E3 ubiquitin-protein ligase MYLIP
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001636 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Match: MYLIP (myosin regulatory light chain interacting protein [Source:HGNC Symbol;Acc:HGNC:21155]) HSP 1 Score: 229.95 bits (585), Expect = 1.258e-67 Identity = 139/446 (31.17%), Postives = 247/446 (55.38%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASD------------------EVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ +++++++++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + PYR +VK+FV+PH IL ++TRH F+L K + G + S E+ + AL+ Q +FG+Y+ +T KY + ++ +EL S + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ +N +S S + ++++L L+E + C+VC + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGII-EVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKEALLAG--HLLCSPEQAVELSALLAQTKFGDYN--QNTAKYN--YEELCAKELSSATLNSIVAKHKELEGTSQASAEYQVLQIVS-AMENYGIEWHSVRDSEGQKLLIGVGPEGISICKDDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Match: MYLIP (myosin regulatory light chain interacting protein [Source:HGNC Symbol;Acc:HGNC:21155]) HSP 1 Score: 101.293 bits (251), Expect = 3.057e-23 Identity = 72/256 (28.12%), Postives = 127/256 (49.61%), Query Frame = 2
Query: 941 YGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASD------------------EVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ +N +S S + ++++L L+E + C+VC + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 4 YGIEWHSVRDSEGQKLLIGVGPEGISICKDDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 251
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Match: EPB41L5 (erythrocyte membrane protein band 4.1 like 5 [Source:HGNC Symbol;Acc:HGNC:19819]) HSP 1 Score: 83.9593 bits (206), Expect = 4.266e-16 Identity = 73/267 (27.34%), Postives = 123/267 (46.07%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G + T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTA--VQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Match: EPB41L5 (erythrocyte membrane protein band 4.1 like 5 [Source:HGNC Symbol;Acc:HGNC:19819]) HSP 1 Score: 83.5741 bits (205), Expect = 5.717e-16 Identity = 73/267 (27.34%), Postives = 123/267 (46.07%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G + T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTA--VQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Match: EPB41L5 (erythrocyte membrane protein band 4.1 like 5 [Source:HGNC Symbol;Acc:HGNC:19819]) HSP 1 Score: 83.5741 bits (205), Expect = 6.121e-16 Identity = 73/267 (27.34%), Postives = 123/267 (46.07%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G + T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTA--VQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93]) HSP 1 Score: 82.0333 bits (201), Expect = 4.311e-16 Identity = 74/271 (27.31%), Postives = 131/271 (48.34%), Query Frame = 2
Query: 332 SFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFV-QPHTILSDE-TRHQFYLQTKNHITEGCWN--HGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKI-LQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
SFD+ + V+C V L + + I + A+G EL ++V L + E +YFG QY + WL+ K+++QV + P+ F+VK+F +P + L +E TR+QF+LQ K I+ G H ++ E + A Q+E G+Y + + ALF + E +I + + + T + EL L W+ MYGV + + + + G+ P G+ F K GL ++++ + K++ ++ I V+ +D
Sbjct: 28 SFDTKKF----VQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDL-EERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIE----LAAFALQSELGDY---NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQT--PAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGL---FLWEKLQKLDFKNKKITLVVEED 281
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93]) HSP 1 Score: 82.0333 bits (201), Expect = 4.311e-16 Identity = 74/271 (27.31%), Postives = 131/271 (48.34%), Query Frame = 2
Query: 332 SFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFV-QPHTILSDE-TRHQFYLQTKNHITEGCWN--HGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKI-LQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
SFD+ + V+C V L + + I + A+G EL ++V L + E +YFG QY + WL+ K+++QV + P+ F+VK+F +P + L +E TR+QF+LQ K I+ G H ++ E + A Q+E G+Y + + ALF + E +I + + + T + EL L W+ MYGV + + + + G+ P G+ F K GL ++++ + K++ ++ I V+ +D
Sbjct: 28 SFDTKKF----VQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDL-EERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIE----LAAFALQSELGDY---NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQT--PAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGL---FLWEKLQKLDFKNKKITLVVEED 281
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93]) HSP 1 Score: 82.0333 bits (201), Expect = 4.311e-16 Identity = 74/271 (27.31%), Postives = 131/271 (48.34%), Query Frame = 2
Query: 332 SFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFV-QPHTILSDE-TRHQFYLQTKNHITEGCWN--HGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKI-LQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
SFD+ + V+C V L + + I + A+G EL ++V L + E +YFG QY + WL+ K+++QV + P+ F+VK+F +P + L +E TR+QF+LQ K I+ G H ++ E + A Q+E G+Y + + ALF + E +I + + + T + EL L W+ MYGV + + + + G+ P G+ F K GL ++++ + K++ ++ I V+ +D
Sbjct: 28 SFDTKKF----VQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDL-EERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIE----LAAFALQSELGDY---NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQT--PAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGL---FLWEKLQKLDFKNKKITLVVEED 281
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93]) HSP 1 Score: 82.0333 bits (201), Expect = 4.549e-16 Identity = 74/271 (27.31%), Postives = 131/271 (48.34%), Query Frame = 2
Query: 332 SFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFV-QPHTILSDE-TRHQFYLQTKNHITEGCWN--HGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKI-LQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
SFD+ + V+C V L + + I + A+G EL ++V L + E +YFG QY + WL+ K+++QV + P+ F+VK+F +P + L +E TR+QF+LQ K I+ G H ++ E + A Q+E G+Y + + ALF + E +I + + + T + EL L W+ MYGV + + + + G+ P G+ F K GL ++++ + K++ ++ I V+ +D
Sbjct: 44 SFDTKKF----VQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDL-EERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIE----LAAFALQSELGDY---NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQT--PAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGL---FLWEKLQKLDFKNKKITLVVEED 297
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Match: ptp-1 (Tyrosine-protein phosphatase 1 [Source:UniProtKB/Swiss-Prot;Acc:P28191]) HSP 1 Score: 68.5514 bits (166), Expect = 1.012e-11 Identity = 70/285 (24.56%), Postives = 121/285 (42.46%), Query Frame = 2
Query: 326 SNSFDSTRT-----------PTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQY----RGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCW--NHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDG 1126
SNS+D RT P + C V + +I+ ++G LL+KV L II E +YFG + Q+ WL+ + +Q+ + PY F+VK++V+ L DE TR QFY Q + ++ EG N G L + + + QAE G++ + M KI L ++ + H T E L MYG+ YD D ++ G+G G+ + + +++ + + K++ + + ++ +DG
Sbjct: 5 SNSYDVQRTEAIGQTPVKTPPPNQIRCTVTFLDSTSYHFEIEKNSLGIVLLEKVFNYLEII-EKDYFGLVFIAVDNSSAQQKKWLDPSKNLRKQM-ICPPYHLFFRVKFYVRDPNRLRDEFTRFQFYQQVRQNLEEGRLPCNEG----SLALLASYVVQAEVGDFEEKTHGMSRTCLCYKIQFATLPDDFSDRVAELHQLHIGQTPDVAEQNFLDHARR-LEMYGMDVYDGVDANHLPIEIGVGAVGIKVFHEGIKM-NEYAWVRIRKLSFKKKQFQVLVANEDG 281
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Match: yrt (gene:FBgn0004049 transcript:FBtr0114375) HSP 1 Score: 86.2705 bits (212), Expect = 4.026e-17 Identity = 75/270 (27.78%), Postives = 129/270 (47.78%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
