Spectrin alpha chain

Overview


Name	Spectrin alpha chain
Smed ID	SMED30001586
Length (bp)	899

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Spectrin alpha chain (SMED30001586) t-SNE clustered cells

Violin plots show distribution of expression levels for Spectrin alpha chain (SMED30001586) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001586

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30001586	SMESG000005289.1	Contig37746	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30001586	SMESG000005289.1	Contig37746	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
pharynx	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neuron	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
cholinergic neuron	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
glial cell	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
GABAergic neuron	SMED30001586	SMESG000005289.1	dd_Smed_v6_919_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30001586	SMESG000005289.1	dd_Smed_v4_919_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Spectrin alpha chain vs. Ensembl Human
Match: SPTAN1 (spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273])

HSP 1 Score: 85.5001 bits (210), Expect = 7.383e-20
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:   15 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 77

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Human
Match: SPTAN1 (spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273])

HSP 1 Score: 86.2705 bits (212), Expect = 5.128e-18
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65

HSP 2 Score: 51.6026 bits (122), Expect = 1.379e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Human
Match: SPTAN1 (spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273])

HSP 1 Score: 86.2705 bits (212), Expect = 5.129e-18
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65

HSP 2 Score: 51.6026 bits (122), Expect = 1.319e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

HSP 3 Score: 48.9062 bits (115), Expect = 9.667e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Human
Match: SPTAN1 (spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273])

HSP 1 Score: 86.2705 bits (212), Expect = 5.173e-18
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65

HSP 2 Score: 51.6026 bits (122), Expect = 1.354e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1501 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1553

HSP 3 Score: 48.9062 bits (115), Expect = 9.748e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Human
Match: SPTAN1 (spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273])

HSP 1 Score: 86.2705 bits (212), Expect = 5.181e-18
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65

HSP 2 Score: 51.6026 bits (122), Expect = 1.344e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

HSP 3 Score: 48.9062 bits (115), Expect = 9.587e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Celegans
Match: spc-1 (SPeCtrin [Source:UniProtKB/TrEMBL;Acc:G4S034])

HSP 1 Score: 83.5741 bits (205), Expect = 1.329e-17
Identity = 37/63 (58.73%), Postives = 53/63 (84.13%), Query Frame = 2

Query:   56 KEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            +EI+ILET +DI +RR++VL  YS FK+ ++ +R +LE+A+++QYFKRDADEL  WILEK+QT
Sbjct:   21 QEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 83

HSP 2 Score: 50.0618 bits (118), Expect = 1.447e-6
Identity = 22/51 (43.14%), Postives = 37/51 (72.55%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +  +R+Q+L+R++  KEA  ++R KL +++  Q F RDADE+E+W+ EK Q
Sbjct: 1479 VTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQ 1529

[Close]

Query:   56 KEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            +EI+ILET +DI +RR++VL  YS FK+ ++ +R +LE+A+++QYFKRDADEL  WILEK+QT
Sbjct:   21 QEIRILETADDIHQRRQEVLGHYSIFKDHSQTKRDRLEEARQFQYFKRDADELNVWILEKLQT 83

HSP 2 Score: 50.0618 bits (118), Expect = 1.460e-6
Identity = 22/51 (43.14%), Postives = 37/51 (72.55%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +  +R+Q+L+R++  KEA  ++R KL +++  Q F RDADE+E+W+ EK Q
Sbjct: 1484 VTRKRDQILDRWNGLKEALIQKRFKLGESQTLQQFSRDADEIENWMTEKFQ 1534

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Fly
Match: alpha-Spec (gene:FBgn0250789 transcript:FBtr0332879)

HSP 1 Score: 97.8265 bits (242), Expect = 2.734e-22
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PKE+KILET EDIQERREQVL+RY+ FK  T ++R+KLED++++QYFKRDADELESWI EK+Q 
Sbjct:    6 PKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQA 69

HSP 2 Score: 54.299 bits (129), Expect = 7.401e-8
Identity = 23/55 (41.82%), Postives = 39/55 (70.91%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
              +D+ +RR+ +L R +A +E + +RR+ LED+ +YQ F+RD DE + WI EK++
Sbjct:  543 AADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLK 597

