NME/NM23 nucleoside diphosphate kinase 1

Overview


Name	NME/NM23 nucleoside diphosphate kinase 1 (AKG62119.1)
Smed ID	SMED30001801
Length (bp)	663

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of NME/NM23 nucleoside diphosphate kinase 1 (SMED30001801) t-SNE clustered cells

Violin plots show distribution of expression levels for NME/NM23 nucleoside diphosphate kinase 1 (SMED30001801) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of NME/NM23 nucleoside diphosphate kinase 1 (SMED30001801) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for NME/NM23 nucleoside diphosphate kinase 1 (SMED30001801) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001801

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30001801	SMESG000008082.1	dd_Smed_v4_1096_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30001801	SMESG000029692.1 SMESG000013977.1 SMESG000008082.1 SMESG000002488.1	Contig36634	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30001801	SMESG000029692.1 SMESG000013977.1 SMESG000008082.1 SMESG000002488.1	Contig36634	uc_Smed_v2	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
Match: NME1 (NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849])

HSP 1 Score: 203.371 bits (516), Expect = 1.395e-66
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK M+  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF+P+E+ DY  C + W+ E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
Match: NME1 (NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849])

HSP 1 Score: 203.371 bits (516), Expect = 3.364e-66
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK M+  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF+P+E+ DY  C + W+ E
Sbjct:   30 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 177

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
Match: NME1 (NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849])

HSP 1 Score: 203.371 bits (516), Expect = 3.364e-66
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK M+  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF+P+E+ DY  C + W+ E
Sbjct:   30 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 177

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
Match: NME2 (NME/NM23 nucleoside diphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:7850])

HSP 1 Score: 202.216 bits (513), Expect = 4.847e-66
Identity = 90/148 (60.81%), Postives = 114/148 (77.03%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+A+K ++  ++ L+ HY DLKD+PFF  L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV  A++EISLWF P+E+ DYK C   WV E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152

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Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+A+K ++  ++ L+ HY DLKD+PFF  L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV  A++EISLWF P+E+ DYK C   WV E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Celegans
Match: ndk-1 (Nucleoside diphosphate kinase [Source:UniProtKB/TrEMBL;Acc:Q93576])

HSP 1 Score: 203.371 bits (516), Expect = 6.204e-67
Identity = 92/138 (66.67%), Postives = 107/138 (77.54%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDY 472
            E+++I +KPDGV RGLVG II RFE+RG+KL+ALK M   K  LE HYQDLKDKPFF  LIEYM SGPVV M+WQG + VK GR++LGAT P+ S PGTIRGDFC   GRNI HGSD+VD A REI+ WF  +EI DY
Sbjct:    5 ERTFIAIKPDGVHRGLVGKIIARFEERGYKLVALKQMTASKAHLEVHYQDLKDKPFFPSLIEYMSSGPVVAMVWQGLDVVKQGRSMLGATNPLASAPGTIRGDFCIQTGRNICHGSDAVDSANREIAHWFKQEEINDY 142

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Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDY 472
            E+++I +KPDGV RGLVG II RFE+RG+KL+ALK M   K  LE HYQDLKDKPFF  LIEYM SGPVV M+WQG + VK GR++LGAT P+ S PGTIRGDFC   GRNI HGSD+VD A REI+ WF  +EI DY
Sbjct:    5 ERTFIAIKPDGVHRGLVGKIIARFEERGYKLVALKQMTASKAHLEVHYQDLKDKPFFPSLIEYMSSGPVVAMVWQGLDVVKQGRSMLGATNPLASAPGTIRGDFCIQTGRNICHGSDAVDSANREIAHWFKQEEINDY 142

[Close]

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDY 472
            E+++I +KPDGV RGLVG II RFE+RG+KL+ALK M   K  LE HYQDLKDKPFF  LIEYM SGPVV M+WQG + VK GR++LGAT P+ S PGTIRGDFC   GRNI HGSD+VD A REI+ WF  +EI DY
Sbjct:    5 ERTFIAIKPDGVHRGLVGKIIARFEERGYKLVALKQMTASKAHLEVHYQDLKDKPFFPSLIEYMSSGPVVAMVWQGLDVVKQGRSMLGATNPLASAPGTIRGDFCIQTGRNICHGSDAVDSANREIAHWFKQEEINDY 142

[Close]

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDY 472
            E+++I +KPDGV RGLVG II RFE+RG+KL+ALK M   K  LE HYQDLKDKPFF  LIEYM SGPVV M+WQG + VK GR++LGAT P+ S PGTIRGDFC   GRNI HGSD+VD A REI+ WF  +EI DY
Sbjct:    5 ERTFIAIKPDGVHRGLVGKIIARFEERGYKLVALKQMTASKAHLEVHYQDLKDKPFFPSLIEYMSSGPVVAMVWQGLDVVKQGRSMLGATNPLASAPGTIRGDFCIQTGRNICHGSDAVDSANREIAHWFKQEEINDY 142

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Match: awd (gene:FBgn0000150 transcript:FBtr0346150)

HSP 1 Score: 202.216 bits (513), Expect = 3.997e-66
Identity = 92/155 (59.35%), Postives = 115/155 (74.19%), Query Frame = 2

Query:   38 SIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            + M   +E+++IMVKPDGVQRGLVG II RFEQ+GFKL+ALK     K+LLE HY DL  +PFF  L+ YM SGPVV M+W+G   VK GR +LGAT P DSLPGTIRGDFC   GRNI+HGSD+V+ A++EI+LWFN KE+  +    + W+ E
Sbjct:   14 ATMAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE 168

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Match: awd (gene:FBgn0000150 transcript:FBtr0339146)

HSP 1 Score: 202.216 bits (513), Expect = 3.997e-66
Identity = 92/155 (59.35%), Postives = 115/155 (74.19%), Query Frame = 2

Query:   38 SIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            + M   +E+++IMVKPDGVQRGLVG II RFEQ+GFKL+ALK     K+LLE HY DL  +PFF  L+ YM SGPVV M+W+G   VK GR +LGAT P DSLPGTIRGDFC   GRNI+HGSD+V+ A++EI+LWFN KE+  +    + W+ E
Sbjct:   14 ATMAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE 168

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Match: awd (gene:FBgn0000150 transcript:FBtr0346611)

HSP 1 Score: 200.675 bits (509), Expect = 1.003e-65
Identity = 92/153 (60.13%), Postives = 114/153 (74.51%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M   +E+++IMVKPDGVQRGLVG II RFEQ+GFKL+ALK     K+LLE HY DL  +PFF  L+ YM SGPVV M+W+G   VK GR +LGAT P DSLPGTIRGDFC   GRNI+HGSD+V+ A++EI+LWFN KE+  +    + W+ E
Sbjct:    1 MAANKERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYMNSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALWFNEKELVTWTPAAKDWIYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Match: nmdyn-D6 (gene:FBgn0030573 transcript:FBtr0073933)

HSP 1 Score: 64.6994 bits (156), Expect = 6.045e-13
Identity = 43/133 (32.33%), Postives = 64/133 (48.12%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGAT---RPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            E +  ++KP  ++       I     + F ++  K +   K+L E  Y + K K F+ +L  +M SGP   +I Q    ++  R+LLG T   R + S P  IR  +     RN  HGSDS   A REIS+ F
Sbjct:    2 EITLALIKPHVLRNTYAMQQIRALISQNFTILDQKEVCITKELSERFYAEHKGKFFYHRLTSFMNSGPSYALILQSETCIQKWRSLLGPTKVFRAVYSDPNCIRALYGISDTRNACHGSDSEASALREISILF 134

