Calcium-activated potassium channel slo-1, putative

Overview


Name	Calcium-activated potassium channel slo-1, putative
Smed ID	SMED30001493
Length (bp)	3071

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Calcium-activated potassium channel slo-1, putative (SMED30001493) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium-activated potassium channel slo-1, putative (SMED30001493) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium-activated potassium channel slo-1, putative (SMED30001493) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001493

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30001493	h1SMcG0019680	dd_Smed_v4_13498_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30001493	h1SMcG0019680	dd_Smed_v4_13498_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30001493	h1SMcG0019680	dd_Smed_v4_13498_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30001493	h1SMcG0019680	dd_Smed_v4_13498_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 447.973 bits (1151), Expect = 4.983e-142
Identity = 242/672 (36.01%), Postives = 386/672 (57.44%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK-----MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K      R+ K + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:   26 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 682

HSP 2 Score: 79.337 bits (194), Expect = 4.983e-142
Identity = 91/310 (29.35%), Postives = 150/310 (48.39%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  680 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 977

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 447.588 bits (1150), Expect = 5.369e-142
Identity = 241/668 (36.08%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  165 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 817

HSP 2 Score: 79.7221 bits (195), Expect = 5.369e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  815 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1114

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 447.588 bits (1150), Expect = 5.738e-142
Identity = 241/668 (36.08%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  209 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 861

HSP 2 Score: 79.337 bits (194), Expect = 5.738e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  859 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1158

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 447.588 bits (1150), Expect = 5.738e-142
Identity = 242/672 (36.01%), Postives = 386/672 (57.44%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK-----MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K      R+ K + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  165 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRSRKRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 821

HSP 2 Score: 79.337 bits (194), Expect = 5.738e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  819 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1118

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:HGNC Symbol;Acc:HGNC:6284])

HSP 1 Score: 447.588 bits (1150), Expect = 5.834e-142
Identity = 241/668 (36.08%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  165 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 817

HSP 2 Score: 79.337 bits (194), Expect = 5.834e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  815 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1114

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 469.544 bits (1207), Expect = 1.439e-151
Identity = 269/701 (38.37%), Postives = 405/701 (57.77%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSR---------------------QQFQYAVLDKAE----------------KEIDFLK-------------------CDYKDFKESLIKNPLEPIKFSN-HIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQ+ TG+ +V +  + +  ++  Y Y+A++   Q+E C I ++ +    IDL    FF  Y+ IRF+AA +K+ F   +YS +D  TIP  FV IYL   W+G RFLRA+ LM VPD+LQYL +LK+++  RL QL T+F+ + + G+G+ H+LEN+GD +    +N    +T+ DS+YF +VTMSTVGYGDI   +  G++++  FIL   A+FAS++PEIA+++ +  KY G Y  +   KHIVVCG+  + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F  GTVMD +DL R  I +ADAC +LAN    NP  EDAANIMRVIS+KN+SS +RV++QL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S  +  W+N Y+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+E+K    K   + INP        +T G+FI  S  E +R   +C  CH   +   L     KC C N +A      + ++   +R                     QQ Q  ++++                  + +DF K                   C  ++ ++ +++     +   N H+++C+FAD DSP IGL+NFI+PLRS    +  LK
Sbjct:  126 WAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETC-IPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGD-FFKGFINPHR-ITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSQTTPDWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCHDDIKDVSLIK---KCKCKN-LALFRRNTKHSTAARARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQRPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMKYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELK 813

HSP 2 Score: 88.1965 bits (217), Expect = 1.439e-151
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXX----------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQ 2989
            +L+ ++I  + E+L +EW++L   P +  ++ + +++  L  + +  C +CVI+SARV        D  L DKE IL +LN+K++                          +QKK       +P   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN     +I  L+ G      E+   E         +    +N  +C+I   +L D+ +     NT    Y  +FT A + Y  L +GLY++ +        S K+ ++TNP  E  +   D V  L+
Sbjct:  811 ELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTE----DTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVP---MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTT---YGAMFTIALRRYGQLCIGLYRLHDQDN---PDSMKRYVITNPPAELRIKNTDYVYVLE 1103

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 468.389 bits (1204), Expect = 3.563e-151
Identity = 267/701 (38.09%), Postives = 405/701 (57.77%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSR---------------------QQFQYAVLDKAE----------------KEIDFLK-------------------CDYKDFKESLIKNPLEPIKFSN-HIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQ+ TG+ +V +  + +  ++  Y Y+A++   Q+E C I ++ +    IDL    FF  Y+ IRF+AA +K+ F   +YS +D  TIP  FV IYL   W+G RFLRA+ LM VPD+LQYL +LK+++  RL QL T+F+ + + G+G+ H+LEN+GD +    +N    +T+ DS+YF +VTMSTVGYGDI   +  G++++  FIL   A+FAS++PEIA+++ +  KY G Y  +   KHIVVCG+  + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F  GTVMD +DL R  I +ADAC +LAN    NP  EDAANIMRVIS+KN+SS +RV++QL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S ++  W+NDY+ G G+E+YT +LS S   M+F +     +  L LLL+A+E+K    K   + INP        +T G+FI  S  E +R   +C  CH   +   L     KC C N +A      + ++   +R                     QQ Q  ++++                  + +DF K                   C  ++ ++ +++     +   N H+++C+FAD DSP IGL+NFI+PLRS    +  LK
Sbjct:  126 WAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETC-IPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGD-FFKGFINPHR-ITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPHTPLWLNDYLRGAGMEMYTESLSPSFANMSFPEAANLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCHDDIKDVSLIK---KCKCKN-LALFRRNTKHSTAARARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQRPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMKYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELK 813

HSP 2 Score: 88.1965 bits (217), Expect = 3.563e-151
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXX----------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQ 2989
            +L+ ++I  + E+L +EW++L   P +  ++ + +++  L  + +  C +CVI+SARV        D  L DKE IL +LN+K++                          +QKK       +P   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN     +I  L+ G      E+   E         +    +N  +C+I   +L D+ +     NT    Y  +FT A + Y  L +GLY++ +        S K+ ++TNP  E  +   D V  L+
Sbjct:  811 ELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTE----DTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVP---MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTT---YGAMFTIALRRYGQLCIGLYRLHDQDN---PDSMKRYVITNPPAELRIKNTDYVYVLE 1103

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 446.432 bits (1147), Expect = 7.613e-139
Identity = 245/577 (42.46%), Postives = 360/577 (62.39%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSR-----QQFQ 1956
            W  + ISGQ+ TG+ +V +  + +  ++  Y Y+A++   Q+E C I ++ +    IDL    FF  Y+ IRF+AA +K+ F   +YS +D  TIP  FV IYL   W+G RFLRA+ LM VPD+LQYL +LK+++  RL QL T+F+ + + G+G+ H+LEN+GD +    +N    +T+ DS+YF +VTMSTVGYGDI   +  G++++  FIL   A+FAS++PEIA+++ +  KY G Y  +   KHIVVCG+  + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F  GTVMD +DL R  I +ADAC +LAN    NP  EDAANIMRVIS+KN+SS +RV++QL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S  +  W+N Y+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+E+K    K   + INP        +T G+FI  S  E +R   +C  CH   +   L     KC C N +A      + ++   +R     QQFQ
Sbjct:  126 WAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETC-IPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGD-FFKGFINPHR-ITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSQTTPDWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCHDDIKDVSLIK---KCKCKN-LALFRRNTKHSTAARARATDVLQQFQ 689

HSP 2 Score: 88.1965 bits (217), Expect = 1.112e-26
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXX----------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQ 2989
            +L+ ++I  + E+L +EW++L   P +  ++ + +++  L  + +  C +CVI+SARV        D  L DKE IL +LN+K++                          +QKK       +P   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN     +I  L+ G      E+   E         +    +N  +C+I   +L D+ +     NT    Y  +FT A + Y  L +GLY++ +        S K+ ++TNP  E  +   D V  L+
Sbjct:  833 ELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTE----DTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVP---MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTT---YGAMFTIALRRYGQLCIGLYRLHDQDN---PDSMKRYVITNPPAELRIKNTDYVYVLE 1125

HSP 3 Score: 52.373 bits (124), Expect = 1.112e-26
Identity = 28/77 (36.36%), Postives = 43/77 (55.84%), Query Frame = 1

Query: 1945 QQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSN-HIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            QQFQ    D       F  C  ++ ++ +++     +   N H+++C+FAD DSP IGL+NFI+PLRS    +  LK
Sbjct:  762 QQFQDMKYDSTGM---FHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELK 835

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 445.662 bits (1145), Expect = 1.305e-138
Identity = 249/600 (41.50%), Postives = 368/600 (61.33%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKN 2040
            W  + ISGQ+ TG+ +V +  + +  ++  Y Y+A++   Q+E C I ++ +    IDL    FF  Y+ IRF+AA +K+ F   +YS +D  TIP  FV IYL   W+G RFLRA+ LM VPD+LQYL +LK+++  RL QL T+F+ + + G+G+ H+LEN+GD +    +N    +T+ DS+YF +VTMSTVGYGDI   +  G++++  FIL   A+FAS++PEIA+++ +  KY G Y  +   KHIVVCG+  + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F  GTVMD +DL R  I +ADAC +LAN    NP  EDAANIMRVIS+KN+SS +RV++QL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S  +  W+N Y+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+E+K    K   + INP        +T G+FI  S  E +R   +C  CH          D  K V      SL +K +  +  L R+  +++    A +E +    DY DF     +N
Sbjct:  126 WAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETC-IPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGD-FFKGFINPHR-ITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSQTTPDWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCH----------DDIKDV------SLIKKCKCKNLALFRRNTKHST---AAREKNAKISDYSDFDALFYQN 697

HSP 2 Score: 88.1965 bits (217), Expect = 1.280e-26
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXX----------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQ 2989
            +L+ ++I  + E+L +EW++L   P +  ++ + +++  L  + +  C +CVI+SARV        D  L DKE IL +LN+K++                          +QKK       +P   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN     +I  L+ G      E+   E         +    +N  +C+I   +L D+ +     NT    Y  +FT A + Y  L +GLY++ +        S K+ ++TNP  E  +   D V  L+
Sbjct:  831 ELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTE----DTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVP---MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTT---YGAMFTIALRRYGQLCIGLYRLHDQDN---PDSMKRYVITNPPAELRIKNTDYVYVLE 1123

HSP 3 Score: 52.373 bits (124), Expect = 1.280e-26
Identity = 28/77 (36.36%), Postives = 43/77 (55.84%), Query Frame = 1

Query: 1945 QQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSN-HIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            QQFQ    D       F  C  ++ ++ +++     +   N H+++C+FAD DSP IGL+NFI+PLRS    +  LK
Sbjct:  760 QQFQDMKYDSTGM---FHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELK 833

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Match: slo-1 (Calcium-activated potassium channel slo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q95V25])

HSP 1 Score: 445.662 bits (1145), Expect = 2.049e-138
Identity = 249/600 (41.50%), Postives = 368/600 (61.33%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKN 2040
            W  + ISGQ+ TG+ +V +  + +  ++  Y Y+A++   Q+E C I ++ +    IDL    FF  Y+ IRF+AA +K+ F   +YS +D  TIP  FV IYL   W+G RFLRA+ LM VPD+LQYL +LK+++  RL QL T+F+ + + G+G+ H+LEN+GD +    +N    +T+ DS+YF +VTMSTVGYGDI   +  G++++  FIL   A+FAS++PEIA+++ +  KY G Y  +   KHIVVCG+  + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F  GTVMD +DL R  I +ADAC +LAN    NP  EDAANIMRVIS+KN+SS +RV++QL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S  +  W+N Y+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+E+K    K   + INP        +T G+FI  S  E +R   +C  CH          D  K V      SL +K +  +  L R+  +++    A +E +    DY DF     +N
Sbjct:  126 WAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETC-IPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGD-FFKGFINPHR-ITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSQTTPDWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCH----------DDIKDV------SLIKKCKCKNLALFRRNTKHST---AAREKNAKISDYSDFDALFYQN 697

HSP 2 Score: 88.1965 bits (217), Expect = 1.159e-26
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXX----------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQ 2989
            +L+ ++I  + E+L +EW++L   P +  ++ + +++  L  + +  C +CVI+SARV        D  L DKE IL +LN+K++                          +QKK       +P   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN     +I  L+ G      E+   E         +    +N  +C+I   +L D+ +     NT    Y  +FT A + Y  L +GLY++ +        S K+ ++TNP  E  +   D V  L+
Sbjct:  853 ELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTE----DTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVP---MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTT---YGAMFTIALRRYGQLCIGLYRLHDQDN---PDSMKRYVITNPPAELRIKNTDYVYVLE 1145

HSP 3 Score: 52.373 bits (124), Expect = 1.159e-26
Identity = 28/77 (36.36%), Postives = 43/77 (55.84%), Query Frame = 1

Query: 1945 QQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSN-HIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            QQFQ    D       F  C  ++ ++ +++     +   N H+++C+FAD DSP IGL+NFI+PLRS    +  LK
Sbjct:  782 QQFQDMKYDSTGM---FHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELK 855

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0301582)

HSP 1 Score: 475.322 bits (1222), Expect = 6.790e-149
Identity = 244/562 (43.42%), Postives = 355/562 (63.17%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH-GANEGTPLRVDKFKCVCINKVASLNEKIR 1920
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS+IPEI E+    SKY G+Y      +HIVVCG+  + S+  F+ DF +EDR    + VVF++++EPD EL  LLK ++    F +GT+M+ VDL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  SW NDY+ G G+E+YT  LS + IG+ F       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH    + T ++    KC C N +A+  + +R
Sbjct:   97 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDASS--EEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAVFASWIPEITELAAQRSKYGGTYSKDPRKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKEPDLELEGLLKRHYTTVAFFQGTMMNAVDLERVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIK----KCKCKN-LATFRKGVR 640

HSP 2 Score: 92.8189 bits (229), Expect = 2.164e-26
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  874 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1169

HSP 3 Score: 46.9802 bits (110), Expect = 2.164e-26
Identity = 17/38 (44.74%), Postives = 27/38 (71.05%), Query Frame = 1

Query: 2059 FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
             + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  839 LNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 876

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0330286)

HSP 1 Score: 473.396 bits (1217), Expect = 3.312e-148
Identity = 244/555 (43.96%), Postives = 349/555 (62.88%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH-GANEGTPLRVDKFKCVCINKVA 1899
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS+IPEI E+    SKY G+Y      +HIVVCG+  + S+  F+ DF +EDR    + VVF++++EPD EL  LLK ++    F +GT+M+ VDL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  +W NDY+ G G E+YT  LS S  GMTF       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH    + T ++    KC C N V 
Sbjct:   97 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDASS--EEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAVFASWIPEITELAAQRSKYGGTYSKDPRKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKEPDLELEGLLKRHYTTVAFFQGTMMNAVDLERVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIK----KCKCKNYVG 634

HSP 2 Score: 92.8189 bits (229), Expect = 2.128e-26
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  881 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1176

HSP 3 Score: 47.3654 bits (111), Expect = 2.128e-26
Identity = 17/38 (44.74%), Postives = 27/38 (71.05%), Query Frame = 1

Query: 2059 FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
             + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  846 LNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 883

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0100622)