HSP 3 Score: 52.7582 bits (125), Expect = 2.346e-7
Identity = 25/51 (49.02%), Postives = 35/51 (68.63%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            + E+R+QVL R+   KE   E+R +L D +  Q F RDADE+E+WI EK+Q
Sbjct: 1502 VDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQ 1552

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Fly
Match: alpha-Spec (gene:FBgn0250789 transcript:FBtr0332878)

HSP 1 Score: 97.8265 bits (242), Expect = 2.761e-22
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PKE+KILET EDIQERREQVL+RY+ FK  T ++R+KLED++++QYFKRDADELESWI EK+Q 
Sbjct:    6 PKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQA 69

HSP 2 Score: 54.299 bits (129), Expect = 7.337e-8
Identity = 23/55 (41.82%), Postives = 39/55 (70.91%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
              +D+ +RR+ +L R +A +E + +RR+ LED+ +YQ F+RD DE + WI EK++
Sbjct:  543 AADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLK 597

HSP 3 Score: 52.7582 bits (125), Expect = 2.410e-7
Identity = 25/51 (49.02%), Postives = 35/51 (68.63%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            + E+R+QVL R+   KE   E+R +L D +  Q F RDADE+E+WI EK+Q
Sbjct: 1502 VDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQ 1552

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Fly
Match: alpha-Spec (gene:FBgn0250789 transcript:FBtr0332880)

HSP 1 Score: 97.8265 bits (242), Expect = 2.783e-22
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PKE+KILET EDIQERREQVL+RY+ FK  T ++R+KLED++++QYFKRDADELESWI EK+Q 
Sbjct:    6 PKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQA 69

HSP 2 Score: 54.299 bits (129), Expect = 7.200e-8
Identity = 23/55 (41.82%), Postives = 39/55 (70.91%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
              +D+ +RR+ +L R +A +E + +RR+ LED+ +YQ F+RD DE + WI EK++
Sbjct:  543 AADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLK 597

HSP 3 Score: 52.7582 bits (125), Expect = 2.430e-7
Identity = 25/51 (49.02%), Postives = 35/51 (68.63%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            + E+R+QVL R+   KE   E+R +L D +  Q F RDADE+E+WI EK+Q
Sbjct: 1470 VDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQ 1520

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Fly
Match: alpha-Spec (gene:FBgn0250789 transcript:FBtr0072789)

HSP 1 Score: 97.8265 bits (242), Expect = 2.835e-22
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PKE+KILET EDIQERREQVL+RY+ FK  T ++R+KLED++++QYFKRDADELESWI EK+Q 
Sbjct:    6 PKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQA 69

HSP 2 Score: 54.299 bits (129), Expect = 7.595e-8
Identity = 23/55 (41.82%), Postives = 39/55 (70.91%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
              +D+ +RR+ +L R +A +E + +RR+ LED+ +YQ F+RD DE + WI EK++
Sbjct:  543 AADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLK 597

HSP 3 Score: 52.7582 bits (125), Expect = 2.517e-7
Identity = 25/51 (49.02%), Postives = 35/51 (68.63%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            + E+R+QVL R+   KE   E+R +L D +  Q F RDADE+E+WI EK+Q
Sbjct: 1470 VDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQ 1520

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Zebrafish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:ZFIN;Acc:ZDB-GENE-051113-60])

HSP 1 Score: 84.3445 bits (207), Expect = 1.296e-17
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSVVRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 50.0618 bits (118), Expect = 2.742e-6
Identity = 25/56 (44.64%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              +D+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  540 AKDDVATRRDALLSRRNALHERAQFRRAALEDSFHLQQFFRDSDELKSWINEKMKT 595

HSP 3 Score: 48.521 bits (114), Expect = 8.315e-6
Identity = 26/55 (47.27%), Postives = 37/55 (67.27%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I +RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1523 PE-IFKRRSEVLDRWLRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1576

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Match: sptan1 (spectrin, alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:100036647])

HSP 1 Score: 84.3445 bits (207), Expect = 1.605e-17
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETAEDIQERRQQVLDRYLRFKELSVLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 65

HSP 2 Score: 51.2174 bits (121), Expect = 1.481e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1519 DIASRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1571

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Match: sptan1 (spectrin, alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:100036647])

