EF-hand calcium-binding domain-containing protein 6
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001575 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Human
Match: EFCAB6 (EF-hand calcium binding domain 6 [Source:HGNC Symbol;Acc:HGNC:24204]) HSP 1 Score: 118.627 bits (296), Expect = 2.309e-26 Identity = 155/702 (22.08%), Postives = 283/702 (40.31%), Query Frame = 1
Query: 838 IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKL----------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVA--EIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMY---------------------------NKSTASFPNAKLNPPVKGDSD-LMQRSRKLNAAT------DILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFK-TPNNKIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ +++ A Y+ K ++R L+ F ++ + + D+KN+LY I L P E EKLW ++D +G I +FL+++G I+Y A P + D F + + ++L + KL + + + F K D ++T ++SI +VL E L E L L+ ++ I Y +FL ++ G K + ++S I+ + LNP V K+ + + L + F DK G ++ +F +VL++ + T++Q+ + L R PY+++ ++ NFS E + + + P T S K A +I + +A S + I + F D ++ E F+ + V+ L+ +W +N K L + +F F +S S P +L P K S S + T D + LR +I + LLKE D G I+ DF ++++ ++ ++ E + + K+ N K AY + ++ K ++ + + G ++ SF+ ++Q I M R K D TG +S+A+ R +L ++LSE+E F+++ YDK L+ I+Y L+
Sbjct: 827 VADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLG-INYSPAVHRP---CAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPK-----EKEESMPINFATLNPQEAVR-KIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKD-FCYKLTDNQYHYFLRKL---RIHLTPYINW--KYFLQNFSCFLEETADEWAEKMPKGPPPT--------SPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISRE-EFRAICNRRVQI-LTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMATGDSAVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEA-----GAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLR 1497
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Human
Match: EFCAB6 (EF-hand calcium binding domain 6 [Source:HGNC Symbol;Acc:HGNC:24204]) HSP 1 Score: 118.627 bits (296), Expect = 2.787e-26 Identity = 155/702 (22.08%), Postives = 283/702 (40.31%), Query Frame = 1
Query: 838 IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKL----------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVA--EIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMY---------------------------NKSTASFPNAKLNPPVKGDSD-LMQRSRKLNAAT------DILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFK-TPNNKIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ +++ A Y+ K ++R L+ F ++ + + D+KN+LY I L P E EKLW ++D +G I +FL+++G I+Y A P + D F + + ++L + KL + + + F K D ++T ++SI +VL E L E L L+ ++ I Y +FL ++ G K + ++S I+ + LNP V K+ + + L + F DK G ++ +F +VL++ + T++Q+ + L R PY+++ ++ NFS E + + + P T S K A +I + +A S + I + F D ++ E F+ + V+ L+ +W +N K L + +F F +S S P +L P K S S + T D + LR +I + LLKE D G I+ DF ++++ ++ ++ E + + K+ N K AY + ++ K ++ + + G ++ SF+ ++Q I M R K D TG +S+A+ R +L ++LSE+E F+++ YDK L+ I+Y L+
Sbjct: 675 VADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLG-INYSPAVHRP---CAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPK-----EKEESMPINFATLNPQEAVR-KIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKD-FCYKLTDNQYHYFLRKL---RIHLTPYINW--KYFLQNFSCFLEETADEWAEKMPKGPPPT--------SPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISRE-EFRAICNRRVQI-LTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMATGDSAVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEA-----GAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLR 1345
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Zebrafish
Match: si:dkey-256e7.5 (si:dkey-256e7.5 [Source:ZFIN;Acc:ZDB-GENE-090313-282]) HSP 1 Score: 162.155 bits (409), Expect = 3.078e-43 Identity = 99/298 (33.22%), Postives = 182/298 (61.07%), Query Frame = 1
Query: 1876 TIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNK-IAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQ-FNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQD 2763
+++K +++ D+ + F ELDE N + LT E M+QL+K L E++RG++R +W + + +DF++F RHF + + FPNAK NPP +GD+D M+ S +L+ +DIL+D LRAK+++ ++L EF+ +D G +S ++F+EI+ L +HL+ +E ++ KF ++ ++YLE L+PF S QI ++ S+ L + + +Q ++ + + KLQ + A+ + ++DS ++G +S AEL A+L L GV S++E+ ++ ++ + +G ++Y+ LL D
Sbjct: 43 SLVKSLVANRYKDVLQVFEELDEKNTRRLTQEDMYQLLKRLVPHQEVTRGEVRRLWSSLFTQQDGTVDFQQFLRHFGPSPRSCCFPNAKRNPPKRGDNDFMRLSNRLSYVSDILVDALRAKVEMSVSELWTEFSEMDFSGTGFVSSDEFKEILMSLCVHLSQYECDVLARKFDINHDGCVSYLEFLRPFLSQS--QIWKHGSNMAAALQTPRENQEIATPETLNRNIRKKLQRKAK-ALSKACTRLDSSSSGLLSAAELGAVLQLLGVCQSQEELKSVFSTLHTHPSGCLDYRPLLLD 337
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Zebrafish
Match: si:dkey-256e7.5 (si:dkey-256e7.5 [Source:ZFIN;Acc:ZDB-GENE-090313-282]) HSP 1 Score: 92.8189 bits (229), Expect = 1.764e-21 Identity = 54/133 (40.60%), Postives = 80/133 (60.15%), Query Frame = 1
Query: 1183 IEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSS--NIDSELNPVSLVEFKLVNLFQKDFLEILENFR 1575
IE LK + R+G ++ +F K D TG + +DF+QVL + DL L+ LG FLSRC + K + Y FL FQDRS GITHK++ + ++ S N+ S + +S +E KL+ LFQ +FL +L+ F+
Sbjct: 21 IETWLKDRFRDGAQRMKAEFDKLDPESTGKVRGADFLQVLGKFDLHLKREQLGLFLSRCGLKIKKGCVQYLNFLRTFQDRSSDGITHKIIYNPKHRFHSVENV-SCASSLSAIEAKLIRLFQSEFLSLLKTFQ 152
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Xenopus
Match: immp2l (inner mitochondrial membrane peptidase subunit 2 [Source:Xenbase;Acc:XB-GENE-1010851]) HSP 1 Score: 134.42 bits (337), Expect = 2.851e-31 Identity = 186/846 (21.99%), Postives = 340/846 (40.19%), Query Frame = 1
Query: 520 LSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEK-------------QMLSFNEIYTIFVNKSKEKSETSFFDPV--NRHKAKAIVPAK-MTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSIT-KADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGII-----SYPIASLTPNVRAS-----NDSFKLN-------------LNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILE-----------NFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLM-KTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRH--------------------FMYNKSTASFPN-----------------AKLNPPVKGDSDLMQRSRKLNAATDI-----LMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSF-HFFHKLQAVI---QSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+S E+ L++KL++ Y ++ F D +R G V ++ M+ IK ++ L++ E +F +K ++ + P + H K + + + A Y+ K + R + F + ++S+ I K DL+N L++ + + P E EKLW ++D +G + +FL+++GI S P +T + RA N+ K+ L+ IE+ +K K R+ + F K D N+ G +S+ D +L + L++ L R I T + Y +FL +++ D+ ++S PVS E QK L++ E F FD+ G+I+ + ++L++ + ++ QF ++ LPL QT+ + FL F T + E SS E V G T+ +I +++ ++F + + F LD N ++ E +L K + L+ ++W T LN L + EF F+Y ++A N A LN P K D+ QR + A++ + + LR + ++ ++L+ DPE G I+ DF ++K+ + + E+ +T K+ + NN K +Y + + + LE S + K+ ++ G D F + ++Q + M R D TGFIS+ E + +L G++LSEDE F+++ +DK+L ++Y L+
Sbjct: 741 MSAEDCLAQLRDKLQQGYGDLYSAFYKIDSNRDGLVTMHDFRHLLDSF---------------MFIIKPQEFQRLLGLLGLNLSSTLNYKEFLHLF-----QKPQSPVYPPWLQSSHSPKQSMGGEDLACEQAHYYLVTKAQGRWHDMAKTFCE-IDSEGNGIVQKKDLRNVLFRFYLPIHPKEFEKLWGRYDPEGKGFLTHNEFLEKLGISFASGDSGPSKQITEDNRACLEGHYNNQLKIQEEMDAFHKHQTKALDMKDIEQQIKDKFRDYYHDFSAAFAKIDRNKDGQISVHDLRAMLQSLNFHLDDEQFANLLYRLRIKVTDNKLSYPDFL-------------RMI---DDGRASKYGQRQRPVSAAETPPKLSLQKVLLKLKEAVVSSHDALYKAFSSFDRDGTGTIKASELHQILDS-FCFKLSDRQFGYLLSKLPLGEEQTIDWKAFLHHFSTSH---------PEPSSSWVER--VQHATRPRSTQGLTMKDILNHIREVVTARFYTVAQDFISLDYANINAVSKEDFRELFNKDFML---LTDEQFENLWNTLPLNPYGNLKYHEFLSQFGGGDALVSPYEKTAGDQSEFIYKPASALAGNHTPPESQAGIRRPKTAPAILNKP-KTDT---QRPKTAGASSRLVNCEQIEARLRGSLQKVWQEVLRACRDYDPERTGEITTNDFSGVLKQFNAETNEEELERLTVKYDSRNNGKFSYADFFRNIML--GPKPLEKSPLHRMKVQKTRVPISTGPDGPCFLNAMMRIQPKVLDCWRPMRRAFLSFDEARTGFISVQEFKQVLRKSGLNLSEDEFFHILGFFDKDLKAKVSYNDFLR 1528 HSP 2 Score: 87.4261 bits (215), Expect = 9.800e-17 Identity = 108/450 (24.00%), Postives = 204/450 (45.33%), Query Frame = 1
Query: 1486 DSELNPVSL--VEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAE-IKTIMKQA--FDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHF-----MYNKSTASFPNAKLN-PPVKGDSDLMQRSR-----KLNAATDILMDN----LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDS--NSFHFFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLL 2757
D L P+ + + ++ VN ++D + F D QN ++ +F +VL+N + + TESQF +++ +P+N N T+PYLDFL +F + S+ + + S ++A+ V N EI+ TV++ +K +++ FD +N+ NG++ EL ++++ K + + +W + + +K LD++E R+ ++NK TA + LN V+ + + R K +A D +D+ LR KI Y +L+K F D ++G +S E Q +I L + + + ++ ++I + + L+ F +S + + +++ G+ +S H KLQ Q A + + +D G G IS ELR ++ +++ + LM D G I+Y L
Sbjct: 51 DPTLTPLEIEGIIYRRVNENEED---VTNAFLTLDTEQNFTVTRGEFYRVLQNFI-LPLTESQFNELLEKIPVNNNGTIPYLDFLAKFLRTSSSATCARSVKRSWSC-SQANQVLSLNELEIRLKNTVSKNLKNVVRSCRLFD---------YNQ----NGQIQKQELR-RILENCCFK--MKTAEFEKLWNRYCIGKKNTLDYRELLRNLGVNVELHNKPTAENVASALNREAVQREQQKEKNCRPPPPLKELSAEDYTIDDIEAALRKKISASYPNLVKAFRAFDGSHSGYVSAEALQSVINNFIFPLPNGTFQKLMNRLAIKCTDRIGWEQFLRRFQGPESMA----NGQTIPMKPNHRVNPVRGESPVVSSEHILQKLQRHFQDAYPSLKQAFLVLDEGRKGRISRKELRRIVDCMMFRVTDAQFKELMIILDPQHTGFISYLQFL 475 HSP 3 Score: 68.9366 bits (167), Expect = 4.515e-11 Identity = 124/635 (19.53%), Postives = 246/635 (38.74%), Query Frame = 1
