Methyltranfer_dom domain-containing protein

Overview
NameMethyltranfer_dom domain-containing protein
Smed IDSMED30001522
Length (bp)981
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Methyltranfer_dom domain-containing protein (SMED30001522) t-SNE clustered cells

Violin plots show distribution of expression levels for Methyltranfer_dom domain-containing protein (SMED30001522) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Methyltranfer_dom domain-containing protein (SMED30001522) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Methyltranfer_dom domain-containing protein (SMED30001522) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001522

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v4_3107_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v4_3107_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v4_3107_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v4_3107_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001522SMESG000073324.1 Contig48144newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001522SMESG000073324.1 Contig48144uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v6_3107_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30001522SMESG000073324.1 SMESG000056262.1 dd_Smed_v4_3107_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Human
Match: METTL24 (methyltransferase like 24 [Source:HGNC Symbol;Acc:HGNC:21566])

HSP 1 Score: 59.3066 bits (142), Expect = 3.076e-9
Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 3 
Query:  333 WDICIMPSF--AAKVSN--CLLYSFGI-NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWK-----IMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTA----EVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYD--SKRSKLPRTCCYEHYFVNTNF 923
            W +C+   F  A ++ N  C LYS G+ ++   F+ ++A    C V  FDPS+ +    +     +W++++ +   D   +   +       K+ S L  F  +   ID LK D+E +EW+  E++I + +L ++ QL+FE H      EV G  ++   F  +  +L +L +  F+ + H +    K     K+     + CY   +VNT +
Sbjct:  161 WSVCLDDRFNLAHQIRNKQCRLYSLGLGSDDTHFEVSMANN-GCEVHRFDPSVKSA--HILESQHLWYHRLSIDWRDPHPAVAAQKPHSNTRKLGSILNEFGHHK--IDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSDSSVVRF--WYSLLKELEQKDFRLF-HSYKDLSKPQLFLKKDIFNASSCYTLSWVNTRW 365
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Celegans
Match: Y40H7A.2 (pep chromosome:WBcel235:IV:15156655:15158984:1 gene:WBGene00012742.1 transcript:Y40H7A.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y40H7A.2)

HSP 1 Score: 51.2174 bits (121), Expect = 2.386e-7
Identity = 58/233 (24.89%), Postives = 96/233 (41.20%), Query Frame = 3 
Query:  222 LEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQ--KYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVN 914
            LE S   E+ ++Y +T+    F C   ++IG + D G   C  P  A   ++C + S G+N+  +FD+ I     Y+C +   D +  N   Q +         +G         +  K+ +M     M +   K ++ LKIDIE SE  A E  +++     V Q+L E H               + L +L K+ + GF+ +    N              T C E+ F+N
Sbjct:   12 LEMSKQNESHKFY-ETLRPEAF-CPLKLKIGGDGDSGKVTCD-PKRAR--NDCTMMSLGLNDQIQFDEEIQSITDYRCNIIGADMARQNATTQEKYAKMKGQLFVG------NVPDTLKLYRM-----MIDSESKEVEILKIDIESSEHAALEPFLKNYF---VCQILIEIHGLP-----------AKQLEMLRKISRLGFRMFNFERNPSC-----------TICCEYSFIN 203
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Celegans
Match: Y40H7A.3 (pep chromosome:WBcel235:IV:15161157:15164907:-1 gene:WBGene00012743.1 transcript:Y40H7A.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y40H7A.3)

HSP 1 Score: 50.447 bits (119), Expect = 5.723e-7
Identity = 59/234 (25.21%), Postives = 97/234 (41.45%), Query Frame = 3 
Query:  222 LEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQ--KYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPR-TCCYEHYFVN 914
            LE S   E+ ++Y +T+    F C   ++IG + D G   C  P  A   ++C + S G+N+  +FD+ I     Y+C +   D +  N   Q +         +G         +  K+ +M     M +   K ++ LKIDIE SE  A E  +++     V Q+L E H               + L +L K+ + GF+ +    N            P  T C E+ F+N
Sbjct:   66 LEMSKQNESHKFY-ETLRPEAF-CPLKLKIGGDGDSGKVTCD-PKRAR--NDCTMMSLGLNDQIQFDEEIQSITDYRCNIIGADMARQNATTQEKYAKMKGQLFVG------NVPDTLKLYRM-----MIDSESKEVEILKIDIESSEHAALEPFLKNYF---VCQILIEIHGLP-----------AKQLEMLRKISRLGFRMFNFERN------------PSCTICCEYSFIN 257
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Xenopus
Match: mettl24 (methyltransferase like 24 [Source:NCBI gene;Acc:100145735])

