cathepsin B

Overview
Namecathepsin B
Smed IDSMED30001635
Length (bp)1115
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cathepsin B (SMED30001635) t-SNE clustered cells

Violin plots show distribution of expression levels for cathepsin B (SMED30001635) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cathepsin B (SMED30001635) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cathepsin B (SMED30001635) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001635

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001635h1SMcG0017763 Contig42077newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001635h1SMcG0017763 Contig42077uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
intestinal phagocyteSMED30001635h1SMcG0017763 dd_Smed_v6_81_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30001635h1SMcG0017763 dd_Smed_v6_81_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001635h1SMcG0017763 dd_Smed_v6_81_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30001635h1SMcG0017763 dd_Smed_v4_81_0_1dd_Smed_v4PMID:30962434
Cote et al., 2019		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 387.882 bits (995), Expect = 4.376e-134
Identity = 188/315 (59.68%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       +S ++++ G  L  P   K P++      ++LPASFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+ AW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 387.882 bits (995), Expect = 4.376e-134
Identity = 188/315 (59.68%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       +S ++++ G  L  P   K P++      ++LPASFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+ AW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 387.882 bits (995), Expect = 4.376e-134
Identity = 188/315 (59.68%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       +S ++++ G  L  P   K P++      ++LPASFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+ AW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 387.882 bits (995), Expect = 4.376e-134
Identity = 188/315 (59.68%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       +S ++++ G  L  P   K P++      ++LPASFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+ AW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Human
Match: CTSB (cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527])

HSP 1 Score: 387.882 bits (995), Expect = 4.376e-134
Identity = 188/315 (59.68%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       +S ++++ G  L  P   K P++      ++LPASFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+ AW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-RNTTWQAGHNFYNVDMSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Celegans
Match: cpr-5 (Cathepsin B-like cysteine proteinase 5 [Source:UniProtKB/Swiss-Prot;Acc:P43509])

HSP 1 Score: 327.405 bits (838), Expect = 1.029e-110
Identity = 170/316 (53.80%), Postives = 206/316 (65.19%), Query Frame = 2 
Query:  146 LINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR----LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCG--FRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIG-PYPNCTGEF-PTPKCKKTCQA--GYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            LI+YVN  AQ  W AG       V    K+   L D   + +P K   + A      +P  FD+R QWP C SIN IRDQS+CGSCWAF A EA++DR CI SNG  N  +S+EDLL+CC   F CG+GC GG+P  AW +WV HGLVTGG Y    GC+ Y+   C   V G  +P C  +  PTPKC  +C +   YA  Y +DK FG T+Y+VG + E+I  EILTNGP+E AF+VY DF  Y +GVY H +GA LGGHA+KILGWGV+N TPYWLVANSWN  WG+KGYF+I +G NECGIE   VAGIP L
Sbjct:   32 LIDYVNS-AQKLWTAG-----HQVIPKEKITKKLMDVK-YLVPHKDEDIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDL 340
[Close]
BLAST of cathepsin B vs. Ensembl Celegans
Match: F57F5.1 (pep chromosome:WBcel235:V:12003028:12004600:1 gene:WBGene00010204.1 transcript:F57F5.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F57F5.1)

HSP 1 Score: 310.842 bits (795), Expect = 3.949e-104
Identity = 158/324 (48.77%), Postives = 218/324 (67.28%), Query Frame = 2 
Query:  113 PIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDI--RKVLG--VLKDPNNFKLPKKSS-GLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPY--PNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            P+        +L++YVN + QT++KA   + F +  D   ++++G  +++ P  +++ + +   +    +P SFDSR  WP C SI++IRDQS+CGSCWA  A E ++DR CI SN      ISA+D+  CCG  CG+GCNGG+P  AW  +V  G VTGG Y    GC+ Y +P C HHV G +  P  +  +PT KC+++CQAGYA TY++D  FG+++Y+V  +  EI +EI+T+GPVE AF+VY DF +Y  GVY H +GA LGGHA+K+LGWGV+N TPYWL ANSWN  WG+ GYF+I +G NECGIE  VV GIPKL
Sbjct:   29 PVEAQMLRGQELVDYVNKV-QTSFKAELGSYFSSYPDTIKKQLMGAKMVEIPEEYRVFEMTHPEVEDAAVPDSFDSRTAWPNCPSISKIRDQSSCGSCWAVSAAETISDRICIASNAKTILSISADDINACCGMVCGNGCNGGYPIEAWRHYVKKGYVTGGSYQDKTGCKPYPYPPCEHHVNGTHYKPCPSNMYPTDKCERSCQAGYALTYQQDLHFGQSAYAVSKKAAEIQKEIMTHGPVEVAFTVYEDFEHYSGGVYVHTAGASLGGHAVKMLGWGVDNGTPYWLCANSWNEDWGENGYFRIIRGVNECGIEGGVVGGIPKL 351
[Close]
BLAST of cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 306.605 bits (784), Expect = 3.750e-102
Identity = 162/320 (50.62%), Postives = 204/320 (63.75%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTV-SDIRKVLGVLKDPNNFKLP-------KKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHV----IGPYPNCTGEFPTPKCKKTCQAGYA-KTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            DLI+YVN   Q  W A    RF +V  +  K    L   N+ +L         K+  L+ + +P SFDSR  WPKC SI  IRDQS+CGSCWAFGAVEAM+DR CI S+G     +SA+DLL+CC   CG GCNGG P  AW +WV  G+VTG  Y A+ GC+ Y FP C HH       P P+    +PTPKC+K C + Y  KTY EDK FG ++Y V    E I +E++T+GP+E AF VY DF NY  GVY H  G + GGHA+K++GWG+++  PYW VANSWN  WG+ G+F+I +G +ECGIE  VV GIPKL
Sbjct:   35 DLIDYVNE-NQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLD-LDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPH--DLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 349
[Close]
BLAST of cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 306.99 bits (785), Expect = 3.846e-102
Identity = 162/320 (50.62%), Postives = 204/320 (63.75%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTV-SDIRKVLGVLKDPNNFKLP-------KKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHV----IGPYPNCTGEFPTPKCKKTCQAGYA-KTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            DLI+YVN   Q  W A    RF +V  +  K    L   N+ +L         K+  L+ + +P SFDSR  WPKC SI  IRDQS+CGSCWAFGAVEAM+DR CI S+G     +SA+DLL+CC   CG GCNGG P  AW +WV  G+VTG  Y A+ GC+ Y FP C HH       P P+    +PTPKC+K C + Y  KTY EDK FG ++Y V    E I +E++T+GP+E AF VY DF NY  GVY H  G + GGHA+K++GWG+++  PYW VANSWN  WG+ G+F+I +G +ECGIE  VV GIPKL
Sbjct:   44 DLIDYVNE-NQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLD-LDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPH--DLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 358
[Close]
BLAST of cathepsin B vs. Ensembl Celegans
Match: cpr-6 (Cathepsin B-like cysteine proteinase 6 [Source:UniProtKB/Swiss-Prot;Acc:P43510])

HSP 1 Score: 306.605 bits (784), Expect = 4.473e-102
Identity = 162/320 (50.62%), Postives = 204/320 (63.75%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTV-SDIRKVLGVLKDPNNFKLP-------KKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHV----IGPYPNCTGEFPTPKCKKTCQAGYA-KTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            DLI+YVN   Q  W A    RF +V  +  K    L   N+ +L         K+  L+ + +P SFDSR  WPKC SI  IRDQS+CGSCWAFGAVEAM+DR CI S+G     +SA+DLL+CC   CG GCNGG P  AW +WV  G+VTG  Y A+ GC+ Y FP C HH       P P+    +PTPKC+K C + Y  KTY EDK FG ++Y V    E I +E++T+GP+E AF VY DF NY  GVY H  G + GGHA+K++GWG+++  PYW VANSWN  WG+ G+F+I +G +ECGIE  VV GIPKL
Sbjct:   45 DLIDYVNE-NQNLWTAKKQRRFSSVYGENDKAKWGLMGVNHVRLSVKGKQHLSKTKDLD-LDIPESFDSRDNWPKCDSIKVIRDQSSCGSCWAFGAVEAMSDRICIASHGELQVTLSADDLLSCCK-SCGFGCNGGDPLAAWRYWVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPH--DLYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGGKLGGGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKL 359
[Close]
BLAST of cathepsin B vs. Ensembl Fly
Match: CtsB1 (gene:FBgn0030521 transcript:FBtr0346091)

HSP 1 Score: 330.872 bits (847), Expect = 4.767e-112
Identity = 168/319 (52.66%), Postives = 200/319 (62.70%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRFQ-TVSDIRKVLGVLKDPNNFKLPKKSSGLNAI------RLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGV--ENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            LS + I  V   A+T W  G       T   IR+++GV  D + F LP K   L  +       LP  FDSR QWP C +I EIRDQ +CGSCWAFGAVEAM+DR CIHS G  N   SA+DL++CC   CG GCNGGFP  AWS+W   G+V+GG YG++ GC+ Y    C HHV G  P C     TPKC   CQ+GY   Y +DK FG  SYSV     EI +EI+TNGPVE AF+VY D   YK GVYQH  G  LGGHAI+ILGWGV  E   PYWL+ NSWN  WGD G+F+I +G + CGIE  + AG+PKL
Sbjct:   24 LSDEFIEVVRSKAKT-WTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCC-HTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISAGLPKL 340
[Close]
BLAST of cathepsin B vs. Ensembl Fly
Match: CtsB1 (gene:FBgn0030521 transcript:FBtr0073838)

HSP 1 Score: 330.872 bits (847), Expect = 4.767e-112
Identity = 168/319 (52.66%), Postives = 200/319 (62.70%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRFQ-TVSDIRKVLGVLKDPNNFKLPKKSSGLNAI------RLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGV--ENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            LS + I  V   A+T W  G       T   IR+++GV  D + F LP K   L  +       LP  FDSR QWP C +I EIRDQ +CGSCWAFGAVEAM+DR CIHS G  N   SA+DL++CC   CG GCNGGFP  AWS+W   G+V+GG YG++ GC+ Y    C HHV G  P C     TPKC   CQ+GY   Y +DK FG  SYSV     EI +EI+TNGPVE AF+VY D   YK GVYQH  G  LGGHAI+ILGWGV  E   PYWL+ NSWN  WGD G+F+I +G + CGIE  + AG+PKL
Sbjct:   24 LSDEFIEVVRSKAKT-WTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCC-HTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISAGLPKL 340
[Close]
BLAST of cathepsin B vs. Ensembl Fly
Match: Swim (gene:FBgn0034709 transcript:FBtr0071785)

HSP 1 Score: 140.969 bits (354), Expect = 1.152e-37
Identity = 96/311 (30.87%), Postives = 152/311 (48.87%), Query Frame = 2 
Query:  146 LINYVNYIAQTTWKAGPTTRF--QTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR-LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSG---AMLGGHAIKILGWGVENN-TPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            +++ VN I +  W A    ++  +  S+  K+    K+P  +++   +   N    LP+SF++  +W     I+E+ DQ  CG+ W        +DR+ I S G +N ++SA+++L+C   R   GC GG    AW +    G+V            +  +P   H       + +       C+K         Y         +YS+  RE +IM EI  +GPV+A   V  DF  Y  GVY+  +    A  G H++K++GWG E+N   YW+ ANSW   WG+ GYF+I +G+NECGIE+ V+A  P
Sbjct:  132 IVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPT-YRVKAMTRLKNPTDGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSC--TRRQQGCEGGHLDAAWRYLHKKGVV-----------DENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTV-----GPAYSLN-READIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWP 420
[Close]
BLAST of cathepsin B vs. Ensembl Fly
Match: Swim (gene:FBgn0034709 transcript:FBtr0071784)

