Expressed conserved protein

Overview
NameExpressed conserved protein
Smed IDSMED30001663
Length (bp)4638
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Expressed conserved protein (SMED30001663) t-SNE clustered cells

Violin plots show distribution of expression levels for Expressed conserved protein (SMED30001663) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Expressed conserved protein (SMED30001663) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Expressed conserved protein (SMED30001663) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30001663

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30001663SMESG000057766.1 dd_Smed_v4_4288_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30001663SMESG000057766.1 dd_Smed_v4_4288_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001663SMESG000057766.1 dd_Smed_v4_4288_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30001663SMESG000057766.1 dd_Smed_v4_4288_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001663SMESG000057766.1 dd_Smed_v4_4288_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001663SMESG000057766.1 dd_Smed_v4_6533_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Expressed conserved protein vs. TrEMBL
Match: A0A267GJT7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009462g1 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.469e-18
Identity = 56/158 (35.44%), Postives = 88/158 (55.70%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLS---NLVVNEPIEFS---VDNWENDDEESWIRLFDLIKVKWEP 588
            +KL L+T   YSK  +    D   E FA +L+ +S++EF++ CK     G AFI  F  FE  FL  SEY +I+ S  S +    F+PRLLVFLT + +W NRFI   +G V +     + + + P+ F+    ++W   + +SW  L+ ++++ W P
Sbjct:  203 FKLILMTSRSYSKESND---DGRGEAFAQFLQQKSESEFSMSCKIPSSSGSAFITDFNKFENEFLRVSEYCLIVVSEESVRRFRIFLPRLLVFLTRRSVWSNRFIIACVGNVDLRESEVDFLTHPPVYFTSTEAESWST-EVQSWQILYRILRITWAP 356          

HSP 2 Score: 94.7449 bits (234), Expect = 1.575e-15
Identity = 56/159 (35.22%), Postives = 85/159 (53.46%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSN---FQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNL----VVNEPIEFSVDNWEN--DDEESWIRLFDLIKVKW 582
            YK +++ P +Y +A  S     QD    +F  +LK  ++  F + C      G AFI +F  FE  FL  SEY III S  + K LN+F+ RLLVF+T + +W++RFIF+ LG+ + L  L     V++ I F     E    + E W  L+ ++ + W
Sbjct:   13 YKFSILAPEVYCQAIKSAEPVKQDDAAYRFGLFLKQWAEEVFGMSCFVPSSSGAAFIENFNTFESDFLAKSEYCIIIISEVAAKPLNRFLARLLVFVTMRAMWRSRFIFIALGEFEGLKKLHLDVSVHDLIIFKSRTEEGWMVETECWKALYFILNISW 171          
