++ +L S+   SV   + ++ T  +     +    +FL  AI SHL T G S+V+G++   +N ++ TL++FL   +R+ C  L   +  F + + + VQGL KD+       +  V+   YP T I+++   V Q      H + Q
Sbjct:   83 VKF-FVLAEKGVIIV-SLIFDGELKGDK--NTCALSIILP---QSELNFYLPLHSVCVER----LKHIVRKGRICMQKGYSIIAMLTSEIVPIMELLSSMKTHSVPEEVDIKDTLLNDDDIGDSCHEDFLHKAISSHLQTCGCSIVVGSNPEKVNKIVLTLSLFLTPTERK-CSRLCRADGSFKYDTGLFVQGLLKDSTGSFVLPYRQVLYSPYPTTHIDVDINTVKQMPPCHEHMYHQ 309
[Close]
BLAST of Zgc:100846 vs. Ensembl Sea Lamprey
Match: zgc:100846 (C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;Acc:HGNC:28337])

HSP 1 Score: 90.8929 bits (224), Expect = 1.094e-19
Identity = 87/323 (26.93%), Postives = 157/323 (48.61%), Query Frame = 3 
Query:  531 CLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFL-PLDKRELCVELIEKEHFN-FSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNN-MRVLQSGNYTYHKWMQH--LMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRN--QIQDVCQLKCDGDFLIVLAFAEQLCPGIY 1478
            C+V +P+I   +N  + +++      D D ++   T  +T +  +  SL+   V ++I L+ TYF  +  E+ +R  LS+ + SHL T G S+VIG+D   +N M++TL +FL P ++R  C  L + E  + +   ++VQGL KD    +   F SVV    P ++++++    V Q+     H + QH  L  E +       + C P  +       +++Y  ++      L  TF+ ++       R L+    F+ L+  KA     LA     +D   +  K L++  +++    L   GD  +V+A AEQ+ PG++
Sbjct:  156 CIVARPVI---LNATLMFVQ------DSDNIVQFLTGELTSIAKLFVSLNSHGVPDSISLKDTYFEDNPEEE-KRNILSSVVRSHLQTCGCSIVIGSDPREVNKMVKTLCLFLSPAERR--CSRLADPEAKDKYEYGLVVQGLLKDKDGILTLPFRSVVLAPMPSSLVDVDRPYSVFQTPPKHVHVFRQHKLLRSELVRYWSDPTQLCAPSPIQ------DINY-FQEVPAPDTLVSTFINEVFMVDVGER-LQFLARFVLLLQRKA-----LALLFHIEDETQQGKKPLQSLGKVKKELDLTDKGDLSVVMATAEQMRPGVH 453
[Close]
BLAST of Zgc:100846 vs. Ensembl Nematostella
Match: EDO36091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJN8])

HSP 1 Score: 76.6406 bits (187), Expect = 9.577e-15
Identity = 106/511 (20.74%), Postives = 203/511 (39.73%), Query Frame = 3 
Query:   96 GPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGG---DEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLI----TDYTVVITYL-------IGVL-RSLDQFSVSNT----ICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFN-FSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRK--------DPNHRNWKF-----LRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECPSEKISDLATM 1529
            GP   ++L  WD   GP L+++W                   E +N + C          V Y++   LNG    D P                     +N++  K  + ++  ++ HSF+F   +     IS   LS + P       L    ++ + +   I  LR++  K     ++       + V+T+L       I VL  +  +FS+       + +  T F           FL   I SHL TFG ++VIG  ++ +N MI +LA+FL  ++R+     ++    + + +D+ +QG+ KD   +       V++  YP T+++++   V ++  Y  H  ++    +  L  ++   +  P+   +   H   D        +G L + F+  +             N+     + +A  + T  + L+RK        +   +  +       + Q++   QL  + DF IVLA AE+  PG+Y  ++  P   ++ + T+
Sbjct:   62 GPFMGIVLSYWDNILGPRLRHVWR---------------GGGEEKNQENC----------VKYVVSRTLNGELLRDAP---------------------ENVVDTKLFVIKEKGIVCHSFIFTGRDSSGSNIS--ALSLMLPHIDMAGYLPLVELVEDRVKILIAKLRVLQTKDKNQNILWWALGSVSRVLTWLPLEGGHFIEVLLYACYKFSLVTFFNFFLQINNTVFGADHNVVFDPVFLRRVITSHLQTFGSTMVIGQSISRVNLMINSLALFLSSNERQKSRYAVDGADTDVYDTDLYLQGVIKDGDGNFTLPVKGVITSIYPTTLVDVDTCDVKKTYPYHEHSVIRKEFLDLELALMWEGHEGAPVYPSIGLFHPAED--------IGLLVQIFINDM-------------NVLPFAPDVRAGFVETFRRLLVRKTLALIKYVEARSKRGRIALEYAAKRQLRHDLQLNTEADFGIVLACAEKHKPGLYTFLMGDPRHAVARVQTI 503
[Close]
BLAST of Zgc:100846 vs. Ensembl Medaka
Match: zgc:100846 (C9orf72-SMCR8 complex subunit [Source:NCBI gene;Acc:101166020])