HSP 1 Score: 140.969 bits (354), Expect = 1.152e-37
Identity = 96/311 (30.87%), Postives = 152/311 (48.87%), Query Frame = 2 
Query:  146 LINYVNYIAQTTWKAGPTTRF--QTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR-LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSG---AMLGGHAIKILGWGVENN-TPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            +++ VN I +  W A    ++  +  S+  K+    K+P  +++   +   N    LP+SF++  +W     I+E+ DQ  CG+ W        +DR+ I S G +N ++SA+++L+C   R   GC GG    AW +    G+V            +  +P   H       + +       C+K         Y         +YS+  RE +IM EI  +GPV+A   V  DF  Y  GVY+  +    A  G H++K++GWG E+N   YW+ ANSW   WG+ GYF+I +G+NECGIE+ V+A  P
Sbjct:  132 IVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPT-YRVKAMTRLKNPTDGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSC--TRRQQGCEGGHLDAAWRYLHKKGVV-----------DENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTV-----GPAYSLN-READIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWP 420
[Close]
BLAST of cathepsin B vs. Ensembl Fly
Match: CG4847 (gene:FBgn0034229 transcript:FBtr0086935)

HSP 1 Score: 92.8189 bits (229), Expect = 1.567e-20
Identity = 78/283 (27.56%), Postives = 124/283 (43.82%), Query Frame = 2 
Query:  224 IRKVLGVLKDPNNFKLPKKSSGLNAIRLPAS-FDSRIQWPKCKSINEIRDQSNCGSCWAF---GAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFR--CGDGCNGGFPSGAWSFW--VSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTG--EFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVS-GAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDE 1039
            + ++ G+ + P      + ++ L  + LPA        W +   +  ++ Q  CGSCWAF   GA+E  T R      G+  P +S ++L+ C        +GC+GGF   A+ F   V  G+   G Y                    PY +  G  ++   K   T Q G+A    +D             EE++ + + T GPV  + +      NY  G+Y           H+I ++G+G E    YW+V NSW+ TWG+KGYF++ +G N C I +E
Sbjct:  173 LSQLTGLKRSPE--AKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFR----KTGSL-PNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAY--------------------PYIDNKGTCKYDGSKSGATLQ-GFAAIPPKD-------------EEQLKKVVATLGPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEE 414
[Close]
BLAST of cathepsin B vs. Ensembl Zebrafish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 358.992 bits (920), Expect = 4.658e-123
Identity = 179/321 (55.76%), Postives = 219/321 (68.22%), Query Frame = 2 
Query:  101 SVKGPIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            SV    P   PLS +++N++N  A TTW AG   R    S ++K+ G  LK P   KLP        ++LP +FD+R QWP C ++ EIRDQ +CGSCWAFGA EA++DR CIHS+   +  IS++DLLTCC   CG GCNGG+PS AW FW + GLVTGG Y +H+GC+ Y    C HHV G  P C+GE   TP C   C+ GY+ +YK+DK FGKTSYSV   +  IM E+  NGPVE AF+VY DF  YKSGVYQH+SG+ +GGHAIKILGWG EN  PYWL ANSWN  WGD GYFKI +G + CGIE E+VAGIP
Sbjct:   14 SVSWARPRLPPLSHEMVNFINK-ANTTWTAGHNFRDVDYSYVKKLCGTFLKGP---KLPVMVQYTEGLKLPKNFDAREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSDAKVSVEISSQDLLTCCD-SCGMGCNGGYPSAAWDFWATEGLVTGGLYNSHIGCRPYTIEPCEHHVNGSRPPCSGEGGDTPNCDMKCEPGYSPSYKQDKHFGKTSYSVPSNQNSIMAELFKNGPVEGAFTVYEDFLLYKSGVYQHMSGSPVGGHAIKILGWGEENGVPYWLAANSWNTDWGDNGYFKILRGEDHCGIESEIVAGIP 329
[Close]
BLAST of cathepsin B vs. Ensembl Zebrafish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 355.91 bits (912), Expect = 7.902e-122
Identity = 172/308 (55.84%), Postives = 221/308 (71.75%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            ++I+++N  A++TW AG          ++ + G VLK P   +LP        ++LP SFD R QWP CK++N+IRDQ +CGSCWAFGAVE+++DR CIHS G ++P ISAEDLL+CC  +CG GC+GGFP+ AW +W   GLVTGG Y + +GC+ Y+   C HHV G  P C+GE  TPKC   C   Y+  YK+DK FG   Y+V   +++IM E+ TNGPVEAAF+VY DFP YKSGVYQH++G+ LGGHA+KILGWG EN TP+WLVANSWN  WGD GYFKI +G +ECGIE E+VAG+PKL
Sbjct:   24 EMISFIN-AARSTWTAGVNFDNVPKKYLKSLCGTVLKGP---RLPHTVKHSTNVKLPDSFDLRDQWPNCKTLNQIRDQGSCGSCWAFGAVESISDRICIHSKGKQSPEISAEDLLSCCD-QCGFGCSGGFPAEAWDYWRRSGLVTGGLYNSDVGCRPYSIAPCEHHVNGTRPPCSGEQDTPKCTGVCIPKYSVPYKQDKHFGSKVYNVPSDQQQIMTELYTNGPVEAAFTVYEDFPLYKSGVYQHLTGSALGGHAVKILGWGEENGTPFWLVANSWNSDWGDNGYFKILRGHDECGIESEMVAGLPKL 326
[Close]
BLAST of cathepsin B vs. Ensembl Zebrafish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 288.115 bits (736), Expect = 6.910e-96
Identity = 147/275 (53.45%), Postives = 184/275 (66.91%), Query Frame = 2 
Query:  101 SVKGPIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILG 919
            SV    P   PLS +++N++N  A TTW AG   R    S ++K+ G  LK P   KLP        ++LP +FD+R QWP C ++ EIRDQ +CGSCWAFGA EA++DR CIHS+   +  IS++DLLTCC   CG GCNGG+PS AW FW + GLVTGG Y +H+GC+ Y    C HHV G  P C+GE   TP C   C+ GY+ +YK+DK FGKTSYSV   +  IM E+  NGPVE AF+VY DF  YKSGVYQH+SG+ +GGHAIKILG
Sbjct:   14 SVSWARPRLPPLSHEMVNFINK-ANTTWTAGHNFRDVDYSYVKKLCGTFLKGP---KLPVMVQYTEGLKLPKNFDAREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSDAKVSVEISSQDLLTCCD-SCGMGCNGGYPSAAWDFWATEGLVTGGLYNSHIGCRPYTIEPCEHHVNGSRPPCSGEGGDTPNCDMKCEPGYSPSYKQDKHFGKTSYSVPSNQNSIMAELFKNGPVEGAFTVYEDFLLYKSGVYQHMSGSPVGGHAIKILG 283
[Close]
BLAST of cathepsin B vs. Ensembl Zebrafish
Match: tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:ZFIN;Acc:ZDB-GENE-060503-240])

HSP 1 Score: 142.895 bits (359), Expect = 6.304e-38
Identity = 88/260 (33.85%), Postives = 127/260 (48.85%), Query Frame = 2 
Query:  305 LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSG--------AMLGGHAIKILGWGVENN-----TPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVV 1045
            LP+ F++  +WP    I+E  DQ NC + WAF      +DR  I S G   P++S ++L++C   R  DGC GG   GAW F    G+VT         C  ++ P+ S   +      +      K + T     + +Y  D       Y +   E EIM+EI+ NGPV+A   V+ DF  YKSG+++H                H+++I GWG E +       YW+ ANSW   WG+ GYF+I +G NEC IE  V+
Sbjct:  200 LPSYFNAVDKWPG--KIHEPLDQGNCNASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISC-DTRHQDGCAGGRIDGAWWFMRRRGVVT-------QDCYPFSPPEQSAVEVARCMMQSRAVGRGKRQATAHCPNSHSYHNDIYQSTPPYRLSTNENEIMKEIMDNGPVQAIMEVHEDFFVYKSGIFRHTDVNYHKPSQYRKHATHSVRITGWGEERDYSGRTRKYWIGANSWGKNWGEDGYFRIARGVNECDIETFVI 449
[Close]
BLAST of cathepsin B vs. Ensembl Zebrafish
Match: ctsc (cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9])

HSP 1 Score: 123.25 bits (308), Expect = 6.094e-31
Identity = 98/348 (28.16%), Postives = 152/348 (43.68%), Query Frame = 2 
Query:   71 DRTKWESLTKSVKGPIPIHTPLSF-DLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAI---RLPASFDSRIQWPKCKSIN---EIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHV------SGAMLGGHAIKILGWGVENNT--PYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAG--IPKL 1063
            DR         +   +P    + F D IN V    Q +W A   +  +T+S I ++L     P + ++P++   +      +  A       W     +N    +R+Q+ CGSC++F  +  +  R  I +N T+ P  S + +++C  +    GC+GGFP     +    G+V           ++  FP             TG          C   YA  Y     F       G  E  +M E++ NGP+  A  VY DF NYK G+Y H       +   L  HA+ ++G+G  + T   YW+V NSW   WG+ G+F+I++GT+EC IE   VA   IPKL
Sbjct:  144 DRRHMLGFEHRLLMKLPYTNNMMFVDEINSV----QKSWTATVYSFHETLS-IHEMLRRSGGPAS-RIPRRVRPVTVAADSKAAAGLPQHWDWRNVNGVNFVSPVRNQAQCGSCYSFATMGMLEARVRIQTNNTQQPVFSPQQVVSCSQY--SQGCDGGFPYLIGKYIQDFGIV-----------EEDCFPY------------TGSDSPCNLPAKCTKYYASDYHYVGGFYG-----GCSESAMMLELVKNGPMGVALEVYPDFMNYKEGIYHHTGLRDANNPFELTNHAVLLVGYGQCHKTGEKYWIVKNSWGSGWGENGFFRIRRGTDECAIESIAVAATPIPKL 455
[Close]
BLAST of cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 385.571 bits (989), Expect = 2.227e-133
Identity = 187/316 (59.18%), Postives = 222/316 (70.25%), Query Frame = 2 
Query:  116 IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            +P   PLS D++NY+N +  TTWKAG       +  ++++ G     N  +L K+    + + LP SFDSR  WP C +I E+RDQ +CGSCWAFGAVEA++DR C+H+NG  N  +SAEDLL+CCGF CG GCNGG+PSGAW FW   GLV+GG Y +HLGC+ Y+ P C HHV G  P C GE   TPKC K C+ GYA  Y  DK FG TSY V   E+EIM EI  NGPVE AF VYADFP YKSGVYQH +G  LGGHAIKILGWGVEN TPYWL ANSWN  WGD G+FKI +G + CGIE E+VAGIPK
Sbjct:   20 LPFFAPLSGDMVNYINKM-NTTWKAGHNFANADLHYVKRLCGT--HLNGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGIESEIVAGIPK 332
[Close]
BLAST of cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 370.548 bits (950), Expect = 1.082e-126
Identity = 179/307 (58.31%), Postives = 214/307 (69.71%), Query Frame = 2 
Query:  116 IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIE 1033
            +P   PLS D++NY+N +  TTWKAG       +  ++++ G     N  +L K+    + + LP SFDSR  WP C +I E+RDQ +CGSCWAFGAVEA++DR C+H+NG  N  +SAEDLL+CCGF CG GCNGG+PSGAW FW   GLV+GG Y +HLGC+ Y+ P C HHV G  P C GE   TPKC K C+ GYA  Y  DK FG TSY V   E+EIM EI  NGPVE AF VYADFP YKSGVYQH +G  LGGHAIKILGWGVEN TPYWL ANSWN  WGD G+FKI +G + CGI+
Sbjct:   20 LPFFAPLSGDMVNYINKM-NTTWKAGHNFANADLHYVKRLCGT--HLNGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGID 323
[Close]
BLAST of cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 362.459 bits (929), Expect = 1.993e-124
Identity = 172/269 (63.94%), Postives = 197/269 (73.23%), Query Frame = 2 
Query:  257 NNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            N  +L K+    + + LP SFDSR  WP C +I E+RDQ +CGSCWAFGAVEA++DR C+H+NG  N  +SAEDLL+CCGF CG GCNGG+PSGAW FW   GLV+GG Y +HLGC+ Y+ P C HHV G  P C GE   TPKC K C+ GYA  Y  DK FG TSY V   E+EIM EI  NGPVE AF VYADFP YKSGVYQH +G  LGGHAIKILGWGVEN TPYWL ANSWN  WGD G+FKI +G + CGIE E+VAGIPK
Sbjct:   50 NGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNGFFKILRGKDHCGIESEIVAGIPK 318
[Close]
BLAST of cathepsin B vs. Ensembl Xenopus
Match: ctsb (cathepsin B [Source:NCBI gene;Acc:394833])

