Tudor domain-containing protein 12
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001485 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Match: TDRD12 (tudor domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25044]) HSP 1 Score: 173.711 bits (439), Expect = 7.382e-43 Identity = 188/733 (25.65%), Postives = 323/733 (44.07%), Query Frame = 3
Query: 954 VRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLL--MPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFITATV-WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDIL-IYNAEIILHVD--VSEPSFGNRLNFLRDKYAKLSFLKSRNEPIE----KCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVK---VKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVP 3086
++P L+ + L A LK+A+ ++ +SY P I RG + + I+ + LL + VLQT A + PSR PLA+I+C WKK + E + + S + + + K T +P +GCDV++ TP LL L L + LD+ E + E E + IL K +R S P Q + V W +E +K M D + I + E A+ V+Q + + +E + L+ L+ S ++T+IF + + +V K + + LKM + L ++ +W + + IL ++D+ C +L I +A ++H S FG RL + D F + P E K S + + T + A + R+L R + P L E + + KE K +CP +K FG CK C RH + + D P LP+ G+I+ Y+++ +++F RI + + Y +L +M YF + + + V L + K L RV V ++ + + V+ ID+G +V + LL LP+ +PPQA+E V ++P DN+ ++ + + + + K A + L +G+T+WID + + + + +V D N+ +L + N +HIE+L +L + D P+ EES + P
Sbjct: 412 IKPCLTIDSSPLSAD-LKKALQRNKFPGPSHTESYSWPPIARGCDVVVISHCESNPLLYLLPVLTVLQTGACYKSLPSRN-GPLAVIVCPGWKKAQFIF---ELLGEYSMSSRPLHPVLLTIGLHKEEAKNTKLP--RGCDVIVTTPYSLLRLLACQSLLFLRLCHLI-LDEVEVLFLEANEQMFAILDNFKKNIEVEERESAPHQIVAVGVHWNKHIEHLIKEFMNDPY-IVITAMEEAALYGNVQQVV--HLCLECEKTSSLLQALDFIPSQAQKTLIFTCSVAETEIVCKVVESSSIFCLKMHKEMIF--NLQNVLEQWKKKLSSGSQIILALTDD---CVPLLAITDATCVIHFSFPASPKVFGGRLYCMSDH-----FHAEQGSPAEQGDKKAKSVLLL--TEKDASHAVGVLRYLERADAKVPAELYEFTAGVLEAKEDKKAGRPLCPYLKAFGFCKDKRICPDRHRINPETDLPRKLSSQALPSFGYIKIIPFYILNATNYFGRIVD---------KHMDLYATLNAEMNEYFKDS---NKTTVEKVEKFGLYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEGRTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHHKIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKL---REDAKIPACEESLSQTPP 1106
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Match: TDRD12 (tudor domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25044]) HSP 1 Score: 169.474 bits (428), Expect = 1.844e-41 Identity = 187/738 (25.34%), Postives = 322/738 (43.63%), Query Frame = 3
Query: 954 VRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLL--MPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFITATV-WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDIL-IYNAEIILHVD--VSEPSFGNRLNFLRDKYAKLSFLKSRNEPIE----KCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECK------LPGCVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVK---VKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVP 3086
++P L+ + L A LK+A+ ++ +SY P I RG + + I+ + LL + VLQT A + PSR PLA+I+C WKK + E + + S + + + K T +P +GCDV++ TP LL L L + LD+ E + E E + IL K +R S P Q + V W +E +K M D + I + E A+ V+Q + + +E + L+ L+ S ++T+IF + + +V K + + LKM + L ++ +W + + IL ++D+ C +L I +A ++H S FG RL + D F + P E K S + + T + A + R+L R + P L E + + KE K +CP +K FG C C RH + + D P LP+ G+I+ Y+++ +++F RI + + Y +L +M YF + + + V L + K L RV V ++ + + V+ ID+G +V + LL LP+ +PPQA+E V ++P DN+ ++ + + + + K A + L +G+T+WID + + + + +V D N+ +L + N +HIE+L +L + D P+ EES + P
Sbjct: 412 IKPCLTIDSSPLSAD-LKKALQRNKFPGPSHTESYSWPPIARGCDVVVISHCESNPLLYLLPVLTVLQTGACYKSLPSRN-GPLAVIVCPGWKKAQFIF---ELLGEYSMSSRPLHPVLLTIGLHKEEAKNTKLP--RGCDVIVTTPYSLLRLLACQSLLFLRLCHLI-LDEVEVLFLEANEQMFAILDNFKKNIEVEERESAPHQIVAVGVHWNKHIEHLIKEFMNDPY-IVITAMEEAALYGNVQQVV--HLCLECEKTSSLLQALDFIPSQAQKTLIFTCSVAETEIVCKVVESSSIFCLKMHKEMIF--NLQNVLEQWKKKLSSGSQIILALTDD---CVPLLAITDATCVIHFSFPASPKVFGGRLYCMSD-----HFHAEQGSPAEQGDKKAKSVLLL--TEKDASHAVGVLRYLERADAKVPAELYEFTAGVLEAKEDKKAGRPLCPYLKAFGFCNHFIFRDKRICPDRHRINPETDLPRKLSSQALPSFGYIKIIPFYILNATNYFGRIVD---------KHMDLYATLNAEMNEYFKDS---NKTTVEKVEKFGLYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEGRTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHHKIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKL---REDAKIPACEESLSQTPP 1111
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Match: TDRD12 (tudor domain containing 12 [Source:HGNC Symbol;Acc:HGNC:25044]) HSP 1 Score: 67.781 bits (164), Expect = 5.778e-11 Identity = 48/175 (27.43%), Postives = 87/175 (49.71%), Query Frame = 3
Query: 2571 LAAIKIKDLLERVVVSKMKSNQSGGYVK---VKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVP 3086
L + K L RV V ++ + + V+ ID+G +V + LL LP+ +PPQA+E V ++P DN+ ++ + + + + K A + L +G+T+WID + + + + +V D N+ +L + N +HIE+L +L + D P+ EES + P
Sbjct: 11 LYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEGRTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHHKIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKL---REDAKIPACEESLSQTPP 182
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Match: DDX41 (DEAD-box helicase 41 [Source:HGNC Symbol;Acc:HGNC:18674]) HSP 1 Score: 60.4622 bits (145), Expect = 2.443e-8 Identity = 84/357 (23.53%), Postives = 144/357 (40.34%), Query Frame = 3
Query: 894 WTVQKY-------RTENETTDFNYL----GSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI--ATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYR 1916
WT +Y R E ++ L G PI S+K K A L+ + K IQ IP IL G + + IA GK++ +PV+ K+L S+ P +I+C S + + E + R ++ D R G K M + G +++ TP L+ L Q + L+ LD+A+ +I E ++ I Y +G + +AT+ +++++ K + +I V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G EE + + + +
Sbjct: 146 WTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILR-GLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCR-LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLL-QKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYF------KGQRQTLLFSATM-PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEV-----EYVKEEA----KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKG-VEAVAIHGGKDQEERTKAIEAFREGK 482
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Match: DDX4 (DEAD-box helicase 4 [Source:HGNC Symbol;Acc:HGNC:18700]) HSP 1 Score: 58.151 bits (139), Expect = 1.117e-7 Identity = 46/175 (26.29%), Postives = 84/175 (48.00%), Query Frame = 3
Query: 963 ILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENII 1478
IL+++ L T L ++K L +Q Y IP IL G + +A A GK+ L+P+L + ++ SR P II+ + + V+++ A KF+ R V Y G+ ++ ++QGC++L TP L+ + + E L +++ LD+A+ ++
Sbjct: 138 ILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTC-------VRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGK-EKIGLKQIKYLVLDEADRML 303
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Match: Rm62 (gene:FBgn0003261 transcript:FBtr0301947) HSP 1 Score: 68.5514 bits (166), Expect = 3.608e-11 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 115 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 452
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Match: Rm62 (gene:FBgn0003261 transcript:FBtr0078650) HSP 1 Score: 68.5514 bits (166), Expect = 3.608e-11 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 115 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 452
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Match: Rm62 (gene:FBgn0003261 transcript:FBtr0078649) HSP 1 Score: 68.5514 bits (166), Expect = 3.884e-11 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 118 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 455
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Match: Rm62 (gene:FBgn0003261 transcript:FBtr0078651) HSP 1 Score: 68.5514 bits (166), Expect = 3.884e-11 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 118 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 455
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Match: Rm62 (gene:FBgn0003261 transcript:FBtr0078654) HSP 1 Score: 68.5514 bits (166), Expect = 3.884e-11 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 118 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 455
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Match: tdrd12 (tudor domain containing 12 [Source:ZFIN;Acc:ZDB-GENE-121214-348]) HSP 1 Score: 146.362 bits (368), Expect = 1.441e-34 Identity = 163/701 (23.25%), Postives = 311/701 (44.37%), Query Frame = 3
Query: 1032 KFLL--------IIQSYMIPNILRGFNTLAIA----------PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAE--KFTRFI--------IDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIY--KRTGAIDRGSEPSQFIT-ATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV-SEPS-FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHV----GLLAAIKIKDLLERVVVSKM--KSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKL 3014
KFLL + +SY P + RGF+T+ ++ PP LLM +LQT++ +RT P+A+ILC W+KV + + E K T + +D D+ ++ +I + C +L+ TP LL L+ F L + LD+A+ + ++ + + IL + + A +R + P Q I W++ ++ V+ M ++ + E A+ RV Q++ D D L++ L+ ++T+I ++ ++ VYK ++ A LK + ++ + ++ +W + IL+ +++ L+ + I +A ++H S P FG+RL + + + KLS + + S + + + N+R + R+L R G+ P L + ++ KE+ K +C +K FG C+ C RH + + +D+ LP+ G I L++ + S + RI + K + QM +H + R V G L AI+ ++ RV V ++ K Q V LID+G V+ LLQLP + ++P QA+E + ++P+D + ++ + + + K A + + +G+T+W+D + + + + + + N+ +L N QH++ L
Sbjct: 446 KFLLWRKYSGPNVAESYCWPAVARGFDTVLVSHSGDNPLSYIPP-------LLM-ILQTVSVVSSLAART-GPVAVILCPGWEKVQTVLELLEDSKATHGLHPTSVLLGVDQDEPKKFKI----------------QKNCQLLVTTPFSLLRLLEAQCFLFLRLCHLV-LDEADLLYSQAPDQISIILKHFQQLVCAEERVACPRQIIAVGGRWSAGIDGLVREHMIHP-TVIITVMEEAALYGRVHQRVQLCLDC--DKVSVLLSSLDFQPPKPQKTLIITNSAEETEHVYKAVVNTAVFTLKAHEDAT--DQFDFIIDQWRKDISQGTQVILVTTNDCLKA--LGIRDATCVVHYGFPSTPKLFGSRLFCMSENFRKLSDMDHSEDWTPGAQSVLLL--SEQNVRHVCGVLRYLRRTGALLPPELLQFALGIQQAKEEQKTHRPLCCSLKSFGFCRDSTVCPDRHTINTSLDQTQLPDSGMIMVLPLFIKTASVYCGRI-----------------VRQKEDLYEDLATQMKLHYASERRCAVEVLKGALYAIQEENCYHRVRVLEVPEKGEQLFSSVTACLIDEGRTQEVKSHQLLQLPAQFQDLPGQAVEIILCRVQPVDGEVDWNPKVTRAVSLKIRGKLHQARVVMSLGNTIWVDPMVRMVRVPGLKTFINEYNVHTEILASGFGVSNPQHVDLL 1094