HSP 1 Score: 82.4185 bits (202), Expect = 2.524e-16
Identity = 100/375 (26.67%), Postives = 179/375 (47.73%), Query Frame = 3 
Query:  393 IKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSY-EKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKE-HFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVI--NLNNMRVLQSGNYTYHKWMQHLMHE-AXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKI-MNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECP 1499
            +KF ++L+EK  +IV S +F+   + +K  +   LS I P       L    +  + +   +   RI  +K     +I   +  I  ++ +L S+   SV   I ++ T  +     +    +FL  AI SHL T G SLV+G++   +N ++RTL +FL   +R+ C  L   + HF + + + VQGL KD+       +  V+   YP T I  ++N ++ +   +   +K  Q++  E + L K    E   P  +   +   +L+ I  D  +   L K+F+ ++ M   G   +    + F+ L++ KA  L+   +   +K    + ++ LRN   D+  LK +GD  I++AFAE+L  G++  V   P
Sbjct:   83 VKF-FVLAEKGVIIV-SLIFDGELKGDK--NTCALSIILPQTELSFYLPLHAVCVDRLKHAVRKGRICMQKGFN--IIDVLSSEIDPIMKLLASMKSHSVPEDIDIKDTVLNDDDIGDSCHEDFLHKAISSHLQTCGCSLVVGSNPEKVNKIVRTLCLFLTPAERK-CSRLCRADSHFKYDTGLFVQGLLKDSTGSCVLPYRQVLYSPYPTTHIDVDINTVKQMPPCHEHTYKQRQYMRLELSSLWKAESEEDISPDNIIHTSETPDLN-IFHDVMHKDTLVKSFIDEVFMLKPGLSLRSTYLSQFLLLLHRKALTLLKYIEDDTQK--GKKPFRSLRNLKTDL-DLKEEGDLNIIMAFAEKLKSGLHSFVFWKP 446
[Close]
BLAST of Zgc:100846 vs. Planmine SMEST
Match: SMESG000031124.1 (SMESG000031124.1)

HSP 1 Score: 1010.75 bits (2612), Expect = 0.000e+0
Identity = 500/500 (100.00%), Postives = 500/500 (100.00%), Query Frame = 3 
Query:   30 MLKIDKNEEFLRSVNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEAXXXXXXXXXXCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECPSEKISDLATM 1529
            MLKIDKNEEFLRSVNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEALLKKLFLLEKCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECPSEKISDLATM
Sbjct:    1 MLKIDKNEEFLRSVNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKSKTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHCDDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKFISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLITDYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIMSHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFSSDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHKWMQHLMHEALLKKLFLLEKCQPIKLYLKNIHINLDYILKDGCYLGDLCKTFVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWKFLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECPSEKISDLATM 500
The following BLAST results are available for this feature:
BLAST of Zgc:100846 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
C9orf728.974e-1623.84C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
C9orf728.974e-1623.84C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
C9orf726.731e-1423.32C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
C9orf722.894e-1125.51C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
C9orf727.205e-1125.51C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
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BLAST of Zgc:100846 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
alfa-11.288e-620.00ALS/FTD Associated gene homolog [Source:UniProtKB... [more]
alfa-11.288e-620.00ALS/FTD Associated gene homolog [Source:UniProtKB... [more]
alfa-11.288e-620.00ALS/FTD Associated gene homolog [Source:UniProtKB... [more]
alfa-11.297e-620.00ALS/FTD Associated gene homolog [Source:UniProtKB... [more]