HSP 1 Score: 352.443 bits (903), Expect = 5.565e-120
Identity = 172/293 (58.70%), Postives = 203/293 (69.28%), Query Frame = 2 
Query:  116 IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKG 991
            +P   PLS D++NY+N +  TTWKAG       +  ++++ G     N  +L K+    + + LP SFDSR  WP C +I E+RDQ +CGSCWAFGAVEA++DR C+H+NG  N  +SAEDLL+CCGF CG GCNGG+PSGAW FW   GLV+GG Y +HLGC+ Y+ P C HHV G  P C GE   TPKC K C+ GYA  Y  DK FG TSY V   E+EIM EI  NGPVE AF VYADFP YKSGVYQH +G  LGGHAIKILGWGVEN TPYWL ANSWN  WGD G
Sbjct:   44 LPFFAPLSGDMVNYINKM-NTTWKAGHNFANADLHYVKRLCGT--HLNGPQLQKRFGFADGMELPDSFDSRAAWPNCPTIREVRDQGSCGSCWAFGAVEAISDRVCVHTNGKVNVEVSAEDLLSCCGFECGMGCNGGYPSGAWKFWTETGLVSGGLYDSHLGCRPYSIPPCEHHVNGSRPACKGEEGDTPKCVKQCEDGYAPVYGSDKHFGATSYGVPSSEKEIMAEIYKNGPVEGAFLVYADFPMYKSGVYQHETGEELGGHAIKILGWGVENGTPYWLCANSWNTDWGDNG 333
[Close]
BLAST of cathepsin B vs. Ensembl Xenopus
Match: TINAGL1 (tubulointerstitial nephritis antigen-like 1 [Source:NCBI gene;Acc:100124858])

HSP 1 Score: 136.346 bits (342), Expect = 7.701e-36
Identity = 97/311 (31.19%), Postives = 146/311 (46.95%), Query Frame = 2 
Query:  182 WKAGPTTRF--QTVSD-IRKVLGVLKDPNN-FKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPT-----PKCKKTCQAGYAKTYKEDKQFGKT-SYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHV--------SGAMLGGHAIKILGWGVE-----NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVV 1045
            W AG  ++F   T+ + I+  LG  K  ++   + +    +N   LP+ F++  +WP    ++E  DQ NC   WAF      +DR  I S G     +S ++LL+C   R   GC GG   GAW +    G+V+           +  +P  S +  G    C  +  +      +    C   Y   Y  ++ +  T +Y +   E++IM+E+  NGPV+A   V+ DF  YKSG+Y+H              G H++KI GWG E         YWL ANSW   WG+ GYF+I +G NEC IE  +V
Sbjct:  110 WTAGNYSQFWGMTLDEGIQYRLGTAKPSSSVMNMNEIHVNMNNDILPSHFNAAEKWPGL--VHEPLDQGNCAGSWAFSTAAVASDRISIQSMGHMTQSLSPQNLLSC-DTRNQHGCRGGRVDGAWWYLRRRGVVS-----------EPCYPFTSLNTNGHSAPCMMQSRSMGRGKRQATNNCPNQY---YSSNEIYQSTPAYRLASSEKDIMKELYENGPVQAIMEVHEDFFMYKSGIYRHTPVTEREPEHHRRHGTHSVKITGWGEERGRDGQTHKYWLAANSWGRDWGEDGYFRIARGENECEIETFIV 403
[Close]
BLAST of cathepsin B vs. Ensembl Mouse
Match: Ctsb (cathepsin B [Source:MGI Symbol;Acc:MGI:88561])

HSP 1 Score: 390.963 bits (1003), Expect = 1.665e-135
Identity = 190/315 (60.32%), Postives = 229/315 (72.70%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS DLINY+N    TTW+AG       +S ++K+ G VL  P   KLP + +    I LP +FD+R QW  C +I +IRDQ +CGSCWAFGAVEA++DR CIH+NG  N  +SAEDLLTCCG +CGDGCNGG+PSGAWSFW   GLV+GG Y +H+GC  Y  P C HHV G  P CTGE  TP+C K+C+AGY+ +YKEDK FG TSYSV    +EIM EI  NGPVE AF+V++DF  YKSGVY+H +G M+GGHAI+ILGWGVEN  PYWL ANSWN  WGD G+FKI +G N CGIE E+VAGIP+
Sbjct:   21 PSFHPLSDDLINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGP---KLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIPR 331
[Close]
BLAST of cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 145.206 bits (365), Expect = 7.446e-39
Identity = 103/324 (31.79%), Postives = 149/324 (45.99%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTVS---DIRKVLGVLKDPN---NFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNC---TGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAM--------LGGHAIKILGWGVE-----NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVA 1048
            D+I  +N      W+AG  + F  ++    IR  LG ++  +   N        G   + LP +F++  +WP    I+E  DQ NC   WAF      +DR  IHS G   P +S ++LL+C       GC GG   GAW F    G+V+            Y F     +   P P C   +      K + T +    +    D      +Y +G  E+EIM+E++ NGPV+A   V+ DF  Y+ G+Y H   +          G H++KI GWG E         YW  ANSW P WG++G+F+I +GTNEC IE  V+ 
Sbjct:  144 DMIKAINR-GNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEV-LPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSD---------NCYPFSGREQNEASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 145.206 bits (365), Expect = 7.446e-39
Identity = 103/324 (31.79%), Postives = 149/324 (45.99%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTVS---DIRKVLGVLKDPN---NFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNC---TGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAM--------LGGHAIKILGWGVE-----NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVA 1048
            D+I  +N      W+AG  + F  ++    IR  LG ++  +   N        G   + LP +F++  +WP    I+E  DQ NC   WAF      +DR  IHS G   P +S ++LL+C       GC GG   GAW F    G+V+            Y F     +   P P C   +      K + T +    +    D      +Y +G  E+EIM+E++ NGPV+A   V+ DF  Y+ G+Y H   +          G H++KI GWG E         YW  ANSW P WG++G+F+I +GTNEC IE  V+ 
Sbjct:  144 DMIKAINR-GNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEV-LPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSD---------NCYPFSGREQNEASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 145.206 bits (365), Expect = 7.446e-39
Identity = 103/324 (31.79%), Postives = 149/324 (45.99%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTVS---DIRKVLGVLKDPN---NFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNC---TGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAM--------LGGHAIKILGWGVE-----NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVA 1048
            D+I  +N      W+AG  + F  ++    IR  LG ++  +   N        G   + LP +F++  +WP    I+E  DQ NC   WAF      +DR  IHS G   P +S ++LL+C       GC GG   GAW F    G+V+            Y F     +   P P C   +      K + T +    +    D      +Y +G  E+EIM+E++ NGPV+A   V+ DF  Y+ G+Y H   +          G H++KI GWG E         YW  ANSW P WG++G+F+I +GTNEC IE  V+ 
Sbjct:  144 DMIKAINR-GNYGWQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEV-LPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSD---------NCYPFSGREQNEASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 453
[Close]
BLAST of cathepsin B vs. Ensembl Mouse
Match: Tinagl1 (tubulointerstitial nephritis antigen-like 1 [Source:MGI Symbol;Acc:MGI:2137617])

HSP 1 Score: 144.05 bits (362), Expect = 1.245e-38
Identity = 100/311 (32.15%), Postives = 144/311 (46.30%), Query Frame = 2 
Query:  182 WKAGPTTRFQTVS---DIRKVLGVLKDPN---NFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNC---TGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAM--------LGGHAIKILGWGVE-----NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVA 1048
            W+AG  + F  ++    IR  LG ++  +   N        G   + LP +F++  +WP    I+E  DQ NC   WAF      +DR  IHS G   P +S ++LL+C       GC GG   GAW F    G+V+            Y F     +   P P C   +      K + T +    +    D      +Y +G  E+EIM+E++ NGPV+A   V+ DF  Y+ G+Y H   +          G H++KI GWG E         YW  ANSW P WG++G+F+I +GTNEC IE  V+ 
Sbjct:  125 WQAGNHSAFWGMTLDEGIRYRLGTIRPSSTVMNMNEIYTVLGQGEV-LPTAFEASEKWPNL--IHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPILSPQNLLSCDTHH-QQGCRGGRLDGAWWFLRRRGVVSD---------NCYPFSGREQNEASPTPRCMMHSRAMGRGKRQATSRCPNGQVDSNDIYQVTPAYRLGSDEKEIMKELMENGPVQALMEVHEDFFLYQRGIYSHTPVSQGRPEQYRRHGTHSVKITGWGEETLPDGRTIKYWTAANSWGPWWGERGHFRIVRGTNECDIETFVLG 422
[Close]
BLAST of cathepsin B vs. UniProt/SwissProt
Match: sp|P83205|CATB_SHEEP (Cathepsin B OS=Ovis aries OX=9940 GN=CTSB PE=1 SV=2)

HSP 1 Score: 398.667 bits (1023), Expect = 1.152e-137
Identity = 192/310 (61.94%), Postives = 232/310 (74.84%), Query Frame = 2 
Query:  131 PLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            PLS +++NYVN    TTWKAG       +S ++K+ G +L  P   KLP++ +    + LP SFD+R QWP C +I EIRDQ +CGSCWAFGAVEA++DR CIHS G  N  +SAED+LTCCG  CGDGCNGGFPSGAW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ +YK+DK FG +SYSV   E+EIM EI  NGPVE AFSVY+DF  YKSGVYQHVSG M+GGHAI+ILGWGVEN+TPYWLV NSWN  WGDKG+FKI +G + CGIE E+VAG+P
Sbjct:   25 PLSDEMVNYVNK-QNTTWKAGHNFYNVDLSYVKKLCGAILGGP---KLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMP 330
[Close]
BLAST of cathepsin B vs. UniProt/SwissProt
Match: sp|P00787|CATB_RAT (Cathepsin B OS=Rattus norvegicus OX=10116 GN=Ctsb PE=1 SV=2)

HSP 1 Score: 395.201 bits (1014), Expect = 2.238e-136
Identity = 190/315 (60.32%), Postives = 230/315 (73.02%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS D+INY+N    TTW+AG       +S ++K+ G VL  PN   LP++      I LP SFD+R QW  C +I +IRDQ +CGSCWAFGAVEAM+DR CIH+NG  N  +SAEDLLTCCG +CGDGCNGG+PSGAW+FW   GLV+GG Y +H+GC  Y  P C HHV G  P CTGE  TPKC K C+AGY+ +YKEDK +G TSYSV   E+EIM EI  NGPVE AF+V++DF  YKSGVY+H +G ++GGHAI+ILGWG+EN  PYWLVANSWN  WGD G+FKI +G N CGIE E+VAGIP+
Sbjct:   21 PSSHPLSDDMINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGPN---LPERVGFSEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGSRPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGENHCGIESEIVAGIPR 331
[Close]
BLAST of cathepsin B vs. UniProt/SwissProt
Match: sp|P10605|CATB_MOUSE (Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 SV=2)