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Match: tdrd12 (tudor domain containing 12 [Source:ZFIN;Acc:ZDB-GENE-121214-348]) HSP 1 Score: 146.362 bits (368), Expect = 1.571e-34 Identity = 163/701 (23.25%), Postives = 311/701 (44.37%), Query Frame = 3
Query: 1032 KFLL--------IIQSYMIPNILRGFNTLAIA----------PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAE--KFTRFI--------IDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIY--KRTGAIDRGSEPSQFIT-ATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV-SEPS-FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHV----GLLAAIKIKDLLERVVVSKM--KSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKL 3014
KFLL + +SY P + RGF+T+ ++ PP LLM +LQT++ +RT P+A+ILC W+KV + + E K T + +D D+ ++ +I + C +L+ TP LL L+ F L + LD+A+ + ++ + + IL + + A +R + P Q I W++ ++ V+ M ++ + E A+ RV Q++ D D L++ L+ ++T+I ++ ++ VYK ++ A LK + ++ + ++ +W + IL+ +++ L+ + I +A ++H S P FG+RL + + + KLS + + S + + + N+R + R+L R G+ P L + ++ KE+ K +C +K FG C+ C RH + + +D+ LP+ G I L++ + S + RI + K + QM +H + R V G L AI+ ++ RV V ++ K Q V LID+G V+ LLQLP + ++P QA+E + ++P+D + ++ + + + K A + + +G+T+W+D + + + + + + N+ +L N QH++ L
Sbjct: 487 KFLLWRKYSGPNVAESYCWPAVARGFDTVLVSHSGDNPLSYIPP-------LLM-ILQTVSVVSSLAART-GPVAVILCPGWEKVQTVLELLEDSKATHGLHPTSVLLGVDQDEPKKFKI----------------QKNCQLLVTTPFSLLRLLEAQCFLFLRLCHLV-LDEADLLYSQAPDQISIILKHFQQLVCAEERVACPRQIIAVGGRWSAGIDGLVREHMIHP-TVIITVMEEAALYGRVHQRVQLCLDC--DKVSVLLSSLDFQPPKPQKTLIITNSAEETEHVYKAVVNTAVFTLKAHEDAT--DQFDFIIDQWRKDISQGTQVILVTTNDCLKA--LGIRDATCVVHYGFPSTPKLFGSRLFCMSENFRKLSDMDHSEDWTPGAQSVLLL--SEQNVRHVCGVLRYLRRTGALLPPELLQFALGIQQAKEEQKTHRPLCCSLKSFGFCRDSTVCPDRHTINTSLDQTQLPDSGMIMVLPLFIKTASVYCGRI-----------------VRQKEDLYEDLATQMKLHYASERRCAVEVLKGALYAIQEENCYHRVRVLEVPEKGEQLFSSVTACLIDEGRTQEVKSHQLLQLPAQFQDLPGQAVEIILCRVQPVDGEVDWNPKVTRAVSLKIRGKLHQARVVMSLGNTIWVDPMVRMVRVPGLKTFINEYNVHTEILASGFGVSNPQHVDLL 1135
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Match: tdrd12 (tudor domain containing 12 [Source:ZFIN;Acc:ZDB-GENE-121214-348]) HSP 1 Score: 144.821 bits (364), Expect = 3.330e-34 Identity = 160/672 (23.81%), Postives = 300/672 (44.64%), Query Frame = 3
Query: 1032 KFLL--------IIQSYMIPNILRGFNTLAIA----------PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAE--KFTRFI--------IDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIY--KRTGAIDRGSEPSQFIT-ATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV-SEPS-FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHV----GLLAAIKIKDLLERVVVSKM--KSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQT 2927
KFLL + +SY P + RGF+T+ ++ PP LLM +LQT++ +RT P+A+ILC W+KV + + E K T + +D D+ ++ +I + C +L+ TP LL L+ F L + LD+A+ + ++ + + IL + + A +R + P Q I W++ ++ V+ M ++ + E A+ RV Q++ D D L++ L+ ++T+I ++ ++ VYK ++ A LK + ++ + ++ +W + IL+ +++ L+ + I +A ++H S P FG+RL + + + KLS + + S + + + N+R + R+L R G+ P L + ++ KE+ K +C +K FG C+ C RH + + +D+ LP+ G I L++ + S + RI + K + QM +H + R V G L AI+ ++ RV V ++ K Q V LID+G V+ LLQLP + ++P QA+E + ++P+D + ++ + + + K A + + +G+T+W+D + + HH T
Sbjct: 167 KFLLWRKYSGPNVAESYCWPAVARGFDTVLVSHSGDNPLSYIPP-------LLM-ILQTVSVVSSLAART-GPVAVILCPGWEKVQTVLELLEDSKATHGLHPTSVLLGVDQDEPKKFKI----------------QKNCQLLVTTPFSLLRLLEAQCFLFLRLCHLV-LDEADLLYSQAPDQISIILKHFQQLVCAEERVACPRQIIAVGGRWSAGIDGLVREHMIHP-TVIITVMEEAALYGRVHQRVQLCLDC--DKVSVLLSSLDFQPPKPQKTLIITNSAEETEHVYKAVVNTAVFTLKAHEDAT--DQFDFIIDQWRKDISQGTQVILVTTNDCLKA--LGIRDATCVVHYGFPSTPKLFGSRLFCMSENFRKLSDMDHSEDWTPGAQSVLLL--SEQNVRHVCGVLRYLRRTGALLPPELLQFALGIQQAKEEQKTHRPLCCSLKSFGFCRDSTVCPDRHTINTSLDQTQLPDSGMIMVLPLFIKTASVYCGRI-----------------VRQKEDLYEDLATQMKLHYASERRCAVEVLKGALYAIQEENCYHRVRVLEVPEKGEQLFSSVTACLIDEGRTQEVKSHQLLQLPAQFQDLPGQAVEIILCRVQPVDGEVDWNPKVTRAVSLKIRGKLHQARVVMSLGNTIWVDPMVRIRHHGAT 786
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Match: ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:NCBI gene;Acc:321948]) HSP 1 Score: 56.225 bits (134), Expect = 3.730e-7 Identity = 40/170 (23.53%), Postives = 78/170 (45.88%), Query Frame = 3
Query: 900 VQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWL 1409
V +YR E E G +PI ++ + L A+ KH+ + IQ+ IP I+ G + + IA GK++ L+P+ + I Q PLA+I+ + + ++ +KF++ + R+V Y G+ + + +G ++++ TP ++ L
Sbjct: 318 VSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLN-ALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHI-LDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLA-------LRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDML 478
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Match: ddx42 (DEAD (Asp-Glu-Ala-Asp) box helicase 42 [Source:ZFIN;Acc:ZDB-GENE-050706-53]) HSP 1 Score: 55.8398 bits (133), Expect = 5.548e-7 Identity = 67/340 (19.71%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVL-QTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENI-----------IAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLEL-AVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI----LIYNAEIILHVDV 2015
IQ +P L G + + IA GK+ + P+L + K+L P P+A+I+C + + ++ ++F K R VA Y G + +G ++++ TP L+ +K+ + L + D+A+ + IA H+ ++ L++ T + ++E + + D + D E I ++ + + +D G L ++LV + +S ++F + + + L+Q+ L ++ G M E N ++ ++ + N+P+L+ +D A R DI + N ++ +D
Sbjct: 281 IQCQGVPIALSGRDAIGIAKTGSGKTAAFIWPILVHIMDQKELEPGE--GPIAVIVCPTRELCQQIHAECKRFG-------KAYGLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATSLQRVTFLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSAT-----------------FRKKIEKLARDILVDPIRVVQGDIGEANEDITQIVEVLQSGQDKWGWLTRRLVEF-----TSAGSVLVFVTKKANCEELATNLIQEG-YSLGLLHGDMDQSERNKVIADFKKK----NLPVLVATDVAARGLDIPSIRTVVNYDVARDIDT 583
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Match: smarcd3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 [Source:Xenbase;Acc:XB-GENE-494884]) HSP 1 Score: 120.939 bits (302), Expect = 8.361e-27 Identity = 170/682 (24.93%), Postives = 273/682 (40.03%), Query Frame = 3
Query: 1050 QSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI----ATKQLSPSRTYNPLAIILCSSWKK---VSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTM--IPVLQGCDVLIITPNCLLSWLK-------QHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFI-TATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPS--FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLH-----RFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARL 3023
+SY P++ +GFNT+ I+P K M + P+L + A L PSR PLA ILCS WKK V EL K TR + P ++ LK+ + + +GC+V++ TP LL +LK + L+E++I L +I E LE L K A R P Q + T T W + S +++ + I +E A + Q++I+ + + L+ L+ T ++ +IF +D++ LV+K M V K S ++++W +L++++E L ++ +A I+H E FG RL Y+ L ++ S+ E + + + L + + H R+L + P L + + + E K +IC IK FG HFF RI E Y+ L K NQ+ + VN V L A++ + RV V K ++ ID G V A LLQLP + +IPPQ+ E V ++PIDN+ + + ++ K A + L IG+T W+D + QR + + + N+ +L + N QHI L L
Sbjct: 146 ESYSWPSVAQGFNTIVISP-DGMKPMNYIPPLLTFLHLASAVYTLLPSRN-GPLAAILCSGWKKAHFVHELLLKYSKHTRPL-------NPMLILV---GLKEEECENLNIRKGCEVIVTTPPSLLRYLKCKGLLLLRLCHLVLDEVDILFLKSGSQVI-EILE-----LFKKSVAAESRECAPQQIVATGTFWHKEMNSLLQYTTEPQVIIT---RMEQAAVYGNVQQVIQL-CLNCEKISVLLRNLDFTPDHAQKVLIFVESDEEAELVHKVSMN--IVHKKRYFSS--------VLQQWKNMLSRGTHIVLVVTNEYLPLLEVT--DATCIIHFSFPENENVFGLRL------YSLLDYIHSKTERVISLEDSFPVARSVLLMTEKHIHHSTDILRYLQHTEATIPPELSDLTQGILQANENRKFDKDICQHIKTFGV-------------------------------------FHFFGRI------VTKEDVYTHLLEDLN-KFYQIPGNQILVQEVN-----VSQLYAVQEGSVYHRVKVFSAKKENGVLNFSLQFIDDGRTDKVRDAQLLQLPSQFEKIPPQSAEFIVCRVQPIDNEAEWDPIVTRTISKAIKGKLHTAKVVLHIGNTYWLDPMVQRSKLSGFAACINELNVRHEILSTGMGVDNPQHISHLEEL 738
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Match: smarcd3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 [Source:Xenbase;Acc:XB-GENE-494884]) HSP 1 Score: 116.316 bits (290), Expect = 2.004e-25 Identity = 169/679 (24.89%), Postives = 280/679 (41.24%), Query Frame = 3
Query: 1050 QSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI----ATKQLSPSRTYNPLAIILCSSWKK---VSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTM--IPVLQGCDVLIITPNCLLSWLK-------QHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFI-TATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPS--FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPLLPNKGHIQF--RLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARL 3023
+SY P++ +GFNT+ I+P K M + P+L + A L PSR PLA ILCS WKK V EL K TR + P ++ LK+ + + +GC+V++ TP LL +LK + L+E++I L +I E LE L K A R P Q + T T W + S +++ + I +E A + Q++I+ + + L+ L+ T ++ +IF +D++ LV+K M V K S ++++W +L++++E L ++ +A I+H E FG RL Y+ L ++ S+ E + + + L + + H S D + + ++ + I P LSD+ + +L + +F +L+++ P HFF RI E Y+ L K NQ+ + VN V L A++ + RV V K ++ ID G V A LLQLP + +IPPQ+ E V ++PIDN+ + + ++ K A + L IG+T W+D + QR + + + N+ +L + N QHI L L
Sbjct: 146 ESYSWPSVAQGFNTIVISP-DGMKPMNYIPPLLTFLHLASAVYTLLPSRN-GPLAAILCSGWKKAHFVHELLLKYSKHTRPL-------NPMLILV---GLKEEECENLNIRKGCEVIVTTPPSLLRYLKCKGLLLLRLCHLVLDEVDILFLKSGSQVI-EILE-----LFKKSVAAESRECAPQQIVATGTFWHKEMNSLLQYTTEPQVIIT---RMEQAAVYGNVQQVIQL-CLNCEKISVLLRNLDFTPDHAQKVLIFVESDEEAELVHKVSMN--IVHKKRYFSS--------VLQQWKNMLSRGTHIVLVVTNEYLPLLEVT--DATCIIHFSFPENENVFGLRL------YSLLDYIHSKTERVISLEDSFPVARSVLLMTEKHIHH-----------------STDILRYLQHTEAT--IPPE------------------LSDLTQGILQANENRKFDKDILHVLDPVHFFGRI------VTKEDVYTHLLEDLN-KFYQIPGNQILVQEVN-----VSQLYAVQEGSVYHRVKVFSAKKENGVLNFSLQFIDDGRTDKVRDAQLLQLPSQFEKIPPQSAEFIVCRVQPIDNEAEWDPIVTRTISKAIKGKLHTAKVVLHIGNTYWLDPMVQRSKLSGFAACINELNVRHEILSTGMGVDNPQHISHLEEL 735
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Match: polg2 (polymerase (DNA directed), gamma 2, accessory subunit [Source:Xenbase;Acc:XB-GENE-1009985]) HSP 1 Score: 63.5438 bits (153), Expect = 2.712e-9 Identity = 75/285 (26.32%), Postives = 131/285 (45.96%), Query Frame = 3