BLAST of Expressed conserved protein vs. TrEMBL
Match: A0A267EUB7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018063g1 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.795e-18
Identity = 58/158 (36.71%), Postives = 90/158 (56.96%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLS---NLVVNEPIEFS---VDNWENDDEESWIRLFDLIKVKWEP 588
            +KL L+T   YSK   SN  D   E FA +L+ +S++EF++ CK     G AFI  F  FE  FL  SEY +I+ S  S +    F+PRLLVFLT + +W NRFI   +G V +     + + + P+ F+    ++W + + +SW  L+ ++++ W P
Sbjct:  204 FKLILMTSRSYSK--ESN-DDGRGEAFAQFLQQKSESEFSMSCKIPSSSGSAFITDFNKFENEFLRVSEYCLIVVSEESVRRFRIFLPRLLVFLTRRSVWSNRFIIACVGNVDLRESEVDFLTHPPVYFTSTEAESW-STEVQSWQILYRILRITWAP 357          

HSP 2 Score: 97.0561 bits (240), Expect = 2.831e-16
Identity = 56/164 (34.15%), Postives = 86/164 (52.44%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSN---FQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNL----VVNEPIEFSVDNWEN--DDEESWIRLFDLIKVKWEPHVD 597
            YK +++ P +Y +A  S     QD    +F  +LK  ++  F + C      G AFI +F  FE  FL  SEY +II S  + K LN+F+ RLLVF+T + +W++RFIF+ LG+ + L  L     V++ I F     E    + E W  L+ ++ + W    D
Sbjct:   14 YKFSILAPEVYCQAIKSAEPVKQDDAAYRFGLFLKQWAEEVFGMSCFVPSSSGAAFIENFNTFESDFLAKSEYCVIIISEVAAKPLNRFLARLLVFVTMRAMWRSRFIFIALGEFEGLKKLHLDVSVHDLIIFKSRTEEGWMVETECWKALYFILNISWASLGD 177          
BLAST of Expressed conserved protein vs. TrEMBL
Match: A0A267FUN4 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030938g1 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 2.364e-18
Identity = 58/158 (36.71%), Postives = 90/158 (56.96%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLS---NLVVNEPIEFS---VDNWENDDEESWIRLFDLIKVKWEP 588
            +KL L+T   YSK   SN  D   E FA +L+ +S++EF++ CK     G AFI  F  FE  FL  SEY +I+ S  S +    F+PRLLVFLT + +W NRFI   +G V +     + + + P+ F+    ++W + + +SW  L+ ++++ W P
Sbjct:  203 FKLILMTSRSYSK--ESN-DDGRGEAFAQFLQQKSESEFSMSCKIPSSSGSAFITDFNKFENEFLRVSEYCLIVVSEESVRRFRIFLPRLLVFLTRRSVWSNRFIIACVGNVDLRESEVDFLTHPPVYFTSTEAESW-STEVQSWQILYRILRITWAP 356          

HSP 2 Score: 97.0561 bits (240), Expect = 2.745e-16
Identity = 57/164 (34.76%), Postives = 86/164 (52.44%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSN---FQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNL----VVNEPIEFSVDNWEN--DDEESWIRLFDLIKVKWEPHVD 597
