E3 SUMO-protein ligase PIAS1

Overview


Name	E3 SUMO-protein ligase PIAS1
Smed ID	SMED30001604
Length (bp)	2598

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of E3 SUMO-protein ligase PIAS1 (SMED30001604) t-SNE clustered cells

Violin plots show distribution of expression levels for E3 SUMO-protein ligase PIAS1 (SMED30001604) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of E3 SUMO-protein ligase PIAS1 (SMED30001604) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for E3 SUMO-protein ligase PIAS1 (SMED30001604) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001604

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
epidermis	SMED30001604	h1SMcG0013474	dd_Smed_v4_10185_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Match: PIAS2 (protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311])

HSP 1 Score: 120.553 bits (301), Expect = 1.038e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC--SDVDEIKFQEDGSWCP 426

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Match: PIAS2 (protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311])

HSP 1 Score: 119.783 bits (299), Expect = 1.361e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  271 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 455

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Match: PIAS2 (protein inhibitor of activated STAT 2 [Source:HGNC Symbol;Acc:HGNC:17311])

HSP 1 Score: 120.168 bits (300), Expect = 2.046e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 426

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Match: PIAS1 (protein inhibitor of activated STAT 1 [Source:HGNC Symbol;Acc:HGNC:2752])

HSP 1 Score: 119.013 bits (297), Expect = 5.967e-27
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGTWAP-MRSKKEVQEVSASYNGV 432

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Match: PIAS1 (protein inhibitor of activated STAT 1 [Source:HGNC Symbol;Acc:HGNC:2752])

HSP 1 Score: 119.013 bits (297), Expect = 5.968e-27
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  144 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGTWAP-MRSKKEVQEVSASYNGV 434

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
Match: gei-17 (E3 SUMO-protein ligase gei-17 [Source:UniProtKB/Swiss-Prot;Acc:Q94361])

HSP 1 Score: 103.219 bits (256), Expect = 2.143e-22
Identity = 87/311 (27.97%), Postives = 148/311 (47.59%), Query Frame = 2

Query:   20 NNDYRIFNLLSKNMETARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHK-SNKFDIRAI------IRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKF------LIQWVQDDCKKESFYFAVYLVRRRTCEELSQIL---MKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGIL 904
            N +Y    + + N E       PFY+ I  ++   +L  ++            +  L+ + QL   FLL+     K S + D+  +      +RF N+ +      Q   KD FP++    ++++++ LP  +P ++T  + +R  RPV+++  +       N++       ++W+ D   K  +   VY V R   + L + L   + +  S     Q  I + S     G +DD+ +  + +N SL+ P+ + RM+TP R Q CTHLQCFD ++YL+MN  KPTWQCPVC     +  L VD   L +L
Sbjct:   80 NGNYEPKKMYADNFEPLPL---PFYDVISVLLKPVELHSSD------------SPTLKQTKQLQFPFLLTAEHISKISYRADVTPLPRYELQLRFFNLTE----PVQGPQKDDFPLNCYARVDDSVVQLPNVIPTNKTNAEPKRPSRPVNITSNM-------NRYKKEHTVAVEWLAD---KRVWAAGVYFVHRVNSDILFKRLNQNVSRHRSLEVTKQEVIKKLS-----GGEDDIAM--DRLNISLLDPLCKTRMTTPSRCQDCTHLQCFDLLSYLMMNEKKPTWQCPVCSSNCPYDRLIVDDYFLDML 354

[Close]

Query:   20 NNDYRIFNLLSKNMETARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHK-SNKFDIRAI------IRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKF------LIQWVQDDCKKESFYFAVYLVRRRTCEELSQIL---MKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGIL 904
            N +Y    + + N E       PFY+ I  ++   +L  ++            +  L+ + QL   FLL+     K S + D+  +      +RF N+ +      Q   KD FP++    ++++++ LP  +P ++T  + +R  RPV+++  +       N++       ++W+ D   K  +   VY V R   + L + L   + +  S     Q  I + S     G +DD+ +  + +N SL+ P+ + RM+TP R Q CTHLQCFD ++YL+MN  KPTWQCPVC     +  L VD   L +L
Sbjct:   80 NGNYEPKKMYADNFEPLPL---PFYDVISVLLKPVELHSSD------------SPTLKQTKQLQFPFLLTAEHISKISYRADVTPLPRYELQLRFFNLTE----PVQGPQKDDFPLNCYARVDDSVVQLPNVIPTNKTNAEPKRPSRPVNITSNM-------NRYKKEHTVAVEWLAD---KRVWAAGVYFVHRVNSDILFKRLNQNVSRHRSLEVTKQEVIKKLS-----GGEDDIAM--DRLNISLLDPLCKTRMTTPSRCQDCTHLQCFDLLSYLMMNEKKPTWQCPVCSSNCPYDRLIVDDYFLDML 354

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
Match: gei-17 (E3 SUMO-protein ligase gei-17 [Source:UniProtKB/Swiss-Prot;Acc:Q94361])

HSP 1 Score: 102.834 bits (255), Expect = 3.355e-22
Identity = 83/289 (28.72%), Postives = 141/289 (48.79%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHK-SNKFDIRAI------IRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKF------LIQWVQDDCKKESFYFAVYLVRRRTCEELSQIL---MKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGIL 904
            PFY+ I  ++   +L  ++            +  L+ + QL   FLL+     K S + D+  +      +RF N+ +      Q   KD FP++    ++++++ LP  +P ++T  + +R  RPV+++  +       N++       ++W+ D   K  +   VY V R   + L + L   + +  S     Q  I + S     G +DD+ +  + +N SL+ P+ + RM+TP R Q CTHLQCFD ++YL+MN  KPTWQCPVC     +  L VD   L +L
Sbjct:  166 PFYDVISVLLKPVELHSSD------------SPTLKQTKQLQFPFLLTAEHISKISYRADVTPLPRYELQLRFFNLTE----PVQGPQKDDFPLNCYARVDDSVVQLPNVIPTNKTNAEPKRPSRPVNITSNM-------NRYKKEHTVAVEWLAD---KRVWAAGVYFVHRVNSDILFKRLNQNVSRHRSLEVTKQEVIKKLS-----GGEDDIAM--DRLNISLLDPLCKTRMTTPSRCQDCTHLQCFDLLSYLMMNEKKPTWQCPVCSSNCPYDRLIVDDYFLDML 421

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
Match: gei-17 (E3 SUMO-protein ligase gei-17 [Source:UniProtKB/Swiss-Prot;Acc:Q94361])

HSP 1 Score: 102.834 bits (255), Expect = 3.355e-22
Identity = 83/289 (28.72%), Postives = 141/289 (48.79%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHK-SNKFDIRAI------IRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKF------LIQWVQDDCKKESFYFAVYLVRRRTCEELSQIL---MKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGIL 904
            PFY+ I  ++   +L  ++            +  L+ + QL   FLL+     K S + D+  +      +RF N+ +      Q   KD FP++    ++++++ LP  +P ++T  + +R  RPV+++  +       N++       ++W+ D   K  +   VY V R   + L + L   + +  S     Q  I + S     G +DD+ +  + +N SL+ P+ + RM+TP R Q CTHLQCFD ++YL+MN  KPTWQCPVC     +  L VD   L +L
Sbjct:  166 PFYDVISVLLKPVELHSSD------------SPTLKQTKQLQFPFLLTAEHISKISYRADVTPLPRYELQLRFFNLTE----PVQGPQKDDFPLNCYARVDDSVVQLPNVIPTNKTNAEPKRPSRPVNITSNM-------NRYKKEHTVAVEWLAD---KRVWAAGVYFVHRVNSDILFKRLNQNVSRHRSLEVTKQEVIKKLS-----GGEDDIAM--DRLNISLLDPLCKTRMTTPSRCQDCTHLQCFDLLSYLMMNEKKPTWQCPVCSSNCPYDRLIVDDYFLDML 421

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
Match: gei-17 (E3 SUMO-protein ligase gei-17 [Source:UniProtKB/Swiss-Prot;Acc:Q94361])

HSP 1 Score: 102.834 bits (255), Expect = 3.355e-22
Identity = 83/289 (28.72%), Postives = 141/289 (48.79%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHK-SNKFDIRAI------IRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKF------LIQWVQDDCKKESFYFAVYLVRRRTCEELSQIL---MKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGIL 904
            PFY+ I  ++   +L  ++            +  L+ + QL   FLL+     K S + D+  +      +RF N+ +      Q   KD FP++    ++++++ LP  +P ++T  + +R  RPV+++  +       N++       ++W+ D   K  +   VY V R   + L + L   + +  S     Q  I + S     G +DD+ +  + +N SL+ P+ + RM+TP R Q CTHLQCFD ++YL+MN  KPTWQCPVC     +  L VD   L +L
Sbjct:  166 PFYDVISVLLKPVELHSSD------------SPTLKQTKQLQFPFLLTAEHISKISYRADVTPLPRYELQLRFFNLTE----PVQGPQKDDFPLNCYARVDDSVVQLPNVIPTNKTNAEPKRPSRPVNITSNM-------NRYKKEHTVAVEWLAD---KRVWAAGVYFVHRVNSDILFKRLNQNVSRHRSLEVTKQEVIKKLS-----GGEDDIAM--DRLNISLLDPLCKTRMTTPSRCQDCTHLQCFDLLSYLMMNEKKPTWQCPVCSSNCPYDRLIVDDYFLDML 421