Query: 679 TTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNA---------------------------SFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEF---KLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQF-DTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDS--------DLMQRSRKLNAATDILMDNLRAK--IDLLYNDLLKE-------FTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPF 2439
+ +C S+ W Q+LS NE+ E + V+++ + ++ FDY +Q I K +L+ L + E EKLW ++ K+ ++D + L+ +G+ L A N + LN A IE L+ K+ + L + F+ D + +G++S V++ L + ++R I T + I +++FL RFQ E+ + + + N + + + E +PV E KL FQ + + + F D+ + G I K+ +++++ M T++QFK ++ L + YL FL F D + S + +H + L E PVT +E + G I+ + + + D K D ++ + +++++ P LS + + + + + +F R+ S A N V G DL R +++ + L+ + + I L + ++ + F ++ G IS +DF+++++E IHL + + + +T+K +++YL+ + F
Sbjct: 140 SATCARSVKRSWSCSQANQVLSLNEL------------EIRLKNTVSKNLKNVVRSCRL-----FDY---------------------NQNGQIQKQELRRILENCCFKMKTAEFEKLWNRYCIGKKNTLDYRELLRNLGVN----VELHNKPTAENVASALNREAVQREQQKEKNCRPPPPLKELSAEDYTIDDIEAALRKKISASYPNLVKAFRAFDGSHSGYVSAEALQSVINNFIFPLPNGTFQKLMNRLAIKCT-DRIGWEQFLRRFQG-PESMANGQTIPMKPNHRVNPVRGE-SPVVSSEHILQKLQRHFQDAYPSLKQAFLVLDEGRKGRISRKELRRIVDCMM-FRVTDAQFKELMIILDPQHTGFISYLQFLDLFEDKESVSGHKW--LHNMRTPLKET-PVT---LEWEKMG-------NILCEKIEHNWADFSKAMKSCDSAGCGMVDKDQFKRILQSF--CPPLSDRHYNMLCEQYNDGANGYISYMDFLRNVGVCTSAAGDLNGVSTEIVHGSQLREELRQDDLSARMKEIESQATQLVKKMPVEEVIGKLKDCVIGQEFSPRESFLAFAKQHKGRISKKDFRKVLREHEIHLDEDQFKRLTEKLGFTKEELSYLDFVSLF 713 HSP 4 Score: 53.5286 bits (127), Expect = 2.215e-6 Identity = 125/669 (18.68%), Postives = 260/669 (38.86%), Query Frame = 1
Query: 517 KLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFI-----EKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEG-IPYKEFL----IRFQDRSEAGITHKLLTDRDNKKSSNIDSELN----------------PVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLN-RNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFK-TPNNKIAYLELLKPF 2439
K+ +EE+ L++ + + R+ F+ KG + K+ +++++ + L E G E+ LS+ + ++F + + + D + H M+A D +++K + L F ++ +T D ++ L M + P E ++L +++ +FL + P + + P S+ S K ++ + L TK + + + + F + D+ G + D VL L + + R P +G + + EFL I F ++G + ++ D + +++L + +E ++ + F+ + + F K D+ ++G I + D + +L++ +N + QF ++ L + + + Y DFL+ D G S PV+ E ++ ++ +K+A S + K F+ D + + Q++ + K LS + L E++ +D+K F HF + S P + + RS + DIL +++R + + + ++F LD N A+S EDF+E+ + + LTD + + + P + Y E L F
Sbjct: 633 KMPVEEVIGKLKDCVIGQEFSPRESFLAFAKQHKGRISKKDFRKVLRE-HEIHLDEDQFKRLTEKLGFTKEE--LSYLDFVSLFEDPTGNGPGAAL-DTGSNHHVNDTKFHYMSAEDCLAQLRDKLQQGYGDLYSAFYKIDSNRDGLVTMHDFRHLLDSFMFIIKPQEFQRLLGLLGLNLSSTLNYKEFLH---LFQKPQSPVYPPWLQSSHSPKQSMGGEDLACEQAHYYLVTKAQGRWHDMAKTFCEIDSEGNGIVQKKDLRNVLFRFYLPIHPKEFEKLWGR--YDPEGKGFLTHNEFLEKLGISFAS-GDSGPSKQITEDNRACLEGHYNNQLKIQEEMDAFHKHQTKALDMKDIEQQIKDKFRDYYHDFSAAFAKIDRNKDGQISVHDLRAMLQS-LNFHLDDEQFANLLYRLRIKVTDNKLSYPDFLRMIDDGRASKYG-----------QRQRPVS---AAETPPKLSLQKVLLKLKEAVVSSHDALYKAFSSFDRDGTGTIKASELHQILDSFCFK--LSDRQFGYLLSKLPLGEEQTIDWKAFLHHF-----STSHPEPSSSWVERVQHATRPRSTQGLTMKDIL-NHIREVVTARFYTVAQDFISLDYANINAVSKEDFRELFNKDFMLLTDEQFENLWNTLPLNPYGNLKYHEFLSQF 1268
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Xenopus
Match: immp2l (inner mitochondrial membrane peptidase subunit 2 [Source:Xenbase;Acc:XB-GENE-1010851]) HSP 1 Score: 134.035 bits (336), Expect = 3.877e-31 Identity = 186/846 (21.99%), Postives = 340/846 (40.19%), Query Frame = 1
Query: 520 LSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEK-------------QMLSFNEIYTIFVNKSKEKSETSFFDPV--NRHKAKAIVPAK-MTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSIT-KADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGII-----SYPIASLTPNVRAS-----NDSFKLN-------------LNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILE-----------NFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLM-KTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRH--------------------FMYNKSTASFPN-----------------AKLNPPVKGDSDLMQRSRKLNAATDI-----LMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSF-HFFHKLQAVI---QSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+S E+ L++KL++ Y ++ F D +R G V ++ M+ IK ++ L++ E +F +K ++ + P + H K + + + A Y+ K + R + F + ++S+ I K DL+N L++ + + P E EKLW ++D +G + +FL+++GI S P +T + RA N+ K+ L+ IE+ +K K R+ + F K D N+ G +S+ D +L + L++ L R I T + Y +FL +++ D+ ++S PVS E QK L++ E F FD+ G+I+ + ++L++ + ++ QF ++ LPL QT+ + FL F T + E SS E V G T+ +I +++ ++F + + F LD N ++ E +L K + L+ ++W T LN L + EF F+Y ++A N A LN P K D+ QR + A++ + + LR + ++ ++L+ DPE G I+ DF ++K+ + + E+ +T K+ + NN K +Y + + + LE S + K+ ++ G D F + ++Q + M R D TGFIS+ E + +L G++LSEDE F+++ +DK+L ++Y L+
Sbjct: 717 MSAEDCLAQLRDKLQQGYGDLYSAFYKIDSNRDGLVTMHDFRHLLDSF---------------MFIIKPQEFQRLLGLLGLNLSSTLNYKEFLHLF-----QKPQSPVYPPWLQSSHSPKQSMGGEDLACEQAHYYLVTKAQGRWHDMAKTFCE-IDSEGNGIVQKKDLRNVLFRFYLPIHPKEFEKLWGRYDPEGKGFLTHNEFLEKLGISFASGDSGPSKQITEDNRACLEGHYNNQLKIQEEMDAFHKHQTKALDMKDIEQQIKDKFRDYYHDFSAAFAKIDRNKDGQISVHDLRAMLQSLNFHLDDEQFANLLYRLRIKVTDNKLSYPDFL-------------RMI---DDGRASKYGQRQRPVSAAETPPKLSLQKVLLKLKEAVVSSHDALYKAFSSFDRDGTGTIKASELHQILDS-FCFKLSDRQFGYLLSKLPLGEEQTIDWKAFLHHFSTSH---------PEPSSSWVER--VQHATRPRSTQGLTMKDILNHIREVVTARFYTVAQDFISLDYANINAVSKEDFRELFNKDFML---LTDEQFENLWNTLPLNPYGNLKYHEFLSQFGGGDALVSPYEKTAGDQSEFIYKPASALAGNHTPPESQAGIRRPKTAPAILNKP-KTDT---QRPKTAGASSRLVNCEQIEARLRGSLQKVWQEVLRACRDYDPERTGEITTNDFSGVLKQFNAETNEEELERLTVKYDSRNNGKFSYADFFRNIML--GPKPLEKSPLHRMKVQKTRVPISTGPDGPCFLNAMMRIQPKVLDCWRPMRRAFLSFDEARTGFISVQEFKQVLRKSGLNLSEDEFFHILGFFDKDLKAKVSYNDFLR 1504 HSP 2 Score: 87.0409 bits (214), Expect = 1.290e-16 Identity = 108/450 (24.00%), Postives = 204/450 (45.33%), Query Frame = 1
Query: 1486 DSELNPVSL--VEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAE-IKTIMKQA--FDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHF-----MYNKSTASFPNAKLN-PPVKGDSDLMQRSR-----KLNAATDILMDN----LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDS--NSFHFFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLL 2757
D L P+ + + ++ VN ++D + F D QN ++ +F +VL+N + + TESQF +++ +P+N N T+PYLDFL +F + S+ + + S ++A+ V N EI+ TV++ +K +++ FD +N+ NG++ EL ++++ K + + +W + + +K LD++E R+ ++NK TA + LN V+ + + R K +A D +D+ LR KI Y +L+K F D ++G +S E Q +I L + + + ++ ++I + + L+ F +S + + +++ G+ +S H KLQ Q A + + +D G G IS ELR ++ +++ + LM D G I+Y L
Sbjct: 51 DPTLTPLEIEGIIYRRVNENEED---VTNAFLTLDTEQNFTVTRGEFYRVLQNFI-LPLTESQFNELLEKIPVNNNGTIPYLDFLAKFLRTSSSATCARSVKRSWSC-SQANQVLSLNELEIRLKNTVSKNLKNVVRSCRLFD---------YNQ----NGQIQKQELR-RILENCCFK--MKTAEFEKLWNRYCIGKKNTLDYRELLRNLGVNVELHNKPTAENVASALNREAVQREQQKEKNCRPPPPLKELSAEDYTIDDIEAALRKKISASYPNLVKAFRAFDGSHSGYVSAEALQSVINNFIFPLPNGTFQKLMNRLAIKCTDRIGWEQFLRRFQGPESMA----NGQTIPMKPNHRVNPVRGESPVVSSEHILQKLQRHFQDAYPSLKQAFLVLDEGRKGRISRKELRRIVDCMMFRVTDAQFKELMIILDPQHTGFISYLQFL 475 HSP 3 Score: 53.1434 bits (126), Expect = 2.730e-6 Identity = 125/669 (18.68%), Postives = 260/669 (38.86%), Query Frame = 1
Query: 517 KLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFI-----EKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEG-IPYKEFL----IRFQDRSEAGITHKLLTDRDNKKSSNIDSELN----------------PVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLN-RNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFK-TPNNKIAYLELLKPF 2439
K+ +EE+ L++ + + R+ F+ KG + K+ +++++ + L E G E+ LS+ + ++F + + + D + H M+A D +++K + L F ++ +T D ++ L M + P E ++L +++ +FL + P + + P S+ S K ++ + L TK + + + + F + D+ G + D VL L + + R P +G + + EFL I F ++G + ++ D + +++L + +E ++ + F+ + + F K D+ ++G I + D + +L++ +N + QF ++ L + + + Y DFL+ D G S PV+ E ++ ++ +K+A S + K F+ D + + Q++ + K LS + L E++ +D+K F HF + S P + + RS + DIL +++R + + + ++F LD N A+S EDF+E+ + + LTD + + + P + Y E L F
Sbjct: 609 KMPVEEVIGKLKDCVIGQEFSPRESFLAFAKQHKGRISKKDFRKVLRE-HEIHLDEDQFKRLTEKLGFTKEE--LSYLDFVSLFEDPTGNGPGAAL-DTGSNHHVNDTKFHYMSAEDCLAQLRDKLQQGYGDLYSAFYKIDSNRDGLVTMHDFRHLLDSFMFIIKPQEFQRLLGLLGLNLSSTLNYKEFLH---LFQKPQSPVYPPWLQSSHSPKQSMGGEDLACEQAHYYLVTKAQGRWHDMAKTFCEIDSEGNGIVQKKDLRNVLFRFYLPIHPKEFEKLWGR--YDPEGKGFLTHNEFLEKLGISFAS-GDSGPSKQITEDNRACLEGHYNNQLKIQEEMDAFHKHQTKALDMKDIEQQIKDKFRDYYHDFSAAFAKIDRNKDGQISVHDLRAMLQS-LNFHLDDEQFANLLYRLRIKVTDNKLSYPDFLRMIDDGRASKYG-----------QRQRPVS---AAETPPKLSLQKVLLKLKEAVVSSHDALYKAFSSFDRDGTGTIKASELHQILDSFCFK--LSDRQFGYLLSKLPLGEEQTIDWKAFLHHF-----STSHPEPSSSWVERVQHATRPRSTQGLTMKDIL-NHIREVVTARFYTVAQDFISLDYANINAVSKEDFRELFNKDFMLLTDEQFENLWNTLPLNPYGNLKYHEFLSQF 1244
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Xenopus
Match: immp2l (inner mitochondrial membrane peptidase subunit 2 [Source:Xenbase;Acc:XB-GENE-1010851]) HSP 1 Score: 103.99 bits (258), Expect = 8.036e-22 Identity = 132/591 (22.34%), Postives = 238/591 (40.27%), Query Frame = 1
Query: 1156 FKLNLNASFIEKLL-KTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILEN-----------FRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLM-KTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHF--------------------MYNKSTASFPN-------AKLNPPVKGDSDL------MQRSRKLNAATDI-----LMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSF-HFFHKLQAVI---QSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
F L ++ EKL + K R+ + F K D N+ G +S+ D +L + L++ L R I T + Y +FL +++ D+ ++S PVS E QK L++ E F FD+ G+I+ + ++L++ + ++ QF ++ LPL QT+ + FL F T + E SS E V G T+ +I +++ ++F + + F LD N ++ E +L K + L+ ++W T LN L + EF F +Y ++A N A + P + L QR + A++ + + LR + ++ ++L+ DPE G I+ DF ++K+ + + E+ +T K+ + NN K +Y + + + LE S + K+ ++ G D F + ++Q + M R D TGFIS+ E + +L G++LSEDE F+++ +DK+L ++Y L+