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Match: nmdyn-D7 (gene:FBgn0028997 transcript:FBtr0082083)

HSP 1 Score: 49.2914 bits (116), Expect = 9.139e-7
Identity = 36/141 (25.53%), Postives = 63/141 (44.68%), Query Frame = 2

Query:   50 VYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKD-KPFFSKLIEYMLSGPVVCM-IWQGFEAVKIGRALLGATRPIDS------LPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            V++  +  ++KP  ++ GL+G II      GF+L A++M+   +   E  Y+  +   P +  ++  + SG  +CM I       K  R       P+D        P T+R  F +   +N VH +D  D +  E+   F
Sbjct:  243 VFKNTTLAIIKPHSIKDGLLGDIISEILSNGFRLTAMRMILMARINCEEFYEVYRGVVPEYIPMVAQLASGVCMCMEIACADPEKKTDREFRNFCGPMDPEIAKLLRPHTLRAKFGKSKVQNAVHCTDLPDDSNLELQYMF 383

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Zebrafish
Match: nme2a (NME/NM23 nucleoside diphosphate kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-7656])

HSP 1 Score: 210.305 bits (534), Expect = 2.063e-69
Identity = 92/152 (60.53%), Postives = 115/152 (75.66%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQ 499
            M   +E+++I +KPDGVQRGLVG II RFEQ+GFKL+A+K+++ D+ LL  HY DLKD+PFF  L+ YM +GPVV M+W+GF  +K GR +LG T PIDS PGTIRGDFC   GRNI+HGSDSV+ A  EI+LWF P EI DY  C E W+ 
Sbjct:    1 MSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQESWIN 152

[Close]

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQ 499
            M   +E+++I +KPDGVQRGLVG II RFEQ+GFKL+A+K+++ D+ LL  HY DLKD+PFF  L+ YM +GPVV M+W+GF  +K GR +LG T PIDS PGTIRGDFC   GRNI+HGSDSV+ A  EI+LWF P EI DY  C E W+ 
Sbjct:    1 MSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQESWIN 152

[Close]

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQ 499
            M   +E+++I +KPDGVQRGLVG II RFEQ+GFKL+A+K+++ D+ LL  HY DLKD+PFF  L+ YM +GPVV M+W+GF  +K GR +LG T PIDS PGTIRGDFC   GRNI+HGSDSV+ A  EI+LWF P EI DY  C E W+ 
Sbjct:    1 MSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQESWIN 152

[Close]

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQ 499
            M   +E+++I +KPDGVQRGLVG II RFEQ+GFKL+A+K+++ D+ LL  HY DLKD+PFF  L+ YM +GPVV M+W+GF  +K GR +LG T PIDS PGTIRGDFC   GRNI+HGSDSV+ A  EI+LWF P EI DY  C E W+ 
Sbjct:    1 MSGNEERTFIAIKPDGVQRGLVGEIIKRFEQKGFKLVAMKLIQADEDLLRQHYSDLKDRPFFPGLVSYMSAGPVVAMVWEGFNVIKTGRVMLGETNPIDSKPGTIRGDFCVQVGRNIIHGSDSVESANTEINLWFKPDEICDYTKCQESWIN 152

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Zebrafish
Match: nme2b.1 (NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-000210-32])

HSP 1 Score: 200.29 bits (508), Expect = 1.676e-65
Identity = 88/153 (57.52%), Postives = 114/153 (74.51%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M    E+++I VKPDGVQRGL+G II RFEQ+GF+L+A+K ++  + LL+ HY DLKD+PF+  L++YM SGPV+ M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSVD A  EISLWF P+E+  +K C + W+ E
Sbjct:    1 MSAKTERTFIAVKPDGVQRGLMGEIIKRFEQKGFRLVAMKFLQASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIEVGRNIIHGSDSVDSANTEISLWFKPEELVSFKSCAQQWIYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Match: c1orf112 (chromosome 1 open reading frame 112 [Source:Xenbase;Acc:XB-GENE-5952633])

HSP 1 Score: 204.527 bits (519), Expect = 2.787e-66
Identity = 91/160 (56.88%), Postives = 118/160 (73.75%), Query Frame = 2

Query:   23 SLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            S RD  +M   +E+++I +KPDGVQRGL+G II RFEQ+GF L+A+K ++  K LL+ HY DLKD+PF+  L++YM SGPV+ M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A +EI+LWF  KE+ +YK C   WV E
Sbjct:   44 SRRDSELMAANKERTFIAIKPDGVQRGLMGEIIKRFEQKGFYLVAMKFVQASKDLLKQHYIDLKDRPFYPGLVDYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESANKEIALWFEDKELVEYKCCAHEWVYE 203

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Match: c1orf112 (chromosome 1 open reading frame 112 [Source:Xenbase;Acc:XB-GENE-5952633])

HSP 1 Score: 197.978 bits (502), Expect = 2.098e-64
Identity = 88/153 (57.52%), Postives = 114/153 (74.51%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M   +E+++I +KPDGVQRGL+G II RFEQ+GF L+A+K ++  K LL+ HY DLKD+PF+  L++YM SGPV+ M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A +EI+LWF  KE+ +YK C   WV E
Sbjct:    1 MAANKERTFIAIKPDGVQRGLMGEIIKRFEQKGFYLVAMKFVQASKDLLKQHYIDLKDRPFYPGLVDYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESANKEIALWFEDKELVEYKCCAHEWVYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Match: sox8 (SRY-box 8 [Source:Xenbase;Acc:XB-GENE-480865])

HSP 1 Score: 182.185 bits (461), Expect = 6.045e-58
Identity = 78/148 (52.70%), Postives = 111/148 (75.00%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E++++ +KPDG QR L+G II RFE++GF L+A+K+M+  ++LL+ HY  L+DKPF+ +L++YM SGPVV M+WQG + VK  R ++G T P  SLPGTIRGDFC   GRN++HGSDS + A+REI+LWF P E+  ++   E W+ E
Sbjct:   22 ERTFLAIKPDGYQRRLIGEIIRRFEKKGFHLVAMKIMQASEQLLKQHYIALQDKPFYDRLVKYMGSGPVVAMVWQGLDVVKTARLMIGETNPAHSLPGTIRGDFCVDVGRNVIHGSDSRESAQREIALWFQPDELVCWQDSTESWIYE 169

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Match: sox8 (SRY-box 8 [Source:Xenbase;Acc:XB-GENE-480865])

HSP 1 Score: 181.8 bits (460), Expect = 1.463e-57
Identity = 78/148 (52.70%), Postives = 111/148 (75.00%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E++++ +KPDG QR L+G II RFE++GF L+A+K+M+  ++LL+ HY  L+DKPF+ +L++YM SGPVV M+WQG + VK  R ++G T P  SLPGTIRGDFC   GRN++HGSDS + A+REI+LWF P E+  ++   E W+ E
Sbjct:   41 ERTFLAIKPDGYQRRLIGEIIRRFEKKGFHLVAMKIMQASEQLLKQHYIALQDKPFYDRLVKYMGSGPVVAMVWQGLDVVKTARLMIGETNPAHSLPGTIRGDFCVDVGRNVIHGSDSRESAQREIALWFQPDELVCWQDSTESWIYE 188