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Match: Su(var)2-10 (gene:FBgn0003612 transcript:FBtr0343996)

HSP 1 Score: 129.028 bits (323), Expect = 9.782e-31
Identity = 84/254 (33.07%), Postives = 127/254 (50.00%), Query Frame = 2

Query:  266 RAIIRFSNIEDVHKVDDQFTL-------KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVI-FNKIGQWKPDNKTPGMTNDDE 1003
            R I   S +E   +V  +F L       +D FP ++ + +NN L  LP  +P +R   + +R PRPV+++  +  +P V N   +QW  D  +  S+  AVYLV++ T  +L Q +  K + P   T+  I E        +D D  +    +  SL CP+ +++M  P R   C+HLQCFD   YL MN  KPTW CPVCDK   +  L +D     +L     KS D  I  ++ G W     TPG+ ++ +
Sbjct:  221 RDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTR--SYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKE-----KLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGLRSETQ 463

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Match: Su(var)2-10 (gene:FBgn0003612 transcript:FBtr0306705)

HSP 1 Score: 128.642 bits (322), Expect = 1.065e-30
Identity = 84/254 (33.07%), Postives = 127/254 (50.00%), Query Frame = 2

Query:  266 RAIIRFSNIEDVHKVDDQFTL-------KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVI-FNKIGQWKPDNKTPGMTNDDE 1003
            R I   S +E   +V  +F L       +D FP ++ + +NN L  LP  +P +R   + +R PRPV+++  +  +P V N   +QW  D  +  S+  AVYLV++ T  +L Q +  K + P   T+  I E        +D D  +    +  SL CP+ +++M  P R   C+HLQCFD   YL MN  KPTW CPVCDK   +  L +D     +L     KS D  I  ++ G W     TPG+ ++ +
Sbjct:  221 RDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTR--SYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKE-----KLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGLRSETQ 463

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Match: Su(var)2-10 (gene:FBgn0003612 transcript:FBtr0088571)

HSP 1 Score: 128.642 bits (322), Expect = 1.134e-30
Identity = 84/254 (33.07%), Postives = 127/254 (50.00%), Query Frame = 2

Query:  266 RAIIRFSNIEDVHKVDDQFTL-------KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVI-FNKIGQWKPDNKTPGMTNDDE 1003
            R I   S +E   +V  +F L       +D FP ++ + +NN L  LP  +P +R   + +R PRPV+++  +  +P V N   +QW  D  +  S+  AVYLV++ T  +L Q +  K + P   T+  I E        +D D  +    +  SL CP+ +++M  P R   C+HLQCFD   YL MN  KPTW CPVCDK   +  L +D     +L     KS D  I  ++ G W     TPG+ ++ +
Sbjct:  221 RDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTR--SYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKE-----KLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGLRSETQ 463

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Match: Su(var)2-10 (gene:FBgn0003612 transcript:FBtr0088570)

HSP 1 Score: 129.413 bits (324), Expect = 1.156e-30
Identity = 84/254 (33.07%), Postives = 127/254 (50.00%), Query Frame = 2

Query:  266 RAIIRFSNIEDVHKVDDQFTL-------KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVI-FNKIGQWKPDNKTPGMTNDDE 1003
            R I   S +E   +V  +F L       +D FP ++ + +NN L  LP  +P +R   + +R PRPV+++  +  +P V N   +QW  D  +  S+  AVYLV++ T  +L Q +  K + P   T+  I E        +D D  +    +  SL CP+ +++M  P R   C+HLQCFD   YL MN  KPTW CPVCDK   +  L +D     +L     KS D  I  ++ G W     TPG+ ++ +
Sbjct:  221 RDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTR--SYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKE-----KLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGLRSETQ 463

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Match: Su(var)2-10 (gene:FBgn0003612 transcript:FBtr0088576)

HSP 1 Score: 128.257 bits (321), Expect = 1.166e-30
Identity = 84/254 (33.07%), Postives = 127/254 (50.00%), Query Frame = 2

Query:  266 RAIIRFSNIEDVHKVDDQFTL-------KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVI-FNKIGQWKPDNKTPGMTNDDE 1003
            R I   S +E   +V  +F L       +D FP ++ + +NN L  LP  +P +R   + +R PRPV+++  +  +P V N   +QW  D  +  S+  AVYLV++ T  +L Q +  K + P   T+  I E        +D D  +    +  SL CP+ +++M  P R   C+HLQCFD   YL MN  KPTW CPVCDK   +  L +D     +L     KS D  I  ++ G W     TPG+ ++ +
Sbjct:  174 RDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTR--SYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKE-----KLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGLRSETQ 416

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Match: pias1a (protein inhibitor of activated STAT, 1a [Source:ZFIN;Acc:ZDB-GENE-120727-5])

HSP 1 Score: 121.324 bits (303), Expect = 5.666e-28
Identity = 90/314 (28.66%), Postives = 145/314 (46.18%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P  ++     +  +SYN I
Sbjct:  131 PFYDLLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQVSSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLIRLSTTVPNTIVVSWTSEIGR--SYSLAVYLVKQLSSTMLLQRLRGKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNSCL--DCDEIQFKEDGSWAP-MRSKKEVQEVSASYNGI 421

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Match: pias1a (protein inhibitor of activated STAT, 1a [Source:ZFIN;Acc:ZDB-GENE-120727-5])

HSP 1 Score: 121.324 bits (303), Expect = 5.739e-28
Identity = 90/314 (28.66%), Postives = 145/314 (46.18%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P  ++     +  +SYN I
Sbjct:  139 PFYDLLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQVSSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLIRLSTTVPNTIVVSWTSEIGR--SYSLAVYLVKQLSSTMLLQRLRGKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNSCL--DCDEIQFKEDGSWAP-MRSKKEVQEVSASYNGI 429

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Match: pias1b (protein inhibitor of activated STAT, 1b [Source:ZFIN;Acc:ZDB-GENE-050419-202])

HSP 1 Score: 121.324 bits (303), Expect = 6.637e-28
Identity = 86/296 (29.05%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL+       D + F + G W P
Sbjct:  133 PFYDVLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILSS--CVDCDEIQFKEDGNWSP 406

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Match: BX890624.1 (protein inhibitor of activated STAT, 1b [Source:NCBI gene;Acc:562982])

HSP 1 Score: 120.939 bits (302), Expect = 7.252e-28
Identity = 86/296 (29.05%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL+       D + F + G W P
Sbjct:  126 PFYDVLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILSS--CVDCDEIQFKEDGNWSP 399

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Match: CR450724.1 (protein inhibitor of activated STAT, 1b [Source:NCBI gene;Acc:562982])

HSP 1 Score: 120.939 bits (302), Expect = 7.252e-28
Identity = 86/296 (29.05%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL+       D + F + G W P
Sbjct:  126 PFYDVLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILSS--CVDCDEIQFKEDGNWSP 399

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Match: mgc76132 (Ferritin, lower subunit (Ferritin L) [Source:Xenbase;Acc:XB-GENE-5756459])

HSP 1 Score: 117.472 bits (293), Expect = 6.248e-27
Identity = 83/300 (27.67%), Postives = 140/300 (46.67%), Query Frame = 2

Query:   68 ARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
             R V  PFY+ +D ++  T+L   N          + +    F L      L+  S+        ++ ++R    +     +DQ+      P ++ + +N+   ++P + P+++ G + +R  RP++L+  L+      N+  + W       +S+   +YLVR+RT  EL Q L    +   +  +  + E         D D  +    +  SLICP+ ++R++ P R + C HLQCFD V YL MN  KPTW CPVCDK   +  L +D L+  IL++   K  D + F   G W P
Sbjct:  140 VRLVKLPFYDVVDELLKPTELVAQN-------NEKLQDSPCVFVLSPRQVDLIKNSRDLHPGTKSVQVVLRICYTDTSCPQEDQY------PPNVAVKVNHNYCSVPGYYPSNKPGVEPKRPCRPINLT-NLMYLSSASNRVTVTWGN---YGKSYSVGLYLVRQRTSSELLQRLKTIGVKHPELCKTLVRE-----KLRLDPDSEIATTGVRVSLICPLVKMRLTVPCRAETCAHLQCFDAVFYLQMNEKKPTWTCPVCDKPALYDQLIIDGLLSKILSE--CKDADEIEFLADGSWCP 415