++C V L ++ + I++ +A+G L ++V L II E +YFG Q+ WL+ I +QV + PY F KVK++ +P+T+ + TR+ F+LQ K + EG C + ELC AL Q+E G+Y HS ++ ++ + + E+ +I I D + + T + E L WL MYGV + + G+ P G+ F K GL + + ++K++ + + ++I+DD R Q
Sbjct: 58 IDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDII-EKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKAT--ELC---ALALQSELGDYDNQEHSAATVSEF-----RFVPEQTEDLEIA-ILDEYKTCRGLTPAQAETAFLN--KAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGL---FFWPKISKLDFKKKKLTLIVIEDDDEGREQ 310
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Match: yrt (gene:FBgn0004049 transcript:FBtr0114374) HSP 1 Score: 86.2705 bits (212), Expect = 4.726e-17 Identity = 75/270 (27.78%), Postives = 129/270 (47.78%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
++C V L ++ + I++ +A+G L ++V L II E +YFG Q+ WL+ I +QV + PY F KVK++ +P+T+ + TR+ F+LQ K + EG C + ELC AL Q+E G+Y HS ++ ++ + + E+ +I I D + + T + E L WL MYGV + + G+ P G+ F K GL + + ++K++ + + ++I+DD R Q
Sbjct: 58 IDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDII-EKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKAT--ELC---ALALQSELGDYDNQEHSAATVSEF-----RFVPEQTEDLEI-AILDEYKTCRGLTPAQAETAFLN--KAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGL---FFWPKISKLDFKKKKLTLIVIEDDDEGREQ 310
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Match: yrt (gene:FBgn0004049 transcript:FBtr0082793) HSP 1 Score: 86.2705 bits (212), Expect = 5.099e-17 Identity = 75/270 (27.78%), Postives = 129/270 (47.78%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
++C V L ++ + I++ +A+G L ++V L II E +YFG Q+ WL+ I +QV + PY F KVK++ +P+T+ + TR+ F+LQ K + EG C + ELC AL Q+E G+Y HS ++ ++ + + E+ +I I D + + T + E L WL MYGV + + G+ P G+ F K GL + + ++K++ + + ++I+DD R Q
Sbjct: 58 IDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDII-EKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKAT--ELC---ALALQSELGDYDNQEHSAATVSEF-----RFVPEQTEDLEI-AILDEYKTCRGLTPAQAETAFLN--KAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGL---FFWPKISKLDFKKKKLTLIVIEDDDEGREQ 310
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Match: yrt (gene:FBgn0004049 transcript:FBtr0114376) HSP 1 Score: 85.5001 bits (210), Expect = 6.911e-17 Identity = 75/270 (27.78%), Postives = 129/270 (47.78%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
++C V L ++ + I++ +A+G L ++V L II E +YFG Q+ WL+ I +QV + PY F KVK++ +P+T+ + TR+ F+LQ K + EG C + ELC AL Q+E G+Y HS ++ ++ + + E+ +I I D + + T + E L WL MYGV + + G+ P G+ F K GL + + ++K++ + + ++I+DD R Q
Sbjct: 58 IDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDII-EKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKAT--ELC---ALALQSELGDYDNQEHSAATVSEF-----RFVPEQTEDLEI-AILDEYKTCRGLTPAQAETAFLN--KAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGL---FFWPKISKLDFKKKKLTLIVIEDDDEGREQ 310
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Match: dnr1 (gene:FBgn0260866 transcript:FBtr0330229) HSP 1 Score: 75.0998 bits (183), Expect = 1.021e-13 Identity = 40/113 (35.40%), Postives = 62/113 (54.87%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQY----RGKYQEPLWLNIRNKI---SRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEG 688
C VNLPN + D +A GQE L+KVC+ + II E EYFG ++ + + Q W+N+RN++ S + +VK++V H IL + R+ FY+Q + + EG
Sbjct: 3 CIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRNRLSGDSGSSGSGIQLMLALRVKFWVPVHFILQESVRNLFYMQARRDLLEG 115 HSP 2 Score: 55.0694 bits (131), Expect = 1.737e-7 Identity = 22/41 (53.66%), Postives = 28/41 (68.29%), Query Frame = 2
Query: 1490 VQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQI 1612
+QC +C DR IN VF PC H++ C CAAR + CP CR +I
Sbjct: 546 MQCKICMDRAINTVFNPCCHVIACAQCAARCSNCPNCRVKI 586
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Match: mylipa (myosin regulatory light chain interacting protein a [Source:NCBI gene;Acc:335888]) HSP 1 Score: 225.713 bits (574), Expect = 5.151e-66 Identity = 138/436 (31.65%), Postives = 242/436 (55.50%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXX--------XXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C V P+ +++I++D++A G++ L+KVC+KLGII E +YFG Q+ G E LWLN+RN+IS+Q+ + P R +VK+FV+PH IL ++TRH F++ K + G + + +E+ + AL+ QAEFG+Y+ +T KY ++ ++ E T I I H L+ +Q +EY+ L+L++ S YGV ++ D ++ L G+GP+G+ +C F L+++ + + + + + + ++ + F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR S +P+N++ Q+ + + K ++ L+ C++C + +I+ F PC H+VCC+ CAA+L CP+CR++++ H Y
Sbjct: 3 CHVTRPDAVVMEIEVDAKANGEDCLNKVCRKLGII-EVDYFGLQFSGSKGENLWLNLRNRISQQMDNLTPCRLRLRVKFFVEPHLILQEQTRHLFFMHVKEDLHRG--HLRMCSEQAQELSALLAQAEFGDYN--QNTAKY--WYTELCGSEPNQTTINSIIAKHKALEGLSQASVEYQALQLVS-SLEHYGVEWHWARDAEAQRLAIGVGPEGIAICRDDFSLVNRISYPIIQIATQSGKSVYLTVTKESSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENINLGKKYVFDIRRTSKEVYDYARRALYNAGIVDMMSRPGERTPSNRSPSREQEGALDCGGCQQSRLLQEKLQKLREALL-CMLCCEEEIDAAFCPCGHMVCCQNCAAQLQSCPVCRSEVEHVQHVY 429
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Match: mylipb (myosin regulatory light chain interacting protein b [Source:NCBI gene;Acc:565911]) HSP 1 Score: 216.468 bits (550), Expect = 1.090e-62 Identity = 132/432 (30.56%), Postives = 233/432 (53.94%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCD----TVDVDILKDCKT--ITHFFRKS-NTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQ----CVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C + P+ ++++++D +A G+++L+K+CQK+GII E +YFG Q+ G E LW+N+RN+I ++V + P R +VK+FV+PH IL ++TRH F + K I +G + E+ + AL+ QAEFG+Y +T KY + +I ++ I I H +L+ +Q EY+ L+L++ S YGV ++ D + L G+G +GLF+C + F I++ ++ + + R + + +D+G + F S A+ L+R +TE F++CD TV + +D K + F +S + + Y +DI +T KEVYD RR ++ + + + ++K + V L+ + +Q C +C +++I+ F PC H+ CC CA++L CP+CR+++ H Y
Sbjct: 3 CHITRPDSVVLEVEVDPKANGEDILNKICQKMGII-EVDYFGLQFTGTKGESLWMNLRNRICQEVDCVSPCRLRLRVKFFVEPHLILQEQTRHLFLMHVKEEIIKGSLR--LDAEQAIELCALLAQAEFGDYK--QNTAKYC--YSQIYGQDPSHDTINTISLKHKSLEGVSQASAEYQALQLVS-SLTYYGVEWHFARDSEGQELLIGVGQEGLFVCKSDFTPIERLMYPVIQMATQSGRNVYVTITKDNGDSVVLLFKFVSPSAANGLYRAITEIHAFYRCDTVMSTVKMQYSRDFKGHLASLFLNESIDLGKRYIFDIQRTSKEVYDRTRRALFNAGVSVNGRGISRSPLRKTKVDREERMCVDCRETHVLKEKLQRLQEALTCALCCEQEISAAFCPCGHMFCCYNCASQLQCCPVCRSEVDRVQHVY 426
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 75.485 bits (184), Expect = 1.354e-13 Identity = 65/267 (24.34%), Postives = 120/267 (44.94%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A G EL +++ L ++ E +YFG ++ Q P WL++ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + + QAE G+Y H ++ F P T+ ++ ++ + Q + E+ L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGAELFEQIMYHLDVV-EKDYFGLRFMDSAQVPHWLDVTKSIKKQVKIGPPYCLHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFDT--TVELASYALQAELGDYDPAEHGLDLVSEFR-FIPN-------QTEDMEVAIYNAWKECRGQTPAQAEINYLNKAKWLEMYGVDMHMVKARDGNEYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKCKLTLVVVEDDEQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 75.0998 bits (183), Expect = 1.409e-13 Identity = 64/261 (24.52%), Postives = 118/261 (45.21%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDD 1123
+ C V+L + + +D+ +A G EL +++ L ++ E +YFG ++ Q P WL++ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + + QAE G+Y H ++ F P T+ ++ ++ + Q + E+ L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGAELFEQIMYHLDVV-EKDYFGLRFMDSAQVPHWLDVTKSIKKQVKIGPPYCLHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFDT--TVELASYALQAELGDYDPAEHGLDLVSEFR-FIPN-------QTEDMEVAIYNAWKECRGQTPAQAEINYLNKAKWLEMYGVDMHMVKARDGNEYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKCKLTLVVVEDD 289