HSP 1 Score: 66.2402 bits (160), Expect = 1.372e-11
Identity = 57/215 (26.51%), Postives = 101/215 (46.98%), Query Frame = 3 
Query:  153 KLALQNSNSKSENEPTAESMALKL----EFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDG-----GWDICIMPSF--AAKVSN--CLLYSFGI----NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIM-----KMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETH 731
            K A   +N +  N+P    + L+       S D EA  +  + IT     C+  ++ G+ D        W +C+   F  A ++ N  C +YS G+    NN   F+  +A +  C V  FDPS+ +   Q+    ++W +++ +   D K +     +     K+ + L  F      ID LK D+E +EW+  E++I +G++ ++ QL+FE H
Sbjct:   80 KAANPATNRRDNNKPIRWHIDLQPWASSSHSLDSEAIRFL-RYITTTQIICSHRIKNGQTDQSVDASKPWTVCLDEKFNLAHQIRNKQCRVYSLGLGEDDNN---FEVNMASR-GCEVHRFDPSIAS--TQIHEGERLWHHRLSIDWRDPKPAIATHKLHITTKKLGTILNEF--GHWKIDVLKADMESAEWKILENLILEGVVEQIGQLIFEIH 285
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Mouse
Match: Mettl24 (methyltransferase like 24 [Source:MGI Symbol;Acc:MGI:3045338])

