Lysine-specific demethylase

Overview
NameLysine-specific demethylase
Smed IDSMED30001441
Length (bp)4454
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Lysine-specific demethylase (SMED30001441) t-SNE clustered cells

Violin plots show distribution of expression levels for Lysine-specific demethylase (SMED30001441) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Lysine-specific demethylase (SMED30001441) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Lysine-specific demethylase (SMED30001441) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001441

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30001441h1SMcG0011597 SmedASXL_014435SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30001441h1SMcG0011597 SmedASXL_014435SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30001441h1SMcG0011597 Contig53564newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30001441h1SMcG0011597 Contig53564uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
nervous systemSMED30001441h1SMcG0011597 dd_Smed_v4_3334_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001441h1SMcG0011597 dd_Smed_v4_3334_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001441h1SMcG0011597 dd_Smed_v4_15120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001441h1SMcG0011597 dd_Smed_v4_15120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001441h1SMcG0011597 dd_Smed_v4_3334_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30001441h1SMcG0011597 dd_Smed_v4_15120_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001441h1SMcG0011597 SMED_29032_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30001441h1SMcG0011597 SMED_29032_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Human
Match: KDM5A (lysine demethylase 5A [Source:HGNC Symbol;Acc:HGNC:9886])

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 370/865 (42.77%), Postives = 503/865 (58.15%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIM---------------LSADHDSNIYISQSTVKPKPV----LHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLV-------------------SGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQN 2577
            FV PPECPVF P+ EEF DPL +I +IRP+A K+GIC+I PP DW PPF+  V +F+FTPRVQ+L ELEA +R++L+F+ +L++F  LQGS  LKIP +  + +DLY L K+V   GG++ +   K W K+ +++GY       SL ++HYE+I+ PY++                L    +  +  + +   P+P     + P  T++ K+ QS+  D S    + ELK+LQ  GAGP++          ED++                     G L    +  YVC  CG G+ EDKLL+CD   C D YH  CL PPL  VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP    +K+G   R    P  +   +Y+   WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR+ APELF++  DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL +GR CV HY +L RHCVFSH+EL+                              M++   CLD  +   V  EL L+ EEE + R  + +M +   E+ +FE + DDER C  C+TTCFLSA  C C  E               R+VCL H  ++C  CP+ +    YR+ LE++  LL G++VR Q + +W + +    TE   + +AN   K+  L +L++ L +  +  +   + F K R  ++  +   +V +  L   Q 
Sbjct:   13 FVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGS-TLKIPVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKT-QSESGDVS---RNTELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDG--CDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFP----VKDG---RRKILPEEE---EYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELI----------------------------FKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPE---------------RLVCLYHPTDLC-PCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRV----TE---ALSANFNHKK-DLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQK 807
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Human
Match: KDM5C (lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114])

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 372/871 (42.71%), Postives = 507/871 (58.21%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSA----------DHDS--------NIYISQSTVKPKPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCE 2493
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++  S           D++         +I + QS    +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVCNTRPFDNEEKDKEYKPHSIPLRQSV---QPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE 809
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Human
Match: KDM5C (lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114])

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 370/874 (42.33%), Postives = 504/874 (57.67%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCE 2493
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE 810
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Human
Match: KDM5C (lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114])

HSP 1 Score: 670.233 bits (1728), Expect = 0.000e+0
Identity = 370/874 (42.33%), Postives = 504/874 (57.67%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCE 2493
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE 810
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Human
Match: KDM5D (lysine demethylase 5D [Source:HGNC Symbol;Acc:HGNC:11115])

