Nuclear receptor 2DBD gamma

Overview


Name	Nuclear receptor 2DBD gamma
Smed ID	SMED30001785
Length (bp)	2370

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Nuclear receptor 2DBD gamma (SMED30001785) t-SNE clustered cells

Violin plots show distribution of expression levels for Nuclear receptor 2DBD gamma (SMED30001785) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nuclear receptor 2DBD gamma (SMED30001785) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Nuclear receptor 2DBD gamma (SMED30001785) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001785

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30001785	h1SMcG0011863	SmedASXL_014455	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
oocyte	SMED30001785	h1SMcG0001619	Contig11	GPL15192	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30001785	h1SMcG0001619	Contig11	GPL15192	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30001785	h1SMcG0011863	Contig11	GPL15192	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30001785	h1SMcG0011863	Contig11	GPL15192	PMID:28434803 Rouhana et al., 2017
zeta neoblast	SMED30001785	h1SMcG0011863	dd_Smed_v4_16388_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Match: RORA (RAR related orphan receptor A [Source:HGNC Symbol;Acc:HGNC:10258])

HSP 1 Score: 94.3597 bits (233), Expect = 1.449e-19
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 1

Query:  355 MKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:    1 MMYFVIAAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 92

HSP 2 Score: 63.929 bits (154), Expect = 6.037e-10
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   18 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 98

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Match: PPARG (peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236])

HSP 1 Score: 92.8189 bits (229), Expect = 1.491e-19
Identity = 72/256 (28.12%), Postives = 115/256 (44.92%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSD-GNQRSISYS-----IPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNS-MMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K                         EISS I + N +  + R+++       I S P+    + +  +        F    + ++ + +  +    K  H+T       +  + ++     R  +    I  Y AK +PGF +L L+D+ T+++  ++ I+   LA    +D
Sbjct:    3 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKL--------------------LAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI----KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEY-AKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKD 231

HSP 2 Score: 69.3218 bits (168), Expect = 7.595e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:    5 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 75

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Match: PPARG (peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236])

HSP 1 Score: 92.0485 bits (227), Expect = 3.545e-19
Identity = 71/250 (28.40%), Postives = 115/250 (46.00%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNS-MMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K     EI          S +D    +++   ++  +       SY I S P+    + +  +        F    + ++ + +  +    K  H+T       +  + ++     R  +    I  Y AK +PGF +L L+D+ T+++  ++ I+   LA    +D
Sbjct:  107 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI---------SSDID----QLNPESADLRALAKHLYDSY-IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI----KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEY-AKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKD 335

HSP 2 Score: 70.0922 bits (170), Expect = 5.059e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  109 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 179

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Match: PPARG (peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236])

HSP 1 Score: 88.5817 bits (218), Expect = 7.034e-19
Identity = 44/91 (48.35%), Postives = 54/91 (59.34%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEI 678
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K     EI
Sbjct:  109 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197

HSP 2 Score: 70.0922 bits (170), Expect = 1.424e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  111 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 181

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Match: PPARG (peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236])

HSP 1 Score: 88.5817 bits (218), Expect = 7.295e-19
Identity = 44/91 (48.35%), Postives = 54/91 (59.34%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEI 678
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K     EI
Sbjct:  107 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 195

HSP 2 Score: 69.707 bits (169), Expect = 1.475e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  109 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 179

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Match: nhr-23 (Nuclear hormone receptor family member nhr-23 [Source:UniProtKB/Swiss-Prot;Acc:P41828])

HSP 1 Score: 97.0561 bits (240), Expect = 1.082e-20
Identity = 47/98 (47.96%), Postives = 64/98 (65.31%), Query Frame = 1

Query:  355 MKFFGLRSNKSKI---DISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M F GL  NKS +    I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:  106 MSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 202

HSP 2 Score: 69.3218 bits (168), Expect = 6.014e-12
Identity = 37/122 (30.33%), Postives = 65/122 (53.28%), Query Frame = 1

Query:   40 LDKNKVQSVILKTNTMLNNATFSS-PESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            +D N+V         + +N +F   PE+       ++E   C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:   91 IDTNRVD----MAGILPDNMSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 208

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Match: nhr-23 (Nuclear hormone receptor family member nhr-23 [Source:UniProtKB/Swiss-Prot;Acc:P41828])

HSP 1 Score: 97.0561 bits (240), Expect = 1.102e-20
Identity = 47/98 (47.96%), Postives = 64/98 (65.31%), Query Frame = 1

Query:  355 MKFFGLRSNKSKI---DISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M F GL  NKS +    I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:  106 MSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 202

HSP 2 Score: 69.3218 bits (168), Expect = 6.257e-12
Identity = 37/122 (30.33%), Postives = 65/122 (53.28%), Query Frame = 1

Query:   40 LDKNKVQSVILKTNTMLNNATFSS-PESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            +D N+V         + +N +F   PE+       ++E   C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:   91 IDTNRVD----MAGILPDNMSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 208

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Match: nhr-23 (Nuclear hormone receptor family member nhr-23 [Source:UniProtKB/Swiss-Prot;Acc:P41828])

HSP 1 Score: 97.0561 bits (240), Expect = 1.358e-20
Identity = 47/98 (47.96%), Postives = 64/98 (65.31%), Query Frame = 1

Query:  355 MKFFGLRSNKSKI---DISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M F GL  NKS +    I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:  141 MSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 237

HSP 2 Score: 69.3218 bits (168), Expect = 5.780e-12
Identity = 37/122 (30.33%), Postives = 65/122 (53.28%), Query Frame = 1

Query:   40 LDKNKVQSVILKTNTMLNNATFSS-PESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            +D N+V         + +N +F   PE+       ++E   C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:  126 IDTNRVD----MAGILPDNMSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 243

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Match: nhr-23 (Nuclear hormone receptor family member nhr-23 [Source:UniProtKB/Swiss-Prot;Acc:P41828])

HSP 1 Score: 90.5077 bits (223), Expect = 7.216e-19
Identity = 40/81 (49.38%), Postives = 56/81 (69.14%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:    7 IEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 86

HSP 2 Score: 67.3958 bits (163), Expect = 2.020e-11
Identity = 29/81 (35.80%), Postives = 49/81 (60.49%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:   12 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 92

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Match: nhr-23 (Nuclear hormone receptor family member nhr-23 [Source:UniProtKB/Swiss-Prot;Acc:P41828])

HSP 1 Score: 90.5077 bits (223), Expect = 7.637e-19
Identity = 40/81 (49.38%), Postives = 56/81 (69.14%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:    7 IEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 86

HSP 2 Score: 67.0106 bits (162), Expect = 2.060e-11
Identity = 29/81 (35.80%), Postives = 49/81 (60.49%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:   12 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 92

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Match: Hr3 (gene:FBgn0000448 transcript:FBtr0112799)

HSP 1 Score: 98.5969 bits (244), Expect = 2.251e-21
Identity = 75/293 (25.60%), Postives = 130/293 (44.37%), Query Frame = 1

Query:  382 KSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRISESNSD-GNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            +++I+I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +    SN++ G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:   14 RAQIEI--IPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 303

HSP 2 Score: 67.3958 bits (163), Expect = 2.666e-11
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:   22 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 102

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Match: Hr3 (gene:FBgn0000448 transcript:FBtr0088368)

HSP 1 Score: 98.5969 bits (244), Expect = 2.658e-21
Identity = 76/295 (25.76%), Postives = 129/295 (43.73%), Query Frame = 1

Query:  382 KSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRIS---ESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            K++I+I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +  S    +N  G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:   43 KAQIEI--IPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 334

HSP 2 Score: 67.0106 bits (162), Expect = 3.121e-11
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:   51 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 131

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Match: Hr3 (gene:FBgn0000448 transcript:FBtr0306345)

HSP 1 Score: 98.5969 bits (244), Expect = 2.658e-21
Identity = 76/295 (25.76%), Postives = 129/295 (43.73%), Query Frame = 1

Query:  382 KSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRIS---ESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            K++I+I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +  S    +N  G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:   43 KAQIEI--IPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 334

HSP 2 Score: 67.0106 bits (162), Expect = 3.121e-11
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:   51 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 131

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Match: Hr3 (gene:FBgn0000448 transcript:FBtr0330609)

HSP 1 Score: 98.2117 bits (243), Expect = 5.712e-21
Identity = 77/297 (25.93%), Postives = 130/297 (43.77%), Query Frame = 1

Query:  376 SNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRIS---ESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            S K++I+I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +  S    +N  G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:   41 SIKAQIEI--IPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 334

HSP 2 Score: 67.3958 bits (163), Expect = 2.833e-11
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:   51 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 131

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Match: Hr3 (gene:FBgn0000448 transcript:FBtr0088366)

HSP 1 Score: 97.0561 bits (240), Expect = 2.113e-20
Identity = 74/288 (25.69%), Postives = 125/288 (43.40%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRISESNSD-GNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +    SN++ G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:  255 IEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 541

HSP 2 Score: 67.781 bits (164), Expect = 2.905e-11
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:  260 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 340

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Match: rorca (RAR-related orphan receptor C a [Source:ZFIN;Acc:ZDB-GENE-990415-250])

HSP 1 Score: 95.1301 bits (235), Expect = 4.521e-20
Identity = 51/141 (36.17%), Postives = 77/141 (54.61%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRIS-ESNSDGNQRSISYSIPST 807
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q        L    + ISS    E+  +GN  S +YS  S+
Sbjct:    2 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSC-SRQRNCIIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERAGGLG---NGISSHTGDEAGENGNGHSRAYSRGSS 138

HSP 2 Score: 63.5438 bits (153), Expect = 4.905e-10
Identity = 38/122 (31.15%), Postives = 55/122 (45.08%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNK------SKIDISQIPCRVCGGKSSGF--HFGSLTCEGCKGFFR 489
            C++C   ++G H+G   CE CK FF+R   N        ++NC +++  R +C  CR QKCL +GM      FG  S K      +++   Q      GG  +G   H G    E   G  R
Sbjct:   10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCIIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERAGGLGNGISSHTGDEAGENGNGHSR 131

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Match: rorca (RAR-related orphan receptor C a [Source:ZFIN;Acc:ZDB-GENE-990415-250])

HSP 1 Score: 95.1301 bits (235), Expect = 5.541e-20
Identity = 51/141 (36.17%), Postives = 77/141 (54.61%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRIS-ESNSDGNQRSISYSIPST 807
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q        L    + ISS    E+  +GN  S +YS  S+
Sbjct:    3 ETQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSC-SRQRNCIIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERAGGLG---NGISSHTGDEAGENGNGHSRAYSRGSS 139

HSP 2 Score: 63.929 bits (154), Expect = 4.748e-10
Identity = 38/122 (31.15%), Postives = 55/122 (45.08%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNK------SKIDISQIPCRVCGGKSSGF--HFGSLTCEGCKGFFR 489
            C++C   ++G H+G   CE CK FF+R   N        ++NC +++  R +C  CR QKCL +GM      FG  S K      +++   Q      GG  +G   H G    E   G  R
Sbjct:   11 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCIIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERAGGLGNGISSHTGDEAGENGNGHSR 132

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Match: roraa (RAR-related orphan receptor A, paralog a [Source:NCBI gene;Acc:564951])

HSP 1 Score: 93.2041 bits (230), Expect = 1.773e-19
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 1

Query:  355 MKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:    1 MMYFVISAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 92

HSP 2 Score: 63.929 bits (154), Expect = 4.047e-10
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   18 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 98

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Match: rorab (RAR-related orphan receptor A, paralog b [Source:NCBI gene;Acc:554722])

HSP 1 Score: 92.4337 bits (228), Expect = 3.607e-19
Identity = 50/144 (34.72%), Postives = 76/144 (52.78%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSI--SYSIPSTPV 813
            K  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K +C+ID + +  C+ CR  +C+ VGMS+   + GR     +     E+  ++ +     T D      S +  ES + G    +  SY++ S+ V
Sbjct:    9 KAQIESIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQGTVSYSCPRQK-SCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLFAEVQKHRQQQQDDKTGD-----ESEKNQESQAPGEAEPLTPSYALSSSGV 146