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Match: PIAS1 (protein inhibitor of activated STAT 1 [Source:NCBI gene;Acc:100488714])

HSP 1 Score: 118.627 bits (296), Expect = 7.076e-27
Identity = 88/314 (28.03%), Postives = 145/314 (46.18%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  +F  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  141 PFYDLLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NFSLAVYLVKQLSSAILLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRSLTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKC--CTDCDEIQFKEDGSWSP-MRSKKEVQEVTTSYNGV 431

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Match: PIAS1 (protein inhibitor of activated STAT 1 [Source:NCBI gene;Acc:100488714])

HSP 1 Score: 118.627 bits (296), Expect = 7.363e-27
Identity = 88/314 (28.03%), Postives = 145/314 (46.18%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  +F  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NFSLAVYLVKQLSSAILLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRSLTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKC--CTDCDEIQFKEDGSWSP-MRSKKEVQEVTTSYNGV 432

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Match: mgc76132 (Ferritin, lower subunit (Ferritin L) [Source:Xenbase;Acc:XB-GENE-5756459])

HSP 1 Score: 117.087 bits (292), Expect = 7.366e-27
Identity = 83/300 (27.67%), Postives = 140/300 (46.67%), Query Frame = 2

Query:   68 ARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
             R V  PFY+ +D ++  T+L   N          + +    F L      L+  S+        ++ ++R    +     +DQ+      P ++ + +N+   ++P + P+++ G + +R  RP++L+  L+      N+  + W       +S+   +YLVR+RT  EL Q L    +   +  +  + E         D D  +    +  SLICP+ ++R++ P R + C HLQCFD V YL MN  KPTW CPVCDK   +  L +D L+  IL++   K  D + F   G W P
Sbjct:  140 VRLVKLPFYDVVDELLKPTELVAQN-------NEKLQDSPCVFVLSPRQVDLIKNSRDLHPGTKSVQVVLRICYTDTSCPQEDQY------PPNVAVKVNHNYCSVPGYYPSNKPGVEPKRPCRPINLT-NLMYLSSASNRVTVTWGN---YGKSYSVGLYLVRQRTSSELLQRLKTIGVKHPELCKTLVRE-----KLRLDPDSEIATTGVRVSLICPLVKMRLTVPCRAETCAHLQCFDAVFYLQMNEKKPTWTCPVCDKPALYDQLIIDGLLSKILSE--CKDADEIEFLADGSWCP 415

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Match: PIAS1 (protein inhibitor of activated STAT 1 [Source:NCBI gene;Acc:100488714])

HSP 1 Score: 118.242 bits (295), Expect = 7.614e-27
Identity = 88/314 (28.03%), Postives = 145/314 (46.18%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  +F  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  134 PFYDLLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NFSLAVYLVKQLSSAILLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRSLTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKC--CTDCDEIQFKEDGSWSP-MRSKKEVQEVTTSYNGV 424

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Match: Pias2 (protein inhibitor of activated STAT 2 [Source:MGI Symbol;Acc:MGI:1096566])

HSP 1 Score: 120.168 bits (300), Expect = 8.778e-28
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  235 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC--SDVDEIKFQEDGSWCP 419

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Match: Pias2 (protein inhibitor of activated STAT 2 [Source:MGI Symbol;Acc:MGI:1096566])

HSP 1 Score: 119.783 bits (299), Expect = 1.590e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 426

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Match: Pias2 (protein inhibitor of activated STAT 2 [Source:MGI Symbol;Acc:MGI:1096566])

HSP 1 Score: 119.783 bits (299), Expect = 1.598e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  235 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 419

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Match: Pias1 (protein inhibitor of activated STAT 1 [Source:MGI Symbol;Acc:MGI:1913125])

HSP 1 Score: 119.398 bits (298), Expect = 2.589e-27
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--TYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGSWAP-MRSKKEVQEVTASYNGV 432

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BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Match: Pias1 (protein inhibitor of activated STAT 1 [Source:MGI Symbol;Acc:MGI:1913125])

HSP 1 Score: 118.242 bits (295), Expect = 4.497e-27
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--TYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGSWAP-MRSKKEVQEVTASYNGV 432

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BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Match: sp|Q6AZ28|PIAS2_RAT (E3 SUMO-protein ligase PIAS2 OS=Rattus norvegicus OX=10116 GN=Pias2 PE=1 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 5.755e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDC--SDVDEIKFQEDGSWCP 426

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Match: sp|O75928|PIAS2_HUMAN (E3 SUMO-protein ligase PIAS2 OS=Homo sapiens OX=9606 GN=PIAS2 PE=1 SV=3)

HSP 1 Score: 120.168 bits (300), Expect = 9.825e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 426

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BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Match: sp|Q8C5D8|PIAS2_MOUSE (E3 SUMO-protein ligase PIAS2 OS=Mus musculus OX=10090 GN=Pias2 PE=1 SV=2)

HSP 1 Score: 119.783 bits (299), Expect = 1.112e-26
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P + P  + G + +R  RP++++  +  +  V N+  I W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILND     +D + F + G W P
Sbjct:  242 PGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGK--NYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILND--CSDVDEIKFQEDGSWCP 426

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Match: sp|O88907|PIAS1_MOUSE (E3 SUMO-protein ligase PIAS1 OS=Mus musculus OX=10090 GN=Pias1 PE=1 SV=2)

HSP 1 Score: 119.398 bits (298), Expect = 1.811e-26
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--TYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGSWAP-MRSKKEVQEVTASYNGV 432

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BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Match: sp|O75925|PIAS1_HUMAN (E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2)

HSP 1 Score: 119.013 bits (297), Expect = 2.865e-26
Identity = 87/314 (27.71%), Postives = 146/314 (46.50%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDI 1021
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    +LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++ +   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL        D + F + G W P  ++     +  +SYN +
Sbjct:  142 PFYDLLDELIKPTSLASDN-------SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR--NYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILK--YCTDCDEIQFKEDGTWAP-MRSKKEVQEVSASYNGV 432

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Match: A0A0X3PN85 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR123421 PE=4 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 1.847e-42
Identity = 105/321 (32.71%), Postives = 168/321 (52.34%), Query Frame = 2

Query:   74 FVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK---FDIRAIIRFSNIEDVHKVDDQF-------------TLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEH----SNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNK 976
            F  +PF++ I+ I P T L  + L  +  PG+    + L   + +D +  ++   +   +K   F ++ I+RF+ ++    V+ +                 D FPIHL L++N     LP  LP  R G DGRR  RPV+++  L  +P V N   + W  D      F++AVYL R+R+  EL + L +        T+  I E     + + NT +D DL +++NT+   L+CP+S+ R+  PVRG +C H+QC+D  TYL++N  KP W+CPVCD    F  L VD L+L IL D  +++++ ++F +   W P  K
Sbjct:  115 FTSSPFFKVIEVIRPPTILSPSEL--NFIPGKRPYERALNLRISIDQAEAITYHSQRLDDKRLDFGVQVIMRFAKLDPADLVNLRIGEPKQQQQQLSLSPQPDNFPIHLMLHVNGRPAQLPPLLPTTRPGLDGRRNARPVNITPLLRVSPAVSNTVKLVWTHDYATYSYFFYAVYLARKRSTRELCEALRRHSFQTASVTKQKIIEKLASTAASTNTMEDADL-VIENTLPVQLLCPLSKCRIDLPVRGHNCQHIQCYDANTYLLINERKPAWKCPVCDVPAPFHELLVDGLMLEILADTMTENLEEIVFKEDSSWSPVGK 432

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Match: A0A0V0J591 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR123421 PE=4 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 5.377e-42
Identity = 105/321 (32.71%), Postives = 168/321 (52.34%), Query Frame = 2

Query:   74 FVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK---FDIRAIIRFSNIEDVHKVDDQF-------------TLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFI----AEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNK 976
            F  +PF++ I+ I P T L  + L  +  PG+    + L   + +D +  ++   +   +K   F ++ I+RF+ ++    V+ +                 D FPIHL L++N     LP  LP  R G DGRR  RPV+++  L  +P V N   + W  D      F++AVYL R+R+  EL + L +        T+  I    A  + + NT +D DL +++NT+   L+CP+S+ R+  PVRG +C H+QC+D  TYL++N  KP W+CPVCD    F  L VD L+L IL D  +++++ ++F +   W P  K
Sbjct:  115 FTSSPFFKVIEVIRPPTILSPSEL--NFIPGKRPYERALNLRISIDQAEAITYHSQRLDDKRLDFGVQVIMRFAKLDPADLVNLRIGEPKQQQQQLSLSPQPDNFPIHLMLHVNGRPAQLPPLLPTTRPGLDGRRNARPVNITPLLRVSPAVSNTVKLVWTHDYATYSYFFYAVYLARKRSTRELCEALRRHSFQTASVTKQKIIEKLASTAASTNTMEDADL-VIENTLPVQLLCPLSKCRIDLPVRGHNCQHIQCYDANTYLLINERKPAWKCPVCDVPAPFHELLVDGLMLEILADTMTENLEEIVFKEDSSWSPVGK 432