HSP 1 Score: 390.963 bits (1003), Expect = 1.165e-134
Identity = 190/315 (60.32%), Postives = 229/315 (72.70%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS DLINY+N    TTW+AG       +S ++K+ G VL  P   KLP + +    I LP +FD+R QW  C +I +IRDQ +CGSCWAFGAVEA++DR CIH+NG  N  +SAEDLLTCCG +CGDGCNGG+PSGAWSFW   GLV+GG Y +H+GC  Y  P C HHV G  P CTGE  TP+C K+C+AGY+ +YKEDK FG TSYSV    +EIM EI  NGPVE AF+V++DF  YKSGVY+H +G M+GGHAI+ILGWGVEN  PYWL ANSWN  WGD G+FKI +G N CGIE E+VAGIP+
Sbjct:   21 PSFHPLSDDLINYINK-QNTTWQAGRNFYNVDISYLKKLCGTVLGGP---KLPGRVAFGEDIDLPETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRCNKSCEAGYSPSYKEDKHFGYTSYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYKHEAGDMMGGHAIRILGWGVENGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGIPR 331
[Close]
BLAST of cathepsin B vs. UniProt/SwissProt
Match: sp|Q4R5M2|CATB_MACFA (Cathepsin B OS=Macaca fascicularis OX=9541 GN=CTSB PE=2 SV=1)

HSP 1 Score: 390.578 bits (1002), Expect = 1.946e-134
Identity = 189/315 (60.00%), Postives = 231/315 (73.33%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS +L+NYVN    TTW+AG       VS ++++ G  L  P   K P++      ++LP SFD+R QWP+C +I EIRDQ +CGSCWAFGAVEA++DR CIH+N   +  +SAEDLLTCCG  CGDGCNGG+P+GAW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY+ TYK+DK +G  SYSV   E++IM EI  NGPVE AFSVY+DF  YKSGVYQHV+G M+GGHAI+ILGWGVEN TPYWLVANSWN  WGD G+FKI +G + CGIE EVVAGIP+
Sbjct:   21 PSFHPLSDELVNYVNK-QNTTWQAGHNFYNVDVSYLKRLCGTFLGGP---KPPQRVMFTEDLKLPESFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGIMCGDGCNGGYPAGAWNFWTRKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPR 331
[Close]
BLAST of cathepsin B vs. UniProt/SwissProt
Match: sp|A1E295|CATB_PIG (Cathepsin B OS=Sus scrofa OX=9823 GN=CTSB PE=1 SV=1)

HSP 1 Score: 388.652 bits (997), Expect = 8.074e-134
Identity = 187/310 (60.32%), Postives = 228/310 (73.55%), Query Frame = 2 
Query:  131 PLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGV-LKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            PLS +L+N++N    TTW AG       +S ++K+ G  L  P   KLP++++    + LP SFD+R QWP C +I EIRDQ +CGSCWAFGAVEA++DR CI SNG  N  +SAED+LTCCG  CGDGCNGGFPSGAW+FW   GLV+GG Y +H+GC+ Y+ P C HHV G  P CTGE  TPKC K C+ GY  +YKEDK FG +SYS+   E+EIM EI  NGPVE AF+VY+DF  YKSGVYQHV+G ++GGHAI+ILGWGVEN TPYWLV NSWN  WGD G+FKI +G + CGIE E+VAGIP
Sbjct:   25 PLSDELVNFINK-QNTTWTAGHNFYNVDLSYVKKLCGTFLGGP---KLPQRAAFAADMILPKSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIRSNGRVNVEVSAEDMLTCCGDECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYTPSYKEDKHFGCSSYSISRNEKEIMAEIYKNGPVEGAFTVYSDFLQYKSGVYQHVTGDLMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGIP 330
[Close]
BLAST of cathepsin B vs. TrEMBL
Match: A0A1S3JJ47 (cathepsin B OS=Lingula unguis OX=7574 GN=LOC106173360 PE=3 SV=1)

HSP 1 Score: 432.565 bits (1111), Expect = 1.741e-148
Identity = 198/323 (61.30%), Postives = 249/323 (77.09%), Query Frame = 2 
Query:  116 IPIHTPLSFDLINYVNYIAQTTWKAGP--TTRFQTVSDIRKVLGVLKDPNNFKLPKKSS-----GLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            +P+H PLS +LI+YVN++A+ TWKAG     R  T  D++K+ GVL+DP     P +       G++A  +P  FDSR  WP C S+ EIRDQS CGSCWAFGAVEAMTDR CI S+G +N  ISAEDL+TCCGF CG+GCNGGFP GAWS+WV  G+V+GG+YG+H GC+ Y+ P C HHV G  P C G+ PTP+C+K C++GY+ +YKEDK +GK+ YSV   E+ I  EI+TNGPVE AF+VYADFP+YKSGVY H SG+ LGGHAIK+LGWGVE+ TPYWLVANSWNP WGD+G+FKIK+GT+ECGIE  +VAG+P++
Sbjct:   24 VPLHKPLSEELIHYVNHVAKATWKAGHNFVGRNMTEKDLKKLCGVLEDPMGKHRPTEIDPFEMYGMDANDIPEEFDSRTNWPNCPSLKEIRDQSACGSCWAFGAVEAMTDRICIASSGKQNVHISAEDLMTCCGFMCGNGCNGGFPGGAWSYWVRDGIVSGGQYGSHQGCRPYSLPSCEHHVNGSKPACKGDDPTPRCEKKCESGYSVSYKEDKNYGKSHYSVRSSEKSIQTEIMTNGPVEGAFTVYADFPSYKSGVYHHTSGSALGGHAIKVLGWGVESGTPYWLVANSWNPDWGDQGFFKIKRGTDECGIESGIVAGLPRV 346
[Close]
BLAST of cathepsin B vs. TrEMBL
Match: A0A1I8FYB7 (Pept_C1 domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 426.787 bits (1096), Expect = 2.468e-146
Identity = 196/315 (62.22%), Postives = 238/315 (75.56%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR-LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P+H PL+  LI+YVN   Q+TW A    RF+T++D+R +LGVL +PN   LP+ S   +A++ LP  FDSR QWP C +I EIRDQSNCGSCWAFGAVEAM+DR+CIHS G   P +SAEDLL+CCGF CG GCNGGFP GAW +W S GLVTGG+YG   GCQ Y+ P C HH  G Y  CTG+ PTPKC K C   Y  TY++DK FG ++YSV   E++IM EI+TNGPVE AF+VYADFP+YKSGVYQH +G  LGGHAI+ILGWG +  TPYWLVANSWN  WG++G+F+I +G +ECGIE  VVAG+PK
Sbjct:   24 PMHRPLTDSLIDYVNSQKQSTWTATRYNRFKTLADVRVLLGVLPNPNPSSLPELSYPESALKDLPEEFDSRKQWPNCPTIGEIRDQSNCGSCWAFGAVEAMSDRHCIHSGGKSKPHLSAEDLLSCCGFSCGMGCNGGFPEGAWHYWKSKGLVTGGQYGTKDGCQPYSLPHCEHHTTGEYQPCTGDSPTPKCTKQCIKEYNSTYQQDKHFGASAYSVRSNEQQIMTEIMTNGPVEGAFTVYADFPSYKSGVYQHTTGGSLGGHAIRILGWGADGGTPYWLVANSWNSDWGERGFFRILRGKDECGIESSVVAGLPK 338
[Close]
BLAST of cathepsin B vs. TrEMBL
Match: A0A1I8JK49 (Pept_C1 domain-containing protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 426.402 bits (1095), Expect = 3.992e-146
Identity = 196/315 (62.22%), Postives = 238/315 (75.56%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR-LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P+H PL+  LI+YVN   Q+TW A    RF+T++D+R +LGVL +PN   LP+ S   +A++ LP  FDSR QWP C +I EIRDQSNCGSCWAFGAVEAM+DR+CIHS G   P +SAEDLL+CCGF CG GCNGGFP GAW +W S GLVTGG+YG   GCQ Y+ P C HH  G Y  CTG+ PTPKC K C   Y  TY++DK FG ++YSV   E++IM EI+TNGPVE AF+VYADFP+YKSGVYQH +G  LGGHAI+ILGWG +  TPYWLVANSWN  WG++G+F+I +G +ECGIE  VVAG+PK
Sbjct:   24 PMHRPLTDSLIDYVNSQKQSTWTATRYNRFKTLADVRVLLGVLPNPNPSSLPELSYPESALKDLPEEFDSRKQWPNCPTIGEIRDQSNCGSCWAFGAVEAMSDRHCIHSGGKSKPYLSAEDLLSCCGFSCGMGCNGGFPEGAWHYWKSKGLVTGGQYGTKDGCQPYSLPHCEHHTTGEYQPCTGDSPTPKCTKQCIKEYNSTYQQDKHFGASAYSVRSNEQQIMTEIMTNGPVEGAFTVYADFPSYKSGVYQHTTGGSLGGHAIRILGWGADGGTPYWLVANSWNSDWGERGFFRILRGKDECGIESSVVAGLPK 338
[Close]
BLAST of cathepsin B vs. TrEMBL
Match: A0A267EIM2 (Pept_C1 domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033947g1 PE=3 SV=1)

HSP 1 Score: 427.172 bits (1097), Expect = 5.076e-146
Identity = 196/315 (62.22%), Postives = 238/315 (75.56%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIR-LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P+H PL+  LI+YVN   Q+TW A    RF+T++D+R +LGVL +PN   LP+ S   +A++ LP  FDSR QWP C +I EIRDQSNCGSCWAFGAVEAM+DR+CIHS G   P +SAEDLL+CCGF CG GCNGGFP GAW +W S GLVTGG+YG   GCQ Y+ P C HH  G Y  CTG+ PTPKC K C   Y  TY++DK FG ++YSV   E++IM EI+TNGPVE AF+VYADFP+YKSGVYQH +G  LGGHAI+ILGWG +  TPYWLVANSWN  WG++G+F+I +G +ECGIE  VVAG+PK
Sbjct:   49 PMHRPLTDSLIDYVNSQKQSTWTATRYNRFKTLADVRVLLGVLPNPNPSSLPELSYPESALKDLPEEFDSRKQWPNCPTIGEIRDQSNCGSCWAFGAVEAMSDRHCIHSGGKSKPHLSAEDLLSCCGFSCGMGCNGGFPEGAWHYWKSKGLVTGGQYGTKDGCQPYSLPHCEHHTTGEYQPCTGDSPTPKCTKQCIKEYNSTYQQDKHFGASAYSVRSNEQQIMTEIMTNGPVEGAFTVYADFPSYKSGVYQHTTGGSLGGHAIRILGWGADGGTPYWLVANSWNSDWGERGFFRILRGKDECGIESSVVAGLPK 363
[Close]
BLAST of cathepsin B vs. TrEMBL
Match: A0A183N7R8 (Pept_C1 domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS24343 PE=3 SV=1)