Sbjct: 895 FYLPIHPKEFEKLWGRDKFRDYYHDFSAAFAKIDRNKDGQISVHDLRAMLQSLNFHLDDEQFANLLYRLRIKVTDNKLSYPDFL-------------RMI---DDGRASKYGQRQRPVSAAETPPKLSLQKVLLKLKEAVVSSHDALYKAFSSFDRDGTGTIKASELHQILDS-FCFKLSDRQFGYLLSKLPLGEEQTIDWKAFLHHFSTSH---------PEPSSSWVER--VQHATRPRSTQGLTMKDILNHIREVVTARFYTVAQDFISLDYANINAVSKEDFRELFNKDFML---LTDEQFENLWNTLPLNPYGNLKYHEFLSQFGGGDALVSPYEKTAGDQSEFIYKPASALAGNHTPPESQAGIRRPKTAPAILNKPKTDTQRPKTAGASSRLVNCEQIEARLRGSLQKVWQEVLRACRDYDPERTGEITTNDFSGVLKQFNAETNEEELERLTVKYDSRNNGKFSYADFFRNIML--GPKPLEKSPLHRMKVQKTRVPISTGPDGPCFLNAMMRIQPKVLDCWRPMRRAFLSFDEARTGFISVQEFKQVLRKSGLNLSEDEFFHILGFFDKDLKAKVSYNDFLR 1452 HSP 2 Score: 87.4261 bits (215), Expect = 9.005e-17 Identity = 108/450 (24.00%), Postives = 204/450 (45.33%), Query Frame = 1
Query: 1486 DSELNPVSL--VEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAE-IKTIMKQA--FDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHF-----MYNKSTASFPNAKLN-PPVKGDSDLMQRSR-----KLNAATDILMDN----LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDS--NSFHFFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLL 2757
D L P+ + + ++ VN ++D + F D QN ++ +F +VL+N + + TESQF +++ +P+N N T+PYLDFL +F + S+ + + S ++A+ V N EI+ TV++ +K +++ FD +N+ NG++ EL ++++ K + + +W + + +K LD++E R+ ++NK TA + LN V+ + + R K +A D +D+ LR KI Y +L+K F D ++G +S E Q +I L + + + ++ ++I + + L+ F +S + + +++ G+ +S H KLQ Q A + + +D G G IS ELR ++ +++ + LM D G I+Y L
Sbjct: 51 DPTLTPLEIEGIIYRRVNENEED---VTNAFLTLDTEQNFTVTRGEFYRVLQNFI-LPLTESQFNELLEKIPVNNNGTIPYLDFLAKFLRTSSSATCARSVKRSWSC-SQANQVLSLNELEIRLKNTVSKNLKNVVRSCRLFD---------YNQ----NGQIQKQELR-RILENCCFK--MKTAEFEKLWNRYCIGKKNTLDYRELLRNLGVNVELHNKPTAENVASALNREAVQREQQKEKNCRPPPPLKELSAEDYTIDDIEAALRKKISASYPNLVKAFRAFDGSHSGYVSAEALQSVINNFIFPLPNGTFQKLMNRLAIKCTDRIGWEQFLRRFQGPESMA----NGQTIPMKPNHRVNPVRGESPVVSSEHILQKLQRHFQDAYPSLKQAFLVLDEGRKGRISRKELRRIVDCMMFRVTDAQFKELMIILDPQHTGFISYLQFL 475 HSP 3 Score: 68.5514 bits (166), Expect = 4.735e-11 Identity = 124/635 (19.53%), Postives = 246/635 (38.74%), Query Frame = 1
Query: 679 TTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNA---------------------------SFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEF---KLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQF-DTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDS--------DLMQRSRKLNAATDILMDNLRAK--IDLLYNDLLKE-------FTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPF 2439
+ +C S+ W Q+LS NE+ E + V+++ + ++ FDY +Q I K +L+ L + E EKLW ++ K+ ++D + L+ +G+ L A N + LN A IE L+ K+ + L + F+ D + +G++S V++ L + ++R I T + I +++FL RFQ E+ + + + N + + + E +PV E KL FQ + + + F D+ + G I K+ +++++ M T++QFK ++ L + YL FL F D + S + +H + L E PVT +E + G I+ + + + D K D ++ + +++++ P LS + + + + + +F R+ S A N V G DL R +++ + L+ + + I L + ++ + F ++ G IS +DF+++++E IHL + + + +T+K +++YL+ + F
Sbjct: 140 SATCARSVKRSWSCSQANQVLSLNEL------------EIRLKNTVSKNLKNVVRSCRL-----FDY---------------------NQNGQIQKQELRRILENCCFKMKTAEFEKLWNRYCIGKKNTLDYRELLRNLGVN----VELHNKPTAENVASALNREAVQREQQKEKNCRPPPPLKELSAEDYTIDDIEAALRKKISASYPNLVKAFRAFDGSHSGYVSAEALQSVINNFIFPLPNGTFQKLMNRLAIKCT-DRIGWEQFLRRFQG-PESMANGQTIPMKPNHRVNPVRGE-SPVVSSEHILQKLQRHFQDAYPSLKQAFLVLDEGRKGRISRKELRRIVDCMM-FRVTDAQFKELMIILDPQHTGFISYLQFLDLFEDKESVSGHKW--LHNMRTPLKET-PVT---LEWEKMG-------NILCEKIEHNWADFSKAMKSCDSAGCGMVDKDQFKRILQSF--CPPLSDRHYNMLCEQYNDGANGYISYMDFLRNVGVCTSAAGDLNGVSTEIVHGSQLREELRQDDLSARMKEIESQATQLVKKMPVEEVIGKLKDCVIGQEFSPRESFLAFAKQHKGRISKKDFRKVLREHEIHLDEDQFKRLTEKLGFTKEELSYLDFVSLF 713
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Xenopus
Match: ENSXETT00000007484.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:35434641:35435264:1 gene:ENSXETG00000002733.1 transcript:ENSXETT00000007484.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.1434 bits (126), Expect = 3.736e-8 Identity = 22/53 (41.51%), Postives = 39/53 (73.58%), Query Frame = 1
Query: 2602 KIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
K+D ++G++S+ E +++L L L EDEV+++M+ YD+N++G INYK L+
Sbjct: 7 KLDMDSSGYLSLPEFKSVLKLCNFVLDEDEVYHIMSKYDQNMDGRINYKSFLE 59
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Mouse
Match: Efcab6 (EF-hand calcium binding domain 6 [Source:MGI Symbol;Acc:MGI:1924877]) HSP 1 Score: 92.4337 bits (228), Expect = 1.884e-18 Identity = 164/800 (20.50%), Postives = 315/800 (39.38%), Query Frame = 1
Query: 520 LSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKA-IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASF---------IEKLLKTKLREGFTTLRQDFQKK--DTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNK---------------------STASFPNAK----LNPPVKGDSDLMQRSRKLNAATDILMDN-------LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+S EE I KL++++ +V F D DR G + R++Q + + + G++ LS + F N +++ S P + K + +++ A Y+ K ++R L+ F ++ + + D+KNSLY I L P E EKLW +D +G I +FL ++GI +P V N F I++L + RE ++ K ++ +++ +VL E L+E L L ++ I EFL + + K +++ I S++ P +++ + + + ++E F DK G ++ +F VL + + + T++Q+ + L L+ + + FL+ F T F + +D E + +A P + +E VA + ++A S + I + F D ++ + F+ + T ++ L+ +W +N K L +++F + S F +PP L RS + N LR +I + +LL+E D + G IS +F ++++ + ++ E + + K+ NN K AY + ++ K ++ + + G ++ SF+ ++Q I M R+ K D TG +S+A+ R +L ++LSE+E F+++ YDK+L+ I+Y L+
Sbjct: 748 ISAEECLRIFPKKLKESFRDVYSAFFRIDLDRDGIISMHDFHRLLQ-YLQLNMVDLEFERFLSLLGLR-----LSVTLNFREFQNLCEKRPWKSDEAPQRLIRCKQKVADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPREFEKLWQNYDTEGRGYITYQEFLHRLGI------RYSPKVHRPYKEDYFNFLGHFTKPKQVQEEIQELQQISEREKLMNHYEEISKAFNAMEKSKPVALCRVQKVLQECGCPLKEEELISLLKSLDVSVHNNHIDPVEFLRALEISWASKARPK---EKEESSPPPISFSKVTPDEVIK-TMQEVVESSQPALVEAFSALDKEDTGFVKAMEFGDVLRS-VCQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFST--FQDETADDWAEN---MPKAPP--PMSPKETAHRDIVARV----QKAVASHYHTIVQEFENFDTLKSNTVSRD-EFRSICTRHIQI-LTDEQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGDSGESTMAQRGSSAPEFSQGTRSNLYSPPRDSRVGLKSRSHPCTPVGTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEA-----GMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADFRKVLRQYSINLSEEEFFHVLEYYDKSLSSKISYNDFLR 1512
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. UniProt/SwissProt
Match: sp|Q4R8T1|EFCB6_MACFA (EF-hand calcium-binding domain-containing protein 6 (Fragment) OS=Macaca fascicularis OX=9541 GN=EFCAB6 PE=2 SV=2) HSP 1 Score: 120.939 bits (302), Expect = 7.592e-27 Identity = 148/662 (22.36%), Postives = 274/662 (41.39%), Query Frame = 1
Query: 958 ITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKL----------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVA--EIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYN---------------------------KSTASFPNAKLNPPVKGDSDLMQRSRKLNAA-------TDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ + D+KN+LY I L P E EKLW +D +G I +FL+++G ++Y A P + D F + + ++L + KL + + + + F K D ++T ++SI +VL E L E L L+ ++ I Y +FL ++ G K + ++S I+ + LNP +V K+ + + L + F DK G ++ +F +VL++ + + T++Q+ + L R PY+++ ++ NFS E + + + P T S K +A +I + +A S + I + F D ++ E F+ + +V+ L+ +W +N K L + +F F +S S PN +L P K S + D + LR +I + LLKE D G IS +F ++++ ++ ++ E + + K+ NN K AY + ++ K +++ + +G +++SF+ ++Q I M R K D TG +S+A+ R +L ++LSE+E F+++ YDK L+ +I+Y L+
Sbjct: 12 LRRRDIKNALYGFDIPLTPREFEKLWASYDTEGKGHITYQEFLQKLG-VNYSPAVHRP---CAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLVDCYQDISKAFTKIDKSKTNYISICKMQKVLEECGCSLTEGELTNLLNSWGVSRHDNSINYLDFLRAVENSKSTGAQPK-----EKEESMPINFATLNPQEVVR-KIQEVVESSQLALSTAFSALDKEDTGFVKSTEFGQVLKDFCH-KLTDNQYHYFLRKL---RIHLTPYINW--KYFLQNFSCFLEETAEEWAEKMPKGPPPT--------SPKAMASRDILARLHKAVTSHYHAITQEFENFDTMKTNTISRE-EFRAVCNRNVQI-LTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSERAATPTATGDSAAAQRGSSVPDVSEGIRSALSLPNQELRPGSKPQSHPCTAASTTAIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDISASEFLALVEKFNLDISKEECQQLIIKYDLKNNGKFAYCDFIQSCVLLLKAKESSLMQRMKIQNAHKMKD-----SGAETSSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSNISYNDFLR 642
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. UniProt/SwissProt
Match: sp|Q5THR3|EFCB6_HUMAN (EF-hand calcium-binding domain-containing protein 6 OS=Homo sapiens OX=9606 GN=EFCAB6 PE=1 SV=1) HSP 1 Score: 118.627 bits (296), Expect = 1.109e-25 Identity = 155/702 (22.08%), Postives = 283/702 (40.31%), Query Frame = 1
Query: 838 IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKL----------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVA--EIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMY---------------------------NKSTASFPNAKLNPPVKGDSD-LMQRSRKLNAAT------DILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFK-TPNNKIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ +++ A Y+ K ++R L+ F ++ + + D+KN+LY I L P E EKLW ++D +G I +FL+++G I+Y A P + D F + + ++L + KL + + + F K D ++T ++SI +VL E L E L L+ ++ I Y +FL ++ G K + ++S I+ + LNP V K+ + + L + F DK G ++ +F +VL++ + T++Q+ + L R PY+++ ++ NFS E + + + P T S K A +I + +A S + I + F D ++ E F+ + V+ L+ +W +N K L + +F F +S S P +L P K S S + T D + LR +I + LLKE D G I+ DF ++++ ++ ++ E + + K+ N K AY + ++ K ++ + + G ++ SF+ ++Q I M R K D TG +S+A+ R +L ++LSE+E F+++ YDK L+ I+Y L+