            YK +++ P +Y +A  S     QD    +F  +LK  ++  F + C      G AFI +F  FE  FL  SEY III S  + K LN+F+ RLLVF+T + +W++RFIF+ LG+ + L  L     V++ I F     E    + E W  L+ ++ + W    D
Sbjct:   13 YKFSILAPEVYCQAIKSAEPVKQDDAAYRFGLFLKQWAEEVFGMSCFVPSSSGAAFIENFNTFESDFLAKSEYCIIIISEVAAKPLNRFLARLLVFVTMRAMWRSRFIFIALGEFEGLKKLHLDVSVHDLIIFKSRTEEGWMVETECWKALYFILNISWASLGD 176          
BLAST of Expressed conserved protein vs. TrEMBL
Match: A0A1I8F2N9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 8.246e-17
Identity = 60/162 (37.04%), Postives = 92/162 (56.79%), Query Frame = 1
Query:  133 YKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFI-------FVILGKVKVLSNLVVNEPIEFS---VDNWENDDEESWIRLFDLIKVKWEP 588
            +KL L+T   YSK   SN  D   E FA +L+ +S++EF++ CK     G AFI  F  FE  FL  SEY +I+ S  S +    F+PRLLVFLT + +W NRFI       FV L + +V  + + + P+ F+    ++W + + +SW  L+ ++++ W P
Sbjct:  155 FKLILMTSRSYSK--ESN-DDGRGEAFAQFLQQKSESEFSMSCKIPSSSGSAFITDFNKFENEFLRVSEYCLIVVSEESVRRFRIFLPRLLVFLTRRSVWSNRFIIACVVIAFVDLRESEV--DFLTHPPVYFTSTEAESW-STEVQSWQILYRILRITWAP 310          

HSP 2 Score: 82.0333 bits (201), Expect = 1.199e-11
Identity = 46/123 (37.40%), Postives = 66/123 (53.66%), Query Frame = 1
Query:  247 FNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNL----VVNEPIEFSVDNWEN--DDEESWIRLFDLIKVKWEPHVD 597
            F + C      G AFI +F  FE  FL  SEY III S  + K LN+F+ RLLVF+T + +W++RFIF+ LG+ + L  L     V++ I F     E    + E W  L+ ++ + W    D
Sbjct:    6 FGMSCFVPSSSGAAFIENFNTFESDFLAKSEYCIIIISEVAAKPLNRFLARLLVFVTMRAMWRSRFIFIALGEFEGLKKLHLDVSVHDLIIFKSRTEEGWMVETECWKALYFILNISWASLGD 128          
BLAST of Expressed conserved protein vs. TrEMBL
Match: A0A183N575 (Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS23450 PE=4 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 3.894e-16
Identity = 59/161 (36.65%), Postives = 89/161 (55.28%), Query Frame = 1
Query:  127 MDYKLNLITPS--LYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIH-SFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSN----LVVNEPIEF---SVDNWENDDEESWIRLFDLIKVK 579
            M +K  L+T    L +   +++ +D+    FA YL   ++ ++ L   +    G AF+H SF  FEERFL HSEYA++I S  +   LN   PR LVFLT+K  W  R + + L +   L N    L+ + PI F   S + W + D+ESW+++ +LIK K
Sbjct:    1 MKFKFTLLTSWTLLPTSIPNTDCEDNEAILFAQYLTEYTENKYGLNVFWPRQRGEAFLHNSFNSFEERFLTHSEYALLIVSGQNASCLNCIYPRFLVFLTAKKSWTERILIIFLKQPTYLLNFDLSLLKHPPILFNDDSTNQWTH-DQESWMKIAELIKRK 160          
BLAST of Expressed conserved protein vs. Planmine SMEST