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Match: man1c1 (mannosidase, alpha, class 1C, member 1 [Source:Xenbase;Acc:XB-GENE-6076350])

HSP 1 Score: 163.31 bits (412), Expect = 2.111e-50
Identity = 73/143 (51.05%), Postives = 100/143 (69.93%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNE 487
            E++ I VKPDGVQR LVG II RFEQRGF L+ LK+++  + +L  HY DL+ KPF+  L+ YM SGPVV M+W+G   V+  RA++G T    + PGTIRGDF     RN++H SDSV+ A+REISLWF+  E+  ++  ++
Sbjct:   38 ERTLIAVKPDGVQRKLVGEIIKRFEQRGFTLVGLKLLQASEGILAEHYHDLRRKPFYPALLRYMASGPVVAMVWEGHNVVRTSRAMVGDTDSSQAKPGTIRGDFSVHISRNVIHASDSVEVAEREISLWFHSGELISWETSDQ 180

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
Match: Nme1 (NME/NM23 nucleoside diphosphate kinase 1 [Source:MGI Symbol;Acc:MGI:97355])

HSP 1 Score: 204.527 bits (519), Expect = 3.583e-67
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK ++  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV  A++EISLWF P+E+ +YK C + W+ E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
Match: Nme2 (NME/NM23 nucleoside diphosphate kinase 2 [Source:MGI Symbol;Acc:MGI:97356])

HSP 1 Score: 201.06 bits (510), Expect = 7.717e-66
Identity = 89/148 (60.14%), Postives = 114/148 (77.03%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+A+K ++  ++ L+ HY DLKD+PFF  L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF P+E+ DYK C   WV E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE 152

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Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+A+K ++  ++ L+ HY DLKD+PFF  L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF P+E+ DYK C   WV E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
Match: Gm20390 (predicted gene 20390 [Source:MGI Symbol;Acc:MGI:5141855])

HSP 1 Score: 201.06 bits (510), Expect = 2.802e-64
Identity = 89/148 (60.14%), Postives = 114/148 (77.03%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+A+K ++  ++ L+ HY DLKD+PFF  L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF P+E+ DYK C   WV E
Sbjct:  120 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIHLWFKPEELIDYKSCAHDWVYE 267

HSP 2 Score: 153.68 bits (387), Expect = 9.269e-46
Identity = 67/115 (58.26%), Postives = 87/115 (75.65%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVH 400
             E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK ++  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GR + +
Sbjct:    4 SERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRTMAN 118

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
Match: Nme3 (NME/NM23 nucleoside diphosphate kinase 3 [Source:MGI Symbol;Acc:MGI:1930182])

HSP 1 Score: 184.882 bits (468), Expect = 3.855e-59
Identity = 80/149 (53.69%), Postives = 114/149 (76.51%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
             E++++ VKPDGVQR LVG I+ RFE++GFKL+ALK+++  ++LL  HY +L++KPF+S+L++YM SGPVV M+WQG + V   RAL+GAT P D++PGTIRGDFC   G+N++HGSDSV+ A REI+LWF   E+  ++     W+ E
Sbjct:   21 NERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYVELREKPFYSRLVKYMSSGPVVAMVWQGLDVVHASRALIGATDPGDAMPGTIRGDFCMEVGKNVIHGSDSVESAHREIALWFREAELLCWEDSAGHWLYE 169

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Match: sp|Q05982|NDKA_RAT (Nucleoside diphosphate kinase A OS=Rattus norvegicus OX=10116 GN=Nme1 PE=1 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 5.734e-67
Identity = 91/148 (61.49%), Postives = 116/148 (78.38%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK ++  + LL+ HY DLKD+PFFS L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EISLWF P+E+ DYK C + W+ E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFIQASEDLLKEHYIDLKDRPFFSGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEISLWFQPEELVDYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Match: sp|P52174|NDKA1_BOVIN (Nucleoside diphosphate kinase A 1 OS=Bos taurus OX=9913 GN=NME1-1 PE=1 SV=3)

HSP 1 Score: 205.682 bits (522), Expect = 9.273e-67
Identity = 88/149 (59.06%), Postives = 118/149 (79.19%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
             E+++I +KPDGVQRGL+G II RFEQ+GF+L+A+K M+  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI+LWF+P+E+ +YK C + W+ E
Sbjct:    4 SERTFIAIKPDGVQRGLIGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIALWFHPEELVNYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Match: sp|P15532|NDKA_MOUSE (Nucleoside diphosphate kinase A OS=Mus musculus OX=10090 GN=Nme1 PE=1 SV=1)

HSP 1 Score: 204.527 bits (519), Expect = 2.506e-66
Identity = 89/148 (60.14%), Postives = 115/148 (77.70%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQRGLVG II RFEQ+GF+L+ LK ++  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV  A++EISLWF P+E+ +YK C + W+ E
Sbjct:    5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFLQASEDLLKEHYTDLKDRPFFTGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFQPEELVEYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Match: sp|P52175|NDKA2_BOVIN (Nucleoside diphosphate kinase A 2 OS=Bos taurus OX=9913 GN=NME1-2 PE=1 SV=3)

HSP 1 Score: 204.142 bits (518), Expect = 3.403e-66
Identity = 88/149 (59.06%), Postives = 117/149 (78.52%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
             E+++I +KPDGVQRGL+G II RFEQ+GF+L+A+K M+  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI+LWF P+E+ +YK C + W+ E
Sbjct:    4 SERTFIAIKPDGVQRGLMGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIALWFRPEELVNYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Match: sp|Q50KA9|NDKA_CANLF (Nucleoside diphosphate kinase A OS=Canis lupus familiaris OX=9615 GN=NME1 PE=2 SV=1)

HSP 1 Score: 203.756 bits (517), Expect = 5.211e-66
Identity = 89/148 (60.14%), Postives = 116/148 (78.38%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E+++I +KPDGVQR LVG II RFEQ+GF+LIA+K+++  + LL+ HY DLKD+PFF+ L++YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDSV+ A++EI LWF P+E+ DYK C + W+ E
Sbjct:    5 ERTFIAIKPDGVQRSLVGEIIKRFEQKGFRLIAMKLIQASEDLLKEHYIDLKDRPFFAGLVKYMQSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFQPEELVDYKSCAQNWIYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Match: A0A0F7CYH3 (Nucleoside diphosphate kinase (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 347.051 bits (889), Expect = 8.283e-120
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 2

Query:    2 MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE
Sbjct:    9 MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 175

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Match: A0A267FR79 (Nucleoside diphosphate kinase (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008873g2 PE=3 SV=1)

HSP 1 Score: 232.646 bits (592), Expect = 6.497e-75
Identity = 105/148 (70.95%), Postives = 126/148 (85.14%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E++YIM+KPDGVQRGLVG II RFEQRGF+L+A+KMM+P + LLE HY DLK KPFF  LI+YMLSGPVVCM+W+G E VKIGR +LGAT+PIDSLPGTIRGD+C V GRNIVHGSD+V  A++EI+LWF P+E+ DYKL N  W+ E
Sbjct:    9 ERTYIMIKPDGVQRGLVGKIIKRFEQRGFRLVAMKMMQPGRPLLEEHYGDLKAKPFFPGLIDYMLSGPVVCMVWEGEEVVKIGRMMLGATKPIDSLPGTIRGDYCIVTGRNIVHGSDAVASAQKEIALWFKPEELVDYKLANHGWIYE 156