HSP 1 Score: 84.3445 bits (207), Expect = 1.635e-17
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETAEDIQERRQQVLDRYLRFKELSVLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 65

HSP 2 Score: 51.2174 bits (121), Expect = 1.455e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1520 DIASRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1572

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Match: sptan1 (spectrin, alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:100036647])

HSP 1 Score: 84.3445 bits (207), Expect = 1.649e-17
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETAEDIQERRQQVLDRYLRFKELSVLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 65

HSP 2 Score: 51.2174 bits (121), Expect = 1.480e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1519 DIASRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1571

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Match: sptan1 (spectrin, alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:100036647])

HSP 1 Score: 84.3445 bits (207), Expect = 1.651e-17
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:   10 VKVLETAEDIQERRQQVLDRYLRFKELSVLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 69

HSP 2 Score: 51.2174 bits (121), Expect = 1.494e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1523 DIASRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1575

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Match: sptan1 (spectrin, alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:100036647])

HSP 1 Score: 84.3445 bits (207), Expect = 1.682e-17
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETAEDIQERRQQVLDRYLRFKELSVLRRQKLEDSYRFQFFQRDADELEKWIQEKLQ 65

HSP 2 Score: 51.2174 bits (121), Expect = 1.522e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1513 DIASRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1565

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Match: Sptan1 (spectrin alpha, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98386])

HSP 1 Score: 85.8853 bits (211), Expect = 1.928e-19
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:   15 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 78

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Match: Sptan1 (spectrin alpha, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98386])

HSP 1 Score: 86.2705 bits (212), Expect = 3.119e-18
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 1.205e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1501 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1553

HSP 3 Score: 48.9062 bits (115), Expect = 6.074e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Match: Sptan1 (spectrin alpha, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98386])

HSP 1 Score: 86.2705 bits (212), Expect = 3.151e-18
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 1.205e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

HSP 3 Score: 48.9062 bits (115), Expect = 6.353e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Match: Sptan1 (spectrin alpha, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98386])

HSP 1 Score: 86.2705 bits (212), Expect = 3.177e-18
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 1.204e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

HSP 3 Score: 48.9062 bits (115), Expect = 6.462e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Match: Sptan1 (spectrin alpha, non-erythrocytic 1 [Source:MGI Symbol;Acc:MGI:98386])

HSP 1 Score: 86.2705 bits (212), Expect = 3.208e-18
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 1.194e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

HSP 3 Score: 48.9062 bits (115), Expect = 6.406e-6
Identity = 24/54 (44.44%), Postives = 36/54 (66.67%), Query Frame = 2

Query:   83 EDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            ED+  RR+ +L+R +A  E    RR +L D+   Q F RD+DEL+SW+ EK++T
Sbjct:  542 EDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKT 595

[Close]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Match: sp|P13395|SPTCA_DROME (Spectrin alpha chain OS=Drosophila melanogaster OX=7227 GN=alpha-Spec PE=1 SV=2)

HSP 1 Score: 97.8265 bits (242), Expect = 2.842e-21
Identity = 46/64 (71.88%), Postives = 57/64 (89.06%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PKE+KILET EDIQERREQVL+RY+ FK  T ++R+KLED++++QYFKRDADELESWI EK+Q 
Sbjct:    6 PKEVKILETVEDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQA 69

HSP 2 Score: 54.299 bits (129), Expect = 7.613e-7
Identity = 23/55 (41.82%), Postives = 39/55 (70.91%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
              +D+ +RR+ +L R +A +E + +RR+ LED+ +YQ F+RD DE + WI EK++
Sbjct:  543 AADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLK 597

HSP 3 Score: 52.7582 bits (125), Expect = 2.523e-6
Identity = 25/51 (49.02%), Postives = 35/51 (68.63%), Query Frame = 2

Query:   89 IQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            + E+R+QVL R+   KE   E+R +L D +  Q F RDADE+E+WI EK+Q
Sbjct: 1470 VDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQ 1520

[Close]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Match: sp|P16086|SPTN1_RAT (Spectrin alpha chain, non-erythrocytic 1 OS=Rattus norvegicus OX=10116 GN=Sptan1 PE=1 SV=2)