Query: 1008 EAMSKHDTKF----LLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITAT--VWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSI-KRTIIFASTDDDILLVYKYLMQK 1832
E +S++ TK L +Q + IP IL G + +A A GK+ L+P+L + + ++ S+ P AII+ + + ++++ A KF+ RP +V Y G M V +GC++L TP L+ + + E L++L+ LD+A+ ++ + E LI G + + +AT RL S K D + V L V+Q I+E ++ Y+K +E+ +SS +RT+IF +T ++ YL Q+
Sbjct: 192 ETLSRNVTKAGYVKLTPVQKHSIPIILAGRDLMACAQTGSGKTAAFLLPILSHMMNEGITASQFLPLQEPQAIIIAPTRELINQIYLDARKFSY-----GTCVRPVVV--YGGIHPVHAMRDVERGCNILCATPGRLMDIIGR-EKIGLSKLKYLVLDEADRMLDMGFAPVMENLI-GSPGMPAKEERQTLMFSATYPAEIQRLAS--KFLKSDHLFVVVG--LVGGACSDVEQTILEIQE-----YRKRDKLVEILQSSGNERTMIFVNTKKKADVIAGYLCQE 458
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Match: polg2 (polymerase (DNA directed), gamma 2, accessory subunit [Source:Xenbase;Acc:XB-GENE-1009985]) HSP 1 Score: 63.5438 bits (153), Expect = 2.779e-9 Identity = 75/285 (26.32%), Postives = 131/285 (45.96%), Query Frame = 3
Query: 1008 EAMSKHDTKF----LLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITAT--VWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSI-KRTIIFASTDDDILLVYKYLMQK 1832
E +S++ TK L +Q + IP IL G + +A A GK+ L+P+L + + ++ S+ P AII+ + + ++++ A KF+ RP +V Y G M V +GC++L TP L+ + + E L++L+ LD+A+ ++ + E LI G + + +AT RL S K D + V L V+Q I+E ++ Y+K +E+ +SS +RT+IF +T ++ YL Q+
Sbjct: 241 ETLSRNVTKAGYVKLTPVQKHSIPIILAGRDLMACAQTGSGKTAAFLLPILSHMMNEGITASQFLPLQEPQAIIIAPTRELINQIYLDARKFS-----YGTCVRPVVV--YGGIHPVHAMRDVERGCNILCATPGRLMDIIGR-EKIGLSKLKYLVLDEADRMLDMGFAPVMENLI-GSPGMPAKEERQTLMFSATYPAEIQRLAS--KFLKSDHLFVVVG--LVGGACSDVEQTILEIQE-----YRKRDKLVEILQSSGNERTMIFVNTKKKADVIAGYLCQE 507
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Match: polg2 (polymerase (DNA directed), gamma 2, accessory subunit [Source:Xenbase;Acc:XB-GENE-1009985]) HSP 1 Score: 63.5438 bits (153), Expect = 2.797e-9 Identity = 75/285 (26.32%), Postives = 131/285 (45.96%), Query Frame = 3
Query: 1008 EAMSKHDTKF----LLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITAT--VWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSI-KRTIIFASTDDDILLVYKYLMQK 1832
E +S++ TK L +Q + IP IL G + +A A GK+ L+P+L + + ++ S+ P AII+ + + ++++ A KF+ RP +V Y G M V +GC++L TP L+ + + E L++L+ LD+A+ ++ + E LI G + + +AT RL S K D + V L V+Q I+E ++ Y+K +E+ +SS +RT+IF +T ++ YL Q+
Sbjct: 261 ETLSRNVTKAGYVKLTPVQKHSIPIILAGRDLMACAQTGSGKTAAFLLPILSHMMNEGITASQFLPLQEPQAIIIAPTRELINQIYLDARKFS-----YGTCVRPVVV--YGGIHPVHAMRDVERGCNILCATPGRLMDIIGR-EKIGLSKLKYLVLDEADRMLDMGFAPVMENLI-GSPGMPAKEERQTLMFSATYPAEIQRLAS--KFLKSDHLFVVVG--LVGGACSDVEQTILEIQE-----YRKRDKLVEILQSSGNERTMIFVNTKKKADVIAGYLCQE 527
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Match: Tdrd12 (tudor domain containing 12 [Source:MGI Symbol;Acc:MGI:1919231]) HSP 1 Score: 159.458 bits (402), Expect = 9.584e-39 Identity = 180/714 (25.21%), Postives = 313/714 (43.84%), Query Frame = 3
Query: 954 VRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIA--PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPR-----IVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHE--FFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFITATV-WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV-SEPS-FGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVV---SKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARL 3023
+ P L+ + L A LK+A+ ++ SY P I RG + + I+ + L+ +LQ + PSR PLA+I+C WKK A+ + D RP + + K M + +GCDV++ TP+ LL L F +L L LD+ + E E + IL K +R S P Q + V W ++ V+ M D V LE A + Q+++ + +E + L+ L+ S ++T+IF + + V K + + LKM L ++ +W + + +L ++D+ + + I +A ++H S P G RL + D + L+ S E +K + + T N A + R+L R + P L E + + KE K +CP +K FG CK C RH + ++D P LP GHI+ Y+ + +++F RI + + Y +L +M YF N ++ ++GL ++ K L +RV V S+ + G + VKLID+G ++ + LL LP++ +PPQA+E V ++P D++ ++ + + + + K A + L +G+TLWID + + + ++ D N+ +L + NS+H+E+L +L
Sbjct: 381 IEPCLTLEKSPLSAD-LKKALQRNKFPGPSHTASYSWPPIARGCDMVVISHCGNDPLLYLPPLLTILQMGGCYKSLPSRN-GPLAVIVCPGWKK-------AQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAKNMKLP---RGCDVIVTTPHSLLRLLTYRSLLFLRLCHL---VLDEVHMLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWNKHIDHLVREFMKD--PCVVITALEEAALYGSVQQVV-HLCLECEKTSTLLQVLDFVPSQAQKTLIFTCSVAETETVCKVVESNSIFCLKMHKEMAF--NLKSILEQWKKKLSPGSHIVLTLTDDCIPL--LAITDATCVVHFSFPSSPKVLGGRLYCMSDHFQSLTEQGSPAEQGDKKTKSVLLL-TERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIID---------KHVDLYETLNAEMNEYFKESSNKTSAE-KVENLGLYG-LEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKL 1060
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Match: Tdrd12 (tudor domain containing 12 [Source:MGI Symbol;Acc:MGI:1919231]) HSP 1 Score: 108.997 bits (271), Expect = 3.771e-23 Identity = 84/306 (27.45%), Postives = 147/306 (48.04%), Query Frame = 3
Query: 2136 TTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVV---SKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARL 3023
T N A + R+L R + P L E + + KE K +CP +K FG CK C RH + ++D P LP GHI+ Y+ + +++F RI + + Y +L +M YF N ++ ++GL ++ K L +RV V S+ + G + VKLID+G ++ + LL LP++ +PPQA+E V ++P D++ ++ + + + + K A + L +G+TLWID + + + ++ D N+ +L + NS+H+E+L +L
Sbjct: 705 TERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIID---------KHVDLYETLNAEMNEYFKESSNKTSAE-KVENLGLYG-LEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKL 999 HSP 2 Score: 53.9138 bits (128), Expect = 2.609e-6 Identity = 67/258 (25.97%), Postives = 107/258 (41.47%), Query Frame = 3
Query: 1053 SYMIPNILRGFNTLAIA--PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRP-----RIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHE--FFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFITATV-WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFAST 1790
SY P I RG + + I+ + L+ +LQ + PSR PLA+I+C WKK A+ + D RP + + K M + +GCDV++ TP+ LL L F +L L LD+ + E E + IL K +R S P Q + V W ++ V+ M D V LE A + Q+++ + +E + L+ L+ S ++T+IF +
Sbjct: 438 SYSWPPIARGCDMVVISHCGNDPLLYLPPLLTILQMGGCYKSLPSRN-GPLAVIVCPGWKK-------AQFIFELLGDYSMSSRPLHPVLLTIGLHKDEAKNMKLP---RGCDVIVTTPHSLLRLLTYRSLLFLRLCHL---VLDEVHMLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWNKHIDHLVREFMKD--PCVVITALEEAALYGSVQQVV-HLCLECEKTSTLLQVLDFVPSQAQKTLIFTCS 678
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Match: Ddx41 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 [Source:MGI Symbol;Acc:MGI:1920185]) HSP 1 Score: 60.077 bits (144), Expect = 2.427e-8 Identity = 84/357 (23.53%), Postives = 144/357 (40.34%), Query Frame = 3
Query: 894 WTVQKY-------RTENETTDFNYL----GSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI--ATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYR 1916
WT +Y R E ++ L G PI S+K K A L+ + K IQ IP IL G + + IA GK++ +PV+ K+L S+ P +I+C S + + E + R ++ D R G K M + G +++ TP L+ L Q + L+ LD+A+ +I E ++ I Y +G + +AT+ +++++ K + +I V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G EE + + + +
Sbjct: 157 WTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILR-GLKKKGILHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCR-LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLL-QKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYF------KGQRQTLLFSATM-PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEV-----EYVKEEA----KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKG-VEAVAIHGGKDQEERTKAIEAFREGK 493
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Match: Ddx41 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 [Source:MGI Symbol;Acc:MGI:1920185]) HSP 1 Score: 59.6918 bits (143), Expect = 3.406e-8 Identity = 84/357 (23.53%), Postives = 144/357 (40.34%), Query Frame = 3
Query: 894 WTVQKY-------RTENETTDFNYL----GSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI--ATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYR 1916
WT +Y R E ++ L G PI S+K K A L+ + K IQ IP IL G + + IA GK++ +PV+ K+L S+ P +I+C S + + E + R ++ D R G K M + G +++ TP L+ L Q + L+ LD+A+ +I E ++ I Y +G + +AT+ +++++ K + +I V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G EE + + + +
Sbjct: 146 WTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILR-GLKKKGILHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCR-LLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLL-QKKMVSLDICRYLALDEADRMIDMGFEGDIRTIFSYF------KGQRQTLLFSATM-PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEV-----EYVKEEA----KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKG-VEAVAIHGGKDQEERTKAIEAFREGK 482
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Match: Ddx4 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Source:MGI Symbol;Acc:MGI:102670]) HSP 1 Score: 57.3806 bits (137), Expect = 1.855e-7 Identity = 44/175 (25.14%), Postives = 84/175 (48.00%), Query Frame = 3
Query: 963 ILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENII 1478
IL+++ L T L ++K L +Q Y IP +L G + +A A GK+ L+P+L + ++ SR P II+ + + ++++ A KF+ R V Y G+ ++ ++QGC++L TP L+ + + E L +++ LD+A+ ++
Sbjct: 260 ILTFEEANLCQT-LNNNIAKAGYTKLTPVQKYSIPIVLAGRDLMACAQTGSGKTAAFLLPILAHMMRDGITASRFKELQEPECIIVAPTRELINQIYLEARKFSFGTC-------VRAVVIYGGTQFGHSVRQIVQGCNILCATPGRLMDIIGK-EKIGLKQVKYLVLDEADRML 425
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Match: sp|Q587J7|TDR12_HUMAN (Putative ATP-dependent RNA helicase TDRD12 OS=Homo sapiens OX=9606 GN=TDRD12 PE=2 SV=2) HSP 1 Score: 173.711 bits (439), Expect = 3.545e-42 Identity = 188/733 (25.65%), Postives = 323/733 (44.07%), Query Frame = 3
Query: 954 VRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLL--MPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFITATV-WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDIL-IYNAEIILHVD--VSEPSFGNRLNFLRDKYAKLSFLKSRNEPIE----KCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVK---VKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVP 3086