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 74.7146 bits (182), Expect = 2.076e-13 Identity = 64/261 (24.52%), Postives = 118/261 (45.21%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDD 1123
+ C V+L + + +D+ +A G EL +++ L ++ E +YFG ++ Q P WL++ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + + QAE G+Y H ++ F P T+ ++ ++ + Q + E+ L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGAELFEQIMYHLDVV-EKDYFGLRFMDSAQVPHWLDVTKSIKKQVKIGPPYCLHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFDT--TVELASYALQAELGDYDPAEHGLDLVSEFR-FIP-------NQTEDMEVAIYNAWKECRGQTPAQAEINYLNKAKWLEMYGVDMHMVKARDGNEYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKCKLTLVVVEDD 289
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Match: rbm42 (RNA binding motif protein 42 [Source:Xenbase;Acc:XB-GENE-5896695]) HSP 1 Score: 224.942 bits (572), Expect = 6.454e-66 Identity = 134/438 (30.59%), Postives = 245/438 (55.94%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKS--NTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQA----------SDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ ++++++D++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + P+R KVK+FV+PH IL ++TRH F+L K + G S + + AL+ Q E+G+Y ++T Y+L + +++ + ++ I H +L+ +Q EY+ L++++ + YGV ++ + D + L GIGP+G+ LC F I++ + + + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + FF N + Y +DI +T KEVYD ARR Y+ + + + ++S++ S + ++++L L+E + C++C + +IN F PC H+VCCE CA +L CP+CR ++ H +
Sbjct: 3 CYVTRPDAVVMEVEVDAKANGEDCLNQVCKRLGII-EGDYFGLQFSGNKGENLWLNLRNRISQQMDGLAPFRLKLKVKFFVEPHLILQEQTRHMFFLHIKEDLLAGRLQ--CSPAQAVELSALLAQMEYGDYSVNTAT--YSL--QDLCGKDIDTAALESIIAKHKSLEGLSQASGEYQFLQIVS-TLENYGVEWHSVRDAEGQKLIVGIGPEGISLCKEDFSPINRITYPVIQMATQSGKNVYLTITKESGNSLVLLFKVVSTRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDLKGHLASFFLNDNINVGKKYVFDIRRTSKEVYDHARRALYNAGIVDLVSGSGHSEPSSPLKTSESNMNCNSCESLSCQQTKALQEKLRKLKEAMLCMLCCEEEINSAFCPCGHMVCCEGCATQLQSCPVCRASVEHVQHVF 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Match: rbm42 (RNA binding motif protein 42 [Source:Xenbase;Acc:XB-GENE-5896695]) HSP 1 Score: 123.25 bits (308), Expect = 5.333e-32 Identity = 55/138 (39.86%), Postives = 92/138 (66.67%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSST 784
C+V P+ ++++++D++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + P+R KVK+FV+PH IL ++TRH F+L K + G S + + AL+ Q E+G+Y ++T
Sbjct: 3 CYVTRPDAVVMEVEVDAKANGEDCLNQVCKRLGII-EGDYFGLQFSGNKGENLWLNLRNRISQQMDGLAPFRLKLKVKFFVEPHLILQEQTRHMFFLHIKEDLLAGRLQ--CSPAQAVELSALLAQMEYGDYSVNTAT 137
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Match: ptpn21 (protein tyrosine phosphatase non-receptor type 21 [Source:NCBI gene;Acc:100127697]) HSP 1 Score: 70.8626 bits (172), Expect = 1.757e-12 Identity = 69/245 (28.16%), Postives = 108/245 (44.08%), Query Frame = 2
Query: 317 LPISNSFDSTRTPTVTVE-CFV---NLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQV-PLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSST---MKYALFWPKILQEELGSTDIQK-IRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFL 1021
LP TR TV+ + C V L N++ ++ + + GQE L+ V Q+L + E YF Y K + W+++ + +Q+ L F V Y+V + L E TR+Q+YLQ K I EG + E+ + L QA+FG+Y + S +YALF +Q+E + K + H L+ + E ++ I E YG Y D L G G+F+
Sbjct: 3 LPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESSGQECLEAVAQRLEL-REVTYFSLWYYNKQNQQRWVDLEKPLKKQLDKYALEPTVYFGVVYYVPSVSQLQQEITRYQYYLQLKKDILEG--KIPCTLEQTVQLAGLAVQADFGDYDQYESQDFLQRYALFPVGWIQDEKTLEEATKNVALLHQKLRGLSPPDAELLYMQEI-EKLENYGDESYPAKDSQGTDLCIGACLSGIFV 243
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Match: muc6 (mucin 6, oligomeric mucus/gel-forming [Source:Xenbase;Acc:XB-GENE-987881]) HSP 1 Score: 71.2478 bits (173), Expect = 4.436e-12 Identity = 62/239 (25.94%), Postives = 109/239 (45.61%), Query Frame = 2
Query: 377 VNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSST--MKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNC 1084
V + ++ + +++ RA G+ LLD VC L ++ E +YFG +++ + +WL++ I +Q+ F VK+F HT L +E TR+ F LQ K + +G S+ L +I+ + Q+E G++ ++ + P+ QE L +KI + H N T + +++LL I MYGV + D + + G+ VF TK+N
Sbjct: 44 VQMLDETLETVEVPIRAPGKALLDAVCSHLNLV-EGDYFGLEFQDHRKIMVWLDLLKPIVKQIRRPKNVVLKFVVKFFPPDHTQLQEELTRYLFALQVKQDLVQGKLTCNESSAAL--LISHIVQSEIGDFDEAGDQDHLQKNKYMPQ--QEPLE----EKIMELHRNHFGQTPAESDFQLLE-IARRLEMYGVRLHPAKDREGTKINLAVANTGIL------------VFQGHTKINA 260
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Match: muc6 (mucin 6, oligomeric mucus/gel-forming [Source:Xenbase;Acc:XB-GENE-987881]) HSP 1 Score: 70.8626 bits (172), Expect = 5.843e-12 Identity = 62/239 (25.94%), Postives = 109/239 (45.61%), Query Frame = 2
Query: 377 VNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSST--MKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNC 1084
V + ++ + +++ RA G+ LLD VC L ++ E +YFG +++ + +WL++ I +Q+ F VK+F HT L +E TR+ F LQ K + +G S+ L +I+ + Q+E G++ ++ + P+ QE L +KI + H N T + +++LL I MYGV + D + + G+ VF TK+N
Sbjct: 44 VQMLDETLETVEVPIRAPGKALLDAVCSHLNLV-EGDYFGLEFQDHRKIMVWLDLLKPIVKQIRRPKNVVLKFVVKFFPPDHTQLQEELTRYLFALQVKQDLVQGKLTCNESSAAL--LISHIVQSEIGDFDEAGDQDHLQKNKYMPQ--QEPLE----EKIMELHRNHFGQTPAESDFQLLE-IARRLEMYGVRLHPAKDREGTKINLAVANTGIL------------VFQGHTKINA 260
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Match: Mylip (myosin regulatory light chain interacting protein [Source:MGI Symbol;Acc:MGI:2388271]) HSP 1 Score: 225.328 bits (573), Expect = 4.184e-66 Identity = 136/446 (30.49%), Postives = 248/446 (55.61%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQA------------------SDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ +++++++++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + PYR +VK+FV+PH IL ++TRH F+L K + G S E+ + AL+ Q +FG+Y+ +T +Y+ + + ++EL S+ + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ ++ +S + S + ++++L L+E + C+ C + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGII-EVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKESLLAGHLQ--CSPEQAVELSALLAQTKFGDYN--QNTAQYS--YEDLCEKELSSSTLNSIVAKHKELEGISQASAEYQVLQIVS-AMENYGIEWHAVRDSEGQKLLIGVGPEGISICKEDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRSDQSPPSSPLKSSDSSMSCSSCEGLSCQQTRVLQEKLRKLKEAMLCMACCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Match: Mylip (myosin regulatory light chain interacting protein [Source:MGI Symbol;Acc:MGI:2388271]) HSP 1 Score: 160.999 bits (406), Expect = 3.272e-43 Identity = 108/379 (28.50%), Postives = 197/379 (51.98%), Query Frame = 2
Query: 572 ILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQA------------------SDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
+ PYR +VK+FV+PH IL ++TRH F+L K + G S E+ + AL+ Q +FG+Y+ +T +Y+ + + ++EL S+ + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ ++ +S + S + ++++L L+E + C+ C + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 4 LAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKESLLAGHLQ--CSPEQAVELSALLAQTKFGDYN--QNTAQYS--YEDLCEKELSSSTLNSIVAKHKELEGISQASAEYQVLQIVS-AMENYGIEWHAVRDSEGQKLLIGVGPEGISICKEDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRSDQSPPSSPLKSSDSSMSCSSCEGLSCQQTRVLQEKLRKLKEAMLCMACCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 367