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Match: A0A267FLE0 (Nucleoside diphosphate kinase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008873g3 PE=3 SV=1)

HSP 1 Score: 232.261 bits (591), Expect = 9.429e-75
Identity = 105/148 (70.95%), Postives = 126/148 (85.14%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E++YIM+KPDGVQRGLVG II RFEQRGF+L+A+KMM+P + LLE HY DLK KPFF  LI+YMLSGPVVCM+W+G E VKIGR +LGAT+PIDSLPGTIRGD+C V GRNIVHGSD+V  A++EI+LWF P+E+ DYKL N  W+ E
Sbjct:   10 ERTYIMIKPDGVQRGLVGKIIKRFEQRGFRLVAMKMMQPGRPLLEEHYGDLKAKPFFPGLIDYMLSGPVVCMVWEGEEVVKIGRMMLGATKPIDSLPGTIRGDYCIVTGRNIVHGSDAVASAQKEIALWFKPEELVDYKLANHGWIYE 157

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Match: A0A086PJ18 (Nucleoside diphosphate kinase OS=Toxoplasma gondii VAND OX=933077 GN=TGVAND_295350 PE=3 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 2.336e-67
Identity = 98/149 (65.77%), Postives = 115/149 (77.18%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            QE++YIMVKPDGVQRGLV  +I RFEQRG+KL+ALKM  PD  LLE HY DLK KPFF  LI YM SGPVVCM+W+G + VK GR +LG TRP++S PGT+RGDFC   GRNIVHGSDSV+ A +EISLWF P+EI ++      WV E
Sbjct:    6 QERTYIMVKPDGVQRGLVSEVIRRFEQRGYKLVALKMKSPDATLLEEHYADLKGKPFFPGLISYMTSGPVVCMVWEGTDVVKQGRRMLGETRPLESNPGTLRGDFCIDVGRNIVHGSDSVESANKEISLWFTPEEICEWTSAQHKWVYE 154

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Match: A0A139XJX6 (Nucleoside diphosphate kinase OS=Toxoplasma gondii ARI OX=1074872 GN=TGARI_295350 PE=3 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 2.336e-67
Identity = 98/149 (65.77%), Postives = 115/149 (77.18%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            QE++YIMVKPDGVQRGLV  +I RFEQRG+KL+ALKM  PD  LLE HY DLK KPFF  LI YM SGPVVCM+W+G + VK GR +LG TRP++S PGT+RGDFC   GRNIVHGSDSV+ A +EISLWF P+EI ++      WV E
Sbjct:    6 QERTYIMVKPDGVQRGLVSEVIRRFEQRGYKLVALKMKSPDATLLEEHYADLKGKPFFPGLISYMTSGPVVCMVWEGTDVVKQGRRMLGETRPLESNPGTLRGDFCIDVGRNIVHGSDSVESANKEISLWFTPEEICEWTSAQHKWVYE 154

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Match: ENSAMXT00000008173.2 (nucleoside diphosphate kinase A-like [Source:NCBI gene;Acc:103046328])

HSP 1 Score: 199.134 bits (505), Expect = 6.805e-65
Identity = 86/151 (56.95%), Postives = 112/151 (74.17%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
            M   QE+++I +KPDGVQRGL+G II RFE +GFKL+ LK++   + LL+ HY DLKD+PFF  L+ YM SGPVV M+W+G   +K GR +LG T P DS PGTIRGD+C   GRNI+HGSDS+D A  EISLWF P+E+ +Y  C++ W+
Sbjct:   23 MASNQERTFIAIKPDGVQRGLIGEIIKRFELKGFKLVGLKILHASEDLLKQHYSDLKDRPFFPGLVSYMSSGPVVAMVWEGCNVIKTGRVMLGETNPADSKPGTIRGDYCIQVGRNIIHGSDSLDSASTEISLWFTPEELCNYSKCHDTWI 173

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Match: NME2 (nucleoside diphosphate kinase A2 [Source:NCBI gene;Acc:103034272])

HSP 1 Score: 196.823 bits (499), Expect = 2.800e-64
Identity = 85/153 (55.56%), Postives = 113/153 (73.86%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M    E+++I +KPDGVQRGL+G I+ RFEQ+GF+L+A+K ++  + LL+ HY DLKD+PF+  L++YM SGPV+ M+W+G   VK GR +LG T P DS PGTIRGD C   GRNI+HGSDSVD A +EISLWF P+E+  +K C   W+ E
Sbjct:    1 MAAKTERTFIAIKPDGVQRGLMGEIVKRFEQKGFRLVAMKFLQASEDLLKQHYIDLKDRPFYPGLVKYMSSGPVLAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDLCIEVGRNIIHGSDSVDSANKEISLWFKPEELVSFKSCAHEWIYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Match: ENSAMXT00000034489.1 (nucleoside diphosphate kinase A2-like [Source:NCBI gene;Acc:103034806])

HSP 1 Score: 188.348 bits (477), Expect = 7.579e-61
Identity = 80/148 (54.05%), Postives = 112/148 (75.68%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            E++++ +KPDGVQRGL+G I+ RFEQ+GF+L+A+K ++  + LL+ HY DLKD PF++ L++YM SGPV+ M+W+G   VK GR +LG T P DS PGTIRGD C   GRN++HGSDSVD A +EI+LWF P+E+  +K C   ++ E
Sbjct:    6 ERTFVAIKPDGVQRGLMGEIVKRFEQKGFRLVAMKFLQASEDLLKQHYIDLKDLPFYAGLVKYMSSGPVLAMVWEGANVVKTGRVMLGETNPADSKPGTIRGDLCIDIGRNLIHGSDSVDSANKEINLWFKPEEMVSFKCCAHEYIYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Match: nme3 (NME/NM23 nucleoside diphosphate kinase 3 [Source:NCBI gene;Acc:111193103])

HSP 1 Score: 180.644 bits (457), Expect = 2.077e-57
Identity = 77/147 (52.38%), Postives = 110/147 (74.83%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
             E++++ VKPDGVQR LVG II RFE++GFKL+ +K+++  ++ L  HY DL+++PF+  L++YM SGP+V M+WQG + V++ R +LG T P DSLPGTIRGDFC   GRN++HGSDSV+ A+REISLWF   E+  +    + W+
Sbjct:   32 NERTFLAVKPDGVQRKLVGEIIRRFERKGFKLVGMKLLQASEEQLMEHYWDLRERPFYKGLVKYMSSGPIVAMVWQGLDVVRMSRRMLGETNPADSLPGTIRGDFCVEVGRNVIHGSDSVESAQREISLWFKDYELFCWDESTDHWI 178

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Match: nme3 (NME/NM23 nucleoside diphosphate kinase 3 [Source:NCBI gene;Acc:111193103])