Match: SMESG000057766.1 (SMESG000057766.1)

HSP 1 Score: 2635.14 bits (6829), Expect = 0.000e+0
Identity = 1409/1414 (99.65%), Postives = 1412/1414 (99.86%), Query Frame = 1
Query:  127 MDYKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNLVVNEPIEFSVDNWENDDEESWIRLFDLIKVKWEPHVDKLVPDSSPNNKLHVTENDNNDPMVNYSQISEFENNENRSLNFSQKVETTNLPDPLSVIQHKPLEFENHSETVPXXXXXXXQVKNLANRSIQGSNVVLENLTFSKAESDNITNPKVFTESYANTEESIFTLTRESXXXXXXXXXXXXXXXXXXXXXXXXXDSDTYSEQSFECAPVNLTELIEENDDEGSDDIQINKIYHQHQEVAEDPVSDFLYTKPVRTEGNHIDSSLAEIKSDGTEVSIESIRSNPDDNSKTLISNDVNSVKDIHTDKNILNFKSNSDDTKDKNINKRFDLNVDDVESENIEISPKNLTNILEEISRKEVNSVNKINLDKISQLSKVNEKGLEGAEDSSNNLSTITGSCLLTSMVSDLKGKETPGEISEENINSAKKKNESQLIQKGXXXXXXXXXXXXXVTINDKCLRTSNDSSLKEKENPEIAVKPIIRSIQYHDMLLLYTKDXXXXXXXXXXXXXXHSGAHFEDIPHSVEEYDLLHKNENGTETKKNISNEILGNTIKDTSGDSCLIEKVFIETSSEANTSLVNAKNISQVKGKKNEISNEVPFDITKAKGIPTHNDSYLKEKEYSEAKFEPNTHLDKDADLLFIXXXXXXXXXXXXXXXISANIIKEKCLSTQDDSCLKEKELLVISSEEITNLPKDNNTSQINEKDTKQKGNTPNEILVNSIKDKCLSNQCDSCLKKEESLAICSEETTNLSKDNNMLQVNDKDTEGEENKSNEMPSEAIKVKCSQIYTDSGLDESETRDVNVVFCPPDINKNVGKMDPTADIKSVNNSFDETPKCDSETNEIFLNRNGQIFFESQAFEFTASPAKYDTNNEEYSNPNILTPSFEMEKSFDNNGKAISIRDANLQKETDHEIEDIITNFEGTEVGYSISTEYDEASEITKKKMNYLXXXXXXXXXXXXDIFYRPIVIENDMSKNVDEFMGSCSLNMGEIYQFTKNDMFVSSENGKILEKDSIININFEPIAIDSSKTEYVDIDIGSRITFSSVDIYTNVSGNKNQNPVPKRRXXXXXXXXXXXXVGLPNANPVKTQDIELTAGSSDAFNFRNTGNKRKAFDEIVVNEDCEIISTIGNEEKQFVEHFGKTNVRTNQEKTTNWTNSDQNFEINDKASNTLNLSQHRLNLKHSSTKRERQPHFKGSSHISFSFLSKFKTIHTFIKRIVFRENRVSSCCQQEEHSNHKEDSITRCLHSPWCVLLVFVGGTLASPYWVELTKNISQRAVEPGFLVDTIASTALHEEKVIGKYNHYF 4368
            MDYKLNLITPSLYSKAGSSNFQD+IVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNLVVNEPIEFSVDNWENDDEESWIRLFDLIKVKWEPHVDKLVPDSSPNNKLHVTENDNNDPMVNYSQISEFENNENRSLNFSQKVETTNLPDPLSVIQHKPLEFENHSETVPKTTTTKTQVKNLANRSIQGSNVVLENLTFSKAESDNITNPKVFTESYANTEESIFTLTRESNENQLKQEMEQKEENNSESSQISNNDSDTYSEQSFECAPVNLTELIEENDDEGSDDIQINKIYHQHQEVAEDPVSDFLYTKPVRTEGNHIDSSLAEIKSDGTEVSIESIRSNPDDNSKTLISNDVNSVKDIHTDKNILNFKSNSDDTKDKNINKRFDLNVDDVESENIEISPKNLTNILEEISRKEVNSVNKINLDKISQLSKVNEKGLEGAEDSSNNLSTITGSCLLTSMVSDLKGKETPGEISEENINSAKKKNESQLIQKGTEEKENTSSENSSVTINDKCLRTSNDSSLKEKENPEIAVKPIIRSIQYHDMLLLYTKDTEEKESTSKEIAAEHSGAHFEDIPHSVEEYDLLHKNENGTETKKNISNEILGNTIKDTSGDSCLIEK FIETSSEANTSLVNAKNISQVKGKKNEISNEVPFDITKAKGIPTHNDSYLKEKEYSEAKFEPNTHLDKDADLLFINKK+ESKEKENAANEISANIIKEKCLSTQDDSCLKEKELLVISSEEITNLPKDNNTSQINEKDTKQKGNTPNEILVNSIKDKCLSNQCDSCLKKEESLAICSEETTNLSKDNNMLQVNDKDTEGEENKSNEMPSEAIKVKCSQIYTDSGLDESETRDVNVVFCPPDINKNVGKMDPTADIKSVNNSFDETPKCDSETNEIFLNRNGQIFFESQAFEFTASPAKYDTNNEEYSNPNILTPSFEMEKSFDNNGKAISIRDANL