++P L+ + L A LK+A+ ++ +SY P I RG + + I+ + LL + VLQT A + PSR PLA+I+C WKK + E + + S + + + K T +P +GCDV++ TP LL L L + LD+ E + E E + IL K +R S P Q + V W +E +K M D + I + E A+ V+Q + + +E + L+ L+ S ++T+IF + + +V K + + LKM + L ++ +W + + IL ++D+ C +L I +A ++H S FG RL + D F + P E K S + + T + A + R+L R + P L E + + KE K +CP +K FG CK C RH + + D P LP+ G+I+ Y+++ +++F RI + + Y +L +M YF + + + V L + K L RV V ++ + + V+ ID+G +V + LL LP+ +PPQA+E V ++P DN+ ++ + + + + K A + L +G+T+WID + + + + +V D N+ +L + N +HIE+L +L + D P+ EES + P
Sbjct: 412 IKPCLTIDSSPLSAD-LKKALQRNKFPGPSHTESYSWPPIARGCDVVVISHCESNPLLYLLPVLTVLQTGACYKSLPSRN-GPLAVIVCPGWKKAQFIF---ELLGEYSMSSRPLHPVLLTIGLHKEEAKNTKLP--RGCDVIVTTPYSLLRLLACQSLLFLRLCHLI-LDEVEVLFLEANEQMFAILDNFKKNIEVEERESAPHQIVAVGVHWNKHIEHLIKEFMNDPY-IVITAMEEAALYGNVQQVV--HLCLECEKTSSLLQALDFIPSQAQKTLIFTCSVAETEIVCKVVESSSIFCLKMHKEMIF--NLQNVLEQWKKKLSSGSQIILALTDD---CVPLLAITDATCVIHFSFPASPKVFGGRLYCMSDH-----FHAEQGSPAEQGDKKAKSVLLL--TEKDASHAVGVLRYLERADAKVPAELYEFTAGVLEAKEDKKAGRPLCPYLKAFGFCKDKRICPDRHRINPETDLPRKLSSQALPSFGYIKIIPFYILNATNYFGRIVD---------KHMDLYATLNAEMNEYFKDS---NKTTVEKVEKFGLYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEGRTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHHKIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKL---REDAKIPACEESLSQTPP 1106
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Match: sp|Q1XG89|TDR12_BOMMO (Putative ATP-dependent RNA helicase TDRD12 OS=Bombyx mori OX=7091 GN=TDRD12 PE=1 SV=2) HSP 1 Score: 155.221 bits (391), Expect = 2.590e-36 Identity = 214/872 (24.54%), Postives = 372/872 (42.66%), Query Frame = 3
Query: 1020 KHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSE--PSQFITAT-VWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDL-----YQKLVAYLELTES--SIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSE--PSFGNRLNFLRDKYAKLSFLKSRNEPIEKC--HSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKE---KSKGSNEICPRIKCFGEC-KLPGCVKRHMVLSDIDKPL--LPNKGHIQFRLLYLVSPSHFFVRI--NEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMN--IHGVNLRLVHVGLLAAI-KIKDLLERVVVSKMKS---NQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTF----LEEKDLY--AIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSL-----IFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVL--FYRDQCWHRGYVIKI--DCDVKIFSLDEGLIENYDHSREQLKKLPYEY-QQTPYQAILCNL 3503
KH T+ +Q+ ILRG +T I+PPR GK+MG L V + + + + P II+C++ K VSE+ E+ ++ ++ + ++ A Y+G +L GCD+LI TP ++ L+ L +L F +DD E I + ++ +L + +R ++ Q + A+ +W LE I + P + I Q++I Y I + K+ L+ +S KRT++ D+++ V L V + +M+ +L + W + PIL+ D L + + +A ++H + +F R + L D Y + +SR+ ++ S + P LN FL RC + P+ L E S + ILN++ K K +C + G C C +RH + + D P +P G + F++LY S + R+ N G + ++P + LSLKM M YF+ + + +HG+ + VG + A+ K ++ R V K+ S N + YV +KLID+ L LP E ++ ++ + I+P D D + SCL N + +DL+ + + +GS +++D++ + + TV N LL+ + V N +H+ L +C I K TN +V + +PVL E S ++ S+ +F+ ++ L +EIN + S + + +G VL F D + R + I + VK F +D+G + D S L + + Q P+QAI C L
Sbjct: 601 KHPTR----LQTVSWGTILRGLSTFLISPPRSGKTMGYLPAVCRLVRDFRKESPDSCGPKCIIVCATSKSVSEV----ERISKMLLGLED----KVFACYSGMDNLSVTTALLNGCDLLICTPKSIVRLLQNDLSVDLRDLTTFVVDDCERISDVYSNEVKYVLYEIKNMLKNRVNKELKVQIVVASRIWCDFLE-----------PIVLKAPDSVVCIGAF-QELILYSKISTTVDFLRPENKIANVLQFIDSVQGPKRTVVVCRADNEVKAVESSLRYNNRV-VFACDNTMNIHDLYNLNVVWGDFEDPTLGPILVCCDSNL--VHLNVTDASYLIHYSLPALFSTFCKRFSVLNDNYPSIFKNESRDLKVKVLMDESNVEQLPKILN---------FLKRCTENVPKILDEVS-EKILNEKDLAKVKDLVPLCDNLLSLGICPDTWNCTERHRIFKECDSPADWIPKNGVVTFQILYFHSAVMYSARLLSNTVDGET-TKYPQTYSTLSLKMGM--YFSKESSRRLHGIPM----VGDVCAVSKKQNFFIRCQVVKIISFYKNGNPNYVVIKLIDEEKFEQSRDIYLYHLPDEFKDMKTYVVQVRLANIQPQDKDITF---SCLAKNELEKIVEKNEDLFMRGHVAMSVGSCIFVDTLEACLDLSSLSETVVRHNFKQELLNAHAV-PNPKHLSILEEMCEKSGLIVK-----------------AVTNEQVVPKPIPVLPAAQWAHLEDDLSSVYLASVEDMDKLFVRLVKFESCMKLLNIEINKYV-SENTVPLDGSNVGDIVLAKFPDDSMYERARIDHIYSEDKVKCFFVDQG--DWRDVSTNDLATITENFITQLPFQAIECRL 1404
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Match: sp|Q9CWU0|TDR12_MOUSE (Putative ATP-dependent RNA helicase TDRD12 OS=Mus musculus OX=10090 GN=Tdrd12 PE=1 SV=2) HSP 1 Score: 108.997 bits (271), Expect = 2.727e-22 Identity = 84/306 (27.45%), Postives = 147/306 (48.04%), Query Frame = 3
Query: 2136 TTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKP------LLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVV---SKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARL 3023
T N A + R+L R + P L E + + KE K +CP +K FG CK C RH + ++D P LP GHI+ Y+ + +++F RI + + Y +L +M YF N ++ ++GL ++ K L +RV V S+ + G + VKLID+G ++ + LL LP++ +PPQA+E V ++P D++ ++ + + + + K A + L +G+TLWID + + + ++ D N+ +L + NS+H+E+L +L
Sbjct: 704 TERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIID---------KHVDLYETLNAEMNEYFKESSNKTSAE-KVENLGLYG-LEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEGRTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHHKIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKL 998
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Match: sp|P19109|DDX17_DROME (ATP-dependent RNA helicase p62 OS=Drosophila melanogaster OX=7227 GN=Rm62 PE=1 SV=3) HSP 1 Score: 67.781 bits (164), Expect = 7.212e-10 Identity = 85/364 (23.35%), Postives = 159/364 (43.68%), Query Frame = 3
Query: 894 WTVQKYRTENETTDFNYLGSV-RPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQK-LVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ VQ+YR E E T G V PI + L +KE + + K IQ+ P + G N + IA GK++G ++P + I +Q R P+A++L + + ++ A +F S VR + G+ K M + +GC+++I TP L+ +L L LD+A+ ++ E +++I+ R DR + + + W ++ + +G+ I + LEL+ ++Q + ++ + K L++ + T S + IIF T + + +++ + V + G S E + ++RE+ G N IL+ +D A R D+
Sbjct: 259 YEVQRYREEQEIT---VRGQVPNPIQDFSEVHLPDYVMKE-IRRQGYKAPTAIQAQGWPIAMSGSNFVGIAKTGSGKTLGYILPAIVHINNQQ-PLQRGDGPIALVLAPTRELAQQIQQVATEFG----SSSYVRN---TCVFGGAPKGGQMRDLQRGCEIVIATPGRLIDFLSAGS-TNLKRCTYLVLDEADRMLDMGFEPQIRKIVSQIRP---DRQT----LMWSATWPKEVKQLAEDFLGNYIQINIGS-LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNLVRFI-RSFGVRCGAIHGDKSQSERDFVLREFRS--GKSN--ILVATDVAARGLDV 596
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Match: sp|Q755N4|DBP2_ASHGO (ATP-dependent RNA helicase DBP2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=DBP2 PE=3 SV=2) HSP 1 Score: 62.3882 bits (150), Expect = 3.348e-8 Identity = 85/364 (23.35%), Postives = 153/364 (42.03%), Query Frame = 3
Query: 900 VQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMP-VLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLN--ELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLEL-TESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
V+++R ENE + +PI ++ LKE + K IQ P L G + + +A GK++ +P ++ A LSP P+ ++L + + ++ KF R S ++R Y G K + + +G ++LI TP L+ L E K N + LD+A+ ++ E +++I+ R DR + + + W ++ + + D + + LELA + Q + D D +LV +LE+ ++ + IIFAST + YL Q L + G +E + ++ E+ R PI++ +D A R D+
Sbjct: 93 VEQFRKENEMKIVGH-DVPKPIRTFDEAGFPEYVLKEVKEEGFEK-PTAIQCQGWPMALSGRDMIGVAATGSGKTLSYCLPGIVHINAQPLLSPGD--GPVVLVLAPTRELAVQIQKECSKFGR----SSRIRN---TCVYGGVPKSQQIRDLQRGVEILIATPGRLIDML---EIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRP---DRQT----LMWSATWPKEVQQLARDYLHDPIQVNIGS-LELAASHTITQLVEVVSDF--DKRDRLVKHLEIASKDKDSKIIIFASTKRTCDEITSYLRQDGWPALAIH-GDKQQQERDWVLNEFRTGRS----PIMVATDVAARGIDV 427
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Match: A0A210PGL2 (Tudor domain-containing protein 12 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13850 PE=4 SV=1) HSP 1 Score: 253.832 bits (647), Expect = 6.186e-64 Identity = 245/904 (27.10%), Postives = 430/904 (47.57%), Query Frame = 3
Query: 954 VRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR-----TYN-PLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILI-YKRT--GAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIK---RTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV--SEPSFGNRLNFLRDKYAKLSFLKSRN-EPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKS-KGSNEICPRIKCFGECKLPG-CVKRHMVLSDID-----KPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAI-KIKDLLERVVVSKMKS-NQSGGYVKVKL--IDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLI--DSIEALSISDIKIGSKVLFYRDQCWHRGYVIK--IDCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSD---DVIAAIKHY 3566
++PI + +D L ++E + + +Q Y P +LRG N + I+P GK+ L P+L T L PS T N P AIIL WK + D T+ ++ + R R++ AY G ++ ++P++ GC++LI TP L S L Q ++ L L +DDAE ++ E E +Q+ +I Y R ++R + + ++ W + + S++ + D ++ + E A+ RVKQ + + Q + +LEL S + + IIF S + L ++K L ++ L + M L + EW IL+ +DE++ ++ I +A I+H ++ S+ FGNRL+ + Y S + N +P S+I I T + R + + L R S P L S+ LN+EK+ G ++C +K +G C+ C RH +L ++D +PL N G ++ + +V SH+FVR+ E + + S L L+ KMA +F + H + +G + A+ + ++ RV V + N G +K +L +D G + V L LP L ++P QA+E ++ ++P+D DE ++ ++ +F L++K + I L IG+TLW+D + +R++ + + + LL NS H++ L LC GKI++ K +L+ E N + E LP +++ + S + SP+LI+L T K L + EIN + + + + I +K GS L D W+R +++ D V++F +D G E SR+ L+K+P E+ + P+QAI L + + ++ + D+I + H+
Sbjct: 599 LKPIYNI-HDTPLDPIIREGLDNYGIVAPKFVQCYTWPALLRGRNVVGISPSGSGKTFAYLAPLL----TDLLKPSNYKDIPTGNGPYAIILVPFWKSAQMVYDV----TKILLGNS--RSFRVLVAYGGGNEENQVVPLINGCELLITTPRSL-SRLLQQKYTHLERLCHVVIDDAEIVLEEFREEIQDFMISYSRVVEEHVERSAPREVLVFSSRWCNMVNSFIDAFIPDP-TLIITSRFEAAIYGRVKQIPLLWR-----TDQLVSQFLELVNSLAQENSKMIIFCSNVNTTLHIHKLLKSRSLYSL-LTHDKMDTLMLEQIGGEWEGPSD--KGKILICTDESVE--ELKIVDATAIVHYELPSSKTKFGNRLSTMSKYYHNSSSKEKINIDPT----SYILI--TEDSGRQVETILQLLKRTKSKIPRNLY--SMVMGLNQEKNCDGDKDLCVALKAYGSCRYQNKCPARHALLPEVDCKATQQPL--NSGEVKVLVTNVVDASHYFVRLLEHRPPTGDKVDTSMTMLDLRFKMAEWFGDLQ--HRSKYSSLCIGEMCAVSEDEETYHRVKVCDITGVNSPGDRIKAELMFVDDGRKSFVSPNKLYNLPPHLRDVPYQALEVFICRVQPVDLDEKWTSKASMFVYDLLDKKTMDGRIVLRIGNTLWLDPLVERVYLSDLHAYCTNLFVRSELLKNGFAVNNSNHMQLLYDLCKGKIEVPKLNLQSDRSEK----------KNEV--EILP----ESKEYHDVHLSAVNSPTLIYLQRSDTFKLLEKMNDEINERMKNEELTGMKIISLKTGSVCLGKWDDMWYRVRILEELEDNMVEVFHVDFGDSETV--SRDSLQKIPQEFLELPFQAIEAGLSYVAPQGETWEEAAGDLIWDLAHF 1449