HSP 1 Score: 56.9954 bits (136), Expect = 1.092e-8
Identity = 56/216 (25.93%), Postives = 97/216 (44.91%), Query Frame = 3 
Query:  333 WDICIMPSFA----AKVSNCLLYSFGI-NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWK-----IMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTE-GFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDS--------KRSKLPRTCCYEHYFVNTNF 923
            W +C+   F      +   C LYS G+ ++   F+ ++A    C V  FDPS+ +    ++R   +W +++ +   D   +   +       K+ S L  F  +   ID LK D+E +EW+  E++I + +L ++ QL+FE H       V+ +E G VR+   L K  +      + HF  F  Y          K+     + CY   +VNT +
Sbjct:  158 WLVCLDDRFGLAHQIRSKRCRLYSLGLGSDDTHFEVSMANG-GCEVHRFDPSVKSA-HVLER-QGLWHHRLSIDWRDPHPAVAAQKPHGNTRKLGSILNEFGHHK--IDVLKADLESAEWKVLENLILEDVLEQIGQLVFEIHLHWPGFEVSGSESGVVRFWYSLLKELE------RKHFRLFHTYKDLTKPQLFLKKDLFNASSCYTLSWVNTKW 362
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. UniProt/SwissProt
Match: sp|B1WB06|MET24_XENTR (Methyltransferase-like protein 24 OS=Xenopus tropicalis OX=8364 GN=mettl24 PE=2 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 7.268e-11
Identity = 57/215 (26.51%), Postives = 101/215 (46.98%), Query Frame = 3 
Query:  153 KLALQNSNSKSENEPTAESMALKL----EFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDG-----GWDICIMPSF--AAKVSN--CLLYSFGI----NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIM-----KMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETH 731
            K A   +N +  N+P    + L+       S D EA  +  + IT     C+  ++ G+ D        W +C+   F  A ++ N  C +YS G+    NN   F+  +A +  C V  FDPS+ +   Q+    ++W +++ +   D K +     +     K+ + L  F      ID LK D+E +EW+  E++I +G++ ++ QL+FE H
Sbjct:   80 KAANPATNRRDNNKPIRWHIDLQPWASSSHSLDSEAIRFL-RYITTTQIICSHRIKNGQTDQSVDASKPWTVCLDEKFNLAHQIRNKQCRVYSLGLGEDDNN---FEVNMASR-GCEVHRFDPSIAS--TQIHEGERLWHHRLSIDWRDPKPAIATHKLHITTKKLGTILNEF--GHWKIDVLKADMESAEWKILENLILEGVVEQIGQLIFEIH 285
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5JXM2|MET24_HUMAN (Methyltransferase-like protein 24 OS=Homo sapiens OX=9606 GN=METTL24 PE=2 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 1.477e-8
Identity = 55/213 (25.82%), Postives = 101/213 (47.42%), Query Frame = 3 
Query:  333 WDICIMPSF--AAKVSN--CLLYSFGI-NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWK-----IMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTA----EVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYD--SKRSKLPRTCCYEHYFVNTNF 923
            W +C+   F  A ++ N  C LYS G+ ++   F+ ++A    C V  FDPS+ +    +     +W++++ +   D   +   +       K+ S L  F  +   ID LK D+E +EW+  E++I + +L ++ QL+FE H      EV G  ++   F  +  +L +L +  F+ + H +    K     K+     + CY   +VNT +
Sbjct:  161 WSVCLDDRFNLAHQIRNKQCRLYSLGLGSDDTHFEVSMANN-GCEVHRFDPSVKSA--HILESQHLWYHRLSIDWRDPHPAVAAQKPHSNTRKLGSILNEFGHHK--IDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSDSSVVRF--WYSLLKELEQKDFRLF-HSYKDLSKPQLFLKKDIFNASSCYTLSWVNTRW 365
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5BK01|MET24_RAT (Methyltransferase-like protein 24 OS=Rattus norvegicus OX=10116 GN=Mettl24 PE=2 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 3.346e-8
Identity = 55/216 (25.46%), Postives = 100/216 (46.30%), Query Frame = 3 
Query:  333 WDICIMPSFA----AKVSNCLLYSFGI-NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDT--------KWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTA----EVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYD--SKRSKLPRTCCYEHYFVNTNF 923
            W +C+   F      +   C LYS G+ ++   F+ ++A    C V  FDPS+ +    + +  ++W +++ +   D          +SN     K+ S L  F  +   ID LK D+E +EW+  E++I + +L ++ QL+FE H      EV G  ++   F  +  +L +L +  F+ + H +    K     K+     + CY   +VNT +
Sbjct:  158 WLVCLDDRFGLAHQIRTKQCRLYSLGLGSDDTHFEVSMANG-GCEVHRFDPSVRSA--HVLQSQRLWHHRLSIDWRDPHPAVAAQKPYSN---TRKLGSILNEFGHHK--IDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSESSVVRF--WYSLLKELERKDFRLF-HTYKDLSKPQLFLKKDIFNASSCYTLSWVNTRW 362
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8CCB5|MET24_MOUSE (Methyltransferase-like protein 24 OS=Mus musculus OX=10090 GN=Mettl24 PE=2 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 7.638e-8
Identity = 56/216 (25.93%), Postives = 97/216 (44.91%), Query Frame = 3 
Query:  333 WDICIMPSFA----AKVSNCLLYSFGI-NNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWK-----IMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTE-GFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDS--------KRSKLPRTCCYEHYFVNTNF 923
            W +C+   F      +   C LYS G+ ++   F+ ++A    C V  FDPS+ +    ++R   +W +++ +   D   +   +       K+ S L  F  +   ID LK D+E +EW+  E++I + +L ++ QL+FE H       V+ +E G VR+   L K  +      + HF  F  Y          K+     + CY   +VNT +
Sbjct:  158 WLVCLDDRFGLAHQIRSKRCRLYSLGLGSDDTHFEVSMANG-GCEVHRFDPSVKSA-HVLER-QGLWHHRLSIDWRDPHPAVAAQKPHGNTRKLGSILNEFGHHK--IDVLKADLESAEWKVLENLILEDVLEQIGQLVFEIHLHWPGFEVSGSESGVVRFWYSLLKELE------RKHFRLFHTYKDLTKPQLFLKKDLFNASSCYTLSWVNTKW 362
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Match: R7TGF9 (Methyltranfer_dom domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_227535 PE=4 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.885e-57
Identity = 95/223 (42.60%), Postives = 138/223 (61.88%), Query Frame = 3 
Query:  264 QTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQG--RVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            + +     +C    R+G   DGGWDIC    +A K   C++YSFGIN  + FDD+IA  + C VR+FDPSM N  D +    +V+FY++GLG  +T  + GW++  + S +K        ID +K+DIE++EW+ F +MI++G+L  VKQL+FE HT EV    R +T + F+R   +L  L + GF+++  H+N FG Y S RS   RTCCYE Y++N NFL
Sbjct:   55 KLVASTHMSCGELQRLGNLGDGGWDICSAEPYALK-PGCIVYSFGINFDFSFDDSIATNFGCEVRSFDPSM-NTGDHVH-SKQVYFYQLGLGPTNTVNTEGWRVQTLGSIMKKLHHLKTPIDVIKMDIEHNEWDCFRTMIKEGVLRNVKQLIFEMHTPEVYTVRRPSTKDDFIRMAAILRGLEEQGFRRYHFHYNSFGMYTSSRSGKSRTCCYELYYLNINFL 274
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BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Match: A0A267G515 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001919g1 PE=4 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 1.901e-53
Identity = 102/253 (40.32%), Postives = 144/253 (56.92%), Query Frame = 3 
Query:  177 SKSENEPTAESMA-LKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSN-CLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKED-TKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            SK+ N    ES+  + L   T+ + E+ Y+  + +    C  + R+G   DGGWD+C    F    S+ C+ +SFGINN+W+FDD +A+KY+C V  FDPSMT   D  QR    WFY+ GLG E+    S+GWK+  +   L      ++ ID +KIDIE+ EW + E  IQ+G L +VKQLLFE+HT E+   V  +  + R +RV   L+  GF+ WK H N        R+   R CCYEHY +NT  +
Sbjct:  360 SKTGNFNRLESLRRVNLSNQTERQVEDMYFAFVEQQQIACPFSRRVGDSGDGGWDVCFTAPFDISRSDPCVAFSFGINNIWKFDDQLAEKYRCKVYMFDPSMTGTSDH-QRKQTSWFYRTGLGAENKVDSSSGWKMRTLCHLLDELGYVNRPIDLVKIDIEHWEWSSLERAIQEGCLHQVKQLLFESHTGEM---VQVSTDYTRLVRVWLGLFNIGFRSWKWHKNPTSIIYRSRTGAERACCYEHYMLNTKLI 608