HSP 2 Score: 62.7734 bits (151), Expect = 9.642e-10
Identity = 30/87 (34.48%), Postives = 48/87 (55.17%), Query Frame = 1

Query:  142 KMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            ++E+  C++C   ++G H+G   CE CK FF+R     ++     +K+C +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   11 QIESIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQGTVSYSCPRQKSCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 97

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Match: rorab (RAR-related orphan receptor A, paralog b [Source:NCBI gene;Acc:554722])

HSP 1 Score: 90.8929 bits (224), Expect = 1.301e-18
Identity = 49/141 (34.75%), Postives = 75/141 (53.19%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSI--SYSIPSTPV 813
            I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K +C+ID + +  C+ CR  +C+ VGMS+   + GR     +     E+  ++ +     T D      S +  ES + G    +  SY++ S+ V
Sbjct:   11 IESIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQGTVSYSCPRQK-SCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLFAEVQKHRQQQQDDKTGD-----ESEKNQESQAPGEAEPLTPSYALSSSGV 145

HSP 2 Score: 64.6994 bits (156), Expect = 2.520e-10
Identity = 32/93 (34.41%), Postives = 50/93 (53.76%), Query Frame = 1

Query:  124 FYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            F   Q ++E+  C++C   ++G H+G   CE CK FF+R     ++     +K+C +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:    4 FITKQSQIESIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQGTVSYSCPRQKSCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 96

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Match: ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component [Source:Xenbase;Acc:XB-GENE-5946075])

HSP 1 Score: 98.2117 bits (243), Expect = 4.768e-21
Identity = 93/439 (21.18%), Postives = 179/439 (40.77%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII-HYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVH------RNQSLLE-------------------------------VWNS----------------MMRHFDVHTC----ILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIP 1539
            I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+++GMS+   + GR     +     E+  H QN+        +   +    +S S S G    +S     + +       F  +PDG S  +  +L     +  +P  +      +   PVH       +Q+LL+                               VWN+                M +   +H       +V FAK++ GF +L  +D+  +++     ++L+ + R++    +       F      + +F       +L  + ++ + + +L+++ ++I L               F A   +  +  RL     +++L +   L           +   +Q  +C +DL+++++ K+P
Sbjct:    5 IEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSC-SRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQRDSLYAEVQKHQQNQEQ------VLARDTKDTVSRSYSTGTSSCLSDLEELSGLSDGLLFDFPLTPDGCSSYYSLEL----PLSTEPSPDPSHGTTLDELPVHYSLGLIEDQTLLDLNGTEIEYVSQNIIRSHLGTCQFTSDELSKMVWNAHSQEEVCSLQSKPCEMMWQLCAIHVSNAIQYVVEFAKRLDGFMELCQNDQIVLLKAGCLEVLLIRMTRAFNPSNNTVLFEGKFGG----IQMFRSLGCDDLLFAIFDLGQALCRLSLSDEEIAL---------------FTAAVLMSPDRPRLTESKKVQKLQDRIFLA----------LQKEIQKRHCSEDLLTKMISKLP 403

HSP 2 Score: 67.0106 bits (162), Expect = 6.072e-11
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  N     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSCSRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQR 90

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Match: ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component [Source:Xenbase;Acc:XB-GENE-5946075])

HSP 1 Score: 98.2117 bits (243), Expect = 5.026e-21
Identity = 93/442 (21.04%), Postives = 180/442 (40.72%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII-HYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVH------RNQSLLE-------------------------------VWNS----------------MMRHFDVHTC----ILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIP 1539
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+++GMS+   + GR     +     E+  H QN+        +   +    +S S S G    +S     + +       F  +PDG S  +  +L     +  +P  +      +   PVH       +Q+LL+                               VWN+                M +   +H       +V FAK++ GF +L  +D+  +++     ++L+ + R++    +       F      + +F       +L  + ++ + + +L+++ ++I L               F A   +  +  RL     +++L +   L           +   +Q  +C +DL+++++ K+P
Sbjct:    2 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSC-SRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQRDSLYAEVQKHQQNQEQ------VLARDTKDTVSRSYSTGTSSCLSDLEELSGLSDGLLFDFPLTPDGCSSYYSLEL----PLSTEPSPDPSHGTTLDELPVHYSLGLIEDQTLLDLNGTEIEYVSQNIIRSHLGTCQFTSDELSKMVWNAHSQEEVCSLQSKPCEMMWQLCAIHVSNAIQYVVEFAKRLDGFMELCQNDQIVLLKAGCLEVLLIRMTRAFNPSNNTVLFEGKFGG----IQMFRSLGCDDLLFAIFDLGQALCRLSLSDEEIAL---------------FTAAVLMSPDRPRLTESKKVQKLQDRIFLA----------LQKEIQKRHCSEDLLTKMISKLP 403

HSP 2 Score: 67.0106 bits (162), Expect = 6.270e-11
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  N     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSCSRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQR 90

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Match: ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component [Source:Xenbase;Acc:XB-GENE-5946075])

HSP 1 Score: 98.2117 bits (243), Expect = 5.848e-21
Identity = 93/442 (21.04%), Postives = 180/442 (40.72%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII-HYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVH------RNQSLLE-------------------------------VWNS----------------MMRHFDVHTC----ILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIP 1539
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+++GMS+   + GR     +     E+  H QN+        +   +    +S S S G    +S     + +       F  +PDG S  +  +L     +  +P  +      +   PVH       +Q+LL+                               VWN+                M +   +H       +V FAK++ GF +L  +D+  +++     ++L+ + R++    +       F      + +F       +L  + ++ + + +L+++ ++I L               F A   +  +  RL     +++L +   L           +   +Q  +C +DL+++++ K+P
Sbjct:    6 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSC-SRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQRDSLYAEVQKHQQNQEQ------VLARDTKDTVSRSYSTGTSSCLSDLEELSGLSDGLLFDFPLTPDGCSSYYSLEL----PLSTEPSPDPSHGTTLDELPVHYSLGLIEDQTLLDLNGTEIEYVSQNIIRSHLGTCQFTSDELSKMVWNAHSQEEVCSLQSKPCEMMWQLCAIHVSNAIQYVVEFAKRLDGFMELCQNDQIVLLKAGCLEVLLIRMTRAFNPSNNTVLFEGKFGG----IQMFRSLGCDDLLFAIFDLGQALCRLSLSDEEIAL---------------FTAAVLMSPDRPRLTESKKVQKLQDRIFLA----------LQKEIQKRHCSEDLLTKMISKLP 407

HSP 2 Score: 67.0106 bits (162), Expect = 6.295e-11
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  N     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   14 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSCSRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQR 94

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Match: ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component [Source:Xenbase;Acc:XB-GENE-5946075])

HSP 1 Score: 98.2117 bits (243), Expect = 6.396e-21
Identity = 93/439 (21.18%), Postives = 179/439 (40.77%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII-HYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVH------RNQSLLE-------------------------------VWNS----------------MMRHFDVHTC----ILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIP 1539
            I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+++GMS+   + GR     +     E+  H QN+        +   +    +S S S G    +S     + +       F  +PDG S  +  +L     +  +P  +      +   PVH       +Q+LL+                               VWN+                M +   +H       +V FAK++ GF +L  +D+  +++     ++L+ + R++    +       F      + +F       +L  + ++ + + +L+++ ++I L               F A   +  +  RL     +++L +   L           +   +Q  +C +DL+++++ K+P
Sbjct:   17 IEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSC-SRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQRDSLYAEVQKHQQNQEQ------VLARDTKDTVSRSYSTGTSSCLSDLEELSGLSDGLLFDFPLTPDGCSSYYSLEL----PLSTEPSPDPSHGTTLDELPVHYSLGLIEDQTLLDLNGTEIEYVSQNIIRSHLGTCQFTSDELSKMVWNAHSQEEVCSLQSKPCEMMWQLCAIHVSNAIQYVVEFAKRLDGFMELCQNDQIVLLKAGCLEVLLIRMTRAFNPSNNTVLFEGKFGG----IQMFRSLGCDDLLFAIFDLGQALCRLSLSDEEIAL---------------FTAAVLMSPDRPRLTESKKVQKLQDRIFLA----------LQKEIQKRHCSEDLLTKMISKLP 415

HSP 2 Score: 66.6254 bits (161), Expect = 7.723e-11
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  N     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   22 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSCSRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQR 102

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Match: ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component [Source:Xenbase;Acc:XB-GENE-5946075])

HSP 1 Score: 97.8265 bits (242), Expect = 7.868e-21
Identity = 93/439 (21.18%), Postives = 179/439 (40.77%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII-HYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVH------RNQSLLE-------------------------------VWNS----------------MMRHFDVHTC----ILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIP 1539
            I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+++GMS+   + GR     +     E+  H QN+        +   +    +S S S G    +S     + +       F  +PDG S  +  +L     +  +P  +      +   PVH       +Q+LL+                               VWN+                M +   +H       +V FAK++ GF +L  +D+  +++     ++L+ + R++    +       F      + +F       +L  + ++ + + +L+++ ++I L               F A   +  +  RL     +++L +   L           +   +Q  +C +DL+++++ K+P
Sbjct:   20 IEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSC-SRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQRDSLYAEVQKHQQNQEQ------VLARDTKDTVSRSYSTGTSSCLSDLEELSGLSDGLLFDFPLTPDGCSSYYSLEL----PLSTEPSPDPSHGTTLDELPVHYSLGLIEDQTLLDLNGTEIEYVSQNIIRSHLGTCQFTSDELSKMVWNAHSQEEVCSLQSKPCEMMWQLCAIHVSNAIQYVVEFAKRLDGFMELCQNDQIVLLKAGCLEVLLIRMTRAFNPSNNTVLFEGKFGG----IQMFRSLGCDDLLFAIFDLGQALCRLSLSDEEIAL---------------FTAAVLMSPDRPRLTESKKVQKLQDRIFLA----------LQKEIQKRHCSEDLLTKMISKLP 418

HSP 2 Score: 67.0106 bits (162), Expect = 6.623e-11
Identity = 30/81 (37.04%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  N     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   25 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNANYSCSRQRNCMIDRTNRNRCQHCRLQKCLELGMSRDAVKFGRMSKKQR 105

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Match: Pparg (peroxisome proliferator activated receptor gamma [Source:MGI Symbol;Acc:MGI:97747])

HSP 1 Score: 88.5817 bits (218), Expect = 2.865e-19
Identity = 44/91 (48.35%), Postives = 54/91 (59.34%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEI 678
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K     EI
Sbjct:  107 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 195

HSP 2 Score: 69.707 bits (169), Expect = 6.855e-13
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  109 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 179

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Match: Rora (RAR-related orphan receptor alpha [Source:MGI Symbol;Acc:MGI:104661])

HSP 1 Score: 92.4337 bits (228), Expect = 3.309e-19
Identity = 42/93 (45.16%), Postives = 62/93 (66.67%), Query Frame = 1

Query:  361 FFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:    2 YFVIAAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 91

HSP 2 Score: 63.929 bits (154), Expect = 4.098e-10
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   17 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 97

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Match: Pparg (peroxisome proliferator activated receptor gamma [Source:MGI Symbol;Acc:MGI:97747])

HSP 1 Score: 91.6633 bits (226), Expect = 6.122e-19
Identity = 74/257 (28.79%), Postives = 116/257 (45.14%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSD-GNQRSI------SYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNS-MMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K                         EISS I + N +  + R++      SY I S P+    + +  +        F    + ++ + +  +    K  H+T       +  + ++     R  +    I  Y AK +PGF +L L+D+ T+++  ++ I+   LA    +D
Sbjct:  107 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKL--------------------LAEISSDIDQLNPESADLRALAKHLYDSY-IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI----KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEY-AKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKD 335

HSP 2 Score: 70.8626 bits (172), Expect = 3.318e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  109 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 179

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Match: Pparg (peroxisome proliferator activated receptor gamma [Source:MGI Symbol;Acc:MGI:97747])