HSP 1 Score: 86.2705 bits (212), Expect = 2.223e-17
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 8.350e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

[Close]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Match: sp|P16546|SPTN1_MOUSE (Spectrin alpha chain, non-erythrocytic 1 OS=Mus musculus OX=10090 GN=Sptan1 PE=1 SV=4)

HSP 1 Score: 86.2705 bits (212), Expect = 2.223e-17
Identity = 39/64 (60.94%), Postives = 52/64 (81.25%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q 
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQV 66

HSP 2 Score: 51.2174 bits (121), Expect = 8.425e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

[Close]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Match: sp|P07751|SPTN1_CHICK (Spectrin alpha chain, non-erythrocytic 1 OS=Gallus gallus OX=9031 GN=SPTAN1 PE=1 SV=3)

HSP 1 Score: 86.2705 bits (212), Expect = 2.286e-17
Identity = 39/63 (61.90%), Postives = 51/63 (80.95%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADEL  WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSSLRRQKLEDSYRFQFFQRDADELGKWIQEKLQ 65

[Close]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Match: sp|Q13813|SPTN1_HUMAN (Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3)

HSP 1 Score: 86.2705 bits (212), Expect = 2.463e-17
Identity = 39/63 (61.90%), Postives = 52/63 (82.54%), Query Frame = 2

Query:   53 PKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            P  +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDA+ELE WI EK+Q
Sbjct:    3 PSGVKVLETAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQ 65

HSP 2 Score: 51.6026 bits (122), Expect = 6.624e-6
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1521 DISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1573

[Close]

BLAST of Spectrin alpha chain vs. TrEMBL
Match: A0A4E0R0S1 (Spna2 protein OS=Fasciola hepatica OX=6192 GN=D915_009742 PE=4 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 4.596e-27
Identity = 53/65 (81.54%), Postives = 60/65 (92.31%), Query Frame = 2

Query:   50 LPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            LP ++KILETPEDIQERREQVL+RYSAFKEATE RR +LE AK+YQ+FKRDADELE WILEK+QT
Sbjct:    4 LPTKVKILETPEDIQERREQVLSRYSAFKEATEFRRHRLEQAKRYQFFKRDADELEGWILEKLQT 68

[Close]

BLAST of Spectrin alpha chain vs. TrEMBL
Match: A0A5J4P2W7 (Spectrin alpha OS=Paragonimus westermani OX=34504 GN=DEA37_0010677 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 7.960e-25
Identity = 56/65 (86.15%), Postives = 61/65 (93.85%), Query Frame = 2

Query:   50 LPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            LP ++KILETPEDIQERREQVL+RYSAFKEATE RR KLE AK+YQYFKRDADELESWILEK+QT
Sbjct:    4 LPLKVKILETPEDIQERREQVLSRYSAFKEATEYRRYKLEQAKRYQYFKRDADELESWILEKLQT 68

[Close]

BLAST of Spectrin alpha chain vs. TrEMBL
Match: A0A4S2M595 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003879 PE=4 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.366e-24
Identity = 55/65 (84.62%), Postives = 61/65 (93.85%), Query Frame = 2

Query:   50 LPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            LP ++KILETPEDIQERREQVL+RYSAFKEATE RR +LE AK+YQYFKRDADELESWILEK+QT
Sbjct:    4 LPIKVKILETPEDIQERREQVLSRYSAFKEATEYRRHRLEQAKRYQYFKRDADELESWILEKLQT 68

[Close]

BLAST of Spectrin alpha chain vs. TrEMBL
Match: A0A419PZF6 (Spectrin alpha chain OS=Clonorchis sinensis OX=79923 GN=alpha-Spec PE=4 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.379e-24
Identity = 55/65 (84.62%), Postives = 61/65 (93.85%), Query Frame = 2

Query:   50 LPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            LP ++KILETPEDIQERREQVL+RYSAFKEATE RR +LE AK+YQYFKRDADELESWILEK+QT
Sbjct:    4 LPIKVKILETPEDIQERREQVLSRYSAFKEATEYRRHRLEQAKRYQYFKRDADELESWILEKLQT 68

[Close]