Sbjct: 827 VADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQKLG-INYSPAVHRP---CAEDYFNFMGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKAFTKTDQSKTNYISICKMQEVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKSTGAQPK-----EKEESMPINFATLNPQEAVR-KIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKD-FCYKLTDNQYHYFLRKL---RIHLTPYINW--KYFLQNFSCFLEETADEWAEKMPKGPPPT--------SPKATADRDILARLHKAVTSHYHAITQEFENFDTMKTNTISRE-EFRAICNRRVQI-LTDEQFDRLWNEMPVNAKGRLKYPDFLSRFSSETAATPMATGDSAVAQRGSSVPDVSEGTRSALSLPTQELRPGSKSQSHPCTPASTTVIPGTPPLQNCDPIESRLRKRIQGCWRQLLKECKEKDVARQGDINASDFLALVEKFNLDISKEECQQLIIKYDLKSNGKFAYCDFIQSCVLLLKAKESSLMHRMKIQNAHKMKEA-----GAETPSFYSALLRIQPKIVHCWRPMRRTFKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFLR 1497
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. UniProt/SwissProt
Match: sp|Q6P1E8|EFCB6_MOUSE (EF-hand calcium-binding domain-containing protein 6 OS=Mus musculus OX=10090 GN=Efcab6 PE=1 SV=2) HSP 1 Score: 92.4337 bits (228), Expect = 1.318e-17 Identity = 164/800 (20.50%), Postives = 315/800 (39.38%), Query Frame = 1
Query: 520 LSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKA-IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASF---------IEKLLKTKLREGFTTLRQDFQKK--DTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNK---------------------STASFPNAK----LNPPVKGDSDLMQRSRKLNAATDILMDN-------LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKP---FCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+S EE I KL++++ +V F D DR G + R++Q + + + G++ LS + F N +++ S P + K + +++ A Y+ K ++R L+ F ++ + + D+KNSLY I L P E EKLW +D +G I +FL ++GI +P V N F I++L + RE ++ K ++ +++ +VL E L+E L L ++ I EFL + + K +++ I S++ P +++ + + + ++E F DK G ++ +F VL + + + T++Q+ + L L+ + + FL+ F T F + +D E + +A P + +E VA + ++A S + I + F D ++ + F+ + T ++ L+ +W +N K L +++F + S F +PP L RS + N LR +I + +LL+E D + G IS +F ++++ + ++ E + + K+ NN K AY + ++ K ++ + + G ++ SF+ ++Q I M R+ K D TG +S+A+ R +L ++LSE+E F+++ YDK+L+ I+Y L+
Sbjct: 748 ISAEECLRIFPKKLKESFRDVYSAFFRIDLDRDGIISMHDFHRLLQ-YLQLNMVDLEFERFLSLLGLR-----LSVTLNFREFQNLCEKRPWKSDEAPQRLIRCKQKVADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPREFEKLWQNYDTEGRGYITYQEFLHRLGI------RYSPKVHRPYKEDYFNFLGHFTKPKQVQEEIQELQQISEREKLMNHYEEISKAFNAMEKSKPVALCRVQKVLQECGCPLKEEELISLLKSLDVSVHNNHIDPVEFLRALEISWASKARPK---EKEESSPPPISFSKVTPDEVIK-TMQEVVESSQPALVEAFSALDKEDTGFVKAMEFGDVLRS-VCQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFST--FQDETADDWAEN---MPKAPP--PMSPKETAHRDIVARV----QKAVASHYHTIVQEFENFDTLKSNTVSRD-EFRSICTRHIQI-LTDEQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGDSGESTMAQRGSSAPEFSQGTRSNLYSPPRDSRVGLKSRSHPCTPVGTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEA-----GMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADFRKVLRQYSINLSEEEFFHVLEYYDKSLSSKISYNDFLR 1512
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. UniProt/SwissProt
Match: sp|Q5RE62|EFCB6_PONAB (EF-hand calcium-binding domain-containing protein 6 OS=Pongo abelii OX=9601 GN=EFCAB6 PE=3 SV=1) HSP 1 Score: 70.4774 bits (171), Expect = 6.216e-11 Identity = 77/325 (23.69%), Postives = 140/325 (43.08%), Query Frame = 1
Query: 838 IVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASF----------------IEKLLKTKLREGFTTLRQD----FQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID-SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDT 1749
+ +++ A Y+ K ++R L+ F ++ + + D+KN+LY I L P E EKLW +++ +G I +FL+++G I+Y A P + D F N F EK + R+ L QD F K D ++T ++SI +VL E L E L L+ ++ + I Y +FL ++ G K + ++S I + LNP +V K+ + + L + F DK G ++ +F +VL++ + ++Q+ + L ++ + + FL+ F
Sbjct: 675 VADSELACEQAHQYLVTKAKNRWSDLSKNFLETDNEGNGILRRRDIKNALYGFDIPLTPREFEKLWARYNTEGKGHITYQEFLQKLG-INYSPAVHQP---CAEDYF--NFMGHFTKPQQLQEEMKELQQSTEKAMAA--RDKLMDLHQDISKAFTKIDKSKTNYISICKMQKVLEECGCSLTEGELTHLLNSWGVSRHENAINYLDFLRAVENSKSTGAQPK-----EKEESMPISFATLNPQEVVR-KIQEVVESSQLALSTAFSALDKEDTGFVKATEFGQVLKD-FCYKLMDNQYHYFLRKLRIHLTPYINWKYFLQNFSC 984
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Match: A0A267DVA3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033909g1 PE=4 SV=1) HSP 1 Score: 527.709 bits (1358), Expect = 9.958e-169 Identity = 320/931 (34.37%), Postives = 519/931 (55.75%), Query Frame = 1
Query: 172 IEHPLSKMA---------KENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQS---------------------------RNSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSE-TSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPN-------------------VRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYN--IEEI--QSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKF-KTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMI-------RNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
IEHP++KMA + + T + + + GR LA E P + + SS R RS + N G IPE + VV G++ TR+P+FG R+ + ++S +SR A+ A +L L+EI I++ K+ NYYE+RK+F NDP++KGNV ++AL+RI+ VG ++ L LFE GI+ + Q+++F+E Y+ + +E E ++ DP+ R + + +++A + E+ R R + L D+FP V+ + K +L++SL K+++ + E E+LW +D G+++ + LK++GI P + S +S + +L IE LK K REGF L+ F+ +D +TG +S DF+ VL EH L LE+ +L EFL+RC +T TK G+ Y++FL RFQDRSEAG+ HK++ + + K + S +S +E +L+N+FQ+DFL +L F+K D++ I ++F+ V+E++ E T++Q++ VD LPLN + + Y F++QFDT + F + + V +E+D D + +EE + ++V+E + ++ S+F ++E F ELD +N LT E+M+QL+ +KPE++RG+IR +WKTFIL ++ LD++EF R F++N TA++PNAKL PP KGDSDLM RSRK+N+ ++L D LRAKID L++ L EF +DP G IS E+FQE++KEL+I LTD+E+ +TDKF + + ++ Y+ELL+PF K ++ ++ + + + L A ++ + R + K+D N+G IS+AE R++L L V L E+E F LM+ +D +L+G + YK +L+
Sbjct: 21 IEHPMAKMADRLQTPLDVRGDGRSGTAGDVM---EGGRPLASEQ----PPVQPASAASSRRGRRSQVAASNGGGGGLRHQTIPEGVEVVHGESGRTRLPVFGVRAQDAAEAALDRARQSLDADASPAAAAGDRALLKSSNSSRLSEAQSA-RLELDEIEAIIKEKVRNNYYEMRKRFTANDPEQKGNVTRDALLRILVSAVGRPVSLRQLAQLFERVGIRRDAQLINFSEFYSAL--RDQEPGEYPNWMDPIQRQR---LERNRLSAEQVHANLSERMRQRFVDLADVFPQFVDGGTGRMLKHELRSSLEKMLLPMDDDEFERLWRIYDPRDTGTVNGVSLLKKLGIAMKPAEGGGSHRDAAAKPAAKPAAAATRRPALKSEESRQRSLT---IESWLKDKFREGFQALKAGFEARDPERTGLVSHDDFLAVLREHSLSLEKRHLAEFLARCAVTHTKAGVMYRDFLHRFQDRSEAGMAHKIMANPHHTKEDDTVSRT--LSSIEKQLMNMFQRDFLSLLSAFQKIDRHGLNVISQEEFRAVMESRFGFELTDAQYREFVDKLPLNSDGLIRYDIFMRQFDTKGMAPSLFKSVG-GNDVASESDAARDEDDELEEPYDPNKRSVSETRRCIRDLLHSRFQEVETAFYELDTFNSGRLTQEMMYQLLNRF-IKPEVTRGEIRDLWKTFILGGREALDYQEFLRAFIFNPLTAAYPNAKLAPPRKGDSDLMMRSRKVNSDVNLLEDGLRAKIDYLWDQLRDEFVSMDPYGTGCISREEFQEVLKELAIQLTDYELNRLTDKFTQKSDGRVNYIELLRPFAYKKFGPKRQHMNELLSQRSPAAENGHATGQPVASAELQSLAAKLKRQLTGEWKNLRRQLMKMDPNNSGSISLAEFRSVLKLFNVILDEEESFQLMSHFDTSLSGKLPYKKVLE 931
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Match: A0A267GEM4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033909g3 PE=4 SV=1) HSP 1 Score: 520.776 bits (1340), Expect = 4.577e-166 Identity = 318/939 (33.87%), Postives = 516/939 (54.95%), Query Frame = 1
Query: 172 IEHPLSKMA---------KENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQS---------------------------RNSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSE-TSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPN-----------------------VRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGN-----FSSLSFNDIHETSSV---LNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKF-KTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMI-------RNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
IEHP++KMA + + T + + + GR LA E P + + SS R RS + N G IPE + VV G++ TR+P+FG R+ + ++S +SR A+ A +L L+EI I++ K+ NYYE+RK+F NDP++KGNV ++AL+RI+ VG ++ L LFE GI+ + Q+++F+E Y+ + +E E ++ DP+ R + + +++A + E+ R R + L D+FP V+ + K +L++SL ++++ + E E+LW +D G+++ + LK++GI P + S +S + +L IE LK K REGF L+ F+ +D +TG +S DF+ VL EH L LE+ +L EFL+RC +T TK G+ Y++FL RFQDRSEAG+ HK++ + + K + S +S +E +L+N+FQ+DFL +L F+K D++ I ++F+ V+E++ E T++Q++ VD LPLN + + Y F++QFDT F S+ ND+ S ++ Y+ + ++V+E + ++ S+F ++E F ELD +N LT E+M+QL+ +KPE++RG+IR +WKTFIL ++ LD++EF R F++N TA++PNAKL PP KGDSDLM RSRK+N+ ++L D LRAKID L++ L EF +DP G IS E+FQE++KEL+I LTD+E+ +TDKF + + ++ Y+ELL+PF K ++ ++ + + + L A ++ + R + K+D N+G IS+AE R++L L V L E+E F LM+ +D +L+G + YK +L+
Sbjct: 21 IEHPMAKMADRLQTPLDVRGDGRSGTAGDVM---EGGRPLASEQ----PPVQPASAASSRRGRRSQVAASNGGGGGLRHQTIPEGVEVVHGESGRTRLPVFGVRAQDAAEAALDRARQSLDADASPAAAAGDRALLKSSNSSRLSEAQSA-RLELDEIEAIIKEKVRNNYYEMRKRFTANDPEQKGNVTRDALLRILVSAVGRPVSLRQLAQLFERVGIRRDAQLINFSEFYSAL--RDQEPGEYPNWMDPIQRQR---LERNRLSAEQVHANLSERMRQRFVDLADVFPQFVDGGTGRMLKHELRSSLERMLLPMDDDEFERLWRIYDPRDTGTVNGVSLLKKLGIAMKPAEGGGSHRDAAAKSAAKPAAKPAAAAPRRPALKSEESRQRSLT---IESWLKDKFREGFQALKAGFEARDPERTGLVSHDDFLAVLREHSLSLEKRHLAEFLARCAVTHTKAGVMYRDFLHRFQDRSEAGMAHKIMANPHHTKEDDTVSRT--LSSIEKQLMNMFQRDFLSLLSAFQKIDRHGLNVISQEEFRAVMESRFGFELTDAQYREFVDKLPLNSDGLIRYDIFMRQFDTKGMAPSLFKSVGGNDVASESDAGIDEDDELEEEPYDPNK----RSVSETRRCIRDLLHSRFQEVETAFYELDTFNSGRLTQEMMYQLLNRF-IKPEVTRGEIRDLWKTFILRGREALDYQEFLRAFIFNPLTAAYPNAKLAPPRKGDSDLMMRSRKVNSDVNLLEDGLRAKIDYLWDQLRDEFVSMDPYGTGCISREEFQEVLKELAIQLTDYELNRLTDKFTQKSDGRVNYIELLRPFAYKKFGPKRQHMNELLSQRSPAAENGHATGQPVASAELQSLAAKLKRQLTGEWKNLRRQLMKMDPNNSGSISLAEFRSVLKLFNVILDEEEAFQLMSHFDTSLSGKLPYKKVLE 936
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Match: V4AX16 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_238765 PE=4 SV=1) HSP 1 Score: 515.768 bits (1327), Expect = 1.220e-164 Identity = 319/924 (34.52%), Postives = 516/924 (55.84%), Query Frame = 1