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Match: A0A0X3PH50 (E3 SUMO-protein ligase PIAS1 (Fragment) OS=Schistocephalus solidus OX=70667 GN=PIAS1 PE=4 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 6.145e-42
Identity = 105/321 (32.71%), Postives = 168/321 (52.34%), Query Frame = 2

Query:   74 FVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK---FDIRAIIRFSNIEDVHKVDDQF-------------TLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEH----SNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNK 976
            F  +PF++ I+ I P T L  + L  +  PG+    + L   + +D +  ++   +   +K   F ++ I+RF+ ++    V+ +                 D FPIHL L++N     LP  LP  R G DGRR  RPV+++  L  +P V N   + W  D      F++AVYL R+R+  EL + L +        T+  I E     + + NT +D DL +++NT+   L+CP+S+ R+  PVRG +C H+QC+D  TYL++N  KP W+CPVCD    F  L VD L+L IL D  +++++ ++F +   W P  K
Sbjct:  191 FTSSPFFKVIEVIRPPTILSPSEL--NFIPGKRPYERALNLRISIDQAEAITYHSQRLDDKRLDFGVQVIMRFAKLDPADLVNLRIGEPKQQQQQLSLSPQPDNFPIHLMLHVNGRPAQLPPLLPTTRPGLDGRRNARPVNITPLLRVSPAVSNTVKLVWTHDYATYSYFFYAVYLARKRSTRELCEALRRHSFQTASVTKQKIIEKLASTAASTNTMEDADL-VIENTLPVQLLCPLSKCRIDLPVRGHNCQHIQCYDANTYLLINERKPAWKCPVCDVPAPFHELLVDGLMLEILADTMTENLEEIVFKEDSSWSPVGK 508

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Match: A0A0X3PX66 (E3 SUMO-protein ligase PIAS1 (Fragment) OS=Schistocephalus solidus OX=70667 GN=PIAS1 PE=4 SV=1)

HSP 1 Score: 177.178 bits (448), Expect = 9.579e-42
Identity = 105/321 (32.71%), Postives = 168/321 (52.34%), Query Frame = 2

Query:   74 FVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK---FDIRAIIRFSNIEDVHKVDDQF-------------TLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFI----AEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNK 976
            F  +PF++ I+ I P T L  + L  +  PG+    + L   + +D +  ++   +   +K   F ++ I+RF+ ++    V+ +                 D FPIHL L++N     LP  LP  R G DGRR  RPV+++  L  +P V N   + W  D      F++AVYL R+R+  EL + L +        T+  I    A  + + NT +D DL +++NT+   L+CP+S+ R+  PVRG +C H+QC+D  TYL++N  KP W+CPVCD    F  L VD L+L IL D  +++++ ++F +   W P  K
Sbjct:  191 FTSSPFFKVIEVIRPPTILSPSEL--NFIPGKRPYERALNLRISIDQAEAITYHSQRLDDKRLDFGVQVIMRFAKLDPADLVNLRIGEPKQQQQQLSLSPQPDNFPIHLMLHVNGRPAQLPPLLPTTRPGLDGRRNARPVNITPLLRVSPAVSNTVKLVWTHDYATYSYFFYAVYLARKRSTRELCEALRRHSFQTASVTKQKIIEKLASTAASTNTMEDADL-VIENTLPVQLLCPLSKCRIDLPVRGHNCQHIQCYDANTYLLINERKPAWKCPVCDVPAPFHELLVDGLMLEILADTMTENLEEIVFKEDSSWSPVGK 508

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Match: A0A0R3SHI3 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS4396 PE=4 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 7.359e-41
Identity = 108/311 (34.73%), Postives = 169/311 (54.34%), Query Frame = 2

Query:   71 RFVLTPFYECIDTIIPLTKLRLTNLLPDV--KPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIED--VHKV-DDQFTL---KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNT-QNFIAEHSNNH---NTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQW 961
            RF  TPFYE +D I P T +    + PDV    G+    +  +  L  + S  ++    +  N+  F ++A++RF  +E   +H++   Q TL   +D  PIHL + +N   + LP FLP  R   DGRR  RP+ ++  L   P  +N   + W  D      ++FAVYLV+R + +EL   L      P     +  IA+ +++    N G+DDD + + NT+   L+CP+S+ R++ PVRG+ C H+QC+D  TY I+N  KP W+CPVCD    F  L VD L++ IL   +S++ + ++FN+ G W
Sbjct:  173 RFSDTPFYEILDVIQPPTLI----IPPDVNFHTGKRPYERTYDIKLDANQSETITYHSYNVGNRREFRVQALVRFGKLEPSMLHRITASQPTLEPFQDNMPIHLAVQVNQRNVILPPFLPTSRPNMDGRRNARPISITPQLRMCPGAVNLIKLSWSHDYTSFTYYFFAVYLVKRLSTKELCDFLKTNCYRPGNFVRKQIIAKLASSGLPLNDGEDDDDIQIQNTLPVQLLCPLSKCRINLPVRGKRCQHIQCYDADTYFIINERKPAWKCPVCDLLAPFDELFVDGLLMEILESKKSQNAEEIVFNEDGSW 479

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Match: pias1a (protein inhibitor of activated STAT, 1a [Source:ZFIN;Acc:ZDB-GENE-120727-5])

HSP 1 Score: 123.25 bits (308), Expect = 1.414e-28
Identity = 87/296 (29.39%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLV+++T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  145 PFYDVLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISGSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVKQQTSTALLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRAVTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS--CVDCDEIQFKEDGSWAP 418

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Match: pias1b (protein inhibitor of activated STAT, 1b [Source:ZFIN;Acc:ZDB-GENE-050419-202])

HSP 1 Score: 122.094 bits (305), Expect = 2.429e-28
Identity = 87/296 (29.39%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  139 PFYDTLDELIKPTSLASDN-------NQRFQETCFAFALTPQQVQQISSSMDISGTKCDFAVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS--CVDCDEIQFKEDGNWAP 412

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Match: pias1a (protein inhibitor of activated STAT, 1a [Source:ZFIN;Acc:ZDB-GENE-120727-5])

HSP 1 Score: 122.094 bits (305), Expect = 2.549e-28
Identity = 87/296 (29.39%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLV+++T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  131 PFYDVLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISGSMDISGTKCDFTVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVKQQTSTALLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRAVTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS--CVDCDEIQFKEDGSWAP 404

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Match: pias1b (protein inhibitor of activated STAT, 1b [Source:ZFIN;Acc:ZDB-GENE-050419-202])

HSP 1 Score: 122.094 bits (305), Expect = 3.082e-28
Identity = 87/296 (29.39%), Postives = 138/296 (46.62%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  136 PFYDTLDELIKPTSLASDN-------NQRFQETCFAFALTPQQVQQISSSMDISGTKCDFAVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS--CVDCDEIQFKEDGNWAP 409

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Match: pias1b (protein inhibitor of activated STAT, 1b [Source:ZFIN;Acc:ZDB-GENE-050419-202])

HSP 1 Score: 119.013 bits (297), Expect = 8.705e-28
Identity = 64/194 (32.99%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  S+  AVYLVR+++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  199 PGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SYSMAVYLVRQQSSSVLLQRLRSKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNS--CVDCDEIQFKEDGNWAP 383

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006097.1 (pep scaffold:Pmarinus_7.0:GL477570:42904:66158:-1 gene:ENSPMAG00000005462.1 transcript:ENSPMAT00000006097.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 118.242 bits (295), Expect = 3.987e-28
Identity = 69/213 (32.39%), Postives = 112/213 (52.58%), Query Frame = 2

Query:  329 KDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            +D FP +L + +N  L  LP +LP  + G + +R  RP++++  +  +P V N   + W  D  +  ++  +VYLV++ T   L   +  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   CTHLQCFD   Y+ MN  KPTW CPVCDKK  +  L +D L + IL+      +D + F + G W P
Sbjct:  233 EDHFPANLCVKVNGKLCPLPGYLPPTKNGVEPKRPSRPINITAYVRLSPTVPNHITVSWTADFGR--NYSISVYLVKQLTSSLLLNRMKAKGIRNSDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCTHLQCFDAALYIQMNEKKPTWVCPVCDKKAPYDSLIIDGLFMEILSS--CTDVDEIKFREDGSWSP 436

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001340.1 (pep scaffold:Pmarinus_7.0:GL476352:326724:335624:-1 gene:ENSPMAG00000001204.1 transcript:ENSPMAT00000001340.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 109.768 bits (273), Expect = 1.963e-25
Identity = 63/187 (33.69%), Postives = 94/187 (50.27%), Query Frame = 2