BLAST of Spectrin alpha chain vs. TrEMBL
Match: A0A075AI56 (Spectrin repeat-containing domain protein OS=Opisthorchis viverrini OX=6198 GN=T265_13055 PE=4 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 3.392e-24
Identity = 54/65 (83.08%), Postives = 61/65 (93.85%), Query Frame = 2

Query:   50 LPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            LP ++KILETPEDIQERREQVL+RYSAFKEATE RR +LE AK+YQYFKRDADELESW+LEK+QT
Sbjct:    4 LPIKVKILETPEDIQERREQVLSRYSAFKEATEYRRHRLEQAKRYQYFKRDADELESWMLEKLQT 68

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:103022593])

HSP 1 Score: 85.1149 bits (209), Expect = 5.299e-18
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSAMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 52.373 bits (124), Expect = 3.978e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  540 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKT 595

HSP 3 Score: 48.1358 bits (113), Expect = 7.826e-6
Identity = 26/55 (47.27%), Postives = 36/55 (65.45%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1473 PE-IFNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1526

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:103022593])

HSP 1 Score: 85.1149 bits (209), Expect = 5.464e-18
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSAMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 52.373 bits (124), Expect = 4.058e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  563 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKT 618

HSP 3 Score: 48.1358 bits (113), Expect = 7.772e-6
Identity = 26/55 (47.27%), Postives = 36/55 (65.45%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1546 PE-IFNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1599

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:103022593])

HSP 1 Score: 85.1149 bits (209), Expect = 5.567e-18
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSAMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 52.373 bits (124), Expect = 3.987e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  563 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKT 618

HSP 3 Score: 48.1358 bits (113), Expect = 7.981e-6
Identity = 26/55 (47.27%), Postives = 36/55 (65.45%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1546 PE-IFNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1599

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:103022593])

HSP 1 Score: 85.1149 bits (209), Expect = 5.614e-18
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSAMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 52.373 bits (124), Expect = 4.055e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  540 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKT 595

HSP 3 Score: 48.1358 bits (113), Expect = 8.046e-6
Identity = 26/55 (47.27%), Postives = 36/55 (65.45%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1492 PE-IFNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1545

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Match: sptan1 (spectrin alpha, non-erythrocytic 1 [Source:NCBI gene;Acc:103022593])

HSP 1 Score: 85.1149 bits (209), Expect = 5.722e-18
Identity = 38/60 (63.33%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET +DIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETADDIQERRQQVLDRYRRFKELSAMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

HSP 2 Score: 52.373 bits (124), Expect = 4.093e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  563 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFFRDSDELKSWINEKMKT 618

HSP 3 Score: 48.1358 bits (113), Expect = 8.266e-6
Identity = 26/55 (47.27%), Postives = 36/55 (65.45%), Query Frame = 2

Query:   80 PEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            PE I  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct: 1526 PE-IFNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 1579

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Medaka
Match: ENSORLT00000039102.1 (pep primary_assembly:ASM223467v1:12:24689488:24690705:-1 gene:ENSORLG00000023857.1 transcript:ENSORLT00000039102.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 1.130e-19
Identity = 39/60 (65.00%), Postives = 51/60 (85.00%), Query Frame = 2

Query:   62 IKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQ 241
            +K+LET EDIQERR+QVL+RY  FKE +  RR+KLED+ ++Q+F+RDADELE WI EK+Q
Sbjct:    6 VKVLETAEDIQERRQQVLDRYRRFKELSIMRRQKLEDSYRFQFFRRDADELEKWIQEKLQ 65

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Medaka
Match: ENSORLT00000045528.1 (pep primary_assembly:ASM223467v1:12:24685984:24689086:-1 gene:ENSORLG00000029984.1 transcript:ENSORLT00000045528.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 3.043e-7
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 2

Query:   77 TPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
              ED+  RR+ +L+R +A  E  + RR  LED+   Q F RD+DEL+SWI EK++T
Sbjct:  280 AKEDVATRRDALLSRRNALHERAQSRRAALEDSFHLQQFCRDSDELKSWINEKMKT 335

[Close]