HSP 1 Score: 665.226 bits (1715), Expect = 0.000e+0
Identity = 357/819 (43.59%), Postives = 481/819 (58.73%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLS-ADH-DSNIYISQSTVKPK--------------PVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA----------------------STKDEVKLEDDLVSGPLKR---------------------KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIK 2373
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPRVQ+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  + +DLY L K+V E GGY+ I  ++ W ++A ++ Y       S LR+HYE+II PY++  S A+H   N +   + VK K              P    S +++ K LQ DP   E  +E   ELK+LQ  G GP++                        + KDE     ++ S  LK+                     + +  Y+C+ C  GD++DKLL CD   C D YH  CL PPL ++P+  W+C  C+L    + P  +GF  ++  Y+L  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP    + N K    N  P      +Y+   WNLN++P+  +SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+   PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C                             M++    LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L++R + F +W   ++
Sbjct:    8 FLPPPECPVFEPSWAEFQDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRVQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERKILDLYSLSKIVIEEGGYEAICKDRRWARVAQRLHYPPGKNIGSLLRSHYERIIYPYEMFQSGANHVQCNTHPFDNEVKDKEYKPHSIPLRQSVQPSKFSSYSRRAKRLQPDPEPTEEDIEKHPELKKLQIYGPGPKMMGLGLMAKDKDKTVHKKVTCPPTVTVKDEQSGGGNVSSTLLKQHLSLEPCTKTTMQLRKNHSSAQFIDSYICQVCSRGDEDDKLLFCDG--CDDNYHIFCLLPPLPEIPRGIWRCPKCILAECKQPPEAFGFEQATQEYSLQSFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFP----VSNSK---QNLSPEEK---EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELIC----------------------------KMAAFPETLDLNLAVAVHKEMFIMVQEERRLRKALLEKGVTEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPTMLHKLKIRAESFDTWANKVR 768
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Match: rbr-2 (Lysine-specific demethylase rbr-2 [Source:UniProtKB/Swiss-Prot;Acc:Q23541])

HSP 1 Score: 485.723 bits (1249), Expect = 2.254e-146
Identity = 279/793 (35.18%), Postives = 422/793 (53.22%), Query Frame = 1 
Query:   79 EMEEHF--TFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIAT------KMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQST---VKPKPVLHPSTTKKRKSLQSDPIDE--------SLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKC----------LSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLT--KIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWE 2361
            EM + F   FV PP  P++ PT+EEF DP+EY+ +IR  A K G+ +I+PP ++ PPF+++   F F PR QKL E+EA  + K  F+ +L  F R  G       + +G  VDLY+LH++V   GG + +  ++ W  +A       +M     S   +L R+HY   I P++  L      N   S      +K K   H  T +    + +D   E        S+       K  + S +   +  S+K     ++       K+K           +    C  C  G  ED LL+CD + C +  H  C  P L +VP+  W+C  C+    +K  L++GF  +   Y L  F + A+K+K +YFG +    V C +VE+ FW+ + S  + + V+YGAD+ +S  GSGFP  E+   G        P++ L  QY++  WNLN +P+ ++SVL      I GM VPW YVGM FS+FCWH EDHW++S+NY H+GE K WYGV  E+AE+FE A++K AP L     DL HH+TT  NP++L   GVP++   Q AG+FV+TFPRAYHAGFN+G NFAEAVNF P +WLS GR CVE Y+ + R+ VFSHDELL  + EA     D +             G++MS              H EL  + E+++  R  + ++ ++  +++Q +FE + D++R+C  C+TT F+ A  C                 K K++ C+ H +++CNSC   ++ + YRF L++++ +   L  R  +++ W+
Sbjct:   41 EMYDQFYKKFVRPPMAPIYYPTEEEFSDPIEYVAKIRHEAEKFGVVKIVPPANFKPPFAIDKEAFTFRPRTQKLNEVEAIVKEKHTFIDRLINFNRYSGLTFEFPVDRDGNIVDLYRLHRIVQNFGGCEEVNEDEKWRDVAREYLPKEQMARGVPSAFINLIRSHYNLHIEPFNRNLKEKAMKNDDESDDEMEELKHKYQHHHGTMRTEIEVPNDKTTEGGEDECPVSMQSGRRRSKNKKASSSRKTLGTSSK-----KNSTRGRKNKKKAEGDDDDDEDPMDQVFCVACNEGKDEDLLLLCDIDGCNNGRHTYCCDPVLDEVPEGEWRCPKCIESEDAKIGLDWGFYDADTEYNLNSFTEFANKWKCDYFGVKDVSQVSCDAVERSFWKNVISHENPVSVKYGADLITSRVGSGFPRKEDKHTG--------PDLKLKQQYASHAWNLNNMPVLRESVLSHFNTGISGMMVPWVYVGMCFSTFCWHTEDHWTYSVNYNHFGERKIWYGVGGEDAEKFEDALKKIAPGLTGRQRDLFHHMTTAANPHLLRSLGVPIHSVHQNAGEFVITFPRAYHAGFNEGLNFAEAVNFAPIDWLSKGRECVESYSNVRRYLVFSHDELLFKMVEA----MDKL-------------GISMS-----------LATHEELIRIYEKQKMLRELLARLGVSNRQMQQVMFEKIPDEQRSCRFCKTTLFMCALVCN----------------KHKKMTCVEHHDHLCNSCTTKDYRYQYRFELDQLNNMCDELGKRTVNYNGWK 776
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Match: rbr-2 (Lysine-specific demethylase rbr-2 [Source:UniProtKB/Swiss-Prot;Acc:Q23541])