HSP 1 Score: 472.241 bits (1214), Expect = 3.626e-148
Identity = 235/532 (44.17%), Postives = 340/532 (63.91%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH 1833
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS+IPEI E+    SKY G+Y      +HIVVCG+  + S+  F+ DF +EDR    + VVF++++ PD EL  L K +F   +F +GT+M+ +DL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  SW NDY+ G G+E+YT  LS + IG+ F       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH
Sbjct:  114 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDAS--SEEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAVFASWIPEITELAAQRSKYGGTYSKDPRKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACH 632

HSP 2 Score: 93.2041 bits (230), Expect = 1.882e-26
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  839 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1134

HSP 3 Score: 46.9802 bits (110), Expect = 1.882e-26
Identity = 19/48 (39.58%), Postives = 30/48 (62.50%), Query Frame = 1

Query: 2029 LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            L +N       + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  794 LDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 841

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0100624)

HSP 1 Score: 471.47 bits (1212), Expect = 7.925e-148
Identity = 237/532 (44.55%), Postives = 342/532 (64.29%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH 1833
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS IPEI E++ SG+KY G    +   +HIVVCG+  + S+  F+ DF +EDR    + VVF++++EPD EL  LLK ++    F +GT+M+ VDL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  SW NDY+ G G+E+YT  LS + IG+ F       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH
Sbjct:  114 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDAS--SEEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKEPDLELEGLLKRHYTTVAFFQGTMMNAVDLERVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACH 632

HSP 2 Score: 93.2041 bits (230), Expect = 1.776e-26
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  839 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1134

HSP 3 Score: 47.3654 bits (111), Expect = 1.776e-26
Identity = 19/48 (39.58%), Postives = 30/48 (62.50%), Query Frame = 1

Query: 2029 LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            L +N       + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  794 LDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 841

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Match: slo (gene:FBgn0003429 transcript:FBtr0334294)

HSP 1 Score: 469.544 bits (1207), Expect = 1.855e-147
Identity = 244/563 (43.34%), Postives = 353/563 (62.70%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH-GANEGTPLRVDKFKCVCINKVASLNEKIRQ 1923
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS IPEI E++ SG+KY G    +   +HIVVCG+  + S+  F+ DF +EDR    + VVF++++ PD EL  L K +F   +F +GT+M+ +DL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  +W NDY+ G G E+YT  LS S  GMTF       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH    + T ++    KC C N    LN  +R+
Sbjct:   97 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDAS--SEEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDTQAWQNDYLQGTGCEMYTETLSPSFTGMTFPQASELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACHEDIKDETLIK----KCKCKNL---LNRNVRR 639

HSP 2 Score: 93.2041 bits (230), Expect = 1.734e-26
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  799 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1094

HSP 3 Score: 47.3654 bits (111), Expect = 1.734e-26
Identity = 19/48 (39.58%), Postives = 30/48 (62.50%), Query Frame = 1

Query: 2029 LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            L +N       + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  754 LDRNQAAMTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 801

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 447.588 bits (1150), Expect = 1.367e-143
Identity = 243/669 (36.32%), Postives = 383/669 (57.25%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK-----MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQT----------SFRLSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K      R+ K + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  I     ++L+ K +Q           S ++ R          Q   +D   K  D    F  C  K+ ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  136 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESRSRKRILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRIEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 792

HSP 2 Score: 84.3445 bits (207), Expect = 1.367e-143
Identity = 90/315 (28.57%), Postives = 154/315 (48.89%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D +  L
Sbjct:  790 ELKPIVFVGSLDYLRREWETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCL 1092

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 446.047 bits (1146), Expect = 3.932e-143
Identity = 241/665 (36.24%), Postives = 382/665 (57.44%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQT----------SFRLSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K    + ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  I     ++L+ K +Q           S ++ R          Q   +D   K  D    F  C  K+ ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  119 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESSILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRIEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 771

HSP 2 Score: 84.3445 bits (207), Expect = 3.932e-143
Identity = 90/315 (28.57%), Postives = 154/315 (48.89%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D +  L
Sbjct:  769 ELKPIVFVGSLDYLRREWETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCL 1071

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 446.817 bits (1148), Expect = 6.499e-138
Identity = 241/665 (36.24%), Postives = 382/665 (57.44%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQT----------SFRLSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K    + ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  I     ++L+ K +Q           S ++ R          Q   +D   K  D    F  C  K+ ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  136 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVYARTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSYIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESSILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRIEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMRHDPLLIPGNEQIESMDANVKRYDSTGMFHWCPSKEIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 788

HSP 2 Score: 59.6918 bits (143), Expect = 1.923e-8
Identity = 58/179 (32.40%), Postives = 98/179 (54.75%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D +  L
Sbjct:  942 MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEMVPTDLIFCL 1116

HSP 3 Score: 51.2174 bits (121), Expect = 7.562e-6
Identity = 28/83 (33.73%), Postives = 47/83 (56.63%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNV 2410
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+
Sbjct:  786 ELKPIVFVGSLDYLRREWETLHNFPKVFILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNI 863

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Match: CABZ01092907.1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1b [Source:NCBI gene;Acc:798583])

HSP 1 Score: 378.637 bits (971), Expect = 7.762e-121
Identity = 184/462 (39.83%), Postives = 292/462 (63.20%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTF 1638
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +++  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F
Sbjct:    7 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIESCE-HFDKNFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSYIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSF 457

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Match: si:dkey-21e5.1 (si:dkey-21e5.1 [Source:ZFIN;Acc:ZDB-GENE-141210-6])

HSP 1 Score: 132.494 bits (332), Expect = 7.208e-31
Identity = 93/341 (27.27%), Postives = 167/341 (48.97%), Query Frame = 1

Query:  787 LTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPK--EEYKHIVVC-GNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNF--MRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLI-----GMTFYDLVLFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFI 1779
            LT  D++YF IVT STVGYGD++P  +  ++ V I I V+  +      E+A +     K  G+Y     +  KH+V+C  + +   +  F+ +F+   R +    VV +   E D ++R +L++     R  +++G+ +   DL RA +D+A+ACFIL++ N  +    D   I+R  ++K+F+ +  + +Q+L+ ENK ++           D VVC  E +  +LA +C+ P  ST ++ L      ++ +E + S   W   Y    G E+Y   L  S       G +F      +++   + LI    K  + K++ +NP  +   +     Y+I
Sbjct:  178 LTLFDALYFCIVTFSTVGYGDVTPRIWPSQLLVVIMICVALVVLPLQFEELAYLWMERQKSGGNYSRHRAQTEKHVVLCVTSLKIDLLMDFLNEFYAHPR-LQDYYVVILCPTEMDIQVRRILQIPLWSQRVIYLQGSALKDQDLMRAKMDDAEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKF--------ADHVVCEEEFKYAMLALNCVCPATSTLVTLLVHT---SRGQEGQTSPEQWQRTYGRCSGNEVYHIRLMDSKFFGEYDGKSFTYASFHAHKKYGVCLIG--TKREDNKSILLNPGPRHIMSATDTCYYI 504

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 444.506 bits (1142), Expect = 6.907e-141
Identity = 238/666 (35.74%), Postives = 378/666 (56.76%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN---------KVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEID---------------FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V      +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + E  +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K   G++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +          K    N  +RQ+            +L     +ID               F  C  K+  + L+      +   S H+++CIF D  S  IG++N ++PLR+    +  LK
Sbjct:  116 WAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSN---PIETCQNFYKD-FTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFE--NSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPGNHVKIKEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELK 769

HSP 2 Score: 79.337 bits (194), Expect = 6.907e-141
Identity = 88/310 (28.39%), Postives = 151/310 (48.71%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                   ++  I     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +L+  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  767 ELKHIVFVGSLDYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 1064

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 441.81 bits (1135), Expect = 3.833e-140
Identity = 235/666 (35.29%), Postives = 377/666 (56.61%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN---------KVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEID---------------FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V      +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + E  +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FA ++PEIA ++ +  KY G++      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K   G++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +          K    N  +RQ+            +L     +ID               F  C  K+  + L+      +   S H+++CIF D  S  IG++N ++PLR+    +  LK
Sbjct:  162 WAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSN---PIETCQNFYKD-FTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFE--NSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGTFNATRGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPGNHVKIKEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELK 815

HSP 2 Score: 78.9518 bits (193), Expect = 3.833e-140
Identity = 89/315 (28.25%), Postives = 153/315 (48.57%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ I+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                   ++  I     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +L+  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +  L
Sbjct:  813 ELKHIVFVGSLDYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCL 1115

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 437.187 bits (1123), Expect = 1.042e-138
Identity = 238/684 (34.80%), Postives = 377/684 (55.12%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC---------------------------VCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEID---------------FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V      +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + E  +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K   G++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C                               K    N  +RQ+            +L     +ID               F  C  K+  + L+      +   S H+++CIF D  S  IG++N ++PLR+    +  LK
Sbjct:  162 WAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSN---PIETCQNFYKD-FTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFE--NSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPGNHVKIKEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCACKRRSQFHKSPLQNKKKGNGPFEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELK 833

HSP 2 Score: 79.337 bits (194), Expect = 1.042e-138
Identity = 88/310 (28.39%), Postives = 151/310 (48.71%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                   ++  I     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +L+  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  831 ELKHIVFVGSLDYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 1128

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 435.647 bits (1119), Expect = 2.923e-138
Identity = 238/690 (34.49%), Postives = 378/690 (54.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-------------------------VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN---------KVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEID---------------FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V      +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + E  +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K   G++                         + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +          K    N  +RQ+            +L     +ID               F  C  K+  + L+      +   S H+++CIF D  S  IG++N ++PLR+    +  LK
Sbjct:   99 WAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSN---PIETCQNFYKD-FTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFE--NSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRGSKLEAVDILARFCVITFRVFFTRIIINPGNHVKIKEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELK 776

HSP 2 Score: 79.337 bits (194), Expect = 2.923e-138
Identity = 89/315 (28.25%), Postives = 153/315 (48.57%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ I+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                   ++  I     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +L+  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +  L
Sbjct:  774 ELKHIVFVGSLDYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPVHGVARQASITTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCL 1076

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Match: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:100491898])

HSP 1 Score: 444.891 bits (1143), Expect = 5.054e-138
Identity = 238/666 (35.74%), Postives = 378/666 (56.76%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN---------KVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEID---------------FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V      +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + E  +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K   G++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +          K    N  +RQ+            +L     +ID               F  C  K+  + L+      +   S H+++CIF D  S  IG++N ++PLR+    +  LK
Sbjct:   27 WAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSN---PIETCQNFYKD-FTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFE--NSQDLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEFKSEKGESRIIINPGNHVKIKEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRQSPNSSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELK 680

HSP 2 Score: 58.5362 bits (140), Expect = 6.861e-8
Identity = 56/174 (32.18%), Postives = 97/174 (55.75%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +L+  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  834 IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLYCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 1003

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 447.588 bits (1150), Expect = 3.610e-142
Identity = 241/668 (36.08%), Postives = 385/668 (57.63%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   +  +L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  100 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 752

HSP 2 Score: 79.7221 bits (195), Expect = 3.610e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  750 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1049

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 447.588 bits (1150), Expect = 3.890e-142
Identity = 241/668 (36.08%), Postives = 385/668 (57.63%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   +  +L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  100 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 752

HSP 2 Score: 79.337 bits (194), Expect = 3.890e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  750 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1049

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 447.203 bits (1149), Expect = 4.829e-142
Identity = 241/668 (36.08%), Postives = 385/668 (57.63%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   +  +L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  165 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 817

HSP 2 Score: 79.337 bits (194), Expect = 4.829e-142
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  815 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1114

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 447.203 bits (1149), Expect = 4.993e-142
Identity = 241/668 (36.08%), Postives = 385/668 (57.63%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   +  +L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  100 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DVTDPKRIKKCGCRRLEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 752

HSP 2 Score: 79.7221 bits (195), Expect = 4.993e-142
Identity = 92/315 (29.21%), Postives = 152/315 (48.25%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +  L
Sbjct:  750 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCL 1052

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Match: Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923])

HSP 1 Score: 447.203 bits (1149), Expect = 7.023e-142
Identity = 242/671 (36.07%), Postives = 385/671 (57.38%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC-----VCINKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C     V   +  +L+ K +Q          TS +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:   40 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DVTDPKRIKKCGCRRPVYVEDEQPPTLSPKKKQRNGGMRNSPNTSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 695

HSP 2 Score: 79.337 bits (194), Expect = 7.023e-142
Identity = 91/310 (29.35%), Postives = 150/310 (48.39%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  693 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 990

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Match: sp|Q03720|SLO_DROME (Calcium-activated potassium channel slowpoke OS=Drosophila melanogaster OX=7227 GN=slo PE=1 SV=3)

HSP 1 Score: 469.544 bits (1207), Expect = 6.346e-146
Identity = 235/532 (44.17%), Postives = 341/532 (64.10%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN---GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH 1833
            W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++ERC   +       IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  FV IYLD  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++FI +W+  +G+ H+LEN+GD     + N+ + L++   +YF IVTMSTVGYGD+   + LG+ ++  F+LV  A+FAS IPEI E++ SG+KY G    +   +HIVVCG+  + S+  F+ DF +EDR    + VVF++++ PD EL  L K +F   +F +GT+M+ +DL+R  + EADAC +LAN  C++P  EDAANIMRVIS+KN+S  +RV+IQL+QY NK+YL NIP+W+  +GD V+C +E++L  +A+SCL PG+ST ++NLF++RS      F+ S +  SW NDY+ G G+E+YT  LS + IG+ F       +  L LLL+A+E+K         + INP   +     T G+FI  S  E +R   YC  CH
Sbjct:  114 WAGELISGQTTTGRILVVLVFILSIASLIIYFVDASS--EEVERCQ-KWSNNITQQIDLAFNIFFMVYFFIRFIAASDKLWFMLEMYSFVDYFTIPPSFVSIYLDRTWIGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFISVWLTAAGIIHLLENSGDPL---DFNNAHRLSYWTCVYFLIVTMSTVGYGDVYCETVLGRTFLVFFLLVGLAMFASSIPEIIELVGSGNKYGGELKREHGKRHIVVCGHITYESVSHFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTIMNPIDLQRVKVHEADACLVLANKYCQDPDAEDAANIMRVISIKNYSDDIRVIIQLMQYHNKAYLLNIPSWDWKQGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRS------FKTSPDMQSWTNDYLRGTGMEMYTETLSPTFIGIPFAQATELCFSKLKLLLLAIEIKGAEEGADSKISINPRG-AKIQANTQGFFIAQSADEVKRAWFYCKACH 632

HSP 2 Score: 93.2041 bits (230), Expect = 1.678e-25
Identity = 90/304 (29.61%), Postives = 154/304 (50.66%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEI---------------------PNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  + +++ REW+ L   P +  ++ + +++  L  + V  C +C I+SA+V     +N D  L DKE IL +LN+K++           +  E                       N  +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    +N  +C++   +L+D      F    +  Y +LF  A K Y +L +GLY+  +T+ +  +SSK+ VI TNP  +FS+   D V  L
Sbjct:  864 ELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCCILSAKV----PSNDDPTLADKEAILASLNIKAMTFDDTIGVLSQRGPEFDNLSATAGSPIVLQRRGSVYGANVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTVESLSNRDRCRVGQISLYDGPLAQ-FGECGK--YGDLFVAALKSYGMLCIGLYRFRDTSSSCDASSKRYVI-TNPPDDFSLLPTDQVFVL 1159