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Match: Epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:MGI Symbol;Acc:MGI:103006]) HSP 1 Score: 83.5741 bits (205), Expect = 3.353e-16 Identity = 73/267 (27.34%), Postives = 122/267 (45.69%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTA--VQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Match: Epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:MGI Symbol;Acc:MGI:103006]) HSP 1 Score: 83.5741 bits (205), Expect = 3.439e-16 Identity = 73/267 (27.34%), Postives = 122/267 (45.69%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDTA--VQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Match: Epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:MGI Symbol;Acc:MGI:103006]) HSP 1 Score: 80.8777 bits (198), Expect = 1.584e-15 Identity = 73/267 (27.34%), Postives = 122/267 (45.69%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+ C V+L + + +D+ +A GQEL D++ L +I ES+YFG ++ Q WL+ I +QV + PY +VK++ +P+ + + TR+ F LQ K I G T + A QAE G+Y HS ++ F P I EE+ +K +++ Q + E L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 43 ITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLI-ESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLECPFDT--AVQLAAYNLQAELGDYDLAEHSPELVSEFR-FVP-IQTEEMELAIFEKWKEYRG------QTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGL---FFWPKITRLDFKKNKLTLVVVEDDDQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Match: sp|Q8WY64|MYLIP_HUMAN (E3 ubiquitin-protein ligase MYLIP OS=Homo sapiens OX=9606 GN=MYLIP PE=1 SV=2) HSP 1 Score: 229.95 bits (585), Expect = 6.040e-67 Identity = 139/446 (31.17%), Postives = 247/446 (55.38%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASD------------------EVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ +++++++++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + PYR +VK+FV+PH IL ++TRH F+L K + G + S E+ + AL+ Q +FG+Y+ +T KY + ++ +EL S + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ +N +S S + ++++L L+E + C+VC + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGII-EVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKEALLAG--HLLCSPEQAVELSALLAQTKFGDYN--QNTAKYN--YEELCAKELSSATLNSIVAKHKELEGTSQASAEYQVLQIVS-AMENYGIEWHSVRDSEGQKLLIGVGPEGISICKDDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Match: sp|D3ZDI6|MYLIP_RAT (E3 ubiquitin-protein ligase MYLIP OS=Rattus norvegicus OX=10116 GN=Mylip PE=2 SV=1) HSP 1 Score: 229.18 bits (583), Expect = 1.162e-66 Identity = 138/446 (30.94%), Postives = 249/446 (55.83%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQA------------------SDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ +++++++++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + PYR +VK+FV+PH IL ++TRH F+L K + G S E+ + AL+ Q +FG+Y+ +T +Y+ + + ++EL S+ + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ +N +S + S + ++++L L+E + C+VC + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGII-EVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKESLLAGHLQ--CSPEQAVELSALLAQTKFGDYN--QNTAQYS--YEDLCEKELSSSTLNSIVGKHKELEGISQASAEYQVLQIVS-AMENYGIEWHAVRDSEGQKLLIGVGPEGISICKEDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRNDQSPPSSPLKSSDSSMSCSSCEGLSCQQTRVLQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Match: sp|Q8BM54|MYLIP_MOUSE (E3 ubiquitin-protein ligase MYLIP OS=Mus musculus OX=10090 GN=Mylip PE=1 SV=1) HSP 1 Score: 225.328 bits (573), Expect = 2.927e-65 Identity = 136/446 (30.49%), Postives = 248/446 (55.61%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQA------------------SDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C+V P+ +++++++++A G++ L++VC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + PYR +VK+FV+PH IL ++TRH F+L K + G S E+ + AL+ Q +FG+Y+ +T +Y+ + + ++EL S+ + I H L+ +Q EY++L++++ + YG+ ++ + D + L G+GP+G+ +C F I++ + V + + + + ++ G++ F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ D++ ++ +S + S + ++++L L+E + C+ C + +IN F PC H VCCE CAA+L CP+CR++++ H Y
Sbjct: 3 CYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGII-EVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKESLLAGHLQ--CSPEQAVELSALLAQTKFGDYN--QNTAQYS--YEDLCEKELSSSTLNSIVAKHKELEGISQASAEYQVLQIVS-AMENYGIEWHAVRDSEGQKLLIGVGPEGISICKEDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSKEVYDHARRALYNAGVV--------DLVSRSDQSPPSSPLKSSDSSMSCSSCEGLSCQQTRVLQEKLRKLKEAMLCMACCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVY 432
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Match: sp|Q6TEM9|MYLIA_DANRE (E3 ubiquitin-protein ligase MYLIP-A OS=Danio rerio OX=7955 GN=mylipa PE=1 SV=2) HSP 1 Score: 225.713 bits (574), Expect = 3.888e-65 Identity = 138/436 (31.65%), Postives = 242/436 (55.50%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXX--------XXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C V P+ +++I++D++A G++ L+KVC+KLGII E +YFG Q+ G E LWLN+RN+IS+Q+ + P R +VK+FV+PH IL ++TRH F++ K + G + + +E+ + AL+ QAEFG+Y+ +T KY ++ ++ E T I I H L+ +Q +EY+ L+L++ S YGV ++ D ++ L G+GP+G+ +C F L+++ + + + + + + ++ + F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR S +P+N++ Q+ + + K ++ L+ C++C + +I+ F PC H+VCC+ CAA+L CP+CR++++ H Y
Sbjct: 3 CHVTRPDAVVMEIEVDAKANGEDCLNKVCRKLGII-EVDYFGLQFSGSKGENLWLNLRNRISQQMDNLTPCRLRLRVKFFVEPHLILQEQTRHLFFMHVKEDLHRG--HLRMCSEQAQELSALLAQAEFGDYN--QNTAKY--WYTELCGSEPNQTTINSIIAKHKALEGLSQASVEYQALQLVS-SLEHYGVEWHWARDAEAQRLAIGVGPEGIAICRDDFSLVNRISYPIIQIATQSGKSVYLTVTKESSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENINLGKKYVFDIRRTSKEVYDYARRALYNAGIVDMMSRPGERTPSNRSPSREQEGALDCGGCQQSRLLQEKLQKLREALL-CMLCCEEEIDAAFCPCGHMVCCQNCAAQLQSCPVCRSEVEHVQHVY 429
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Match: sp|Q05AK5|MYLIB_DANRE (E3 ubiquitin-protein ligase MYLIP-B OS=Danio rerio OX=7955 GN=mylipb PE=2 SV=1) HSP 1 Score: 216.083 bits (549), Expect = 1.098e-61 Identity = 131/432 (30.32%), Postives = 234/432 (54.17%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCD----TVDVDILKDCKT--ITHFFRKS-NTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQ----CVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C + P+ ++++++D +A G+++L+K+CQK+GII E +YFG Q+ G E LW+N+RN+I ++V + P R +VK+FV+PH IL ++TRH F + K I +G + E+ + AL+ QAEFG+Y +T KY + +I ++ I I H +L+ +Q EY+ L+L++ S YGV ++ D + L G+G +GLF+C + F I++ ++ + + R + + +D+G + F S A+ L+R +TE F++CD TV + +D K + F +S + + Y +DI +T KEVYD RR ++ + + + ++++ + V L+ + +Q C +C +++I+ F PC H+ CC CA++L CP+CR+++ H Y
Sbjct: 3 CHITRPDSVVLEVEVDPKANGEDILNKICQKMGII-EVDYFGLQFTGTKGESLWMNLRNRICQEVDCVSPCRLRLRVKFFVEPHLILQEQTRHLFLMHVKEEIIKGSLR--LDAEQAIELCALLAQAEFGDYK--QNTAKYC--YSQIYGQDPSHDTINTISLKHKSLEGVSQASAEYQALQLVS-SLTYYGVEWHFARDSEGQQLLIGVGQEGLFVCKSDFTPIERLMYPVIQMATQSGRNVYVTITKDNGDSVVLLFKFVSPSAANGLYRAITEIHAFYRCDTVMSTVKMQYSRDFKGHLASLFLNESIDLGKRYIFDIQRTSKEVYDRTRRALFNAGVSVNGRGISRSLLRQTKVDREERMCVDCRETHVLKEKLQRLQEALTCALCCEQEISAAFCPCGHMFCCYNCASQLQCCPVCRSEVDRVQHVY 426
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Match: A0A0X3NUC5 (E3 ubiquitin-protein ligase MYLIP OS=Schistocephalus solidus OX=70667 GN=MYLIP PE=4 SV=1) HSP 1 Score: 276.174 bits (705), Expect = 1.141e-78 Identity = 166/466 (35.62%), Postives = 253/466 (54.29%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDILKDC-----KTITHFFRKSNTCRSYFYDIVKTQKEVYDXXXX-----------------XXXXXXXXXXPTNQANDVIQKNPESSQAS----DEVVVXXXXXXXX-----------XXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISD 1651
V C+V P++ + +++D +A GQE+LDK+C+ LGII ESEYFG QY G + +WLN+RN+ISRQ+P PY KVKYFV PHT+L + TRHQFYL +T G W+ +S E ++ALMT +FG+++ ++ KYA FW +EE+ + I+ +H L + ++ EYELLR+ + YG+ +Y++ D + + L G+GP+ + +C T I+K+ + + V T+RV+ L++DDGS + + F +A+ SL+R +TE FF CD V D+L+ +T+T FF + + Y +D+ T +EVYD ARR + +S P + +N + A E V+ LRE + C VC D IN VF PC H +CC+ CA R++QCPICR I++ H + W S+