Query: 124 MSRPASVKTAVNKMLA---IEHPLSKMAKENTFDNT-----VNNFLTPADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRN-----STTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIAS------LTPNVRASNDSFKLNLNASF--------------IEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTD---RDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNN-KIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMI-------RNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQD 2763
++RPAS + + ++ I+HPLS+M+ + T + + +GR LA E EQ + K R DN + +IPE + V GD TRMP+FG+R+ + R S R +A +L ++E+ +L+ K++ NY E++K+F DNDP+ KGNV +EAL RI+ I+ +++ S ++ L E +K EK ++SF E ++ F ++++ + DPV R+ M+A+ +KEK + R M L D+ P + I K + + L K+M L E +KLW K+D+ +G I KFLK +GI +++ L+P V N S + ++S IE+ LK K REGF +++ F+ KD +++G +S DF++VL H LKL+++ LG FLSRC + GIPY+EFL RFQDRSE G+ H +L+ R NK S S + +S +E +L+N+FQ+DFL +L F+ DK I L++F+ +E++ N+E T+ QF +D LPL+ + V Y +F+KQFDT + F + P+ + +EE S + EI ++K KF ++EK F +LD+ N + +T E+M+QL+K ++KP +SRG+IR +WKTFI N + LD+ +F RHF ++ +A++PNAK PP GDSD M RSRKLN+ D+L DN+R+KI+LL++DL +EF +D N G I+VE+F++I+ EL+IHL++ E+ +T KF T N+ +++Y+E LKP+ QQ + + + Q +D + H + ++ M R +K+D G++S+ E +++L L V L EDE++++M+ +DK ++G I+Y +Q+
Sbjct: 6 LARPASQMSVMQTRMSLPEIQHPLSRMSNPGNMNVTGVSKSQDRPFSQMSQGRPLANE-EQLFVRKSFSAMGRRESRLRFRK--DNFAQPPPAIDSIPEGVEVSQGDPTKTRMPIFGSRAEMADREDIVPPSRAGRMSAASTQARLEIDELESLLRGKVKNNYREIKKRFKDNDPELKGNVTREALSRILMVILNRQLSQSVISRLLERLHLK-EKSVISFTEFHSAF-RVDEDRNYPKWMDPVTRNDK-----VNMSASQVHTQLKEKAKQRFMDLADMIPQINPGGSGRILKPEFRQMLSKMMFYLEDEEFDKLWNKYDRDCEGVIKGEKFLKALGIQWRGMSAESEKCPLSPVVEQGNPSPESERSSSRTPKRREVERRQQLDIERWLKDKFREGFFNMKESFEVKDIDKSGVVSYDDFLEVLETHGLKLDKTLLGAFLSRCSVKVQGRGIPYREFLHRFQDRSEDGMVHNILSQTKHRFNKPGS--PSNNSTLSAIESQLMNMFQRDFLALLATFKNIDKLGQDRISLEEFRAAVESRFNLELTDGQFDSFIDRLPLDEDGDVIYGEFMKQFDTKGKAQSLFTGKKKVDI------PLQEEYLEEAPSHRHPKEIFKVIKDLLSRKFQEVEKEFYDLDDTNTRRITQEMMYQLLKRFNIKPHVSRGEIRDLWKTFITNSDRTLDYHQFVRHFGFSIRSAAYPNAKYCPPRHGDSDCMVRSRKLNSTRDLLEDNVRSKIELLFDDLRREFQSMDVFNTGFITVEEFKDILLELNIHLSEVELDNITRKFNTRNDGRVSYVEFLKPY--EWKQQTWRH-----GNDMATVLQQPLAEDDGAIS-LHGITNKLREKMSGDWKTLRRAFRKLDLNGNGYLSLPEFKSVLKLANVILDEDEIYHVMSEFDKGMSGKISYDQFIQE 903
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Match: A0A1S3I399 (EF-hand calcium-binding domain-containing protein 6-like OS=Lingula unguis OX=7574 GN=LOC106160635 PE=4 SV=1) HSP 1 Score: 514.227 bits (1323), Expect = 4.975e-164 Identity = 320/927 (34.52%), Postives = 504/927 (54.37%), Query Frame = 1
Query: 124 MSRPASVKTAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADE------GRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGS----AKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGI--------ISYPIASLTPN-------VRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTD---RDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDT-GNFSSLSFNDIHETSSVLNEADPVT-----------DYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKT-PNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXI---DQFNGKDSNSFHFFHKLQAVIQS---AMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQD 2763
+SRPA T K+ I+HPLS+M+ D V F D GR LA E+ P++ S ++ SM L +IPE I + GD + TR+P+FG+R+ + SR SR S +L ++E+ +L+ K + +YE+RK+F DNDP+ KGNV +EAL RII +G ++ + + L E + + ++K ++SF E + IF + + + + DPV+RH + + M A +KEK + R + + DL P S + K + +N+L K+M + E EKLW ++D G+ID K +K++GI + P S P R+ + IE LK K REG +R F+ D TG +S +F+ VL+E LKLE+ +L EFL+R I ++G+ Y+EFL RFQDRSEAG+ HK+L++ R NK + + VS +E +++N+FQ DFL +L F K D+ I ++F+ +E++ ++ T+ QF ++D +PL+ + +V Y +F+ QFDT G SL +T+ P T D + E +T+ +++ ++K +++ ++E F ELDE N + L+ EL +QLMK ++PE++RG+IR +WKTFILN +K LD+ EF RHF YN ASFPNAKL+PP KGDSD M RSRKLN A D+L D+LRAKID ++ DL +E +DP +++++F+EI+ EL +HL+D+E+ ++ KF+T + +I Y+E LKPF K N+ + + ++ D + KL+ + + R KK+D N G++S+ E R++L L V L E+EV+ +M +D+N++G I Y L +
Sbjct: 6 VSRPA---TGFGKLPEIQHPLSRMSNPEKLD--VRGFSRAGDRPASQMNGRPLAAENNY-MSPRRLNTSAGRQSKNQLRHSMPELTHE-----SIPEGIEITHGDPSKTRLPVFGSRAEVASRAEMGSRLASRMSRPGTQARLEIDELEMLLREKSKGGFYELRKRFKDNDPEGKGNVTREALARIIVTFLGRPLSNTQFSRLLERFAL-ADKTVVSFTEFFAIFRDAASSEY-PRWMDPVHRHHQEKVT---MNAAQVHAQLKEKAKQRFLDMADLIPQSNPGGTGRLLKPEFRNALNKMMFFMDDDEFEKLWERYDTEGYGTIDGKKLMKKLGIDLANGTAGKTSPRLSPIPEGGRRSGMARSPRKKEADRQRSLGIENWLKNKFREGCQNMRVAFETYDEKNTGMVSAENFLTVLNEFGLKLEKPHLEEFLARANIELQRQGVKYREFLHRFQDRSEAGMPHKILSNPKHRYNKSRAGSAGGKSTVSALEAQIMNMFQTDFLALLGTFHKIDRMGTDQISQEEFRAAIESRFSLNMTDLQFNNLIDKVPLSEDGSVKYAEFMSQFDTRGKAPSL----FEKTAGEPQMPKPNTKVDRLVVQEPMDIDSEVEYKHRTIPQLQKMIKDLLHNRYAEVESAFYELDESNNQRLSQELFYQLMKKF-IEPEITRGEIRELWKTFILNTRKTLDYLEFVRHFGYNAKDASFPNAKLSPPKKGDSDFMMRSRKLNCAADMLQDSLRAKIDYMWEDLRRELVDMDPYATQFVTIDEFREILTELCVHLSDYELDMLCKKFETKKDGRINYVEFLKPFALKKQVWRHGNNMLSLLQHPAAELPIADIVENPEKGLTGLTAKLRQKLSGDWKNLRRTFKKLDVNNEGYLSVPEFRSVLKLANVVLDEEEVYQVMQKFDENMSGKIPYNKFLSE 911
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Match: K1PYF0 (EF-hand calcium-binding domain-containing protein 6 OS=Crassostrea gigas OX=29159 GN=CGI_10014601 PE=4 SV=1) HSP 1 Score: 511.916 bits (1317), Expect = 1.337e-162 Identity = 317/958 (33.09%), Postives = 515/958 (53.76%), Query Frame = 1
Query: 124 MSRPASVKTAVNKMLA-IEHPLSKMAKENTFD-----NTVNNFLT-PADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSR-------NSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKA-KAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGII------------------------------SYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNID------SELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFN-----DIHET----SSVLNEADPVTDYNIEEI-----------QSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXI---DQFNGKDSNSFHFFHKLQAVIQS---AMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQD 2763
+ RPAS+ + L IEHPLS+M D + + L+ PA GR LA +E Y +KS+ + S M + +IPE + V GD TR+P+FG+R+++ SR + +SR +L ++EI +L+ +++ +YYE++KKF DNDP++KGNV +EA RI+ I+ ++ + N L + G K +KQ+++++E + F + + DPV R KAI MT++ +KEK R + + + DL P I K + K L K+M + E EKLW K+D G+++ +FL +GI P ++ TP R K +L+ IE+ LK K REG +++ F+ KD +G +S F++VL+++ LKLE+ L FLSRC + ++G+PY++FL RFQDRSE G+TH +LT+ ++ ++ S+++ +S +E +++N+FQ+DFL +L F+ DK I ++F+ +E++ N + QF VD LPL+ + + Y DF++QFDT + F D+ S +L + P D ++ + Q ++ E+ ++K + +F DIE+ F ELDE N + L+ E+MFQL+K D++PE+SRG+IR +WKTFI N K LD+ EF RHF ++K +ASFPNAK+NPP +GD+D M RSRKLN A D+L D+LR+K+D ++ DL KEF +DP G IS E+F++++ EL +HL++ EI ++DKF + +++Y+E LKPF K N+ ++ D KL+ + + R +K+D+ N G++S+ E R++L L V L EDEV++++ +D N++G I Y+ +++
Sbjct: 6 IPRPASMGQKMGVSLPQIEHPLSRMGNPTNMDIRGVSRSGDRPLSHPA--GRPLA--NENVYSGRKSVSAYGRDSRLGSRQMMQA----PLPIDSIPEGVEVTYGDPAKTRLPVFGSRADVGSRMDNGAPPSRMSSRLSQVSTQARLEIDEIETMLKQRIKGSYYEIKKKFKDNDPEQKGNVSREAFYRILMTILNRNVSQNVFNRLMDRLGFK-DKQIINYSEFFAYFHEAQAQNDYPRWMDPVQRMWPDKAI----MTSSQVHAQLKEKVRQKFLDIADLIPQMNPGGTGRILKPEFKQMLNKLMFYMEDTEFEKLWKKYDPNNSGTVNGAQFLNALGIQMENGGEERQASPQLITGKDAKKVAKKVTLKEGPSSNRTP--RKKEIERKQSLD---IERWLKNKFREGCHQMQEAFEAKDPTNSGVVSFDVFLEVLAQYHLKLEKKLLAAFLSRCAVQARRDGVPYRDFLHRFQDRSEVGMTHNILTNTKHRLVRLVNDRPASPSQVSTMSGIEVQVMNMFQRDFLALLGTFKSIDKLGLNVISQEEFRAAIESRFNFHLQDDQFDAFVDRLPLDEDGNIKYADFMQQFDTKGKAKSLFEKQPGVDLSGPPKVPSPILEVSPPEADEGVDRLVVDEPVFADYAQVRRSPQELFKVIKDLMNRRFQDIERVFYELDEINSERLSQEMMFQLLKRFDIRPEVSRGEIRDLWKTFITNTDKTLDYNEFVRHFGFSKKSASFPNAKMNPPKRGDADFMIRSRKLNCAADMLEDSLRSKVDYMWEDLRKEFVEMDPYGTGFISREEFKDVLTELCVHLSEFEINKLSDKFDLKRDGRVSYIEFLKPFALRKQIWRHGNNMLSLLAHPQPELPIHDIVEPPQKGLHGITSKLRQKLAGDWKNLRRAFRKLDTRNEGYLSVPEFRSVLKLANVILDEDEVYHVLTQFDHNMSGKIPYEKFIEE 945
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Cavefish
Match: si:dkey-256e7.5 (si:dkey-256e7.5 [Source:ZFIN;Acc:ZDB-GENE-090313-282]) HSP 1 Score: 166.392 bits (420), Expect = 3.106e-45 Identity = 92/305 (30.16%), Postives = 169/305 (55.41%), Query Frame = 1
Query: 1870 IKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQ--------QILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ +++ + D+ K F ELDE N + LT E M+QL+K V E++RG++R +W + + + ++F+ F RHF + ++ +PNAK PP +GD+DLM+ S+ L+ +DIL+D+LRAK++L +L EFT +D G++S E+F+E++ L + L +E ++ +KF N+ ++Y E L+PF S + L + + + ++ +N K + I+ A +++D+ + G +S AEL +L L GV S +E+ ++++ + G ++Y+ LLQ
Sbjct: 7 LSKLIRNTVAQHYRDVVKVFEELDEKNTRRLTQEDMYQLLK-FPVLSEITRGEVRHLWSSLLTRQDGTVEFEHFIRHFGPSPTSRRYPNAKRCPPKRGDNDLMRLSKNLSYVSDILVDSLRAKVELSVAELWAEFTSMDMLGTGSVSREEFKEVLTSLCVLLNQYECEVLANKFDLNNDGVSYREFLRPFASQGQEWTNGFNMAAALHSHRETGDSPRNMEVVSLETLSTNIRKRLGKKRRAIRKA----CQRLDASSCGHLSAAELVTVLQLCGVCKSPEELKSVISVLSTDPTGHLDYRPLLQ 306
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004536.1 (pep scaffold:Pmarinus_7.0:GL477109:94389:131012:-1 gene:ENSPMAG00000004110.1 transcript:ENSPMAT00000004536.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 125.561 bits (314), Expect = 1.850e-29 Identity = 167/809 (20.64%), Postives = 322/809 (39.80%), Query Frame = 1
Query: 529 EEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLK-FDQTKQGSIDSMKFLKQIGIISYP------------------IASLTPNVR----------ASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQK--DFLEILEN-FRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETS-SVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLL---DFKEFTRHFMYNKS------TASFPNAK--LNPP---------------VKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKT-PNNKIAYLELLKPFC---SHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQS--AMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