HSP 3 Score: 46.9802 bits (110), Expect = 1.678e-25
Identity = 17/38 (44.74%), Postives = 27/38 (71.05%), Query Frame = 1

Query: 2059 FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
             + H+++C+FAD DSP IGL+N ++PLR+    +  LK
Sbjct:  829 LNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELK 866

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Match: sp|Q8AYS8|KCMA1_CHICK (Calcium-activated potassium channel subunit alpha-1 OS=Gallus gallus OX=9031 GN=KCNMA1 PE=1 SV=2)

HSP 1 Score: 452.595 bits (1163), Expect = 2.612e-143
Identity = 244/665 (36.69%), Postives = 389/665 (58.50%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N +  LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL PG ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  +   ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          +S +L R          Q   +D   K+ D    F  C  KD ++  L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  124 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWENFQNNQQ--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAPGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELVFAKLKLLMIAIEYKSEKRESSILINPGNHVKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHDPLLIPGNEQIDNMDANVKKYDSTGMFHWCPAKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSALIGLRNLVMPLRASNFHYHELK 776

HSP 2 Score: 81.2629 bits (199), Expect = 2.612e-143
Identity = 91/310 (29.35%), Postives = 152/310 (49.03%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  774 ELKHIVFVGSLEYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLLRQPSITTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 1071

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Match: sp|Q9BG98|KCMA1_RABIT (Calcium-activated potassium channel subunit alpha-1 OS=Oryctolagus cuniculus OX=9986 GN=KCNMA1 PE=2 SV=1)

HSP 1 Score: 446.432 bits (1147), Expect = 5.230e-141
Identity = 240/668 (35.93%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          +S +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  166 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 818

HSP 2 Score: 79.7221 bits (195), Expect = 5.230e-141
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  816 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1115

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Match: sp|Q28204|KCMA1_BOVIN (Calcium-activated potassium channel subunit alpha-1 OS=Bos taurus OX=9913 GN=KCNMA1 PE=1 SV=2)

HSP 1 Score: 446.432 bits (1147), Expect = 5.452e-141
Identity = 240/668 (35.93%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          +S +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  153 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPSSSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 805

HSP 2 Score: 79.337 bits (194), Expect = 5.452e-141
Identity = 91/312 (29.17%), Postives = 151/312 (48.40%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSV 2977
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D +
Sbjct:  803 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLI 1102

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Match: sp|O18866|KCMA1_PIG (Calcium-activated potassium channel subunit alpha-1 (Fragment) OS=Sus scrofa OX=9823 GN=KCNMA1 PE=2 SV=2)

HSP 1 Score: 446.432 bits (1147), Expect = 5.876e-141
Identity = 240/668 (35.93%), Postives = 386/668 (57.78%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKT-VFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKES---------------LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W + + N    LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LL+IA+E K  N ++ + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +   + ++L+ K +Q          +S +L R      +L     +ID +  + K +  +               L ++       S H+++CIF D  S  IGL+N ++PLR+    +  LK
Sbjct:  139 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSN---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQA--LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPSSSPKLMRHD---PLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELK 791

HSP 2 Score: 79.337 bits (194), Expect = 5.876e-141
Identity = 91/310 (29.35%), Postives = 150/310 (48.39%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  L++  I     IP   +IT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  789 ELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIP---IITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRD-RCRVAQLALLDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTD 1086

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BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Match: A0A023VZW9 (SLO-1 2 OS=Trichuris muris OX=70415 PE=2 SV=1)

HSP 1 Score: 491.115 bits (1263), Expect = 1.536e-161
Identity = 276/686 (40.23%), Postives = 404/686 (58.89%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN----------------KVASLNEKIRQTS----------------FRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFS----------NHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQ+TTG+I+V +  + +  ++  Y Y+A++   Q+E C I +  +    IDL    FF  Y+ IRF+AA +K+ F   VYS VD  TIP  FV IYL+  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++F+ + + G+G  H+LEN+GD +      +   +T+ + +YF +VTM TVGYGDI   + LG++++  FIL   A+FAS+IPEIA+++ S  KY G Y  +   KHIVVCG   + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F +GTVMD +DL R  + +ADAC ILAN    +P  EDAANIMRVISLKN+S  +RV++QL+QY NK+YL NIP+WN   GD V+C +E++L ILA+SCL PG+ST ++NLF++RS      F+ S N+  W+NDY+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+EVK  +    T+ INP S +     T G+FI  S  E +R   YC  CH   +   + + K KC  +                 KV S  E+I +                   R  R   + ++ +  + + + +K D           P+E +             NH+++C+FAD +SP IGL++F++PLR+    +  LK
Sbjct:  144 WAGELISGQSTTGRILVVLVFILSIGSLIIYFYDASHPNFQVETC-ISWSKSPSQQIDLAFNIFFLIYFFIRFVAATDKVWFLLEVYSFVDYFTIPPSFVAIYLERTWLGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFVSVSLTGAGFLHLLENSGDPF--QNFQNPQRITYWECVYFLVVTMGTVGYGDICCKTSLGRLFMVFFILGGLAMFASYIPEIADLIGSRQKYGGEYKSENGKKHIVVCGYITYESVSHFLQDFLHEDRDDVDVEVVFVHRVPPDLELEGLFKRHFTKVEFFQGTVMDSIDLSRVKVHKADACLILANKYSSDPDAEDAANIMRVISLKNYSPDIRVIVQLMQYHNKAYLLNIPSWNWKTGDDVICLAELKLGILAQSCLAPGFSTMMANLFAMRS------FKTSPNTPCWLNDYLRGAGMEIYTETLSHSFVGMTFPETVELIFVKLKLLLLAIEVKDDDNLECTIIINPESSAVIKVNTQGFFIAQSADEVKRAFYYCQKCHEDIQDVNM-IKKCKCRNLTLFRKGVRHIILANRTAKVLSPPERITKDDTGEIEGDNRYLADAIMTRDLRIPARASLTNGDKTDENDMKYDSTGMFHWCRARPIEEVILQREQAATTLLRNHVVICMFADKNSPLIGLRSFVMPLRASNYHYHELK 819

HSP 2 Score: 110.923 bits (276), Expect = 1.536e-161
Identity = 90/305 (29.51%), Postives = 151/305 (49.51%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXX--------------------XXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFE--NINDEEST-NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQP 2992
            +L+ ++I  + E+L REW+ L   P +  ++ N +++  L  + V  C +CVI+SAR+   N    D  L DKE IL +LN+K++                             I    +IP   L+T+L+ ++NVQFLDQ+DED+PN  ++L++ F CG AF   +LD L+S  YFN     +I   + G      E+   E  ++    ST  +     +C+I  + + +  F + F     C Y +LF  A + + +LL+GLY++ E   + L+   K+ ++T P     +   D V  L+P
Sbjct:  817 ELKHVVIVGDVEYLRREWKMLQNMPKITVLNGNPLSRADLRAVNVNLCDMCVIISARIPNPNE---DPTLTDKEAILASLNIKAMNFDATTALLYHPLGNHGLNSPPMALCESRIKSGTQIP---LLTELVNDSNVQFLDQDDEDDPNTELYLTQPFTCGKAFAISVLDSLMSTTYFNDSALTLIRTFVTGGATPELEVILAEGGDLKGAPSTPQLLRKRDRCRIAQYGITEGPFVN-FGVQEGCTYGSLFLQALRRHGMLLIGLYRLQEAQPDELT---KRFVITAPPENMRLQITDLVFVLEP 1111

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Match: A0A085MB25 (Uncharacterized protein OS=Trichuris suis OX=68888 GN=M513_04764 PE=4 SV=1)

HSP 1 Score: 494.197 bits (1271), Expect = 7.981e-161
Identity = 278/690 (40.29%), Postives = 406/690 (58.84%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC-------------VCINKVASL---------------NEKIRQTSFRL-----------SRQQFQYA--VLDKAEKEID----FLKCDYKDFKESLIKNPLEPIK-FSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQ+TTG+I+V +  V +  ++  Y Y+A++   Q+E C I +  +    IDL    FF  Y+ IRF+AA +K+ F   VYS VD  TIP  FV IYL+  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++F+ + + G+G  H+LEN+GD +      +   +T+ + +YF +VTM TVGYGDI   + LG++++  FIL   A+FAS++PEIA+++ S  KY G Y  +   +HIVVCG   + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F +GTVMD +DL R  + +ADAC ILAN    +P  EDAANIMRVISLKN+S  +RV++QL+QY NK+YL NIP+WN   GD V+C +E++L ILA+SCL PG+ST ++NLF++RS      F+ S N+  W+NDY+ G G+E+YT  LS S +GMTF + V   +  L LLL+A+EVK  +    T+ INP S +     T G+FI  S  E +R   YC  CH   +   + + K KC             +  N+ A +               +E  R + F             +R  F       D  + + D    F  C  +  +E +++         SNH+++C+FAD +SP IGL+NF++PLR+    +  LK
Sbjct:  149 WAGELISGQSTTGRILVVLVFVLSIGSLIIYFYDASHPNFQVETC-ISWSKSPSQQIDLAFNIFFLIYFFIRFVAATDKVWFLLEVYSFVDYFTIPPSFVAIYLERTWLGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFVSVSLTGAGFLHLLENSGDPF--QNFQNPQRITYWECVYFLVVTMGTVGYGDICCKTTLGRLFMVFFILGGLAMFASYVPEIADLIGSRQKYGGEYKAENGKRHIVVCGYITYESVSHFLQDFLHEDRDDVDVEVVFVHRVPPDLELEGLFKRHFTKVEFFQGTVMDSIDLSRVKVHKADACLILANKYSSDPDAEDAANIMRVISLKNYSPDIRVIVQLMQYHNKAYLLNIPSWNWKTGDDVICLAELKLGILAQSCLAPGFSTMMANLFAMRS------FKTSPNTPCWLNDYLRGAGMEIYTETLSHSFVGMTFPETVELIFVKLKLLLLAIEVKDDDNLECTIIINPESSAIIKVNTQGFFIAQSADEVKRAFYYCQKCHEDIQDVNM-IKKCKCRNLTLFRKGVRHIILANRTAKVLSPVERGAKEKAEEDDETERSSPFTANAIKARDVRIPARASFSSGGDKTDGNDMKYDSTGMFHWCRSRPIEEVILQREQAATTLLSNHVVICMFADKNSPLIGLRNFVMPLRASNYHYHELK 828

HSP 2 Score: 105.916 bits (263), Expect = 7.981e-161
Identity = 88/305 (28.85%), Postives = 149/305 (48.85%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXX--------------------XXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFE--NINDEEST-NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQP 2992
            +L+ ++I  + E+L REW+ L   P +  ++ N +++  L  + V  C +CVI+SAR+   N    D  L DKE IL +LN+K++                             I    +IP   L+T+L+ ++NVQFLDQ+DED+PN  ++L++ F CG AF   +LD L+S  YFN     +I   + G      E+   E  ++    ST  +     +C+I  + + +  F + F       Y +LF  A + + +LL+GLY++ E     ++   K+ ++T P     +   D V  L+P
Sbjct:  826 ELKHVVIVGDVEYLRREWKMLQNMPKITVLNGNPLSRADLRAVNVNLCDMCVIISARIPNPNE---DPTLTDKEAILASLNIKAMNFDATTAQLYHPLGNSSLNSPPMALFESKIKSGTQIP---LLTELVNDSNVQFLDQDDEDDPNTELYLTQPFTCGKAFAISVLDSLMSTTYFNDSALTLIRTFVTGGATPELEVILAEGGDLKGAPSTPQLLRKRDRCRIAQYGITEGPFVN-FGVQEGWTYGSLFLQALRKHGMLLIGLYRLQEMQPEEVT---KRFVITAPPENMKLQMTDLVFVLEP 1120

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Match: A0A1I8J2U5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 481.1 bits (1237), Expect = 3.313e-160
Identity = 284/760 (37.37%), Postives = 434/760 (57.11%), Query Frame = 1

Query:   22 CSEKKWYVFLLTNVXXXXXXXXXXXXXXXXXXXYGKIYKKLSPRNSSQGSYKAGEFSGGNNSGRXXXXXXXXXXXRVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNG-KTVFINPASQSYTTKETV-GYFICNSFKESQRVALYCNVCH---------------------------GANEGTPLRVDKFKCVCIN-KVASLNE---KIRQTSFRLSRQQF--QYAVLDKAEKEIDFLK-------CDYKDFKESLIK-NPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            CS + WY+ L +  I    GL L+LL +L+ ++  +I ++ S   S++    A   + GN      +       ++ W ++ IS Q+ TG+I+V +    +  ++G YIYEAT+    +E C + +  + L  +DL     F  Y+ IRFLAA++K+ FW  +YS+VD  T+P  FV IYL+  W+GLRF+R + +M +PD+LQYL VLKS T  R  Q+ T F+ +W++G+G+TH+ EN+GD     E ++ N +TFG+ MYFTIVTMSTVG+GD SP +  GK +++ +I+V+  IFASFIPEIAEI+ S S Y G Y  +   +H+VVCG     SI+SF+ DF +EDR  + + VV IN++ P  E ++LLK NF    +  G+V++  D +R  ++ + A  IL N   ++P  EDA+NIMRVIS+KN S   R +IQLLQY NK YL NIP W+   GD  +C +EM+   LA+SCL PG+ST ++NLFS R+ +          SW  DY +G  +E+Y+   S S +GMTF + V+  Y  L ++L A+E K   G + + INP  +S        G+F+ +S +E +R  LYCN CH                           GA+E T LR +         +VAS  +    +++T F    QQ   +Y+  D +++  ++         C  ++F++ ++K      +    H I+ +FAD+DS  IGL++F++PLR+       LK
Sbjct:   22 CSTRLWYIHLASTAIAFIGGLLLVLLVRLVGWLVKRI-RRSSQGGSTEIGKDAAMVAKGNGQTIEGDRIDWTAEVKEWANELISAQSITGRILVVLIFSLSVSSLGIYIYEATFLVGFVENC-VPWSQSVLNQVDLAFNIVFLIYFCIRFLAAQDKLWFWLEIYSIVDYCTVPPAFVNIYLNQSWLGLRFIRCLRIMTLPDVLQYLSVLKSGTVIRFFQMVTTFLSVWVIGAGITHLCENSGDP--QYEYSNVNGITFGNCMYFTIVTMSTVGFGDYSPKTDWGKFFISFYIMVALGIFASFIPEIAEIITSRSPYAGRYKKEHGRRHVVVCGAVTKESIESFLEDFLHEDREDTDVEVVCINKKAPSLEFQSLLKRNFGHLVYFIGSVLNPTDCQRVCLESSAAAIILCNKYDEDPDAEDASNIMRVISIKNVSPKTRCIIQLLQYHNKGYLLNIPNWDWRLGDECLCVAEMKQGFLAQSCLAPGFSTLMANLFSTRAMSDSHLI----GSWEKDYQDGSAMEIYSEYFSDSFVGMTFQEAVMLCYNKLRVILFAIEAKNSEGDRFLSINPPGRSAIIYNGCHGFFVADSQEEVRRAYLYCNRCHRDLADPRQIRKCSCQTEVSGPESPGHDGAHEVTRLRGNSANVRRPEIQVASRKKVLAAVQETEFGADEQQRYGEYSGDDPSKQSTEYFDLTGMFHWCPERNFEDVMLKPGSAARLNLREHYIVIVFADSDSHLIGLRSFVMPLRASNFHLRELK 773