KETDHEIEDIITNFEGTEVGYSISTEYDEASEITKKKMNYLSNNEKEISSSENDIFYRPIVIENDMSKNVDEFMGSCSLNMGEIYQFTKNDMFVSSENGKILEKDSIININFEPIAIDSSKTEYVDIDIGSRITFSSVDIYTNVSGNKNQNPVPKRR+IGNIEEEIAGEVGLPNANPVKTQDIELTAGSSDAFNFRNTGNKRKAFDEIVVNEDCEIISTIGNEEKQFVEHFGKTNVRTNQEKTTNWTNSDQNFEINDKASNTLNLSQHRLNLKHSSTKRERQPHFKGSSHISFSFLSKFKTIHTFIKRIVFRENRVSSCCQQEEHSNHKEDSITRCLHSPWCVLLVFVGGTLASPYWVELTKNISQRAVEPGFLVDTIASTALHEEKVIGKYNHYF
Sbjct:    1 MDYKLNLITPSLYSKAGSSNFQDAIVEKFAHYLKYRSDTEFNLKCKFDPVPGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKPIWQNRFIFVILGKVKVLSNLVVNEPIEFSVDNWENDDEESWIRLFDLIKVKWEPHVDKLVPDSSPNNKLHVTENDNNDPMVNYSQISEFENNENRSLNFSQKVETTNLPDPLSVIQHKPLEFENHSETVPKTTTTKTQVKNLANRSIQGSNVVLENLTFSKAESDNITNPKVFTESYANTEESIFTLTRESNENQLKQEMEQKEENNSESSQISNNDSDTYSEQSFECAPVNLTELIEENDDEGSDDIQINKIYHQHQEVAEDPVSDFLYTKPVRTEGNHIDSSLAEIKSDGTEVSIESIRSNPDDNSKTLISNDVNSVKDIHTDKNILNFKSNSDDTKDKNINKRFDLNVDDVESENIEISPKNLTNILEEISRKEVNSVNKINLDKISQLSKVNEKGLEGAEDSSNNLSTITGSCLLTSMVSDLKGKETPGEISEENINSAKKKNESQLIQKGTEEKENTSSENSSVTINDKCLRTSNDSSLKEKENPEIAVKPIIRSIQYHDMLLLYTKDTEEKESTSKEIAAEHSGAHFEDIPHSVEEYDLLHKNENGTETKKNISNEILGNTIKDTSGDSCLIEKGFIETSSEANTSLVNAKNISQVKGKKNEISNEVPFDITKAKGIPTHNDSYLKEKEYSEAKFEPNTHLDKDADLLFINKKKESKEKENAANEISANIIKEKCLSTQDDSCLKEKELLVISSEEITNLPKDNNTSQINEKDTKQKGNTPNEILVNSIKDKCLSNQCDSCLKKEESLAICSEETTNLSKDNNMLQVNDKDTEGEENKSNEMPSEAIKVKCSQIYTDSGLDESETRDVNVVFCPPDINKNVGKMDPTADIKSVNNSFDETPKCDSETNEIFLNRNGQIFFESQAFEFTASPAKYDTNNEEYSNPNILTPSFEMEKSFDNNGKAISIRDANLHKETDHEIEDIITNFEGTEVGYSISTEYDEASEITKKKMNYLSNNEKEISSSENDIFYRPIVIENDMSKNVDEFMGSCSLNMGEIYQFTKNDMFVSSENGKILEKDSIININFEPIAIDSSKTEYVDIDIGSRITFSSVDIYTNVSGNKNQNPVPKRRSIGNIEEEIAGEVGLPNANPVKTQDIELTAGSSDAFNFRNTGNKRKAFDEIVVNEDCEIISTIGNEEKQFVEHFGKTNVRTNQEKTTNWTNSDQNFEINDKASNTLNLSQHRLNLKHSSTKRERQPHFKGSSHISFSFLSKFKTIHTFIKRIVFRENRVSSCCQQEEHSNHKEDSITRCLHSPWCVLLVFVGGTLASPYWVELTKNISQRAVEPGFLVDTIASTALHEEKVIGKYNHYF 1414          
The following BLAST results are available for this feature:
BLAST of Expressed conserved protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GJT71.469e-1835.44Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267EUB71.795e-1836.71Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267FUN42.364e-1836.71Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8F2N98.246e-1737.04Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A183N5753.894e-1636.65Uncharacterized protein OS=Schistosoma margrebowie... [more]