BLAST of Spectrin alpha chain vs. Ensembl Medaka
Match: ENSORLT00000043413.1 (pep primary_assembly:ASM223467v1:12:24675012:24681272:-1 gene:ENSORLG00000023290.1 transcript:ENSORLT00000043413.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.2174 bits (121), Expect = 5.713e-7
Identity = 25/53 (47.17%), Postives = 35/53 (66.04%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            DI  RR +VL+R+   K    E+R KL +++  Q F RD DE+E+WI EK+QT
Sbjct:  226 DITNRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQT 278

[Close]

BLAST of Spectrin alpha chain vs. Planmine SMEST
Match: SMESG000017064.1 (SMESG000017064.1)

HSP 1 Score: 164.851 bits (416), Expect = 1.825e-45
Identity = 75/76 (98.68%), Postives = 76/76 (100.00%), Query Frame = 2

Query:  281 VKKTPIFMENLLLTGSKSDQWISIDIDTGEIIHKYQTGNIENCPHHESNNKVNRTMYIGICQYNLFVTEPNSRQLM 508
            VKKTPIFMENLLLTGSKSDQWISIDIDTGEIIHKYQTGNIENCPHHESNNKVNRTMYIGICQYNLFVTEPNSRQL+
Sbjct:  125 VKKTPIFMENLLLTGSKSDQWISIDIDTGEIIHKYQTGNIENCPHHESNNKVNRTMYIGICQYNLFVTEPNSRQLI 200

[Close]

BLAST of Spectrin alpha chain vs. Planmine SMEST
Match: SMESG000005289.1 (SMESG000005289.1)

HSP 1 Score: 142.51 bits (358), Expect = 1.286e-37
Identity = 70/70 (100.00%), Postives = 70/70 (100.00%), Query Frame = 2

Query:   35 MADITLPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            MADITLPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT
Sbjct:    1 MADITLPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 70

HSP 2 Score: 51.2174 bits (121), Expect = 6.342e-7
Identity = 23/53 (43.40%), Postives = 38/53 (71.70%), Query Frame = 2

Query:   86 DIQERREQVLNRYSAFKEATEERRKKLEDAKKYQYFKRDADELESWILEKIQT 244
            D+ ++R+ +L R S  +E  + R+  LED+  YQ F RDADE+++WI+EK++T
Sbjct:  547 DVNKKRDDLLIRKSNLEEKAKLRKSSLEDSHNYQLFDRDADEIKAWIVEKLKT 599

The following BLAST results are available for this feature:

BLAST of Spectrin alpha chain vs. Ensembl Human
BLAST of Spectrin alpha chain vs. Ensembl Celegans
BLAST of Spectrin alpha chain vs. Ensembl Fly
BLAST of Spectrin alpha chain vs. Ensembl Zebrafish
BLAST of Spectrin alpha chain vs. Ensembl Xenopus
BLAST of Spectrin alpha chain vs. Ensembl Mouse
BLAST of Spectrin alpha chain vs. UniProt/SwissProt
BLAST of Spectrin alpha chain vs. TrEMBL
BLAST of Spectrin alpha chain vs. Ensembl Cavefish
BLAST of Spectrin alpha chain vs. Ensembl Sea Lamprey
BLAST of Spectrin alpha chain vs. Ensembl Yeast
BLAST of Spectrin alpha chain vs. Ensembl Nematostella
BLAST of Spectrin alpha chain vs. Ensembl Medaka
BLAST of Spectrin alpha chain vs. Planmine SMEST

BLAST of Spectrin alpha chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SPTAN1	7.383e-20	61.90	spectrin alpha, non-erythrocytic 1 [Source:HGNC Sy...	[more]
SPTAN1	5.128e-18	61.90	spectrin alpha, non-erythrocytic 1 [Source:HGNC Sy...	[more]
SPTAN1	5.129e-18	61.90	spectrin alpha, non-erythrocytic 1 [Source:HGNC Sy...	[more]
SPTAN1	5.173e-18	61.90	spectrin alpha, non-erythrocytic 1 [Source:HGNC Sy...	[more]
SPTAN1	5.181e-18	61.90	spectrin alpha, non-erythrocytic 1 [Source:HGNC Sy...	[more]

BLAST of Spectrin alpha chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
spc-1	1.329e-17	58.73	SPeCtrin [Source:UniProtKB/TrEMBL;Acc:G4S034]	[more]
spc-1	1.329e-17	58.73	SPeCtrin [Source:UniProtKB/TrEMBL;Acc:G4S034]	[more]