Sbjct: 31 VTCYVTQPDNHVFHVEVDHKAEGQEVLDKICRMLGIIDESEYFGIQYAGLKGDLIWLNMRNRISRQLPGTPPYHLFIKVKYFVPPHTLLLEGTRHQFYLNVAQQLTRGLWDADMSVELHARLVALMTYVQFGSFNPSTTPCKYACFWSD-RREEISAEFIRLAASYHKELNEMPTQQAEYELLRIAHLEVPAYGLYYYEVKDMFDRRLLIGVGPEFVAVCATDTSFIEKYPYCRLQTVTVTNRVVTLNLLEDDGSVKSRPFQLTCIRAANSLYRSITEVHCFFLCDNVREDVLQQTNRDLRETLTSFF--DHNSKDYAFDVRLTCREVYDRARRRLYNTSTGVFALTPGTDASPGEASTIDPLSSSNGALSIGVSGGAARPRKHSETVISHPGSAASIEEFHEAVQEQLREALVCRVCMDSPINCVFFPCGHTICCKDCADRVDQCPICRKSIELRHPCFLPWDSE 493
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Match: A0A4V3SFE5 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004381 PE=4 SV=1) HSP 1 Score: 271.937 bits (694), Expect = 4.635e-78 Identity = 156/461 (33.84%), Postives = 255/461 (55.31%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDILKDCKT-ITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXP-----------------------TNQ------ANDVIQKN--PESSQASDEVVVXXXXXXXXXXXXVQCVVCK---DRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKW 1642
V C+V+ ++ +++++++ RA+GQ++LDK+C++LGI+ E+EYFG Q+ G E LW+N RN++S+Q+ PY F F+VK+F+ P IL + TRHQFY+ + EG W+ ++ + H+IALM +FG Y+ ++ KYA FWP + E+ I + H L +T + ++YELLRL YG+ FY++ D + + L FG+GP+GL LC T + + DK+ + V + + RV+ L++DDGS + + + S + + SL+R V E + FF+CD+V ++L + I + + Y +D+ T +EVYD ARR Y +SN +P TN+ + DV + E S +D V + + + + L + +C+ D I+RVF+PC HI+CC CA R+ QC +CR I H + W
Sbjct: 33 VICYVSHADNSVLQVEVEHRAVGQDVLDKICRELGIVEEAEYFGIQFVGNKNEILWVNNRNRLSKQLSSSPPYHFYFRVKFFIPPEDILLEGTRHQFYINVVRQLKEGVWDAEMNLQTQAHLIALMAYVQFGKYNQNTTPCKYACFWPDS-RGEIPPDAIGLAANFHRALDGFTIQHVQYELLRLAATEVPSYGMHFYEVKDIFERRLTFGVGPEGLVLCNTNYTIDDKFPYCRVQTITTSSRVVTLNLLEDDGSVKARNYQLASPRLASSLYRLVNEVYAFFRCDSVRKEVLSQTRRDILDAISFHHNGKEYAFDVRYTSREVYDRARRHLYHCTSNTAPHESPPNYPGMISGSLGDPSNLSSTNELGAHRASGDVGLGSLKREYSSRADSFVTDEELQEIVQKCLWEIGLCRICVDAPISRVFLPCGHIICCVDCAERIEQCSVCRQDIMERHQCFLPW 492
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Match: A0A183TJF5 (E3 ubiquitin-protein ligase MYLIP OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS16603 PE=4 SV=1) HSP 1 Score: 274.633 bits (701), Expect = 6.199e-78 Identity = 166/475 (34.95%), Postives = 253/475 (53.26%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDILKDC-----KTITHFFR---------KSNTCRSYFYDIVKTQKEVYDXXXX-----------------XXXXXXXXXXPTNQANDVIQKNPESSQAS----DEVVVXXXXXXXX-----------XXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISD 1651
V C+V P++ + +++D +A GQE+LDK+C+ LGII ESEYFG QY G + +WLN+RN+ISRQ+P PY KVKYFV PHT+L + TRHQFYL +T G W+ +S E ++ALMT +FG+++ ++ KYA FW +EE+ + I+ +H L + ++ EYELLR+ + YG+ +Y++ D + + L G+GP+ + +C T I+K+ + + V T+RV+ L++DDGS + + F +A+ SL+R +TE FF CD V D+L+ +T+T FF + + Y +D+ T +EVYD ARR + +S P + +N + A E V+ LRE + C VC D IN VF PC H +CC+ CA R++QCPICR I++ H + W S+
Sbjct: 36 VTCYVTQPDNHVFHVEVDHKAEGQEVLDKICRMLGIIDESEYFGIQYAGLKGDLIWLNMRNRISRQLPGTPPYHLFIKVKYFVPPHTLLLEGTRHQFYLNVAQQLTRGLWDADMSVELHARLVALMTYVQFGSFNPSTTPCKYACFWSD-RREEISAEFIRLAASYHKELNEMPTQQAEYELLRIAHLEVPAYGLYYYEVKDMFDRRLLIGVGPEFVAVCATDTSFIEKYPYCRLQTVTVTNRVVTLNLLEDDGSVKSRPFQLTCIRAANSLYRSITEVHCFFLCDNVREDVLQQTNRDLRETLTSFFDHNCKLPVVFSAGAAKDYAFDVRLTCREVYDRARRRLYNTSTGVFALTPGTDASPGEASTIDPLSSSNGALSIGVSGGAARPRKHSETVISHPGSAASIEEFHEAVQEQLREALVCRVCMDSPINCVFFPCGHTICCKDCADRVDQCPICRKSIELRHPCFLPWDSE 509
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Match: A0A4E0RY14 (E3 ubiquitin-protein ligase MYLIP-A OS=Fasciola hepatica OX=6192 GN=D915_000652 PE=4 SV=1) HSP 1 Score: 271.166 bits (692), Expect = 9.987e-78 Identity = 155/468 (33.12%), Postives = 257/468 (54.91%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCK-TITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXP-------------------TNQANDVIQKNP------------ESSQASDEVVVXXXXXXXXXXXXVQ---CVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDEN 1657
C++ ++ + ++++ +A GQE+LDK+C+ LGI+ E+EYFG Q+ G E LWLN RN++S+QVP PY F+VKY+V PH IL ++TR+QFY + G W+ + E ++IALM +FG Y++ ++ KYA FWP + E+ I+ + H +L +T +YELLR+++ + YG FY++ D + + L G+GP+GL LC++ +I+++ + V V + RV+ L++DDGS + + + + + + SL+R +TE FF+CD+V +L +D K + F + + Y +D+ T +EVYD ARR Y +SN SP ++ D +Q++ E S ++ +V + + L + C +C D I+RVF PC HI+CC CA R+ +C ICR I++ H + W +DE+
Sbjct: 37 CYITQADNNVFHVEVEHKADGQEVLDKICKMLGIMDEAEYFGVQFMGLKNEMLWLNNRNRLSKQVPGSSPYHLYFRVKYYVPPHAILLEDTRNQFYNNVVQQLKGGVWDAESTLETQANLIALMAYTQFGPYNANTTPCKYACFWPDC-RGEIPPEAIRMAANFHRDLDGFTVSHAKYELLRIVSMEFPSYGTHFYEVKDIFDRKLLLGVGPEGLALCSSHTSVIERFPYCRVHTVTTSARVVTLNLLEDDGSVKGRNYQLATNRLASSLYRSITEIHAFFRCDSVRDTVLWQTTRDLKDALVSIFDHNG--KDYAFDVRYTFREVYDRARRHLYHCTSNTSPRGSPLNHAGIVLNNDESIASSSGGDALQRSSGDNASTAGGLKREYSSRAESIVSTEEVQEIVQERLREVGICRLCMDAPISRVFFPCGHIICCATCADRVEECSICRKPIELRHPCFLPWSADED 501
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Match: A0A504Z9P0 (E3 ubiquitin-protein ligase MYLIP-A OS=Fasciola gigantica OX=46835 GN=FGIG_03246 PE=4 SV=1) HSP 1 Score: 270.011 bits (689), Expect = 2.623e-77 Identity = 156/468 (33.33%), Postives = 257/468 (54.91%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCK-TITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXX----XXXXXXXXXPTNQANDVIQKNPE--SSQASD------------------------EVVVXXXXXXXXXXXXVQ----CVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDEN 1657
C++ ++ + ++++ +A GQE++DK+C+ LGI+ E+EYFG Q+ G E LWLN RN++S+QVP PY F+VKY+V PH IL ++TR+QFY + G W+ + E ++IALM +FG Y++ ++ KYA FWP + E+ I+ + H +L +T +YELLR+++ + YG FY++ D + + L G+GP+GL LC++ +I+++ + V V + RV+ L++DDGS + + + + + + SL+R +TE FF+CD+V +L +D K + F + + Y +D+ T +EVYD ARR + S SP N A V+ + SS D E +V + E+++E ++ C +C D I+RVF PC HI+CC CA R+ +C ICR I++ H + W +DE+
Sbjct: 37 CYITQADNNVFHVEVEHKADGQEVIDKICKMLGIMDEAEYFGVQFMGLKNEMLWLNNRNRLSKQVPGSSPYHLYFRVKYYVPPHAILLEDTRNQFYNNVVQQLKGGVWDAESTLETQANLIALMAYTQFGPYNANTTPCKYACFWPDC-RGEIPPEAIRMAANFHRDLDGFTVSHAKYELLRIVSMEFPSYGTHFYEVKDIFDRKLLLGVGPEGLALCSSHSSVIERFPYCRVHTVTTSARVVTLNLLEDDGSVKGRNYQLATNRLASSLYRSITEIHAFFRCDSVRDTVLWQTTRDLKDALVSIFDHNG--KDYAFDVRYTFREVYDRARRHLYHCTSNTSPRGSPPNHAGIVLNNDESIASSSGGDALQRSSGDNASTAGGLKREYSSRAESIVSTEEVQEIVQERLREVGICRLCMDAPISRVFFPCGHIICCATCADRVEECSICRKPIELRHPCFLPWSADED 501
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Match: mylipb (E3 ubiquitin-protein ligase MYLIP-B-like [Source:NCBI gene;Acc:103029934]) HSP 1 Score: 228.794 bits (582), Expect = 3.303e-67 Identity = 141/428 (32.94%), Postives = 237/428 (55.37%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C + P+ ++++D D +A G++ L+KVCQ+LGII E +YFG Q+ G E LWLN+RN+IS+QV + P R +VK+FV+PH IL ++TRH F + K + G + + ++++ + AL+ QAEFG+Y+ +T +Y F+ +I E + I ++ + H L+ +Q EY+ L+L++ S YGV ++ D + + G+GP+GL +C F I ++++ A+ + + + + +DDG F + A+ L+R +TE F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR +S + + A DE V R++L+ L+E + CV+C D +I+ PC H++CC+ CA +L CP+CR ++ H Y
Sbjct: 27 CLITRPDGVVMEVDADPKANGEDCLNKVCQRLGII-EVDYFGLQFTGTKGESLWLNLRNRISQQVDSMSPCRLKLRVKFFVEPHLILQEQTRHLFLMHVKEELVRGSLS--LDSDQVVELCALLGQAEFGDYN--QNTAEY--FYTQIYGVEPATDIINRVTERHRELEGLSQASAEYQALQLVS-SLENYGVEWHWARDTEGQRVAIGVGPEGLLICKEDFTPITRFIYPAIQMATQSGKNVYVTITKDDGDNLVLLFKFITTSAASGLYRAITEIHAFYRCDTVTSAVMMQYSRDFKGHLASLFLNENIDLGKKYSFDIQRTSKEVYDRARRALFSAGLKKDAQQPGLSPCSR----THAGDEEEV-CRQKLQRLQEALTCVLCCDAEIDCALCPCGHVICCQNCANQLQHCPMCRLEVNRIQHVY 441
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Match: mylipa (myosin regulatory light chain interacting protein [Source:NCBI gene;Acc:103027301]) HSP 1 Score: 216.853 bits (551), Expect = 1.078e-62 Identity = 140/464 (30.17%), Postives = 246/464 (53.02%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKSNT--CRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQ-------CVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY-PKWISDENANASNRLCPLPEDQALIADT 1717