HSP 2 Score: 116.701 bits (291), Expect = 3.313e-160
Identity = 86/303 (28.38%), Postives = 151/303 (49.83%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXE-----------------IPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPL 2995
            +L+PI+   N EFL +EW+SL  FP L+    + +N+  L   ++  C +CVIMSA+   +    +D +L+DKE++L TLN+K++         +    +                 +P   ++T++ V  N+QFLDQ+D D     ++ S+ +ACG+AFTT +LD L+S  ++N +   +I  L+ G      E+   E +     E +  +  N  +C+I   ++ D + +       +  Y  LFT   K + +L  G+Y+  ++       + K+V++TNP  EF +   D V  L P 
Sbjct:  771 ELKPIVFIGNLEFLQKEWQSLKNFPKLYMFPGSPMNRVILRSAKINLCDMCVIMSAKSKWKE--QMDPYLMDKEVVLCTLNIKAMSFADELDTSVQAQMQAFQSKDAQAKSMMSKVAVP---ILTEIFVGKNIQFLDQDDNDSDEEEIYNSQPYACGNAFTTDVLDSLMSTVFYNMNAMTLIRTLVTGGATPEMEVLMAEGLSMDGTEATPEIEANRNRCRIMQLSMLDARLRP----YGQLTYGELFTGVLKSHGILCFGVYRYRDSYNMGEPQTTKRVVVTNPPAEFRLLNSDLVYCLVPF 1064

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Match: A0A061QHQ8 (Putative calcium-activated potassium channel, slowpoke OS=Cupiennius salei OX=6928 GN=CSH_0438 PE=2 SV=1)

HSP 1 Score: 509.99 bits (1312), Expect = 5.969e-160
Identity = 299/791 (37.80%), Postives = 447/791 (56.51%), Query Frame = 1

Query:   28 EKKWYVFLLTNVXXXXXXXXXXXXXXXXXXXYGKIYKKLSPRNSSQGSYKAGEFSGGNNSGRXXXXXXXXXXXRVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNG--KTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH---------------------------GANEGTPLRVDKFKCVCINKVASLNEKI-RQTSFRLSRQQFQYAVLDKAEKEIDFLK-------------CDYKDFKESLI-KNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK-------TDYYSEQ*GISPQRMEIFSVFSKSP 2247
            E+KW+ FLL+++I    GLF++L+W+   FI  +  KK     ++  S       GGNN  R   E   +   + W  + ISGQ TTG+I+V +  + +  ++  Y  +A+    ++E C  + E      IDL    FF  Y+ IRF+AA +K+ F   +YS VD  TIP  F+ IYL   W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++ I +W+  +G+ H+LEN+GD     + ++ N +T+   +YF IVTMSTVGYGDI   + LG+ ++ +FILV  A+FAS+IPEI E++   SKY G    +   +HIVVCG+  + S+  F+ DF +EDR    + VVF++++ PD EL  L K +F   +F +GTVM+ VDL+R  + +ADAC +LAN  C++P  EDAANIMRVIS+KNFS  +RV+IQL+QY NK+YL NIP+WN   GD V+C +E++L  +A+SCL PG+ST ++NLF++RS     +      +W NDY+ G G+E+YT  LS S +GM+F       +  L LLL+A+EV   +G    + INP SQ   T +T G+FI  S  E +RV  YC  CH                           G  + +P +V+    +   +         R +S  ++ + F     D+  K+ DF +             C  +  ++ ++ +N       + H++LC+FAD DSP IGL+N ++PLR+    +  LK        DY   +  +  Q +   S+ S SP
Sbjct:   17 ERKWWCFLLSSIITFLVGLFIILIWRAFAFICCR--KKTGDSQAATKSKVPDSKGGGNN--REVAEIGFMTEAKDWAGELISGQTTTGRILVVLVFLLSIASLIIYFIDAS--KDKVETCHSWSENT-TQQIDLALNIFFMVYFFIRFIAASDKLWFMLELYSFVDYFTIPPSFISIYLGRTWIGLRFLRALRLMSVPDILQYLNVLKTSSSIRLAQLVSIVISVWLTAAGIIHLLENSGD---PLDFSNPNEMTYWQCVYFLIVTMSTVGYGDIYCQTSLGRGFIVLFILVGLAVFASWIPEITELIGHPSKYGGVLRKERGKRHIVVCGHINYDSVSYFLKDFLHEDREDVDVEVVFLHRKPPDLELEGLFKRHFTTVEFFQGTVMNPVDLQRVKVHQADACLVLANKYCQDPDAEDAANIMRVISIKNFSDDIRVIIQLMQYHNKAYLLNIPSWNWKNGDDVICLAELKLGFIAQSCLAPGFSTMVANLFAMRSYKTSPD----TPAWQNDYLCGTGMEMYTETLSTSFVGMSFPQAAELCFVKLKLLLLAIEVTHDDGTDSKISINPKSQVKLTPDTQGFFIAQSADEVKRVWYYCKNCHEDVKDEKQIKKCKCKIPPASSVVLPRNGNRQKSPGKVNSMSSISSARKGRHGRPTGRNSSGSVTERPFGIMAEDQG-KDFDFERTEMKYDSTGMFHWCPARSIEDCILDRNQAAMTVLNGHVVLCLFADKDSPLIGLRNLVMPLRASNFHYHELKHVVIVGNVDYLRREWKML-QNLPKISILSGSP 791

HSP 2 Score: 92.8189 bits (229), Expect = 2.966e-15
Identity = 90/303 (29.70%), Postives = 153/303 (50.50%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXX--------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG------EIHCFENI---NDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ ++I  N ++L REW+ L   P +  +S + +++  L  + +  C +CVI+SA++     ++ D  L DKE IL +LN+K++                                S    N  LIT+L+ + NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN +   +I  LI G      E+   E         +    NN  +C++   +L D    S +    +  Y ++F  A K+Y +L +GLY+  +T+ +  +S+K+ VI TNP  +F +   D V  L
Sbjct:  758 ELKHVVIVGNVDYLRREWKMLQNLPKISILSGSPLSRADLRAVNINLCDMCVILSAKI----PSSEDPTLADKEAILASLNIKAMTFDDTIGVLTHHETGREGMSPLGSPIVLQRRGSVYGTNVPLITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNANALTLIRSLITGGATPELELILAEGAGLRGGYSTPESLNNRDRCRVGQISLSDGPLAS-YGEGGK--YGDVFVKALKNYGMLCIGLYRYRDTSSSFEASTKRYVI-TNPPADFPLIPSDKVFVL 1052

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BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Match: A0A0V1EKP6 (Calcium-activated potassium channel slo-1 OS=Trichinella pseudospiralis OX=6337 GN=slo-1 PE=4 SV=1)

HSP 1 Score: 486.108 bits (1250), Expect = 2.160e-158
Identity = 278/701 (39.66%), Postives = 405/701 (57.77%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNS--WINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK--TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN------------------KVASLNEKIRQ---------------------TSFRLSRQQFQYAVLDKAEKEID-FLKCDYKDFKESLI-------KNPLEPIKFS----------NHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQ+TTG+I+V +  V +  ++  Y Y+A++   Q+E C I +  +    IDL    FF  Y+ IRF+AA +K+ F   VYS +D  TIP  FV IYL+  W+GLRFLRA+ LM VPD+LQYL VLK+++  RL QL ++F+ + + G+G  H+LEN+GD +      +   +T+ + +YF +VTM TVGYGDI   + LG+ ++  FIL   A+FAS++PEIA+++ S  KY G Y  +   +HIVVCG   + S+  F+ DF +EDR    + VVF+++  PD EL  L K +F + +F +GTVMD +DL R  + +ADAC ILAN    +P  EDAANIMRVISLKN+S  +RV++QL+QY NK+YL NIP+WN   GD VVC +E++L I+A+SCL PG+ST ++NLF++RS      F+ S ++  W+NDY+ G G+E+YT +LS S +GMTF +     +  L LLL+A+E+K        + INP S       T G+FI  S  E +R   YC  CH  ++   + + K KC C N                  KV S NE+ ++                     +S R +    +  + D  +   D + + D +D K             P+E I             NH++LC+FAD  SP IGL+NF++PLR+    +  LK
Sbjct:  153 WAGELISGQSTTGRILVVLVFVLSIGSLIIYFYDASHPNFQVETC-ISWSHSPSQQIDLAFNIFFLIYFFIRFVAATDKVWFLLEVYSFIDYFTIPPSFVAIYLERTWLGLRFLRALRLMTVPDILQYLNVLKTSSSIRLAQLVSIFVSVSLTGAGFIHLLENSGDPF--QNFQNPQRITYWECVYFLVVTMGTVGYGDICCKTLLGRFFMVFFILGGLAMFASYVPEIADLIGSRQKYGGEYKAENGKRHIVVCGYITYESVTHFLQDFLHEDRDDVDVEVVFLHRVPPDLELEGLFKRHFTKVEFFQGTVMDSIDLSRVKVHKADACLILANKYSSDPDAEDAANIMRVISLKNYSPEIRVIVQLMQYHNKAYLLNIPSWNWRTGDDVVCLAELKLGIIAQSCLAPGFSTMMANLFAMRS------FKTSMSTPGWLNDYLRGAGMEIYTESLSHSFVGMTFPETAELMFTRLKLLLLAIEIKDDESLECNIIINPESNVIIKVNTQGFFIAQSADEVKRAFYYCQKCH--DDVLDVNLIK-KCKCRNLTLFRKGVRHVILANRTAKVLSPNERSQRSSLDDRNKGNLIEGTSEIDLKSSLREAGLPLKVGLSDPDDGSNDPWQRIDEEDMKYDSTGMFHWCKARPIEDIILDREQASVTLLHNHVVLCLFADRHSPLIGLRNFVMPLRASNYHYHELK 841

HSP 2 Score: 105.531 bits (262), Expect = 2.160e-158
Identity = 83/305 (27.21%), Postives = 146/305 (47.87%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXX-------XXXXXXXXXXXXXEIPNRFL-------------ITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDE--------ESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQP 2992
            +L+ ++I  + E+L REW+ +   P +  ++ N +++  L  + +  C +CVI+SAR+   N    D  L DKE IL +LN+K++                I  +   P+  L             +T+L+ ++NVQFLDQ+DED+PN  ++L++ F CG AF   +LD L+S  YFN     +I  L+  G     E I  E         ++ +     +C+I  + + DD   +     +   Y  LF    +   +L +GLY++ E      ++S K+ ++T+P     +   D +  L+P
Sbjct:  839 ELKQVVIVGDVEYLRREWKMIQNLPKIIILNGNPLSRADLRAVNINMCDMCVIISARIPNPNE---DPTLTDKEAILASLNIKAMNFDECSPNLTAAMSGNILVNSRSPSMMLCSNPIRSGTEILMLTELVNDSNVQFLDQDDEDDPNTELYLTQPFTCGKAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELEGILAEGGDLRGAPSTSQLLRKRDRCRIAQYGINDDGPFAGLNIQDNYTYGRLFIKVLRERRMLCIGLYRLQEPPP---ATSGKRFVITSPPENMKLMITDRIFVLEP 1137

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Match: kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a [Source:ZFIN;Acc:ZDB-GENE-070202-9])

HSP 1 Score: 440.269 bits (1131), Expect = 4.097e-140
Identity = 234/649 (36.06%), Postives = 372/649 (57.32%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ------TSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K    + ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C        ++L+ K +Q       S   S +     +  ++E  +  L                     S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:   41 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQNFYKD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPTVCELCYVKLKLLLIAIEYKSEQRESSILINPGNHVKMQEGTLGFFIASDAKEVKRAFFYCKACHD-DITDPKRIKKCGCKRFEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSMFLNTRSEASMTVL---------------------SGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 656

HSP 2 Score: 79.7221 bits (195), Expect = 4.097e-140
Identity = 89/315 (28.25%), Postives = 153/315 (48.57%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGL 2986
            +L+ I+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D +  L
Sbjct:  654 ELKHIVFVGSLDYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGLVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLTAPSPCTKRYVITNPPYEFELVPTDLIFCL 956

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Match: ENSAMXT00000050702.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000050702.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 445.277 bits (1144), Expect = 4.249e-138
Identity = 243/665 (36.54%), Postives = 382/665 (57.44%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKV--ASLNEKIRQ------TSFRLSRQQF-----------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C I+ E    L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K  +   +  INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C    +V  ++L+ K +Q      TS   S +             Q   +D   K+ D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  115 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIESCQIFDED-ITLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPGNHVKMQEGTLGFFIASDAKEVKRALYYCKACHD-DITDPKRIKKCGCKRFEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHDQMETMDVNVKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELK 767

HSP 2 Score: 60.4622 bits (145), Expect = 9.262e-9
Identity = 57/174 (32.76%), Postives = 97/174 (55.75%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  921 MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTD 1090

HSP 3 Score: 52.7582 bits (125), Expect = 2.179e-6
Identity = 29/83 (34.94%), Postives = 48/83 (57.83%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNV 2410
            +L+PI+   + E+L REW +L  FP +  +  + +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+
Sbjct:  765 ELKPIVFVGSLEYLKREWETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNI 842

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Match: ENSAMXT00000044980.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000044980.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 442.58 bits (1137), Expect = 6.327e-137
Identity = 241/678 (35.55%), Postives = 382/678 (56.34%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLN------EKIRQTSFRLSRQQF--------------------------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C I+ E    L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K  +   +  INP +     + T+G+FI +  KE +R   YC  CH  +   P R+   KC C    ++ N      E++ Q++    ++Q                           Q   +D   K+ D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  115 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIESCQIFDED-ITLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPGNHVKMQEGTLGFFIASDAKEVKRALYYCKACHD-DITDPKRIK--KCGCKRSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHDQMETMDVNVKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELK 778

HSP 2 Score: 60.4622 bits (145), Expect = 9.524e-9
Identity = 57/174 (32.76%), Postives = 97/174 (55.75%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  932 MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTD 1101

HSP 3 Score: 52.7582 bits (125), Expect = 2.278e-6
Identity = 29/83 (34.94%), Postives = 48/83 (57.83%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNV 2410
            +L+PI+   + E+L REW +L  FP +  +  + +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+
Sbjct:  776 ELKPIVFVGSLEYLKREWETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNI 853

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Match: ENSAMXT00000050440.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:48528:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000050440.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 441.425 bits (1134), Expect = 1.207e-136
Identity = 239/678 (35.25%), Postives = 381/678 (56.19%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLN------EKIRQTSFRLSRQQF--------------------------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C I+ E    L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FA ++PEIA ++ +  KY G+Y      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K  +   +  INP +     + T+G+FI +  KE +R   YC  CH  +   P R+   KC C    ++ N      E++ Q++    ++Q                           Q   +D   K+ D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  115 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIESCQIFDED-ITLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGTYNSTRGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPGNHVKMQEGTLGFFIASDAKEVKRALYYCKACHD-DITDPKRIK--KCGCKRSKSNYNGYIKSIEEVHQSTLSPKKKQRNGGMRTSPNCSPKNLRHDPLLIPSHDQMETMDVNVKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELK 778