HSP 1 Score: 426.402 bits (1095), Expect = 5.297e-146
Identity = 196/313 (62.62%), Postives = 238/313 (76.04%), Query Frame = 2 
Query:  122 IHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            ++ PLS +LINY+NY A TTWKA PTTRF+TVSDIR++LG L DPNN +L    +G  +  LP SFD+R++WP C SI+EIRDQS+CGSCWAFGAVEAM+DR CI S G   P +SAE+L++CC   CG GCNGGFP  AW +W + G+VTG  Y    GCQ Y FP C HHV+GP P+C G+  TP CK TCQ GY  +Y++DK +G+  Y V    E IM+E++ NGPVE  F VYADFPNYKSGVYQHVSGA+LGGHA+++LGWG ENN PYWL+ANSWN  WGD GYFKI +G NECGIE++V AGIPK
Sbjct:   34 MYQPLSLELINYINYEANTTWKAAPTTRFRTVSDIRRMLGALPDPNNEQLEILCAGYTSDELPKSFDARVEWPHCPSISEIRDQSSCGSCWAFGAVEAMSDRICIKSKGKHKPFLSAENLVSCCS-SCGMGCNGGFPHSAWLYWKNQGIVTGDLYNTTNGCQPYEFPPCEHHVVGPLPSCGGDVETPPCKTTCQPGYNISYEKDKWYGEKVYRVHSNPEAIMRELMQNGPVEVDFEVYADFPNYKSGVYQHVSGALLGGHAVRLLGWGEENNVPYWLIANSWNSDWGDNGYFKIVRGKNECGIENDVNAGIPK 345
[Close]
BLAST of cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 357.451 bits (916), Expect = 1.629e-122
Identity = 178/313 (56.87%), Postives = 218/313 (69.65%), Query Frame = 2 
Query:  128 TPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            +PLS D++N +N  A TTW A         S ++ + G +LK P   +LP+       + LP +FDSR QWP C +I++IRDQ +CGSCWAFGAVEAM+DR CIHS G  +  ISAEDLL+CC   CG GC GGFP  AW FW  +GLVTGG Y + +GC+ Y+   C HHV G  P C+GE  TP C K C  GY  +Y ED+ +GK SYS+    ++IM EI  NGPVEAAF+VY DF  YK+GVYQH +GA+LGGHAIKILGWG EN+TPYWL ANSWN  WGDKGYFKI +G + CGIE E+VAGIPK+
Sbjct:   23 SPLSQDMVNTINK-ANTTWTAKLNFDNVDYSFLKSLCGTILKGP---RLPEMVQVEGKVDLPDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCD-ECGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKGYFKILRGQDHCGIESEMVAGIPKV 330
[Close]
BLAST of cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 343.969 bits (881), Expect = 1.595e-117
Identity = 174/312 (55.77%), Postives = 210/312 (67.31%), Query Frame = 2 
Query:  128 TPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            +PLS D++N +N  A TTW         TV  + +V G                   + LP +FDSR QWP C +I++IRDQ +CGSCWAFGAVEAM+DR CIHS G  +  ISAEDLL+CC   CG GC GGFP  AW FW  +GLVTGG Y + +GC+ Y+   C HHV G  P C+GE  TP C K C  GY  +Y ED+ +GK SYS+    ++IM EI  NGPVEAAF+VY DF  YK+GVYQH +GA+LGGHAIKILGWG EN+TPYWL ANSWN  WGDKGYFKI +G + CGIE E+VAGIPK+
Sbjct:   23 SPLSQDMVNTINK-ANTTW---------TVKCLVQVEG------------------KVDLPDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCD-ECGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKGYFKILRGQDHCGIESEMVAGIPKV 305
[Close]
BLAST of cathepsin B vs. Ensembl Cavefish
Match: ctsba (cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650])

HSP 1 Score: 343.969 bits (881), Expect = 1.239e-116
Identity = 175/295 (59.32%), Postives = 208/295 (70.51%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKG 1012
            LS  LIN+VN  A TTW+AG        S + ++ G +LK P   KLP        ++LP SFD R QWP C ++ EIRDQ +CGSCWAFGA EA++DR CIHSNG  +  IS+EDLLTCC   CG GCNGG+PS AW FW S GLV+GG Y +HLGC+ Y+   C HHV G  P CTGE   TP C+K C+ GY+ +YK+DK FGK SYSV   E++IMQE+  NGPVE AF+VY DF  YKSGVYQHVSG+ +GGHAIKILGWG EN TPYWL ANSWN  WG+ GYFKI +G
Sbjct:   25 LSDQLINHVNK-ANTTWRAGHNFPNADYSYVMQLCGTMLKGP---KLPVMVQYAGDMKLPESFDPREQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRICIHSNGKVSVEISSEDLLTCCD-SCGMGCNGGYPSAAWEFWESEGLVSGGLYNSHLGCRPYSIEPCEHHVNGSRPPCTGEGGDTPNCEKKCEPGYSVSYKQDKHFGKQSYSVPSDEKQIMQELYKNGPVEGAFTVYEDFLLYKSGVYQHVSGSAVGGHAIKILGWGKENGTPYWLAANSWNTDWGENGYFKILRG 314
[Close]
BLAST of cathepsin B vs. Ensembl Cavefish
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 323.168 bits (827), Expect = 2.303e-109
Identity = 162/289 (56.06%), Postives = 198/289 (68.51%), Query Frame = 2 
Query:  128 TPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKG 991
            +PLS D++N +N  A TTW A         S ++ + G +LK P   +LP+       + LP +FDSR QWP C +I++IRDQ +CGSCWAFGAVEAM+DR CIHS G  +  ISAEDLL+CC   CG GC GGFP  AW FW  +GLVTGG Y + +GC+ Y+   C HHV G  P C+GE  TP C K C  GY  +Y ED+ +GK SYS+    ++IM EI  NGPVEAAF+VY DF  YK+GVYQH +GA+LGGHAIKILGWG EN+TPYWL ANSWN  WGDKG
Sbjct:   23 SPLSQDMVNTINK-ANTTWTAKLNFDNVDYSFLKSLCGTILKGP---RLPEMVQVEGKVDLPDNFDSRDQWPDCHTISQIRDQGSCGSCWAFGAVEAMSDRICIHSGGKVSVEISAEDLLSCCD-ECGMGCFGGFPDAAWDFWTKNGLVTGGLYDSSIGCRPYSLAPCEHHVNGTRPPCSGEEKTPDCVKQCIDGYTPSYAEDRHYGKRSYSIPSDPKQIMAEIYKNGPVEAAFTVYEDFLLYKTGVYQHRTGAVLGGHAIKILGWGEENSTPYWLAANSWNNDWGDKG 306
[Close]
BLAST of cathepsin B vs. Ensembl Cavefish
Match: TINAGL1 (tubulointerstitial nephritis antigen like 1 [Source:NCBI gene;Acc:103033458])

HSP 1 Score: 150.984 bits (380), Expect = 5.927e-41
Identity = 103/323 (31.89%), Postives = 157/323 (48.61%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRF--QTVSD-IRKVLGVLKDPNNFKLPKKSSGLNAIR---LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAM--------LGGHAIKILGWGVENN-----TPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVV 1045
            +  D+I+ VN      W+A   ++F   T+ + +R  LG  + P+   +      +N      LP+ F++  +WP    I+E  DQ NC + WAF      +DR  I S G   P++S ++L++C   R   GC GG   GAW F    G+VT         C  ++ P+ +   +G     +      K + T +   + TY  D       Y +   E+EIM+EI+ NGPV+A   V+ DF  YKSG+Y+H +            G H+++I GWG E +       YW+ ANSW   WG+ GYF+I +G NEC IE  V+
Sbjct:  141 MEADMIHAVNR-GNYGWRASNYSQFWGMTLDEGLRYRLGT-RRPSRAIMSMNEIQMNMDHNEHLPSYFNAAEKWPG--KIHEPLDQGNCAASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISC-DTRNQGGCAGGRIDGAWWFLRRRGVVTEE-------CYPFSAPQHTPAEVGRCMMQSRSVGRGKRQATARCPNSHTYNNDIFQSTPPYRLSTNEKEIMKEIMDNGPVQAILEVHEDFFTYKSGIYRHTNVNYHKAPQYRNHGTHSVRITGWGEERDYTGRTHKYWIAANSWGKNWGEDGYFRIARGENECEIEAFVI 451
[Close]
BLAST of cathepsin B vs. Ensembl Sea Lamprey
Match: ctsbb (cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1])

HSP 1 Score: 389.808 bits (1000), Expect = 6.274e-136
Identity = 194/325 (59.69%), Postives = 234/325 (72.00%), Query Frame = 2 
Query:   95 TKSVKG-PIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            T+ V G  +P+  PLS  + NYVN +  TTW+AG      +V D+R++ G VL  P   KLP ++  ++   LP SFD+R QWP C +I E+RDQ +CGSCWAFGAVEAM+DR+CIHS G  NP +SAEDLL+CC   CG GC+GG+PS AW+FW S GLVTGG+Y +  GC+ Y+   C HHV G  P C+GE PTPKC   C  GY   YK DK FGK +Y++   E +I QEI  NGPVEAAF+VYADFP YKSGVYQHV+G  LGGHAIKILGWGVE   PYWLVANSWN  WGD GYFKI +G+NECGIEDE+VAG+P L
Sbjct:   14 TRLVAGRSVPLLPPLSKYMANYVNTLG-TTWQAGHAFNGASVEDVRRLCGTVLGGP---KLPTRTHKVSQ-SLPDSFDARTQWPNCPTIGELRDQGSCGSCWAFGAVEAMSDRFCIHSKGQVNPHVSAEDLLSCCD-ECGMGCDGGYPSQAWNFWTSTGLVTGGQYSSGQGCRPYSIKPCEHHVNGSRPPCSGEGPTPKCVHECVPGYTPHYKADKYFGKKAYNIDSDESQIKQEIFDNGPVEAAFTVYADFPQYKSGVYQHVAGEELGGHAIKILGWGVEGGVPYWLVANSWNADWGDHGYFKILRGSNECGIEDEIVAGLPSL 332
[Close]
BLAST of cathepsin B vs. Ensembl Sea Lamprey
Match: ctsc (cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9])

HSP 1 Score: 102.064 bits (253), Expect = 3.015e-24
Identity = 85/315 (26.98%), Postives = 140/315 (44.44%), Query Frame = 2 
Query:  170 AQTTWKAG---PTTRFQTVSDIRKVLG---VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQ-EILTNGPVEAAFSVYADFPNYKSGVYQHV------SGAMLGGHAIKILGWGVE------NNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            AQ++W+AG      R      +R+  G   ++ +          +   A  LPA++D R        ++ +RDQ  CGSC++F ++  +  R  I SN T+ P  S + +++C  +    GC+GGFP            +  G++    G  +    +  +  IG    C  + P+      C   Y   Y     F       G   EE+M+ E++ NGP+   F VY DF  Y+ G+Y H       +      HA+ ++G+G +         P+W+V NSW   WG+ GYF+I++G +EC  E   +A  P
Sbjct:  181 AQSSWRAGRYLDMERRPMEEIVRRSGGTGSIIPNRPRAAAASDETRRRAAVLPAAWDWR-DVRGVSYVSPVRDQGACGSCYSFASMAMLEARVRILSNNTQQPVFSPQHIVSCSPY--SQGCDGGFP-----------YLIAGKFAQDFGVIE----ESCYPYIGQDSKCLPKDPS------CLRYYTARYHYVGGF------YGACSEELMRLELVENGPLAIGFQVYDDFMAYQGGIYHHTGLRDQFNPFEETNHAVLLVGYGTDAAGPEGTGEPFWIVKNSWGEGWGEGGYFRIRRGNDECAFESIAMAATP 465
[Close]
BLAST of cathepsin B vs. Ensembl Sea Lamprey
Match: ctso (cathepsin O [Source:ZFIN;Acc:ZDB-GENE-080724-8])