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BLAST of Expressed conserved protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Expressed conserved protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000057766.10.000e+099.65SMESG000057766.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001663 ID=SMED30001663|Name=Expressed conserved protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4638bp
CGATGCAACACACACATACAAATACACACTAATACCTTGCAATCTGATTG
GCTAATTGACATATGTCTATTGATTGATTTTACATTTTAGTTTCACAGTT
AATTTCGCTTTTCGACAGAAGTTTTCATGGATTATAAACTAAATCTCATT
ACTCCAAGTCTTTACTCGAAAGCCGGCTCATCTAACTTCCAGGATTCTAT
CGTTGAAAAGTTCGCTCATTATCTGAAATACAGATCCGATACTGAATTTA
ATCTTAAATGCAAATTTGATCCTGTTCCAGGACTAGCATTCATTCACAGT
TTTGAAGATTTTGAGGAGAGATTTCTCATTCATTCAGAATATGCCATAAT
CATTGCATCGCCTGCTTCACAGAAAGCTTTAAATCAATTTATACCCAGAT
TATTGGTTTTCTTGACATCAAAACCTATTTGGCAGAATAGATTTATATTT
GTAATTTTGGGAAAAGTTAAAGTTTTGAGCAATTTGGTTGTAAACGAACC
GATAGAGTTTTCAGTCGATAATTGGGAAAATGACGATGAAGAAAGTTGGA
TCAGATTATTTGATTTGATTAAAGTCAAATGGGAACCCCATGTAGATAAA
TTGGTCCCAGATTCTAGTCCCAATAATAAGTTGCATGTCACCGAAAATGA
CAATAATGATCCTATGGTCAATTATTCACAGATTTCAGAATTTGAAAATA
ATGAGAATAGAAGTCTCAATTTTAGTCAGAAAGTTGAAACCACCAATCTA
CCTGATCCACTTTCAGTAATTCAACATAAACCATTAGAATTTGAGAACCA
TTCGGAAACAGTTCCTAAAACGACCACTACAAAAACACAGGTAAAGAATT
TAGCTAACCGTAGTATTCAAGGATCGAATGTCGTTCTGGAAAACTTAACA
TTTTCAAAAGCAGAAAGTGACAATATTACTAACCCAAAGGTATTCACAGA
ATCATATGCCAATACAGAAGAGTCGATATTTACTCTCACTCGTGAATCGA
ATGAAAATCAACTCAAACAAGAGATGGAACAAAAAGAAGAAAATAATAGT
GAATCTAGTCAGATCTCAAACAATGATTCTGACACTTACAGTGAACAGAG
CTTTGAATGTGCACCAGTTAACTTAACCGAACTAATAGAAGAAAATGATG
ATGAAGGAAGTGATGACATTCAAATAAATAAAATATACCATCAACACCAA
GAGGTAGCAGAAGATCCGGTGAGTGATTTTTTATATACTAAACCTGTCAG
GACCGAAGGAAATCATATTGATAGTTCTTTGGCCGAGATAAAATCTGATG
GAACTGAAGTAAGTATAGAAAGTATAAGATCCAATCCTGATGATAATTCG
AAAACTTTGATCAGTAATGACGTGAATAGCGTCAAAGATATTCATACTGA
TAAAAACATTCTTAATTTCAAAAGTAATTCAGACGATACGAAAGATAAAA
ACATTAACAAAAGGTTTGACCTAAATGTAGACGATGTAGAAAGTGAAAAT
ATTGAAATTTCACCAAAGAATCTGACGAACATACTTGAAGAAATTTCAAG
AAAGGAAGTAAATTCTGTGAATAAAATAAATTTAGATAAAATCAGTCAAC
TTTCAAAAGTAAATGAAAAAGGTTTAGAAGGAGCAGAGGACAGCTCAAAT
AACTTGTCAACAATCACAGGCAGTTGCTTATTGACGTCAATGGTTTCTGA
CTTGAAGGGAAAAGAAACTCCAGGTGAAATTTCTGAAGAAAATATAAATT
CAGCTAAAAAGAAAAATGAATCACAGCTAATTCAAAAAGGCACAGAAGAA
AAAGAAAACACGTCAAGTGAAAATTCAAGTGTTACAATAAATGATAAATG
TTTAAGGACATCAAATGATTCTTCTTTAAAGGAAAAAGAAAACCCAGAAA
TAGCAGTTAAGCCTATTATACGTTCGATTCAATACCACGATATGTTGCTT