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Match: A0A2B4S274 (Putative ATP-dependent RNA helicase TDRD12 OS=Stylophora pistillata OX=50429 GN=TDRD12 PE=4 SV=1) HSP 1 Score: 234.572 bits (597), Expect = 3.707e-58 Identity = 211/859 (24.56%), Postives = 408/859 (47.50%), Query Frame = 3
Query: 1044 IIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVL-QTIATKQLS---PSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIY--KRTGAIDRGSEPSQ-FITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECK----LPGCVKRHMVLSDIDKPL--LPNKGHIQFRLLYLVSPSHFFVRI----NEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKD-----LLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVL--FYRDQCWHRGYVI--KIDCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSDD 3542
++Q++ P +LRG + + I + L+P++ Q + +++ P + P +IL +W V ++ + R I+ +K R +++ + + +IP+L GC++LI TP C L L+++ + L+ L DA+ ++ E ++ I+ + K + S P Q + A+ W++ + S VK +G+ I + D +E A+ V+Q + + + D+ +L+ YLE + S K +F ST + V + L L + + P EL+ + R+WN MP+L+I+++ + + I NA ++H + G+++ F + S +E C S IF+ N+ + + + R G + P+ L + KEK K ++C +K FG C+ + C+KRH VL+++DKP +P G ++ ++ ++ + ++VRI + ++ S+++L L M ++ ++ + H V LV VG L A+K+ + ++ V+K ++ V+V+ +D+G+ V LLQLP + P QA+E +V ++P+D D +++E+ + +E K++ + L +G+T+W+D + +R + VT N+ + LL + +N QH+ L LC G ID+ ++ + V P E + + ++ S + +P L F+ K++ +SL DL+ +INS + +E+ ++I IGS + F D W+R V+ + D + +F +D G E R + Q P QA+ C L L +S++
Sbjct: 669 LLQAHAWPTLLRGRDLVGICQANDAQIQAYLLPIIYQLVEEREVYADLPKLSSGPQFLILAPTWGAVVDI----HRQCRLILAKNKNIRVQLI--FAAGAEDNQIIPLLNGCEILIATPPCFLRMLRKY-YISLDRLCHLVFHDADIMVEEFTSEIKCIMRHYAKLLQSQPCLSAPRQGVVMASSWSAGVASLVKAYLGNPVVI-IPDMIEAAIYRGVQQIVTFCSESQRDV--ELLGYLE-SFISTKDICVFTSTAAEAEDVGQILNANCYFAL-VAHNFLPPHELDSIQRQWNTPHTTDTMPVLVIAEDVI--GQLNITNASCVIHFNFP----GSKMRFSKRLATLAGTFTSSDE--HGCVSVIFVT-DGRNMYHTPSIRQLVQRSGQEVPQLLDAMADLAEQEKEKVK---DLCYSLKAFGTCRYKRGIRNCLKRHSVLAELDKPAKGIPTSGIVKVLIMSVMDATCYWVRILGHKATDANQRNSQTADSTEFLELTMAVSRWYADPN--HRVKQELVSVGDLCAVKLNNSSSYNRVKVCFVTKEDHSKKPVEVRVQYVDRGNFECVHVDRLLQLPPQFRSCPFQAVEVFVCRLQPLDKDTDWTDETAAYVTRLIEGKEMEGKVVLSLGNTMWLDPLVERKYLPNINVTTNALNVRMELLREKRAAENKQHVRLLRNLCEGVIDLQPLEGGQTGLSDV--------CEQPTALETIVLPEEGFH---SVYVSAVENPGLFFVQLKSSEESLEDLKQKINSGVSKVESEE-NEISIGSLCVAKFSEDNLWYRARVLGSRPDKEYDVFYVDFGDREWVTADR--IVPAWNGILQLPLQAVECALVNVDPLEKEWSEE 1487
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Match: C3XUE7 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_120982 PE=4 SV=1) HSP 1 Score: 228.794 bits (582), Expect = 3.033e-56 Identity = 207/853 (24.27%), Postives = 388/853 (45.49%), Query Frame = 3
Query: 999 FLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVL----QTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEIL-IYKRTGA--IDRGSEPSQFI-TATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVD--VSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSA-NFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKPL--LPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIK-IKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDI--WKPSLEESTIEHVPIMRKFTYTN-NPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIG--SKVLFYRDQCWHRGYVIKIDCD--VKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAI 3491
F+++ + D +Q+Y P I+RG + +A+AP + GK++ L+P++ QT + L P +IILC W + D + +I D + ++ + + MIP++ GCD+LI TP CLL L++ + L+ L +DDA+ + + + ++ ++ +Y + A DR S P Q + A WT+ +ES+ + M + +E AV +VKQ ++ Y +L++ L+ E + + ++F +D + V + L + L T + E++ + +EW+ + + P+L+++D ++ D+ I +A ++H +S F RL + + K + + + P C S+I + T + L R G + L + L K+ + N C +K FG C C RH+VL ++D+P +P G+++ + ++V + ++ RI + P + L L + +++ Q N V + VG + A++ +++ RV V+K+ + +V +D+G +E LL A+E ++ G+ PID D+ +++++ FT+ + K+L + LC+G TLW++S+ +R + T N+ L+ L + N H+ L + C GKI + +KP + P Y+ NP LP D E S + P L+++ K + L L E+N+ A ++ + G +F +D W+R V ++ D ++F LD G + R LK+ E Q P+QAI
Sbjct: 724 FIQQYLISQDFPAPSKVQAYCWPAIMRGRDLVAMAPAKMGKTLAYLLPLMTQLAQTAGMEGLPEGN--GPRSIILCPYWNTARYVYD---QCWNYIADRKSTK---VLLIFGAGAEDDQMIPLINGCDLLIATPRCLLRMLEKG-YTNLDRLCQLVVDDADTLTEVYTDEIKSLMRLYGKVIADQPDR-SAPRQIVLMARQWTAGIESFHRAYMTQPL-LVFTSKVEEAVYSKVKQFVLVVPSTL--RYTQLLSLLDQCEGAGHKIVVFVGSDTEAEDVTQLLKSYSHSTLYAHT-DLHQYEIDKVKKEWSTHHSRGSQPVLVMTDTVIQ--DLHIRDATCVIHYSFALSPLKFSARLGCMSHSFNKDATKEKKKSP--GCVSYILVTETCTTFPVGLQEIVTLLRRSGGHVLQELLDMCNKAWLAKQVGRVDNSFCHAMKAFGHCAEQARCKARHVVLPEVDQPGEGMPTVGYVKVLVTHVVDANCYYGRIVKHWDWDRRAVPRENTCLPLMADIGLHYSRQEN--KVPVLTAQVGDMCAVRDMQNTFHRVRVTKITATDFTSRARVFYVDEGKTEELEVTKLL------------AVEVFLCGVCPIDQDKQWTDKASAFTHALVSSKELDGRVALCLGHTLWMESLVERKVLPGIKATTNKHNIRRELVHVCLAENNPDHVSLLRQACDGKITLPEYKPPSKAP-----PAKSGLKYSRANPPPTATLPGGGFD-----EVYVSAVEHPGLMYVQRKHYARKLEVLTAEVNNEEKLAAAPALQQVAPGRLCVAVFPQDNRWYRARVEELQGDEMCEVFYLDHG--DTAIIPRSSLKEPWKEVMQLPFQAI 1532
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Match: K1R0K8 (Tudor domain-containing protein 12 OS=Crassostrea gigas OX=29159 GN=CGI_10028859 PE=4 SV=1) HSP 1 Score: 225.713 bits (574), Expect = 2.231e-55 Identity = 222/899 (24.69%), Postives = 400/899 (44.49%), Query Frame = 3
Query: 975 KNDKLLATFLKEAMSK---HDTKFL--LIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYN--PLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAID--RGSEPSQFIT-ATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV---SEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPL--LPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGG----YVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIE--ALSISDIKIGSKVL--FYRDQCWHRGYVIKI--DCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSD---DVIAAIKHYAIGTDKN 3587
+ D++LA SK D +F ++IQ+Y P IL+ + + I+P + GK+ L P+L + Q PLA+IL SSWKK + D R + RRPR + Y G + IP++ GC++LI TP CL+ + + + L L +DDAE ++ E+ E +Q+I+ + + S P Q + T WT + S+ + M D +I + E A+ +V Q++ + +L+ L+ + + IIF +T +D+ + + L++ S+ + M E+ ++ +W+ + +L+ +DE + D+ I +A ++H D+ S+ FGNRL+ +R YAK S + + K S+I + + + +S+ +L + K+ E+ + + + C RH++L D+DKP G ++ + +V+ + ++ R+ E S+ LS+ ++ N+F+ + N + L V G + AI D RV + +K + S G +V +D+G V L +LP L P Q +E Y+ +RPID DE ++ + + + L++K L+ I L IG T+W+D + +R H ++ T+ + LL N QH++ L LC G + + P+LE T N+ + E +L + + C+ S P LIF+ +K + + IN + E + S K+G+ L + +D W+R +++ + K+ D+G E +R L +P E + P AI C L + + D I + H G +K+
Sbjct: 559 QGDRILANLSGGVKSKLILKDFEFPSPMLIQAYGWPGILKLNHVVGISPVQTGKTFTYLCPLLSELLNPQSYQELAIGNGPLALILVSSWKKAQGVYDITRGLLR------EHRRPRPLIIYGGGCEHNQYIPLMNGCEILIATPPCLIRMINRR-YTDLQRLCHLVVDDAEIVLKEYSEEVQKIMEWFAEARKENLHKSVPYQVVAMGTQWTPPVLSFTQAYMLDP-TIVITSRFEAAIYGKVTQQV--HMCPSSLRSTRLLELLDAILNKGMKVIIFTTTVNDVCFIME-LLKSHSLCCNKIHHQMDSYEVEAVLHDWSSGLEKDSPKLLVCTDECV--DDMKIDDANAVIHFDLPSESKTRFGNRLSCMRKYYAKYSESEEEEGQLVKPMSYILMTEHSTG----------------------QARSVRDLLKRLKTPIPRELAAMLAGMKQSR---CPHRHIILPDVDKPANSFLTSGEVKICVANVVNATCYYARVLEHRAQDGTLTDLSTTTLSITFELKNWFSVEKNC--IRLGNVCAGDVCAIVEDDSFFRVQIQDIKWSNSPGSNIMQAQVFFVDEGRVKDVSIIKLYELPPHLKSYPFQTVEVYLCRLRPIDRDENWTSNADQYAHELLQDKVLFGRIVLSIGHTVWLDPLVERQHLKGSQTTINKMYIRSELLHNGYAVDNEQHVQNLYELCEGLLPV--PNLEN------------TQENSELSVET-DLLPESEEFHKVCI-SACDDPGLIFVQRCVFVKQMDAMVDTINDRLQKGEFTPMKASCCKVGTICLGKYTQDDTWYRVKILECLEGGEYKVIFCDQGDTEVLALNR--LNPIPQECFEIPMLAIECELAHVQPRGKKWDEKVGDAIWDMTHTVAGGNKH 1399
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Match: A0A1S3IWQ2 (uncharacterized protein LOC106167688 OS=Lingula unguis OX=7574 GN=LOC106167688 PE=4 SV=1) HSP 1 Score: 224.557 bits (571), Expect = 6.537e-55 Identity = 254/1060 (23.96%), Postives = 488/1060 (46.04%), Query Frame = 3
Query: 1023 HDTKF--LLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTY-------NPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILI-YKRT-GAIDRGSEPSQFI-TATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV--SEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECK-LPGCVKRHMVLSDIDKP-------LLPNKGHIQFRLLYLV-SPSHFFVRINEFSGNSEAEF-PYSSQYLSLKMKMANYF---NNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQ--SGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSI-EALSISDIKIGSKV--LFYRDQCWHRGYVI--KIDCDVKIFSLDEGLIE--NYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSDDVIAAIKHYAIGTDKNTSLIISVYKEENVDSKMFGDSEIFSQLNDDELFLFLKRYXXXXXXXXXXXXDRMLHYVLIRNQHILPSLTWIHDVLPESRPFSSRLERNGSIPHLSADILSTKDGAKRLRISQTIERIIENKIKSYEASGSINENMASFIHGLTILIHFMNEKSEFMCIYRSINRLLSL 4094
+D KF +++Q+Y+ ++R + +A++PPR GK++ L+PV+ I + TY PLA+I+ SWKK ++ D F D+ + + Y G ++ IP+L GC +L+ TP CLL +++ + LN L +DDA+ + + + + +++ Y + ++ S P Q + + WT + S+ M D I + LE ++ VKQ + Y + Q+L+ L K+ IIF ++ D + + + L ++ L +S ++L + ++WN + P+L+++DE ++ ++ + NA +H + ++ +F NR + + +F +S+ E S+I I T A + + L R S P+ L + ++ + ++ + S +C +K FG C+ C RH+V+ + D P LP G ++ + +++ S S F+VR+ E +E F ++ Y+ L + M +F +NQ+ + + + A + RV ++ + ++ + V+V+ +D G V ++ +L+LP+ E+P QA+E Y+ I+P+D+D ++ ++ F + +E+K+L I L +G+TLW++ V R+ TR +L LL L N QH++KL LC GK+DI + + +++ + + + T E LP +++ E + I SP + + + K + L EIN + I + S DI G+ V LF D W+R V+ + +V + +D G E +D +++ LP +Y+ P+QAI C L + + + A + + D I V K N M+G + + Y ++ D ++ + HI + I +V+ S+ + ++ IP L A + + D +RL I++ ++R + N S I E I G+ +L +N+++ C+ + L+S+
Sbjct: 1042 YDRKFGAPILVQAYIWRPMMRARHVVAVSPPRSGKTLAYLLPVISHILQRD-----TYKDVPAGNGPLALIVTPSWKKAQQVFDWCYDFLGGRPDA------KTLIIYGGGSEEDQYIPLLNGCKILVATPYCLLRMIEKG-YTNLNRLCHLVMDDADVLTEDFTDQICQLMTGYTQVLRTVESSSRPQQIVMVGSQWTPGMASFKDTFMVDPLVI-ITSKLEASIYAGVKQSV--YMCVAAQRDQQLLGILNTFVLQDKKAIIFTNSTRDAIDLSQVLKSQSMYVLVAHKELLS-DQLEDIQKDWNIDHREGSKPVLILTDECIK--ELKLTNATCTIHFSLPDTKKAFVNRYGCMLE-----NFKRSQQEEQIVLTSYIII--TDQCTEQAQTVLQLLLRTKSYVPKKL-QTMVEDVKKAKEEEKSKPLCHYLKSFGVCRERQRCEHRHVVVKEQDTPGISKHHISLPTSGEVKVLVTHVIDSASCFYVRLQELRSETEDSFKAMAAAYVQLVLDMNMWFQVKDNQI----IQDEICEGTVCAVQDGQKCYHRVQITCIPQSEFETVKEVQVQYVDVGKLEWVPKSSILKLPQHFLEVPFQAVEVYLCCIKPVDDDTEWTRKAVEFVHQLVEDKELDGRICLSLGNTLWLNPVVSRVKLQCTRSFFHQFSLRKDLLRNGLAVNNLQHLDKLYELCEGKVDIVQRAPKDNMDDSLQSVTVAMET------EILP----ESEEYHEVYVASIDSPGIFHVQKREMEKKIVALIDEINEESEHILQDTSYVDITCGTLVLALFPEDDRWYRAQVLATRGHSEVHVLFVDYGEREWLVFD----KIRNLPEKYRTLPFQAIECCLADLAPREGQWKEGDTDAF--WDLVLDDQDQKIALVAKVINRSPAMYGGCHRY----------HIVLYDTESEDVTINIGDTLVTQGRAVSLHIPEEV--IEEVIIGSKHYDYPYQK---IPDLCAALQISTDEMRRLFIAKALQRTVMN---SANFKDEIRE-----IGGIRLLCGLLNQETSSECVEYLLLTLISM 2032