HSP 1 Score: 484.567 bits (1246), Expect = 3.958e-146
Identity = 276/784 (35.20%), Postives = 418/784 (53.32%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIAT------KMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQST---VKPKPVLHPSTTKKRKSLQSDPIDE--------SLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKC----------LSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLT--KIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWE 2361
            FV PP  P++ PT+EEF DP+EY+ +IR  A K G+ +I+PP ++ PPF+++   F F PR QKL E+EA  + K  F+ +L  F R  G       + +G  VDLY+LH++V   GG + +  ++ W  +A       +M     S   +L R+HY   I P++  L      N   S      +K K   H  T +    + +D   E        S+       K  + S +   +  S+K     ++       K+K           +    C  C  G  ED LL+CD + C +  H  C  P L +VP+  W+C  C+    +K  L++GF  +   Y L  F + A+K+K +YFG +    V C +VE+ FW+ + S  + + V+YGAD+ +S  GSGFP  E+   G        P++ L  QY++  WNLN +P+ ++SVL      I GM VPW YVGM FS+FCWH EDHW++S+NY H+GE K WYGV  E+AE+FE A++K AP L     DL HH+TT  NP++L   GVP++   Q AG+FV+TFPRAYHAGFN+G NFAEAVNF P +WLS GR CVE Y+ + R+ VFSHDELL  + EA     D +             G++MS              H EL  + E+++  R  + ++ ++  +++Q +FE + D++R+C  C+TT F+ A  C                 K K++ C+ H +++CNSC   ++ + YRF L++++ +   L  R  +++ W+
Sbjct:   17 FVRPPMAPIYYPTEEEFSDPIEYVAKIRHEAEKFGVVKIVPPANFKPPFAIDKEAFTFRPRTQKLNEVEAIVKEKHTFIDRLINFNRYSGLTFEFPVDRDGNIVDLYRLHRIVQNFGGCEEVNEDEKWRDVAREYLPKEQMARGVPSAFINLIRSHYNLHIEPFNRNLKEKAMKNDDESDDEMEELKHKYQHHHGTMRTEIEVPNDKTTEGGEDECPVSMQSGRRRSKNKKASSSRKTLGTSSK-----KNSTRGRKNKKKAEGDDDDDEDPMDQVFCVACNEGKDEDLLLLCDIDGCNNGRHTYCCDPVLDEVPEGEWRCPKCIESEDAKIGLDWGFYDADTEYNLNSFTEFANKWKCDYFGVKDVSQVSCDAVERSFWKNVISHENPVSVKYGADLITSRVGSGFPRKEDKHTG--------PDLKLKQQYASHAWNLNNMPVLRESVLSHFNTGISGMMVPWVYVGMCFSTFCWHTEDHWTYSVNYNHFGERKIWYGVGGEDAEKFEDALKKIAPGLTGRQRDLFHHMTTAANPHLLRSLGVPIHSVHQNAGEFVITFPRAYHAGFNEGLNFAEAVNFAPIDWLSKGRECVESYSNVRRYLVFSHDELLFKMVEA----MDKL-------------GISMS-----------LATHEELIRIYEKQKMLRELLARLGVSNRQMQQVMFEKIPDEQRSCRFCKTTLFMCALVCN----------------KHKKMTCVEHHDHLCNSCTTKDYRYQYRFELDQLNNMCDELGKRTVNYNGWK 743
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Match: jmjd-2 (Lysine-specific demethylase 4 [Source:UniProtKB/Swiss-Prot;Acc:Q9U297])