HSP 1 Score: 91.6633 bits (226), Expect = 6.122e-19
Identity = 74/257 (28.79%), Postives = 116/257 (45.14%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSD-GNQRSI------SYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNS-MMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K                         EISS I + N +  + R++      SY I S P+    + +  +        F    + ++ + +  +    K  H+T       +  + ++     R  +    I  Y AK +PGF +L L+D+ T+++  ++ I+   LA    +D
Sbjct:  107 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKL--------------------LAEISSDIDQLNPESADLRALAKHLYDSY-IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI----KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEY-AKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKD 335

HSP 2 Score: 70.8626 bits (172), Expect = 3.318e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  109 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 179

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Match: Pparg (peroxisome proliferator activated receptor gamma [Source:MGI Symbol;Acc:MGI:97747])

HSP 1 Score: 91.2781 bits (225), Expect = 1.083e-18
Identity = 74/257 (28.79%), Postives = 116/257 (45.14%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSD-GNQRSI------SYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNS-MMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CRVCG K+SGFH+G   CEGCKGFFRR   ++ KL      LNC I    +  C++CR+ +C+ VGMS    R GR P A K                         EISS I + N +  + R++      SY I S P+    + +  +        F    + ++ + +  +    K  H+T       +  + ++     R  +    I  Y AK +PGF +L L+D+ T+++  ++ I+   LA    +D
Sbjct:  137 IECRVCGDKASGFHYGVHACEGCKGFFRRT--IRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKL--------------------LAEISSDIDQLNPESADLRALAKHLYDSY-IKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKI----KFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEY-AKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKD 365

HSP 2 Score: 70.8626 bits (172), Expect = 3.009e-12
Identity = 33/75 (44.00%), Postives = 45/75 (60.00%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            C+VC   A+GFH+G + CE CK FF+R     +  K++   C  NC + K  R KC +CR+QKCL VGM    +R
Sbjct:  139 CRVCGDKASGFHYGVHACEGCKGFFRR----TIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIR 209

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Match: sp|P31396|HR3_DROME (Probable nuclear hormone receptor HR3 OS=Drosophila melanogaster OX=7227 GN=Hr3 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 2.664e-20
Identity = 76/295 (25.76%), Postives = 129/295 (43.73%), Query Frame = 1

Query:  382 KSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNR---------------NSSPSTLDIPYHEISSRIS---ESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAI----------KILQKPLLEA---------------EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLAR 1137
            K++I+I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+  ++ +                 +PS+ D  +H   +  S    +N  G      YS   TP  +      +   D  +    S +I+             +L K L EA                K   ++R   ++N    E+W             ++ FAK +PGF  LS  D+  +++   + + ++ ++R
Sbjct:   43 KAQIEI--IPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNK-QCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQMRAQSDAAPDSSVYDTQTPSSSDQLHHNNYNSYSGGYSNNEVGYGSPYGYSASVTPQQTMQYDISADYVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSR 334

HSP 2 Score: 67.0106 bits (162), Expect = 3.129e-10
Identity = 30/81 (37.04%), Postives = 47/81 (58.02%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  ++ +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:   51 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 131

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Match: sp|P41828|NHR23_CAEEL (Nuclear hormone receptor family member nhr-23 OS=Caenorhabditis elegans OX=6239 GN=nhr-23 PE=2 SV=2)

HSP 1 Score: 97.0561 bits (240), Expect = 1.727e-19
Identity = 47/98 (47.96%), Postives = 64/98 (65.31%), Query Frame = 1

Query:  355 MKFFGLRSNKSKI---DISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M F GL  NKS +    I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K NCV+D  ++  C++CR  +CI++GMS+   + GR
Sbjct:  141 MSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQK-NCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGR 237

HSP 2 Score: 69.3218 bits (168), Expect = 7.352e-11
Identity = 37/122 (30.33%), Postives = 65/122 (53.28%), Query Frame = 1

Query:   40 LDKNKVQSVILKTNTMLNNATFSS-PESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            +D N+V         + +N +F   PE+       ++E   C+VC   ++G H+G   CE CK FF+R  ++ +N +   +KNC ++++ R +C +CR +KC+ +GM      FG  S K +
Sbjct:  126 IDTNRVD----MAGILPDNMSFRGLPENKSLLVSAQIEVIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSIVNYQCPRQKNCVVDRVNRNRCQYCRLKKCIELGMSRDAVKFGRMSKKQR 243

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Match: sp|P49868|HR3_GALME (Probable nuclear hormone receptor HR3 OS=Galleria mellonella OX=7137 GN=HR3 PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.959e-19
Identity = 88/364 (24.18%), Postives = 148/364 (40.66%), Query Frame = 1

Query:  376 SNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIH----------------YQNRNSSPSTLDI------PYHEISSRISESNSDGNQRSISYS--------------------IPSTPVPXXXXXXXXXXPD--GHSQAFCSKLIEAIKILQKPLLEA--------EKLFHMTRFPVHRNQSLL-------EVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITK 1290
            +N  +  I  IPC+VCG KSSG H+G +TCEGCKGFFRR++      +C   K  CV+D  ++  C++CR  +C+K+GMS+   + GR     +     E+ +                Y  +  +PS+ D        Y    S +S     GN      S                    + ST              D  GH++   S      K+L K L EA        E +  M R P   ++ L        E+W             ++ FAK +PGF  LS  D+  +++   + + ++ L+R  + ++++   Y D      E +    P    ++  + + ++ I +L +T+
Sbjct:   96 ANSIRAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSTVVNYQCPRNKA-CVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRYHRAQMRAQTDAAPDSVYDAQQQTPSSSDQFHGHYNGYPGYRSPLSSYGYGGNAGPALTSNMNIQPQAPQQQPYDVSADYVDSTTAYEPKQTGGFLDADFIGHAEGDIS------KVLVKSLAEAHANTNPKLEYVHEMFRKPPDVSKLLFYNSMTYEEMWLDCADKLTGMIQNIIEFAKLIPGFMKLSQDDQILLLKSGSFELAIVRLSRLIDVNREQVL-YGDVVLPIRECVHARDPRDVTLVVGIFDAAKTIERLKLTE 451

HSP 2 Score: 67.0106 bits (162), Expect = 4.299e-10
Identity = 30/81 (37.04%), Postives = 46/81 (56.79%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C+VC   ++G H+G   CE CK FF+R  +  +N +    K C ++++ R +C +CR QKCL +GM      FG  S K +
Sbjct:  108 CKVCGDKSSGVHYGVITCEGCKGFFRRSQSTVVNYQCPRNKACVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQR 188

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Match: sp|O35507|PPARA_CAVPO (Peroxisome proliferator-activated receptor alpha OS=Cavia porcellus OX=10141 GN=PPARA PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 5.004e-19
Identity = 71/271 (26.20%), Postives = 114/271 (42.07%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMM---------------RHFDVHTCI-------LVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            I CR+CG K+SG+H+G   CEGCKGFFRR   ++ KL       +C I   ++  C++CR+H+C+ VGMS    R GR P + K     E++     +    T D+    ++ RI E+                              + H     +++I A K    PL           F +H  ++L     ++M               R F    C+       L  FAK +PGF  L L+D+ T+++  +Y  +   L+ +  +D
Sbjct:  100 IECRICGDKASGYHYGVHACEGCKGFFRRT--IRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEVLTCDRDSEGAETADL--KSLAKRIYEA---------------------------YLKNFHMNKVKARIILAGKTSSHPL-----------FVIHDMETLCTAEKTLMAKVVSDGIRDKEAEVRIFHCCQCVSVETVTNLTEFAKAIPGFASLDLNDQVTLLKYGVYEAIFTMLSSTMNKD 328

HSP 2 Score: 68.9366 bits (167), Expect = 7.508e-11
Identity = 37/97 (38.14%), Postives = 56/97 (57.73%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVV---CKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGL--RSNKSKIDISQIPC 414
            N  C++C   A+G+H+G + CE CK FF+R     +  K+V   C ++C ++K  R KC +CR+ KCL+VGM      FG   RS K+K+    + C
Sbjct:   99 NIECRICGDKASGYHYGVHACEGCKGFFRR----TIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEVLTC 191

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Match: sp|F1QLY4|RORAA_DANRE (Nuclear receptor ROR-alpha A OS=Danio rerio OX=7955 GN=roraa PE=2 SV=2)

HSP 1 Score: 93.2041 bits (230), Expect = 1.338e-18
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 1

Query:  355 MKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:    1 MMYFVISAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 92

HSP 2 Score: 63.929 bits (154), Expect = 3.055e-9
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   18 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 98

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Match: A0A564Y0P1 (Uncharacterized protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS1241 PE=3 SV=1)

HSP 1 Score: 260.381 bits (664), Expect = 2.376e-72
Identity = 128/234 (54.70%), Postives = 155/234 (66.24%), Query Frame = 1

Query:   28 SFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKK--NCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDI 723
            S Q  D +   S   ++   ++   F+SPESAFY+YQ +ME QLCQ+C  LAAGFHHGAYVCEACKKFF R+S     S   C    NC + K  R +C  CRY+KCL VGM    + + + ++DIS IPCRVCGG+SSGFHFG+LTCEGCKGFFRR E    +L CV GK NC I    +  CK CR+ RC++ GMSK GSRIGRQPNAVK HCA+EI   Q+ N  P   D 
Sbjct:  134 SRQMTDLDGSMSTPSRSTGGVSLPGFTSPESAFYQYQNRMEGQLCQICGELAAGFHHGAYVCEACKKFFMRHSLANGRSTTTCPSGGNCVIVKNSRGRCQQCRYKKCLEVGMSLKDMDA-QGELDISNIPCRVCGGRSSGFHFGALTCEGCKGFFRRTEETASRLVCVGGKDNCTITPRSRNVCKSCRFRRCLRAGMSKRGSRIGRQPNAVKFHCAIEIRQMQD-NGQPLASDF 365

HSP 2 Score: 98.2117 bits (243), Expect = 2.353e-17
Identity = 49/149 (32.89%), Postives = 85/149 (57.05%), Query Frame = 1

Query:  889 AIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNY 1335
            AI+ ++ P    +  F M+     +     +VW+ +M HF +H+  +V FAK +PGFN +SLS +  +V+ ++YS +LL L+R Y+  +D  +N+ DFS  E ++IL HFP   +++ H+    R   +LN+T  +    C I + + Y
Sbjct:  514 AIEFMRLPATYFKSRFDMSTVEPSQADDEHQVWDHVMNHFHLHSQQVVQFAKLIPGFNQMSLSARGHLVRASLYSEVLLMLSRDYDVTEDR-YNFLDFSPAERDIILRHFPIYNRVVEHLKISGRFFQQLNLTHTEFVYACAIGILRQY 661

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Match: A0A0R3TT29 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS10839 PE=4 SV=1)

HSP 1 Score: 256.529 bits (654), Expect = 4.178e-72
Identity = 124/209 (59.33%), Postives = 146/209 (69.86%), Query Frame = 1

Query:  103 FSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKK--NCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDI 723
            F+SPESAFY+YQ +ME QLCQ+C  LAAGFHHGAYVCEACKKFF R+S     S   C    NC + K  R +C  CRY+KCL VGM    + + + ++DIS IPCRVCGG+SSGFHFG+LTCEGCKGFFRR E    +L CV GK NC I    +  CK CR+ RC++ GMSK GSRIGRQPNAVK HCA+EI   Q+ N  P   D 
Sbjct:  153 FTSPESAFYQYQNRMEGQLCQICGELAAGFHHGAYVCEACKKFFMRHSLANGRSTTTCPSGGNCVIAKNSRGRCQQCRYKKCLEVGMSLKDMDA-QGELDISNIPCRVCGGRSSGFHFGALTCEGCKGFFRRTEETASRLVCVGGKDNCTITPRSRNVCKSCRFRRCLRAGMSKRGSRIGRQPNAVKFHCAIEIRQMQD-NGQPLATDF 359

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Match: A0A158QEI5 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS7453 PE=3 SV=1)

HSP 1 Score: 261.536 bits (667), Expect = 1.420e-71
Identity = 128/234 (54.70%), Postives = 155/234 (66.24%), Query Frame = 1