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Match: tdrd12 (tudor domain containing 12 [Source:ZFIN;Acc:ZDB-GENE-121214-348]) HSP 1 Score: 144.821 bits (364), Expect = 2.160e-34 Identity = 167/684 (24.42%), Postives = 302/684 (44.15%), Query Frame = 3
Query: 1044 IIQSYMIPNILRGFNTLAIA----------PPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKK--MTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATV--WTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV--SEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG--CVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKM--KSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGK 3035
+ +SY P++ RG +T+ + PP L+ LQ + +R P+A+ILC W+KV + D E DS A G LKK + + C +L+ TP L L+ H F L + LD+ + + + + IL + R A ++ E SQ I A W+ L+ + M + V P E AV V Q ++ D +++ L+ + S ++T+I ++ +++ VYK ++ A+ LK G + + +V +W + G IL+ ++++++ + I +A ++H S FGNRL + D + + K + P+ + S + + + N R + + R+L R + P L + S KE+ K +C +K G C+ C RH++ +D PL P+ G +Q LY+ S + ++ RI + Q+ L +M +++ + V + V G L A+ ++ RV V+K+ K ++ V ID G V+ LLQLP E +P QA+E + ++PID + ++ + + ++ K A + C+GST+W+D + + + + N+ ++ + NSQH+E L LC G+
Sbjct: 340 LAESYAWPSVARGCDTVLVVHGGNDPLTYIPP--------LLAQLQMASVFSALNTRK-GPIAVILCPGWEKVQYVLDLLE-------DSQAAASLHPAAVLLG-LKKDEAKNAKIQKNCQLLVTTPFSLARLLEVHCFLFLRLCHLV-LDEVSELYSRAPDQVT-ILKHFREVAREKSLECSQQIVAVSNQWSRELDGLITEHMVSP-CVVVTVPEEAAVYGGVLQTVLLCLDCNKT--SVMLSSLDFSPSVPQKTLIVTNSVEEVEHVYK-VVNTAAFSLKAHEGLSY--QFDFVVEQWKKDIGSGTQVILVTTNDSMKA--LGIRDATCVVHYGFPGSPKLFGNRLFCMSDNFQNQA--KKSSSPVVR--SVMLL--SERNARHVSGVLRYLKRTCATLPPELLQFSEGVQQAKEEQKIGRALCSHLKSLGFCRWESAVCPDRHIINRTLDHPLHPDSGTVQVLPLYIKSANVYYGRIVSQKQD---------QFKDLAAEMNSHYTEER----VFAKDVVKGGLYAVHEEEEYHRVCVTKVPDKEDKLFSSVTAHFIDDGYVQEVKSHQLLQLPSEFQSLPGQAVEIILCRVQPIDGEMDWNPKVTRAISLKIKGKLHQAKLIKCLGSTVWVDPMIRVTRVPGLSSFINEYNVHDEIIATGMGTINSQHLELLKTLCFGE 977
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Match: ddx4 (DEAD-box helicase 4 [Source:NCBI gene;Acc:103041190]) HSP 1 Score: 54.6842 bits (130), Expect = 8.484e-7 Identity = 76/326 (23.31%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMG-DKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESS-IKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHV 2009
+Q Y IP I + +A A GK+ L+P+LQ + ++ S+ P AII+ + + ++++ A KF RP +V Y G T+ VL+GC+VL TP LL + + + L++L LD+A+ ++ E L+ + + E + + + ++ + D +AV + V+Q II+ D Y K LEL +++ +RT++F T + +L Q+ V + G E + ++ + P+L+ + A R DI E + HV
Sbjct: 241 VQKYGIPIISAKRDLMACAQTGSGKTAAFLLPILQQLMADGVAASKFSEVQEPEAIIVAPTRELINQIYLEARKFAY-----GTCVRPVVV--YGGINTGYTIREVLKGCNVLCGTPGRLLDIIGRGK-VGLSKLRYLVLDEADRMLDMGFEPDMRKLV--SSPGMPAKEERQTLMFSATYPEDIQRLAADFLKVDYLFLAVG--VVGGACSDVEQHIIQV-----DQYSKREQLLELLKTTGTERTMVFVETKRSADFIATFLCQE-KVPTTSIHGDREQREREKALSDFRTGQ----CPVLVATSVAARGLDI-----EHVQHV 539
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Match: ddx4 (DEAD-box helicase 4 [Source:NCBI gene;Acc:103041190]) HSP 1 Score: 54.6842 bits (130), Expect = 9.541e-7 Identity = 76/326 (23.31%), Postives = 137/326 (42.02%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMG-DKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESS-IKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHV 2009
+Q Y IP I + +A A GK+ L+P+LQ + ++ S+ P AII+ + + ++++ A KF RP +V Y G T+ VL+GC+VL TP LL + + + L++L LD+A+ ++ E L+ + + E + + + ++ + D +AV + V+Q II+ D Y K LEL +++ +RT++F T + +L Q+ V + G E + ++ + P+L+ + A R DI E + HV
Sbjct: 262 VQKYGIPIISAKRDLMACAQTGSGKTAAFLLPILQQLMADGVAASKFSEVQEPEAIIVAPTRELINQIYLEARKFAY-----GTCVRPVVV--YGGINTGYTIREVLKGCNVLCGTPGRLLDIIGRGK-VGLSKLRYLVLDEADRMLDMGFEPDMRKLV--SSPGMPAKEERQTLMFSATYPEDIQRLAADFLKVDYLFLAVG--VVGGACSDVEQHIIQV-----DQYSKREQLLELLKTTGTERTMVFVETKRSADFIATFLCQE-KVPTTSIHGDREQREREKALSDFRTGQ----CPVLVATSVAARGLDI-----EHVQHV 560
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Match: ddx46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:103041720]) HSP 1 Score: 53.5286 bits (127), Expect = 2.049e-6 Identity = 41/172 (23.84%), Postives = 79/172 (45.93%), Query Frame = 3
Query: 900 VQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLK--EAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWL 1409
V +YR E E G +PI ++ T +K A+ KH+ + IQS IP I+ G + + IA GK++ L+P+ + I Q P+A+I+ + + ++ +KF++ + R+V Y G+ + + +G ++++ TP ++ L
Sbjct: 352 VNEYRLELEGITVKGKGCPKPIKTWVQ---CGTSMKVLNALKKHNYEKPTPIQSQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHI-LDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKPL-------GLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDML 512
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Match: DDX41 (DEAD-box helicase 41 [Source:NCBI gene;Acc:103035623]) HSP 1 Score: 52.7582 bits (125), Expect = 3.553e-6 Identity = 74/326 (22.70%), Postives = 133/326 (40.80%), Query Frame = 3
Query: 948 GSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI--ATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQ 1910
G PI S++ K LK + K IQ IP IL G + + IA GK++ +P++ K+L + P +I+C S + + E + + + D + + R G K M V G +++ TP L+ L + + L+ LD+A+ +I E ++ I Y +G + +AT+ +++++ K + +I V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G EE + + +
Sbjct: 167 GIPAPIKSFREMKFPQAILK-GLKKKGIVHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPIIMFCLEQEKRLPFCKREGPYGLIICPSRELARQTHSIIEYYCKLLED-EGAPQMRSALCIGGMSVKEQMEVVKHGVHMMVATPGRLMDLLNK-KMVSLDICRYLALDEADRMIDMGFEEDIRTIFSY------FKGQRQTLLFSATM-PKKIQNFAKSALVKPITINVGRAGAASLDVIQEV-----EYVKEEA----KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKG-VEAVAIHGGKDQEERTKAIEAFKE 472
BLAST of Tudor domain-containing protein 12 vs. Ensembl Sea Lamprey
Match: ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:NCBI gene;Acc:321948]) HSP 1 Score: 52.7582 bits (125), Expect = 8.344e-7 Identity = 39/176 (22.16%), Postives = 77/176 (43.75%), Query Frame = 3
Query: 882 KVKCWTVQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWL 1409
K+ V YR E E G +PI ++ + L + K + + IQ+ IP I+ G + + IA GK++G L+P+ + + Q P+ +I+ + + ++A KFT+ + R+V Y G+ + + +G ++++ TP ++ L
Sbjct: 341 KMTAEEVSAYRLEMEGVMVKGKGCPKPIKTWVQCGISMKILN-TLKKQNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIGFLLPMFRHV-MDQRPLEEGEGPIGVIMTPTRELALQIAKECRKFTKQLA-------LRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDML 507
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Match: DBP1 (Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs; protein abundance increases in response to DNA replication stress; DBP1 has a paralog, DED1, that arose from the whole genome duplication [Source:SGD;Acc:S000006040]) HSP 1 Score: 57.3806 bits (137), Expect = 1.560e-8 Identity = 53/191 (27.75%), Postives = 88/191 (46.07%), Query Frame = 3
Query: 960 PILSYKN---DKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSP---------SRTYNPLAIILCSSWKKVSELADAAEKFT-RFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE 1493
PIL + + D+LL +K A T +Q Y IP + +G + +A A GK+ G L P+ + SP SR P A++L + + +++ + A KFT R + RP +V Y G+ M V +GCD+L+ TP L L++ + L ++ LD+A+ ++ E
Sbjct: 152 PILDFSSPPLDELLMENIKLASFTKPTP----VQKYSIPIVTKGRDLMACAQTGSGKTGGFLFPLFTELFRSGPSPVPEKAQSFYSRKGYPSALVLAPTRELATQIFEEARKFTYRSWV------RPCVV--YGGAPIGNQMREVDRGCDLLVATPGRLNDLLERGK-VSLANIKYLVLDEADRMLDMGFE 329
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Match: DED1 (ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase; required for translation initiation of all yeast mRNAs; binds to mRNA cap-associated factors, and binding stimulates Ded1p RNA-dependent ATPase activity; mutation in human homolog DBY is associated with male infertility; human homolog DDX3X complements ded1 null mutation; DED1 has a paralog, DBP1, that arose from the whole genome duplication [Source:SGD;Acc:S000005730]) HSP 1 Score: 53.5286 bits (127), Expect = 2.154e-7 Identity = 41/159 (25.79%), Postives = 71/159 (44.65%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSP---------SRTYNPLAIILCSSWKKVSELADAAEKFT-RFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE 1493
+Q Y +P + G + +A A GK+ G L PVL SP R P A+I+ + + +++ D A+KFT R + + Y GS + + +GCD+L+ TP L L++ + L ++ LD+A+ ++ E
Sbjct: 168 VQKYSVPIVANGRDLMACAQTGSGKTGGFLFPVLSESFKTGPSPQPESQGSFYQRKAYPTAVIMAPTRELATQIFDEAKKFTYRSWV--------KACVVYGGSPIGNQLREIERGCDLLVATPGRLNDLLERGK-ISLANVKYLVLDEADRMLDMGFE 317
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Match: DBP2 (ATP-dependent RNA helicase of the DEAD-box protein family; has strong preference for dsRNA; interacts with YRA1; required for assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites [Source:SGD;Acc:S000005056]) HSP 1 Score: 52.7582 bits (125), Expect = 3.450e-7 Identity = 82/364 (22.53%), Postives = 152/364 (41.76%), Query Frame = 3
Query: 900 VQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMP-VLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLN--ELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLE-LTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
+ ++R ENE T + +PI ++ L E ++ K IQ P L G + + IA GK++ +P ++ A L+P P+ ++L + + ++ KF S ++R Y G K + + +G +++I TP L+ L E K N + LD+A+ ++ E +++I+ R DR + + + W ++ + D + V LEL+ + Q + D E +L YLE ++ + +T+IFAST + KYL + L + G E + +++E+ R PI++ +D A R D+