E+ L +KL + Y ++R F D DR G V L R+++ + +T L M G+ +E+ LS+ + F ++E E + + R + P++M A Y+ + R ++ F D E+ + K++L+ L++ M+ L + + LW + +D G I + + + + P +A+L R A +F N + + +K K R+ ++ F + D ++ GF++ D +L EH+ L+ + L + I + Y +FL D G + N L+P E L L +K L +L+ F FDK Q G ++ ++F++VL+N ++ QF+ ++ L + TV + DFL+ F + + + E + + L D+ + +G + ++ ++ ++F + + D LT E Q++ ++ LS +W ++E L D++EF + F + T+S P A PP V+G + RS L + L LR ++ + ++L+E DP +G I D +++ + L++ E+ + KF +AY L+ + +L+ ++ D+ H + V+ + M R + +D +GF+S + R +L ++L+EDE F ++N YD L+ + Y L+
Sbjct: 750 EDCHAALPDKLRQVYTDLRSAFNKADGDRDGAVTAGDLRRLLETL-HFSLTDGEFGRLLGMLGL-NERSRLSYGDFLQTFDPPTQE-GEPRWLEAGAR-IMEIKDPSEMACEQAHQYLVSRARKSWKDVSQAFRDYDENGDRVVQKSELRTLLFRYMLPLTSHDFDSLWARRYDPDGHGVISEQELAQLLDVARPPTGVDKGPSARIAEQNQATLATLAEGQRERRCELAGQQARRGAF---YNLEQLAQEIKDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLRAVDD----GRASRYGVRPSKPCGGNATQRLSP----EGALAFLREKVPSLLAVLQKAFSAFDKSQRGLVKEEEFRRVLDN-FCLKLDGPQFQHLLKRLKRGGDGTVDWQDFLEAFSLLSDKTEGADWQREVARAALAGHRGAGDH---ALSAGGVLRRLRDVVS----ARFYAVARALVCADLPGVGRLTREQFRQVVHRHFLR--LSDKQFEELWAQLPVDECDKLDYRDYREFLKRFCDGTALPAAAFTSSAPPALGIYKPPQSLNTGHRPASVAGSVRGGTARAVRSTPL-VDCEALESRLRERVSRRWQEILRECRLKDPTASGEIGANDLLGVLRTFDVWLSEDELAGLASKFAAHSTGHVAYRAFLRHLVLTLRPRQHGLLQRQRLQQPSFTPGGTAP---NDAFLEAMLHLREQVLPNWRPMRRAFRAVDPSASGFLSAPDFRQVLKQFAINLTEDEFFQILNYYDGQLHNRVPYNAFLR 1529 HSP 2 Score: 78.1814 bits (191), Expect = 6.540e-15 Identity = 137/712 (19.24%), Postives = 270/712 (37.92%), Query Frame = 1
Query: 523 SLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDP---------------VNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFS-ITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYP--IASLTPNVRASNDSFKLNLNASFIEKL----------------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSK-----------FGDIEKRFNELDEYNGKVLTPE----LMFQLMKTLDVKPELSRGDIRSVWKT-------FILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAAT-----------DILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP--NNKIAYLELLK 2433
S E+ L+ + + Y +++ F+ D +R+G V ++ L R+++ F M + ML + ++ FV+ + F+P VN HK I +T A + +++K R + + F DS + A IT+ +L+ L + L KL +Q I +FL ++G+ P A ++ + + +++ ++ A +L L+ + + TTL Q F + D G +S DF Q+L E + +E+ L R + T I Y +F+ F DR G +LL N + + + + L + ++ + ++ F K D ++G++ D +++LE ++ T+ +F ++ L LN + Y DFL+ FD P + +++G + EIK + A + + D+ + F + DE +V+ L+F+ M L+ D S+W +++E++L + R S A+ N QR R+ A + L ++ K Y+D F D + +G ++ +D + ++ E + L + + K P ++++Y + L+
Sbjct: 405 SASEVLARLRKHILECYPSLKEAFLALDINRQGRVTRQELRRLVEGFG------------FRMGDGHFRELMLLLDPGHSGFVDYT---DFLCLFEPRETLDAHKWLNSTHRVNGHKTTDI----LTWKAAEEILRDKLTERWKDVCEAF-DSCDQDADGFITQDNLRAILRRFGPSLSDEHFNKLCTGCEQGPGFRILFSEFLLRLGVDPRPGDFAGVSSRLHSESNAREVKRQADLSARLELIEGEARKLTGALPLREVLVRLRDHVAQRDTTLHQSFARHDRRGEGRVSHFDFRQILQECGMIMEDDQFNALLQR--LGFTNGSITYSDFVACFDDRRIHGPGEQLLLS-PNHRVAEASRQHSRAEDCHAALPDKLRQVYTDLRSAFNKADGDRDGAVTAGDLRRLLET-LHFSLTDGEFGRLLGMLGLNERSRLSYGDFLQTFDP----------------------PTQEGEPRWLEAGARIMEIKDPSEMACEQAHQYLVSRARKSWKDVSQAFRDYDENGDRVVQKSELRTLLFRYMLP------LTSHDFDSLWARRYDPDGHGVISEQELAQLLDVARPPTGVDKGPSARIAEQNQATLATLAEGQRERRCELAGQQARRGAFYNLEQLAQEIKDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLR 1064 HSP 3 Score: 66.2402 bits (160), Expect = 2.943e-11 Identity = 116/570 (20.35%), Postives = 218/570 (38.25%), Query Frame = 1
Query: 1120 SLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEG-IPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQF------------DTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMK--TLDVKPE-----LSRGDIRSV----WKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLN---------AATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTD---HEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKI-------DSGNTGFISIAELRALLLLEGVSLSEDEVFN 2700
+LTP+V S K L+AS + +L++ + E L + F+ D + G +S + +VL L L + G S ++ + G IPY +FL F + T I+ E + L +D ++ FR FD +G ++ + + VLE+ +ESQF + +++ TV Y +FL+ DT L E + + P Y I + ++ +++ +G++++ F D L E +++ TL + PE L++ I++ W+ F+ A FPN + G + M+ S ++N +A+++L LR I Y L + F LD G ++ ++ + +++ + D E+ ++ D + + Y + L C + ++ L+ + + NG + + + +++ + K + D GFI+ LRA+L G SLS DE FN
Sbjct: 48 ALTPSVALSP---KPALSASEVAELVRHGVEERTEQLVRAFRALDPGRAGTVSHGELRRVLDLFVLPLTDPQFGALFS--MVPAGRNGNIPYLQFLEHFLGQPTRPSTASSRQKSTPPAGRGINEE------TDLLLRKKLGRDLKGVVRTFRLFDYNGDGRVQRHELRGVLESH-GARLSESQFSKLWARHDVHQGGTVAYQEFLESLGLSQESQWHPEPDTVQLCMLHARHRWEHTQPSCHSRPYEIYEISVKGYCLNIVSTESAVQRIVCENYGNLQRAFRAFDGSGSGTLAVEDFVSVLRSFTLPLAPEAMLRVLTQLGIKATGKVPWELFL----------------------AKFPNPQ--SIGNGQTLPMRSSHRVNPFRGADESTSASEVLA-RLRKHILECYPSLKEAFLALDINRQGRVTRQELRRLVEGFGFRMGDGHFRELMLLLDPGHS--GFVDYTDFL---CLFEPRETLD------AHKWLNSTHRVNGHKTTDILTWKAAEEILRDKLTERWKDVCEAFDSCDQDADGFITQDNLRAILRRFGPSLS-DEHFN 568
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004547.1 (pep scaffold:Pmarinus_7.0:GL477109:94389:129511:-1 gene:ENSPMAG00000004110.1 transcript:ENSPMAT00000004547.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.168 bits (300), Expect = 9.451e-28 Identity = 163/809 (20.15%), Postives = 319/809 (39.43%), Query Frame = 1
Query: 529 EEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLK-FDQTKQGSIDSMKF-----LKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLL----------KTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQK--DFLEILEN-FRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETS-SVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFM--YNKSTASFPNAKLN---PPVKGDSDLMQRSR----------------------KLNAAT------------DILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKT-PNNKIAYLELLKPFC---SHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQS--AMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
E+ L +KL + Y ++R F D DR G V L R+++ + +T L M G+ +E+ LS+ + F ++E E + + R + P++M A Y+ + R ++ F D E+ + K++L+ L++ M+ L + + LW + +D G I + ++Q + NV + L IE++ + K R+ ++ F + D ++ GF++ D +L EH+ L+ + L + I + Y +FL D G + N L+P E L L +K L +L+ F FDK Q G ++ ++F++VL+N ++ QF+ ++ L + TV + DFL+ F + + + E + + L D+ + +G + ++ ++ ++F + + D LT E Q++ ++ LS +W ++E LD++++ R F+ + TA P A PP G + + R + L+ T + L LR ++ + ++L+E DP +G I D +++ + L++ E+ + KF +AY L+ + +L+ ++ D+ H + V+ + M R + +D +GF+S + R +L ++L+EDE F ++N YD L+ + Y L+
Sbjct: 689 EDCHAALPDKLRQVYTDLRSAFNKADGDRDGAVTAGDLRRLLETL-HFSLTDGEFGRLLGMLGL-NERSRLSYGDFLQTFDPPTQE-GEPRWLEAGAR-IMEIKDPSEMACEQAHQYLVSRARKSWKDVSQAFRDYDENGDRVVQKSELRTLLFRYMLPLTSHDFDSLWARRYDPDGHGVISEQELAQLLDVQQSSTCLLQCNGIYCNVMKGCTKKQCPLIMGRIEEMSFSLSLSSSFHRDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLRAVDD----GRASRYGVRPSKPCGGNATQRLSP----EGALAFLREKVPSLLAVLQKAFSAFDKSQRGLVKEEEFRRVLDN-FCLKLDGPQFQHLLKRLKRGGDGTVDWQDFLEAFSLLSDKTEGADWQREVARAALAGHRGAGDH---ALSAGGVLRRLRDVVS----ARFYAVARALVCADLPGVGRLTREQFRQVVHRHFLR--LSDKQFEELWAQLPVDECDKLDYRDY-REFLKRFCDGTA-LPAAAFTSSAPPDNGATAMKSRPKTTASCLLTRSEHTHGHAQSTHPSLSGGTARAVRSTPLVDCEALESRLRERVSRRWQEILRECRLKDPTASGEIGANDLLGVLRTFDVWLSEDELAGLASKFAAHSTGHVAYRAFLRHLVLTLRPRQHGLLQRQRLQQPSFTPGGTAP---NDAFLEAMLHLREQVLPNWRPMRRAFRAVDPSASGFLSAPDFRQVLKQFAINLTEDEFFQILNYYDGQLHNRVPYNAFLR 1470 HSP 2 Score: 83.1889 bits (204), Expect = 2.169e-16 Identity = 136/696 (19.54%), Postives = 274/696 (39.37%), Query Frame = 1
Query: 523 SLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSK-----EKSET--SFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFS-ITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYP--IASLTPNVRASNDSFKLNLNASFIEKL----------------------LKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDS-----------KFGDIEKRFNELDEYNGKVLTPE----LMFQLMKTLDVKPELSRGDIRSVWKT-------FILNEK---KLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP--NNKIAYLELLK 2433
S E+ L+ + + Y +++ F+ D +R+G V ++ L R+++ F M + ML + ++ FV+ + E ET VN HK I +T A + +++K R + + F DS + A IT+ +L+ L + L KL +Q I +FL ++G+ P A ++ + + +++ ++ A +L L+ + + TTL Q F + D G +S DF Q+L E + +E+ L R + T I Y +F+ F DR G +LL N + + + + L + ++ + ++ F K D ++G++ D +++LE ++ T+ +F ++ L LN + Y DFL+ FD P + +++G + EIK + A + + D+ + F + DE +V+ L+F+ M L+ D S+W +++E+ +LLD ++ + + + + N K +M R +++ + + R K Y+D F D + +G ++ +D + ++ E + L + + K P ++++Y + L+
Sbjct: 349 SASEVLARLRKHILECYPSLKEAFLALDINRQGRVTRQELRRLVEGFG------------FRMGDGHFRELMLLLDPGHSGFVDYTDFLCLFEPRETLVGLTHRVNGHKTTDI----LTWKAAEEILRDKLTERWKDVCEAF-DSCDQDADGFITQDNLRAILRRFGPSLSDEHFNKLCTGCEQGPGFRILFSEFLLRLGVDPRPGDFAGVSSRLHSESNAREVKRQADLSARLELIEGEARKLTGALPLREVLVRLRDHVAQRDTTLHQSFARHDRRGEGRVSHFDFRQILQECGMIMEDDQFNALLQR--LGFTNGSITYSDFVACFDDRRIHGPGEQLLLS-PNHRVAEASRQHSRAEDCHAALPDKLRQVYTDLRSAFNKADGDRDGAVTAGDLRRLLET-LHFSLTDGEFGRLLGMLGLNERSRLSYGDFLQTFDP----------------------PTQEGEPRWLEAGARIMEIKDPSEMACEQAHQYLVSRARKSWKDVSQAFRDYDENGDRVVQKSELRTLLFRYMLP------LTSHDFDSLWARRYDPDGHGVISEQELAQLLDVQQSSTCLL--QCNGIYCNVMKGCTKKQCPLIMGRIEEMSFSLSLSSSFHRDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLR 993 HSP 3 Score: 54.299 bits (129), Expect = 1.681e-7 Identity = 113/564 (20.04%), Postives = 211/564 (37.41%), Query Frame = 1