HSP 1 Score: 124.79 bits (312), Expect = 1.993e-28
Identity = 61/162 (37.65%), Postives = 91/162 (56.17%), Query Frame = 1 
Query: 1321 ELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQ---APELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCV 1797
            E WN+N L     ++L      I G+   + Y GM  ++F WH ED   +SIN+LH+G PK W+ +SSE+A++FE  M +Q     E     +  L H T ++ P +L + G+P     Q+  +F++TFPR YH GFN G+N AE+ NF    W+  G+  V
Sbjct:  227 EEWNMNRL----GTILEDTNYEIKGVNTVYLYFGMYKTTFPWHAEDMDLYSINFLHFGAPKYWFAISSEHADRFERFMSQQFSYQNEYAPQCKAFLRHKTYLVTPELLRQAGIPYATMVQRPNEFIITFPRGYHMGFNLGYNLAESTNFASQRWIDYGKDAV 384
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Match: set-16 (Histone-lysine N-methyltransferase [Source:UniProtKB/TrEMBL;Acc:G5EGI1])

HSP 1 Score: 57.3806 bits (137), Expect = 1.115e-7
Identity = 29/70 (41.43%), Postives = 39/70 (55.71%), Query Frame = 1 
Query:  784 VKLEDDLVSGPLKR--KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNC 987
            V L D L S  + R  +CL   VC+ CG+G  E  LL+CD  EC   YH  C+ P L ++P+  W+C  C
Sbjct:  457 VTLHDKLNSAVVGRGWRCLDCTVCEGCGTGGDEANLLLCD--ECDVSYHIYCMKPLLDKIPQGPWRCQWC 524
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Match: cfi-1 (AT-rich interactive domain-containing protein cfi-1 [Source:UniProtKB/Swiss-Prot;Acc:O02326])

HSP 1 Score: 54.6842 bits (130), Expect = 3.828e-7
Identity = 36/112 (32.14%), Postives = 61/112 (54.46%), Query Frame = 1 
Query:  262 TFQFTPRVQKLYELEAQSRIK------LNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKS--TSQAYSLRTHYEKIILPYD 573
             + +  + ++LYEL    + K      LNFM ++ + V        +IP +  + +DLY+L++LV ++GG   II  KLW +I   +   S  TS A++LRT Y+K +  Y+
Sbjct:  165 AWSYEEQFKQLYELSDDVKRKEWLDDWLNFMHRIGKPV-------TRIPIMAKQVLDLYELYRLVVQHGGLVEIINKKLWREITKGLNLPSSITSAAFTLRTQYQKYLYDYE 269
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0079231)

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 345/813 (42.44%), Postives = 462/813 (56.83%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKST-SQAYSLRTHYEKIILPYDIMLSA--------------------DHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESL------------------METSNELKRLQFS-------GAGPRIYASTKDEVKLEDDLVSGP--LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            +K+     E F F +PPECPVFRPT EEFK+PL YI +IR IA K GI +I+PP  W+PPF+V+V+  +F PRVQ+L ELEA++R+KLNF+ ++++F  LQGS  LKIP +  + +DLY LH++V E GG +    ++ W K+A +M Y S+ S   +L+ HYE+I+ P+++  S                     D     Y +      + +  P+ T  R+S +    + S                    ET  E KR   S       G  P    +T +           P  L    L  Y+C  C  GD E+ +L+CD   C D YH  CL PPL+ +PK  W C  CV+E +SK    +GF  +   YTL +FG+ AD+FK  YF K +H LVP   VE+EFWRI+ S ++D+ VEYGAD+H+   GSGFPT  ++             +    +Y+   WNLN LP+ + S+L  I  +I GM  PW YVGM F++FCWH EDHWS+SINYLHWGEPKTWYGV    AEQFE  M++ APELF +  DLLH + TIMNPNILM   VPV+RTDQ AG+FV+TFPRAYHAGFNQG+NFAEAVNF PA+WL MGR CV HY+ L R CVFSHDEL+C +A    LE         P K               L   I    + ++  +V+ E++ R  + +  +T+ E+  FE + DDER C  C TTCFLSA  C+C N++L              IVCLRH   +C   P  + T +YR+TL+EM  +L  L+V+   F  W
Sbjct:  143 NKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS-LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDG--CDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH-LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYL-----------LPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMA----LE---------PAK---------------LTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACEC-NDKL--------------IVCLRHYTVLCGCAP-EKHTLIYRYTLDEMPLMLQKLKVKAHSFERW 896
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0079232)