Sbjct: 92 IAQFRKENEMT-ISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDK-PTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGD--GPIVLVLAPTRELAVQIQTECSKFGH----SSRIRN---TCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDML---EIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRP---DRQT----LMWSATWPKEVKQLAADYLNDPIQVQVGS-LELSASHNITQIVEVVSDFE--KRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAIH-GDKDQRERDWVLQEFRNGRS----PIMVATDVAARGIDV 426
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Match: PRP28 (RNA binding protein; involved in RNA isomerization at the 5' splice site and for exchange of U6 for U1 snRNA at the 5' splice site; similar to the RNA helicases of the DEAD-box family [Source:SGD;Acc:S000002651]) HSP 1 Score: 51.6026 bits (122), Expect = 9.292e-7 Identity = 65/289 (22.49%), Postives = 125/289 (43.25%), Query Frame = 3
Query: 1047 IQSYMIPNI-----LRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTY---NPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE-TLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKF--SIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEE 1880
IQ IPN+ R F L +A GK++ ++P+L ++ P P A+IL + + V ++ +K T+ I + ++++ G + + +GCD+L+ TP L+ L+ H + ++E LD+A+ +I E + IL A + + TAT+ T +E M +I V E + Q+++EY D + D ++KL + + I IIF + + + ++ ++ + ++ GS S E+
Sbjct: 200 IQRITIPNVCNMKQYRDF--LGVASTGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTK-IWSKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENH-LLVMKQVETLVLDEADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATM-TPVIEKIAAGYMQKPVYATIGVETGSEPLI-----QQVVEYADNDEDKFKKLKPIVAKYDPPI---IIFINYKQTADWLAEKFQKETNMKVTILHGSKSQEQ 475
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Match: DRS1 (Nucleolar DEAD-box protein required for ribosome assembly and function; including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles [Source:SGD;Acc:S000003931]) HSP 1 Score: 48.521 bits (114), Expect = 8.285e-6 Identity = 68/330 (20.61%), Postives = 153/330 (46.36%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPS---QFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQ---KIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDV 2015
IQS IP L G + +A A GK+ ++P+++ + K P++ + I+L + + ++AD ++ RF+ + V N L++ + + D++I TP + ++ F ++ +EI +D+A+ ++ E + L EI+ G PS + + S+++S V + I ++ P + A ++ Q +I + + ++ L L+ L+ T KR ++F + + + + +M + + + GS++ E+ + N+++ + +P+L+ +D A R D I E++++ D+
Sbjct: 257 IQSATIPIALLGKDIIAGAVTGSGKTAAFMIPIIERLLYK---PAKIASTRVIVLLPTRELAIQVADVGKQIARFV---SGITFGLAVGGLN--LRQQEQM-LKSRPDIVIATPGRFIDHIRNSASFNVDSVEILVMDEADRMLEEGFQDELNEIM----------GLLPSNRQNLLFSATMNSKIKSLVSLSLKKPVRIMIDPPKKAAT--KLTQEFVRIRKRDHLKPALLFNLIRKLDPT--GQKRIVVFVARKETAHRL-RIIMGLLGMSVGELHGSLTQEQ---RLDSVNKFKN-LEVPVLICTDLASRGLD--IPKIEVVINYDM 556
BLAST of Tudor domain-containing protein 12 vs. Ensembl Nematostella
Match: EDO36108 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJJ0]) HSP 1 Score: 66.6254 bits (161), Expect = 1.177e-10 Identity = 73/315 (23.17%), Postives = 127/315 (40.32%), Query Frame = 3
Query: 2604 RVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDK------NLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVL-------FYRDQCWHRGYVIKIDCDVKIFS--LDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNL 3503
R +++K + SG +++VK +D G+ D+ +L E +P Q +EC GIR D E + +ES + E+K L A+I +R + V ++D +S L+ K S+ R+ K KP+ ++ P M F+Y+ + + E +C+ + SPS ++ + L L ++I + D LS D + V+ F D CW+R V ++ K+ +D G E+ + +KKL + P Q I C+L
Sbjct: 293 RALITKDLRDASG-FIEVKFMDYGNIQRTPLTDVRELKDEFLSLPAQVVECLHHGIRQADGSEEWPKESLILFKKLTEDKHLVALI-------------DKRNAEGKYEVDLYDTTGDMDMQISQILIAAGYAVKTSEFNPNPLRIPAAKSTPPKPA--PVQVQASPQMPSFSYSKEQL----------NPGQEYKCLITACQSPSKFYIQLFSMASKLEKLMMDIENYYDR---LSADDEWLACPVVGDICCAKFSEDDCWYRAIVTEVQESKKVGVRFIDYGNCESL--PPKHIKKLVPRFSDLPCQGIECSL 576
BLAST of Tudor domain-containing protein 12 vs. Ensembl Nematostella
Match: EDO25716 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVP3]) HSP 1 Score: 55.0694 bits (131), Expect = 3.086e-8 Identity = 39/144 (27.08%), Postives = 73/144 (50.69%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENII 1478
IQ+ IP IL G + +A A GK+ G +P+L+ + S ++ + A+IL + + +++AD + +++ +V + G M+ + +G DVL+ TP LL L Q K ++LE+ LD+A+ ++
Sbjct: 27 IQAQAIPAILAGKDVMAAAQTGTGKTAGFTLPILENLVKG--SRAKPNHVRALILTPTRELAAQVADNIATYGQYLPLRSQV-------VFGGVGINPQMMNLRKGADVLVATPGRLLD-LYQQNAVKFSQLEVLVLDEADRML 160
BLAST of Tudor domain-containing protein 12 vs. Ensembl Nematostella
Match: EDO49247 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGX3]) HSP 1 Score: 49.6766 bits (117), Expect = 9.886e-6 Identity = 74/343 (21.57%), Postives = 144/343 (41.98%), Query Frame = 3
Query: 960 PILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQ-TIATKQLSP-SRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSD 1973
P+ ++K K L A+ K IQ +P +L G + + IA GK++ +P++ ++ ++ P R P +I+ S + + + F+R +++ R GS K + +G +++ TP L+ L + L+ LD+A+ +I E ++ I Y + S+ + + +++++ K + ++ V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G S EE +RE++Q N +L+ +D A + D
Sbjct: 45 PVKTFKEMKFPRPILA-ALKKKGITHPTPIQVQGLPAVLTGRDMIGIAFTGSGKTLVFTLPIIMFSLEQEKAMPFQRNEGPYGMIVVPSRELARQTFEVITHFSR-ALEAHGFPSLRTNLCIGGSSIKEQSDAMKRGVHMVVATPGRLMDLLDKR-IITLDVCRYLVLDEADRMIDMGFEEDVRTIFSYFK-------SQRQTLLFSATMPKKIQNFAKSALVKPVTVNVGRAGAASLDVIQEV-----EYVKQEA----KVVYLLECLQKTPPPVLIFAEKKSDVDDIHEYLLLKG-VEAVAIHGDKSQEERVHAIREFHQG----NKDVLVATDVASKGLD 363
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Match: tdrd12 (tudor domain containing 12 [Source:ZFIN;Acc:ZDB-GENE-121214-348]) HSP 1 Score: 137.502 bits (345), Expect = 5.148e-32 Identity = 150/665 (22.56%), Postives = 282/665 (42.41%), Query Frame = 3
Query: 1056 YMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEIL--IYKRTGAIDRGSEPSQFI-TATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVD--VSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPG-CVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGY--VKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLC 3026
Y P + +G N+ I + + L P+L + L Y P+ ++LC W++V + E+ TR S+ +R + K +P + C +L+ TP + L H L LD+A+ + A + + IL +K T ++ P Q + A W+ +E+ V M SI + P E + V+Q + L+ L+ + S ++T+I A++ D+ +Y+ + K++ LK T + + ++W++ G + IL+ +DE L+C + I +A ++H + + FG RL + + LS + C + + + N R + R+L R + P L + +++ K S +C +K FG C+ C RH +D+ LP G I+ L++ S S F R+ + EF + MA+Y++++ R + G L A++ D RV + + N + V V+ ID G E V+ +L+LP+ +P QA+E V G++P D + + + + + A L +G+T+++D + + + + + N+ +L + +N H+ L LC
Sbjct: 297 YSWPAVAQG-NSTVIISHSSDQPLSFLAPLLSHVLQNSL-----YTPMGLLLCPGWERVQMVFSMLEE-TRV---SESLRPATALLGVGKDEAKNFKLP--KNCRMLVTTPFTAVRLLSCHCRL-FQRLYHLVLDEADQLFARAPDQMTTILQHFHKVTTGEEKALFPQQLVCVAKRWSPHMEAMVAAYMPYP-SIVITIPEEAGLYGNVQQ-------VRQFCGHSLLGVLDFSPLSCQKTLIIANSAQDVEYIYEAVSSKSAFCLK--THEDLTHQFTSVAQQWSKVTGPGSPLILVTTDECLKC--LGITDATCVIHYEFPTAPKGFGRRLFCMFKNFRNLS----QQTQSSSCAARSVLLISEKNSRHIIGVMRYLRRTDALLPPELLAFERGVLKARDEQKTSRPLCSYLKSFGVCRDSSVCPDRHTFSPQLDRSALPAAGIIEVLPLFIKSASVFGGRLIR---KEDREFD------EMVSGMASYYSDKKP----EARELQEGGLYAVQEDDTFHRVKILSLPKNGKSQFFCVYVRFIDVGREKEVKSYQMLKLPESFHSLPEQAVEIIVCGVKPADAETDWHPKVIRTISQKIRGLQHRARAVLSVGNTVFVDPMVRVTQVPGMKTLINEYNIQSEILKTGMGIRNPDHLVLLKALC 919
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Match: ddx4 (DEAD-box helicase 4 [Source:NCBI gene;Acc:100049226]) HSP 1 Score: 56.225 bits (134), Expect = 2.936e-7 Identity = 46/180 (25.56%), Postives = 86/180 (47.78%), Query Frame = 3
Query: 963 ILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLE 1493
I++++ KL + LK +S+ +Q Y +P I G + +A A GK+ L+P+LQ + ++ SR P A+I+ + + ++++ A KF+ RP +V Y G M + +GC+VL TP LL + + + L+++ LD+A+ ++ E
Sbjct: 180 IMTFEEAKLCES-LKNNISRSGYVKPTPVQKYGLPIISAGRDLMACAQTGSGKTAAFLLPILQQLMADGVAASRFSEIQEPEAVIVAPTRELINQIYQEARKFS-----FGTCVRPVVV--YGGVNTGYQMREIEKGCNVLCGTPGRLLDMIGRGK-VGLSKVRHLVLDEADRMLDMGFE 350
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Match: ddx4 (DEAD-box helicase 4 [Source:NCBI gene;Acc:100049226]) HSP 1 Score: 55.4546 bits (132), Expect = 5.686e-7 Identity = 45/175 (25.71%), Postives = 85/175 (48.57%), Query Frame = 3
Query: 963 ILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSR---TYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENII 1478
I++++ KL + LK +S+ +Q Y +P I G + +A A GK+ L+P+LQ + ++ SR P A+I+ + + ++++ A KF+ RP +V Y G M + +GC+VL TP LL + + + L+++ LD+A+ ++
Sbjct: 290 IMTFEEAKLCES-LKNNISRSGYVKPTPVQKYGLPIISAGRDLMACAQTGSGKTAAFLLPILQQLMADGVAASRFSEIQEPEAVIVAPTRELINQIYQEARKFS-----FGTCVRPVVV--YGGVNTGYQMREIEKGCNVLCGTPGRLLDMIGRGK-VGLSKVRHLVLDEADRML 455
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Match: DDX41 (DEAD-box helicase 41 [Source:NCBI gene;Acc:101175087]) HSP 1 Score: 53.1434 bits (126), Expect = 2.471e-6 Identity = 79/357 (22.13%), Postives = 143/357 (40.06%), Query Frame = 3
Query: 894 WTVQKY-------RTENETTDFNYL----GSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTI--ATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVN--DPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYR 1916
W +Y R E F+ L G PI S++ K LK + K IQ IP +L G + + IA GK++ +P++ K+L + P +I+C S + + E + + +++ + + R G K M V G +++ TP L+ L Q + L+ LD+A+ +I E ++ I Y +G + +AT+ +++++ K + +I V L VI+ V EY E K+V LE + + +IFA D+ +++YL+ K V+ + G EE + + + +
Sbjct: 138 WKAPRYILNMPETRHERVRKKFHILVDGDGIPAPIKSFREMKFPPAILK-GLKKKGIVHPTPIQIQGIPTVLSGRDMIGIAFTGSGKTLVFTLPIIMFALEQEKRLPFFKREGPYGLIICPSRELARQTHSIIEYYCK-LLEEEGAPQLRTALCIGGMSVKEQMEVVKHGVHMMVATPGRLMDLL-QKKMVSLDICRYLALDEADRMIDMGFEEDIRTIFSYF------KGQRQTLLFSATM-PKKIQNFAKSALVKPVTINVGRAGAASLDVIQEV-----EYVKEEA----KMVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKG-VEAVAIHGGKDQEERTKAIEAFKEGK 474