C V P+ ++++++D++A G++ L+KVC++LGII E +YFG Q+ G E LWLN+RN+IS+Q+ + P R +VK+FV+PH IL ++TRH F++ K + G G +E+ + AL+ QAEFG+Y+ +T KY ++ ++ +E + I H L+ +Q +EY+ L+L++ S YGV ++ D + L GIGP+G+ +C F L+++ + + + + + + ++ + F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ + + S + + ++ L+E +Q C++C + +I+ F PC H+VCC+ CA +L CP+CR++++ H Y P S N + P P + + T
Sbjct: 3 CHVTRPDSVVMEVEVDAKANGEDCLNKVCRRLGII-EVDYFGLQFSGSKGENLWLNLRNRISQQMDNLTPCRLRLRVKFFVEPHLILQEQTRHLFFMHVKEDLHRGHLRMG--SEQAEELSALLAQAEFGDYN--QNTAKY--WYTELCGKEPDQATVNSIIARHQALEGVSQGSVEYQALQLVS-SLEHYGVEWHWARDAEGQRLAIGIGPEGIAVCREDFSLVNRISYPIIQIATQSGKSVYLTVTKETSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENINLGKKYVFDIRRTSKEVYDYARRALYNAGIVDLMSRSGGRSPSSRSPSHGQQEVLDCSGCQQSRALQEKLQKLREALLCMLCCEEEIDAAFCPCGHMVCCQNCAKQLQSCPVCRSEVEHIQHVYLPTCTSLLNLTITGNGSPEPIHRGMATHT 458
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Match: PTPN14 (protein tyrosine phosphatase non-receptor type 14 [Source:NCBI gene;Acc:103023975]) HSP 1 Score: 72.7886 bits (177), Expect = 7.724e-13 Identity = 61/229 (26.64%), Postives = 110/229 (48.03%), Query Frame = 2
Query: 377 VNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQV------PLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSST---MKYALF---WPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGLFL 1021
+ L ++ +I+ + + GQE L+ V Q+L + E+ YFG + K Q P W+ + + +Q+ PL+ F V ++V + L E TR+Q+YLQ K + +G + S E+ + L QA+FG++ + S +Y LF WP + +E+ QK+ + H + + + E ELL + L +G + D ++ L G+ G+F+
Sbjct: 25 IRLLDNNVIECTLSVESTGQECLEAVAQRLEL-RETHYFGLWFHSKAQVPRWVELEKALKKQLDKFGNEPLLF-----FGVMFYVPNVSRLEQEVTRYQYYLQVKKEVLDGRLH--CSVEQGIRLAGLAVQADFGDFTQYPSQDFLREYVLFPVNWPHV--DEVLEDWTQKVAEEHKS--HYRMQPAEAELLYIKEAEKLDGFGQESFAAKDNYTNDLFIGVSFIGVFV 241
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Match: epb41l3b (erythrocyte membrane protein band 4.1-like 3b [Source:ZFIN;Acc:ZDB-GENE-021106-1]) HSP 1 Score: 72.7886 bits (177), Expect = 9.366e-13 Identity = 62/225 (27.56%), Postives = 104/225 (46.22%), Query Frame = 2
Query: 431 GQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY------HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVN 1081
GQ L DKVC L ++ E +YFG YR + WL+ ++ +Q+ P+ F F VK++ P + D TR+ LQ ++ + G +T L + + + Q+E G+Y + S +++A K L+E K+ D H N K T E E+L L N L MYGV + D + G+ GL + + I+++ + + K++
Sbjct: 101 GQVLFDKVCDHLNLL-EKDYFGLTYRDAENQKNWLDPAKELKKQI-RNGPWNFGFNVKFYPPDPAQLSEDITRYYLCLQLRDDVVSGRLPCSFATHSL--LGSYIAQSEVGDYDPEELGSDYVSDLRFAPNQTKELEE--------KVMDLHRNYKGMT--PAEAEMLFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRL-RINRFAWPKILKIS 310
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Match: ptpn3 (protein tyrosine phosphatase non-receptor type 3 [Source:NCBI gene;Acc:103022005]) HSP 1 Score: 71.2478 bits (173), Expect = 2.214e-12 Identity = 65/257 (25.29%), Postives = 113/257 (43.97%), Query Frame = 2
Query: 308 ISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQY-RGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQ-PHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY--HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL-----FLCTTKFGLID 1048
IS L + + T ++ C V P+ + + G L D+ C+ LGI+ E YF Q P WL+ +Q+ P+ F+V++F+ P+++ ++TRH ++LQ K I EG +S+ + A+ Q+EFG+Y + + + F P Q++ ++ + H L + E EL L L +YGV + D + SL GI G+ +C++ F I+
Sbjct: 12 ISSLGLPDLSKHTHMQRSSITCVVLFPDVTMHSFSVGKNDAGHLLFDQACEHLGIV-EKHYFSLQISEDSSSSPRWLDPNKPFKKQLKGTDPFYLIFRVRFFISDPNSLQHEQTRHFYFLQIKKDIREGRLKCPLSSGVVLASYAV--QSEFGDYVPETPAGYVDKIHFIPD--QDKDFLFKVESLHPQHKGLS-----QSEAELCYLNTARTLDLYGVELHSARDANNPSLWVGIASGGVAMFCNLVCSSFFPWIN 258
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000335.1 (pep scaffold:Pmarinus_7.0:GL476842:149708:151623:1 gene:ENSPMAG00000000302.1 transcript:ENSPMAT00000000335.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.6633 bits (226), Expect = 9.969e-23 Identity = 37/92 (40.22%), Postives = 64/92 (69.57%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETR 646
C V+ P+ ++++++D++A G++ +++VC+ L II E +YFG QY G E LW+N+RN++ Q+ P+R +VK+ V+PH +L DETR
Sbjct: 3 CLVSRPDSVVMEVELDAKAKGEDCVNEVCRHLRII-ERDYFGLQYEGTKGETLWINLRNRLGPQLSGAAPHRLRLRVKFLVEPHLLLQDETR 93
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 71.633 bits (174), Expect = 1.310e-13 Identity = 67/248 (27.02%), Postives = 111/248 (44.76%), Query Frame = 2
Query: 422 RAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGN----YHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+A+GQ+L D+V L I+ E +YFG Q+ Q WL+ I +QV + PY F +VK++ +P+ + + TR+ F LQ K I G E + QAE G+ H+ + ++ F P EE+ ++K +D Q + EL L WL MYGV + + G+ P G +F K GL + + +T+++ + V+++DD + Q
Sbjct: 2 KAVGQDLFDQVMYHLDIL-EVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLE--CPFETAVQLATYSLQAELGDCDPVEHNPALVSEFR-FIPS-QSEEMEEAILEKWKDCRG------QTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGL---FFWPKITRLDFKRTKLTLVVVEDDDQAKEQ 235
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 71.633 bits (174), Expect = 1.319e-13 Identity = 67/248 (27.02%), Postives = 111/248 (44.76%), Query Frame = 2
Query: 422 RAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGN----YHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+A+GQ+L D+V L I+ E +YFG Q+ Q WL+ I +QV + PY F +VK++ +P+ + + TR+ F LQ K I G E + QAE G+ H+ + ++ F P EE+ ++K +D Q + EL L WL MYGV + + G+ P G +F K GL + + +T+++ + V+++DD + Q
Sbjct: 2 KAVGQDLFDQVMYHLDIL-EVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLE--CPFETAVQLATYSLQAELGDCDPVEHNPALVSEFR-FIPS-QSEEMEEAILEKWKDCRG------QTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGL---FFWPKITRLDFKRTKLTLVVVEDDDQAKEQ 235
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450]) HSP 1 Score: 71.2478 bits (173), Expect = 1.668e-13 Identity = 67/248 (27.02%), Postives = 111/248 (44.76%), Query Frame = 2
Query: 422 RAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGN----YHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
+A+GQ+L D+V L I+ E +YFG Q+ Q WL+ I +QV + PY F +VK++ +P+ + + TR+ F LQ K I G E + QAE G+ H+ + ++ F P EE+ ++K +D Q + EL L WL MYGV + + G+ P G +F K GL + + +T+++ + V+++DD + Q
Sbjct: 2 KAVGQDLFDQVMYHLDIL-EVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLE--CPFETAVQLATYSLQAELGDCDPVEHNPALVSEFR-FIPS-QSEEMEEAILEKWKDCRG------QTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGL---FFWPKITRLDFKRTKLTLVVVEDDDQAKEQ 235
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001599.1 (pep scaffold:Pmarinus_7.0:GL478896:2253:11647:-1 gene:ENSPMAG00000001443.1 transcript:ENSPMAT00000001599.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 65.4698 bits (158), Expect = 2.796e-12 Identity = 46/146 (31.51%), Postives = 69/146 (47.26%), Query Frame = 2
Query: 362 TVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYA 796
TV C V+L + + D+D +A GQ L D VC+ L ++ E +YFG YR ++ WL+ +I RQV + F F K++ P + D TR+ LQ + + G T + AL QAE G++ YA
Sbjct: 25 TVPCSVSLLDGSVFPCDVDKQAKGQVLFDLVCEHLNLL-EKDYFGLNYRDNTEQKNWLDPNKEIKRQV-RAGAWTFIFNTKFYPPDPAQLTEDITRYYICLQLREDVASGRLPCSFVTHAVLGSYAL--QAELGDHEPDEHGPGYA 166
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Match: EDO41568 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3Y5]) HSP 1 Score: 199.134 bits (505), Expect = 4.511e-57 Identity = 137/436 (31.42%), Postives = 217/436 (49.77%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEEL--CHVIALMTQAEFGNYHSFSSTMKY-------ALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDI----LKDCK-TITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQ-ANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
