SMED30001652

Overview
NameSMED30001652
Smed IDSMED30001652
Length (bp)746
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30001652 (SMED30001652) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30001652 (SMED30001652) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30001652 (SMED30001652) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30001652 (SMED30001652) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001652

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30001652h1SMcG0018986 Contig36770uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001652h1SMcG0018986 Contig36770newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001652h1SMcG0018986 Contig41321newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001652h1SMcG0018986 Contig41321uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001652h1SMcG0018987 Contig36770uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001652h1SMcG0018987 Contig36770newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30001652h1SMcG0018986 dd_Smed_v4_1029_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001652h1SMcG0018986 dd_Smed_v4_1029_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30001652 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.000230:175540..176337 -3237
Homology
[Close]
BLAST of SMED30001652 vs. TrEMBL
Match: A0A1W7RA66 (Methyltransferase-like protein OS=Hadrurus spadix OX=141984 PE=4 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 2.636e-12
Identity = 44/135 (32.59%), Postives = 66/135 (48.89%), Query Frame = 3 
Query:   75 TKWLYNESGRYQEDTVYAGLN----CRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDA-GNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVH 464
             +WL+  SG+     V  G +      VARA  +G+ + G LL    CVY+S        + Y+V     N + ++LEWK+  G  VP GA+ GG+ A G  L+IGR   +G + VG  +     + + Y  R H
Sbjct:   13 AEWLFGSSGQVPPCAVQGGYDGGDTIYVARAHHNGDNIPGKLLPSHGCVYVSWGGEEHSHHSYEVLC---NPQGSQLEWKYCGGGDVPSGAVQGGTTADGEPLYIGRHEHEGTMTVGKVQPSHQVLYIAYGGREH 144
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BLAST of SMED30001652 vs. TrEMBL
Match: A0A2I9LP56 (Methyltransferase-like protein OS=Centruroides hentzi OX=88313 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.889e-12
Identity = 45/146 (30.82%), Postives = 69/146 (47.26%), Query Frame = 3 
Query:   75 TKWLYNESGRYQEDTVYAGLNCR----VARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDA-GNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDIL-CK 494
             +W+   SG      V AG +      VARA  +G+ + G L+    C Y+         + YQV     N +  +LEW++ SG  +P GA+ GG  A G  L+IGR   +G + VG  +   G + + +  R H  P  ++L CK
Sbjct:   13 AEWVPASSGHVPPCAVQAGYDVSDTLYVARAHHNGDNIPGKLVPSHGCCYVPWGGEEHSHHSYQVLC---NPEGVQLEWRFTSGGDIPPGAVQGGMTADGEPLYIGRHDHEGTMTVGKVQPSHGVLYIAFGGREHSYPDYEVLVCK 155
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BLAST of SMED30001652 vs. TrEMBL
Match: Q686R4 (CG10527-like methyltransferase (Fragment) OS=Mesobuthus gibbosus OX=123226 GN=mt PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 6.518e-10
Identity = 37/118 (31.36%), Postives = 59/118 (50.00%), Query Frame = 3 
Query:  114 DTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGG-SDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVH 464
            D++Y      VARA  +G+ + G L+    C Y+         +EYQV     N +  +LEW++ASG  +P GAI GG +  G  L+IGR   +G + +G  +   G + + +    H
Sbjct:    8 DSIY------VARAHHNGDNIPGKLVPSHGCCYVPWGGEEHRHHEYQVLC---NPEGMQLEWRFASGGDIPPGAIQGGMTSDGEPLYIGRHEHEGTMTIGKXQPSHGVVYISFGGGEH 116
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BLAST of SMED30001652 vs. TrEMBL
Match: Q686V2 (CG10527-like methyltransferase (Fragment) OS=Mesobuthus gibbosus OX=123226 GN=mettrans PE=4 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 7.449e-10
Identity = 37/118 (31.36%), Postives = 59/118 (50.00%), Query Frame = 3 
Query:  114 DTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGG-SDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVH 464
            D++Y      VARA  +G+ + G L+    C Y+         +EYQV     N +  +LEW++ASG  +P GAI GG +  G  L+IGR   +G + +G  +   G + + +    H
Sbjct:    8 DSIY------VARAHHNGHNIPGKLVPSHGCCYVPWGGEEHRHHEYQVLC---NPEGMQLEWRFASGGDIPPGAIQGGMTSDGEPLYIGRHEHEGTMTIGKIQPSHGVVYISFGGGEH 116
[Close]
BLAST of SMED30001652 vs. TrEMBL
Match: Q686U9 (CG10527-like methyltransferase (Fragment) OS=Mesobuthus gibbosus OX=123226 GN=mt PE=4 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 7.683e-10
Identity = 37/118 (31.36%), Postives = 59/118 (50.00%), Query Frame = 3 
Query:  114 DTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGG-SDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVH 464
            D++Y      VARA  +G+ + G L+    C Y+         +EYQV     N +  +LEW++ASG  +P GAI GG +  G  L+IGR   +G + +G  +   G + + +    H
Sbjct:    8 DSIY------VARAHHNGDNIPGKLVPSHGCCYVPWGGEEHRHHEYQVLC---NPEGMQLEWRFASGGDIPPGAIQGGMTSDGEPLYIGRHEHEGTMTIGKIQPSHGVVYISFGGGEH 116
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BLAST of SMED30001652 vs. Planmine SMEST
Match: SMESG000027142.1 (SMESG000027142.1)