TTATATACAAAAGACACAGAAGAAAAGGAGAGTACGTCAAAGGAAATAGC
TGCCGAGCATTCAGGAGCACATTTTGAGGATATTCCACATTCAGTTGAGG
AATATGATTTGTTACATAAAAATGAAAACGGCACAGAAACAAAGAAAAAT
ATATCAAACGAAATATTAGGAAATACAATAAAAGACACATCCGGTGATTC
TTGTTTGATAGAAAAGGTATTTATTGAAACGAGTTCTGAAGCTAATACAA
GTTTAGTTAATGCTAAGAATATATCACAAGTAAAAGGAAAGAAGAATGAA
ATTTCAAACGAAGTTCCATTTGACATAACAAAAGCAAAAGGTATACCGAC
ACACAACGATTCTTATTTGAAAGAAAAAGAATATTCAGAAGCAAAATTTG
AACCTAATACACATTTAGATAAGGACGCCGATTTATTATTTATAAATAAA
AAAGAAGAATCAAAAGAGAAAGAAAATGCGGCAAATGAAATATCAGCCAA
TATAATAAAAGAGAAATGTTTATCGACTCAAGATGATTCATGTTTGAAGG
AGAAAGAACTTTTAGTTATAAGTTCTGAGGAAATCACAAATTTGCCTAAA
GACAACAATACATCACAAATAAATGAAAAGGACACAAAACAAAAGGGGAA
CACCCCAAATGAAATATTAGTCAATTCAATAAAAGACAAATGTTTATCGA
ATCAATGTGATTCTTGTTTGAAGAAAGAAGAATCTTTAGCTATATGTTCT
GAGGAAACTACAAATTTATCTAAAGACAACAATATGTTACAAGTAAATGA
TAAAGACACTGAAGGAGAGGAAAATAAGTCAAACGAAATGCCATCTGAAG
CAATAAAAGTCAAATGTTCACAGATATACACTGATTCTGGCTTAGATGAA
AGCGAAACTCGAGACGTAAATGTAGTTTTTTGTCCGCCTGATATCAATAA
AAATGTTGGAAAAATGGATCCAACCGCCGATATAAAGAGTGTAAATAATT
CATTTGATGAAACACCTAAATGTGACAGTGAGACTAATGAAATATTTCTA
AATAGAAATGGACAAATTTTCTTTGAATCTCAGGCATTTGAATTTACGGC
GTCACCTGCTAAATACGATACTAATAATGAAGAATATAGTAATCCTAATA
TTTTAACCCCTAGCTTTGAAATGGAGAAGTCATTTGACAATAATGGAAAA
GCAATTTCAATTAGAGATGCCAATTTACAAAAGGAGACCGACCACGAAAT
TGAGGATATTATTACTAATTTTGAAGGAACAGAAGTAGGATATTCTATAT
CCACAGAATATGATGAAGCGTCTGAAATCACAAAGAAAAAAATGAATTAT
CTCTCGAATAATGAAAAGGAAATATCCTCATCGGAAAACGATATCTTTTA
TCGGCCTATAGTTATTGAAAATGACATGTCCAAAAATGTCGATGAATTTA
TGGGAAGTTGCAGTTTAAATATGGGTGAGATTTACCAATTCACAAAGAAC
GACATGTTTGTGAGTAGTGAAAATGGTAAAATACTCGAAAAGGATTCTAT
CATAAATATTAATTTTGAACCCATAGCCATAGACTCTAGCAAAACAGAAT
ACGTAGATATTGATATCGGATCCAGAATTACCTTTTCAAGTGTTGATATA
TATACCAACGTCTCAGGAAATAAAAATCAGAATCCCGTACCGAAAAGGCG
AGCAATCGGAAATATAGAGGAAGAGATTGCAGGCGAGGTAGGTTTACCTA
ATGCAAATCCAGTTAAGACTCAAGATATAGAATTAACTGCCGGAAGTTCA
GACGCATTTAATTTTAGAAATACAGGAAACAAAAGAAAGGCATTCGATGA
AATAGTTGTTAATGAAGATTGTGAGATAATATCAACTATAGGCAATGAGG
AAAAACAGTTTGTCGAGCATTTTGGAAAAACAAATGTAAGGACAAATCAA
GAAAAAACGACTAATTGGACGAATTCAGATCAAAACTTTGAGATCAATGA
TAAAGCTTCTAATACACTAAATTTGAGTCAGCATAGACTCAATTTAAAAC
ATTCAAGTACGAAAAGAGAACGTCAACCCCACTTTAAAGGTTCAAGCCAT
ATTTCGTTTAGTTTTTTATCGAAATTCAAAACCATTCATACATTTATCAA
AAGAATTGTGTTCCGCGAAAATCGGGTTTCATCGTGTTGTCAGCAAGAAG
AGCATTCAAATCATAAAGAAGATTCCATAACCAGATGTCTCCATTCTCCT
TGGTGTGTTTTGCTAGTGTTTGTCGGTGGGACATTGGCATCACCATACTG
GGTTGAATTAACAAAAAATATTAGCCAACGAGCAGTTGAACCTGGTTTTC