Query:   28 SFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKK--NCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDI 723
            S Q  D +   S   ++   ++   F+SPESAFY+YQ +ME QLCQ+C  LAAGFHHGAYVCEACKKFF R+S     S   C    NC + K  R +C  CRY+KCL VGM    + + + ++DIS IPCRVCGG+SSGFHFG+LTCEGCKGFFRR E    +L CV GK NC I    +  CK CR+ RC++ GMSK GSRIGRQPNAVK HCA+EI   Q+ N  P   D 
Sbjct:  134 SRQMTDLDGSMSTPSRSTGGVSLPGFTSPESAFYQYQNRMEGQLCQICGELAAGFHHGAYVCEACKKFFMRHSLANGRSTTTCPSGGNCVIVKNSRGRCQQCRYKKCLEVGMSLKDMDA-QGELDISNIPCRVCGGRSSGFHFGALTCEGCKGFFRRTEETASRLVCVGGKDNCTITPRSRNVCKSCRFRRCLRAGMSKRGSRIGRQPNAVKFHCAIEIRQMQD-NGQPLASDF 365

HSP 2 Score: 112.079 bits (279), Expect = 1.602e-21
Identity = 69/274 (25.18%), Postives = 131/274 (47.81%), Query Frame = 1

Query:  889 AIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLE--SFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQL 1704
            AI+ ++ P    +  F M+     +     +VW+ +M HF +H+  +V FAK +PGFN +SLS +  +V+ ++YS +LL L+R Y+  +D  +N+ DFS  E ++IL HFP   +++ H+    R   +LN+T  +    C I + + Y  L   ++   R +          ++  + +++ L+                                     ++KW +      + L E L   + E++ I  +L+R++P+L YP+LY EM+++
Sbjct:  514 AIEFMRLPATYFKSRFDMSTVEPSQADDEHQVWDHVMNHFHLHSQQVVQFAKLIPGFNQMSLSARGHLVRASLYSEVLLMLSRDYDVTEDR-YNFLDFSPAERDIILRHFPIYNRVVEHLKISGRFFQQLNLTHTEFVYACAIGILRQYYILANPAYTDARKLLLLARHSLLATMRSQTESQELV-------------------------------------DHKWNR-----LEALSEMLSSMSKEYRDIAQQLQRSRPDLRYPDLYAEMYEI 744

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Match: A0A3Q8VLE6 (2DBD nuclear receptor alpha OS=Echinococcus granulosus OX=6210 PE=2 SV=2)

HSP 1 Score: 260.381 bits (664), Expect = 2.367e-71
Identity = 120/194 (61.86%), Postives = 141/194 (72.68%), Query Frame = 1

Query:  103 FSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKK--NCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEI 678
            F+SPESAFY+YQ +ME QLCQ+C  LAAGFHHGAYVCEACKKFF R+S     S   C    NC + K  R +C  CRY+KCL VGM    + + + ++DIS IPCRVCGG+SSGFHFG+LTCEGCKGFFRR E    +L CV GK NC I    +  CK CR+ RC++ GMSK GSRIGRQPNAVK HCA+EI
Sbjct:  154 FTSPESAFYQYQNRMEGQLCQICGELAAGFHHGAYVCEACKKFFMRHSLANGRSTTTCPSGGNCVIAKSSRGRCQQCRYKKCLEVGMSLKDMDA-QGELDISNIPCRVCGGRSSGFHFGALTCEGCKGFFRRTEESASRLVCVGGKDNCTITPRSRNVCKTCRFRRCLRAGMSKRGSRIGRQPNAVKFHCAIEI 346

HSP 2 Score: 109.383 bits (272), Expect = 1.137e-20
Identity = 66/274 (24.09%), Postives = 132/274 (48.18%), Query Frame = 1

Query:  889 AIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLE--SFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQL 1704
            A++ ++ P    +  F M+     +     +VW+ +M HF +H+  +V FAK +PGFN +SLS +  +V+ ++YS +LL L+R Y+  +D  +N+ DFS  E +++L HFP   +++ H+    R   +LN+T  +   +C I + + Y  L   ++   R +          ++  + +++ L+                                     ++KW +      + + E L   + E++ I  +L+R++P+L YP+LY EM+++
Sbjct:  493 AMEFMRLPATYFKSRFDMSTIEPSQADDEHQVWDHVMNHFHLHSQQVVQFAKLIPGFNQMSLSARGHLVRASLYSEVLLMLSRDYDAAEDR-YNFLDFSPTERDIVLRHFPIYNRVVEHLKISGRFFQQLNLTHTEFVYVCAIGILRYYYILANPAYMDARKLLLLARHSLLATMRSQNESQELV-------------------------------------DHKWSR-----LEAMSEMLSSMSREYREIAQQLQRSRPDLRYPDLYVEMYEI 723

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Match: A0A068WW59 (Nuclear receptor 2DBD gamma OS=Echinococcus granulosus OX=6210 GN=EgrG_000379600 PE=3 SV=1)

HSP 1 Score: 260.381 bits (664), Expect = 3.934e-71
Identity = 120/194 (61.86%), Postives = 141/194 (72.68%), Query Frame = 1

Query:  103 FSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKK--NCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEI 678
            F+SPESAFY+YQ +ME QLCQ+C  LAAGFHHGAYVCEACKKFF R+S     S   C    NC + K  R +C  CRY+KCL VGM    + + + ++DIS IPCRVCGG+SSGFHFG+LTCEGCKGFFRR E    +L CV GK NC I    +  CK CR+ RC++ GMSK GSRIGRQPNAVK HCA+EI
Sbjct:  154 FTSPESAFYQYQNRMEGQLCQICGELAAGFHHGAYVCEACKKFFMRHSLANGRSTTTCPSGGNCVIAKSSRGRCQQCRYKKCLEVGMSLKDMDA-QGELDISNIPCRVCGGRSSGFHFGALTCEGCKGFFRRTEESASRLVCVGGKDNCTITPRSRNVCKACRFRRCLRAGMSKRGSRIGRQPNAVKFHCAIEI 346

HSP 2 Score: 108.612 bits (270), Expect = 1.888e-20
Identity = 62/244 (25.41%), Postives = 121/244 (49.59%), Query Frame = 1

Query:  979 EVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLE--SFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQL 1704
            +VW+ +M HF +H+  +V FAK +PGFN +SLS +  +V+ ++YS +LL L+R Y+  +D  +N+ DFS  E +++L HFP   +++ H+    R   +LN+T  +   +C I + + Y  L   ++   R +          ++  + +++ L+                                     ++KW +      + + E L   + E++ I  +L+R++P+L YP+LY EM+++
Sbjct:  545 QVWDHVMNHFHLHSQQVVQFAKLIPGFNQMSLSARGHLVRASLYSEVLLMLSRDYDAAEDR-YNFLDFSPTERDIVLRHFPIYNRVVEHLKISGRFFQQLNLTHTEFVYVCAIGILRYYYILANPAYTDARKLLLLARHSLLATMRSQNESQELV-------------------------------------DHKWSR-----LEAMSEMLSSMSREYREIAQQLQRSRPDLRYPDLYVEMYEI 745

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Match: rorca (nuclear receptor ROR-beta-like [Source:NCBI gene;Acc:103032914])

HSP 1 Score: 99.3673 bits (246), Expect = 1.818e-21
Identity = 49/136 (36.03%), Postives = 78/136 (57.35%), Query Frame = 1

Query:  385 SKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQN---RNSSPSTLDIPYHEISSRISESNSDGNQRS 783
            +K  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q    R S P  + +P   ++  I E+ + G+ R+
Sbjct:   16 AKTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSC-SRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERTSGPGGITLP-SRVNDDIGENGNGGHGRA 149

HSP 2 Score: 63.1586 bits (152), Expect = 6.693e-10
Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N        ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   25 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 105

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Match: rorca (nuclear receptor ROR-beta-like [Source:NCBI gene;Acc:103032914])

HSP 1 Score: 97.8265 bits (242), Expect = 6.009e-21
Identity = 48/135 (35.56%), Postives = 77/135 (57.04%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQN---RNSSPSTLDIPYHEISSRISESNSDGNQRS 783
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q    R S P  + +P   ++  I E+ + G+ R+
Sbjct:    2 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSC-SRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERTSGPGGITLP-SRVNDDIGENGNGGHGRA 134

HSP 2 Score: 63.1586 bits (152), Expect = 6.370e-10
Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N        ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 90

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Match: rorca (nuclear receptor ROR-beta-like [Source:NCBI gene;Acc:103032914])

HSP 1 Score: 96.6709 bits (239), Expect = 1.437e-20
Identity = 47/129 (36.43%), Postives = 75/129 (58.14%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQN---RNSSPSTLDIPYHEISSRISESNSDGNQRS 783
            IPC++CG KSSG H+G +TCEGCKGFFRR++       C S + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q    R S P  + +P   ++  I E+ + G+ R+
Sbjct:    5 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSC-SRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQSQERTSGPGGITLP-SRVNDDIGENGNGGHGRA 131

HSP 2 Score: 62.7734 bits (151), Expect = 8.228e-10
Identity = 29/81 (35.80%), Postives = 43/81 (53.09%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N        ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:    7 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNAMYSCSRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 87

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Match: roraa (nuclear receptor ROR-alpha [Source:NCBI gene;Acc:103045127])

HSP 1 Score: 92.8189 bits (229), Expect = 2.820e-19
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 1

Query:  355 MKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:   44 MMYFVISAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 135

HSP 2 Score: 63.929 bits (154), Expect = 3.807e-10
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   61 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 141

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Match: pparab (peroxisome proliferator-activated receptor alpha b [Source:ZFIN;Acc:ZDB-GENE-990415-211])

HSP 1 Score: 90.5077 bits (223), Expect = 1.165e-18
Identity = 72/262 (27.48%), Postives = 116/262 (44.27%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISE------SNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCI-------LVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            + CRVC  ++SG+H+G   CEGCKGFFRR   ++ KLE    + +C I   ++  C++CR+ +C+ VGMS    R GR P + K     EI+  +     P   D     ++ +I E      S +    R+I     +TP                   F    +E +++ ++ L+            V  +  LL   ++ +R F    C        L  FAK VPGF  L L+D+ T+++  +Y  +   LA    +D
Sbjct:  103 LECRVCSDRASGYHYGVHACEGCKGFFRRT--IRLKLEYDKCERHCKIQKKNRNKCQYCRFQKCLSVGMSHNAIRFGRMPQSEKLKLKAEILTGEKEVEDPRLAD--QKTLAKQIYEAYLKNFSMNKSKARTILTGKTNTP------------------PFVVHDMETLQLAEQTLVAKM---------VGTSGGLLN-KDAEVRIFHCCQCTSVETVTELTEFAKSVPGFCTLDLNDQVTLLKYGVYEALFAMLASCMNKD 332

HSP 2 Score: 71.633 bits (174), Expect = 1.254e-12
Identity = 32/75 (42.67%), Postives = 49/75 (65.33%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            N  C+VC+  A+G+H+G + CE CK FF+R    +L     C+++C ++K  R KC +CR+QKCL+VGM    +R
Sbjct:  102 NLECRVCSDRASGYHYGVHACEGCKGFFRRTIRLKLEYDK-CERHCKIQKKNRNKCQYCRFQKCLSVGMSHNAIR 175

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006486.1 (pep scaffold:Pmarinus_7.0:GL477261:3134:78930:1 gene:ENSPMAG00000005858.1 transcript:ENSPMAT00000006486.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.2705 bits (212), Expect = 4.350e-18
Identity = 90/395 (22.78%), Postives = 165/395 (41.77%), Query Frame = 1

Query:  352 GMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLA-RSYEEDKDEFFNYF--DFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIV 1527
            G  + G  S        Q  C +C  ++SG H+G LTC  CK FF+RA   +    C +G+ +C+ID   +  C  CR  +CI+ GM+ +G+R  ++   VK             N             ++    SNS       ++S P T  P                 F   LI  ++ ++  ++       M+ +   R+Q+   + +S+ R  D     +V +AK +PGF +L + D+  ++Q +   +M   ++ RS++    +   YF  D   DE  +       M ++   + ++S    KL +T ++   LC+    K  + L +        +       IS ++EL+     TE        +   L ++L+C  DL+S+++
Sbjct:   48 GFPYPGFTSPAQSSVPPQKACLICSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLC-AGRNDCIIDKIRRKNCPACRLRKCIQAGMT-LGARKLKKQGRVK-----------GENQRSPASSTATTSSATPQPSSNSTA---VTTFSPPPTGEPI----------------FSPTLIAILQAIEPEVV-------MSGYDNTRSQTTAYMLSSLNRLCDKQLVSIVKWAKSLPGFRNLHIDDQMVLIQYSWMGLMSFAMSWRSFQHTNSKLL-YFAPDLVFDETRM---QQSAMYQLCVEMRQVSEDFMKLQVTSEE--FLCM----KAILLLSTVPQEGLKSQGCFEEMRISYIRELNRTIARTEKNAVQCWQRFYQLTKLLDCMQDLVSKLL 393