Query:  407 RTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            + G + +R  R V+++  +   P V N   + W  D  +  S+  AV+LV++ +   L   L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+S P R   CTHLQCFD   YL MN  KPTW CPVCDKK  +  L +D L + ILN       D + F + G W P
Sbjct:  240 KNGVEPKRSSRAVNMTSLVRLTPSVPNHITVSWSTDFGR--SYSLAVHLVKQLSSAVLLNRLKAKGIRNSDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLSLPCRALTCTHLQCFDAALYLQMNEKKPTWVCPVCDKKAPYDGLIIDGLFVEILNSC--TDADEIQFRQDGLWSP 417

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BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Yeast
Match: NFI1 (SUMO E3 ligase; catalyzes sumoylation of Yku70p/80p and Sir4p promoting telomere anchoring to the nuclear envelope and regulating telomerase activity; DNA-bound form catalyzes a DNA-damaged triggered sumoylation wave resulting in multisite modification of several DNA repair proteins, enhancing interactions between these proteins and accelerating repair; sumoylates Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; role in telomere length maintenance [Source:SGD;Acc:S000005682])

HSP 1 Score: 77.7962 bits (190), Expect = 4.124e-15
Identity = 44/157 (28.03%), Postives = 77/157 (49.04%), Query Frame = 2

Query:  527 ESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTND 997
            + +  + ++V   + E L   ++K+     Q T  +I    N     QDDD ++  +T+  SL CP+S  RM  P +   C H+QCFD + +L      PTWQCP+C     F  L++   +  I+ +  ++ ++ V  +  G WKP + +  +  D
Sbjct:  279 KEYSISCFIVEVFSPEALLGKILKRPKIIKQATTAYIKRTLNE----QDDDDIITTSTV-LSLQCPISCTRMKYPAKTDQCKHIQCFDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNC-NEDVEQVEISVDGSWKPIHNSSAVITD 429

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BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Yeast
Match: SIZ1 (SUMO E3 ligase; promotes attachment of small ubiquitin-related modifier sumo (Smt3p) to primarily cytoplasmic proteins; regulates Rsp5p ubiquitin ligase activity and is in turn itself regulated by Rsp5p; required for sumoylation of septins and histone H3 variant Cse4p, a prerequisite for STUbL-mediated Ub-dependent degradation; localizes to the septin ring; acts as an adapter between E2, Ubc9p and substrates; tends to compensate for survival of DNA damage in absence of Nfi1p [Source:SGD;Acc:S000002817])

HSP 1 Score: 72.7886 bits (177), Expect = 1.543e-13
Identity = 33/98 (33.67%), Postives = 51/98 (52.04%), Query Frame = 2

Query:  668 QDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQW 961
            +D+++ L   +   SL CP+S  RM  P +  +C HLQCFD + +L      PTWQCPVC        L +   +  IL + + K+++ V     G+W
Sbjct:  344 EDEEMGLTTTSTIMSLQCPISYTRMKYPSKSINCKHLQCFDALWFLHSQLQIPTWQCPVCQIDIALENLAISEFVDDILQNCQ-KNVEQVELTSDGKW 440

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Nematostella
Match: EDO32140 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SVX5])

HSP 1 Score: 95.1301 bits (235), Expect = 6.838e-21
Identity = 83/303 (27.39%), Postives = 139/303 (45.87%), Query Frame = 2

Query:   68 ARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKK---HKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
             R V  PF+E ID ++     R T+L+P V   +   N ++ F L      L++ S+    H  + F ++  +R   +E   +  D F      P  L + +N  + +LP ++P +    D +R  RPV+++     +  V N   + W     ++      +  +   +C  L Q L  +      +++  I E         D D  +   ++  +L+CP+ + +M+ P R   C+HLQCFD   YL MN  K TW CPVCD+K  F  L +D L   IL++  S S   + F + G W+P
Sbjct:   94 VRLVSLPFFEHIDDLV-----RPTSLVP-VGMSQLQENYVV-FHLTPRQVGLITTSRDNRPHSRHDFTVQIQLRICLLETSCEQSDNF------PSSLCIKVNGKICSLPGYVPPN-ASVDHKRPGRPVNITNQCRLSSTVPNHIHVSWTPRHGQRHVVVIRLVRLVTSSC--LMQRLKARGYRNPDHSRALIKE-----KLAHDPDSEVATTSLRVTLLCPLGKSKMTLPCRSVTCSHLQCFDAALYLQMNEKKTTWICPVCDQKAEFKSLVLDGLFREILDNT-SGSCTEISFYEDGSWRP 374

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Nematostella
Match: EDO40709 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6F2])

HSP 1 Score: 72.4034 bits (176), Expect = 1.727e-14
Identity = 39/111 (35.14%), Postives = 59/111 (53.15%), Query Frame = 2

Query:  530 SFYFAVYLVRRRTCEELSQILMKKQLSPIQNT-----QNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVC 847
            S  F + LV R +   + Q L++K+L P ++      +NF    +     G DD +      I  SL CP++  R+S P RG  C H+QCFD  +YL +N  + +W+CPVC
Sbjct:   88 SHLFVLQLVHRPSVSSVLQSLLRKRLLPAEHCITKVKRNFSLCSTAPTTNGSDDGVE--QTAIKVSLKCPITFRRISLPARGHDCKHIQCFDLESYLRLNCERGSWKCPVC 196

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Match: pias1b (E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc:101160651])

HSP 1 Score: 125.176 bits (313), Expect = 3.535e-29
Identity = 95/330 (28.79%), Postives = 155/330 (46.97%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDISNYPNAINDVDSTKSN 1069
            PFY+ +D +I  T L   N        RF       F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  SF  AVYLVR+++   L Q L  K +    +++  I E         D +  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL+       D + F + G W P  ++     +  +SYN +       +DV  T++N
Sbjct:  129 PFYDVLDELIKPTSLVSDNT------QRF-QEACYAFALTPQQVQQISSSMDISGTKCDFAVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SFSMAVYLVRQQSSAVLLQRLRAKGIRNPDHSRALIKE-----KLTADPESEIATTSLRVSLLCPLGKMRLTIPCRSATCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILSS--CSDCDEIQFKEDGSWAP-MRSKKEVQEVSASYNGVD------SDVSRTEAN 429

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Match: pias1b (E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc:101160651])

HSP 1 Score: 124.02 bits (310), Expect = 7.622e-29
Identity = 92/323 (28.48%), Postives = 151/323 (46.75%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDISNYPNAIND 1048
            PFY+ +D +I  T L   N        RF       F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N     LP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  SF  AVYLVR+++   L Q L  K +    +++  I E         D +  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + IL+       D + F + G W P  ++     +  +SYN + +     N+
Sbjct:  138 PFYDVLDELIKPTSLVSDNT------QRF-QEACYAFALTPQQVQQISSSMDISGTKCDFAVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--SFSMAVYLVRQQSSAVLLQRLRAKGIRNPDHSRALIKE-----KLTADPESEIATTSLRVSLLCPLGKMRLTIPCRSATCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILSS--CSDCDEIQFKEDGSWAP-MRSKKEVQEVSASYNGVDSGTTEANE 437

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Match: pias2 (E3 SUMO-protein ligase PIAS2 [Source:NCBI gene;Acc:101155036])

HSP 1 Score: 119.013 bits (297), Expect = 1.412e-27
Identity = 67/194 (34.54%), Postives = 102/194 (52.58%), Query Frame = 2

Query:  386 PQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            P F P  + G + +R  RP++++  +  +  V N+  + W  +  K  ++  +VYLVR+ T   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R++ P R   C+HLQCFD   YL MN  KPTW CPVCDKK  +  L +D L L ILND     +D + F + G W P
Sbjct:  151 PGFAPPPKNGVEPKRPGRPLNITSLVRLSSAVPNQISVTWAPEIGK--TYSMSVYLVRQLTSPLLLQRLKMKGIRNPDHSRALIKE-----KLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRAVTCSHLQCFDAALYLQMNEKKPTWICPVCDKKAAYENLIIDGLFLEILND--CSDVDEIKFLEGGTWCP 335

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Match: pias1a (E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc:101169428])

HSP 1 Score: 119.013 bits (297), Expect = 1.714e-27
Identity = 86/296 (29.05%), Postives = 139/296 (46.96%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    TLP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  155 PFYDMLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFSVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCTLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--NYSMAVYLVKQQSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFVEILNS--CMDCDEIQFKEDGSWAP 428

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Match: pias1a (E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc:101169428])

HSP 1 Score: 119.783 bits (299), Expect = 1.922e-27
Identity = 86/296 (29.05%), Postives = 139/296 (46.96%), Query Frame = 2