HSP 1 Score: 323.553 bits (828), Expect = 6.427e-114
Identity = 158/159 (99.37%), Postives = 159/159 (100.00%), Query Frame = 3 
Query:   33 MSNDKRLGDIVDGQTKWLYNESGRYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKVSSES 509
            MSNDKRLGDIVDGQTKWLYNESG+YQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKVSSES
Sbjct:    1 MSNDKRLGDIVDGQTKWLYNESGKYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKVSSES 159
[Close]
BLAST of SMED30001652 vs. Planmine SMEST
Match: SMESG000027140.1 (SMESG000027140.1)

HSP 1 Score: 141.739 bits (356), Expect = 1.992e-42
Identity = 68/147 (46.26%), Postives = 95/147 (64.63%), Query Frame = 3 
Query:   57 DIVDGQTKWLYNESGRYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKV 497
            D  D +T W+Y++SG+     VYAGL   + RAI D  R++G+L++GE    ++ N  V + Y YQV V       ++L WK+ +GKI+PEGAI GG D+  +LF+GR  I+G LLVGS+R D G +  G+ N VH + GCDILCKV
Sbjct:    2 DQTDNETDWVYSDSGKKVPGAVYAGLKSYIIRAIHDDQRIIGTLIDGEDFARVAYNGAVHKDYAYQVLVNTKTPDCSKLVWKFTTGKIIPEGAIRGGHDSSIMLFVGRAVINGELLVGSFRVDSGILYTGF-NSVHSVAGCDILCKV 147
[Close]
BLAST of SMED30001652 vs. Planmine SMEST
Match: SMESG000027124.1 (SMESG000027124.1)

HSP 1 Score: 117.472 bits (293), Expect = 1.775e-32
Identity = 58/148 (39.19%), Postives = 81/148 (54.73%), Query Frame = 3 
Query:   57 DIVDGQTKWLYNESGRYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKVS 500
            D VD +  W Y + G   +  VY G +  + RAI      +G+++ G+ C ++        +Y YQ+ VE  N      EWKW  G  +PEGAI+ G D   VLF+GR A +G+LL+GSYR D G + + YK  V    GCDILC+V 
Sbjct:   45 DEVDNKGMWQYGQKGEIPDKAVYGGCDSYIIRAIHKEQTFIGTIVRGDLCGHVPFRKWSHSKYIYQIMVENRNI----FEWKWTDGTFLPEGAIIAGEDNATVLFVGRAAYNGQLLIGSYRPDNGIVYLPYKGEVRERVGCDILCRVD 188
[Close]
BLAST of SMED30001652 vs. Planmine SMEST
Match: SMESG000029906.1 (SMESG000029906.1)

HSP 1 Score: 88.1965 bits (217), Expect = 1.388e-21
Identity = 44/137 (32.12%), Postives = 75/137 (54.74%), Query Frame = 3 
Query:   81 WLYNESGRYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILC 491
            W    +G    D+V AG N  +ARA+ +G  + G ++ GE C Y+  +       EY+V V+ +N      EWK + G ++P+G+++GGSD G  L+IGR  +  +LL G ++ + G   + Y ++ +     D+LC
Sbjct:   18 WQKASNGHIPNDSVNAG-NSYIARAVYNGEYIPGKIVRGENCAYICYDGKEISCSEYEVLVDTHNFGGQAYEWKSSRGSVIPKGSVIGGSDEGRPLYIGRARVADKLLAGKFQPEHGCTYIPYDSQENRKEDYDVLC 153
[Close]
BLAST of SMED30001652 vs. Planmine SMEST
Match: SMESG000074377.1 (SMESG000074377.1)