HSP 2 Score: 59.3066 bits (142), Expect = 1.755e-9
Identity = 30/87 (34.48%), Postives = 45/87 (51.72%), Query Frame = 1

Query:  103 FSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF 363
            F+SP  +    Q     + C +C+  A+G H+G   C +CK FFKR    Q N     + +C ++KI R+ C  CR +KC+  GM  
Sbjct:   54 FTSPAQSSVPPQ-----KACLICSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRLRKCIQAGMTL 135

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Match: rorb (RAR-related orphan receptor B [Source:ZFIN;Acc:ZDB-GENE-061204-2])

HSP 1 Score: 86.2705 bits (212), Expect = 6.083e-18
Identity = 37/81 (45.68%), Postives = 54/81 (66.67%), Query Frame = 1

Query:  397 ISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   + NC+ID +++  C+ CR  +C+ +GMS+   + GR
Sbjct:   16 IEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQR-NCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGR 95

HSP 2 Score: 62.3882 bits (150), Expect = 2.327e-10
Identity = 34/101 (33.66%), Postives = 52/101 (51.49%), Query Frame = 1

Query:  100 TFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            T +S E A      ++E   C++C   ++G H+G   CE CK FF+R   N  +     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:    1 TCTSCEYAGLCVSAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 101

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Match: ESR2 (estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468])

HSP 1 Score: 76.2554 bits (186), Expect = 4.017e-15
Identity = 77/293 (26.28%), Postives = 127/293 (43.34%), Query Frame = 1

Query:  412 CRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSD---GNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAE--KLFHMTRFPVH--RNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLA-RSYEED------KDEFFNYFDFSK--------DEYEVILFHFPE 1224
            C VCG  SSG+H+G  TCEGCK FF+R+   K+   C +   +C ID + +  C+ CR  +C + GM + G       + +     ++ +    +N+S    +    +  +      SD   G  RS   ++P                  H+       +E + I+   LLEAE  KL  M R P       S++ ++  +     VH   +V +AKK+PGF +L L  K  +++++   +++  L  RS E+        D  F   D S+        D+   I+ HF E
Sbjct:    5 CSVCGDFSSGYHYGVWTCEGCKAFFKRSVQGKNNFVCPATN-HCTIDKTRRRRCQACRLRKCYEAGMIRDGC---HSRDRILLCMVIKSLKQLEKNASHGIRNTTSAQTPTGYRGFKSDARRGGIRSFGGAVP------------------HAH------VEGMGIIH-ILLEAEPPKLLCM-RSPGEPLTEASMMTLFTDLATKEMVH---IVSWAKKIPGFMELDLPVKIQLLENSWVEVLITGLIWRSMEQQDTLVFASDLVFTRADGSRMEGTMEIFDQVLAIVTHFRE 264

HSP 2 Score: 66.2402 bits (160), Expect = 7.848e-12
Identity = 28/69 (40.58%), Postives = 39/69 (56.52%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGM 357
             QLC VC   ++G+H+G + CE CK FFKR    + N       +C ++K  RR+C  CR +KC   GM
Sbjct:    2 TQLCSVCGDFSSGYHYGVWTCEGCKAFFKRSVQGKNNFVCPATNHCTIDKTRRRRCQACRLRKCYEAGM 70

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Match: nr1d2a (nuclear receptor subfamily 1, group D, member 2a [Source:ZFIN;Acc:ZDB-GENE-040504-1])

HSP 1 Score: 73.9442 bits (180), Expect = 7.692e-14
Identity = 40/98 (40.82%), Postives = 54/98 (55.10%), Query Frame = 1

Query:  412 CRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSS 705
            C+VCG  +SGFH+G   CEGCKGFFRR+     K +       C I  +++  C+ CR+ +C+ VGMSK   R GR P   K     E+ +  N  SS
Sbjct:  122 CKVCGDAASGFHYGVHACEGCKGFFRRSIQQNIKYKPCLKNETCPIVRANRNRCQHCRFKKCLSVGMSKDAVRFGRIPKREKLRLMEEVQNALNSASS 219

HSP 2 Score: 68.9366 bits (167), Expect = 2.521e-12
Identity = 42/124 (33.87%), Postives = 63/124 (50.81%), Query Frame = 1

Query:   55 VQSVILKTNTMLNNATFSSPESAF-YEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKN--CDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCR 417
            V S+  + +T+L +  +  P  A      I     LC+VC   A+GFH+G + CE CK FF+R     +  K  C KN  C + +  R +C  CR++KCL+VGM       +K  +   +IP R
Sbjct:   86 VTSLPARQDTVLQDHLYCPPAGASPGSVAINGVVLLCKVCGDAASGFHYGVHACEGCKGFFRRSIQQNIKYK-PCLKNETCPIVRANRNRCQHCRFKKCLSVGM-------SKDAVRFGRIPKR 201

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Match: ESR2 (estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3468])

HSP 1 Score: 72.0182 bits (175), Expect = 9.967e-14
Identity = 76/280 (27.14%), Postives = 117/280 (41.79%), Query Frame = 1

Query:  412 CRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSP--STLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAE--KLFHMTRFPVH--RNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLA-RSYEED------KDEFFNYFDFSKDEYEVILF 1212
            C VCG  SSG+H+G  TCEGCK FF+R+   K+   C +   +C ID + +  C+ CR  +C + GM        R    +   C+  +     R+S     +L  PY       S  +     +S+   I   P                            K LQ  LLEAE  KL  M R P       S++ ++  +     VH   +V +AKK+PGF +L L  K  +++++   +++  L  RS E+        D  F   D S+ E  + +F
Sbjct:   12 CSVCGDFSSGYHYGVWTCEGCKAFFKRSVQGKNNFVCPATN-HCTIDKTRRRRCQACRLRKCYEAGMI-------RDVPLLATACSSRLTRLARRHSPACHGSLAAPY-------STHSPSLPLQSLLLRIQLLP----------------------------KHLQAILLEAEPPKLLCM-RSPGEPLTEASMMTLFTDLATKEMVH---IVSWAKKIPGFMELDLPVKIQLLENSWVEVLITGLIWRSMEQQDTLVFASDLVFTRADGSRMEGTMEIF 244

HSP 2 Score: 66.2402 bits (160), Expect = 6.918e-12
Identity = 28/69 (40.58%), Postives = 39/69 (56.52%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGM 357
             QLC VC   ++G+H+G + CE CK FFKR    + N       +C ++K  RR+C  CR +KC   GM
Sbjct:    9 TQLCSVCGDFSSGYHYGVWTCEGCKAFFKRSVQGKNNFVCPATNHCTIDKTRRRRCQACRLRKCYEAGM 77

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Match: EDO39982 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8G8])

HSP 1 Score: 80.1073 bits (196), Expect = 4.588e-16
Identity = 67/263 (25.48%), Postives = 102/263 (38.78%), Query Frame = 1

Query:  412 CRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHY--------------QNRNSSPSTLDIPYHEISSRISESNSDGNQ--------RSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLA 1134
            C VC  K++G+H+G  TCEGCKGFF+R    + +  C  G  +C I+   +  C++CR+ +C+K GM K   R  R P     H +L+                  QN  SSP   D P   +      S  D N+        R     IP +PV           P+G   A                      F + +   +  Q L +V               + + K VPGF +L L D+ T+++ +   + +  LA
Sbjct:    4 CVVCNDKATGYHYGVFTCEGCKGFFKRTVQKQLEYTC-RGNQDCDINQHTRNRCQYCRFEKCVKSGMLKQAVRDDRTPGGRHRHASLQDHRQKKQKLQGKAPKELPQNGLSSPEGPDTPEGVV------SKEDENEFLIYIQQLRHDVDVIPDSPV---------KPPEGSPAAG---------------------FSVDKLMQYGYQELYQV---------------IQWGKNVPGFRELKLEDQITLLKTSFMDLNVFRLA 214

HSP 2 Score: 72.0182 bits (175), Expect = 1.976e-13
Identity = 30/77 (38.96%), Postives = 46/77 (59.74%), Query Frame = 1

Query:  157 LCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKS 387
            LC VCN  A G+H+G + CE CK FFKR    QL       ++CD+ +  R +C +CR++KC+  GM    +R +++
Sbjct:    3 LCVVCNDKATGYHYGVFTCEGCKGFFKRTVQKQLEYTCRGNQDCDINQHTRNRCQYCRFEKCVKSGMLKQAVRDDRT 79

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Match: EDO27017 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAF5])

HSP 1 Score: 77.7962 bits (190), Expect = 8.686e-16
Identity = 35/87 (40.23%), Postives = 54/87 (62.07%), Query Frame = 1

Query:  391 IDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNA 651
            +  SQ  C +CG +SSGFH+G  +CEGCK FF+R    + +  CV  K +C ID ++++ C++CR+ +C+ +GM K   R  R P  
Sbjct:    7 VTSSQRVCAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESK-SCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRAPGG 92

HSP 2 Score: 72.7886 bits (177), Expect = 3.348e-14
Identity = 31/85 (36.47%), Postives = 50/85 (58.82%), Query Frame = 1

Query:  133 YQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKS 387
            + +    ++C +C   ++GFH+G   CE CK FFKR    QL    V  K+C ++K  R +C +CR+QKCL +GM    +R +++
Sbjct:    5 FLVTSSQRVCAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESKSCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRA 89

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Match: EDO42195 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S286])

HSP 1 Score: 78.9518 bits (193), Expect = 9.059e-16
Identity = 35/84 (41.67%), Postives = 53/84 (63.10%), Query Frame = 1

Query:  400 SQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNA 651
            SQ  C +CG +SSGFH+G  +CEGCK FF+R    + +  CV  K +C ID ++++ C++CR+ +C+ +GM K   R  R P  
Sbjct:   10 SQRVCAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESK-SCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRAPGG 92

HSP 2 Score: 72.4034 bits (176), Expect = 1.224e-13
Identity = 31/85 (36.47%), Postives = 50/85 (58.82%), Query Frame = 1

Query:  133 YQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKS 387
            + +    ++C +C   ++GFH+G   CE CK FFKR    QL    V  K+C ++K  R +C +CR+QKCL +GM    +R +++
Sbjct:    5 FLVTSSQRVCAICGDRSSGFHYGVQSCEGCKSFFKRTVQKQLQYACVESKSCQIDKNNRIRCQYCRFQKCLALGMLKEAVREDRA 89

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Match: EDO37645 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF49])

HSP 1 Score: 78.5666 bits (192), Expect = 1.357e-15
Identity = 37/83 (44.58%), Postives = 51/83 (61.45%), Query Frame = 1

Query:  403 QIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNA 651
            Q+ C VCG KSSG H+G  TCEGCK FF+R+        C + + +C ID  H+  C++CR  +C+KVGM +   + GR P A
Sbjct:   25 QVECAVCGDKSSGKHYGVFTCEGCKSFFKRSVRRNLTYTCRASR-DCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRIPAA 106

HSP 2 Score: 68.9366 bits (167), Expect = 1.997e-12
Identity = 41/143 (28.67%), Postives = 66/143 (46.15%), Query Frame = 1

Query:   82 TMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCR---VCGGKSSGFHFGSLTCEGCKGFFRRAEP 501
            T     +  +PE +    Q++     C VC   ++G H+G + CE CK FFKR     L       ++C +++  R +C +CR +KCL VGM+   ++  + +I  +Q P +   + G    G   G     G      RAEP
Sbjct:    7 TTWTRDSTETPEDSEKNVQVE-----CAVCGDKSSGKHYGVFTCEGCKSFFKRSVRRNLTYTCRASRDCPIDQHHRNQCQYCRLKKCLKVGMRREAVQ--RGRIPAAQTPTQNAALPGINGDGSTNGHSYLSGFIALLLRAEP 142