HSP 1 Score: 95.1301 bits (235), Expect = 4.116e-23
Identity = 69/246 (28.05%), Postives = 111/246 (45.12%), Query Frame = 2 
Query:  305 LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEV 1042
            LP  FD    W   +++  +++Q +CG CWAF +V+ + +   + + G   P +S + +L C   R   GC GG    A+S W++   +       HL  +           + P+ N  G      C+       +    E K F   S+     EE +M  ++  GP+  +    + + +Y  GV QH   +    HA+ + G+ +  + PYW+V NSW P WG  GY  IK   N CGI +EV
Sbjct:   19 LPTHFD----WRDKRAVTAVKNQESCGGCWAFASVQ-VVESASVLAGGLLKP-LSVQQVLDCS--RVNHGCQGGDTVTAFS-WLNKTRL-------HLVLES----------VYPFTNSAG-----PCRIFTN---STPGVEIKDFASHSFLSSDDEEAMMGWLVGRGPLAVSVDAVS-WQDYLGGVVQHHCSSSAPNHAVTLTGYSLVGDLPYWIVRNSWGPEWGLDGYIYIKMFENVCGIANEV 229
[Close]
BLAST of cathepsin B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.1225 bits (222), Expect = 8.600e-21
Identity = 67/246 (27.24%), Postives = 112/246 (45.53%), Query Frame = 2 
Query:  308 PASFDS--RIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSV-YADFPNYKSGVYQHVSGAMLGGHAIKILGWGV-ENNTPYWLVANSWNPTWGDKGYFKIKKGTNE-CGI 1030
            PA F++   + W K   + +I++Q +CGSCW+F    ++  ++   +    +  +S ++L+ C       GCNGG    A+++   +G +   E               S+   G    C  +   PK K     GY +  +             G EE +M  + + GPV  A     A F +Y SG+Y+    +    HA+ ++G+GV E    +WLV NSW  TWG++GY ++ +  N  CGI
Sbjct:   72 PAFFEAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVS--LSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEE---------------SYPYKGQVETCKYD---PKNKAAEVTGYVEIPE-------------GDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSHHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGI 284
[Close]
BLAST of cathepsin B vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 83.1889 bits (204), Expect = 1.985e-18
Identity = 80/327 (24.46%), Postives = 140/327 (42.81%), Query Frame = 2 
Query:   74 RTKWESLTKSVKGPIPIHTPLSFDLINYVNYIAQTTWKAGPTTRF--QTVSDIRKVLGVLKDPN-NFKLPKKSSGLNAIRLPASFDS--RIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYAD-FPNYKSGVYQHVSGAMLGGHAIKILGWGV-ENNTPYWLVANSWNPTWGDKGYFKIKKGTNE-CGI 1030
            R  WE   K     I +H        N  + + + TW+ G   RF   T  + ++V+   +  N   K P+ ++       PA F++   + W K   + ++++Q +CGSCW+F    ++  ++   +    +  +S ++L+ C       GCNGG    A+++   +G +   E   + G        C ++              PK K     GY +  +             G EE +   + + GPV  A     + F  Y SG+Y+    + +  HA+ ++G+GV E    +WLV NSW   WG+KGY ++ +  N  CGI
Sbjct:    9 RMIWEQNLK----KIAVH--------NLEHSMGKHTWRMG-MNRFGDMTGEEFQQVMLGFRGWNGTSKAPRGAT----FMAPAFFEAPESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVS--LSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKG---QGVETCKYN--------------PKNKAAEVTGYVEIPE-------------GDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHIINHAVLVVGYGVDEKGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGI 286
[Close]
BLAST of cathepsin B vs. Ensembl Nematostella
Match: EDO34588 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNX0])

HSP 1 Score: 352.058 bits (902), Expect = 5.929e-122
Identity = 163/253 (64.43%), Postives = 191/253 (75.49%), Query Frame = 2 
Query:  305 LPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            +P  FDSR QWP C +I E+RDQ  CGSCWAFGAVEAM+DRYCI S G   P ISAEDLL+CC   CG GCNGG+P  AW  W S GLVTGG+Y +H GCQ Y    C HHV+G    C G+ PTPKC++ C+AGY  +Y +DK FG+++YSV     EI +EI+TNGPVE AF+VYADFP YKSGVYQH SG+ LGGHAIKILGWG EN TPYWLVANSWN  WGD+G+FKIK+G +ECGIE  +V G+PK 
Sbjct:    4 VPDHFDSREQWPHCPTIKEVRDQGACGSCWAFGAVEAMSDRYCIKSEGKVMPHISAEDLLSCC-ETCGMGCNGGYPESAWDHWKSKGLVTGGQYDSHKGCQPYKIAACDHHVVGKLKPCKGDSPTPKCERKCEAGYNVSYSDDKHFGQSAYSVRSDPAEIQKEIMTNGPVEGAFTVYADFPTYKSGVYQHTSGSALGGHAIKILGWGEENGTPYWLVANSWNSDWGDEGFFKIKRGNDECGIESGIVGGLPKF 255
[Close]
BLAST of cathepsin B vs. Ensembl Nematostella
Match: EDO38122 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDR5])

HSP 1 Score: 206.068 bits (523), Expect = 4.696e-64
Identity = 121/320 (37.81%), Postives = 171/320 (53.44%), Query Frame = 2 
Query:  113 PIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQ--TVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQ-EILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            PI     +S DL++ +N +    W+A    +F+  T    + +LG         LP +     A  +P +FD+R QWP   SI+ IR+Q  CGSCWAFGA E ++DR+ I S       +SA+ L+ C       GC+GG+P  AW++ V  GL+T   YG                     P    ++       T    +    K      K++Y +  +  E +Q +I+ NGPVEA F+++ DF  Y+SG+Y H +G  LGGHAIKILGWG E+N  YWL ANSW   WG +GYFKI++GT+ECGIED + AG+P L
Sbjct:   18 PISKEKVISRDLVDKINTL-NVGWEATLYPQFENLTFESAKSMLGSRGAWPEGSLPPEIEVRVAENIPENFDARKQWPG--SIHPIRNQGQCGSCWAFGASEVLSDRFAIASKNQIYVTLSAQQLVDCD--LDNSGCSGGWPINAWNYMVKTGLLTEQCYG---------------------PYYAKQYTCRLTANTTDCPWQPGVKARFYHAKSAYKLPAKNVEAIQTDIMNNGPVEADFTIFQDFYAYRSGIYVHATGKQLGGHAIKILGWGTEDNVDYWLCANSWGANWGIQGYFKIRRGTDECGIEDGLAAGLPLL 311
[Close]
BLAST of cathepsin B vs. Ensembl Nematostella
Match: EDO37120 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGN5])

HSP 1 Score: 95.9005 bits (237), Expect = 5.768e-23
Identity = 71/246 (28.86%), Postives = 102/246 (41.46%), Query Frame = 2 
Query:  290 LNAIRLPASFDSRIQWPKCKSINEIRDQSN------CGSCWAFGAVEAMTDRYCIHSNGT-KNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSY-SVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKI 1003
            LN  +LP SFD    W      N      N      CGSCWA G   AM DR  I   G   +  +S + +L C        C+GG   G + +  +HG+           C +Y       +V              KC      G     +  + +    Y +V GRE+ +M EI   GP+        +  NY  GVY+  + +    H + ++GWGVEN   YW+V NSW   WG++G+F+I
Sbjct:    6 LNMAKLPTSFD----WRDVNGTNYASTTRNQHIPQYCGSCWAHGTTSAMADRINILRKGKWPSAYLSVQHVLDCAN---AGTCHGGGMLGVYQYAQTHGI-------PDETCNNYQAKDQDCNVFN------------KCGTCTTFGKCHVIENYRLWKAEEYGNVNGREK-MMAEIFARGPIACGIMATPNLDNYTKGVYKEHNTSPEINHIVSVMGWGVENGEEYWVVRNSWGTPWGEEGFFRI 224
[Close]
BLAST of cathepsin B vs. Ensembl Nematostella
Match: EDO44165 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWG6])

HSP 1 Score: 88.5817 bits (218), Expect = 3.039e-19
Identity = 71/288 (24.65%), Postives = 114/288 (39.58%), Query Frame = 2 
Query:  209 QTVSDIRKVLGVLKDP------NNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHG-LVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVY-ADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVA 1048
             T +++ ++ G+L +       + F +P K  G   + LP   D    W K  ++N ++ Q  CGSC+AF    A+   + I +    +  +S + ++ C       GC GG+P  A  + + HG L T   YG +L  + Y                         K T        Y   +Q         G   ++   +   GPV    +     F  Y SG+Y          HA   +G+G E    YW+V NSW+  WG++GY KI    + CG+  + V 
Sbjct:  261 MTDAEVNRMKGLLHEEPPLIGDSPFSIPDKDRG---VPLPPHVD----WRKAGAVNSVKSQGICGSCYAFAVAGALEGAHFIKTGLKLD--LSEQQIVDCTWGFGNRGCKGGYPYRAMQWILKHGGLATEESYGRYLAQEGYC----------------------HFKNTSIGARLDKYMSIRQ---------GNTSQLKLAVAFYGPVSILVNTQPKTFKFYGSGIYYDTQCTHALDHAALAVGYGEEKGVSYWIVKNSWSAMWGEEGYIKIAMKDDNCGVAQKAVV 508
[Close]
BLAST of cathepsin B vs. Ensembl Nematostella
Match: EDO37121 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGN6])

HSP 1 Score: 83.1889 bits (204), Expect = 1.991e-18
Identity = 67/243 (27.57%), Postives = 95/243 (39.09%), Query Frame = 2 
Query:  305 LPASFDSRIQWPKCKSINEIRDQSN------CGSCWAFGAVEAMTDRYCIHSNGT-KNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGL--VTGGEYGA-HLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKI 1003
            +P +FD    W      N      N      CGSCWA G   AM DR  I   G   +  +S + +L C        C+GG   G + +  +HG+   T   Y A   GC D  F +C          CT  F      + C+      Y   +  G+         + +M EI   GP+       +    Y  GVY          H + ++GWGV++   YW+V NSW   WG+ G+ KI
Sbjct:   10 VPKAFD----WRDVNGTNYASTTRNQHIPQYCGSCWAHGTTSAMADRINILRKGKWPSAYLSVQHVLDCAD---AGTCHGGGMLGVYKYAQTHGIPDETCNNYQAKDQGCTD--FNQCG--------TCT-SFGDCHAIRVCKHWKVSEYGTSRVSGR---------DRMMAEIFARGPIACGIEATSRLEQYTGGVYTEYDPNPQINHIVSVVGWGVDDGVEYWVVRNSWGTPWGENGFLKI 225
[Close]
BLAST of cathepsin B vs. Ensembl Medaka
Match: ctsba (cathepsin B [Source:NCBI gene;Acc:101160638])

HSP 1 Score: 374.785 bits (961), Expect = 2.287e-129
Identity = 185/316 (58.54%), Postives = 223/316 (70.57%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS D++NY+N +  TTWKAG   +    S ++K+ G +LK P   KLP        ++LP  FD+R QWP C ++ EIRDQ +CGSCWAFGA EA++DR CIHSN   +  IS+EDLLTCC   CG GCNGG+P+ AW FW   GLVTGG Y +H+GC+ Y  P C HHV G  P CTGE   TP+C   C++GY  +YK+DK +GKTSYSV   E +I  EI  NGPVE AF VY DFP YKSGVYQHVSG+++GGHAIKILGWGVE+  PYWL ANSWN  WGD GYFKI +G++ CGIE EVVAGIPK
Sbjct:   20 PRFHPLSSDMVNYINKL-NTTWKAGHNFKNADYSYVQKLCGTMLKGP---KLPIMVQYAGDVKLPTEFDARAQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSNARVSVEISSEDLLTCCE-SCGMGCNGGYPTAAWDFWTKEGLVTGGLYDSHVGCRPYTIPPCEHHVNGTRPPCTGEGGDTPQCINQCESGYTPSYKKDKHYGKTSYSVEANENQIQTEIYKNGPVEGAFMVYEDFPMYKSGVYQHVSGSLIGGHAIKILGWGVEDGVPYWLCANSWNTDWGDNGYFKILRGSDHCGIESEVVAGIPK 330
[Close]
BLAST of cathepsin B vs. Ensembl Medaka
Match: ctsba (cathepsin B [Source:NCBI gene;Acc:101160638])