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BLAST of Zgc:100846 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Zgc:100846 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C13H9orf727.968e-1425.20zgc:100846 [Source:ZFIN;Acc:ZDB-GENE-040801-47][more]
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BLAST of Zgc:100846 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
c9orf723.011e-1523.74chromosome 9 open reading frame 72 [Source:NCBI ge... [more]
c9orf721.366e-1422.72chromosome 9 open reading frame 72 [Source:NCBI ge... [more]
c9orf723.881e-1326.98chromosome 9 open reading frame 72 [Source:NCBI ge... [more]
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BLAST of Zgc:100846 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
C9orf727.898e-1623.84C9orf72, member of C9orf72-SMCR8 complex [Source:M... [more]
C9orf721.310e-1426.21C9orf72, member of C9orf72-SMCR8 complex [Source:M... [more]
C9orf727.733e-1125.51C9orf72, member of C9orf72-SMCR8 complex [Source:M... [more]
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BLAST of Zgc:100846 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|Q96LT7|CI072_HUMAN4.310e-1523.84Guanine nucleotide exchange C9orf72 OS=Homo sapien... [more]
sp|Q6DFW0|CI072_MOUSE5.524e-1523.84Guanine nucleotide exchange C9orf72 homolog OS=Mus... [more]
sp|Q66HC3|CI072_RAT1.732e-1423.64Guanine nucleotide exchange C9orf72 homolog OS=Rat... [more]
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BLAST of Zgc:100846 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2G8LCK91.676e-2525.76Uncharacterized protein OS=Stichopus japonicus OX=... [more]
A0A0B6ZUZ36.185e-1824.57Uncharacterized protein OS=Arion vulgaris OX=10286... [more]
V4BZ997.138e-1824.85Uncharacterized protein OS=Lottia gigantea OX=2251... [more]
N1PB179.302e-1723.46Uncharacterized protein OS=Capitella teleta OX=283... [more]
A0A1S3HDQ01.181e-1625.26guanine nucleotide exchange C9orf72 isoform X1 OS=... [more]
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BLAST of Zgc:100846 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
zgc:1008461.335e-1225.98C9orf72-SMCR8 complex subunit [Source:NCBI gene;Ac... [more]
zgc:1008461.002e-827.62C9orf72-SMCR8 complex subunit [Source:NCBI gene;Ac... [more]
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BLAST of Zgc:100846 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zgc:1008461.094e-1926.93C9orf72-SMCR8 complex subunit [Source:HGNC Symbol;... [more]
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BLAST of Zgc:100846 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Zgc:100846 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO360919.577e-1520.74Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Zgc:100846 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zgc:1008462.524e-1626.67C9orf72-SMCR8 complex subunit [Source:NCBI gene;Ac... [more]
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BLAST of Zgc:100846 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000031124.10.000e+0100.00SMESG000031124.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001805 ID=SMED30001805|Name=Zgc:100846|organism=Schmidtea mediterranea sexual|type=transcript|length=1814bp
GTAAAATTTGACCTTAATTTTTTATTTTAATGTTGAAAATAGATAAAAAT
GAAGAGTTTTTAAGATCTGTTAATTCTACAAATTTCTTTCCTTATGGTCC
AGTTTCATTTGTTATTCTAGGTGCATGGGATACTAGAAGAGGTCCACTGT
TAAAAAATTTGTGGTATGTGCAAAAATCTAAAACTGATTTACAAGAAAAT