CFV+LP+ + + D+ RA GQELLD VC++LGII E +YFG QY G E LWLN RN+I+RQV P R F+VK+FVQPH +L + +RHQ +L H+ + V T + + AL+ QA G++ + K+ + W L+ I H+ L EY L+ I E +G+ F+ + + L G+G + L + T+F I++ ++ + + + ++ DG +F + A+ L+R +TE F++C+TV + +D + T F + + + Y +D+ +T KEVYD R Y+ P N N+V + P + + ++++L L + ++C VC D +IN V IPC H+VCCE CA L CP+CR I A+
Sbjct: 3 CFVSLPDSTVSEFDLPERARGQELLDAVCKRLGII-EVDYFGLQYAGTKGETLWLNTRNRINRQVSGGPPLRLQFRVKFFVQPHLLLQEASRHQHFL----HLRKDFEGRKVVTNPVKSARMYALLAQATIGDHCNSHFVCKFCQNTENNSFEWTSDLR--------TNITQEHEKLNGVKPSTAEYHFLKEIAE-LEDFGIEFHTARNNIGQQLHIGVGSEELRIFDTEFNFIERISYNVLKMATHIAKSLFLTIMTTDGEDNVVEFKLITQGAACGLYRSITEYHAFYRCETVRNSVKSQFTRDFRETFFSLFNEEESDKKYIFDVKRTCKEVYD--YYRRVLYNQGCDPINGVTNNVREAEPPTHDLNASSDYSLQEKLSKLEDGLRCKVCMDEQINAVLIPCGHMVCCEQCAMNLEACPVCRGAIDHVQKAF 422
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Match: EDO42892 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S031]) HSP 1 Score: 72.0182 bits (175), Expect = 1.140e-13 Identity = 55/209 (26.32%), Postives = 93/209 (44.50%), Query Frame = 2
Query: 422 RAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTK 1033
++ GQEL+D V + L ++ E +YFG Q+ +Q WL+ KI +QV + PY F+VK++ +PH + + TR+ F+LQ K I V + A Q++ G+Y H ++ F KI + K+ K + E LR++ + YGV + + D + G+ P G+ + K
Sbjct: 2 KSKGQELIDLVMKNLDLV-EKDYFGLQFMDTHQVGHWLDPTKKIKKQVKIGPPYTLHFRVKFYAAEPHELGEELTRYHFFLQVKQDIARNKLE--VPQRTAVDLAAYSLQSQLGDYDAELHGDDYMAEFKFFLTKIENWKFKFARSTKLL-----CKGLNPAECEVNFLRIV-KGMDFYGVNLHSVVDQHKIEYELGLTPRGILVAREK 201
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Match: EDO34391 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPH7]) HSP 1 Score: 67.781 bits (164), Expect = 2.072e-12 Identity = 60/215 (27.91%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 377 VNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQV-PLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGL 1015
++L +D + + A GQ + D VC+ L ++ E +YFG +Y ++ WL++ + +Q+ L P++ F+VK++ + P I + TR+Q +LQ K I G S EL + A + QAE G+Y Y + +I+ ++ + KI D H +L E L + +S MYGV + D + L G+ P G+
Sbjct: 18 ISLLDDTELTCEFRRDAKGQTVFDTVCKALDLV-EKDYFGLRYVDDSKQRHWLDLSKSVIKQMKSLKPPFKLFFRVKFYALDPGLIHEEITRYQCFLQIKRDILHG--RLLCSYNELAELGAYIVQAELGDYDPEDQEDNYVSEF-RIVPKQSEKLE-NKIADIHRSLSGQVPSVAEKNFLDKV-KSLDMYGVDPHPCKDQDNVQLYLGLTPTGI 226
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Match: EDO33626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRN5]) HSP 1 Score: 69.707 bits (169), Expect = 2.474e-12 Identity = 63/233 (27.04%), Postives = 100/233 (42.92%), Query Frame = 2
Query: 389 NDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDE-TRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNC 1084
+D ++K DI+ + G L +V + L + E EYFG Y K WL+ I +QV I F F VK++ +L +E TR+ F LQ K + G ST L + + + Q E G++ + S Y + ++ + S +I D H + + +Y LL + MYGV Y D + L+ L G+I VF + +K+N
Sbjct: 31 DDSVVKFDIEPKVKGDILYKQVYEYLNL-DEREYFGLSYYDKSDNLFWLDQLKPIKKQVKEIGKVLFRFCVKFYTADPAMLQEEYTRYLFALQVKKDLVNGGLKCSESTAAL--LASYVVQGELGDFDTLSCRPGYLADFQFFPEQTVDSE--ARISDFHKQHRSLSPTDCDYNLLD-VARRLEMYGVILYPAKDKDNVDLE---------LAAANMGII---VFQSGSKINT 245
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Match: EDO48911 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHT5]) HSP 1 Score: 66.6254 bits (161), Expect = 5.261e-12 Identity = 57/212 (26.89%), Postives = 102/212 (48.11%), Query Frame = 2
Query: 377 VNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIIS-ESEYFGFQYRGKYQEPLWLNIRNKISRQVP----LILPYRFDFKVKYFV-QPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIA-LMTQAEFG-----NYHSFSS--TMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITD 970
V L +D + + + G + L+ + +KLG+ + YFG QYR K + WL++ +++Q+ + F+VKYFV +++ + R+ +YLQ K ++ G + E+ V+A + QAEFG N+H+++ + P Q EL Q+I++ H NL+ + E E +RL+ + YG +Y D
Sbjct: 23 VELLDDSSFDLILTDGSTGSDCLEIIAEKLGLTEVNTAYFGLQYRKK-GDDWWLDLAKPVAKQLSNHGRIAAVVTLKFRVKYFVCNAYSLQEEIARYLYYLQLKKNVLAGLL---LCDEQAAVVLASYIAQAEFGDADEENHHNYAKDFVLLPCTLVPVHTQNELS----QQIKELHTNLRGLSAHDAEMEFIRLVQQ-LEGYGDEYYPAKD 225
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Match: mylipa (myosin regulatory light chain interacting protein [Source:NCBI gene;Acc:101163590]) HSP 1 Score: 216.853 bits (551), Expect = 1.022e-62 Identity = 137/439 (31.21%), Postives = 241/439 (54.90%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKS--NTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVI-----------QKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C V P+ ++++ +D++A G++ L+KVC+KLGII E++YFG Q+ G E LWLN+RN+I +Q+ + P R +VK+FV+PH IL ++TRH F+L K + G G +E+ + AL+ QAEFG+Y+ +T +Y ++ ++ EE I I H L+ +Q +EY+ L+L++ S YGV ++ D + + G+GP+G+ +C F L+++ + + + + + + +D + F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ + + + + Q++ + S + +++ L+ LRE + C++C + +I+ F PC H+VCC+ CA +L CP+CR ++ H Y
Sbjct: 3 CHVTRPDSVVMEVQVDAKANGEDCLNKVCRKLGII-EADYFGLQFTGSKGENLWLNLRNRICQQMDNVTPCRLRLRVKFFVEPHLILQEQTRHLFFLHVKEDLHNGHLRMG--SEQAEELSALLAQAEFGDYN--QNTAQY--WYSELCGEEPSVATINSIISRHKALEGSSQASVEYQALQLVS-SMEHYGVEWHWARDANGQRMAIGVGPEGIAVCKDDFTLVNRISYPIIQIATQSGKSVYLTVTKDTSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENINVGKKYVFDIRRTAKEVYDHARRSLYNTGNRDLASRSKSSQHSPSSCSPTRDDQQDKDLDCGSCHMSRALQERLQKLREALLCMLCCEEEIDAAFCPCGHMVCCQTCANQLQLCPVCRADVEHVQHVY 433
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Match: mylipa (myosin regulatory light chain interacting protein [Source:NCBI gene;Acc:101163590]) HSP 1 Score: 211.46 bits (537), Expect = 9.457e-61 Identity = 136/439 (30.98%), Postives = 237/439 (53.99%), Query Frame = 2
Query: 371 CFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDIL----KDCKT-ITHFFRKS--NTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVI-----------QKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAY 1633
C V P+ ++++ +D++A G++ L+KVC+KLGII E++YFG Q+ G E LWLN+RN+I +Q+ + P R +VK+FV+PH IL ++TRH F+L K + G G +E+ + AL+ QAEFG+Y+ + A +W L E + R H L+ +Q +EY+ L+L++ S YGV ++ D + + G+GP+G+ +C F L+++ + + + + + + +D + F S +A+ L+R +TE+ F++CDTV ++ +D K + F N + Y +DI +T KEVYD ARR Y+ + + + + Q++ + S + +++ L+ LRE + C++C + +I+ F PC H+VCC+ CA +L CP+CR ++ H Y
Sbjct: 3 CHVTRPDSVVMEVQVDAKANGEDCLNKVCRKLGII-EADYFGLQFTGSKGENLWLNLRNRICQQMDNVTPCRLRLRVKFFVEPHLILQEQTRHLFFLHVKEDLHNGHLRMG--SEQAEELSALLAQAEFGDYNQNT-----AQYWYSELCGE------EPTRHRHKALEGSSQASVEYQALQLVS-SMEHYGVEWHWARDANGQRMAIGVGPEGIAVCKDDFTLVNRISYPIIQIATQSGKSVYLTVTKDTSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENINVGKKYVFDIRRTAKEVYDHARRSLYNTGNRDLASRSKSSQHSPSSCSPTRDDQQDKDLDCGSCHMSRALQERLQKLREALLCMLCCEEEIDAAFCPCGHMVCCQTCANQLQLCPVCRADVEHVQHVY 426
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:NCBI gene;Acc:111946734]) HSP 1 Score: 79.7221 bits (195), Expect = 4.233e-15 Identity = 67/275 (24.36%), Postives = 120/275 (43.64%), Query Frame = 2
Query: 356 TVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLK-----DW----TQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDG--LFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
T + C V+L + + +D+ +A G+EL +++ L I+ E +YFG ++ Q P WL++ I +QV + PY +VK++ +P+ + + TR+ F LQ K + G T + A QAE G+Y + ++ + I D + L+ W Q + E+ L WL MYGV + + G+ P G +F TK GL + + +T+++ + V+++DD + Q