BLAST of Spectrin alpha chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
alpha-Spec	2.734e-22	71.88	gene:FBgn0250789 transcript:FBtr0332879	[more]
alpha-Spec	2.761e-22	71.88	gene:FBgn0250789 transcript:FBtr0332878	[more]
alpha-Spec	2.783e-22	71.88	gene:FBgn0250789 transcript:FBtr0332880	[more]
alpha-Spec	2.835e-22	71.88	gene:FBgn0250789 transcript:FBtr0072789	[more]

BLAST of Spectrin alpha chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
sptan1	1.296e-17	63.33	spectrin alpha, non-erythrocytic 1 [Source:ZFIN;Ac...	[more]

BLAST of Spectrin alpha chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sptan1	1.605e-17	65.00	spectrin, alpha, non-erythrocytic 1 [Source:NCBI g...	[more]
sptan1	1.635e-17	65.00	spectrin, alpha, non-erythrocytic 1 [Source:NCBI g...	[more]
sptan1	1.649e-17	65.00	spectrin, alpha, non-erythrocytic 1 [Source:NCBI g...	[more]
sptan1	1.651e-17	65.00	spectrin, alpha, non-erythrocytic 1 [Source:NCBI g...	[more]
sptan1	1.682e-17	65.00	spectrin, alpha, non-erythrocytic 1 [Source:NCBI g...	[more]

BLAST of Spectrin alpha chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sptan1	1.928e-19	60.94	spectrin alpha, non-erythrocytic 1 [Source:MGI Sym...	[more]
Sptan1	3.119e-18	60.94	spectrin alpha, non-erythrocytic 1 [Source:MGI Sym...	[more]
Sptan1	3.151e-18	60.94	spectrin alpha, non-erythrocytic 1 [Source:MGI Sym...	[more]
Sptan1	3.177e-18	60.94	spectrin alpha, non-erythrocytic 1 [Source:MGI Sym...	[more]
Sptan1	3.208e-18	60.94	spectrin alpha, non-erythrocytic 1 [Source:MGI Sym...	[more]

BLAST of Spectrin alpha chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P13395\|SPTCA_DROME	2.842e-21	71.88	Spectrin alpha chain OS=Drosophila melanogaster OX...	[more]
sp\|P16086\|SPTN1_RAT	2.223e-17	60.94	Spectrin alpha chain, non-erythrocytic 1 OS=Rattus...	[more]
sp\|P16546\|SPTN1_MOUSE	2.223e-17	60.94	Spectrin alpha chain, non-erythrocytic 1 OS=Mus mu...	[more]
sp\|P07751\|SPTN1_CHICK	2.286e-17	61.90	Spectrin alpha chain, non-erythrocytic 1 OS=Gallus...	[more]
sp\|Q13813\|SPTN1_HUMAN	2.463e-17	61.90	Spectrin alpha chain, non-erythrocytic 1 OS=Homo s...	[more]

BLAST of Spectrin alpha chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4E0R0S1	4.596e-27	81.54	Spna2 protein OS=Fasciola hepatica OX=6192 GN=D915...	[more]
A0A5J4P2W7	7.960e-25	86.15	Spectrin alpha OS=Paragonimus westermani OX=34504 ...	[more]
A0A4S2M595	1.366e-24	84.62	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A419PZF6	1.379e-24	84.62	Spectrin alpha chain OS=Clonorchis sinensis OX=799...	[more]
A0A075AI56	3.392e-24	83.08	Spectrin repeat-containing domain protein OS=Opist...	[more]

BLAST of Spectrin alpha chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sptan1	5.299e-18	63.33	spectrin alpha, non-erythrocytic 1 [Source:NCBI ge...	[more]
sptan1	5.464e-18	63.33	spectrin alpha, non-erythrocytic 1 [Source:NCBI ge...	[more]
sptan1	5.567e-18	63.33	spectrin alpha, non-erythrocytic 1 [Source:NCBI ge...	[more]
sptan1	5.614e-18	63.33	spectrin alpha, non-erythrocytic 1 [Source:NCBI ge...	[more]
sptan1	5.722e-18	63.33	spectrin alpha, non-erythrocytic 1 [Source:NCBI ge...	[more]