HSP 2 Score: 60.4622 bits (145), Expect = 9.579e-9
Identity = 57/174 (32.76%), Postives = 97/174 (55.75%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +   D
Sbjct:  932 MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFELVPTD 1101

HSP 3 Score: 52.7582 bits (125), Expect = 2.216e-6
Identity = 29/83 (34.94%), Postives = 48/83 (57.83%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNV 2410
            +L+PI+   + E+L REW +L  FP +  +  + +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+
Sbjct:  776 ELKPIVFVGSLEYLKREWETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNI 853

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Match: ENSAMXT00000051878.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000822.1:37062:202682:-1 gene:ENSAMXG00000004398.2 transcript:ENSAMXT00000051878.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 418.313 bits (1074), Expect = 1.099e-127
Identity = 212/543 (39.04%), Postives = 330/543 (60.77%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC 1878
            W    IS Q  TG+++V +    +   +  Y  +++     IE C I+ E    L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K  +   +  INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C
Sbjct:  115 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIESCQIFDED-ITLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQPLSYWECVYLLMVTMSTVGYGDVCAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCYVKLKLLLIAIEYKSDQRESSTLINPGNHVKMQEGTLGFFIASDAKEVKRALYYCKACHD-DITDPKRIKKCGC 645

HSP 2 Score: 87.0409 bits (214), Expect = 4.762e-23
Identity = 89/306 (29.08%), Postives = 153/306 (50.00%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXX------------------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSV 2959
            +L+PI+   + E+L REW +L  FP +  +  + +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   +  S   K+ ++TNP  EF +
Sbjct:  831 ELKPIVFVGSLEYLKREWETLHNFPKVSILPGSPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMLFDDSIGLLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLSAPSQCTKRYVITNPPYEFEL 1124

HSP 3 Score: 41.9726 bits (97), Expect = 4.762e-23
Identity = 24/78 (30.77%), Postives = 39/78 (50.00%), Query Frame = 1

Query: 1954 QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            Q   +D   K+ D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  756 QMETMDVNVKKYDSTGMFHWCPSKDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSAVVGLRNLVMPLRASNFHYHELK 833

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006399.1 (pep scaffold:Pmarinus_7.0:GL477091:41003:110164:-1 gene:ENSPMAG00000005728.1 transcript:ENSPMAT00000006399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 311.997 bits (798), Expect = 1.995e-97
Identity = 151/383 (39.43%), Postives = 240/383 (62.66%), Query Frame = 1

Query:  736 ENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN--GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC 1878
            EN+GD W   + N +N LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FA ++PEIA ++ +  KY G Y+P    KH+VVCG+    S+ +F+ DF ++DR    + ++F++   P+ EL  L + +F + +F +G+V++ +DL R  I+ ADAC I+AN  C +P  EDA+NIMRVIS+KN+   +RV+ Q+LQY NK++L NIP+W+  +GD  +C SE++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LLLIA+E +  +  G ++ +NP S       T+ +FI N  KE +R   YC  CH  +   P ++ K  C
Sbjct:    1 ENSGDPWRDFQ-NQQN-LTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRRKYGGEYLPTRGRKHVVVCGHITLESVSNFLKDFLHKDRDDVNVEILFLHSISPNLELEALFRRHFTQVEFYQGSVLNPLDLARVKIEAADACMIIANKYCPDPDAEDASNIMRVISIKNYHPRIRVITQMLQYHNKAHLLNIPSWSWREGDAAICLSELKLGFIAQSCLAQGISTMLANLFSMRSYIKIEE-----DTWQKFYLEGVSNEMYTEYLSSAFVGLSFPAVSELCFVKLRLLLIAIEYRSEHSYGSSILLNPGSHVRIQDGTLAFFIANDSKEVKRAFYYCKACH-EDVTDPKKIKKCSC 375

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006404.1 (pep scaffold:Pmarinus_7.0:GL477091:42221:110230:-1 gene:ENSPMAG00000005728.1 transcript:ENSPMAT00000006404.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 312.383 bits (799), Expect = 2.266e-97
Identity = 149/384 (38.80%), Postives = 240/384 (62.50%), Query Frame = 1

Query:  733 LENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRN--GKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKC 1878
            +EN+GD W   +  ++  LT+ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FA ++PEIA ++ +  KY G Y+P    KH+VVCG+    S+ +F+ DF ++DR    + ++F++   P+ EL  L + +F + +F +G+V++ +DL R  I+ ADAC I+AN  C +P  EDA+NIMRVIS+KN+   +RV+ Q+LQY NK++L NIP+W+  +GD  +C SE++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    +  L LLLIA+E +  +  G ++ +NP S       T+ +FI N  KE +R   YC  CH  +   P ++ K  C
Sbjct:   22 VENSGDPW--RDFQNQQNLTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRRKYGGEYLPTRGRKHVVVCGHITLESVSNFLKDFLHKDRDDVNVEILFLHSISPNLELEALFRRHFTQVEFYQGSVLNPLDLARVKIEAADACMIIANKYCPDPDAEDASNIMRVISIKNYHPRIRVITQMLQYHNKAHLLNIPSWSWREGDAAICLSELKLGFIAQSCLAQGISTMLANLFSMRSYIKIEE-----DTWQKFYLEGVSNEMYTEYLSSAFVGLSFPAVSELCFVKLRLLLIAIEYRSEHSYGSSILLNPGSHVRIQDGTLAFFIANDSKEVKRAFYYCKACH-EDVTDPKKIKKCSC 397

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007042.1 (pep scaffold:Pmarinus_7.0:GL486096:7796:16492:-1 gene:ENSPMAG00000006371.1 transcript:ENSPMAT00000007042.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 196.438 bits (498), Expect = 1.345e-57
Identity = 91/215 (42.33%), Postives = 140/215 (65.12%), Query Frame = 1

Query: 1000 KHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKS--GNSWINDYINGMGLELYTSNLSLSLIGMTF 1638
            +HIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +RV+ Q+ QY NK++L NIP+WN  +GD  +C +E++L  +A+SCL PG ST ++NLFS+RS  +          ++W   Y+ G+  E+YT  LS +  G++F
Sbjct:    1 RHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIEAADACLILANKYCGDPDAEDASNIMRVISIKNYHPRIRVITQMQQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAPGLSTMLANLFSMRSYIKRVPLPHQIEEDTWQKYYLEGVSNEMYTEYLSNAFTGLSF 215

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Match: KCNT1 (potassium sodium-activated channel subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:18865])

HSP 1 Score: 97.0561 bits (240), Expect = 1.688e-21
Identity = 64/236 (27.12%), Postives = 115/236 (48.73%), Query Frame = 1

Query:  679 LSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSY--VPKEEYKHIVVC-GNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNF--MRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENK 1371
            + T+F  M+    G  H LE   +            ++   S+YF IVT STVG+GD+ P  +  ++ V I I V+  +      E+  +     K  G+Y     +  KH+V+C  + +   +  F+ +F+   R +     V +   + D ++R +L +     R  +++G+ +   DL R  ID+A+ACFIL + N  +    D   I+R  ++K+F+ S  + +Q+L+ ENK
Sbjct:  198 ICTLFCLMFTFICGFQH-LERAAEN-----------ISLFRSLYFCIVTFSTVGFGDVLPKIWPSQLLVVIMICVALMVLPVQFEELVYLYMERQKSGGNYSRYRAQTEKHVVLCVSSLKLDLLMDFLNEFYAHPR-LQDFYTVILCPTDMDSQVRRMLHVPLWAQRVIYLQGSALKDQDLVRVKIDDAEACFILTSRNEVDRTAADHQTILRAWAVKDFAPSCPLYVQILKPENK 420

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001869.1 (pep scaffold:Pmarinus_7.0:GL480351:152:3521:-1 gene:ENSPMAG00000001700.1 transcript:ENSPMAT00000001869.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.9442 bits (180), Expect = 3.174e-14
Identity = 62/236 (26.27%), Postives = 106/236 (44.92%), Query Frame = 1

Query:  289 GKIIVFIACVCTFITVGDYIYEATYFP--MQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLD----------------HLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWI-VGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEI 939
             K++  I+ +  FI +          P   + +  G   +   L  ++  C ++FT  Y++RFL++ NK +F+ G  +++DLL I  +++ I+L                  ++  +R LR + L +    LQ LG     +   LG L  +F+ M I + S +    E   D        D  F +   S ++  +TM+TVGYGDI P + LGKI   +  +    + A  IP I
Sbjct:    1 AKVLAIISIL--FIVLSTIALSLNTLPDLQETDEYGNVMDNPSLAHVEAVCIAWFTTEYMLRFLSSPNKWKFFKGALNVIDLLAILPYYITIFLTESNHSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLL-ILFLAMGIMIFSSLVFFAEKDED--------DTKFRSIPASFWWATITMTTVGYGDIYPQTLLGKIVGGLCCIAGVLVIALPIPII 225

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Match: EDO32743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU69])

HSP 1 Score: 119.398 bits (298), Expect = 2.608e-27
Identity = 109/443 (24.60%), Postives = 205/443 (46.28%), Query Frame = 1

Query:  526 LLTIPSFFVEIYLDHL---WMGLRFLRAIWLMQVP------DLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSY--VPKEEYKHIVVCG-NFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNF--MRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGM-----TFYDLVLFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFICNSFKE 1797
            +L++P F + I++  L   W+ L FL   WL +        DL + +   +SA   ++  L T  +C+        H LE     W           +   +++F IVT STVGYGD  P  +  + +V I I ++  +    +  +A +LFS  K  G+Y  +     +H+V+C       ++  F+ +F+ + R +  ++VV +   + D  LR LL++     R  ++KG+ +   DL RA  + A  CFILA+    + +  D   I+R  ++++F+ +  + +Q+L+ ENK +++          + VVC  E++  +LA +C+ PG    IS L ++      +++ +    W   Y    G E+Y   L  S+I       +F      +++   + LI V+   + G+ + +NP        +   ++I  S +E
Sbjct:  168 ILSVP-FLISIFMSELRNIWIPL-FLNC-WLAKAALETMFNDLHRLVLHQQSALSQKVLILITTVVCILFTSVCGIHHLERASLQW-----------SMMKTLWFVIVTFSTVGYGDTVPTHWTTQTFVMIMIGIALVLLPIELERLAFLLFSRQKEGGAYNHLLAGTDRHVVLCATTLRTGTLIDFLNEFYADSR-LHDVHVVLLCPSDLDSTLRILLQVPVWAQRVTYLKGSALIDEDLVRARRNAA-GCFILADRYAADREAADQHTILRTWAIQDFAPATPLFVQILKPENKFHVSF--------AEHVVCEDEIKHALLAVNCVCPG----ISTLVTLLLHTLHEQYVRGSEKWHEIYGKCAGNEIYDIRLGDSMIFRPYAYKSFTHAAFHAHKKYGVTLIGVKRHGKGGR-LMLNPGPSHNMAYDDRCFYIAISSEE 581

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Match: EDO46156 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQS3])

HSP 1 Score: 77.0258 bits (188), Expect = 8.798e-15
Identity = 57/226 (25.22%), Postives = 114/226 (50.44%), Query Frame = 1

Query:  289 GKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLR---AIWLMQVPDLLQYLGVLKSATKFR-LGQ-LSTMF--ICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAE 945
            GKI+  +  +  +++V   I E     +  + C   +   F  A+D FC   FT  YI+R  AAEN  EF     +++D+L +  F++ + +  + +  + L    ++ ++++  + +   + + + K R +G  L + F  +   I    + ++L  +   ++  + + + F +  DSM++TI+TM TVGYGD  P + LGK+  ++  L+   + A  IP + E
Sbjct:  153 GKIVQTLIAILIYVSVAASIVETLQCSLG-KTCEETHPTIFF-ALDAFCMITFTLEYILRLFAAENMREFLTNKLNILDVLAVAPFYILLCVREIELSQQMLENANSLVILRILRMFRIFKLSRHSRKMRKMGHALKSAFSDLGFLIFAFLLANVLFASVLYFIERDTSPQQFTSIPDSMWYTIITMMTVGYGDAVPVTVLGKVVGSVCALLGIIMLALPIPILQE 376

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Match: SHAK6 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFM4])

HSP 1 Score: 70.0922 bits (170), Expect = 1.181e-12
Identity = 53/167 (31.74%), Postives = 86/167 (51.50%), Query Frame = 1

Query:  418 AIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLW--MGLRFLRAIWLMQVPDL---------LQYLGVLKSATKFRLGQLSTMFICMWIV--GSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKI 879
            AI+ FC ++FT  Y IRFL + +K +F   V +L+DL+ I  FF+ + +        L  LR + L++V  +         LQ LG    A+   LG L   F+C+ ++   S + +   N           D  FL+   S +++I+TM+TVGYGD++P +  GK+
Sbjct:  184 AIESFCIAWFTLEYFIRFLCSPDKCKFVVSVLNLIDLVAILPFFITLPMTEPTSVSSLAILRCVRLVRVFRIFKLSRYSRGLQILGHTLKASLRELGLL-FFFLCVGVILFSSAVYYAEYNYN--------RDTEFLSIPHSFWWSIITMTTVGYGDMAPKTLGGKL 341

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Match: EDO31311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYB8])

HSP 1 Score: 70.4774 bits (171), Expect = 1.308e-12
Identity = 58/242 (23.97%), Postives = 108/242 (44.63%), Query Frame = 1

Query:  247 RVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIER-CGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMG------------LRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIP 933
            RVW        ++ GKI   +  +   +++   I E    P    R CG  +  AF + +D  C   FT  Y++R L+A  +  F     S++D+ ++  F+++I  + +  G             R  R + + +    LQ LG     +   LG +   F    ++ + + +  E         E+N  +FL+  D M++ IVTM+T GYGD++P + +G++  +   +V   + A  +P
Sbjct:  173 RVWDLFENPYNSSLGKITYAVTGIAIIVSILTTITET--IPCSTTRTCGELHASAFFI-VDGVCVGIFTLEYLVRLLSAPERWPFVKNFQSIIDVASVMPFYLDILFEQISGGSSGAEGLTILRVFRVFRVVKMSRHSKRLQSLGASIKNSSSELGFILFSFSLGVVIFATVIYYCEKD-------ELN-TSFLSIPDGMWYAIVTMTTTGYGDMTPETAIGQLMGSFCCIVGTLVIALPVP 403

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Match: SHAKR12 (Potassium channel; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI05])

HSP 1 Score: 67.781 bits (164), Expect = 9.162e-12
Identity = 46/166 (27.71%), Postives = 82/166 (49.40%), Query Frame = 1

Query:  418 AIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLD------------HLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKI 879
             ID    ++FT  YI R ++A +K++F F   +L+DL+ I  +F+ + LD             ++  LR +R + L +    L+ LG    + + +L  L  + +   I+ S + + LEN        E N   F +   + ++ I+TM+TVGYGD  P +  G++
Sbjct:  208 VIDTCIITWFTSEYIARLISAPHKLKFVFSTLALIDLIAIIPYFISLGLDADQTHAITFTVLRIFRLLRVIRLLKLTRYVAALRILGYTIQSCQDQLTALMFLLLISIILFSSLMYYLEN--------EENPTEFYSIPAAFWWCIITMTTVGYGDTCPRTPFGRL 365