Sbjct: 40 TSIITCRVSLLDGTDVSVDLPKKAKGEELFEQIMYHLDIV-EKDYFGLRFMDYAQVPHWLDVTKSIKKQVKIGPPYCLHMRVKFYSSEPNNLHEELTRYLFVLQLKQDVLSGKLECPFDT--AVELGAFSLQAELGDYDPLEHNLDLV-------------SEFRFIPDQTEELERAIYSAWKDCRGQTPAQAEINYLNKAKWLEMYGVDMHMVKARDGNEYSLGLTPTGVLVFEGQTKIGL---FFWPKITRLDFRKSKLTLVVVEDDEQGKEQ 295
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Match: epb41l4b (band 4.1-like protein 4B [Source:NCBI gene;Acc:101169231]) HSP 1 Score: 72.4034 bits (176), Expect = 6.781e-13 Identity = 74/285 (25.96%), Postives = 128/285 (44.91%), Query Frame = 2
Query: 326 SNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWN--HGVSTEELCHVIALMTQAEFGNYHSFSSTMKYA---LFWPKILQEELGSTDIQKIRDHHDNLKDWTQRK----IEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGL--FLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQ 1141
S + T ++ C V L + + + +D+ S+A GQEL D++ L +I E++YFG Q+ Q WL++ I +Q+ R F+VK++ +P+ + + TR+ F LQ + I G + VS E + A Q+E G+ T++ F PK Q E DI L W Q + + E+ L WL +YG+ + + G+ P G+ F + K GL + + +T+++ + V+++DD R Q
Sbjct: 55 SAHIQAAGTARSSITCRVLLLDGRDLVVDLPSKAKGQELFDQIMYYLDLI-ETDYFGLQFMDTDQVSHWLDLSKPIKKQIHDGQQNRLFFRVKFYSSEPNNLREEFTRYLFVLQLRQDILSGKLKCPYDVSVE----LAAYCLQSELGDCDPLEHTLELVSEFRFTPK--QSETMEADI---------LSRWLQLRGKSPSQAEIDFLNKCKWLELYGMDMHLVKGRDGGEYALGLTPTGILVFEDSNKIGL---FFWPKITRLDFKKSRLTLVVVEDDEQGREQ 320
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Match: epb41l3b (erythrocyte membrane protein band 4.1 like 3 [Source:NCBI gene;Acc:101175596]) HSP 1 Score: 69.707 bits (169), Expect = 6.616e-12 Identity = 63/247 (25.51%), Postives = 112/247 (45.34%), Query Frame = 2
Query: 365 VECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNY------HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWL-MYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVN 1081
++C V L + +D++ RA GQ L K+C+ L ++ E +YFG YR + WL+ ++ +Q+ P+ F F VK++ P + D TR+ LQ ++ + G +T + + + Q+E G+Y + S ++ A K L+E K+ + H K T E E+ L N L MYGV + D + G+ GL + K I+++ + + K++
Sbjct: 82 MQCKVALLDGSDYTVDVEKRAKGQILFSKICEHLNLL-EKDYFGITYRDIENQKNWLDPSKELKKQI-RNGPWNFAFNVKFYPPDPSQLSEDITRYYLCLQLRDDVVSGRLPCSFATHTV--LGSYTVQSELGDYDPEEMASDYVSELRLAPNQTKELEE--------KVMELHKTYKGMT--PAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDKL-RINRFAWPKILKIS 313
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Match: SMESG000007955.1 (SMESG000007955.1) HSP 1 Score: 965.681 bits (2495), Expect = 0.000e+0 Identity = 502/502 (100.00%), Postives = 502/502 (100.00%), Query Frame = 2
Query: 233 MHTMCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY 1738
MHTMCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQKFSTKSAKASKSLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDSARRRAYSYSSNNSPTNQANDVIQKNPESSQASDEVVVEMRKELEMLRELVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY
Sbjct: 1 MHTMCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQKFSTKSAKASKSLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDSARRRAYSYSSNNSPTNQANDVIQKNPESSQASDEVVVEMRKELEMLRELVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY 502
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Match: SMESG000007955.1 (SMESG000007955.1) HSP 1 Score: 958.748 bits (2477), Expect = 0.000e+0 Identity = 499/499 (100.00%), Postives = 499/499 (100.00%), Query Frame = 2
Query: 242 MCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQXXXXXXXXXXXXLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDXXXXXXXXXXXXXXPTNQANDVIQKNPESSQASDEVVVXXXXXXXXXXXXVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY 1738
MCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQKFSTKSAKASKSLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDSARRRAYSYSSNNSPTNQANDVIQKNPESSQASDEVVVEMRKELEMLRELVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY
Sbjct: 1 MCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNLPNDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQPHTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFLCTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQDDGSTRCQKFSTKSAKASKSLHRYVTESFQFFKCDTVDVDILKDCKTITHFFRKSNTCRSYFYDIVKTQKEVYDSARRRAYSYSSNNSPTNQANDVIQKNPESSQASDEVVVEMRKELEMLRELVQCVVCKDRKINRVFIPCMHIVCCEMCAARLNQCPICRNQIKISHHAYPKWISDENANASNRLCPLPEDQALIADTQGNETYY 499
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Match: SMESG000062741.1 (SMESG000062741.1) HSP 1 Score: 70.8626 bits (172), Expect = 1.898e-12 Identity = 58/211 (27.49%), Postives = 102/211 (48.34%), Query Frame = 2
Query: 389 NDQIIKIDIDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYF-VQP-HTILSDETRHQFYLQTKNHITEGCWNHGVSTEELCHVIALMTQAEFGNYHSFSSTMKYALFWPKILQEELGSTDIQKIRDHHDNLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGL 1015
N+ ++I + GQ LLD+VC++LG I E +YFG +Y K ++ W+++ + Q+ + F++K++ P + D + YLQ + + G + +L + A Q+E G+Y S S M+ +L K+L L S KI D H NL T ++E + L ++ YGV + + D +L G+ +G+
Sbjct: 22 NEPPLEIKVSHENSGQWLLDEVCERLGDIQEKDYFGLRYSDKDKQRQWIDLSRNVYNQLKDTPSFIVSFRMKHYPASPIEDLRQDRACYFLYLQLRKDLYSGRLLG--RSNDLYQLAAYAVQSEIGDYDSTSEDMR-SLSNLKLL-PNLNSKTEAKITDIHKNLCGLTPTEVEQKFLEKASQ-LDTYGVEPFYVKDQKGNNLYVGLTHEGV 227
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Match: SMESG000007133.1 (SMESG000007133.1) HSP 1 Score: 67.781 bits (164), Expect = 1.373e-11 Identity = 71/248 (28.63%), Postives = 114/248 (45.97%), Query Frame = 2
Query: 413 IDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQ-PHTILSDE-TRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHD-NLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFL--CTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
++ RA+GQ+L D ++ + + YFG QY K WL+I K+ +Q+ + P+ F+VK+F P + L DE TR+ F Q K + G C + ++ E + AL Q E G+Y HS + ++ F EEL I K D N+ T K E R + + YGV ++I K G+ P G+ + K GL + ++ VTK++ + V++QD
Sbjct: 49 LEKRALGQKLEDYTFHQIEVNDDKNYFGLQYTDKKNINHWLDIGKKVRKQLEIGPPFTLRFRVKFFSSDPCSQLHDEYTRYLFVQQLKLLLRSGELRCDDKDMAAE----IAALSLQGELGDYDEMEHSPAFISQFRFFPESQQTEELELLIISKFNLLKDRNILPSTADKQFLEKCRTLPD----YGVDQHNIKGKNDKDYILGLTPSGILIYEGQIKIGL---FPWNNVTKLSFKKSRFK-VVVQD 284
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Match: SMESG000007133.1 (SMESG000007133.1) HSP 1 Score: 67.781 bits (164), Expect = 1.480e-11 Identity = 71/248 (28.63%), Postives = 114/248 (45.97%), Query Frame = 2
Query: 413 IDSRAIGQELLDKVCQKLGIISESEYFGFQYRGKYQEPLWLNIRNKISRQVPLILPYRFDFKVKYFVQ-PHTILSDE-TRHQFYLQTKNHITEG---CWNHGVSTEELCHVIALMTQAEFGNY----HSFSSTMKYALFWPKILQEELGSTDIQKIRDHHD-NLKDWTQRKIEYELLRLINESWLMYGVTFYDITDCWSKSLKFGIGPDGLFL--CTTKFGLIDKWVFDAVTKVNCTDRVIEFVLIQD 1120
++ RA+GQ+L D ++ + + YFG QY K WL+I K+ +Q+ + P+ F+VK+F P + L DE TR+ F Q K + G C + ++ E + AL Q E G+Y HS + ++ F EEL I K D N+ T K E R + + YGV ++I K G+ P G+ + K GL + ++ VTK++ + V++QD
Sbjct: 49 LEKRALGQKLEDYTFHQIEVNDDKNYFGLQYTDKKNINHWLDIGKKVRKQLEIGPPFTLRFRVKFFSSDPCSQLHDEYTRYLFVQQLKLLLRSGELRCDDKDMAAE----IAALSLQGELGDYDEMEHSPAFISQFRFFPESQQTEELELLIISKFNLLKDRNILPSTADKQFLEKCRTLPD----YGVDQHNIKGKNDKDYILGLTPSGILIYEGQIKIGL---FPWNNVTKLSFKKSRFK-VVVQD 284 The following BLAST results are available for this feature:
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of E3 ubiquitin-protein ligase MYLIP vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001636 ID=SMED30001636|Name=E3 ubiquitin-protein ligase MYLIP|organism=Schmidtea mediterranea sexual|type=transcript|length=2008bpback to top protein sequence of SMED30001636-orf-1 >SMED30001636-orf-1 ID=SMED30001636-orf-1|Name=SMED30001636-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=503bp MHTMCERPNNLISFETPNHSPPHPLISDLPISNSFDSTRTPTVTVECFVNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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