HSP 1 Score: 179.489 bits (454), Expect = 3.546e-57
Identity = 77/147 (52.38%), Postives = 110/147 (74.83%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
             E++++ VKPDGVQR LVG II RFE++GFKL+ +K+++  ++ L  HY DL+++PF+  L++YM SGP+V M+WQG + V++ R +LG T P DSLPGTIRGDFC   GRN++HGSDSV+ A+REISLWF   E+  +    + W+
Sbjct:   21 NERTFLAVKPDGVQRKLVGEIIRRFERKGFKLVGMKLLQASEEQLMEHYWDLRERPFYKGLVKYMSSGPIVAMVWQGLDVVRMSRRMLGETNPADSLPGTIRGDFCVEVGRNVIHGSDSVESAQREISLWFKDYELFCWDESTDHWI 167

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Sea Lamprey
Match: nme3 (NME/NM23 nucleoside diphosphate kinase 3 [Source:ZFIN;Acc:ZDB-GENE-000210-34])

HSP 1 Score: 175.252 bits (443), Expect = 3.122e-56
Identity = 79/149 (53.02%), Postives = 107/149 (71.81%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
             E++ + +KPDGVQR L+G I+ RFE +G KL+A+K +KP   LL+ HY DLKDK F+S L+++M SGPV+ M+W+G   V+  R +LG T P DS PGTIRGDFC   GRN++HGSDS + A++EISLWF P+E+  +    E WV E
Sbjct:   20 HERTLLAIKPDGVQRRLMGDIVKRFEGKGLKLVAMKFLKPPVALLQQHYIDLKDKAFYSSLVQFMNSGPVLAMVWEGNGVVRTCRRMLGETDPADSAPGTIRGDFCIDIGRNVIHGSDSEESAQKEISLWFQPEELVTWYSNTEAWVYE 168

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Sea Lamprey
Match: nme6 (NME/NM23 nucleoside diphosphate kinase 6 [Source:NCBI gene;Acc:58120])

HSP 1 Score: 68.1662 bits (165), Expect = 1.148e-14
Identity = 42/141 (29.79%), Postives = 71/141 (50.35%), Query Frame = 2

Query:   74 MVKPDGVQRGLVGTIIMR-FEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGAT---RPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCN 484
            ++KPD +  G+    + +   +  F ++  K ++  +   E  Y   K K FF +L+E+M SGP+   +    +AV+  R L+G T   R + + P +IR  +     RN  HGSDS   A +EIS +F   ++  +  CN
Sbjct:   16 LLKPDALAHGIAWEAVHQDVLKNKFLIVKSKELRLKRSDSERFYAAHKGKFFFQRLVEFMASGPIRVYVLAHHDAVRGWRELMGPTKVFRAVHTAPESIRACYGLTDTRNTTHGSDSSASALQEISFFFPEFDVACW--CN 154

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008106.1 (pep scaffold:Pmarinus_7.0:GL476850:19893:22834:-1 gene:ENSPMAG00000007330.1 transcript:ENSPMAT00000008106.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.595 bits (109), Expect = 2.949e-7
Identity = 26/118 (22.03%), Postives = 58/118 (49.15%), Query Frame = 2

Query:  104 LVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRP---IDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            +  T++   ++ GF +   K +   ++     Y++ + + +F  L+++M  GP + ++    +AV+  R L+G   P     + P ++R  F +    N +HG+ ++  A+  I L F
Sbjct:    3 MADTVLGAIKEAGFHIAMQKEVILTEEQAREFYREHEGQDYFGTLVKHMTRGPSLMLVLNREDAVEEWRRLMGPADPDVARKTAPESLRARFARSLLENALHGASNLHHAQENIHLLF 120

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Yeast
Match: YNK1 (Nucleoside diphosphate kinase; catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000001550])

HSP 1 Score: 178.718 bits (452), Expect = 5.034e-58
Identity = 80/153 (52.29%), Postives = 111/153 (72.55%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M    E+++I VKPDGVQRGLV  I+ RFE++G+KL+A+K++K D KLLE HY +   KPFF K++ +M SGP++  +W+G + V+ GR +LGAT P+ S PGTIRGDF    GRN+ HGSDSVD A+REI+LWF  +E+ D++     W+ E
Sbjct:    1 MSSQTERTFIAVKPDGVQRGLVSQILSRFEKKGYKLVAIKLVKADDKLLEQHYAEHVGKPFFPKMVSFMKSGPILATVWEGKDVVRQGRTILGATNPLGSAPGTIRGDFGIDLGRNVCHGSDSVDSAEREINLWFKKEELVDWESNQAKWIYE 153

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Match: EDO37954 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE67])

HSP 1 Score: 189.889 bits (481), Expect = 8.012e-62
Identity = 86/145 (59.31%), Postives = 111/145 (76.55%), Query Frame = 2

Query:   38 SIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDY 472
            S++    E+++IMVKPDGVQRGLVG II RFEQ+GFKL+ALKM++  ++ L+ HY DL   PF+  L+++M SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC   GRNI+HGSDS D A +EI+LWF+PKE+ D+
Sbjct:   10 SLLQNKGERTFIMVKPDGVQRGLVGEIIKRFEQKGFKLVALKMVQESEEHLKKHYADLAHLPFYPGLVKFMSSGPVVAMVWEGAGVVKTGRVMLGETNPADSKPGTIRGDFCVHIGRNIIHGSDSTDSANKEIALWFSPKELVDW 154

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Match: EDO37955 (Nucleoside diphosphate kinase [Source:UniProtKB/TrEMBL;Acc:A7SE68])

HSP 1 Score: 163.31 bits (412), Expect = 1.904e-51
Identity = 73/149 (48.99%), Postives = 98/149 (65.77%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
             E++++M+KPD V RGL+G II RFE++GFKL+A+K +K  +     HY+ L    F+  L +YM   PV  M+W+G   VK  R +LG T P  SLPGTIRGDF    GRNI+HGSD+V+ AK EI+LWF   E+ D+  CN  W+ E
Sbjct:    4 NERTFLMIKPDAVSRGLIGEIISRFEKKGFKLVAMKFVKKSEDHFRKHYESLAKLKFYDGLCKYMSQTPVCAMVWEGLGVVKTARVMLGETDPAKSLPGTIRGDFSIHIGRNIIHGSDAVETAKEEIALWFKDDELVDWTPCNNPWMYE 152

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Match: EDO50065 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFA5])

HSP 1 Score: 94.7449 bits (234), Expect = 1.740e-23
Identity = 53/153 (34.64%), Postives = 85/153 (55.56%), Query Frame = 2

Query:    8 QQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPI---DSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPK 457
            +   N L++I+      EK+  M+KPD V  G +G I+   +Q GFKL   KM++ ++K     YQ+   +PF+ +L+E++ SGPVV    +G  AV   R +LG T      +  P ++R  F     +N  HGSDS + A+RE+S +F+ +
Sbjct:   78 KHTTNRLKNIN------EKTLAMIKPDAV--GCLGGIMEMIDQAGFKLCRAKMVRLNRKEASDFYQEHASQPFYDRLVEFISSGPVVAFELKGPGAVDSWRKVLGPTDSATARNQAPLSVRAKFGTDNTKNAAHGSDSTESAEREVSFFFDKR 222

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Match: EDO34502 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SP47])

HSP 1 Score: 94.3597 bits (233), Expect = 7.457e-23
Identity = 53/153 (34.64%), Postives = 85/153 (55.56%), Query Frame = 2