HSP 2 Score: 188.348 bits (477), Expect = 3.865e-51
Identity = 102/263 (38.78%), Postives = 148/263 (56.27%), Query Frame = 3 
Query:  138 DNGISKLALQNSNSKSENEPTAESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            DNGI +L     +++  + P    +A  L  S   E E  Y   + + T  C++  R+GR DDGGW++C+   F  K   C  +SFGINN+WEFDD +A+ ++C V TFDPSM    +   R  ++ F   GL        + W +     FL+ F+  D+VID LKIDIE+SEW A ++ ++DG L  VKQLL ETH      R  T   ++ Y  VL  L+  GF+ W +++N FG + S+     RTCC+E Y++N+NFL
Sbjct:   87 DNGIIRL----RSNRQRHYPRGNQLA-TLNVS---ELESLYENVLLELTAECSTNRRLGRTDDGGWNLCLTGPFGPK-QPCYSFSFGINNIWEFDDQVAKLFKCRVITFDPSMNK--ESFVRSERIVFLNEGLHAAKGTL-HSWPVDSYLGFLRRFKAEDRVIDILKIDIEHSEWPALKTAVKDGSLKNVKQLLLETHIK----REATANDYLEYFAVLESLHSLGFRLWHYNWNTFGNFISRHDATLRTCCHELYYINSNFL 333
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Match: A0A267FSJ7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001702g1 PE=4 SV=1)

HSP 1 Score: 193.741 bits (491), Expect = 4.316e-53
Identity = 102/253 (40.32%), Postives = 144/253 (56.92%), Query Frame = 3 
Query:  177 SKSENEPTAESMA-LKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSN-CLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKED-TKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            SK+ N    ES+  + L   T+ + E+ Y+  + +    C  + R+G   DGGWD+C    F    S+ C+ +SFGINN+W+FDD +A+KY+C V  FDPSMT   D  QR    WFY+ GLG E+    S+GWK+  +   L      ++ ID +KIDIE+ EW + E  IQ+G L +VKQLLFE+HT E+   V  +  + R +RV   L+  GF+ WK H N        R+   R CCYEHY +NT  +
Sbjct:  360 SKTGNFNRLESLRRVNLGNQTERQVEDMYFAFVEQQQIACPFSRRVGDSGDGGWDVCFTAPFDISRSDPCVAFSFGINNIWKFDDQLAEKYRCKVYMFDPSMTGTSDH-QRKQTSWFYRTGLGAENKVDSSSGWKMRTLCHLLDELGYVNRPIDIVKIDIEHWEWSSLERAIQEGCLHQVKQLLFESHTGEM---VQVSTDYTRLVRVWLGLFNIGFRSWKWHKNPTSIIYRSRTGAERACCYEHYMLNTKLI 608