HSP 1 Score: 375.17 bits (962), Expect = 3.135e-129
Identity = 185/316 (58.54%), Postives = 223/316 (70.57%), Query Frame = 2 
Query:  119 PIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEF-PTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPK 1060
            P   PLS D++NY+N +  TTWKAG   +    S ++K+ G +LK P   KLP        ++LP  FD+R QWP C ++ EIRDQ +CGSCWAFGA EA++DR CIHSN   +  IS+EDLLTCC   CG GCNGG+P+ AW FW   GLVTGG Y +H+GC+ Y  P C HHV G  P CTGE   TP+C   C++GY  +YK+DK +GKTSYSV   E +I  EI  NGPVE AF VY DFP YKSGVYQHVSG+++GGHAIKILGWGVE+  PYWL ANSWN  WGD GYFKI +G++ CGIE EVVAGIPK
Sbjct:   42 PRFHPLSSDMVNYINKL-NTTWKAGHNFKNADYSYVQKLCGTMLKGP---KLPIMVQYAGDVKLPTEFDARAQWPNCPTLKEIRDQGSCGSCWAFGAAEAISDRVCIHSNARVSVEISSEDLLTCCE-SCGMGCNGGYPTAAWDFWTKEGLVTGGLYDSHVGCRPYTIPPCEHHVNGTRPPCTGEGGDTPQCINQCESGYTPSYKKDKHYGKTSYSVEANENQIQTEIYKNGPVEGAFMVYEDFPMYKSGVYQHVSGSLIGGHAIKILGWGVEDGVPYWLCANSWNTDWGDNGYFKILRGSDHCGIESEVVAGIPK 352
[Close]
BLAST of cathepsin B vs. Ensembl Medaka
Match: ctsbb (cathepsin B [Source:NCBI gene;Acc:101165526])

HSP 1 Score: 364.77 bits (935), Expect = 1.895e-125
Identity = 179/309 (57.93%), Postives = 220/309 (71.20%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLG-VLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            LS ++I++VN +  TTW AG     +  S ++ + G +LK P   KLP+ +  +  I+LP SFD R QWP C ++ +IRDQ NCGSCWAFGA EA++DR CI S G  +  ISAEDLLTCC   CG GC GGFPS AW FW + GLVTGG + + +GC+ Y    C HHV G  P C GE  TPKC   C  GY+ +Y +DK FG+ SYS+  ++E+IM E+  NGPVEAAFSVYADF  YK+GVYQHV+G MLGGHA+KILGWG EN TPYWLVANSWN  WGDKG+FKIK+G +ECGIE E+VAG P
Sbjct:   25 LSLEMIDFVNKL-NTTWTAGQNFHNKDSSFVKGLCGTILKGP---KLPELAHDVEGIKLPDSFDPREQWPNCPTLKQIRDQGNCGSCWAFGAAEAISDRICIQSGGKISLEISAEDLLTCCD-ECGMGCFGGFPSAAWEFWTNKGLVTGGLFDSKVGCRPYTLAPCEHHVNGSRPPCQGEVETPKCVTQCNNGYSLSYPKDKHFGQRSYSIPSQQEQIMTELYKNGPVEAAFSVYADFLLYKNGVYQHVTGDMLGGHAVKILGWGEENGTPYWLVANSWNSDWGDKGFFKIKRGNDECGIESEMVAGAP 328
[Close]
BLAST of cathepsin B vs. Ensembl Medaka
Match: TINAGL1 (tubulointerstitial nephritis antigen like 1 [Source:NCBI gene;Acc:101158958])

HSP 1 Score: 145.591 bits (366), Expect = 4.500e-39
Identity = 103/323 (31.89%), Postives = 151/323 (46.75%), Query Frame = 2 
Query:  134 LSFDLINYVNYIAQTTWKAGPTTRFQTVS---DIRKVLGVLKDPN---NFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAML--------GGHAIKILGWGVENN---TP--YWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVV 1045
            +  D+I+ VN      WKA   ++F  +S    IR  LG  +      N    +         LP  F+S  +WP    I+E  DQ NC + WAF      +DR  I S G   P++S ++L++C   R   GC GG   GAW +    G+VT         C  Y  P+ +   +G     +      K + T +      Y  D       Y +   E+EIM+EI+ NGPV+A   V+ DF  YK+G+Y+H   +          G H+++I GWG + +   TP  YW+ ANSW   WG+ G+F+I +G NEC IE  V+
Sbjct:  140 IEADIIHAVNR-GNYGWKAANYSQFFGMSLDEGIRYRLGTQRPSRTVMNMNEIQMKMDPQNDHLPRYFNSSEKWPN--KIHEPLDQGNCAASWAFSTAAVASDRISIQSMGHMTPQLSPQNLISC-DTRNQGGCAGGRIDGAWWYLRRRGVVTEN-------CYPYQPPQQAPAEVGRCMMQSRAVGRGKRQATQRCPNTYNYHNDIYQSTPPYKLSSNEKEIMKEIMENGPVQAIMEVHEDFFVYKNGIYKHTDVSSTKPPQYRKHGTHSVRITGWGEDKDYDGTPRKYWIAANSWGKNWGENGFFRIARGANECEIEAFVI 451
[Close]
BLAST of cathepsin B vs. Ensembl Medaka
Match: ctsc (cathepsin C [Source:NCBI gene;Acc:101170449])

HSP 1 Score: 120.939 bits (302), Expect = 3.880e-30
Identity = 90/323 (27.86%), Postives = 151/323 (46.75%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQ--TVSDIRKVLG--VLKDPNNFKLPKKSSGLN--AIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGA------MLGGHAIKILGWGVENNT--PYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAG--IPKL 1063
            D I+ +N + Q +W+A P    +  T+ ++    G    + P   +    ++ L   A  LP S+D R        ++ +R+Q+ CGSC++F  +  +  R  + +N ++ P  S + +++C  +    GC+GGFP     +    G+V           ++  FP  +       P            + C   Y   YK    F       G  E  +M+E++ +GP+  AF VY DF +Y  G+Y H   A       L  HA+ ++G+G  + T   YW+V NSW  +WG+ G+F+I++G++EC IE   VA   IPKL
Sbjct:  163 DFIHLINSV-QKSWRAAPHPEHEMYTLQELHYRAGGPASRVPVRVRPAPVTADLAKVAAALPESWDWR-NVGGVNFVSPVRNQAACGSCYSFATMGMLEARVRVLTNNSQTPVFSPQQVVSCSEY--SQGCDGGFPYLIGKYSQDFGIV-----------EESCFPYIAKDSPCGVP------------QNCGRAYTAEYKYVGGFYG-----GCSEMAMMKELVHHGPMAVAFEVYPDFMHYAGGIYHHTGLADPFNPFELTNHAVLLVGYGRCHKTGEKYWIVKNSWGTSWGENGFFRIRRGSDECSIESIAVAATPIPKL 453
[Close]
BLAST of cathepsin B vs. Planmine SMEST
Match: SMESG000048413.1 (SMESG000048413.1)

HSP 1 Score: 692.575 bits (1786), Expect = 0.000e+0
Identity = 332/333 (99.70%), Postives = 332/333 (99.70%), Query Frame = 2 
Query:   65 NCDRTKWESLTKSVKGPIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            NCDRTKWESLTKSVKG IPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL
Sbjct:   16 NCDRTKWESLTKSVKGQIPIHTPLSFDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 348
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BLAST of cathepsin B vs. Planmine SMEST
Match: SMESG000048415.1 (SMESG000048415.1)

HSP 1 Score: 504.212 bits (1297), Expect = 0.000e+0
Identity = 225/308 (73.05%), Postives = 269/308 (87.34%), Query Frame = 2 
Query:  140 FDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            F  IN V + AQTTWKA PTTRFQ+VSDIRKVLGV+KDPN+FKLP+K   ++ +  P SFD+R++W +C+SI E+RDQSNCGSCWAFGA  AMTDRYCIHSN T  PRIS+EDL++CCG +CGDGCNGGFP+GAW +WV+ G+VTGGEYG+H+GCQDYAFPKCSHHV G YPNCTGE+PTPKCK+ CQ+GY KTY+ DKQFGKTSYS+  +E +IM EI+ NGPVEA F VYADFPNY++GVYQHV+G +LGGHA+KI+GWG+ENNTPYWL+ANSWNPTWGD GYFKI +G NECGIEDE+VAG+P+L
Sbjct:    9 FKEINTV-FQAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 315
[Close]
BLAST of cathepsin B vs. Planmine SMEST
Match: SMESG000048414.1 (SMESG000048414.1)

HSP 1 Score: 504.212 bits (1297), Expect = 0.000e+0
Identity = 225/308 (73.05%), Postives = 269/308 (87.34%), Query Frame = 2 
Query:  140 FDLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPASFDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKILGWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            F  IN V + AQTTWKA PTTRFQ+VSDIRKVLGV+KDPN+FKLP+K   ++ +  P SFD+R++W +C+SI E+RDQSNCGSCWAFGA  AMTDRYCIHSN T  PRIS+EDL++CCG +CGDGCNGGFP+GAW +WV+ G+VTGGEYG+H+GCQDYAFPKCSHHV G YPNCTGE+PTPKCK+ CQ+GY KTY+ DKQFGKTSYS+  +E +IM EI+ NGPVEA F VYADFPNY++GVYQHV+G +LGGHA+KI+GWG+ENNTPYWL+ANSWNPTWGD GYFKI +G NECGIEDE+VAG+P+L
Sbjct:    9 FKEINTV-FQAQTTWKAAPTTRFQSVSDIRKVLGVMKDPNSFKLPQKKQLMSDMIFPDSFDARLEWSECESIREVRDQSNCGSCWAFGAAAAMTDRYCIHSNATYKPRISSEDLVSCCGEKCGDGCNGGFPTGAWHYWVTDGIVTGGEYGSHVGCQDYAFPKCSHHVKGIYPNCTGEYPTPKCKRNCQSGYPKTYRNDKQFGKTSYSISNKESDIMLEIMFNGPVEAGFDVYADFPNYRTGVYQHVAGGVLGGHAVKIIGWGIENNTPYWLIANSWNPTWGDNGYFKIIRGVNECGIEDEIVAGMPQL 315
[Close]
BLAST of cathepsin B vs. Planmine SMEST
Match: SMESG000077197.1 (SMESG000077197.1)

HSP 1 Score: 147.517 bits (371), Expect = 4.662e-40
Identity = 110/327 (33.64%), Postives = 152/327 (46.48%), Query Frame = 2 
Query:  143 DLINYVNYIAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPAS-FDSRIQWPKCKSIN---EIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQ-EILTNGPVEAAFSVYADFPNYKSGVYQHVSGA-------------MLGGHAIKILGWGVENNTP----YWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIP 1057
            DLIN  N     T K  P    +T+ DI ++ G     +N   PK +     +RL A  F     W     +N    +R Q +CGSC++F +   +  RY I SN T  P +S +D++ C  +    GCNGGFP            +  G+Y    G  D    KC+     PY    G+  T K    C+  YA  Y+    F       G   E +M+ E++ NGP+   F VY+DF  YK+G+Y HV  A              L  HA+ ++G+G    TP    YW+V NSW P WG+ GYFKI++G +ECGIE   VA  P
Sbjct:  162 DLINEKN--VGWTAKDYPEFHNRTLHDIIQMSGGFNSLHN--RPKSAPVTKIVRLTAEKFPKSFDWRNVNGVNFVSPVRSQGHCGSCYSFASAGMLEARYRIKSNNTIKPILSPQDVVECSPY--SQGCNGGFP-----------YLIAGKYAQDFGMAD---EKCN-----PYKGKDGKCSTIK---NCKRYYATKYQYLGGF------YGSTNEPLMRMELVINGPIAVGFEVYSDFRQYKNGIYHHVFKADNLMTSRFGFNPFELTNHAVLVVGYG---ETPAGEKYWIVKNSWGPKWGEGGYFKIRRGNDECGIESLAVASQP 451
[Close]
BLAST of cathepsin B vs. Planmine SMEST
Match: SMESG000077202.1 (SMESG000077202.1)