TCGTTGACACGATTGCTTCAACAGCTCTGCATGAAGAGAAAGTTATAGGA
AAATATAATCACTATTTTTAGATATTTATTTAGACTTGAAATTTTGTGTT
TTGTTTAACTCGATAAACGCTCAAATCTATAATATCATTCATGCGTTGTT
TTAATATTCGGATCAAATTGTATTGCTTTATTTACTGACATGATTATCTC
TCAATTGCTTGCTGAACCATGACGTTGCTTTAGCTCAGATTGCCGCGTAT
GGGTTATTGTCGACTCTTGTATTTTTATACACTTCATTGTTCTGCAGTTT
TTCCTCATAAAATATTCGATTTAAACAAATAAAATGAG
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protein sequence of SMED30001663-orf-1

>SMED30001663-orf-1 ID=SMED30001663-orf-1|Name=SMED30001663-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1415bp
MDYKLNLITPSLYSKAGSSNFQDSIVEKFAHYLKYRSDTEFNLKCKFDPV
PGLAFIHSFEDFEERFLIHSEYAIIIASPASQKALNQFIPRLLVFLTSKP
IWQNRFIFVILGKVKVLSNLVVNEPIEFSVDNWENDDEESWIRLFDLIKV
KWEPHVDKLVPDSSPNNKLHVTENDNNDPMVNYSQISEFENNENRSLNFS
QKVETTNLPDPLSVIQHKPLEFENHSETVPKTTTTKTQVKNLANRSIQGS
NVVLENLTFSKAESDNITNPKVFTESYANTEESIFTLTRESNENQLKQEM
EQKEENNSESSQISNNDSDTYSEQSFECAPVNLTELIEENDDEGSDDIQI
NKIYHQHQEVAEDPVSDFLYTKPVRTEGNHIDSSLAEIKSDGTEVSIESI
RSNPDDNSKTLISNDVNSVKDIHTDKNILNFKSNSDDTKDKNINKRFDLN
VDDVESENIEISPKNLTNILEEISRKEVNSVNKINLDKISQLSKVNEKGL
EGAEDSSNNLSTITGSCLLTSMVSDLKGKETPGEISEENINSAKKKNESQ
LIQKGTEEKENTSSENSSVTINDKCLRTSNDSSLKEKENPEIAVKPIIRS
IQYHDMLLLYTKDTEEKESTSKEIAAEHSGAHFEDIPHSVEEYDLLHKNE
NGTETKKNISNEILGNTIKDTSGDSCLIEKVFIETSSEANTSLVNAKNIS
QVKGKKNEISNEVPFDITKAKGIPTHNDSYLKEKEYSEAKFEPNTHLDKD
ADLLFINKKEESKEKENAANEISANIIKEKCLSTQDDSCLKEKELLVISS
EEITNLPKDNNTSQINEKDTKQKGNTPNEILVNSIKDKCLSNQCDSCLKK
EESLAICSEETTNLSKDNNMLQVNDKDTEGEENKSNEMPSEAIKVKCSQI
YTDSGLDESETRDVNVVFCPPDINKNVGKMDPTADIKSVNNSFDETPKCD
SETNEIFLNRNGQIFFESQAFEFTASPAKYDTNNEEYSNPNILTPSFEME
KSFDNNGKAISIRDANLQKETDHEIEDIITNFEGTEVGYSISTEYDEASE
ITKKKMNYLSNNEKEISSSENDIFYRPIVIENDMSKNVDEFMGSCSLNMG
EIYQFTKNDMFVSSENGKILEKDSIININFEPIAIDSSKTEYVDIDIGSR
ITFSSVDIYTNVSGNKNQNPVPKRRAIGNIEEEIAGEVGLPNANPVKTQD
IELTAGSSDAFNFRNTGNKRKAFDEIVVNEDCEIISTIGNEEKQFVEHFG
KTNVRTNQEKTTNWTNSDQNFEINDKASNTLNLSQHRLNLKHSSTKRERQ
PHFKGSSHISFSFLSKFKTIHTFIKRIVFRENRVSSCCQQEEHSNHKEDS
ITRCLHSPWCVLLVFVGGTLASPYWVELTKNISQRAVEPGFLVDTIASTA
LHEEKVIGKYNHYF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002032epidermal cell
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 289..313
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 528..574
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 297..325
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 808..827
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 530..561
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 307..325