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Match: EDO42277 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1X4])

HSP 1 Score: 74.3294 bits (181), Expect = 4.788e-14
Identity = 37/82 (45.12%), Postives = 49/82 (59.76%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNA 651
            I C VCG KSSG H+G  TCEGCK FF+R+        C  G  NC +D  ++  C++CR  +C+KVGM K   + GR P+ 
Sbjct:   30 IDCAVCGDKSSGKHYGVYTCEGCKSFFKRSIRRSLSYSC-RGVRNCPVDIQNRNQCQYCRLKKCLKVGMRKEAVQKGRIPST 110

HSP 2 Score: 63.1586 bits (152), Expect = 1.553e-10
Identity = 28/67 (41.79%), Postives = 39/67 (58.21%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMK 360
            C VC   ++G H+G Y CE CK FFKR     L+      +NC ++   R +C +CR +KCL VGM+
Sbjct:   32 CAVCGDKSSGKHYGVYTCEGCKSFFKRSIRRSLSYSCRGVRNCPVDIQNRNQCQYCRLKKCLKVGMR 98

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
Match: roraa (RAR related orphan receptor A [Source:NCBI gene;Acc:101167704])

HSP 1 Score: 93.5893 bits (231), Expect = 1.353e-19
Identity = 43/95 (45.26%), Postives = 63/95 (66.32%), Query Frame = 1

Query:  355 MKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGR 639
            M +F + + K++I+I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   K NC+ID + +  C+ CR  +C+ VGMS+   + GR
Sbjct:    1 MMYFVISAMKAQIEI--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQK-NCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR 92

HSP 2 Score: 63.929 bits (154), Expect = 3.017e-10
Identity = 33/83 (39.76%), Postives = 47/83 (56.63%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVC--KKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R  + Q N+   C  +KNC +++  R +C  CR QKCL VGM      FG  S K +
Sbjct:   18 CKICGDKSSGIHYGVITCEGCKGFFRR--SQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQR 98

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
Match: PPARA (peroxisome proliferator-activated receptor alpha [Source:NCBI gene;Acc:100304467])

HSP 1 Score: 92.4337 bits (228), Expect = 2.737e-19
Identity = 72/257 (28.02%), Postives = 116/257 (45.14%), Query Frame = 1

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISES------NSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAE-KLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCI-LVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            + CRVC  ++SG+H+G   CEGCKGFFRR   ++ KLE    +  C I   ++  C++CR+ +C+ VGMS    R GR P + K     E++  +     P   D     ++ +I ++       +    R++     STP      M      +   Q   +K++ +   L+    EAE ++FH  +                     V T   L  FAK VPGF  L L+D+ T+++  +Y  +   LA S  +D
Sbjct:  101 LECRVCADRASGYHYGVHACEGCKGFFRRT--IRLKLEYDKCERRCKIQKKNRNKCQYCRFQKCLAVGMSHNAIRFGRMPQSEKLKLKAEMVVGEREVEDPQLAD--QKSLAKQIYDAYLKNFNMTKAKARTVLTGKTSTPPFVIHDMETLQRAE---QTLVAKMVGSTGALKDR--EAEVRIFHCCQCT------------------SVETVTELTEFAKSVPGFAALDLNDQVTLLKYGVYEALFALLASSMNKD 330

HSP 2 Score: 70.4774 bits (171), Expect = 3.218e-12
Identity = 32/75 (42.67%), Postives = 46/75 (61.33%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            N  C+VC   A+G+H+G + CE CK FF+R    +L     C++ C ++K  R KC +CR+QKCL VGM    +R
Sbjct:  100 NLECRVCADRASGYHYGVHACEGCKGFFRRTIRLKLEYDK-CERRCKIQKKNRNKCQYCRFQKCLAVGMSHNAIR 173

[Close]

Query:  406 IPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISES------NSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAE-KLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCI-LVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEED 1152
            + CRVC  ++SG+H+G   CEGCKGFFRR   ++ KLE    +  C I   ++  C++CR+ +C+ VGMS    R GR P + K     E++  +     P   D     ++ +I ++       +    R++     STP      M      +   Q   +K++ +   L+    EAE ++FH  +                     V T   L  FAK VPGF  L L+D+ T+++  +Y  +   LA S  +D
Sbjct:  101 LECRVCADRASGYHYGVHACEGCKGFFRRT--IRLKLEYDKCERRCKIQKKNRNKCQYCRFQKCLAVGMSHNAIRFGRMPQSEKLKLKAEMVVGEREVEDPQLAD--QKSLAKQIYDAYLKNFNMTKAKARTVLTGKTSTPPFVIHDMETLQRAE---QTLVAKMVGSTGALKDR--EAEVRIFHCCQCT------------------SVETVTELTEFAKSVPGFAALDLNDQVTLLKYGVYEALFALLASSMNKD 330

HSP 2 Score: 70.4774 bits (171), Expect = 3.218e-12
Identity = 32/75 (42.67%), Postives = 46/75 (61.33%), Query Frame = 1

Query:  151 NQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLR 375
            N  C+VC   A+G+H+G + CE CK FF+R    +L     C++ C ++K  R KC +CR+QKCL VGM    +R
Sbjct:  100 NLECRVCADRASGYHYGVHACEGCKGFFRRTIRLKLEYDK-CERRCKIQKKNRNKCQYCRFQKCLAVGMSHNAIR 173

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
Match: rorb (RAR related orphan receptor B [Source:NCBI gene;Acc:101155775])

HSP 1 Score: 90.8929 bits (224), Expect = 9.834e-19
Identity = 44/140 (31.43%), Postives = 73/140 (52.14%), Query Frame = 1

Query:  388 KIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPST 807
            +  I  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q R            E  +R+  ++      ++++ I  T
Sbjct:    2 RAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQR-NCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQARLQEQRQQQTGEAEALARVYSTSLTNGLSTLNHEIGGT 140

HSP 2 Score: 63.929 bits (154), Expect = 3.155e-10
Identity = 29/81 (35.80%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  +     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   10 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 90

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
Match: rorb (RAR related orphan receptor B [Source:NCBI gene;Acc:101155775])

HSP 1 Score: 90.5077 bits (223), Expect = 1.125e-18
Identity = 45/143 (31.47%), Postives = 76/143 (53.15%), Query Frame = 1

Query:  379 NKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPST 807
            N  +I++  IPC++CG KSSG H+G +TCEGCKGFFRR++       C   + NC+ID +++  C+ CR  +C+ +GMS+   + GR     +     E+  +Q R            E  +R+  ++      ++++ I  T
Sbjct:    7 NTPQIEV--IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQR-NCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQARLQEQRQQQTGEAEALARVYSTSLTNGLSTLNHEIGGT 146

HSP 2 Score: 63.929 bits (154), Expect = 3.174e-10
Identity = 29/81 (35.80%), Postives = 44/81 (54.32%), Query Frame = 1

Query:  160 CQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKF----FGLRSNKSK 390
            C++C   ++G H+G   CE CK FF+R   N  +     ++NC +++  R +C  CR QKCL +GM      FG  S K +
Sbjct:   16 CKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQR 96

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Match: SMESG000007787.1 (SMESG000007787.1)

HSP 1 Score: 1137.87 bits (2942), Expect = 0.000e+0
Identity = 560/563 (99.47%), Postives = 560/563 (99.47%), Query Frame = 1

Query:   25 MSFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQLTAF 1713
            MSFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKS IDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEI S ISESNSDGNQRSISYSIPSTPVPSEWSMSFSSSPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQLTAF
Sbjct:    1 MSFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSNIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEICSSISESNSDGNQRSISYSIPSTPVPSEWSMSFSSSPDGHSQAFCSKLIEAIKILQKPLLEAEKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQLTAF 563

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Match: SMESG000008787.1 (SMESG000008787.1)

HSP 1 Score: 390.193 bits (1001), Expect = 5.616e-125
Identity = 236/558 (42.29%), Postives = 315/558 (56.45%), Query Frame = 1

Query:  100 TFSSPESAFYEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKN--CDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRAEPLKDKLECVSGKLN-CVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGNQRSISYSIPSTPVPXXXXXXXXXXPDGHSQA-------FCSKLI----EAIKILQKPLLEAEKLFHMTRFPVH---------RNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMFQL 1704
            TF+SPESAFY+YQ KME+QLCQVC   AAGFHHGAYVCEACKKFF R++ N     + C     C   K GR KC  CR++KC+++GM      +  SK DIS+IPCRVCGGKSSGFHFG+LTCEGCKGFFRR E  K  L C++G  + C+  SS +  CK CR++RC+ VGMSK GSRIGRQPNAVK HC LEI+          T D          SES +D ++R   +      V  +   +       H          F +K I    E   I +  L EA ++  +++  +          +  +L ++WN MM +FDVH+ ++V F K +PGFN   L  +R++VQDAMY IMLL LA+ Y+ D DE +NYFDFS  + EVIL +F   K+I  H++ ISR+++ L ++   I LLC+ EL KNY  L   +  + I  +   L W+ +    +NE      GN      ++   ++LN P           PK       QK   IF+ + + L E N EH  II ELK   PEL +PELY +MF +
Sbjct:  152 TFTSPESAFYDYQQKMESQLCQVCRESAAGFHHGAYVCEACKKFFMRHNLNSTKFTIPCPTGGQCAQLKTGRIKCQSCRFKKCVSIGMALQNPNNGNSKFDISKIPCRVCGGKSSGFHFGALTCEGCKGFFRRTESTKQHLACITGNNDCCLTGSSSRNLCKSCRFNRCLGVGMSKKGSRIGRQPNAVKFHCVLEIMQ--------RTCD-----QYDGASESANDNSKRKSVFHRAYRKVCQQSQKNLIRCSQNHFDKLKNDLSIFDTKDIFYSNEEKFIFESSLKEATRIIEISKANLQDLSSRQFSKKYLTLNDLWNYMMNNFDVHSAMIVQFVKAIPGFNKFELKSRRSLVQDAMYPIMLLKLAQDYKPDVDE-YNYFDFSLIDREVILNNFQSFKRITDHLLSISRMVHSLQLSSYPISLLCVTELMKNYHLLSDEEEGKRILNQAKSLLWLFL---ENNEVEDNTIGN------LTKQTEMLNLP-----------PKNY-----QKYIKIFEEMPKLLSEMNSEHLKIIQELKYLHPELLFPELYIDMFNI 670

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Match: SMESG000020242.1 (SMESG000020242.1)

HSP 1 Score: 205.682 bits (522), Expect = 2.179e-55
Identity = 129/293 (44.03%), Postives = 165/293 (56.31%), Query Frame = 1

Query:   28 SFQKLDKNKVQSVILKTNTMLNNATFSSPESAF-------YEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKN--CDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRA--EPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII---------HYQNRNS-SPSTLD-------IPYHEISSRISESNSDGN--QRSISYSIPSTPVP 816
            S+ K D++ V    LK  T  N  +  +P SA        Y Y+   E + C VC  ++AGFH  A+VCEACKKFF R S     +K  C KN  C++ K  R  C +CR+QKCL++GM   G   N++  DIS IPCRVCG +SSGFHFG++TCEGCKGFFRR   E    K  C +G  NCVI+ + +  CK CRY +C+ +GMSK GSRIGRQPNA+KH CA EI          H+ N NS S    D       +P H  S+ +S  N D N       Y   + P+P
Sbjct:  211 SYLKYDQSPVGWYKLKEETRPN-CSVPTPLSADQLSNGYDYNYREMKEKRKCDVCGDVSAGFHCSAFVCEACKKFFIRSSKGDSYTKYSCTKNNNCEIVKDTRTHCQYCRFQKCLHLGMTLPGANLNQN-TDISLIPCRVCGAQSSGFHFGAITCEGCKGFFRRTINERENQKYTCRNGG-NCVINLATRNNCKSCRYKKCLAMGMSKEGSRIGRQPNAIKHMCAKEISQIRAGLALNHFSNNNSHSIGHTDSGMIQAYLPNHLSSAIMSTMNLDFNLTNGQTRYQQTTAPLP 500