HSP 2 Score: 187.963 bits (476), Expect = 5.437e-51
Identity = 102/263 (38.78%), Postives = 148/263 (56.27%), Query Frame = 3 
Query:  138 DNGISKLALQNSNSKSENEPTAESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            DNGI +L     +++  + P    +A  L  S   E E  Y   + + T  C++  R+GR DDGGW++C+   F  K   C  +SFGINN+WEFDD +A+ ++C V TFDPSM    +   R  ++ F   GL        + W +     FL+ F+  D+VID LKIDIE+SEW A ++ ++DG L  VKQLL ETH      R  T   ++ Y  VL  L+  GF+ W +++N FG + S+     RTCC+E Y++N+NFL
Sbjct:   87 DNGIIRL----RSNRQRHYPRGNQLA-TLNVS---ELESLYENVLLELTAECSTNRRLGRTDDGGWNLCLTGPFGPK-QPCYSFSFGINNIWEFDDQVAKLFKCRVITFDPSMNK--ESFVRSEQIVFLNEGLHAAKGTL-HSWPVDSYLGFLRRFKAEDRVIDILKIDIEHSEWPALKTAVKDGSLKNVKQLLLETHIK----RKATANDYLEYFAVLESLHSLGFRLWHYNWNTFGNFISRHDATLRTCCHELYYINSNFL 333
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Match: A0A267E6M5 (Methyltranfer_dom domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011725g1 PE=4 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 8.088e-53
Identity = 102/263 (38.78%), Postives = 148/263 (56.27%), Query Frame = 3 
Query:  138 DNGISKLALQNSNSKSENEPTAESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            DNGI +L     +++  + P    +A  L  S   E E  Y   + + T  C++  R+GR DDGGW++C+   F  K   C  +SFGINN+WEFDD +A+ ++C V TFDPSM    +   R  ++ F   GL        + W +     FL+ F+  D+VID LKIDIE+SEW A ++ ++DG L  VKQLL ETH      R  T   ++ Y  VL  L+  GF+ W +++N FG + S+     RTCC+E Y++N+NFL
Sbjct:   87 DNGIIRL----RSNRQRHYPRGNQLA-TLNVS---ELESLYENVLLELTAECSTNRRLGRTDDGGWNLCLTGPFGPK-QPCYSFSFGINNIWEFDDQVAKLFKCRVITFDPSMNK--ESFVRSEQIVFLNEGLHAAKGTL-HSWPVDSYLGFLRRFKAEDRVIDILKIDIEHSEWPALKTAVKDGSLKNVKQLLLETHIK----REATANDYLEYFAVLESLHSLGFRLWHYNWNTFGNFISRHDATLRTCCHELYYINSNFL 333
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Match: A0A267EB56 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031174g2 PE=4 SV=1)

HSP 1 Score: 187.193 bits (474), Expect = 1.068e-50
Identity = 103/255 (40.39%), Postives = 144/255 (56.47%), Query Frame = 3 
Query:  177 SKSENEPTAESMALKLEFS--TDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSN-CLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKY--DSKRSKLPRTCCYEHYFVNTNFL 926
            SK++N   A  + LK + +  T ++ E  Y+  + +    C  ++RIG   DGGWD+C    F  + S  C+ +SFGINN+W +DD +A KY C V  FDPSM N  D  QR +  WFY+ GL  E+    NGWK+  + +        +K ID LKIDIE+ EW +FE    +G L+ VKQLLFE+HT+E+   V     + R +RV   L+K GF+ WK H N    +   +   K  R CCYEHY +NTN +
Sbjct:  350 SKAKNFNKANDI-LKTDLTSLTSVQLEVMYFGILEQVHVNCPYSMRIGGTADGGWDVCFSRPFNIEESKPCIAFSFGINNIWSYDDILADKYHCNVHMFDPSM-NAKDH-QRKTTSWFYRTGLSSENKVEGNGWKMRTLCTLFSELGYRNKKIDILKIDIEHWEWTSFEKAFSEGCLTNVKQLLFESHTSEL---VRQKSDYGRLIRVWQGLFKLGFRTWKWHKNPQSLFFKSAASPKEQRACCYEHYMLNTNLV 598