Query:    8 QQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPI---DSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPK 457
            +   N L++I+      EK+  M+KPD V  G +G I+   +Q GFKL   KM++ ++K     YQ+   +PF+ +L+E++ SGPVV    +G  AV   R +LG T      +  P ++R  F     +N  HGSDS + A+RE+S +F+ +
Sbjct:   78 KHTTNRLKNIN------EKTLAMIKPDAV--GCLGGIMEMIDQAGFKLCRAKMVRLNRKEASDFYQEHASQPFYDRLVEFISSGPVVAFELKGPGAVDSWRKVLGPTDSATARNQAPLSVRAKFGTDNTKNAAHGSDSTESAEREVSFFFDKR 222

HSP 2 Score: 50.8322 bits (120), Expect = 1.050e-7
Identity = 33/133 (24.81%), Postives = 63/133 (47.37%), Query Frame = 2

Query:   65 SYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKD--KPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDS---LPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            +  +VKP  V  GL G I++  +  GF++ AL+M   ++   E  ++  K     +   ++E + SGP + +  +G +  K  R  +G   P  +    P ++R  F +   +N VH +D  +    E+  +F
Sbjct:  233 TLCVVKPHAVADGLSGRIVLAIQDAGFEISALQMFHLERANAEEFHEVYKGVVNEYERNMVEELCSGPCLAVEVRGQDVTKTFRDFVGPADPEIARHLRPKSLRAKFGKDKIKNAVHCTDLPEDGLLEVEYFF 365

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Match: EDO39201 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAT1])

HSP 1 Score: 63.5438 bits (153), Expect = 2.033e-12
Identity = 38/137 (27.74%), Postives = 67/137 (48.91%), Query Frame = 2

Query:   50 VYQEKSYIMVKPDGVQRG-LVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGAT---RPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            ++ E++  ++KPD V +   +  II+   Q GF ++  +      +     Y +   K FF  L+ YM SGP++ ++     A+   R L+G T   +  D  P ++R  +   + RN +HGSD    A +EI  +F
Sbjct:   15 IHIERTLALIKPDAVHKSDEIEEIIL---QHGFTILQKRRAHLTPEQTSDFYAEHYGKMFFPSLVAYMSSGPIMALVLARENAISYWRQLIGPTNTQKARDQAPESLRAIYGTDSTRNALHGSDGTVSADKEIHFFF 148

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Match: nme3 (NME/NM23 nucleoside diphosphate kinase 3 [Source:NCBI gene;Acc:101158025])

HSP 1 Score: 194.512 bits (493), Expect = 4.729e-63
Identity = 84/147 (57.14%), Postives = 112/147 (76.19%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
             E+++I VKPDGVQR LVG I+ RFE++GFKL+ LK+++  + +L  HY DL+ KPF+++LI YM SGPVV M+WQG E VK  R +LG T P +SLPGTIRGDFC   G+N++HGSDSV+ A+REISLWF PKE+  +K  +  W+
Sbjct:   21 NERTFIAVKPDGVQRKLVGEIVRRFEKKGFKLVGLKLVRASEDILREHYWDLRTKPFYNRLISYMSSGPVVAMVWQGLEVVKTARKMLGETNPAESLPGTIRGDFCVEVGKNVIHGSDSVESAQREISLWFGPKELHRWKSSSSQWI 167

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Match: nme2a (nucleoside diphosphate kinase A [Source:NCBI gene;Acc:101158485])

HSP 1 Score: 189.504 bits (480), Expect = 3.688e-61
Identity = 84/147 (57.14%), Postives = 107/147 (72.79%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
            QE+++I +KPDGVQRG++G II RFE +GFKL+ +KM++  + LL  HY DLKD+PFF  L+ YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC    +NI+HGSDSV+ A  EISLWF P+E+  Y  C   W+
Sbjct:   15 QERTFIAIKPDGVQRGIIGEIIKRFEMKGFKLVGMKMVQASEDLLMKHYIDLKDRPFFPTLVNYMSSGPVVAMVWEGKGVVKTGRVMLGETNPADSKPGTIRGDFCIDVSKNIIHGSDSVESANTEISLWFQPEELVSYTSCAFSWL 161

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Match: nme2a (nucleoside diphosphate kinase A [Source:NCBI gene;Acc:101158485])

HSP 1 Score: 188.734 bits (478), Expect = 4.870e-61
Identity = 84/147 (57.14%), Postives = 107/147 (72.79%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
            QE+++I +KPDGVQRG++G II RFE +GFKL+ +KM++  + LL  HY DLKD+PFF  L+ YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC    +NI+HGSDSV+ A  EISLWF P+E+  Y  C   W+
Sbjct:    5 QERTFIAIKPDGVQRGIIGEIIKRFEMKGFKLVGMKMVQASEDLLMKHYIDLKDRPFFPTLVNYMSSGPVVAMVWEGKGVVKTGRVMLGETNPADSKPGTIRGDFCIDVSKNIIHGSDSVESANTEISLWFQPEELVSYTSCAFSWL 151

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Match: nme2a (nucleoside diphosphate kinase A [Source:NCBI gene;Acc:101158485])

HSP 1 Score: 189.119 bits (479), Expect = 5.569e-61
Identity = 84/147 (57.14%), Postives = 107/147 (72.79%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
            QE+++I +KPDGVQRG++G II RFE +GFKL+ +KM++  + LL  HY DLKD+PFF  L+ YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC    +NI+HGSDSV+ A  EISLWF P+E+  Y  C   W+
Sbjct:   19 QERTFIAIKPDGVQRGIIGEIIKRFEMKGFKLVGMKMVQASEDLLMKHYIDLKDRPFFPTLVNYMSSGPVVAMVWEGKGVVKTGRVMLGETNPADSKPGTIRGDFCIDVSKNIIHGSDSVESANTEISLWFQPEELVSYTSCAFSWL 165

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Match: nme2a (nucleoside diphosphate kinase A [Source:NCBI gene;Acc:101158485])

HSP 1 Score: 188.348 bits (477), Expect = 7.774e-61
Identity = 84/147 (57.14%), Postives = 107/147 (72.79%), Query Frame = 2

Query:   56 QEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWV 496
            QE+++I +KPDGVQRG++G II RFE +GFKL+ +KM++  + LL  HY DLKD+PFF  L+ YM SGPVV M+W+G   VK GR +LG T P DS PGTIRGDFC    +NI+HGSDSV+ A  EISLWF P+E+  Y  C   W+
Sbjct:    8 QERTFIAIKPDGVQRGIIGEIIKRFEMKGFKLVGMKMVQASEDLLMKHYIDLKDRPFFPTLVNYMSSGPVVAMVWEGKGVVKTGRVMLGETNPADSKPGTIRGDFCIDVSKNIIHGSDSVESANTEISLWFQPEELVSYTSCAFSWL 154

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BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Match: SMESG000008082.1 (SMESG000008082.1)

HSP 1 Score: 347.051 bits (889), Expect = 1.739e-123
Identity = 167/167 (100.00%), Postives = 167/167 (100.00%), Query Frame = 2

Query:    2 MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE
Sbjct:    1 MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 167

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Match: SMESG000008082.1 (SMESG000008082.1)