Query: 1168 LNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCII-TPTKEG--IPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQF------------DTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSG--------KTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMK--TLDVKPE-----LSRGDIRSV----WKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLN---------AATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTD---HEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKI-------DSGNTGFISIAELRALLLLEGVSLSEDEVFN 2700
L+AS + +L++ + E L + F+ D + G +S + +VL L L + G C+I P IPY +FL F + T I+ E + L +D ++ FR FD +G ++ + + VLE+ +ESQF + +++ TV Y +FL+ DT L E + N V D+ +QS ++ + T+++ +G++++ F D L E +++ TL + PE L++ I++ W+ F+ A FPN + G + M+ S ++N +A+++L LR I Y L + F LD G ++ ++ + +++ + D E+ ++ D P + +++ C + ++ L + NG + + + +++ + K + D GFI+ LRA+L G SLS DE FN
Sbjct: 3 LSASEVAELVRHGVEERTEQLVRAFRALDPGRAGTVSHGELRRVLDLFVLPLTDPQFGA----CVIQVPAGRNGNIPYLQFLEHFLGQPTRPSTASSRQKSTPPAGRGINEE------TDLLLRKKLGRDLKGVVRTFRLFDYNGDGRVQRHELRGVLESH-GARLSESQFSKLWARHDVHQGGTVAYQEFLESLGLSQESQWHPEPDTVQLCMLHARHRWEHTQPFN----VKDHTRLGLQSSISIKKQHKVSIHQNSTVLQVC--ENYGNLQRAFRAFDGSGSGTLAVEDFVSVLRSFTLPLAPEAMLRVLTQLGIKATGKVPWELFL----------------------AKFPNPQ--SIGNGQTLPMRSSHRVNPFRGADESTSASEVLA-RLRKHILECYPSLKEAFLALDINRQGRVTRQELRRLVEGFGFRMGDGHFRELMLLLD----PGHS-GFVDYTDFLCLFEPRETLVGL-----------THRVNGHKTTDILTWKAAEEILRDKLTERWKDVCEAFDSCDQDADGFITQDNLRAILRRFGPSLS-DEHFN 507
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004557.1 (pep scaffold:Pmarinus_7.0:GL477109:94389:108111:-1 gene:ENSPMAG00000004110.1 transcript:ENSPMAT00000004557.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 100.523 bits (249), Expect = 5.209e-22 Identity = 132/665 (19.85%), Postives = 260/665 (39.10%), Query Frame = 1
Query: 958 ITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKF-----LKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLL----------KTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEF---KLVNLFQKDFLEILEN-FRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETS-SVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLL---DFKEFTRHFM-----------------------YNKSTA---SFPNAKLN---------PPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKT-PNNKIAYLELLKPFC---SHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQS--AMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQ 2760
+ K++L+ L++ M+ L + + LW ++D G I + ++Q + NV + L IE++ + K R+ ++ F + D ++ GF++ D +L EH+ L+ + L + I + Y +FL D G + N L+P + F K+ +L L +L+ F FDK Q G ++ ++F++VL+N ++ QF+ ++ L + TV + DFL+ F + + + E + + L D+ + +G + ++ ++ ++F + + D LT E Q++ ++ LS +W ++E L D++EF + F + +ST SFP LN V+G + RS L + L LR ++ + ++L+E DP +G I D +++ + L++ E+ + KF +AY L+ + +L+ ++ D+ H + V+ + M R + +D +GF+S + R +L ++L+EDE F ++N YD L+ + Y L+
Sbjct: 12 VQKSELRTLLFRYMLPLTSHDFDSLWARYDPDGHGVISEQELAQLLDVQQSSTCLLQCNGIYCNVMKGCTKKQCPLIMGRIEEMSFSLSLSSSFHRDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLRAVDD----GRASRYGVRPSKPCGGNATQRLSPEGALAFLREKVPSL-----LAVLQKAFSAFDKSQRGLVKEEEFRRVLDN-FCLKLDGPQFQHLLKRLKRGGDGTVDWQDFLEAFSLLSDKTEGADWQREVARAALAGHRGAGDH---ALSAGGVLRRLRDVVS----ARFYAVARALVCADLPGVGRLTREQFRQVVHRHFLR--LSDKQFEELWAQLPVDECDKLDYRDYREFLKRFCDGTALPAAAFTSSAPPGIEHTHGHAQSTHPSLSFPPQSLNTGHRPASVAGSVRGGTARAVRSTPL-VDCEALESRLRERVSRRWQEILRECRLKDPTASGEIGANDLLGVLRTFDVWLSEDELAGLASKFAAHSTGHVAYRAFLRHLVLTLRPRQHGLLQRQRLQQPSFTPGGTAP---NDAFLEAMLHLREQVLPNWRPMRRAFRAVDPSASGFLSAPDFRQVLKQFAINLTEDEFFQILNYYDGQLHNRVPYNAFLR 653 HSP 2 Score: 63.5438 bits (153), Expect = 1.539e-10 Identity = 110/572 (19.23%), Postives = 228/572 (39.86%), Query Frame = 1
Query: 883 KEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGS-IDSMKFLKQI--GIIS-YPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEG-IPYKEFLIRFQ---DRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLD---FLKQFDTGN------FSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMK---------------QAFDSKFGD-IEKRFNEL--------DEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSR--------KLNAATDILMD---NLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPF 2439
++KFR + F + + +T+ DL++ L + L + E+L K +GS + FL+ + G S Y + P N + +L+ + L+ K+ L++ F D +Q G + +F +VL LKL+ L R + +G + +++FL F D++E + + V +L ++ F + D G + + F++V+ + ++ QF+ + LP++ + Y D FLK+F G F+S + I T P + + + +G A + ++ +A +S+ + + +R+ E+ +G++ +L+ +++T DV LS ++ + F + + ++ F RH + L P G L+QR R A D ++ +LR ++ + + + F +DP +G +S DF++++K+ +I+LT+ E + + + +N++ Y L+ F
Sbjct: 107 RDKFRDKYSDFGAAFARADRDKDGFVTEDDLRHMLCEHNYSLDREQFEQLLGKLGIPTEGSRLSYADFLRAVDDGRASRYGVRPSKPC--GGNATQRLSPEGALA--FLREKVPSLLAVLQKAFSAFDKSQRGLVKEEEFRRVLDNFCLKLDGPQFQHLLKR--LKRGGDGTVDWQDFLEAFSLLSDKTEGADWQREVARAALAGHRGAGDHALSAGGVLRRLRDVVSARFYAVARALVCADLPGVGRLTREQFRQVVHRHF-LRLSDKQFEELWAQLPVDECDKLDYRDYREFLKRFCDGTALPAAAFTSSAPPGIEHTHGHAQSTHPSLSFPPQSLNTGHRPASVAGSVRGGTARAVRSTPLVDCEALESRLRERVSRRWQEILRECRLKDPTASGEIGANDLL-GVLRTFDV--WLSEDELAGLASKFAAHSTGHVAYRAFLRHLVLT----------LRPRQHG---LLQRQRLQQPSFTPGGTAPNDAFLEAMLHLREQVLPNWRPMRRAFRAVDPSASGFLSAPDFRQVLKQFAINLTEDEFFQILNYYDGQLHNRVPYNAFLRTF 655
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Match: EDO46548 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ2]) HSP 1 Score: 418.698 bits (1075), Expect = 1.240e-131 Identity = 284/921 (30.84%), Postives = 487/921 (52.88%), Query Frame = 1
Query: 148 TAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKP----KKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGG-DANLTRMPLFGNRSNIQSR-NSTTSR----HGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFD---PVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYP--IASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLE-ESNLGEFLSRCIITPTKEG-IPYKEFLIRFQDRSEAGITHKLLTDRDNK-KSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEI----------------------QSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPN-NKIAYLELLKPFCSHKSQQILENXXXXXXXXXXX-XIDQFNGKDSNSFH-FFHKLQAVIQSA---MIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQS 2772
A + AI+HPLS+M + + P R E K +P + SS + D+LNL NIPE I V D + +P+FG+R+++ SR S SR S++ K S++E +L+ K++ Y+ ++ F DP+ KG V +E+L +I+ VG I+ S N L + K+M++++E Y F K ++ + P R MTA+ ++KEK + R + + +L P + I + +L+N L ++ + E EKLWLK+D G+I + K + ++GI P + + R K+ L+ IE+ LK K REGF+ ++ F + D ++TG + DF +VL+E DLKL + + +FL+RC +T T + +PYKEFL RFQDRS+ G+ HK+L ++ ++ S+ S+ + S VE +L++LFQ+DFL +L F D+ G + + F+ +E + + ++ +++ + +P+N + V Y++F+ +FDT F + N + + SSVL +P+ +E Q G++ E+K ++K + F D E+ F +LDE N K LTPE+M +L+K DV +++R +I+ +W TFI +++ L++ +F RHF Y+ +A+FPNAK++PP +GD+D M RS KLN+ D+L D L++K+D ++ L EF DP N G +S E F+EI+++L I LTD+E+ VT+KF N N+++Y++ L+P+ + + N ++ +D K + KL+ + + + +K+D N G++SI E R++L L L EDE+++L++ D ++G++NY+ L + S
Sbjct: 2 AATTNLPAIQHPLSRMGNPANLNVRGTSRDGPRVASRQSLNLGESKLRPITADQMPWRLTKSSNGHNQRSPRDDLNL-----GNIPEGIEVRRAEDPSKPTIPIFGDRADMASRVESRMSRLSSAAASSRGPDKASVDEFEYLLREKMKTGYFTIKNLFKQRDPENKGIVSRESLSQILTTFVGKPISLSQFNKLMVRLNL-DHKKMIAYDEFYAAFRPPKKADEGPAWLELEKPNMR---------TMTASQVHAHLKEKAKQRFLDVAELIPQMNPGGSGRILRPELRNVLNQMGFYMDDDEFEKLWLKYDTENVGTIRAEKLMGKLGISIKPGSTGDMPRSPRKLEVERKVQLD---IERWLKRKFREGFSDMKHAFMELDLDRTGRVRKDDFRKVLAEFDLKLSTDKQVEDFLARCGVTLTSDDLVPYKEFLRRFQDRSQDGMPHKILANQLHRYHHSDQGSQFSTTSAVEARLMDLFQRDFLALLGTFHNIDRKDCGLLTQQQFRAAIEGRFELGMSDEEYEDFLTRVPINNDGMVKYVEFMSKFDT-TFDRDN-NSLFDRSSVLGAPEPMPPIREKESPPGSPRKHRRPRPVKTVDSYDSQDGRSAEELKRVIKNVLVNNFQDFEQAFYDLDELNSKRLTPEMMRKLLKKFDV--DVNRNEIKKLWDTFITDQRGHLEYLQFVRHFGYSIGSAAFPNAKVSPPKRGDNDFMMRSNKLNSDVDMLFDQLKSKVDFHWDRLRGEFAAADPNNAGFVSREAFKEILQDLCIELTDYELSYVTNKFDPKNENRVSYVKFLEPYAKRRRRYFSNNMGTVMNHPQAELPMDDIVPKPNKGLSGITAKLRQKLSGEWKNLRKAFRKLDLQNDGYLSIPEFRSVLRLCNTVLEEDEIYHLLSELDSGMSGNVNYREFLTKVSS 900
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Match: EDO36810 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHJ6]) HSP 1 Score: 142.124 bits (357), Expect = 2.535e-35 Identity = 120/499 (24.05%), Postives = 224/499 (44.89%), Query Frame = 1
Query: 442 LFGNRSNIQSRNSTTSRHGSAKEAV-KLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNR------------------------------HKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIIS----------YPIA---------SLTPNVRASNDSFKLNLNASF---------IEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLV--EFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVI---VDNLPLNRNQTVPYLDFLKQFD 1746
G + Q +N + GS+ +++ + ++EE+ E++++KL ++ VR+ F NDP +G+V +EA I+ + G ++ S ++SL + G++S +SF++ + F + E + + DPV R + +P TA F +K K + PDS + K L+ +L+ + I + E +K+W + D++ G++DS F +G+ PI S+ P A DS K + + I +L K +EG+ + + F + D TG +S + QVL+ + L L + FLSR E +PY++ L QDR++ G+ K++ D ++ + + DS++ + V E +L++L DFL +L F+ D+ G ++ FK++LE + + + Q I + + P + VPY FL++F+
Sbjct: 14 FIGPKQRGQEKNLGRTDGGSSTQSLTRRTVEELEELIKDKLTTGFFGVRQAFRANDPRGRGSVSREAFTTILYHLCG-YVSPSLVSSLLQRIGVESPSS-ISFDDFISHF--RDNEVVQKEWLDPVLRPVRQGAHLPANQLRDSQRERSNVEQHEKRKQGLRKTLPVFYTALQVFPLLKRKAQGGLGEFARFLPDSCFDVDGMVLKPQLRQALFLMDIHMYDDEFDKVWDRIDRSGLGTVDSRTFFLTLGLGGNEGKEKQHQKSPIKEQVLEDKPDSVQPASCAKQDSPKTVIPVTVDECQEEKEDIMAVLSNKFKEGYNGIVEMFSRYDPENTGKVSKHELRQVLASYRLTLGPIEVEHFLSR-FGCRHDEMVPYRKILDMCQDRTDKGLLQKIMEDPKHRFNKSRDSQIGTTTAVDAEARLLDLLHSDFLSLLGAFKSLDRENMGVVKKYQFKELLEARFGIRLNKEQLAAIRLRIGDDPA--SGLVPYPRFLEEFN 505