HSP 1 Score: 86.6557 bits (213), Expect = 4.918e-21
Identity = 50/143 (34.97%), Postives = 68/143 (47.55%), Query Frame = 3 
Query:   81 WLYNESGRYQEDTVYAGLNCRVARAICDGNRLVGSLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEGAIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCDILCKVSSES 509
            W    +G     TV AG  C V RA  +G  + G L EG K VY+S          Y+  VE N   N   +WK+  G  VP GAIVGG+D G  L+I R+ ++G  +VG Y    G     +    H   G ++LC V+  +
Sbjct:   18 WQKASNGEIPHRTVKAGGKCFVGRAQQNGQYIPGKLYEGHKGVYVSYGGKEICVNNYEALVETNVLHNDGFQWKYVDGNNVPSGAIVGGTDNGQPLYIARSEVNGEPVVGKYFPPHGCAYFPFGGEEHRKTGVEVLCCVAKSA 160
The following BLAST results are available for this feature:
BLAST of SMED30001652 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1W7RA662.636e-1232.59Methyltransferase-like protein OS=Hadrurus spadix ... [more]
A0A2I9LP565.889e-1230.82Methyltransferase-like protein OS=Centruroides hen... [more]
Q686R46.518e-1031.36CG10527-like methyltransferase (Fragment) OS=Mesob... [more]
Q686V27.449e-1031.36CG10527-like methyltransferase (Fragment) OS=Mesob... [more]
Q686U97.683e-1031.36CG10527-like methyltransferase (Fragment) OS=Mesob... [more]
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BLAST of SMED30001652 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30001652 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027142.16.427e-11499.37SMESG000027142.1[more]
SMESG000027140.11.992e-4246.26SMESG000027140.1[more]
SMESG000027124.11.775e-3239.19SMESG000027124.1[more]
SMESG000029906.11.388e-2132.12SMESG000029906.1[more]
SMESG000074377.14.918e-2134.97SMESG000074377.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001652 ID=SMED30001652|Name=SMED30001652|organism=Schmidtea mediterranea sexual|type=transcript|length=746bp
TCTACTGATGATCATCAAATAGACAAATTAGAATGAGTAATGATAAAAGG
TTAGGTGATATTGTTGATGGGCAAACAAAATGGTTATATAATGAAAGTGG
GAGGTATCAAGAAGACACTGTTTATGCCGGGTTGAATTGCCGCGTCGCAA
GAGCCATATGTGATGGTAACCGACTTGTCGGATCTCTTCTTGAAGGAGAA
AAATGTGTCTATCTAAGCTCCAACAATACCGTGTTTGAACAATATGAATA
TCAAGTGTTTGTAGAGGAAAACAATTGTAAAAATACCAGATTGGAATGGA
AATGGGCTTCTGGGAAAATTGTTCCAGAAGGAGCAATAGTAGGAGGCAGT
GACGCAGGCAACGTATTATTCATTGGGAGAACTGCAATTGATGGCAGACT
TTTAGTGGGCTCATATCGAGCAGATAAAGGGAAAATTACTGTTGGGTATA
AAAACAGAGTACATATTATACCTGGATGTGATATTTTGTGCAAGGTTTCA
AGTGAATCGTAGTACCGACATGACGTTTAGGCTGACTTGAAAATAATTTC
CTATGATAAATTTAAATCTTTACTTTTTATCGTAACAAAATCTAATACGT
CTTATTTAAATATTTTAAAAAGATAATTATTCTTTTCAGAAAATCTGTAG
CCAAACGGCAACAAAGCGAAATATAGATTTTATATGCAGTAATACAAAGT
TTATTTATAATTACAAATGCTCAATAAAGAATACATCCCTTTGTTA
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protein sequence of SMED30001652-orf-1

>SMED30001652-orf-1 ID=SMED30001652-orf-1|Name=SMED30001652-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=160bp
MSNDKRLGDIVDGQTKWLYNESGRYQEDTVYAGLNCRVARAICDGNRLVG
SLLEGEKCVYLSSNNTVFEQYEYQVFVEENNCKNTRLEWKWASGKIVPEG
AIVGGSDAGNVLFIGRTAIDGRLLVGSYRADKGKITVGYKNRVHIIPGCD
ILCKVSSES*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
Vocabulary: INTERPRO
TermDefinition
IPR006616DM9_repeat
IPR024518DUF3421
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0032259methylation