HSP 2 Score: 106.301 bits (264), Expect = 3.072e-23
Identity = 75/239 (31.38%), Postives = 111/239 (46.44%), Query Frame = 1

Query:  982 VWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMF 1698
            VW+ MM+HF  H   ++ FAK VPGF +L  +D + +VQ+ MY I+L+ L+R +    DE FNYF+FS  E E+IL  F    KI  HVM+  R+I   N+      L+C +EL K        ++     +  V   +   +  L  +  +TE G+                               T+N+    L  IF VL +       EHQ  +  L+ +KP L +P LYT+MF
Sbjct:  679 VWDVMMQHFQAHAIQVIKFAKAVPGFKELFHNDMKVLVQEGMYPIILVQLSRDFNLATDE-FNYFNFSNKEKEIILTRFAIFNKIADHVMKSGRLIKLKNLDDTIFSLICYVELVKG-------ESCSVFDRNKVNQMYQYSMNAL--KLYMTEIGS-------------------------------TQNEIDSVLE-IFPVLSKMTH----EHQEAVMMLRTSKPHLKFPNLYTQMF 871

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Match: SMESG000020242.1 (SMESG000020242.1)

HSP 1 Score: 205.682 bits (522), Expect = 2.254e-55
Identity = 129/293 (44.03%), Postives = 165/293 (56.31%), Query Frame = 1

Query:   28 SFQKLDKNKVQSVILKTNTMLNNATFSSPESAF-------YEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKN--CDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRA--EPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII---------HYQNRNS-SPSTLD-------IPYHEISSRISESNSDGN--QRSISYSIPSTPVP 816
            S+ K D++ V    LK  T  N  +  +P SA        Y Y+   E + C VC  ++AGFH  A+VCEACKKFF R S     +K  C KN  C++ K  R  C +CR+QKCL++GM   G   N++  DIS IPCRVCG +SSGFHFG++TCEGCKGFFRR   E    K  C +G  NCVI+ + +  CK CRY +C+ +GMSK GSRIGRQPNA+KH CA EI          H+ N NS S    D       +P H  S+ +S  N D N       Y   + P+P
Sbjct:  229 SYLKYDQSPVGWYKLKEETRPN-CSVPTPLSADQLSNGYDYNYREMKEKRKCDVCGDVSAGFHCSAFVCEACKKFFIRSSKGDSYTKYSCTKNNNCEIVKDTRTHCQYCRFQKCLHLGMTLPGANLNQN-TDISLIPCRVCGAQSSGFHFGAITCEGCKGFFRRTINERENQKYTCRNGG-NCVINLATRNNCKSCRYKKCLAMGMSKEGSRIGRQPNAIKHMCAKEISQIRAGLALNHFSNNNSHSIGHTDSGMIQAYLPNHLSSAIMSTMNLDFNLTNGQTRYQQTTAPLP 518

HSP 2 Score: 106.301 bits (264), Expect = 3.217e-23
Identity = 75/239 (31.38%), Postives = 111/239 (46.44%), Query Frame = 1

Query:  982 VWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMF 1698
            VW+ MM+HF  H   ++ FAK VPGF +L  +D + +VQ+ MY I+L+ L+R +    DE FNYF+FS  E E+IL  F    KI  HVM+  R+I   N+      L+C +EL K        ++     +  V   +   +  L  +  +TE G+                               T+N+    L  IF VL +       EHQ  +  L+ +KP L +P LYT+MF
Sbjct:  697 VWDVMMQHFQAHAIQVIKFAKAVPGFKELFHNDMKVLVQEGMYPIILVQLSRDFNLATDE-FNYFNFSNKEKEIILTRFAIFNKIADHVMKSGRLIKLKNLDDTIFSLICYVELVKG-------ESCSVFDRNKVNQMYQYSMNAL--KLYMTEIGS-------------------------------TQNEIDSVLE-IFPVLSKMTH----EHQEAVMMLRTSKPHLKFPNLYTQMF 889

[Close]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Match: SMESG000020242.1 (SMESG000020242.1)

HSP 1 Score: 205.297 bits (521), Expect = 2.919e-55
Identity = 129/293 (44.03%), Postives = 165/293 (56.31%), Query Frame = 1

Query:   28 SFQKLDKNKVQSVILKTNTMLNNATFSSPESAF-------YEYQIKMENQLCQVCNCLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKN--CDLEKIGRRKCSFCRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGCKGFFRRA--EPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIGSRIGRQPNAVKHHCALEII---------HYQNRNS-SPSTLD-------IPYHEISSRISESNSDGN--QRSISYSIPSTPVP 816
            S+ K D++ V    LK  T  N  +  +P SA        Y Y+   E + C VC  ++AGFH  A+VCEACKKFF R S     +K  C KN  C++ K  R  C +CR+QKCL++GM   G   N++  DIS IPCRVCG +SSGFHFG++TCEGCKGFFRR   E    K  C +G  NCVI+ + +  CK CRY +C+ +GMSK GSRIGRQPNA+KH CA EI          H+ N NS S    D       +P H  S+ +S  N D N       Y   + P+P
Sbjct:  211 SYLKYDQSPVGWYKLKEETRPN-CSVPTPLSADQLSNGYDYNYREMKEKRKCDVCGDVSAGFHCSAFVCEACKKFFIRSSKGDSYTKYSCTKNNNCEIVKDTRTHCQYCRFQKCLHLGMTLPGANLNQN-TDISLIPCRVCGAQSSGFHFGAITCEGCKGFFRRTINERENQKYTCRNGG-NCVINLATRNNCKSCRYKKCLAMGMSKEGSRIGRQPNAIKHMCAKEISQIRAGLALNHFSNNNSHSIGHTDSGMIQAYLPNHLSSAIMSTMNLDFNLTNGQTRYQQTTAPLP 500

HSP 2 Score: 105.916 bits (263), Expect = 3.372e-23
Identity = 75/239 (31.38%), Postives = 111/239 (46.44%), Query Frame = 1

Query:  982 VWNSMMRHFDVHTCILVYFAKKVPGFNDLSLSDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPEMKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIHKEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQIVFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPYPELYTEMF 1698
            VW+ MM+HF  H   ++ FAK VPGF +L  +D + +VQ+ MY I+L+ L+R +    DE FNYF+FS  E E+IL  F    KI  HVM+  R+I   N+      L+C +EL K        ++     +  V   +   +  L  +  +TE G+                               T+N+    L  IF VL +       EHQ  +  L+ +KP L +P LYT+MF
Sbjct:  685 VWDVMMQHFQAHAIQVIKFAKAVPGFKELFHNDMKVLVQEGMYPIILVQLSRDFNLATDE-FNYFNFSNKEKEIILTRFAIFNKIADHVMKSGRLIKLKNLDDTIFSLICYVELVKG-------ESCSVFDRNKVNQMYQYSMNAL--KLYMTEIGS-------------------------------TQNEIDSVLE-IFPVLSKMTH----EHQEAVMMLRTSKPHLKFPNLYTQMF 877

The following BLAST results are available for this feature:

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Yeast
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RORA	1.449e-19	45.26	RAR related orphan receptor A [Source:HGNC Symbol;...	[more]
PPARG	1.491e-19	28.13	peroxisome proliferator activated receptor gamma [...	[more]
PPARG	3.545e-19	28.40	peroxisome proliferator activated receptor gamma [...	[more]
PPARG	7.034e-19	48.35	peroxisome proliferator activated receptor gamma [...	[more]
PPARG	7.295e-19	48.35	peroxisome proliferator activated receptor gamma [...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nhr-23	1.082e-20	47.96	Nuclear hormone receptor family member nhr-23 [So...	[more]
nhr-23	1.102e-20	47.96	Nuclear hormone receptor family member nhr-23 [So...	[more]
nhr-23	1.358e-20	47.96	Nuclear hormone receptor family member nhr-23 [So...	[more]
nhr-23	7.216e-19	49.38	Nuclear hormone receptor family member nhr-23 [So...	[more]
nhr-23	7.637e-19	49.38	Nuclear hormone receptor family member nhr-23 [So...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hr3	2.251e-21	25.60	gene:FBgn0000448 transcript:FBtr0112799	[more]
Hr3	2.658e-21	25.76	gene:FBgn0000448 transcript:FBtr0088368	[more]
Hr3	2.658e-21	25.76	gene:FBgn0000448 transcript:FBtr0306345	[more]
Hr3	5.712e-21	25.93	gene:FBgn0000448 transcript:FBtr0330609	[more]
Hr3	2.113e-20	25.69	gene:FBgn0000448 transcript:FBtr0088366	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rorca	4.521e-20	36.17	RAR-related orphan receptor C a [Source:ZFIN;Acc:Z...	[more]
rorca	5.541e-20	36.17	RAR-related orphan receptor C a [Source:ZFIN;Acc:Z...	[more]
roraa	1.773e-19	45.26	RAR-related orphan receptor A, paralog a [Source:N...	[more]
rorab	3.607e-19	34.72	RAR-related orphan receptor A, paralog b [Source:N...	[more]
rorab	1.301e-18	34.75	RAR-related orphan receptor A, paralog b [Source:N...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctr9	4.768e-21	21.18	CTR9 homolog, Paf1/RNA polymerase II complex compo...	[more]
ctr9	5.026e-21	21.04	CTR9 homolog, Paf1/RNA polymerase II complex compo...	[more]
ctr9	5.848e-21	21.04	CTR9 homolog, Paf1/RNA polymerase II complex compo...	[more]
ctr9	6.396e-21	21.18	CTR9 homolog, Paf1/RNA polymerase II complex compo...	[more]
ctr9	7.868e-21	21.18	CTR9 homolog, Paf1/RNA polymerase II complex compo...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pparg	2.865e-19	48.35	peroxisome proliferator activated receptor gamma [...	[more]
Rora	3.309e-19	45.16	RAR-related orphan receptor alpha [Source:MGI Symb...	[more]
Pparg	6.122e-19	28.79	peroxisome proliferator activated receptor gamma [...	[more]
Pparg	6.122e-19	28.79	peroxisome proliferator activated receptor gamma [...	[more]
Pparg	1.083e-18	28.79	peroxisome proliferator activated receptor gamma [...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P31396\|HR3_DROME	2.664e-20	25.76	Probable nuclear hormone receptor HR3 OS=Drosophil...	[more]
sp\|P41828\|NHR23_CAEEL	1.727e-19	47.96	Nuclear hormone receptor family member nhr-23 OS=C...	[more]
sp\|P49868\|HR3_GALME	1.959e-19	24.18	Probable nuclear hormone receptor HR3 OS=Galleria ...	[more]
sp\|O35507\|PPARA_CAVPO	5.004e-19	26.20	Peroxisome proliferator-activated receptor alpha O...	[more]
sp\|F1QLY4\|RORAA_DANRE	1.338e-18	45.26	Nuclear receptor ROR-alpha A OS=Danio rerio OX=795...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A564Y0P1	2.376e-72	54.70	Uncharacterized protein (Fragment) OS=Hymenolepis ...	[more]
A0A0R3TT29	4.178e-72	59.33	Uncharacterized protein OS=Rodentolepis nana OX=10...	[more]
A0A158QEI5	1.420e-71	54.70	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A3Q8VLE6	2.367e-71	61.86	2DBD nuclear receptor alpha OS=Echinococcus granul...	[more]
A0A068WW59	3.934e-71	61.86	Nuclear receptor 2DBD gamma OS=Echinococcus granul...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rorca	1.818e-21	36.03	nuclear receptor ROR-beta-like [Source:NCBI gene;A...	[more]
rorca	6.009e-21	35.56	nuclear receptor ROR-beta-like [Source:NCBI gene;A...	[more]
rorca	1.437e-20	36.43	nuclear receptor ROR-beta-like [Source:NCBI gene;A...	[more]
roraa	2.820e-19	45.26	nuclear receptor ROR-alpha [Source:NCBI gene;Acc:1...	[more]
pparab	1.165e-18	27.48	peroxisome proliferator-activated receptor alpha b...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000006486.1	4.350e-18	22.78	pep scaffold:Pmarinus_7.0:GL477261:3134:78930:1 ge...	[more]
rorb	6.083e-18	45.68	RAR-related orphan receptor B [Source:ZFIN;Acc:ZDB...	[more]
ESR2	4.017e-15	26.28	estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3...	[more]
nr1d2a	7.692e-14	40.82	nuclear receptor subfamily 1, group D, member 2a [...	[more]
ESR2	9.967e-14	27.14	estrogen receptor 2 [Source:HGNC Symbol;Acc:HGNC:3...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39982	4.588e-16	25.48	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27017	8.686e-16	40.23	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42195	9.059e-16	41.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37645	1.357e-15	44.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42277	4.788e-14	45.12	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
roraa	1.353e-19	45.26	RAR related orphan receptor A [Source:NCBI gene;Ac...	[more]
PPARA	2.737e-19	28.02	peroxisome proliferator-activated receptor alpha [...	[more]
PPARA	2.737e-19	28.02	peroxisome proliferator-activated receptor alpha [...	[more]
rorb	9.834e-19	31.43	RAR related orphan receptor B [Source:NCBI gene;Ac...	[more]
rorb	1.125e-18	31.47	RAR related orphan receptor B [Source:NCBI gene;Ac...	[more]