HSP 1 Score: 318.546 bits (815), Expect = 1.697e-112
Identity = 153/153 (100.00%), Postives = 153/153 (100.00%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE
Sbjct:    1 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 153

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Match: SMESG000056344.1 (SMESG000056344.1)

HSP 1 Score: 257.684 bits (657), Expect = 2.261e-88
Identity = 116/153 (75.82%), Postives = 132/153 (86.27%), Query Frame = 2

Query:   44 MDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFNPKEIGDYKLCNEVWVQE 502
            M  Y E+SYIM+KPDG QRGLVG II RFE+RGFKL A+KMM PD+ +LE HY+DLK+K FF  LI YMLSGPVVCM+WQG+EAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRN++HGSD V+ A +EI+LWFNP EI +YKLC E WVQE
Sbjct:    1 MANYNEQSYIMIKPDGAQRGLVGKIISRFEERGFKLAAMKMMTPDRAMLEKHYEDLKEKSFFPGLINYMLSGPVVCMVWQGYEAVKIGRALLGATRPIDSLPGTIRGDFCQVAGRNVIHGSDGVESAMKEIALWFNPDEIAEYKLCTEEWVQE 153

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Match: SMESG000039529.1 (SMESG000039529.1)

HSP 1 Score: 68.5514 bits (166), Expect = 5.756e-14
Identity = 41/136 (30.15%), Postives = 66/136 (48.53%), Query Frame = 2

Query:   50 VYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGATRPID---SLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            ++ E++  ++KPD + R     I+ R    GF +I  K +    +     Y +   K FF  LI YM SGPV  ++     A+ + R ++G T  +    + P ++R  +     RN  HGSDS   A+REI  +F
Sbjct:   14 IFVERTLAIIKPDAIHR--TDEIVKRILDHGFHIIQQKRVHLTPEEASDFYTEHFGKLFFPSLIAYMSSGPVHVIVLSHENAISLWRDIIGPTNAMKAKITSPESLRAIYGTDDQRNGFHGSDSFSSAEREIRFFF 147

[Close]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Match: SMESG000061846.1 (SMESG000061846.1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.774e-13
Identity = 46/135 (34.07%), Postives = 65/135 (48.15%), Query Frame = 2

Query:   59 EKSYIMVKPDGVQR--GLVGTIIMRFEQRGFKLIALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVKIGRALLGAT---RPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWF 448
            E +  + KPD VQR    V        +   +++  K +  +K L E  Y + K K ++ +L+ YM  G +   I +G  A+   R LLG T   R I   PG++RG F     RN  HGSDS + A  EI L F
Sbjct:    5 ELTLALFKPD-VQRFRNYVKQTENIISKYNLEILHHKQLVINKNLAEKFYTNHKGKFYYDRLVNYMTCGLIGAYILRGENAISNWRLLLGPTKVYRAIHEQPGSLRGQFGLTDTRNGYHGSDSQENAFTEIKLIF 138

The following BLAST results are available for this feature:

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Celegans
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Zebrafish
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Sea Lamprey
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Yeast
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NME1	1.395e-66	60.14	NME/NM23 nucleoside diphosphate kinase 1 [Source:H...	[more]
NME1	3.364e-66	60.14	NME/NM23 nucleoside diphosphate kinase 1 [Source:H...	[more]
NME1	3.364e-66	60.14	NME/NM23 nucleoside diphosphate kinase 1 [Source:H...	[more]
NME2	4.847e-66	60.81	NME/NM23 nucleoside diphosphate kinase 2 [Source:H...	[more]
NME2	4.847e-66	60.81	NME/NM23 nucleoside diphosphate kinase 2 [Source:H...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ndk-1	6.204e-67	66.67	Nucleoside diphosphate kinase [Source:UniProtKB/T...	[more]
ndk-1	6.204e-67	66.67	Nucleoside diphosphate kinase [Source:UniProtKB/T...	[more]
ndk-1	6.204e-67	66.67	Nucleoside diphosphate kinase [Source:UniProtKB/T...	[more]
ndk-1	6.204e-67	66.67	Nucleoside diphosphate kinase [Source:UniProtKB/T...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
awd	3.997e-66	59.35	gene:FBgn0000150 transcript:FBtr0346150	[more]
awd	3.997e-66	59.35	gene:FBgn0000150 transcript:FBtr0339146	[more]
awd	1.003e-65	60.13	gene:FBgn0000150 transcript:FBtr0346611	[more]
nmdyn-D6	6.045e-13	32.33	gene:FBgn0030573 transcript:FBtr0073933	[more]
nmdyn-D7	9.139e-7	25.53	gene:FBgn0028997 transcript:FBtr0082083	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nme2a	2.063e-69	60.53	NME/NM23 nucleoside diphosphate kinase 2a [Source:...	[more]
nme2a	2.063e-69	60.53	NME/NM23 nucleoside diphosphate kinase 2a [Source:...	[more]
nme2a	2.063e-69	60.53	NME/NM23 nucleoside diphosphate kinase 2a [Source:...	[more]
nme2a	2.063e-69	60.53	NME/NM23 nucleoside diphosphate kinase 2a [Source:...	[more]
nme2b.1	1.676e-65	57.52	NME/NM23 nucleoside diphosphate kinase 2b, tandem ...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
c1orf112	2.787e-66	56.88	chromosome 1 open reading frame 112 [Source:Xenbas...	[more]
c1orf112	2.098e-64	57.52	chromosome 1 open reading frame 112 [Source:Xenbas...	[more]
sox8	6.045e-58	52.70	SRY-box 8 [Source:Xenbase;Acc:XB-GENE-480865]	[more]
sox8	1.463e-57	52.70	SRY-box 8 [Source:Xenbase;Acc:XB-GENE-480865]	[more]
man1c1	2.111e-50	51.05	mannosidase, alpha, class 1C, member 1 [Source:Xen...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Nme1	3.583e-67	60.14	NME/NM23 nucleoside diphosphate kinase 1 [Source:M...	[more]
Nme2	7.717e-66	60.14	NME/NM23 nucleoside diphosphate kinase 2 [Source:M...	[more]
Nme2	7.717e-66	60.14	NME/NM23 nucleoside diphosphate kinase 2 [Source:M...	[more]
Gm20390	2.802e-64	60.14	predicted gene 20390 [Source:MGI Symbol;Acc:MGI:51...	[more]
Nme3	3.855e-59	53.69	NME/NM23 nucleoside diphosphate kinase 3 [Source:M...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q05982\|NDKA_RAT	5.734e-67	61.49	Nucleoside diphosphate kinase A OS=Rattus norvegic...	[more]
sp\|P52174\|NDKA1_BOVIN	9.273e-67	59.06	Nucleoside diphosphate kinase A 1 OS=Bos taurus OX...	[more]
sp\|P15532\|NDKA_MOUSE	2.506e-66	60.14	Nucleoside diphosphate kinase A OS=Mus musculus OX...	[more]
sp\|P52175\|NDKA2_BOVIN	3.403e-66	59.06	Nucleoside diphosphate kinase A 2 OS=Bos taurus OX...	[more]
sp\|Q50KA9\|NDKA_CANLF	5.211e-66	60.14	Nucleoside diphosphate kinase A OS=Canis lupus fam...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0F7CYH3	8.283e-120	100.00	Nucleoside diphosphate kinase (Fragment) OS=Schmid...	[more]
A0A267FR79	6.497e-75	70.95	Nucleoside diphosphate kinase (Fragment) OS=Macros...	[more]
A0A267FLE0	9.429e-75	70.95	Nucleoside diphosphate kinase OS=Macrostomum ligna...	[more]
A0A086PJ18	2.336e-67	65.77	Nucleoside diphosphate kinase OS=Toxoplasma gondii...	[more]
A0A139XJX6	2.336e-67	65.77	Nucleoside diphosphate kinase OS=Toxoplasma gondii...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000008173.2	6.805e-65	56.95	nucleoside diphosphate kinase A-like [Source:NCBI ...	[more]
NME2	2.800e-64	55.56	nucleoside diphosphate kinase A2 [Source:NCBI gene...	[more]
ENSAMXT00000034489.1	7.579e-61	54.05	nucleoside diphosphate kinase A2-like [Source:NCBI...	[more]
nme3	2.077e-57	52.38	NME/NM23 nucleoside diphosphate kinase 3 [Source:N...	[more]
nme3	3.546e-57	52.38	NME/NM23 nucleoside diphosphate kinase 3 [Source:N...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
nme3	3.122e-56	53.02	NME/NM23 nucleoside diphosphate kinase 3 [Source:Z...	[more]
nme6	1.148e-14	29.79	NME/NM23 nucleoside diphosphate kinase 6 [Source:N...	[more]
ENSPMAT00000008106.1	2.949e-7	22.03	pep scaffold:Pmarinus_7.0:GL476850:19893:22834:-1 ...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
YNK1	5.034e-58	52.29	Nucleoside diphosphate kinase; catalyzes the trans...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37954	8.012e-62	59.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37955	1.904e-51	48.99	Nucleoside diphosphate kinase [Source:UniProtKB/T...	[more]
EDO50065	1.740e-23	34.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34502	7.457e-23	34.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39201	2.033e-12	27.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nme3	4.729e-63	57.14	NME/NM23 nucleoside diphosphate kinase 3 [Source:N...	[more]
nme2a	3.688e-61	57.14	nucleoside diphosphate kinase A [Source:NCBI gene;...	[more]
nme2a	4.870e-61	57.14	nucleoside diphosphate kinase A [Source:NCBI gene;...	[more]
nme2a	5.569e-61	57.14	nucleoside diphosphate kinase A [Source:NCBI gene;...	[more]
nme2a	7.774e-61	57.14	nucleoside diphosphate kinase A [Source:NCBI gene;...	[more]