Query:   86 PFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNK--FDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKP 967
            PFY+ +D +I  T L   N        +        F+L       +S S      K  F ++  +RF   E     +D F      P +L + +N    TLP +LP  + G + +R  RP++++  +  +  V N  ++ W  +  +  ++  AVYLV++++   L Q L  K +    +++  I E         D D  +   ++  SL+CP+ ++R+  P R   C+HLQCFD   Y+ MN  KPTW CPVCDKK  + +L +D L + ILN       D + F + G W P
Sbjct:  152 PFYDMLDELIKPTSLASDN-------SQRFQETCFAFALTPQQVQQISSSMDISGTKCDFSVQVQLRFCLSETSCPQEDHF------PPNLCVKVNGKPCTLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTSEIGR--NYSMAVYLVKQQSSTVLLQRLRAKGIRNPDHSRALIKE-----KLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFVEILNSCM--DCDEIQFKEDGSWAP 425

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Match: SMESG000058500.1 (SMESG000058500.1)

HSP 1 Score: 1478.38 bits (3826), Expect = 0.000e+0
Identity = 796/803 (99.13%), Postives = 796/803 (99.13%), Query Frame = 2

Query:   59 METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDISNYPNAINDVDSTKSNLTLRSEPFTMFNEEKYLQRILQNSNRMSLLARFRHPNSINNMFPATPKTTVPNCVPIVNPTFPDSLNRNVFNSPSNQQPHSLFNTAGAFQDNIRHISTMNLNPNHPNIPIRYKIGIKTSDQLSNYLINNRVNQLHNQKSKLNSYLGDGNSQIKITNVTSMAKNQNESSVIVISDDENDDVIPSSSDKESMVKMFARGRQMSHKRXXXXXXXXXXXGSAKSQKLSDNYGNQIPLRAYAASAPSVLNSQRIECCCTSNNMCAPHREILLRNKMSIINETGIVRDSNSLKLHEIVDLTQTNLQMENYQRSIRXXXXXXXXXXXXXXXXXXXXYEQQTHVKTNNLSKIHNPQSMEFTHQNPSTVKEFLKSLQNPGEKPCXXXXXXXXXXXXXXTQFTIQHRPVEQQAACQMSPEYVHQQWLNXXXXXXXXXXYPIPQNLLHTSPPFLQNSSVPQKNLSSLVNQSNGFFNC 2467
            METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHLKLNLNNTLITLPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDISNYPNAINDVDSTKSNLTLRSEPFTMFNEEKYLQRILQNSNRMSLLARFRHPNSINNMFPATPKTTVPNCVPIVNPTFPDSLNRNVFNSPSNQQPHSLFNTAGAFQDNIRHISTMNLNPNHPNIPIRYKIGIKTSDQLSNYLINNRVNQLHNQKSKLNSYLGDGNSQIKITNVTSMAKNQNESSVIVISDDENDDVIPSSSDKESMVKMFAR     HKRPTTVSSVPSTVGSAKSQKLSDNYGNQIPLRAYAASAPSVLNSQRIECCCTSNNMCAPHREILLRNKMSIINETGIVRDSNSLKLHEIVDLTQTNLQMENYQRSIRNINSNTVSLNNN NNNNNTSYEQQ HVKTNNLSKIHNPQSMEFTHQNPSTVKEFLKSLQNPGEKPCNDNNNANRMRNLLNTQFTIQHRPVEQQAACQMSPEYVHQQWLNMMMSSSQQQQYPIPQNLLHTSPPFLQNSSVPQKNLSSLVNQSNGFFNC
Sbjct:    1 METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHLKLNLNNTLITLPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDNKTPGMTNDDESSYNDISNYPNAINDVDSTKSNLTLRSEPFTMFNEEKYLQRILQNSNRMSLLARFRHPNSINNMFPATPKTTVPNCVPIVNPTFPDSLNRNVFNSPSNQQPHSLFNTAGAFQDNIRHISTMNLNPNHPNIPIRYKIGIKTSDQLSNYLINNRVNQLHNQKSKLNSYLGDGNSQIKITNVTSMAKNQNESSVIVISDDENDDVIPSSSDKESMVKMFARA----HKRPTTVSSVPSTVGSAKSQKLSDNYGNQIPLRAYAASAPSVLNSQRIECCCTSNNMCAPHREILLRNKMSIINETGIVRDSNSLKLHEIVDLTQTNLQMENYQRSIRNINSNTVSLNNNVNNNNNTSYEQQAHVKTNNLSKIHNPQSMEFTHQNPSTVKEFLKSLQNPGEKPCNDNNNANRMRNLLNTQFTIQHRPVEQQAACQMSPEYVHQQWLNMMMSSSQQQQYPIPQNLLHTSPPFLQNSSVPQKNLSSLVNQSNGFFNC 799

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Match: SMESG000069251.1 (SMESG000069251.1)

HSP 1 Score: 228.024 bits (580), Expect = 6.096e-65
Identity = 132/309 (42.72%), Postives = 188/309 (60.84%), Query Frame = 2

Query:   59 METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQ---FTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTI-NTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDN 973
            ME     L PFYE + TI+  T L L       K   F G+ + +F+L  D   LLSES+  KS K D+R IIRF  I +V  VD +    +++D FP HL + ++   ITL ++LP D   +DGRR  R +D+++ ++D   + ++ +IQWVQDDC  ESF +++YLVRRR+   LS  L + Q   I+ T +   E     ++ +D + M+    + N SLICP+S  R+ TP RG  CTHLQCFD  T+L+MNF KPTW CP+CD+  +F  LE+D LIL ILN+ RS+SI  + FN+ G WK ++
Sbjct:    1 MEIDNCTLAPFYEHMQTILNSTPLDLNIKKSSKKRLDFKGSHIFDFTLNFDTIKLLSESRT-KSIKLDVRFIIRFCKIINV--VDSEGKNLSMRDAFPQHLTIYIDGKPITLSKYLPYDSDRRDGRRNARLIDVTDAVVDAKSLQHQIIIQWVQDDCH-ESFSYSLYLVRRRSLHNLSYSLTRSQTCSIKRTASLFRERIYYPSSNKDIEYMVQTIIVKNASLICPISFCRIITPARGTLCTHLQCFDLDTFLLMNFMKPTWICPICDENLYFTCLEIDGLILSILNEKRSQSISEIKFNEEGHWKSND 305

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Match: SMESG000069251.1 (SMESG000069251.1)

HSP 1 Score: 228.794 bits (582), Expect = 4.209e-64
Identity = 132/309 (42.72%), Postives = 188/309 (60.84%), Query Frame = 2

Query:   59 METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQ---FTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTI-NTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDN 973
            ME     L PFYE + TI+  T L L       K   F G+ + +F+L  D   LLSES+  KS K D+R IIRF  I +V  VD +    +++D FP HL + ++   ITL ++LP D   +DGRR  R +D+++ ++D   + ++ +IQWVQDDC  ESF +++YLVRRR+   LS  L + Q   I+ T +   E     ++ +D + M+    + N SLICP+S  R+ TP RG  CTHLQCFD  T+L+MNF KPTW CP+CD+  +F  LE+D LIL ILN+ RS+SI  + FN+ G WK ++
Sbjct:    1 MEIDNCTLAPFYEHMQTILNSTPLDLNIKKSSKKRLDFKGSHIFDFTLNFDTIKLLSESRT-KSIKLDVRFIIRFCKIINV--VDSEGKNLSMRDAFPQHLTIYIDGKPITLSKYLPYDSDRRDGRRNARLIDVTDAVVDAKSLQHQIIIQWVQDDCH-ESFSYSLYLVRRRSLHNLSYSLTRSQTCSIKRTASLFRERIYYPSSNKDIEYMVQTIIVKNASLICPISFCRIITPARGTLCTHLQCFDLDTFLLMNFMKPTWICPICDENLYFTCLEIDGLILSILNEKRSQSISEIKFNEEGHWKSND 305

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Match: SMESG000069251.1 (SMESG000069251.1)

HSP 1 Score: 227.639 bits (579), Expect = 9.599e-62
Identity = 132/309 (42.72%), Postives = 188/309 (60.84%), Query Frame = 2

Query:   59 METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQ---FTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTI-NTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDN 973
            ME     L PFYE + TI+  T L L       K   F G+ + +F+L  D   LLSES+  KS K D+R IIRF  I +V  VD +    +++D FP HL + ++   ITL ++LP D   +DGRR  R +D+++ ++D   + ++ +IQWVQDDC  ESF +++YLVRRR+   LS  L + Q   I+ T +   E     ++ +D + M+    + N SLICP+S  R+ TP RG  CTHLQCFD  T+L+MNF KPTW CP+CD+  +F  LE+D LIL ILN+ RS+SI  + FN+ G WK ++
Sbjct:    1 MEIDNCTLAPFYEHMQTILNSTPLDLNIKKSSKKRLDFKGSHIFDFTLNFDTIKLLSESRT-KSIKLDVRFIIRFCKIINV--VDSEGKNLSMRDAFPQHLTIYIDGKPITLSKYLPYDSDRRDGRRNARLIDVTDAVVDAKSLQHQIIIQWVQDDCH-ESFSYSLYLVRRRSLHNLSYSLTRSQTCSIKRTASLFRERIYYPSSNKDIEYMVQTIIVKNASLICPISFCRIITPARGTLCTHLQCFDLDTFLLMNFMKPTWICPICDENLYFTCLEIDGLILSILNEKRSQSISEIKFNEEGHWKSND 305