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 345/813 (42.44%), Postives = 462/813 (56.83%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKST-SQAYSLRTHYEKIILPYDIMLSA--------------------DHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESL------------------METSNELKRLQFS-------GAGPRIYASTKDEVKLEDDLVSGP--LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            +K+     E F F +PPECPVFRPT EEFK+PL YI +IR IA K GI +I+PP  W+PPF+V+V+  +F PRVQ+L ELEA++R+KLNF+ ++++F  LQGS  LKIP +  + +DLY LH++V E GG +    ++ W K+A +M Y S+ S   +L+ HYE+I+ P+++  S                     D     Y +      + +  P+ T  R+S +    + S                    ET  E KR   S       G  P    +T +           P  L    L  Y+C  C  GD E+ +L+CD   C D YH  CL PPL+ +PK  W C  CV+E +SK    +GF  +   YTL +FG+ AD+FK  YF K +H LVP   VE+EFWRI+ S ++D+ VEYGAD+H+   GSGFPT  ++             +    +Y+   WNLN LP+ + S+L  I  +I GM  PW YVGM F++FCWH EDHWS+SINYLHWGEPKTWYGV    AEQFE  M++ APELF +  DLLH + TIMNPNILM   VPV+RTDQ AG+FV+TFPRAYHAGFNQG+NFAEAVNF PA+WL MGR CV HY+ L R CVFSHDEL+C +A    LE         P K               L   I    + ++  +V+ E++ R  + +  +T+ E+  FE + DDER C  C TTCFLSA  C+C N++L              IVCLRH   +C   P  + T +YR+TL+EM  +L  L+V+   F  W
Sbjct:  143 NKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS-LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDG--CDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH-LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYL-----------LPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMA----LE---------PAK---------------LTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACEC-NDKL--------------IVCLRHYTVLCGCAP-EKHTLIYRYTLDEMPLMLQKLKVKAHSFERW 896
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0307070)

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 345/813 (42.44%), Postives = 462/813 (56.83%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKST-SQAYSLRTHYEKIILPYDIMLSA--------------------DHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESL------------------METSNELKRLQFS-------GAGPRIYASTKDEVKLEDDLVSGP--LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            +K+     E F F +PPECPVFRPT EEFK+PL YI +IR IA K GI +I+PP  W+PPF+V+V+  +F PRVQ+L ELEA++R+KLNF+ ++++F  LQGS  LKIP +  + +DLY LH++V E GG +    ++ W K+A +M Y S+ S   +L+ HYE+I+ P+++  S                     D     Y +      + +  P+ T  R+S +    + S                    ET  E KR   S       G  P    +T +           P  L    L  Y+C  C  GD E+ +L+CD   C D YH  CL PPL+ +PK  W C  CV+E +SK    +GF  +   YTL +FG+ AD+FK  YF K +H LVP   VE+EFWRI+ S ++D+ VEYGAD+H+   GSGFPT  ++             +    +Y+   WNLN LP+ + S+L  I  +I GM  PW YVGM F++FCWH EDHWS+SINYLHWGEPKTWYGV    AEQFE  M++ APELF +  DLLH + TIMNPNILM   VPV+RTDQ AG+FV+TFPRAYHAGFNQG+NFAEAVNF PA+WL MGR CV HY+ L R CVFSHDEL+C +A    LE         P K               L   I    + ++  +V+ E++ R  + +  +T+ E+  FE + DDER C  C TTCFLSA  C+C N++L              IVCLRH   +C   P  + T +YR+TL+EM  +L  L+V+   F  W
Sbjct:  143 NKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS-LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDG--CDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH-LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYL-----------LPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMA----LE---------PAK---------------LTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACEC-NDKL--------------IVCLRHYTVLCGCAP-EKHTLIYRYTLDEMPLMLQKLKVKAHSFERW 896
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0345336)