BLAST of NME/NM23 nucleoside diphosphate kinase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000008082.1	1.739e-123	100.00	SMESG000008082.1	[more]
SMESG000008082.1	1.697e-112	100.00	SMESG000008082.1	[more]
SMESG000056344.1	2.261e-88	75.82	SMESG000056344.1	[more]
SMESG000039529.1	5.756e-14	30.15	SMESG000039529.1	[more]
SMESG000061846.1	2.774e-13	34.07	SMESG000061846.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30001801
GenBank	AKG62119.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001801 ID=SMED30001801|Name=NME/NM23 nucleoside diphosphate kinase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=663bp
TATGTATCAACAGAATTTAAATAGTTTACGTGATATTAGTATTATGGACG
TTTATCAAGAAAAGTCATACATTATGGTGAAGCCTGACGGTGTTCAACGT
GGTTTGGTCGGTACAATTATAATGCGATTTGAACAACGAGGATTTAAATT
AATAGCATTGAAAATGATGAAACCTGACAAAAAATTGTTAGAAACTCATT
ATCAAGATTTAAAGGATAAACCGTTTTTTTCCAAATTAATTGAATATATG
CTTTCTGGTCCTGTTGTTTGTATGATTTGGCAAGGATTTGAGGCAGTTAA
AATTGGACGGGCATTGTTAGGTGCTACAAGACCTATTGATTCATTGCCGG
GTACAATTCGAGGAGATTTTTGTCAAGTAGCTGGAAGAAATATTGTTCAT
GGATCGGATTCAGTAGATGGTGCTAAAAGGGAAATTTCTCTATGGTTTAA
TCCTAAGGAAATTGGAGATTATAAGTTATGTAATGAAGTATGGGTCCAAG
AGTGACTTATCAAGAAATTTTTGGAATGAACATCTTAAATCCTTTATCGG
TTTAGTGTAAACAGTATTTATTACGACAATTTATCCTTCGTGGTTATGAT
GTAATATATTATCATATATTATGATGTAATGTATTAGTGCTTCTACAATA
AATAGATTCTCTT

protein sequence of SMED30001801-orf-1

>SMED30001801-orf-1 ID=SMED30001801-orf-1|Name=SMED30001801-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=168bp
MYQQNLNSLRDISIMDVYQEKSYIMVKPDGVQRGLVGTIIMRFEQRGFKL
IALKMMKPDKKLLETHYQDLKDKPFFSKLIEYMLSGPVVCMIWQGFEAVK
IGRALLGATRPIDSLPGTIRGDFCQVAGRNIVHGSDSVDGAKREISLWFN
PKEIGDYKLCNEVWVQE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000101	muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR034907	NDK-like_dom
IPR036850	NDK-like_dom_sf
IPR001564	Nucleoside_diP_kinase
IPR023005	Nucleoside_diP_kinase_AS

Vocabulary: **biological process**
Term	Definition
GO:0006241	CTP biosynthetic process
GO:0006228	UTP biosynthetic process
GO:0006165	nucleoside diphosphate phosphorylation
GO:0006183	GTP biosynthetic process
GO:0016310	phosphorylation

Vocabulary: **molecular function**
Term	Definition
GO:0004550	nucleoside diphosphate kinase activity
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001564	Nucleoside diphosphate kinase	PRINTS	PR01243	NUCDPKINASE	coord: 66..85 score: 54.03 coord: 130..149 score: 65.73 coord: 86..103 score: 50.63 coord: 107..123 score: 68.12 coord: 22..44 score: 64.52
IPR034907	Nucleoside diphosphate kinase-like domain	SMART	SM00562	ndk_5	coord: 19..156 e-value: 3.7E-77 score: 272.3
IPR034907	Nucleoside diphosphate kinase-like domain	PFAM	PF00334	NDK	coord: 20..154 e-value: 2.4E-50 score: 170.0
IPR036850	Nucleoside diphosphate kinase-like domain superfamily	GENE3D	G3DSA:3.30.70.141		coord: 16..167 e-value: 1.8E-59 score: 201.9
IPR036850	Nucleoside diphosphate kinase-like domain superfamily	SUPERFAMILY	SSF54919	Nucleoside diphosphate kinase, NDK	coord: 18..165
None	No IPR available	PANTHER	PTHR11349:SF44	NUCLEOSIDE DIPHOSPHATE KINASE II, CHLOROPLASTIC	coord: 18..167
None	No IPR available	PANTHER	PTHR11349	NUCLEOSIDE DIPHOSPHATE KINASE	coord: 18..167
None	No IPR available	CDD	cd04413	NDPk_I	coord: 20..149 e-value: 4.53202E-84 score: 241.218
IPR023005	Nucleoside diphosphate kinase, active site	PROSITE	PS00469	NDP_KINASES	coord: 130..138