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 444.891 bits (1143), Expect = 4.480e-143
Identity = 242/666 (36.34%), Postives = 379/666 (56.91%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN----KVASLNEKIRQTSFR---------LSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K    + ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +        S  +K R    R         +SR          Q   +D   K  D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  141 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQSFYDD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESSILINPGNHVKMQEGTLGFFIASDAKEVKRAFYYCKACHD-DITDPKRIKKCGCKRLEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMNIKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 794

HSP 2 Score: 85.1149 bits (209), Expect = 4.480e-143
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSV 2959
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +
Sbjct:  792 ELKPIVFVGSLDYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEL 1085

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BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Match: ENSORLT00000011055.2 (potassium calcium-activated channel subfamily M alpha 1 [Source:NCBI gene;Acc:101155390])

HSP 1 Score: 445.662 bits (1145), Expect = 3.037e-142
Identity = 241/665 (36.24%), Postives = 385/665 (57.89%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKM-RNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCI--NKVASLNEKIRQ----------TSFRLSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +  Y  +++     IE C  +Y   + L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++L  +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K  +   +  INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C     ++ ++L+ K +Q          +S ++ R          Q   +D+  K+ D    F  C  +D ++  L ++       S H+++CIF D  S  IGL+NF++PLR+    +  LK
Sbjct:  111 WAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSD---PIEFCKHFYSN-YTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQALSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEE-----DTWQKYYLEGVSNEMYTEYLSSAFVGLSFPVICELCYVKLKLLLIAIEYKSDQRESSTLINPGNHVKMQEGTLGFFIASDAKEVKRALFYCKACHD-DISDPKRIKKCGCKKFEEDRHSALSPKKKQRNGGMRNSPNSSPKIMRHDPLFIPGSEQIESMDENVKKYDSTGMFHWCPSRDIEKVILTRSEAAMTVLSGHVVVCIFGDVKSALIGLRNFVMPLRASNFHYHELK 763

HSP 2 Score: 81.6481 bits (200), Expect = 3.037e-142
Identity = 88/306 (28.76%), Postives = 150/306 (49.02%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLD-FHLVDKEIILGTLNVXXX------------------------------XXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSV 2959
            +L+ I+   + E+L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+D   L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +   N  S   K+ ++TNP   F +
Sbjct:  761 ELKHIVFVGSLEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIDDASLQDKECILASLNIKSMLFDDSIRVLQANSQGFTPPGMDRSSPENSPVHGLVRQTSVTTGANIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALKGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLNAQSQCTKRYVITNPPYAFEL 1054

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 437.187 bits (1123), Expect = 1.210e-140
Identity = 246/697 (35.29%), Postives = 381/697 (54.66%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK-----MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDK-------------------------FKCVC------INKVASLNEKIRQTSFR---------LSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K      R+ K + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K                         FK  C           S  +K R    R         +SR          Q   +D   K  D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  141 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQSFYDD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESRSRKRILINPGNHVKMQEGTLGFFIASDAKEVKRAFYYCKACHD-DITDPKRIKKCGCKRPAEGATTPGNTGSQKEAGVRFKADCNIVEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMNIKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 825

HSP 2 Score: 84.7297 bits (208), Expect = 1.210e-140
Identity = 89/310 (28.71%), Postives = 152/310 (49.03%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D
Sbjct:  823 ELKPIVFVGSLDYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSD 1120

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 447.588 bits (1150), Expect = 3.193e-138
Identity = 244/670 (36.42%), Postives = 380/670 (56.72%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK-----MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN----KVASLNEKIRQTSFR---------LSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FAS++PEI E++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMRVIS+KN+   +R++ Q+LQY NK++L NIP+WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K      R+ K + INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +        S  +K R    R         +SR          Q   +D   K  D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  141 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQSFYDD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVNGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESRSRKRILINPGNHVKMQEGTLGFFIASDAKEVKRAFYYCKACHD-DITDPKRIKKCGCKRLEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMNIKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 798

HSP 2 Score: 60.4622 bits (145), Expect = 1.044e-8
Identity = 57/174 (32.76%), Postives = 96/174 (55.17%), Query Frame = 2

Query: 2480 LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYD 2971
            +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +   D
Sbjct:  952 MITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFELVPSD 1121

HSP 3 Score: 51.6026 bits (122), Expect = 5.294e-6
Identity = 28/83 (33.73%), Postives = 47/83 (56.63%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNV 2410
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+
Sbjct:  796 ELKPIVFVGSLDYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIEDASLQDKECILASLNI 873

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Match: kcnma1a (calcium-activated potassium channel subunit alpha-1 [Source:NCBI gene;Acc:101174692])

HSP 1 Score: 391.734 bits (1005), Expect = 4.709e-127
Identity = 226/666 (33.93%), Postives = 354/666 (53.15%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCIN----KVASLNEKIRQTSFR---------LSRQQF-------QYAVLDKAEKEID----FLKCDYKDFKES-LIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W    IS Q  TG+++V +    +   +G Y  +++     IE C  +Y+  F L ID+    FF  Y+ +RF+AA +K+ FW  V S+VD  T+P  FV +YL+  W+GLRFLRA+ L+Q  ++LQ+L +LK++   +L  L ++FI  W+  +G  H++EN+GD W      +   L++ + +Y  +VTMSTVGYGD+   + LG++++  FIL   A+FA ++PEIA ++ +  KY GSY      KHIVVCG+    S+ +F+ DF ++DR    + +VF++   P+ EL  L K +F + +F +G+V++  DL R  I+ ADAC ILAN  C +P  EDA+NIMR                          T    WN  +GD  +C +E++   +A+SCL  G ST ++NLFS+RS  + +E     ++W   Y+ G+  E+YT  LS + +G++F  +    Y  L LLLIA+E K    + ++ INP +     + T+G+FI +  KE +R   YC  CH  +   P R+ K  C  +        S  +K R    R         +SR          Q   +D   K  D    F  C  KD ++  L ++       S H+++CIF D  S  +GL+N ++PLR+    +  LK
Sbjct:  141 WAGVMISAQTLTGRVLVVLVFALSIGALGIYFIDSSD---PIESCQSFYDD-FTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPW--ENFQNSQSLSYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFARYVPEIAALILNRKKYGGSYNSTRGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCGDPDAEDASNIMR-------------------------YTLYHIWNWKEGDDAICLAELKAGFIAQSCLAQGLSTMLANLFSMRSFIEIEE-----DTWQKYYLEGVANEMYTEYLSSAFVGLSFPHICELCYVKLKLLLIAIEYKSEQRESSILINPGNHVKMQEGTLGFFIASDAKEVKRAFYYCKACHD-DITDPKRIKKCGCKRLEDEHPSTLSPKKKQRNGGMRNSPNCSPKMMSRHDPLLIPGNEQIENMDMNIKRYDSTGMFHWCPSKDIEKVILTRSEASMTVLSGHVVVCIFGDVTSALVGLRNLVMPLRASNFHYHELK 769

HSP 2 Score: 85.1149 bits (209), Expect = 4.709e-127
Identity = 88/306 (28.76%), Postives = 151/306 (49.35%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANL-DFHLVDKEIILGTLNVXXXX------------------------------XXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEEST---------NMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSV 2959
            +L+PI+   + ++L REW +L  FP +  +    +++  L  + +  C +CVI+SA     N  N+ D  L DKE IL +LN+KS+                                  +++  +     IP   +IT+L+ ++NVQFLDQ+D+D+P+  ++L++ FACG+AF   +LD L+S  YFN ++  +I  L+  G     E +  EE+           +AN + +C++    L+D  F         C Y +LF  A K Y++L  G+Y++ +      S   K+ ++TNP  EF +
Sbjct:  767 ELKPIVFVGSLDYLRREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSA-----NQNNIEDASLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDSSPVHGFVRQASVTTGSNIP---IITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEGLLAEENALRGGYSTPQTLANRD-RCRVAQLALYDGPFADL--GDGGC-YGDLFCKALKTYNMLCFGIYRLRDAHLGAPSQCTKRYVITNPPYEFEL 1060

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Match: SMESG000014623.1 (SMESG000014623.1)

HSP 1 Score: 1391.71 bits (3601), Expect = 0.000e+0
Identity = 710/720 (98.61%), Postives = 714/720 (99.17%), Query Frame = 1

Query:   13 MPKCSEKKWYVFLLTNVXXXXXXXXXXXXXXXXXXXYGKIYKKLSPRNSSQGSYKAGEFSGGNNSGRXXXXXXXXXXXRVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            MPKCSEKKWYVFLLTNVIIIFSGLFLLLLWKLIKFIYGKI KKLSP N+SQGSYKAGEFSGGNNSGRINEENQNIQIIRVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYA+LDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKK   + L+
Sbjct:    1 MPKCSEKKWYVFLLTNVIIIFSGLFLLLLWKLIKFIYGKISKKLSPINASQGSYKAGEFSGGNNSGRINEENQNIQIIRVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAILDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKLDTADLR 720

HSP 2 Score: 526.168 bits (1354), Expect = 1.656e-170
Identity = 292/292 (100.00%), Postives = 292/292 (100.00%), Query Frame = 2

Query: 2147 KKLDTADLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAGEIHCFENINDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXXXXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPLSQCDFTITN 3022
            KKLDTADLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVKSIFKKKLQKKFIGKSGEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAGEIHCFENINDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFKHYHLLLLGLYKVVETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPLSQCDFTITN
Sbjct:  712 KKLDTADLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVKSIFKKKLQKKFIGKSGEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAGEIHCFENINDEESTNMANNNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFKHYHLLLLGLYKVVETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPLSQCDFTITN 1003

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Match: SMESG000044594.1 (SMESG000044594.1)

HSP 1 Score: 545.428 bits (1404), Expect = 2.956e-177
Identity = 274/656 (41.77%), Postives = 420/656 (64.02%), Query Frame = 1

Query:  247 RVWTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK--MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGA-NEGTPLRV-------DKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKA----EKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            R + ++ IS Q   G+I+  IA V   ++   Y+YE    P+++E+C  Y     +   DL C   F  Y+++RF  +  K+ FW G ++++D  TIP     + LD  W+GLRF+R + L++V +++Q   V+KS T  R+ QL T F  + IVG+G  H+LEN+G+    +  N+   + +GDS+YF IVTMSTVGYGDI   +  GKI+V +FIL++ A FASFIPE+AE LF+GS+Y G Y+     +HI+VCG+  ++S+ +F+ DF +EDR  S ++V+FIN++EPD E+++LLK+ F + K+ +GTVMDQVDL R  +  ADAC ILA+ NC +P DEDA NIMR IS KN+     V+IQLLQ+ENK+YL NIPTWNK  GD ++CYSE+EL ILA+SCL+PG+ST ++N+FS+RSE +CK+   S  SW+NDY+ G+ +E+Y++ LS S    ++ +LV F ++ LNLLLIA+EVK  +   K + +NP +       +VG+FIC+S++++    +YC+ CH    + T L+V         ++   I+++ S  E++  T   +     +   +D+     +K  +F  C  +   +++I +  +      HIILCIF+DN + SIG++NF++PLRS     + LK
Sbjct:   76 RPYVNQLISTQFLIGRIVASIATVAALLSTVLYLYEIICLPLKLEKC--YPLTNPIFCSDLACNFVFLIYFLLRFFTSTEKLAFWLGFHTVIDCFTIPQILTALVLDQEWIGLRFIRVLSLIRVFEVIQCFNVVKSGTSIRVIQLITYFASILIVGAGFFHLLENSGEITSGSFYNNSQPIGYGDSLYFIIVTMSTVGYGDIFAKTMCGKIFVVLFILLALATFASFIPELAEFLFAGSQYLGFYIKIAGRRHIIVCGHINYASVSTFLTDFLHEDRSSSDVDVIFINKKEPDIEMKSLLKIYFTQVKYFQGTVMDQVDLHRVQMSNADACLILADQNCSDPNDEDAGNIMRAISFKNYCYRCPVIIQLLQFENKTYLQNIPTWNKRNGDQIICYSEIELGILAQSCLVPGFSTLLTNIFSVRSEKECKQ-NPSNESWLNDYMRGVTMEIYSAKLSRSFNEFSYKELVEFCFKNLNLLLIAIEVKDSVSKKKMLLMNPLNCKRIIPGSVGFFICDSYRDALNANIYCSRCHATLRDLTNLKVCGCKGSPGDYELTVISRLKS-EEEVSLTKCDVENDFKEMEFIDEKCCSYKKNGNFYTCSPQKLMKNVISSEHQIENLRGHIILCIFSDNRTSSIGIRNFLMPLRSVTISENELK 727

HSP 2 Score: 80.4925 bits (197), Expect = 5.546e-15
Identity = 58/211 (27.49%), Postives = 106/211 (50.24%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLS-VLQVENCHVCVIMSARVSKRNAANL--DFHLVDKEIILGTL-------------------------------------NVXXXXXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG 2677
            +L+ ++I ++++F+ +EW  +  FP +  + F+ I+ + ++ ++ ++ C  CVI++   +K N A+L  D ++VDKEII+  L                                     N       +  +   G   ++P   +I+KL +E+NVQ+LD  +++  N P +L + FA G AFTT MLD L+S AY+N +   ++  LI G
Sbjct:  725 ELKELVIIADKDFIEKEWSEICGFPKIK-VVFHQISIRRIAHLISIDTCSRCVILN---NKTNIADLQNDAYMVDKEIIIANLFFQAESKRRIMKNNSKIEMAKSISIKAAGGETQIERTNQSKSEGNETFQVSKGSETQVP---IISKLAIESNVQYLDVREDNVLNIPNYLRKPFAFGCAFTTSMLDSLMSTAYYNQNAIYIMEMLING 928

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Match: SMESG000050831.1 (SMESG000050831.1)

HSP 1 Score: 449.129 bits (1154), Expect = 1.121e-149
Identity = 245/687 (35.66%), Postives = 392/687 (57.06%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVK--MRNGKTVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCH------------------------------------------GANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNP--LEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRL 2169
            W+ + ISGQN TGK +V + C+ +  ++  Y+YE + +    E C + +  +    +DL     F  Y+ +RFLA+ +K+ FW  +YS VDL TIP  FV +YL   W+GLRF+RA+ LM + D+L +L V+KS++  RL  L T F+ + I  SG  H++E++G   ++    ++NFL F    YF IVT+STVGYGDI   +  GK+ +  FIL   A+FA+ IPE+ EI+ S ++Y   +  +++ +HI++CG+  + S+ +F+ADF ++DR    + +V +N   P+ EL+N+LK  F+  +F +G+ M+  DL R  +  ADAC +LAN    +P  EDAANIMRVIS+KNF   ++V++QL+QY NK+YL NIP+W+  +GD  VC +E++L  +A+SCL PG+ST ++NLF++RS      F+   N  +W+N Y+ G G+E+Y+   S +  G TF + V  S++YL LLLIA+E K  +    ++ INP +         G+FI  S  ES+R   +C  CH                                            +E + +++ + + +  N+    +    Q SFR  R  F   +  + +    F  C  +  ++ L+ +   L+   FSNHI++C+FA+++S  IGL NF++PLR+    +S L
Sbjct:   96 WSGEIISGQNLTGKTLVSLVCILSIGSIAIYLYELSVYDGLTEVC-VKWNRSLTQQLDLAFNIIFLVYFFLRFLASNDKLCFWLELYSFVDLYTIPPSFVILYLGRYWIGLRFVRAMRLMTLSDVLGFLNVIKSSSSIRLCHLFTTFVSLVITASGFIHLVESSGGPVIADNGQNRNFLDF---TYFIIVTISTVGYGDIVCRTPTGKLMMMFFILGGLALFANSIPEMIEIIGSRNRYRNPFRKQKDKQHIILCGHITYDSVSNFLADFLHKDREDVDVKIVILNNFPPELELKNVLKRYFIHVEFYQGSGMNSNDLSRIQLQNADACLVLANKYSPDPDAEDAANIMRVISIKNFCPRIKVIVQLMQYHNKAYLLNIPSWDWKRGDDAVCLAELKLGFIAQSCLAPGFSTLLANLFTMRS------FKNDANLPNWLNTYLEGAGMEMYSEYFSPAFHGCTFAEAVAMSFKYLKLLLIAIETKSTVNEENSIAINPKNDIKIEPGMQGFFIAQSADESKRAFFFCRKCHLNRHYKYIKQCSCAAHKQFQNTLHKLRKFETTKSRHSKLESKKGDESSKVKLRRNRNIRPNERKRPHNIRNQKSFRGLR--FNEQISRRFDTTGMFHWCPERPIEDVLLNDSDQLKMCVFSNHIVVCVFAESNSALIGLCNFVMPLRASNFHYSEL 770