HSP 2 Score: 167.162 bits (422), Expect = 3.217e-43
Identity = 93/238 (39.08%), Postives = 132/238 (55.46%), Query Frame = 3 
Query:  219 KLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGL-GKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSK-LPRTCCYEHYFVNTNFL 926
            KLE     E E+ Y   + + T  C++  R GR+ +GGW++C++  F      C  YSFG+NN+WEFDD +A  ++C V  FDP M+   +   R  KV F K G+  K+ T   NGW +      LK F   + +ID LK D+E  EW A E+ ++DG L  VKQLL ET   + +    T + F +Y  VL  LY +GF+QWKH++     Y S  +K L    C+E Y++N NFL
Sbjct:   98 KLESMNVAELEDLYESVVLETTADCSTERRFGRKGNGGWELCLVGPFTP-TKPCFSYSFGVNNIWEFDDEVAATFRCQVTAFDPRMSQ--ESHMRNDKVAFIKEGVYSKQGTL--NGWSVDSYLGHLKRFGAENFIIDILKFDVESLEWPALETAVRDGSLGNVKQLLLETRIEKTR----TKKNFKKYFSVLKSLYDTGFRQWKHNWKTNCNYRSSLNKDLDGKFCHELYYININFL 326
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Medaka
Match: mettl24 (methyltransferase like 24 [Source:NCBI gene;Acc:101164366])

HSP 1 Score: 72.0182 bits (175), Expect = 9.076e-14
Identity = 61/229 (26.64%), Postives = 108/229 (47.16%), Query Frame = 3 
Query:  231 STDIEAEEYY-YQTITKNTFTCNSAVRIG-REDDGGWDICIMPSFA----AKVSNCLLYSFGIN-NVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIM--------KMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTA----EVQGRVTTTEGFVRY-LRVLNKLYKSGFQQWKHHFNHFGKY 857
            S + EA+ +  Y T  + + T  S+ R   +     W +C+ P ++     K  +C +YSFG+  + W  +  +  +  C V  FDPS+  L    Q+ +++W +++ +   D    N   ++        K+++ L  F    + +D LK+D+E +EW+  E+++ +G+L  V QLL E H      EV G        VRY   +L +L  +GF  +  H N    Y
Sbjct:  113 SLEDEAKRFLSYITTPQVSCTSLSSKRTAWKGSSKSWAVCLDPKYSLIQKTKSKSCRVYSFGLGVSDWSLERFLG-RSGCQVHCFDPSLKQL---HQQEAEMWLHRLSVDWRDP---NPAAVVQNQHANSKKLATILNDF--GHRKVDVLKVDMESAEWKILENLVLEGVLDSVGQLLLEIHLHWAGFEVGG---DDPSVVRYWFSLLKELEDAGFHLFHTHTNPSKPY 329
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Match: SMESG000073324.1 (SMESG000073324.1)

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 275/279 (98.57%), Postives = 275/279 (98.57%), Query Frame = 3 
Query:   90 VLLLLCIGVYYRIMSVDNGISKLALQNSNSKSENEPTAESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            VLLLLCIGVYYRIMSVDNGISKLALQNSNSKSENEPTAESM LKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDD IAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEE DKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTE FVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL
Sbjct:   14 VLLLLCIGVYYRIMSVDNGISKLALQNSNSKSENEPTAESMGLKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDGIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEEKDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEEFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 292
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Match: SMESG000073324.1 (SMESG000073324.1)

HSP 1 Score: 550.436 bits (1417), Expect = 0.000e+0
Identity = 262/266 (98.50%), Postives = 262/266 (98.50%), Query Frame = 3 
Query:  129 MSVDNGISKLALQNSNSKSENEPTAESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            MSVDNGISKLALQNSNSKSENEPTAESM LKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDD IAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEE DKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTE FVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL
Sbjct:    1 MSVDNGISKLALQNSNSKSENEPTAESMGLKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDGIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEEKDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEEFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 266
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Match: SMESG000031406.1 (SMESG000031406.1)

HSP 1 Score: 377.867 bits (969), Expect = 3.468e-132
Identity = 170/261 (65.13%), Postives = 214/261 (81.99%), Query Frame = 3 
Query:  147 ISKLALQNSNSKSENEPTAE-SMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            I++  ++N  +K   +P+ + S+ L L F+T  +AEE+YY TITKN+FTCN ++RIGR DDGGWD+C + +F  K SNCL YSFG+NN+WEFDD +A+KY+CTVRTFDPSMT  PD+MQRPS VWFYKIGLGKEDT WSNGWKIMKMSS LK F E D++ID LKIDIE+SEW++FESMIQDGILSKVKQ+LFETHT E+QGR T+   +VR+L++ N LY +GF+QWK+H+NHFG+Y SK +   RTCC+EHY VNTN+L
Sbjct:   18 ITESKIRNKPTKYITKPSKKKSLELNLGFTTVTQAEEFYYATITKNSFTCNYSIRIGRPDDGGWDVCFVGNFNLKKSNCLSYSFGVNNIWEFDDEMAKKYECTVRTFDPSMTGYPDEMQRPSNVWFYKIGLGKEDTTWSNGWKIMKMSSLLKKFNEKDRIIDILKIDIEFSEWDSFESMIQDGILSKVKQILFETHTEELQGRTTSLASYVRFLKIWNTLYNAGFRQWKNHWNHFGQYSSKNTFKTRTCCFEHYLVNTNYL 278
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Match: SMESG000031406.1 (SMESG000031406.1)