BLAST of Spectrin alpha chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Spectrin alpha chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Spectrin alpha chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Spectrin alpha chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSORLT00000039102.1	1.130e-19	65.00	pep primary_assembly:ASM223467v1:12:24689488:24690...	[more]
ENSORLT00000045528.1	3.043e-7	46.43	pep primary_assembly:ASM223467v1:12:24685984:24689...	[more]
ENSORLT00000043413.1	5.713e-7	47.17	pep primary_assembly:ASM223467v1:12:24675012:24681...	[more]

BLAST of Spectrin alpha chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000017064.1	1.825e-45	98.68	SMESG000017064.1	[more]
SMESG000005289.1	1.286e-37	100.00	SMESG000005289.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001586 ID=SMED30001586|Name=Spectrin alpha chain|organism=Schmidtea mediterranea sexual|type=transcript|length=899bp
ATTTTCGCTTTCTGTTAGTTATTAAATATTTAAGATGGCTGATATAACTT
TACCGAAGGAAATAAAAATACTTGAAACTCCTGAGGATATTCAAGAAAGA
CGTGAGCAAGTATTAAATCGTTATTCGGCTTTCAAAGAAGCTACTGAGGA
GAGACGGAAAAAACTTGAAGATGCTAAAAAATATCAATACTTCAAGAGAG
ATGCTGATGAATTGGAAAGTTGGATATTGGAAAAAATTCAAACATATTCA
GATGAGCTTGAATATAGTCTTTATGAATATGTTAAGAAAACTCCAATTTT
CATGGAAAATTTATTATTGACTGGAAGTAAAAGTGATCAATGGATATCAA
TTGATATTGATACGGGAGAAATAATACATAAGTATCAAACTGGAAATATT
GAAAACTGTCCACATCATGAGTCAAATAACAAAGTAAATAGAACAATGTA
TATTGGAATTTGTCAATATAATTTATTTGTCACTGAGCCTAATAGTCGAC
AATTAATGTAAGTTATTTGATTTTTTTAGAATTTCGCGTATTTTTAAAAT
GATTTAAATTTAATTTCAAATTAATTATATTCTCTAAAAATTGTATTTAA
TATGCATTTCAATTATTTGACAAATAAAGGGGAAACTCTGGGAGATACAT
TACCCTACAAATAACTTGTTTAATAGATATTTGAATAATGAAAAAAATGT
TTATATCATTATTGAACGTAAAATATTTTGGCATAGAATAATCTGATATA
AACTGATAAAACACTAACGCAATTTTTTAAGCATCGAAATCAATCGGTTT
TCAAAAATATACTTACTATTATGGAGATGTTATTGACGAGAGGGATATCC
ATATATTGTATGTGCATTGCTGAGGAGGGAGGGGGATCTGCTACCCAAT

protein sequence of SMED30001586-orf-1

>SMED30001586-orf-1 ID=SMED30001586-orf-1|Name=SMED30001586-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=159bp
MADITLPKEIKILETPEDIQERREQVLNRYSAFKEATEERRKKLEDAKKY
QYFKRDADELESWILEKIQTYSDELEYSLYEYVKKTPIFMENLLLTGSKS
DQWISIDIDTGEIIHKYQTGNIENCPHHESNNKVNRTMYIGICQYNLFVT
EPNSRQLM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0000099	neuron
PLANA:0000463	cholinergic neuron
PLANA:0000464	GABAergic neuron
PLANA:0003116	parenchymal cell
PLANA:0007528	glial cell

Vocabulary: **INTERPRO**
Term	Definition
IPR011047	Quinoprotein_ADH-like_supfam

Vocabulary: **molecular function**
Term	Definition
GO:0005509	calcium ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 27..47
None	No IPR available	GENE3D	G3DSA:1.20.58.60		coord: 5..74 e-value: 1.9E-24 score: 88.2
None	No IPR available	PANTHER	PTHR11915	SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN	coord: 10..74
None	No IPR available	PANTHER	PTHR11915:SF427	SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1	coord: 10..74
None	No IPR available	SUPERFAMILY	SSF46966	Spectrin repeat	coord: 16..72

Main menu

Spectrin alpha chain

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Owlery

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