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Match: EDO28675 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T5T7]) HSP 1 Score: 119.398 bits (298), Expect = 1.174e-27 Identity = 64/176 (36.36%), Postives = 111/176 (63.07%), Query Frame = 1
Query: 1183 IEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLE-ESNLGEFLSRCIITPTKEG-IPYKEFLIRFQDRSEAGITHKLLTDRDNK-KSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLN 1701
IE+ LK K REGF+ ++ F + D ++TG + DF +VL+E DLKL + + +FL+RC +T T + +PYKEFL RFQDRS+ G+ HK+L ++ ++ S+ S+ + S VE +L++LFQ+DFL +L F D+ G + + F+ +E + + ++ +++ + +P+N
Sbjct: 472 IERWLKRKFREGFSDMKHAFMELDLDRTGRVRKDDFRKVLAEFDLKLSTDKQVEDFLARCGVTLTSDDLVPYKEFLRRFQDRSQDGMPHKILANQLHRYHHSDQGSQFSTTSAVEARLMDLFQRDFLALLGTFHNIDRKDCGLLTQQQFRAAIEGRFELGMSDEEYEDFLTRVPIN 647
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Match: EDO28210 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T743]) HSP 1 Score: 85.1149 bits (209), Expect = 2.675e-17 Identity = 85/356 (23.88%), Postives = 158/356 (44.38%), Query Frame = 1
Query: 772 NKSKEKSETSFFDPVN--RHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQG-SIDSMKFLKQIGIISYP-------------------IASLTPNVR-----ASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQK---DFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNL-PLNRNQTVPYLDFLKQFD 1746
N++K E SF D R K + A + A FDY ++ I + +L+ + L + ++LW K+D T+ G ++D M FLK++G+ ++P + L N R +S D + +E+ L+ K+ E F +++ F D GF+++ ++L+ + +S + + RC I + + I Y++FL +FQD +G + ++K + ++E P + +K LF K F + + F FD ++G I +DF+++LE+ TE QF ++ + P+NR + YL+FL +F+
Sbjct: 2 NQTKSPKEQSFADIEQQLRTKIAGQLQAVLKAIRLFDYNRDG---------------------QIQRHELRRVVENFCFRLTNEQFDRLWCKYDLTRNGHTLDYMDFLKRLGVNTHPKRRPSTANRLNQGNGTENKVKFLATNKRPLSGSSSRDGSPAVMTVKDLERKLRAKMVENFENIQRAFVAFDRRCDGFVTLDQLKRILTHFVFPMSDSLFEDLMRRCGIRASHK-IGYEQFLEKFQDPRVSGNGQTIPIKPNHKFNPVREAEDMPTTEDIWKF--LFSKVTDSFTSVKQAFLVFDDNKDGRITRRDFRRILES-FCFRMTEEQFHELMAKIDPMNRG-YISYLEFLDRFE 331
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Match: EDO46549 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ2]) HSP 1 Score: 69.707 bits (169), Expect = 2.541e-13 Identity = 62/217 (28.57%), Postives = 101/217 (46.54%), Query Frame = 1
Query: 148 TAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKP----KKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGG-DANLTRMPLFGNRSNIQSR-NSTTSR----HGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIF 768
A + AI+HPLS+M + + P R E K +P + SS + D+LN L NIPE I V D + +P+FG+R+++ SR S SR S++ K S++E +L+ K++ Y+ ++ F DP+ KG V +E+L +I+ VG I+ S N L + K+M++++E Y F
Sbjct: 2 AATTNLPAIQHPLSRMGNPANLNVRGTSRDGPRVASRQSLNLGESKLRPITADQMPWRLTKSSNGHNQRSPRDDLN-----LGNIPEGIEVRRAEDPSKPTIPIFGSRADMASRVESRMSRLSSAAASSRGPDKASVDEFEYLLREKMKTGYFTIKNLFKQRDPENKGIVSRESLSQILTTFVGKPISLSQFNKLMVRLNL-DHKKMIAYDEFYAAF 212
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Planmine SMEST
Match: SMESG000009107.1 (SMESG000009107.1) HSP 1 Score: 1731.84 bits (4484), Expect = 0.000e+0 Identity = 882/885 (99.66%), Postives = 884/885 (99.89%), Query Frame = 1
Query: 124 MSRPASVKTAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF 2778
MSRPASVKTAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKSMGSRSSSRVSRSDTSMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQ+KLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDS+LNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEA PVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENSSDKKKKLYSKKIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF
Sbjct: 1 MSRPASVKTAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKSMGSRSSSRVSRSDTSMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQSKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSDLNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEAVPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENSSDKKKKLYSKKIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF 885
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Planmine SMEST
Match: SMESG000009107.1 (SMESG000009107.1) HSP 1 Score: 1704.88 bits (4414), Expect = 0.000e+0 Identity = 869/872 (99.66%), Postives = 871/872 (99.89%), Query Frame = 1
Query: 163 MLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKXXXXXXXXXXXXXXXXMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSELNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF 2778
MLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKSMGSRSSSRVSRSDTSMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQ+KLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDS+LNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEA PVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENSSDKKKKLYSKKIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF
Sbjct: 1 MLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEDEQKYKPKKSMGSRSSSRVSRSDTSMDNLNLHGTFLTNIPESIAVVGGDANLTRMPLFGNRSNIQSRNSTTSRHGSAKEAVKLSLEEISEILQSKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCEITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIVPAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGIISYPIASLTPNVRASNDSFKLNLNASFIEKLLKTKLREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTDRDNKKSSNIDSDLNPVSLVEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNLPLNRNQTVPYLDFLKQFDTGNFSSLSFNDIHETSSVLNEAVPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEKKLLDFKEFTRHFMYNKSTASFPNAKLNPPVKGDSDLMQRSRKLNAATDILMDNLRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTPNNKIAYLELLKPFCSHKSQQILENSSDKKKKLYSKKIDQFNGKDSNSFHFFHKLQAVIQSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNSYDKNLNGSINYKMLLQDLQSKF 872
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Planmine SMEST
Match: SMESG000058629.1 (SMESG000058629.1) HSP 1 Score: 60.8474 bits (146), Expect = 5.317e-9 Identity = 115/610 (18.85%), Postives = 244/610 (40.00%), Query Frame = 1
Query: 1096 GIISYP---IASLTPNVRASNDSFKLNLNASFIEKLLKTK----------------LREGFTTLRQDFQKKDTNQTGFLSISDFIQVLSEHDLKLEESNLGEFLSRCIITPTKEGIPYKEFLIRFQDRSEAGITHKLLTD--RDNKKSSNIDSELNPVSL--VEFKLVNLFQKDFLEILENFRKFDKYQNGSIELKDFKKVLENQMNVEFTESQFKVIVDNL----PLNR------NQTVPYLDFLKQFD--TGNFSSLSFNDIHETSSVLNEADPVTDYNIEEIQSGKTVAEIKTIMKQAFDSKFGDIEKRFNELDEYNGKVLTPELMFQLMKTLDVKPELSRGDIRSVWKTFILNEK-KLLDFKEFTRHFMYN-------------KSTASFPNAKLNPPVK-----GDSDLMQRS-RKLNAA---TDILMDN---------LRAKIDLLYNDLLKEFTHLDPENNGAISVEDFQEIIKELSIHLTDHEIRIVTDKFKTP-NNKIAYLELLKPFCSHKSQQILENXXXXXXXXXXXXIDQFNGKDSNSFHFFHKLQAVI---QSAMIRNIKKIDSGNTGFISIAELRALLLLEGVSLSEDEVFNLMNS 2712
G +S+P I P +D ++ F++ L K + E F L F+ DT +GF+S+ +++LSE+ +E NL +FL++ G+ YK L Q + +K+++ + +S+ + S L +S+ +E ++ KDF+ K N E + +K++EN + T+ Q+K + PL+ N+ + + FL +F TG +D+ + N V ++ + A + ++ +F I+K++ LT ++F+L+ + K L+ ++ +W + L +++ +H M N +TA PN ++ K S L+ +K+ A D ++D+ + + ++ + K+ +D I + +E++ + LT E+ + F N + Y+E L F + + ++ + +++ G + +++ + ++IR +KID+ TG I ++L +LL G+ LS+D+++++ +
Sbjct: 322 GGVSFPLIRIPKWKPKGPGGSDEYEFGKGIQFVKGLQKLRDNRPEFSQIMDRLSYIFEEPFQALFTVFRHYDTKNSGFVSLDTGLKILSEYGFVIEIENLIKFLNKINCLDLNSGMNYKRMLTDIQTKGPGTCVNKVISQIIKAESQSTGLKS-LRTMSVDEIEQEVYKTLHKDFMSFQSQLEKASATSNLICE-NEARKIIENIIGHSMTKEQWKELQFQFDYCQPLSGKEEKDVNRLIDFRKFLNKFSKPTGICRYRFKSDLDKPIDWSNRNKKVKEF----YDPPRHHAYLCRMVADVLKFRFHAIDKQYKSFPIKEQGTLTKPILFELLNS--QKCSLTLQEMEIIWAVVESHPHYSSLHYRQVLKHLMMNLYKRAEEINIENRVTTAEDPNIEVLKEFKKTHKDDKSQLLDYCDKKIFMALLKKDFVVDSEKLQKTVEKMSPVLGSMWVPIKKQLRQIDVVGKATIEFYEMKELLIKNGFVLTPDEMENLLYAFDLKRNGRFYYIEFLHEFLKFRPDEGTAKPVLHFDRVRHQLLNEKTGGKLTVVKAYKEIRKTLLKQWKSLIRAFRKIDTDKTGKIDQSQLNQILLKSGIRLSKDDLYHVFSG 923 HSP 2 Score: 56.225 bits (134), Expect = 1.155e-7 Identity = 58/256 (22.66%), Postives = 110/256 (42.97%), Query Frame = 1
Query: 463 IQSRNSTTSRHGSAKEAVKLSLEEISEILQNKLEKNYYEVRKKFIDNDPDRKGNVQKEALMRIIQQIVGCE-ITTSCLNSLFEMWGIKSEKQMLSFNEIYTIFVNKSKEKSETSFFDPVNRHKAKAIV-----PAKMTATDAFDYIKEKFRSREMYLTDLFPDSVESQAFSITKADLKNSLYKIMIDLLPPEMEKLWLKFDQTKQGSIDSMKFLKQIGII--SYPIASLTPNVRASNDSFKLNLNASFIEKLLKTK 1206
I S+ T HG +++++EI I++ K + +++ F D + G V KEALM+I I C+ + L E + + +EK +++F+++ +F P ++ A I P ++A ++E ++ L L P+S + I A + +L K+ I L + +LW KFD GS+ + L + + P+ + P + L IE++++TK
Sbjct: 71 IFSKKITPRAHGD-----RMTVDEIDLIIREKFINERFSIQELFKVADEHKNGFVTKEALMKIFYTI--CDGLKVDHFYKLLERYKL-NEKPVIAFSDVEKVFG-----------LPPTGKYPAPQIFHGMGHPYNVSAGFGLQLLREAALDKDFDLKALLPESCFEEGGVILMAQFREALKKLKITLCAEDFIRLWRKFDIKGVGSVSQRQLLWILNLQDNGKPMCGIRPTF--------IPLKRPKIERVVRTK 299 The following BLAST results are available for this feature:
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 1
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of EF-hand calcium-binding domain-containing protein 6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001575 ID=SMED30001575|Name=EF-hand calcium-binding domain-containing protein 6|organism=Schmidtea mediterranea sexual|type=transcript|length=2902bpback to top protein sequence of SMED30001575-orf-1 >SMED30001575-orf-1 ID=SMED30001575-orf-1|Name=SMED30001575-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=886bp MSRPASVKTAVNKMLAIEHPLSKMAKENTFDNTVNNFLTPADEGRSLAFEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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