[Close]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Match: SMESG000069251.1 (SMESG000069251.1)

HSP 1 Score: 215.698 bits (548), Expect = 1.193e-60
Identity = 119/272 (43.75%), Postives = 173/272 (63.60%), Query Frame = 2

Query:  170 FIGNQLLEFSLQLDHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQ---FTLKDVFPIHXXXXXXXXXXXXPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWVQDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNHNTGQDDDLMLVDNTI-NTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLIMNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQWKPDN 973
            F G+ + +F+L  D   LLSES+  KS K D+R IIRF  I +V  VD +    +++D FP HL + ++   ITL ++LP D   +DGRR  R +D+++ ++D   + ++ +IQWVQDDC  ESF +++YLVRRR+   LS  L + Q   I+ T +   E     ++ +D + M+    + N SLICP+S  R+ TP RG  CTHLQCFD  T+L+MNF KPTW CP+CD+  +F  LE+D LIL ILN+ RS+SI  + FN+ G WK ++
Sbjct:   24 FKGSHIFDFTLNFDTIKLLSESRT-KSIKLDVRFIIRFCKIINV--VDSEGKNLSMRDAFPQHLTIYIDGKPITLSKYLPYDSDRRDGRRNARLIDVTDAVVDAKSLQHQIIIQWVQDDCH-ESFSYSLYLVRRRSLHNLSYSLTRSQTCSIKRTASLFRERIYYPSSNKDIEYMVQTIIVKNASLICPISFCRIITPARGTLCTHLQCFDLDTFLLMNFMKPTWICPICDENLYFTCLEIDGLILSILNEKRSQSISEIKFNEEGHWKSND 291

The following BLAST results are available for this feature:

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Sea Lamprey
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Yeast
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Nematostella
BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
PIAS2	1.038e-27	34.54	protein inhibitor of activated STAT 2 [Source:HGNC...	[more]
PIAS2	1.361e-27	34.54	protein inhibitor of activated STAT 2 [Source:HGNC...	[more]
PIAS2	2.046e-27	34.54	protein inhibitor of activated STAT 2 [Source:HGNC...	[more]
PIAS1	5.967e-27	27.71	protein inhibitor of activated STAT 1 [Source:HGNC...	[more]
PIAS1	5.968e-27	27.71	protein inhibitor of activated STAT 1 [Source:HGNC...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gei-17	2.143e-22	27.97	E3 SUMO-protein ligase gei-17 [Source:UniProtKB/S...	[more]
gei-17	2.143e-22	27.97	E3 SUMO-protein ligase gei-17 [Source:UniProtKB/S...	[more]
gei-17	3.355e-22	28.72	E3 SUMO-protein ligase gei-17 [Source:UniProtKB/S...	[more]
gei-17	3.355e-22	28.72	E3 SUMO-protein ligase gei-17 [Source:UniProtKB/S...	[more]
gei-17	3.355e-22	28.72	E3 SUMO-protein ligase gei-17 [Source:UniProtKB/S...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Su(var)2-10	9.782e-31	33.07	gene:FBgn0003612 transcript:FBtr0343996	[more]
Su(var)2-10	1.065e-30	33.07	gene:FBgn0003612 transcript:FBtr0306705	[more]
Su(var)2-10	1.134e-30	33.07	gene:FBgn0003612 transcript:FBtr0088571	[more]
Su(var)2-10	1.156e-30	33.07	gene:FBgn0003612 transcript:FBtr0088570	[more]
Su(var)2-10	1.166e-30	33.07	gene:FBgn0003612 transcript:FBtr0088576	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pias1a	5.666e-28	28.66	protein inhibitor of activated STAT, 1a [Source:ZF...	[more]
pias1a	5.739e-28	28.66	protein inhibitor of activated STAT, 1a [Source:ZF...	[more]
pias1b	6.637e-28	29.05	protein inhibitor of activated STAT, 1b [Source:ZF...	[more]
BX890624.1	7.252e-28	29.05	protein inhibitor of activated STAT, 1b [Source:NC...	[more]
CR450724.1	7.252e-28	29.05	protein inhibitor of activated STAT, 1b [Source:NC...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mgc76132	6.248e-27	27.67	Ferritin, lower subunit (Ferritin L) [Source:Xenba...	[more]
PIAS1	7.076e-27	28.03	protein inhibitor of activated STAT 1 [Source:NCBI...	[more]
PIAS1	7.363e-27	28.03	protein inhibitor of activated STAT 1 [Source:NCBI...	[more]
mgc76132	7.366e-27	27.67	Ferritin, lower subunit (Ferritin L) [Source:Xenba...	[more]
PIAS1	7.614e-27	28.03	protein inhibitor of activated STAT 1 [Source:NCBI...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Pias2	8.778e-28	34.54	protein inhibitor of activated STAT 2 [Source:MGI ...	[more]
Pias2	1.590e-27	34.54	protein inhibitor of activated STAT 2 [Source:MGI ...	[more]
Pias2	1.598e-27	34.54	protein inhibitor of activated STAT 2 [Source:MGI ...	[more]
Pias1	2.589e-27	27.71	protein inhibitor of activated STAT 1 [Source:MGI ...	[more]
Pias1	4.497e-27	27.71	protein inhibitor of activated STAT 1 [Source:MGI ...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6AZ28\|PIAS2_RAT	5.755e-27	34.54	E3 SUMO-protein ligase PIAS2 OS=Rattus norvegicus ...	[more]
sp\|O75928\|PIAS2_HUMAN	9.825e-27	34.54	E3 SUMO-protein ligase PIAS2 OS=Homo sapiens OX=96...	[more]
sp\|Q8C5D8\|PIAS2_MOUSE	1.112e-26	34.54	E3 SUMO-protein ligase PIAS2 OS=Mus musculus OX=10...	[more]
sp\|O88907\|PIAS1_MOUSE	1.811e-26	27.71	E3 SUMO-protein ligase PIAS1 OS=Mus musculus OX=10...	[more]
sp\|O75925\|PIAS1_HUMAN	2.865e-26	27.71	E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=96...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0X3PN85	1.847e-42	32.71	Uncharacterized protein OS=Schistocephalus solidus...	[more]
A0A0V0J591	5.377e-42	32.71	Uncharacterized protein (Fragment) OS=Schistocepha...	[more]
A0A0X3PH50	6.145e-42	32.71	E3 SUMO-protein ligase PIAS1 (Fragment) OS=Schisto...	[more]
A0A0X3PX66	9.579e-42	32.71	E3 SUMO-protein ligase PIAS1 (Fragment) OS=Schisto...	[more]
A0A0R3SHI3	7.359e-41	34.73	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pias1a	1.414e-28	29.39	protein inhibitor of activated STAT, 1a [Source:ZF...	[more]
pias1b	2.429e-28	29.39	protein inhibitor of activated STAT, 1b [Source:ZF...	[more]
pias1a	2.549e-28	29.39	protein inhibitor of activated STAT, 1a [Source:ZF...	[more]
pias1b	3.082e-28	29.39	protein inhibitor of activated STAT, 1b [Source:ZF...	[more]
pias1b	8.705e-28	32.99	protein inhibitor of activated STAT, 1b [Source:ZF...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000006097.1	3.987e-28	32.39	pep scaffold:Pmarinus_7.0:GL477570:42904:66158:-1 ...	[more]
ENSPMAT00000001340.1	1.963e-25	33.69	pep scaffold:Pmarinus_7.0:GL476352:326724:335624:-...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
NFI1	4.124e-15	28.03	SUMO E3 ligase; catalyzes sumoylation of Yku70p/80...	[more]
SIZ1	1.543e-13	33.67	SUMO E3 ligase; promotes attachment of small ubiqu...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO32140	6.838e-21	27.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40709	1.727e-14	35.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pias1b	3.535e-29	28.79	E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc...	[more]
pias1b	7.622e-29	28.48	E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc...	[more]
pias2	1.412e-27	34.54	E3 SUMO-protein ligase PIAS2 [Source:NCBI gene;Acc...	[more]
pias1a	1.714e-27	29.05	E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc...	[more]
pias1a	1.922e-27	29.05	E3 SUMO-protein ligase PIAS1 [Source:NCBI gene;Acc...	[more]