HSP 1 Score: 379.022 bits (972), Expect = 3.819e-132
Identity = 170/261 (65.13%), Postives = 214/261 (81.99%), Query Frame = 3 
Query:  147 ISKLALQNSNSKSENEPTAE-SMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNKLYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL 926
            I++  ++N  +K   +P+ + S+ L L F+T  +AEE+YY TITKN+FTCN ++RIGR DDGGWD+C + +F  K SNCL YSFG+NN+WEFDD +A+KY+CTVRTFDPSMT  PD+MQRPS VWFYKIGLGKEDT WSNGWKIMKMSS LK F E D++ID LKIDIE+SEW++FESMIQDGILSKVKQ+LFETHT E+QGR T+   +VR+L++ N LY +GF+QWK+H+NHFG+Y SK +   RTCC+EHY VNTN+L
Sbjct:   48 ITESKIRNKPTKYITKPSKKKSLELNLGFTTVTQAEEFYYATITKNSFTCNYSIRIGRPDDGGWDVCFVGNFNLKKSNCLSYSFGVNNIWEFDDEMAKKYECTVRTFDPSMTGYPDEMQRPSNVWFYKIGLGKEDTTWSNGWKIMKMSSLLKKFNEKDRIIDILKIDIEFSEWDSFESMIQDGILSKVKQILFETHTEELQGRTTSLASYVRFLKIWNTLYNAGFRQWKNHWNHFGQYSSKNTFKTRTCCFEHYLVNTNYL 308
[Close]
BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Match: SMESG000012043.1 (SMESG000012043.1)