HSP 2 Score: 102.449 bits (254), Expect = 1.121e-149
Identity = 97/324 (29.94%), Postives = 157/324 (48.46%), Query Frame = 2

Query: 2162 ADLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEIP---------------------------NRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLI-AGEIHCFENINDEE--------STNMANNNVKCQIRIFNLFDDKFQSCFANTN-RCLYKNLFTYAFXXXXXXXXXXXXXX--------ETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPLS 2998
            ++L  I+   N E+L REW+SLA FP L  +S +++++ +L  + V    +CVI+S   SK N +  D  LVDKE IL +LNV+++       K       +P                           +  +IT+L +++NVQFLDQ+DED P   +F+++ FACG AF   +LD L+S AYFN +   +I  LI  G     E +  E         + +   N  +C++ I  +  +     F + N  C Y +LF  A + + +L +GLY+++             + ++SKK+ ++TNP     +   D V  LQ  S
Sbjct:  768 SELSYIVFIGNLEYLKREWKSLANFPCLSILSGSSLSRTNLRAVNVNMSKMCVILS---SKSNNSMDDAFLVDKEAILCSLNVQAMSFDIDSFKMENFPELLPQISKSVSYSSFGMEKDMTDDKISKSGADIKMITELAIDSNVQFLDQDDEDSPETELFMTQPFACGRAFAVSVLDSLMSTAYFNENALTLIRTLITGGATPDLEQVLAEGCGIQGAYLTPDTLGNRDRCRVTIIQVTQNPLAEIFISKNGGCNYGHLFLEALERFGILCIGLYRLINLDNLVNDNAGMMLNTNSKKRYVITNPPDFLQIHYSDMVYCLQQFS 1088

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Match: SMESG000076792.1 (SMESG000076792.1)

HSP 1 Score: 375.941 bits (964), Expect = 3.628e-129
Identity = 231/688 (33.58%), Postives = 357/688 (51.89%), Query Frame = 1

Query:  253 WTSKFISGQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGN--SWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK----TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGA-------------------------------NEGTPL----RVDKFKCVCINKVASL-NEKIRQTSFRLSRQQFQYAVLDKAEKEID----FLKCDYKDFKESLI--KNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            W  + ISGQN TG++++ I    +  ++  Y  E +      +   I +  ++    DL     F  ++ +R++AA +K  FW  +YSLVD+LT+P  F+   L+  W+GLRF RA+ L+   D+L +L +LKS++K RL  L T+F  + +  +G  H++E TGD     E  +K   T+ D  YF I TMSTVGYGDI   ++ GK+ +  FIL   AIFA+ IPEI EI+ + ++Y G +  +   +HI++CG+  F                         +   P  E              I   V  +    R  ++ ADAC IL +    +P  EDAANIMRVIS+KN+  +++V++QL+QY NK+YL NIP+W+  +GD VVC +E++L  +A+SCL PG+ST ++NLF +RS      F+K  +   W+N Y+ G  LE+YT  LS S  G+TF + V   +  LNLLLIAVEVK  N +    ++ INP         T G+FI  S  +++R   YC  CH +                               N G  L       K + V  N+      +  ++ S  L+         +++++  D    F  C  ++F+ +++  K+ L    FSNHI++CIFAD +SP IGL++F++PLRS    ++ L+
Sbjct:  125 WAGEIISGQNGTGRVLISIVSALSLGSLIIYFIEISQLQGVTDELCIKWSESYTQQFDLAFNIVFLIFFCLRWIAATDKFWFWIEIYSLVDVLTVPPAFMTFVLNRYWVGLRFTRALRLISFTDVLVFLNILKSSSKIRLCHLVTLFTSLVLTSAGFIHLIELTGDI---PEQTNKQNKTYFDYTYFMIATMSTVGYGDIVCKTWQGKLMMIFFILGGLAIFANSIPEIIEIIGNRNRYGGIFKKEIGKQHIILCGHITFQRTNC--------------------DSGHPSTEYS------------IAKCVEKKFKPARVQLEYADACLILCDKYSMDPDAEDAANIMRVISIKNYCPTIKVIVQLMQYHNKAYLMNIPSWDWRRGDDVVCVAELKLGFIAQSCLAPGFSTLLANLFVMRS------FKKYHHLPEWVNQYVEGASLEMYTEYLSPSFHGLTFTEAVCVCFTKLNLLLIAVEVKSNNRRNHSSSIAINPKPDITIEPGTQGFFIAESADDAKRAFYYCMACHMSCKSVKPCNCQSSQHFQDTLYNIVSCSWQMFNNNGKSLIERNSFSKPETVIRNRRKRFGGQSAKRRSQALNDTIHHIKFNEQSQRRFDSTGMFHWCSNREFESAILTNKDDLSSTVFSNHIVVCIFADANSPLIGLRSFVMPLRSSNYHYNELR 771

HSP 2 Score: 107.457 bits (267), Expect = 3.628e-129
Identity = 86/301 (28.57%), Postives = 144/301 (47.84%), Query Frame = 2

Query: 2165 DLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVXXXXXXXXXXXXXXXXXEIPNRF-----------LITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAGEIHCFENINDEESTNMAN---------NNVKCQIRIFNLFDDKFQSCFANTNRCLYKNLFTYAFXXXX----XXXXXXXXXXETTQNILSSSKKKVILTNPDGEFSVSCYDSVLGLQPL 2995
            +LR II    +++L REW+SL  FP +  ++ + +N+  L ++ +  C + VI+S   S      +D +L DKE IL +LN+K++       +    S    N             +IT+L V+++VQ+LDQ+DED P+  +FL++ FACG AF   +LD L+S AYFN +   +I  ++ G           E + +           N  +C++    L +  +   F N     Y +LF   FK Y      L   +   +E     +S++K + ++TNP  E  +   D V  L+P 
Sbjct:  769 ELRQIIFVGPQDYLRREWKSLMNFPKIFVLNGSPLNRSKLRMININLCEMTVILSTNHSN---GLVDAYLADKEAILCSLNIKAMKFTDDNLQSKDLSEIFKNLSTSASHQNSIIPMITELSVDSSVQYLDQDDEDNPDTELFLTQPFACGRAFAVSVLDSLMSTAYFNENALTLIRTMVTGGATLELEELLSEGSGIQGAYLTPETVANRDRCRVETMRLENSPYSELFGNEKT--YGSLFMKCFKEYGILCFGLYRLIIDNMEDCSYSISTNKNRFVVTNPSPETPLMNQDWVFCLRPF 1064

[Close]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Match: SMESG000078105.1 (SMESG000078105.1)

HSP 1 Score: 372.089 bits (954), Expect = 5.069e-119
Identity = 216/634 (34.07%), Postives = 359/634 (56.62%), Query Frame = 1

Query:  274 GQNTTGKIIVFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFTCYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRAIWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGDTWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFILVSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSFMADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQVDLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQLLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISNLFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLVLFSYEYLNLLLIAVEVKMRNGK-TVFINPASQSYTTKETVGYFICNSFKESQRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQFQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADNDSPSIGLKNFIIPLRSKKTRHSRLK 2172
            GQ T    I  +  V    +   Y++    + + +E C  + E   L  I L    FF   ++I F   ++ +EFW  +Y+++++ T+P+ F+ IYL   ++G  FLR IW+ ++PD++Q L +L+  +  RL  L ++F+C+W+ G+G+ ++ ENTGD W + + + K  +++G   YF +VTMSTVGYGDI P +  G+I++ +F+L++ AIFAS+IPE+ +IL S S Y  ++ P    KH +VCG+ E   I+SF++ F++E+R    I ++FI+   P   L+ L+K  + + ++++GT M   DLKR  ++ AD C ++   NC+N   ED ANIMRVIS+K    + RV+IQL Q++NK +L NIP W    GD V+C++E++L ILA+SCL  G+ST I + F+I S       +   N WI  Y  G    +Y    S    G TF + V   Y+   +++I +EV    G+ T+ + P  +   TK+   Y I  +      +++YC  CH +++ + L + K  C  I   ++++ KI      L+  +    +L+K   +  F     + F  S +K   +   F +HI+L +F+  +S S GL NF+ PLR KK  + ++K
Sbjct:   80 GQGTFYGTITLLNVVLNLFSFFIYVFNTNEYYI-LENCCPWNEN-LLEIIQLVLSIFFLISFLIDFSMQKDHLEFWKDLYAIINIFTVPNTFIGIYLQRNYVGTFFLRFIWVYKIPDVIQQLDLLEVKSVIRLWHLGSIFMCIWVCGAGLFYLFENTGDIWHNYKNSQK--ISYGACFYFILVTMSTVGYGDIYPKTDSGRIFLCLFLLIALAIFASYIPEMWDILKSRSIYDKTFRPVYNKKHNIVCGSLEDQEIESFLSTFYHENRNSKNIRIIFISLNRPKLYLKGLMK-RYPQVEYVEGTEMKSEDLKRIRVEIADCCLVITKRNCENEDAEDKANIMRVISIKECCPNQRVIIQLHQFQNKIHLLNIPNWCPLIGDEVICFNEIKLGILARSCLCAGFSTAICHAFTILSPKHI--IKNENNPWIEQYKRGFSASIYRERFSQFFYGRTFLETVHICYDRFKIIVIGLEVIDSYGESTIKLYPNPKHVITKQCWAYCISENQILPYNMSIYCKRCH-SDKNSNLYLKKCYCEIITINSNMSVKIPLKQSLLAHNKEMEKILNK-NLDNKFEITSRRSFYHSFVK--YDKTLF-DHIVLLVFSHENSKSAGLINFVKPLRIKKDDYVKIK 701

HSP 2 Score: 77.411 bits (189), Expect = 5.069e-119
Identity = 51/178 (28.65%), Postives = 92/178 (51.69%), Query Frame = 2

Query: 2147 KKLDTADLRPIIIASNEEFLHREWRSLACFPNLHPISFNNINKKSLSVLQVENCHVCVIMSARVSKRNAANLDFHLVDKEIILGTLNVX-XXXXXXXXXXXXXXXXEIPNRFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLSIAYFNPDVNKVITHLIAG 2677
            KK D   ++PII+  N  +L +EW++++ FP ++ +  +  + + L + QV     CV+++A     N    D +LVDKE+ILGTLN+   +   K+       S    N  +IT + ++ N+ FL     D      + +++FA G A+   +L+ LLS  Y++ +   ++   I G
Sbjct:  693 KKDDYVKIKPIILVGNGVYLEKEWKTISIFPEIYVVVGSCFDLEVLDLAQVNRARTCVLINAP-KPFNHKVEDPYLVDKEVILGTLNLLNYLKYNKVSLSESDFSSSSVNTKIITDVSIDTNMHFLYPNSLDSSQNGAYFTKVFASGHAYCNSILNSLLSSTYYDWNTINLLRLFIEG 869

The following BLAST results are available for this feature:

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Yeast
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNMA1	4.983e-142	36.01	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.369e-142	36.08	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.738e-142	36.08	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.738e-142	36.01	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.834e-142	36.08	potassium calcium-activated channel subfamily M al...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slo-1	1.439e-151	38.37	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	3.563e-151	38.09	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	7.613e-139	42.46	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	1.305e-138	41.50	Calcium-activated potassium channel slo-1 [Source...	[more]
slo-1	2.049e-138	41.50	Calcium-activated potassium channel slo-1 [Source...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slo	6.790e-149	43.42	gene:FBgn0003429 transcript:FBtr0301582	[more]
slo	3.312e-148	43.96	gene:FBgn0003429 transcript:FBtr0330286	[more]
slo	3.626e-148	44.17	gene:FBgn0003429 transcript:FBtr0100622	[more]
slo	7.925e-148	44.55	gene:FBgn0003429 transcript:FBtr0100624	[more]
slo	1.855e-147	43.34	gene:FBgn0003429 transcript:FBtr0334294	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnma1a	1.367e-143	36.32	potassium large conductance calcium-activated chan...	[more]
kcnma1a	3.932e-143	36.24	potassium large conductance calcium-activated chan...	[more]
kcnma1a	6.499e-138	36.24	potassium large conductance calcium-activated chan...	[more]
CABZ01092907.1	7.762e-121	39.83	potassium large conductance calcium-activated chan...	[more]
si:dkey-21e5.1	7.208e-31	27.27	si:dkey-21e5.1 [Source:ZFIN;Acc:ZDB-GENE-141210-6]	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
KCNMA1	6.907e-141	35.74	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	3.833e-140	35.29	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	1.042e-138	34.80	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	2.923e-138	34.49	potassium calcium-activated channel subfamily M al...	[more]
KCNMA1	5.054e-138	35.74	potassium calcium-activated channel subfamily M al...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Kcnma1	3.610e-142	36.08	potassium large conductance calcium-activated chan...	[more]
Kcnma1	3.890e-142	36.08	potassium large conductance calcium-activated chan...	[more]
Kcnma1	4.829e-142	36.08	potassium large conductance calcium-activated chan...	[more]
Kcnma1	4.993e-142	36.08	potassium large conductance calcium-activated chan...	[more]
Kcnma1	7.023e-142	36.07	potassium large conductance calcium-activated chan...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q03720\|SLO_DROME	6.346e-146	44.17	Calcium-activated potassium channel slowpoke OS=Dr...	[more]
sp\|Q8AYS8\|KCMA1_CHICK	2.612e-143	36.69	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|Q9BG98\|KCMA1_RABIT	5.230e-141	35.93	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|Q28204\|KCMA1_BOVIN	5.452e-141	35.93	Calcium-activated potassium channel subunit alpha-...	[more]
sp\|O18866\|KCMA1_PIG	5.876e-141	35.93	Calcium-activated potassium channel subunit alpha-...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A023VZW9	1.536e-161	40.23	SLO-1 2 OS=Trichuris muris OX=70415 PE=2 SV=1	[more]
A0A085MB25	7.981e-161	40.29	Uncharacterized protein OS=Trichuris suis OX=68888...	[more]
A0A1I8J2U5	3.313e-160	37.37	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A061QHQ8	5.969e-160	37.80	Putative calcium-activated potassium channel, slow...	[more]
A0A0V1EKP6	2.160e-158	39.66	Calcium-activated potassium channel slo-1 OS=Trich...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnma1a	4.097e-140	36.06	potassium large conductance calcium-activated chan...	[more]
ENSAMXT00000050702.1	4.249e-138	36.54	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000044980.1	6.327e-137	35.55	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000050440.1	1.207e-136	35.25	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000051878.1	1.099e-127	39.04	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000006399.1	1.995e-97	39.43	pep scaffold:Pmarinus_7.0:GL477091:41003:110164:-1...	[more]
ENSPMAT00000006404.1	2.266e-97	38.80	pep scaffold:Pmarinus_7.0:GL477091:42221:110230:-1...	[more]
ENSPMAT00000007042.1	1.345e-57	42.33	pep scaffold:Pmarinus_7.0:GL486096:7796:16492:-1 g...	[more]
KCNT1	1.688e-21	27.12	potassium sodium-activated channel subfamily T mem...	[more]
ENSPMAT00000001869.1	3.174e-14	26.27	pep scaffold:Pmarinus_7.0:GL480351:152:3521:-1 gen...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO32743	2.608e-27	24.60	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46156	8.798e-15	25.22	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAK6	1.181e-12	31.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31311	1.308e-12	23.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
SHAKR12	9.162e-12	27.71	Potassium channel; Predicted protein [Source:UniP...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kcnma1a	4.480e-143	36.34	calcium-activated potassium channel subunit alpha-...	[more]
ENSORLT00000011055.2	3.037e-142	36.24	potassium calcium-activated channel subfamily M al...	[more]
kcnma1a	1.210e-140	35.29	calcium-activated potassium channel subunit alpha-...	[more]
kcnma1a	3.193e-138	36.42	calcium-activated potassium channel subunit alpha-...	[more]
kcnma1a	4.709e-127	33.93	calcium-activated potassium channel subunit alpha-...	[more]