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Match: ddx42 (DEAD-box helicase 42 [Source:NCBI gene;Acc:101174023]) HSP 1 Score: 51.9878 bits (123), Expect = 6.765e-6 Identity = 68/340 (20.00%), Postives = 138/340 (40.59%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVL-QTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENI-----------IAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLEL-AVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI----LIYNAEIILHVDV 2015
IQ +P L G + + IA GK+ + P+L + K+L P P+A+I+C + + ++ ++F K R VA Y G + +G ++++ TP L+ +K+ + L + D+A+ + IA H+ ++ L++ T + ++E + + D + D E + +V + ++ D L ++LV + +S +IF + + + L Q+ L ++ G M E N ++ ++ + N+PIL+ +D A R DI + N ++ +D
Sbjct: 299 IQCQGVPIALSGRDMIGIAKTGSGKTAAFIWPMLVHIMDQKELEPGE--GPIAVIVCPTRELCQQIHAECKRFG-------KAYSLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATSLQRVTYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSAT-----------------FRKKIERLARDILVDPIRVVQGDIGEANEDVTQVVEILLSGSDKWAWLTRRLVEF-----TSAGSVLIFVTKKANSDELAANLTQEG-YSLGLLHGDMDQSERNKVISDFKKK----NLPILVATDVAARGLDIPSIRTVVNYDVARDIDT 601
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Match: SMESG000065057.1 (SMESG000065057.1) HSP 1 Score: 3419.4 bits (8865), Expect = 0.000e+0 Identity = 1697/1697 (100.00%), Postives = 1697/1697 (100.00%), Query Frame = 3
Query: 3 MVKFQVIKVEQPNCFVGKDLELFATINSSCQELRQSNSKILPCSEVVIQKIYLANLITEIVRIRVLQCINSNTFRCLLIDHGRIEEIRKQKIYNIPLNKLDMDPAVKMIKIPGVRPAGMNDVLNGPMITVHLSESDKWMPASFKFVSRIFEENSVIHVKYLKQVSKDKVFVDVLVNYLNQRENLKNLLVAQGYAFISKEHDIDIMENHLNHVCINEKETHKSATDKFDSVSIDSLENESISIVIEKMKGDDQMNSTEPNTTYQLNYWKTPENSSGNQSIHGTLDELSLDIINLKVKCWTVQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVLFYRDQCWHRGYVIKIDCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSDDVIAAIKHYAIGTDKNTSLIISVYKEENVDSKMFGDSEIFSQLNDDELFLFLKRYXXXXXXXXXXXXDRMLHYVLIRNQHILPSLTWIHDVLPESRPFSSRLERNGSIPHLSADILSTKDGAKRLRISQTIERIIENKIKSYEASGSINENMASFIHGLTILIHFMNEKSEFMCIYRSINRLLSLAYKTIPMSNVENENERFTIKSITTLMLSYESFIFHMLRHLEITARTHPIDNCHVILDNLRMILLDPFTVTVLFEEPSWYVVMATCVASLQNDCNHYNLLMDILVQLVMLWKSNKTVLGDILIHCCLSLQKSDSPVIWTASLALITCFVNKQNYASIFRNIKFFEILFDKFVSYYEQIDRWEEFHENALDILSNMWRNGSANSREILRRRILSTDIDVVCRKNPRNTTLSRLLTEILREESCNSSHDDTVRAPTISKNAPDKDAIDWIEGREFIEKKHRSSYKRIYYGXXXXXXXXXXXXXXXXXXXXXVGATPFLKDDLNPADEDNVLCFVKP 5093
MVKFQVIKVEQPNCFVGKDLELFATINSSCQELRQSNSKILPCSEVVIQKIYLANLITEIVRIRVLQCINSNTFRCLLIDHGRIEEIRKQKIYNIPLNKLDMDPAVKMIKIPGVRPAGMNDVLNGPMITVHLSESDKWMPASFKFVSRIFEENSVIHVKYLKQVSKDKVFVDVLVNYLNQRENLKNLLVAQGYAFISKEHDIDIMENHLNHVCINEKETHKSATDKFDSVSIDSLENESISIVIEKMKGDDQMNSTEPNTTYQLNYWKTPENSSGNQSIHGTLDELSLDIINLKVKCWTVQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVLFYRDQCWHRGYVIKIDCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSDDVIAAIKHYAIGTDKNTSLIISVYKEENVDSKMFGDSEIFSQLNDDELFLFLKRYSVTVSKPSVKPSDRMLHYVLIRNQHILPSLTWIHDVLPESRPFSSRLERNGSIPHLSADILSTKDGAKRLRISQTIERIIENKIKSYEASGSINENMASFIHGLTILIHFMNEKSEFMCIYRSINRLLSLAYKTIPMSNVENENERFTIKSITTLMLSYESFIFHMLRHLEITARTHPIDNCHVILDNLRMILLDPFTVTVLFEEPSWYVVMATCVASLQNDCNHYNLLMDILVQLVMLWKSNKTVLGDILIHCCLSLQKSDSPVIWTASLALITCFVNKQNYASIFRNIKFFEILFDKFVSYYEQIDRWEEFHENALDILSNMWRNGSANSREILRRRILSTDIDVVCRKNPRNTTLSRLLTEILREESCNSSHDDTVRAPTISKNAPDKDAIDWIEGREFIEKKHRSSYKRIYYGSSTESSSNDHSNSEADSDSSDVGATPFLKDDLNPADEDNVLCFVKP
Sbjct: 1 MVKFQVIKVEQPNCFVGKDLELFATINSSCQELRQSNSKILPCSEVVIQKIYLANLITEIVRIRVLQCINSNTFRCLLIDHGRIEEIRKQKIYNIPLNKLDMDPAVKMIKIPGVRPAGMNDVLNGPMITVHLSESDKWMPASFKFVSRIFEENSVIHVKYLKQVSKDKVFVDVLVNYLNQRENLKNLLVAQGYAFISKEHDIDIMENHLNHVCINEKETHKSATDKFDSVSIDSLENESISIVIEKMKGDDQMNSTEPNTTYQLNYWKTPENSSGNQSIHGTLDELSLDIINLKVKCWTVQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDILIYNAEIILHVDVSEPSFGNRLNFLRDKYAKLSFLKSRNEPIEKCHSFIFICPTTLNLRSANFLHRFLGRCGSDRPEWLKEKSIDFILNKEKSKGSNEICPRIKCFGECKLPGCVKRHMVLSDIDKPLLPNKGHIQFRLLYLVSPSHFFVRINEFSGNSEAEFPYSSQYLSLKMKMANYFNNQMNIHGVNLRLVHVGLLAAIKIKDLLERVVVSKMKSNQSGGYVKVKLIDKGSEMIVEQADLLQLPKELGEIPPQAIECYVTGIRPIDNDEIYSEESCLFTNTFLEEKDLYAIIRLCIGSTLWIDSVTQRIHHAQTRVTVFDKNLSVTLLDKNLVDKNSQHIEKLARLCTGKIDIWKPSLEESTIEHVPIMRKFTYTNNPIVFEALPVLDDDNQLETECVFSHIFSPSLIFLNNKTTIKSLRDLQLEINSLIDSIEALSISDIKIGSKVLFYRDQCWHRGYVIKIDCDVKIFSLDEGLIENYDHSREQLKKLPYEYQQTPYQAILCNLFFCSHLNNSYSDDVIAAIKHYAIGTDKNTSLIISVYKEENVDSKMFGDSEIFSQLNDDELFLFLKRYSVTVSKPSVKPSDRMLHYVLIRNQHILPSLTWIHDVLPESRPFSSRLERNGSIPHLSADILSTKDGAKRLRISQTIERIIENKIKSYEASGSINENMASFIHGLTILIHFMNEKSEFMCIYRSINRLLSLAYKTIPMSNVENENERFTIKSITTLMLSYESFIFHMLRHLEITARTHPIDNCHVILDNLRMILLDPFTVTVLFEEPSWYVVMATCVASLQNDCNHYNLLMDILVQLVMLWKSNKTVLGDILIHCCLSLQKSDSPVIWTASLALITCFVNKQNYASIFRNIKFFEILFDKFVSYYEQIDRWEEFHENALDILSNMWRNGSANSREILRRRILSTDIDVVCRKNPRNTTLSRLLTEILREESCNSSHDDTVRAPTISKNAPDKDAIDWIEGREFIEKKHRSSYKRIYYGSSTESSSNDHSNSEADSDSSDVGATPFLKDDLNPADEDNVLCFVKP 1697
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Match: SMESG000072404.1 (SMESG000072404.1) HSP 1 Score: 65.4698 bits (158), Expect = 2.532e-10 Identity = 69/292 (23.63%), Postives = 133/292 (45.55%), Query Frame = 3
Query: 933 DF-NYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRI-VAAYNGSLKKMTMIPVLQ-GCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEH-LETLQEILIYKRTGAIDRGSEPSQ--FITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFAST 1790
DF N L + S+ + K+ LK M + TK IQ IP L+ + A A GK++ L+P+++ + R P A++L + + ++ + A+ +F P++ V +G L + L+ G D++I TP L+ + F L ++E F LD+A+ ++ E+ +E ++E+L +G P++ + + T ++ + + D F I VN ++A + ++Q++I + + ++ L + KRTIIF T
Sbjct: 86 DFKNILTEYVTVASFMDMKISKPILKALMDSNITK-PTPIQEACIPIGLKNKDICACAKTGSGKTLAFLIPIVEKLIRSPNQQGRYTVPRAVVLSPTRELALQIYEVAKMLIKF--------SPKLSVQLVSGGLNRSNQEACLRNGADIIIATPGRLIDIIHNTPNFDLLKIEFFILDEADKMLDEYFIEQIKEVL---------KGCSPTRQVMLFSATMTENVKDLISLSLKDPFKIFVNQNNDVA--DNLQQEVIRIRSHRAEDREAMLMAL-ICRGFSKRTIIFLPT 356
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Match: SMESG000049071.1 (SMESG000049071.1) HSP 1 Score: 58.5362 bits (140), Expect = 3.624e-8 Identity = 61/265 (23.02%), Postives = 126/265 (47.55%), Query Frame = 3
Query: 999 FLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIA-TKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEH--LETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLE-LTESSIKRTIIF 1781
FL+ + D K L +Q Y IP I G + +A A GK+M L+P+++ I+ S S +P +I+ + + ++ A + + DS + +Y G + +M+ + + CD+L+ TP L++ L+ L+++ LD+A+ ++ +E+++ L+Y+++ + +AT + + ++ + + D +AV L A +KQ +++ + KL A LE LT + +T++F
Sbjct: 131 FLRLNIKSSDYKKLTPVQKYTIPMINSGRDLMACAQTGSGKTMAFLVPIIKNISENPDTSSSGKNSPKCLIVVPTRELCRQIFTVAHRLCK---DS----SVKCSYSYGGVEMRTSMMKLYK-CDILVSTPGRLVANLESAA-ISLDKIRYLVLDEADRLLQNEKFMESIK--LVYEKSKLVGVDKFHVSMFSAT-FPAEIQQLGESLLSDHLFVAVG--LVGAANTDIKQTVLQVNS-----HDKLNASLEYLTNNKTGKTLVF 376
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Match: SMESG000012031.1 (SMESG000012031.1) HSP 1 Score: 52.7582 bits (125), Expect = 1.760e-6 Identity = 80/361 (22.16%), Postives = 160/361 (44.32%), Query Frame = 3
Query: 900 VQKYRTENETTDFNYLGSVRPILSYKNDKLLATFLKEAMSKHDTKFLLIIQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYN-PLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLET-LQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYLELTESSIKRTIIFASTDDDILLVYKYLMQKASVDLKMMTGSMSPEELNLMVREWNQYRGYVNMPILLISDEALRCSDI 1976
V+K+R EN T P+L ++ + F+ A+ + IQS P L G + + IA GK+ L+P + I + P ++ + P+ +IL + ELA EK I+ + + +I Y G+ + + + + +V+I TP L+ +L + L LD+A+ ++ E +++I+ R DR + + + W + +++ + + I V L L +KQK+ ++ E + ++L+ L ++ KR+++F+ T + + + +++K +D M G E +++++ R YV L+ +D A R DI
Sbjct: 56 VEKFRKENNITIIGE-NVPNPVLCFEEVQF-PNFIMNAIKDNRWIKPTAIQSQGWPMALSGSDVVGIAQTGSGKTASFLLPAIVHIEAQ--PPVQSGDGPICLILVPT----RELAQQVEKVA---IEFSEYAKIKIACCYGGASRNSQIHQLNKNPEVVIATPGRLIDFL-NDKITNLRRCTYLVLDEADRMLDMGFEPDIRKIVSQVRP---DRQT----LMWSATWPNEVQNLASDFLKNYVQINVGS-LYLHANPDIKQKVEILDEKEKE--ERLIEI--LCDNKRKRSLVFSETKRKVDDLCRIIVRKG-IDCMAMHGDKVQREREKVLQDFRDGRCYV----LIATDVASRGLDI 387
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Match: SMESG000011907.1 (SMESG000011907.1) HSP 1 Score: 51.9878 bits (123), Expect = 4.724e-6 Identity = 54/232 (23.28%), Postives = 98/232 (42.24%), Query Frame = 3
Query: 1047 IQSYMIPNILRGFNTLAIAPPRKGKSMGLLMPVLQTIATKQLSPSRTYNPLAIILCSSWKKVSELADAAEKFTRFIIDSDKVRRPRIVAAYNGSLKKMTMIPVLQGCDVLIITPNCLLSWLKQHEFFKLNELEIFCLDDAENIIAEHLETLQEILIYKRTGAIDRGSEPSQFITATVWTSRLESYVKHEMGDKFSIAVNDPLELAVIERVKQKIIEYEDIEGDLYQKLVAYL 1742
IQ P ++ G + + IA GK++ L+P I + + P +IL + + ++ + +K+T IDS V Y G+ K+ + + + ++++ TP + LK L ++ LD+A+ ++ E LIY A+ R + +T+ W ++ M + + V L+L VKQ +EY D D Q+LV L
Sbjct: 382 IQCIAWPILMTGRDLIGIAQTGTGKTLAFLLPAFIHIEGQPKPREKRQGPTVLILSPTRELAIQIQNEVQKYTYHDIDS--------VVCYGGADKRDQIYQLKENPEIVVGTPGRIQD-LKDSGVLNLKDVSYLVLDEADRMLDMGFEIQVVNLIY----AVRRQRQ--TVMTSATWPFGVQRIALTHMKNPVQVNVG-TLDLNACHTVKQH-VEYVDYH-DKTQRLVEIL 595 The following BLAST results are available for this feature:
BLAST of Tudor domain-containing protein 12 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Tudor domain-containing protein 12 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Tudor domain-containing protein 12 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Tudor domain-containing protein 12 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Tudor domain-containing protein 12 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001485 ID=SMED30001485|Name=Tudor domain-containing protein 12|organism=Schmidtea mediterranea sexual|type=transcript|length=5107bpback to top protein sequence of SMED30001485-orf-1 >SMED30001485-orf-1 ID=SMED30001485-orf-1|Name=SMED30001485-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1698bp MVKFQVIKVEQPNCFVGKDLELFATINSSCQELRQSNSKILPCSEVVIQKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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