BLAST of Nuclear receptor 2DBD gamma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000007787.1	0.000e+0	99.47	SMESG000007787.1	[more]
SMESG000008787.1	5.616e-125	42.29	SMESG000008787.1	[more]
SMESG000020242.1	2.179e-55	44.03	SMESG000020242.1	[more]
SMESG000020242.1	2.254e-55	44.03	SMESG000020242.1	[more]
SMESG000020242.1	2.919e-55	44.03	SMESG000020242.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001785 ID=SMED30001785|Name=Nuclear receptor 2DBD gamma|organism=Schmidtea mediterranea sexual|type=transcript|length=2370bp
CAATTAAATTTTACTTTATTTTAGATGTCATTTCAAAAACTAGATAAAAA
TAAAGTTCAGTCAGTTATTCTCAAGACAAATACAATGCTTAACAACGCAA
CATTTTCTAGTCCAGAATCTGCATTTTATGAGTATCAAATTAAAATGGAA
AACCAACTTTGCCAAGTATGTAATTGCTTAGCTGCAGGATTTCATCACGG
AGCTTATGTTTGTGAAGCGTGCAAAAAATTTTTCAAGCGCTATTCAACTA
ATCAGTTGAATTCGAAAGTAGTTTGCAAAAAGAATTGCGATTTGGAGAAA
ATTGGCAGGAGGAAATGTTCGTTTTGTCGTTATCAGAAATGTTTGAATGT
AGGAATGAAGTTTTTCGGATTAAGATCAAATAAATCCAAAATCGACATAT
CACAAATTCCGTGCCGTGTTTGCGGAGGAAAATCTTCTGGGTTTCATTTC
GGATCTTTAACCTGTGAAGGATGTAAGGGTTTTTTTCGTCGAGCCGAGCC
ACTGAAAGATAAATTGGAATGCGTGAGCGGAAAACTGAATTGCGTGATTG
ATTCCTCCCATAAAATGCCTTGTAAATGGTGTAGATATCACCGTTGTATT
AAGGTTGGGATGTCGAAAATTGGTAGTCGGATAGGTCGGCAGCCAAATGC
TGTCAAGCATCATTGCGCTCTGGAAATTATCCATTATCAGAATAGAAATT
CATCGCCGAGCACCTTGGATATTCCATATCACGAAATCAGTTCTAGAATT
TCTGAATCCAACTCTGATGGAAATCAGCGTTCAATAAGCTACAGTATTCC
TTCAACTCCAGTTCCATCTGAGTGGTCTATGAGTTTTTCATCGTCTCCCG
ATGGTCATTCACAGGCATTTTGTTCAAAATTAATTGAAGCAATTAAAATA
CTACAAAAGCCGTTATTAGAAGCAGAAAAGTTATTCCACATGACTCGTTT
CCCAGTTCACAGGAATCAATCTCTTCTCGAAGTGTGGAATAGCATGATGC
GGCATTTTGACGTTCACACTTGTATTTTAGTGTATTTTGCGAAAAAAGTT
CCTGGGTTCAATGATCTATCGCTGTCCGACAAACGGACAATGGTTCAGGA
TGCTATGTATTCGATTATGTTGCTCAATTTGGCACGTTCGTATGAGGAGG
ACAAAGACGAATTTTTCAATTATTTTGACTTTTCCAAAGATGAATACGAA
GTGATATTGTTTCACTTTCCTGAAATGAAAAAGATCTTAGCACATGTTAT
GGAAATAAGCAGAATAATCTATAAACTGAATATCACTAAAGATCAGATCG
GACTTCTTTGTATTATTGAATTGTCTAAAAATTATATAAATTTGGAATCA
TTTGATGCCGTTCGAACGATACACAAGGAAGTTGTGCGATTATTTTGGAT
ATCAATTTTAAAAGAATTGGACAATGAAGCATTGTTGACAGAACCAGGAA
ACCCTCCGTCTTTACCTCAAATGTCGGTGCTACTACAAGTGTTAAACTGT
CCCGATGATCTGATCAGTCAAATTGTATTTAAAATACCGAAATGTACCGA
AAATAAATGGTGTCAAAAGTTGCACATAATTTTTAAAGTGCTCGGTGAAA
AGTTACAAGAATTCAATATTGAACATCAAATGATAATCGATGAATTGAAA
AGAAATAAGCCTGAATTGCCATATCCGGAACTTTACACTGAAATGTTTCA
ACTGACTGCTTTTTAATCCATGATTTTTTTTCTTGGAATTAGTCGATGTT
TCAATTGAATTGTGTTTCGATCAAATAATTTTGTATAAATTTATAAATGT
TTTTGCAATGTCGCTCTTCGTTATTAATTCGTGTTTAAACGTATTTGATT
GGTTGATTTATTTCTCGTGCTAAATTTATAATTGTTTTAAAAAGATTTTA
TTGGTCGATTTTATTAAGCGTGTTGGAAGGTTATGTTTTGATAAATGTTG
AACAATAAAACATTTTTTTTGATAGTCACTGAATTTTCATAATGCCTTCT
TTGTGACAACGAAAAGAGACATCAGAAAAAGAGATACAGAGAAAATGTTA
TCAGTTTTTATTTCGAGCTCGGTGGTAAAGAACGTTGCAGCTCTTAATTG
TTCAATCATTACTTTCATTTCATTTGTTATTAAAATCGGGAAATGCTTTC
AACCTTTTATGACCTGGACTACATTTTCGCTTTAAATAGTATTTTTTTCA
GGCAAAAGGGACCTGGAATTTCTAACAAAACTGTATAAAGGAGTACAATA
AGTTGATGTGTATGATTAATTTGTACTTTTTATAGATGTAAAAAAAATAG
ACTTTCAATGTTTTAAAGCGATCTTGTAAAGTGAAAATTATTTTTGTGAA
ATGTTGTTAGACATGACAGG

protein sequence of SMED30001785-orf-1

>SMED30001785-orf-1 ID=SMED30001785-orf-1|Name=SMED30001785-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=564bp
MSFQKLDKNKVQSVILKTNTMLNNATFSSPESAFYEYQIKMENQLCQVCN
CLAAGFHHGAYVCEACKKFFKRYSTNQLNSKVVCKKNCDLEKIGRRKCSF
CRYQKCLNVGMKFFGLRSNKSKIDISQIPCRVCGGKSSGFHFGSLTCEGC
KGFFRRAEPLKDKLECVSGKLNCVIDSSHKMPCKWCRYHRCIKVGMSKIG
SRIGRQPNAVKHHCALEIIHYQNRNSSPSTLDIPYHEISSRISESNSDGN
QRSISYSIPSTPVPSEWSMSFSSSPDGHSQAFCSKLIEAIKILQKPLLEA
EKLFHMTRFPVHRNQSLLEVWNSMMRHFDVHTCILVYFAKKVPGFNDLSL
SDKRTMVQDAMYSIMLLNLARSYEEDKDEFFNYFDFSKDEYEVILFHFPE
MKKILAHVMEISRIIYKLNITKDQIGLLCIIELSKNYINLESFDAVRTIH
KEVVRLFWISILKELDNEALLTEPGNPPSLPQMSVLLQVLNCPDDLISQI
VFKIPKCTENKWCQKLHIIFKVLGEKLQEFNIEHQMIIDELKRNKPELPY
PELYTEMFQLTAF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0042025	host cell nucleus
GO:0005634	nucleus

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000074	oocyte
PLANA:0000231	vitelline gland
PLANA:0002109	X1 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035500	NHR-like_dom_sf
IPR001723	Nuclear_hrmn_rcpt
IPR001628	Znf_hrmn_rcpt
IPR013088	Znf_NHR/GATA
IPR000536	Nucl_hrmn_rcpt_lig-bd

Vocabulary: **molecular function**
Term	Definition
GO:0003707	steroid hormone receptor activity
GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding
GO:0008270	zinc ion binding
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated
GO:0043401	steroid hormone mediated signaling pathway
GO:0006351	transcription, DNA-templated

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001723	Nuclear hormone receptor	PRINTS	PR00398	STRDHORMONER	coord: 418..433 score: 24.67 coord: 192..202 score: 39.39 coord: 327..348 score: 32.61 coord: 348..364 score: 21.33
IPR001628	Zinc finger, nuclear hormone receptor-type	PRINTS	PR00047	STROIDFINGER	coord: 146..161 score: 57.09 coord: 130..146 score: 48.69 coord: 180..188 score: 36.39 coord: 188..196 score: 44.47
IPR001628	Zinc finger, nuclear hormone receptor-type	SMART	SM00399	c4gold	coord: 127..199 e-value: 2.0E-25 score: 100.4 coord: 43..114 e-value: 1.6E-16 score: 70.9
IPR001628	Zinc finger, nuclear hormone receptor-type	PFAM	PF00105	zf-C4	coord: 129..198 e-value: 2.4E-22 score: 79.1 coord: 44..112 e-value: 6.2E-18 score: 65.0
IPR001628	Zinc finger, nuclear hormone receptor-type	PROSITE	PS51030	NUCLEAR_REC_DBD_2	coord: 127..203 score: 16.311
IPR001628	Zinc finger, nuclear hormone receptor-type	PROSITE	PS51030	NUCLEAR_REC_DBD_2	coord: 43..118 score: 15.267
IPR013088	Zinc finger, NHR/GATA-type	GENE3D	G3DSA:3.30.50.10		coord: 128..221 e-value: 9.6E-24 score: 85.4
IPR013088	Zinc finger, NHR/GATA-type	GENE3D	G3DSA:3.30.50.10		coord: 36..127 e-value: 1.4E-19 score: 72.0
None	No IPR available	PANTHER	PTHR24082	NUCLEAR HORMONE RECEPTOR	coord: 125..455
None	No IPR available	PANTHER	PTHR24082:SF473	NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-2	coord: 33..113
None	No IPR available	PANTHER	PTHR24082:SF473	NUCLEAR HORMONE RECEPTOR FAMILY MEMBER NHR-2	coord: 125..455
None	No IPR available	PANTHER	PTHR24082	NUCLEAR HORMONE RECEPTOR	coord: 33..113
None	No IPR available	CDD	cd07179	2DBD_NR_DBD2	coord: 130..204 e-value: 1.1064E-29 score: 109.514
None	No IPR available	SUPERFAMILY	SSF57716	Glucocorticoid receptor-like (DNA-binding domain)	coord: 127..214
None	No IPR available	SUPERFAMILY	SSF57716	Glucocorticoid receptor-like (DNA-binding domain)	coord: 43..123
IPR000536	Nuclear hormone receptor, ligand-binding domain	PROSITE	PS51843	NR_LBD	coord: 289..563 score: 12.455
IPR035500	Nuclear hormone receptor-like domain superfamily	SUPERFAMILY	SSF48508	Nuclear receptor ligand-binding domain	coord: 264..465

Main menu

Nuclear receptor 2DBD gamma

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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