TCAATAGAATTAAATATTCAAGAAATTGAAAATAACAAATATTGCAATGA
TTATGTCGAACCTACTAAATTTATTGTTAATTATATTTTGGGAGCATTGC
TAAATGGGGGTGATGAACCATGCCATTGTGATGACAGTTATACTACATCA
TATTCAAATCAAAAAGCAGACAAAATAGACGCTGATAATTTAATAAAATT
TAAATATATTCTTTCTGAAAAGCATCAAATGATTGTGCATAGTTTTCTTT
TTAATGCTCCAAATCAAGATGAAAAGTTTATTAGTCCATTTTGTTTAAGT
TTCATTTTCCCAATAAAATTGAAAGACAAATGTTTGGTCTGGCAACCAAT
GATAAGCAATTTTATGAATCAGAATATTCCTTATCTGCGAATAATTCACA
GAAAGAGTGACCAAGATGGACTAATAACTGACTATACGGTTGTCATAACG
TATTTGATAGGAGTTTTACGAAGCCTCGACCAGTTCTCGGTATCAAACAC
GATTTGTCTAAGGAAAACGTATTTTTCGACAAGTTCCTATGAAAAGATTC
GAAGAGAATTCCTCAGTACTGCTATTATGTCACATCTCATAACTTTCGGC
CGATCATTAGTTATAGGAACTGACGTTAATTTAATAAATACGATGATTAG
AACACTGGCTATATTTTTGCCTCTGGATAAAAGAGAATTATGTGTAGAAC
TCATTGAAAAAGAGCATTTCAATTTTTCAAGCGATATTATGGTCCAGGGA
CTATGTAAGGATAATATTTTTGATGTTGATTATACATTTTGGTCAGTTGT
CAGCGGTTCTTATCCTCTAACTGTTATAAATCTGAATAATATGAGAGTGC
TCCAAAGTGGCAATTATACATATCATAAATGGATGCAACATTTAATGCAT
GAGGCTCTGCTGAAGAAATTATTTTTATTAGAAAAATGCCAACCAATTAA
ACTTTATTTGAAAAATATTCACATCAATTTGGATTATATTTTGAAAGATG
GTTGCTACCTTGGAGATCTCTGTAAAACATTTGTCACAAAGATTATGAAT
GCTTCTGGATGTCGAAGGAAACTTGAAATATTTAATATTTTTATGGAATT
GATGAATGCTAAAGCAAAATTACTTGTTACTTTAGCAAAACAACTACTCA
GAAAAGATCCAAATCATAGAAATTGGAAATTTCTTCGCAATCAAATTCAA
GACGTATGCCAGTTAAAATGCGACGGAGATTTTCTAATTGTGTTAGCCTT
TGCTGAGCAGCTTTGTCCGGGAATATATTGCACTGTGCTCGAGTGTCCAA
GCGAAAAAATAAGTGATCTCGCTACCATGTTTAATCATTTGTAATTTTAC
CTACTTTTTACTTATTAAAATTTGGTGAAGAATTATGATATTTCTATTGT
TTATTTTTACTAATGTCATAGTTTAGTTTTTTAATTTATATATTTTCTTT
AACAAGTTTATATGTCCTCGTGGTGGCCTTAATTTCATTGTTTCATGAGT
TGAGCGTGCTTTTTATTATGCCTCGCCTTTTTGTCGAAATTGGATTTTTG
TCTCTTTCGTCTATGTTTTTTGAAAACTTTTGAAATCGAAGTTTTCATTT
ATTATTATATTCAC
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protein sequence of SMED30001805-orf-1

>SMED30001805-orf-1 ID=SMED30001805-orf-1|Name=SMED30001805-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=505bp
MLKIDKNEEFLRSVNSTNFFPYGPVSFVILGAWDTRRGPLLKNLWYVQKS
KTDLQENSIELNIQEIENNKYCNDYVEPTKFIVNYILGALLNGGDEPCHC
DDSYTTSYSNQKADKIDADNLIKFKYILSEKHQMIVHSFLFNAPNQDEKF
ISPFCLSFIFPIKLKDKCLVWQPMISNFMNQNIPYLRIIHRKSDQDGLIT
DYTVVITYLIGVLRSLDQFSVSNTICLRKTYFSTSSYEKIRREFLSTAIM
SHLITFGRSLVIGTDVNLINTMIRTLAIFLPLDKRELCVELIEKEHFNFS
SDIMVQGLCKDNIFDVDYTFWSVVSGSYPLTVINLNNMRVLQSGNYTYHK
WMQHLMHEALLKKLFLLEKCQPIKLYLKNIHINLDYILKDGCYLGDLCKT
FVTKIMNASGCRRKLEIFNIFMELMNAKAKLLVTLAKQLLRKDPNHRNWK
FLRNQIQDVCQLKCDGDFLIVLAFAEQLCPGIYCTVLECPSEKISDLATM
FNHL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0001966thigmotaxis
GO:0021952central nervous system projection neuron axonogenesis
GO:0036268swimming
GO:0036269swimming behavior
GO:0061564axon development
GO:0006897endocytosis
GO:0006914autophagy
Vocabulary: molecular function
TermDefinition
GO:0005085guanyl-nucleotide exchange factor activity
GO:0017137Rab GTPase binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR027819C9orf72
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005615extracellular space
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005764lysosome
GO:0005768endosome
GO:0005776autophagosome
GO:0031410cytoplasmic vesicle
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR027819Guanine nucleotide exchange C9orf72PFAMPF15019C9orf72-likecoord: 115..349
e-value: 1.5E-36
score: 126.2
IPR027819Guanine nucleotide exchange C9orf72PANTHERPTHR31855FAMILY NOT NAMEDcoord: 21..490
IPR027819Guanine nucleotide exchange C9orf72PROSITEPS51835DENN_C9ORF72coord: 23..487
score: 39.187