BLAST of E3 SUMO-protein ligase PIAS1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000058500.1	0.000e+0	99.13	SMESG000058500.1	[more]
SMESG000069251.1	6.096e-65	42.72	SMESG000069251.1	[more]
SMESG000069251.1	4.209e-64	42.72	SMESG000069251.1	[more]
SMESG000069251.1	9.599e-62	42.72	SMESG000069251.1	[more]
SMESG000069251.1	1.193e-60	43.75	SMESG000069251.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001604 ID=SMED30001604|Name=E3 SUMO-protein ligase PIAS1|organism=Schmidtea mediterranea sexual|type=transcript|length=2598bp
CTATATAAATCTTATATGAAATAACGATTATAGAATATTTAATTTATTGT
CAAAAAACATGGAAACTGCTAGGTTCGTATTAACGCCATTTTACGAATGT
ATAGATACAATCATTCCTCTTACAAAACTACGACTAACAAATTTATTACC
CGACGTCAAGCCTGGAAGATTTATTGGTAATCAGTTGCTTGAGTTTTCTT
TGCAATTAGATCATAGCTTTTTGTTATCAGAATCAAAAAAACACAAGTCG
AATAAATTTGATATTCGTGCTATCATACGATTTTCTAACATCGAAGATGT
GCATAAAGTAGATGATCAATTTACATTGAAAGATGTCTTCCCTATTCATC
TTAAACTTAATTTAAACAATACTCTTATTACACTGCCACAATTTTTACCT
AATGATCGAACAGGTAAAGACGGTAGGCGGTTTCCTCGACCTGTAGATTT
ATCAGAAGGATTACTTGACAATCCCTTAGTAATTAACAAGTTTTTAATCC
AATGGGTTCAAGATGATTGTAAGAAAGAATCGTTTTATTTCGCTGTTTAT
TTAGTACGACGAAGGACTTGTGAAGAATTAAGCCAAATATTGATGAAAAA
ACAACTTTCTCCTATACAGAATACACAGAATTTCATTGCCGAACATAGTA
ATAACCACAACACTGGCCAAGATGATGATCTGATGTTAGTTGACAACACA
ATCAACACCTCTCTCATTTGTCCAGTTTCCCGTGTGAGAATGTCAACGCC
AGTTCGAGGTCAACACTGTACACATCTTCAGTGTTTTGATTGTGTAACTT
ATTTGATAATGAATTTTAACAAACCAACTTGGCAATGTCCTGTTTGTGAT
AAGAAAACGTTTTTCTGTTATTTAGAGGTTGATAGTTTGATACTCGGTAT
TCTGAACGATTTGCGGTCAAAGTCAATTGATGGAGTCATATTTAATAAAA
TCGGCCAATGGAAACCGGATAACAAAACGCCCGGAATGACCAATGACGAT
GAATCATCATACAATGATATATCGAATTATCCCAATGCCATCAACGATGT
CGATTCGACAAAATCTAATCTCACTCTGAGATCCGAACCATTTACTATGT
TTAATGAAGAAAAGTACCTACAACGGATTTTACAAAATTCTAACCGAATG
TCACTGTTGGCGAGATTCCGCCATCCCAACTCAATCAACAACATGTTCCC
TGCTACGCCAAAAACCACAGTTCCAAATTGTGTACCGATTGTGAATCCGA
CATTTCCAGATTCACTTAATCGAAATGTTTTTAATTCTCCATCTAATCAA
CAGCCACATTCATTATTCAATACCGCAGGTGCTTTCCAAGATAATATTCG
CCATATTTCAACAATGAATCTCAATCCCAATCATCCCAATATTCCGATAA
GATATAAGATTGGAATAAAGACATCCGATCAATTATCGAATTACTTGATC
AATAATCGAGTCAATCAATTACACAATCAAAAATCGAAACTGAATTCTTA
TTTGGGCGATGGCAATTCTCAGATCAAGATCACCAATGTCACATCAATGG
CAAAAAATCAAAACGAATCAAGTGTGATAGTGATCTCCGATGATGAAAAT
GATGATGTTATTCCTTCTTCCTCAGATAAAGAATCAATGGTTAAAATGTT
TGCAAGAGGTAGGCAAATGTCTCATAAAAGACCAACAACTGTATCAAGTG
TTCCATCAACTGTCGGTTCAGCTAAGTCACAGAAACTATCAGACAACTAC
GGAAACCAAATACCGTTGCGAGCATATGCAGCCAGCGCACCTTCAGTATT
GAATTCACAACGCATTGAATGCTGCTGCACTTCTAATAACATGTGCGCTC
CTCATCGTGAAATTCTATTACGCAATAAAATGTCAATAATCAATGAGACT
GGCATTGTAAGAGACTCGAACTCATTAAAACTCCATGAAATAGTCGATCT
CACACAAACAAATCTCCAAATGGAGAATTACCAGAGATCTATAAGAAACA
TCAATAGTAACACTGTCAGTTTAAATAACAATGCAAATAACAATAACAAT
ACATCATATGAGCAACAGACACATGTAAAAACGAATAATCTATCAAAAAT
TCACAATCCACAGTCCATGGAATTTACACATCAAAATCCAAGCACTGTAA
AAGAATTCCTAAAATCCTTACAAAATCCCGGGGAAAAACCTTGCAACGAT
AACAATAATGCCAACCGAATGAGAAATTTATTAAATACTCAATTCACGAT
CCAGCACCGACCGGTGGAGCAGCAAGCCGCGTGTCAAATGTCTCCGGAAT
ATGTTCATCAACAGTGGCTAAATATGATGATGTCGTCTTCCCAGCAGCAG
CAATACCCGATTCCACAAAACCTGTTGCACACTTCTCCACCATTCCTCCA
AAACAGTTCTGTTCCGCAAAAAAATTTGAGTTCTCTCGTTAACCAATCCA
ACGGGTTTTTCAACTGCTGATTTAAGATTCTATAAAATAAAAATGATCCA
GTGTAAATATAACTGTAATTTATCTTTGATGATGATTATTATATGATTTG
TATTCGATCTGAATCCATTGTTTTCATACCGTTTTGTACTTGAGATCG

protein sequence of SMED30001604-orf-1

>SMED30001604-orf-1 ID=SMED30001604-orf-1|Name=SMED30001604-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=804bp
METARFVLTPFYECIDTIIPLTKLRLTNLLPDVKPGRFIGNQLLEFSLQL
DHSFLLSESKKHKSNKFDIRAIIRFSNIEDVHKVDDQFTLKDVFPIHLKL
NLNNTLITLPQFLPNDRTGKDGRRFPRPVDLSEGLLDNPLVINKFLIQWV
QDDCKKESFYFAVYLVRRRTCEELSQILMKKQLSPIQNTQNFIAEHSNNH
NTGQDDDLMLVDNTINTSLICPVSRVRMSTPVRGQHCTHLQCFDCVTYLI
MNFNKPTWQCPVCDKKTFFCYLEVDSLILGILNDLRSKSIDGVIFNKIGQ
WKPDNKTPGMTNDDESSYNDISNYPNAINDVDSTKSNLTLRSEPFTMFNE
EKYLQRILQNSNRMSLLARFRHPNSINNMFPATPKTTVPNCVPIVNPTFP
DSLNRNVFNSPSNQQPHSLFNTAGAFQDNIRHISTMNLNPNHPNIPIRYK
IGIKTSDQLSNYLINNRVNQLHNQKSKLNSYLGDGNSQIKITNVTSMAKN
QNESSVIVISDDENDDVIPSSSDKESMVKMFARGRQMSHKRPTTVSSVPS
TVGSAKSQKLSDNYGNQIPLRAYAASAPSVLNSQRIECCCTSNNMCAPHR
EILLRNKMSIINETGIVRDSNSLKLHEIVDLTQTNLQMENYQRSIRNINS
NTVSLNNNANNNNNTSYEQQTHVKTNNLSKIHNPQSMEFTHQNPSTVKEF
LKSLQNPGEKPCNDNNNANRMRNLLNTQFTIQHRPVEQQAACQMSPEYVH
QQWLNMMMSSSQQQQYPIPQNLLHTSPPFLQNSSVPQKNLSSLVNQSNGF
FNC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **INTERPRO**
Term	Definition
IPR038654	PINIT_sf
IPR004181	Znf_MIZ
IPR013083	Znf_RING/FYVE/PHD
IPR023321	PINIT

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0019789	SUMO transferase activity

Vocabulary: **biological process**
Term	Definition
GO:0016925	protein sumoylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 644..671
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 552..572
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 546..572
None	No IPR available	PANTHER	PTHR10782:SF72	SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I	coord: 18..646
None	No IPR available	PANTHER	PTHR10782	ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN	coord: 18..646
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 224..300
IPR038654	PINIT domain superfamily	GENE3D	G3DSA:2.60.120.780		coord: 16..181 e-value: 2.1E-21 score: 78.4
IPR004181	Zinc finger, MIZ-type	PFAM	PF02891	zf-MIZ	coord: 231..278 e-value: 3.0E-19 score: 68.5
IPR004181	Zinc finger, MIZ-type	PROSITE	PS51044	ZF_SP_RING	coord: 219..296 score: 34.694
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 183..317 e-value: 1.9E-31 score: 110.5
IPR023321	PINIT domain	PROSITE	PS51466	PINIT	coord: 6..182 score: 15.137