BLAST of Calcium-activated potassium channel slo-1, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014623.1	1.656e-170	98.61	SMESG000014623.1	[more]
SMESG000044594.1	2.956e-177	41.77	SMESG000044594.1	[more]
SMESG000050831.1	1.121e-149	35.66	SMESG000050831.1	[more]
SMESG000076792.1	3.628e-129	33.58	SMESG000076792.1	[more]
SMESG000078105.1	5.069e-119	34.07	SMESG000078105.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence
protein sequence

transcript sequence

>SMED30001493 ID=SMED30001493|Name=Calcium-activated potassium channel slo-1, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=3071bp
ATCAAAATTAATATGCCAAAATGTTCTGAAAAGAAATGGTATGTGTTTCT
TTTAACAAATGTTATTATAATATTTTCCGGCTTATTCTTGCTATTGCTAT
GGAAATTGATAAAATTTATATACGGAAAAATTTACAAAAAATTGTCACCA
AGAAATTCTAGCCAGGGGAGCTATAAAGCTGGAGAGTTTTCAGGAGGAAA
TAATTCCGGAAGAATCAACGAAGAAAATCAGAATATTCAAATAATTCGAG
TTTGGACATCGAAATTCATTTCCGGTCAAAACACAACCGGGAAAATCATC
GTGTTCATCGCTTGCGTGTGCACCTTCATTACCGTCGGTGACTACATATA
TGAGGCCACGTATTTCCCCATGCAAATTGAAAGGTGCGGGATATATTATG
AAGGAGCCTTCTTACTTGCGATTGACCTTTTCTGTTACTCGTTCTTTACC
TGCTATTATATAATTCGCTTTCTAGCAGCTGAAAATAAAATCGAGTTCTG
GTTTGGGGTCTATTCTTTGGTGGATTTGTTAACAATTCCTAGCTTTTTCG
TGGAGATCTATTTGGATCATCTTTGGATGGGATTGCGGTTTTTAAGAGCA
ATTTGGTTGATGCAAGTCCCGGATTTATTACAATATCTCGGAGTGCTGAA
ATCAGCTACAAAGTTCAGGTTAGGGCAATTGAGTACAATGTTTATTTGCA
TGTGGATTGTGGGATCTGGCATGACGCATATGTTGGAAAATACTGGAGAC
ACCTGGCTTTCAGCGGAAGTAAATGACAAGAATTTCCTCACATTTGGCGA
TAGTATGTATTTCACAATTGTAACTATGTCAACGGTCGGCTACGGAGACA
TTAGCCCACATTCGTTTTTAGGAAAAATATGGGTTGCGATTTTTATTTTG
GTTTCTTTCGCCATTTTTGCTAGTTTCATCCCGGAAATCGCGGAAATTTT
GTTTTCTGGATCTAAATATACCGGAAGTTACGTTCCTAAAGAAGAATATA
AACATATTGTCGTTTGCGGGAATTTTGAGTTTTCATCTATTCAGTCTTTC
ATGGCAGATTTTTTTAATGAAGACAGACCAATTTCGAAGATAAATGTGGT
CTTCATCAACCAAGAAGAACCAGATTTTGAATTACGGAATCTTCTGAAAA
TGAACTTTATGAGATCAAAATTTATTAAGGGAACCGTAATGGACCAGGTG
GATTTGAAGCGAGCGTCGATTGACGAGGCGGATGCTTGTTTCATTCTGGC
GAATCATAATTGCAAAAATCCCAAAGACGAAGACGCCGCAAATATCATGA
GAGTGATCTCGTTGAAGAATTTCTCGTCAAGTGTTCGAGTTCTTATTCAA
TTGTTACAATATGAAAACAAATCCTATTTGACGAACATTCCCACATGGAA
TAAGGATAAAGGCGACACAGTTGTTTGCTACAGCGAGATGGAATTAAGAA
TTCTCGCAAAAAGCTGCTTGATTCCCGGATACTCGACGTTTATTAGCAAT
TTATTTTCCATCCGCTCAGAAGCTCAATGTAAAGAATTCCGCAAATCGGG
CAATTCTTGGATAAATGATTACATAAATGGAATGGGACTCGAACTTTACA
CCAGTAACTTATCTCTTTCTTTGATTGGGATGACCTTTTATGATTTGGTA
CTCTTCTCTTATGAATATCTCAACCTTTTACTAATCGCAGTGGAGGTGAA
AATGAGGAATGGCAAAACGGTATTTATAAATCCGGCATCACAAAGTTACA
CAACAAAAGAAACGGTTGGTTACTTTATATGTAATTCTTTTAAAGAATCT
CAAAGAGTTGCTTTGTATTGTAATGTTTGCCATGGTGCAAATGAGGGAAC
ACCTTTAAGGGTGGATAAGTTCAAATGCGTTTGTATTAACAAAGTAGCCT
CACTTAATGAAAAGATTAGACAAACCAGCTTTCGACTGAGTCGACAACAG
TTCCAGTACGCCGTTTTAGATAAAGCAGAAAAAGAAATCGACTTCCTTAA
GTGTGACTATAAGGATTTTAAGGAGAGTCTGATAAAGAATCCCCTGGAAC
CGATTAAGTTTTCTAATCATATAATTCTGTGCATTTTTGCTGACAATGAT
TCCCCGTCGATCGGATTGAAGAACTTCATAATTCCTTTGCGGTCGAAAAA
AACTCGACACAGCCGACTTAAGACCGATTATTATAGCGAGCAATGAGGAA
TTTCTCCACAGAGAATGGAGATCTTTAGCGTGTTTTCCAAATCTCCATCC
GATTTCATTCAATAACATCAATAAGAAGTCTCTAAGTGTTCTTCAAGTGG
AGAACTGCCACGTTTGCGTGATTATGAGTGCACGAGTCAGCAAACGGAAC
GCAGCGAATCTTGATTTCCATCTCGTCGACAAAGAGATCATTTTGGGCAC
TCTCAATGTCAAGTCTATTTTCAAGAAAAAACTTCAAAAAAAATTCATCG
GAAAATCCGGAGAAATCCCAAATCGATTTCTAATCACAAAATTATTAGTG
GAAAACAATGTCCAGTTTCTAGATCAAGAAGACGAAGACGAACCGAACTG
TCCGGTATTTCTCTCGGAAATATTTGCATGCGGTAGCGCGTTCACCACGA
AAATGCTGGATTGTCTACTGAGCATCGCCTATTTTAATCCGGACGTCAAC
AAAGTCATCACGCATTTGATTGCCGGGGAGATCCATTGCTTCGAAAACAT
CAACGACGAAGAAAGTACTAATATGGCAAACAACAACGTCAAATGTCAAA
TTCGGATTTTTAATTTGTTTGACGACAAATTCCAGTCATGTTTTGCCAAC
ACGAATCGTTGCTTGTATAAGAACCTCTTTACGTACGCCTTCAAGCATTA
CCACTTATTGCTATTGGGACTTTATAAGGTCGTTGAAACCACACAAAATA
TTCTTTCTTCCAGTAAAAAAAAGGTTATTCTGACAAACCCCGATGGTGAA
TTTTCCGTCAGCTGTTACGATTCGGTTCTCGGGTTACAGCCGCTAAGCCA
GTGTGACTTTACTATTACGAATTGACAGATTTATTATACATTTCATCAAG
AGTTACTTTTATCCTCCCCGG

protein sequence of SMED30001493-orf-1

>SMED30001493-orf-1 ID=SMED30001493-orf-1|Name=SMED30001493-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=234bp
MSARVSKRNAANLDFHLVDKEIILGTLNVKSIFKKKLQKKFIGKSGEIPN
RFLITKLLVENNVQFLDQEDEDEPNCPVFLSEIFACGSAFTTKMLDCLLS
IAYFNPDVNKVITHLIAGEIHCFENINDEESTNMANNNVKCQIRIFNLFD
DKFQSCFANTNRCLYKNLFTYAFKHYHLLLLGLYKVVETTQNILSSSKKK
VILTNPDGEFSVSCYDSVLGLQPLSQCDFTITN*

protein sequence of SMED30001493-orf-2

>SMED30001493-orf-2 ID=SMED30001493-orf-2|Name=SMED30001493-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=732bp
IKINMPKCSEKKWYVFLLTNVIIIFSGLFLLLLWKLIKFIYGKIYKKLSP
RNSSQGSYKAGEFSGGNNSGRINEENQNIQIIRVWTSKFISGQNTTGKII
VFIACVCTFITVGDYIYEATYFPMQIERCGIYYEGAFLLAIDLFCYSFFT
CYYIIRFLAAENKIEFWFGVYSLVDLLTIPSFFVEIYLDHLWMGLRFLRA
IWLMQVPDLLQYLGVLKSATKFRLGQLSTMFICMWIVGSGMTHMLENTGD
TWLSAEVNDKNFLTFGDSMYFTIVTMSTVGYGDISPHSFLGKIWVAIFIL
VSFAIFASFIPEIAEILFSGSKYTGSYVPKEEYKHIVVCGNFEFSSIQSF
MADFFNEDRPISKINVVFINQEEPDFELRNLLKMNFMRSKFIKGTVMDQV
DLKRASIDEADACFILANHNCKNPKDEDAANIMRVISLKNFSSSVRVLIQ
LLQYENKSYLTNIPTWNKDKGDTVVCYSEMELRILAKSCLIPGYSTFISN
LFSIRSEAQCKEFRKSGNSWINDYINGMGLELYTSNLSLSLIGMTFYDLV
LFSYEYLNLLLIAVEVKMRNGKTVFINPASQSYTTKETVGYFICNSFKES
QRVALYCNVCHGANEGTPLRVDKFKCVCINKVASLNEKIRQTSFRLSRQQ
FQYAVLDKAEKEIDFLKCDYKDFKESLIKNPLEPIKFSNHIILCIFADND
SPSIGLKNFIIPLRSKKTRHSRLKTDYYSEQ*

protein sequence of SMED30001493-orf-3

>SMED30001493-orf-3 ID=SMED30001493-orf-3|Name=SMED30001493-orf-3|organism=Schmidtea mediterranea sexual|type=polypeptide|length=101bp
MLLNEIGWRFGKHAKDLHSLWRNSSLLAIIIGLKSAVSSFFRPQRNYEVL
QSDRRGIIVSKNAQNYMIRKLNRFQGILYQTLLKILIVTLKEVDFFFCFI
*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0034220	ion transmembrane transport
GO:0006813	potassium ion transport
GO:0055085	transmembrane transport
GO:0006811	ion transport
GO:0006810	transport
GO:0034765	regulation of ion transmembrane transport
GO:0040011	locomotion
GO:0042493	response to drug
GO:0043050	pharyngeal pumping
GO:0045214	sarcomere organization
GO:0046928	regulation of neurotransmitter secretion
GO:0048149	behavioral response to ethanol
GO:0050804	modulation of synaptic transmission
GO:0071805	potassium ion transmembrane transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR027359	Volt_channel_dom_sf
IPR036291	NAD(P)-bd_dom_sf
IPR028325	VG_K_chnl
IPR003929	K_chnl_BK_asu
IPR016040	NAD(P)-bd_dom
IPR005821	Ion_trans_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005249	voltage-gated potassium channel activity
GO:0015269	calcium-activated potassium channel activity
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0060072	large conductance calcium-activated potassium channel activity

Vocabulary: **cellular component**
Term	Definition
GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031430	M band
GO:0045202	synapse
GO:0055120	striated muscle dense body

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 656..676
None	No IPR available	PRINTS	PR01449	BKCHANNELA	coord: 365..385 score: 34.52 coord: 487..502 score: 58.07 coord: 408..428 score: 57.14 coord: 441..454 score: 35.71
None	No IPR available	PRINTS	PR00169	KCHANNEL	coord: 166..186 score: 25.38 coord: 262..284 score: 45.5 coord: 140..163 score: 29.98
None	No IPR available	GENE3D	G3DSA:1.10.287.70		coord: 223..322 e-value: 2.8E-18 score: 67.6
None	No IPR available	GENE3D	G3DSA:3.40.50.720		coord: 329..464 e-value: 1.0E-15 score: 59.7
None	No IPR available	PANTHER	PTHR10027:SF33	POTASSIUM LARGE CONDUCTANCE CALCIUM-ACTIVATED CHANNEL, SUBFAMILY M, ALPHA MEMBER 1A	coord: 74..730
None	No IPR available	PANTHER	PTHR10027	CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN	coord: 74..730
None	No IPR available	SUPERFAMILY	SSF81324	Voltage-gated potassium channels	coord: 101..317
None	No IPR available	TMHMM	TMhelix		coord: 166..188
None	No IPR available	TMHMM	TMhelix		coord: 262..281
None	No IPR available	TMHMM	TMhelix		coord: 15..37
None	No IPR available	TMHMM	TMhelix		coord: 100..122
None	No IPR available	TMHMM	TMhelix		coord: 137..159
None	No IPR available	TMHMM	TMhelix		coord: 288..310
IPR003929	Calcium-activated potassium channel BK, alpha subunit	PFAM	PF03493	BK_channel_a	coord: 465..564 e-value: 3.2E-24 score: 85.0
IPR027359	Voltage-dependent channel domain superfamily	GENE3D	G3DSA:1.20.120.350		coord: 83..222 e-value: 4.0E-8 score: 34.8
IPR005821	Ion transport domain	PFAM	PF00520	Ion_trans	coord: 99..315 e-value: 1.9E-14 score: 53.5
IPR036291	NAD(P)-binding domain superfamily	SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	coord: 334..498

Main menu

Calcium-activated potassium channel slo-1, putative

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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