HSP 1 Score: 245.358 bits (625), Expect = 3.201e-81
Identity = 115/141 (81.56%), Postives = 122/141 (86.52%), Query Frame = 3 
Query:  300 AVRIGREDDGGWDICIMPSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQRPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIEYSEWEAFESMIQDGILSKVKQLLF 722
            AVRIGREDDG WD+CIMPSF  KVSN L YSFGINN+ +FDDA+AQKYQCTVRTFDPSMT+LPD MQ PSK W Y+IGLGKEDTKWSNGWKIMKMSSFL  FEE D VID LKIDIEYSEW AFESMI DGILS VKQ +F
Sbjct:   62 AVRIGREDDGDWDMCIMPSFGVKVSNYLTYSFGINNIMDFDDAVAQKYQCTVRTFDPSMTSLPDHMQCPSKGWIYRIGLGKEDTKWSNGWKIMKMSSFLNFFEEMDNVIDILKIDIEYSEWGAFESMIHDGILSNVKQFMF 202
The following BLAST results are available for this feature:
BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
METTL243.076e-925.82methyltransferase like 24 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y40H7A.22.386e-724.89pep chromosome:WBcel235:IV:15156655:15158984:1 gen... [more]
Y40H7A.35.723e-725.21pep chromosome:WBcel235:IV:15161157:15164907:-1 ge... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mettl241.372e-1126.51methyltransferase like 24 [Source:NCBI gene;Acc:10... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Mettl241.092e-825.93methyltransferase like 24 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|B1WB06|MET24_XENTR7.268e-1126.51Methyltransferase-like protein 24 OS=Xenopus tropi... [more]
sp|Q5JXM2|MET24_HUMAN1.477e-825.82Methyltransferase-like protein 24 OS=Homo sapiens ... [more]
sp|Q5BK01|MET24_RAT3.346e-825.46Methyltransferase-like protein 24 OS=Rattus norveg... [more]
sp|Q8CCB5|MET24_MOUSE7.638e-825.93Methyltransferase-like protein 24 OS=Mus musculus ... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R7TGF91.885e-5742.60Methyltranfer_dom domain-containing protein OS=Cap... [more]
A0A267G5151.901e-5340.32Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FSJ74.316e-5340.32Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267E6M58.088e-5338.78Methyltranfer_dom domain-containing protein OS=Mac... [more]
A0A267EB561.068e-5040.39Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Methyltranfer_dom domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mettl249.076e-1426.64methyltransferase like 24 [Source:NCBI gene;Acc:10... [more]
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BLAST of Methyltranfer_dom domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000073324.10.000e+098.57SMESG000073324.1[more]
SMESG000073324.10.000e+098.50SMESG000073324.1[more]
SMESG000031406.13.468e-13265.13SMESG000031406.1[more]
SMESG000031406.13.819e-13265.13SMESG000031406.1[more]
SMESG000012043.13.201e-8181.56SMESG000012043.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001522 ID=SMED30001522|Name=Methyltranfer_dom domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=981bp
ATATTGAAAACTGATTTTTCACAGTTAATTATTATTGAAAGTTATCAGTT
ATGAAGATTTCGAAAATATACACTTACATATCAATAATTGTTTTACTGTT
GCTTTGTATCGGAGTTTATTATCGGATTATGTCCGTTGATAATGGAATAT
CTAAATTGGCGTTACAAAATTCAAATTCAAAGTCAGAAAATGAACCGACT
GCAGAATCAATGGCATTAAAACTTGAATTTTCTACAGATATTGAAGCAGA
AGAATATTATTATCAAACAATAACCAAAAATACATTTACTTGCAATTCAG
CAGTCAGAATCGGTAGAGAGGATGATGGTGGTTGGGATATTTGTATTATG
CCAAGTTTTGCTGCGAAAGTTTCTAATTGTTTGTTGTATTCATTCGGAAT
TAATAATGTCTGGGAATTCGATGATGCAATTGCTCAGAAATATCAGTGCA
CAGTCAGGACATTTGATCCTTCAATGACAAATCTTCCCGATCAAATGCAG
CGTCCATCAAAAGTTTGGTTTTATAAAATTGGATTAGGTAAAGAAGACAC
CAAATGGTCAAATGGATGGAAAATTATGAAAATGTCATCATTCTTAAAAA
TGTTTGAAGAAAATGATAAAGTGATCGATTTTTTGAAAATCGATATTGAA
TATTCAGAATGGGAAGCTTTTGAATCCATGATCCAGGATGGGATTTTGTC
TAAAGTCAAACAGTTGTTGTTTGAAACTCACACAGCAGAAGTTCAAGGAC
GAGTGACAACGACGGAAGGGTTTGTGAGATATTTGCGGGTTTTAAACAAG
CTCTACAAATCCGGATTTCAACAATGGAAACATCATTTCAACCATTTCGG
AAAATACGATTCGAAGCGATCAAAATTACCTCGCACTTGTTGCTATGAAC
ATTATTTTGTAAATACCAATTTTCTTTGATATGTTCTATCTGTATTTTTT
AATAAAATTAATTTTGTTGTCTAAAAAAAAA
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protein sequence of SMED30001522-orf-1

>SMED30001522-orf-1 ID=SMED30001522-orf-1|Name=SMED30001522-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=293bp
MKISKIYTYISIIVLLLLCIGVYYRIMSVDNGISKLALQNSNSKSENEPT
AESMALKLEFSTDIEAEEYYYQTITKNTFTCNSAVRIGREDDGGWDICIM
PSFAAKVSNCLLYSFGINNVWEFDDAIAQKYQCTVRTFDPSMTNLPDQMQ
RPSKVWFYKIGLGKEDTKWSNGWKIMKMSSFLKMFEENDKVIDFLKIDIE
YSEWEAFESMIQDGILSKVKQLLFETHTAEVQGRVTTTEGFVRYLRVLNK
LYKSGFQQWKHHFNHFGKYDSKRSKLPRTCCYEHYFVNTNFL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0005576extracellular region
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0002056medial muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR026913METTL24
IPR025714Methyltranfer_dom
Vocabulary: molecular function
TermDefinition
GO:0008168methyltransferase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0032259methylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR025714Methyltransferase domainPFAMPF13383Methyltransf_22coord: 64..236
e-value: 7.1E-22
score: 78.2
NoneNo IPR availablePANTHERPTHR32026:SF10METHYLTRANSFERASE-LIKE PROTEIN 24coord: 36..291
NoneNo IPR availableTMHMMTMhelixcoord: 7..29
IPR026913Methyltransferase-like protein 24PANTHERPTHR32026FAMILY NOT NAMEDcoord: 36..291