HSP 1 Score: 128.257 bits (321), Expect = 6.291e-33
Identity = 89/283 (31.45%), Postives = 131/283 (46.29%), Query Frame = 2 
Query:  272 PKKSSGLNAIR-LPASFDSRIQWPKCKSIN---EIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRISAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYAFPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVGGREEEIMQ-EILTNGPVEAAFSVYADFPNYKSGVYQH------VSGAMLG-------GHAIKILGWG-VENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL 1063
            P     LN+++ +P SFD    W     +N    +R+Q  CGSC++F +   +  RY I SN T +P +S +D++ C  +    GC GGFP            +  G++    G         +     PY    G+  T    K CQ  YA  YK    F       G   E +M+ E++ NGP+   F VY DF +Y+SGVY H      ++ +  G        HA+ ++G+G       +W V NSW   WG+ GYF+I++  +ECGIE   VA  P L
Sbjct:  205 PVTEYHLNSVKYIPKSFD----WRNVNGVNYVSPVRNQGGCGSCYSFASAGMLEARYRIKSNNTISPILSPQDVVECSPY--SQGCEGGFP-----------YLIAGKFAEDFGM--------AQESCNPYKGEDGKCST---TKNCQRYYATKYKYIGGF------YGATNEPLMRMELVRNGPIAVGFEVYDDFMSYQSGVYHHDFKTRKLTASKFGFNPFELTNHAVLVVGYGETATGEKFWTVKNSWGSGWGENGYFRIRRANDECGIESLGVASEPIL 453
The following BLAST results are available for this feature:
BLAST of cathepsin B vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSB4.376e-13459.68cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB4.376e-13459.68cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB4.376e-13459.68cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB4.376e-13459.68cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
CTSB4.376e-13459.68cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527][more]
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BLAST of cathepsin B vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpr-51.029e-11053.80Cathepsin B-like cysteine proteinase 5 [Source:Un... [more]
F57F5.13.949e-10448.77pep chromosome:WBcel235:V:12003028:12004600:1 gene... [more]
cpr-63.750e-10250.63Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
cpr-63.846e-10250.63Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
cpr-64.473e-10250.63Cathepsin B-like cysteine proteinase 6 [Source:Un... [more]
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BLAST of cathepsin B vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CtsB14.767e-11252.66gene:FBgn0030521 transcript:FBtr0346091[more]
CtsB14.767e-11252.66gene:FBgn0030521 transcript:FBtr0073838[more]
Swim1.152e-3730.87gene:FBgn0034709 transcript:FBtr0071785[more]
Swim1.152e-3730.87gene:FBgn0034709 transcript:FBtr0071784[more]
CG48471.567e-2027.56gene:FBgn0034229 transcript:FBtr0086935[more]
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BLAST of cathepsin B vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsba4.658e-12355.76cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
ctsbb7.902e-12255.84cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsba6.910e-9653.45cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
tinagl16.304e-3833.85tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
ctsc6.094e-3128.16cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9][more]
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BLAST of cathepsin B vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsb2.227e-13359.18cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb1.082e-12658.31cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb1.993e-12463.94cathepsin B [Source:NCBI gene;Acc:394833][more]
ctsb5.565e-12058.70cathepsin B [Source:NCBI gene;Acc:394833][more]
TINAGL17.701e-3631.19tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
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BLAST of cathepsin B vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsb1.665e-13560.32cathepsin B [Source:MGI Symbol;Acc:MGI:88561][more]
Tinagl17.446e-3931.79tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl17.446e-3931.79tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl17.446e-3931.79tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
Tinagl11.245e-3832.15tubulointerstitial nephritis antigen-like 1 [Sourc... [more]
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BLAST of cathepsin B vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P83205|CATB_SHEEP1.152e-13761.94Cathepsin B OS=Ovis aries OX=9940 GN=CTSB PE=1 SV=... [more]
sp|P00787|CATB_RAT2.238e-13660.32Cathepsin B OS=Rattus norvegicus OX=10116 GN=Ctsb ... [more]
sp|P10605|CATB_MOUSE1.165e-13460.32Cathepsin B OS=Mus musculus OX=10090 GN=Ctsb PE=1 ... [more]
sp|Q4R5M2|CATB_MACFA1.946e-13460.00Cathepsin B OS=Macaca fascicularis OX=9541 GN=CTSB... [more]
sp|A1E295|CATB_PIG8.074e-13460.32Cathepsin B OS=Sus scrofa OX=9823 GN=CTSB PE=1 SV=... [more]
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BLAST of cathepsin B vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JJ471.741e-14861.30cathepsin B OS=Lingula unguis OX=7574 GN=LOC106173... [more]
A0A1I8FYB72.468e-14662.22Pept_C1 domain-containing protein OS=Macrostomum l... [more]
A0A1I8JK493.992e-14662.22Pept_C1 domain-containing protein OS=Macrostomum l... [more]
A0A267EIM25.076e-14662.22Pept_C1 domain-containing protein (Fragment) OS=Ma... [more]
A0A183N7R85.297e-14662.62Pept_C1 domain-containing protein OS=Schistosoma m... [more]
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BLAST of cathepsin B vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsbb1.629e-12256.87cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsbb1.595e-11755.77cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsba1.239e-11659.32cathepsin Ba [Source:ZFIN;Acc:ZDB-GENE-040426-2650... [more]
ctsbb2.303e-10956.06cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
TINAGL15.927e-4131.89tubulointerstitial nephritis antigen like 1 [Sourc... [more]
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BLAST of cathepsin B vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsbb6.274e-13659.69cathepsin Bb [Source:ZFIN;Acc:ZDB-GENE-070323-1][more]
ctsc3.015e-2426.98cathepsin C [Source:ZFIN;Acc:ZDB-GENE-030619-9][more]
ctso4.116e-2328.05cathepsin O [Source:ZFIN;Acc:ZDB-GENE-080724-8][more]
ENSPMAT00000010475.18.600e-2127.24pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000003800.11.985e-1824.46pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g... [more]
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BLAST of cathepsin B vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of cathepsin B vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO345885.929e-12264.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO381224.696e-6437.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371205.768e-2328.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO441653.039e-1924.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371211.991e-1827.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of cathepsin B vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsba2.287e-12958.54cathepsin B [Source:NCBI gene;Acc:101160638][more]
ctsba3.135e-12958.54cathepsin B [Source:NCBI gene;Acc:101160638][more]
ctsbb1.895e-12557.93cathepsin B [Source:NCBI gene;Acc:101165526][more]
TINAGL14.500e-3931.89tubulointerstitial nephritis antigen like 1 [Sourc... [more]
ctsc3.880e-3027.86cathepsin C [Source:NCBI gene;Acc:101170449][more]
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BLAST of cathepsin B vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048413.10.000e+099.70SMESG000048413.1[more]
SMESG000048415.10.000e+073.05SMESG000048415.1[more]
SMESG000048414.10.000e+073.05SMESG000048414.1[more]
SMESG000077197.14.662e-4033.64SMESG000077197.1[more]
SMESG000077202.16.291e-3331.45SMESG000077202.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001635 ID=SMED30001635|Name=cathepsin B|organism=Schmidtea mediterranea sexual|type=transcript|length=1115bp
AGGCTAATTTTATGTAATGATGAAAATTATTTTGATTAGTTTTGTTCTTT
TATTTTCACTTGTCAATTGTGACCGAACGAAATGGGAATCTTTAACAAAA
AGCGTAAAGGGTCCAATTCCGATTCATACACCACTGTCTTTTGATTTGAT
CAACTACGTTAATTACATTGCTCAGACTACTTGGAAAGCAGGACCTACTA
CTAGATTCCAAACCGTTTCCGACATAAGAAAGGTTCTTGGGGTTTTGAAA
GATCCGAATAATTTCAAGCTGCCAAAGAAAAGTTCAGGATTGAATGCAAT
TAGACTTCCTGCTTCTTTTGATTCGAGAATTCAATGGCCTAAATGCAAAT
CTATTAATGAAATAAGAGACCAAAGCAACTGTGGATCATGCTGGGCATTT
GGAGCTGTTGAAGCAATGACTGATAGATATTGTATTCATTCCAATGGAAC
TAAGAATCCACGCATTAGTGCTGAAGATTTATTGACTTGTTGCGGTTTTA
GATGTGGGGATGGATGCAATGGAGGTTTTCCTAGTGGAGCTTGGAGTTTC
TGGGTTTCTCATGGATTAGTAACTGGAGGAGAATATGGTGCTCATTTAGG
GTGTCAAGATTATGCTTTCCCCAAGTGTTCTCATCATGTTATTGGTCCTT
ATCCTAATTGCACTGGTGAATTTCCAACCCCTAAATGCAAAAAGACATGC
CAAGCCGGTTATGCTAAAACCTATAAAGAAGATAAGCAATTCGGCAAAAC
ATCATATTCGGTTGGTGGTAGAGAAGAAGAAATTATGCAAGAAATCTTAA
CAAATGGTCCAGTAGAAGCTGCGTTTAGTGTTTACGCTGATTTCCCGAAT
TACAAATCAGGAGTGTATCAACATGTTTCCGGTGCAATGCTGGGTGGACA
TGCAATAAAAATCCTAGGTTGGGGAGTCGAAAACAACACTCCATATTGGC
TAGTAGCCAATTCTTGGAATCCGACATGGGGCGACAAAGGATATTTCAAA
ATCAAAAAGGGCACAAATGAATGTGGAATAGAAGATGAAGTTGTTGCTGG
AATACCAAAATTATAAATTACAGTTTTTCAACTTTCAAATTTTTAAATAT
ATTTGATTTTTTTTG
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protein sequence of SMED30001635-orf-1

>SMED30001635-orf-1 ID=SMED30001635-orf-1|Name=SMED30001635-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=350bp
MMKIILISFVLLFSLVNCDRTKWESLTKSVKGPIPIHTPLSFDLINYVNY
IAQTTWKAGPTTRFQTVSDIRKVLGVLKDPNNFKLPKKSSGLNAIRLPAS
FDSRIQWPKCKSINEIRDQSNCGSCWAFGAVEAMTDRYCIHSNGTKNPRI
SAEDLLTCCGFRCGDGCNGGFPSGAWSFWVSHGLVTGGEYGAHLGCQDYA
FPKCSHHVIGPYPNCTGEFPTPKCKKTCQAGYAKTYKEDKQFGKTSYSVG
GREEEIMQEILTNGPVEAAFSVYADFPNYKSGVYQHVSGAMLGGHAIKIL
GWGVENNTPYWLVANSWNPTWGDKGYFKIKKGTNECGIEDEVVAGIPKL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002075pigment cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR038765Papain-like_cys_pep_sf
IPR012599Propeptide_C1A
IPR000169Pept_cys_AS
IPR025660Pept_his_AS
IPR025661Pept_asp_AS
IPR000668Peptidase_C1A_C
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
GO:0050790regulation of catalytic activity
GO:0030574collagen catabolic process
GO:0030855epithelial cell differentiation
GO:0046697decidualization
GO:0046718viral entry into host cell
GO:0051603proteolysis involved in cellular protein catabolic process
GO:0097067cellular response to thyroid hormone stimulus
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0004197cysteine-type endopeptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
GO:0043394proteoglycan binding
GO:0005518collagen binding
Vocabulary: cellular component
TermDefinition
GO:0005764lysosome
GO:0042470melanosome
GO:0043231intracellular membrane-bounded organelle
GO:0048471perinuclear region of cytoplasm
GO:0070062extracellular exosome
GO:0005576extracellular region
GO:0005615extracellular space
GO:0005730nucleolus
GO:0005739mitochondrion
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 309..315
score: 68.95
coord: 294..304
score: 41.16
coord: 118..133
score: 55.78
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 96..345
e-value: 2.2E-101
score: 352.8
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 96..344
e-value: 6.8E-67
score: 225.7
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 33..348
e-value: 4.5E-115
score: 386.6
NoneNo IPR availablePANTHERPTHR12411:SF606coord: 39..342
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 39..342
NoneNo IPR availableCDDcd02620Peptidase_C1A_CathepsinBcoord: 97..344
e-value: 8.00009E-149
score: 417.057
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..17
score: 0.842
IPR012599Peptidase C1A, propeptidePFAMPF08127Propeptide_C1coord: 39..79
e-value: 5.6E-11
score: 42.2
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 309..328
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 118..129
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 292..302
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 40..347