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 345/813 (42.44%), Postives = 462/813 (56.83%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKST-SQAYSLRTHYEKIILPYDIMLSA--------------------DHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESL------------------METSNELKRLQFS-------GAGPRIYASTKDEVKLEDDLVSGP--LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            +K+     E F F +PPECPVFRPT EEFK+PL YI +IR IA K GI +I+PP  W+PPF+V+V+  +F PRVQ+L ELEA++R+KLNF+ ++++F  LQGS  LKIP +  + +DLY LH++V E GG +    ++ W K+A +M Y S+ S   +L+ HYE+I+ P+++  S                     D     Y +      + +  P+ T  R+S +    + S                    ET  E KR   S       G  P    +T +           P  L    L  Y+C  C  GD E+ +L+CD   C D YH  CL PPL+ +PK  W C  CV+E +SK    +GF  +   YTL +FG+ AD+FK  YF K +H LVP   VE+EFWRI+ S ++D+ VEYGAD+H+   GSGFPT  ++             +    +Y+   WNLN LP+ + S+L  I  +I GM  PW YVGM F++FCWH EDHWS+SINYLHWGEPKTWYGV    AEQFE  M++ APELF +  DLLH + TIMNPNILM   VPV+RTDQ AG+FV+TFPRAYHAGFNQG+NFAEAVNF PA+WL MGR CV HY+ L R CVFSHDEL+C +A    LE         P K               L   I    + ++  +V+ E++ R  + +  +T+ E+  FE + DDER C  C TTCFLSA  C+C N++L              IVCLRH   +C   P  + T +YR+TL+EM  +L  L+V+   F  W
Sbjct:  143 NKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS-LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDG--CDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH-LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYL-----------LPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMA----LE---------PAK---------------LTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACEC-NDKL--------------IVCLRHYTVLCGCAP-EKHTLIYRYTLDEMPLMLQKLKVKAHSFERW 896
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Fly
Match: lid (gene:FBgn0031759 transcript:FBtr0307071)

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 345/813 (42.44%), Postives = 462/813 (56.83%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKST-SQAYSLRTHYEKIILPYDIMLSA--------------------DHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESL------------------METSNELKRLQFS-------GAGPRIYASTKDEVKLEDDLVSGP--LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            +K+     E F F +PPECPVFRPT EEFK+PL YI +IR IA K GI +I+PP  W+PPF+V+V+  +F PRVQ+L ELEA++R+KLNF+ ++++F  LQGS  LKIP +  + +DLY LH++V E GG +    ++ W K+A +M Y S+ S   +L+ HYE+I+ P+++  S                     D     Y +      + +  P+ T  R+S +    + S                    ET  E KR   S       G  P    +T +           P  L    L  Y+C  C  GD E+ +L+CD   C D YH  CL PPL+ +PK  W C  CV+E +SK    +GF  +   YTL +FG+ AD+FK  YF K +H LVP   VE+EFWRI+ S ++D+ VEYGAD+H+   GSGFPT  ++             +    +Y+   WNLN LP+ + S+L  I  +I GM  PW YVGM F++FCWH EDHWS+SINYLHWGEPKTWYGV    AEQFE  M++ APELF +  DLLH + TIMNPNILM   VPV+RTDQ AG+FV+TFPRAYHAGFNQG+NFAEAVNF PA+WL MGR CV HY+ L R CVFSHDEL+C +A    LE         P K               L   I    + ++  +V+ E++ R  + +  +T+ E+  FE + DDER C  C TTCFLSA  C+C N++L              IVCLRH   +C   P  + T +YR+TL+EM  +L  L+V+   F  W
Sbjct:  143 NKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSS-LKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIAPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTETKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDG--CDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVH-LVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYL-----------LPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMA----LE---------PAK---------------LTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAERRAFELVNDDERHCQECNTTCFLSAVACEC-NDKL--------------IVCLRHYTVLCGCAP-EKHTLIYRYTLDEMPLMLQKLKVKAHSFERW 896
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Match: kdm5bb (lysine (K)-specific demethylase 5Bb [Source:NCBI gene;Acc:415256])

HSP 1 Score: 631.328 bits (1627), Expect = 0.000e+0
Identity = 335/800 (41.88%), Postives = 461/800 (57.63%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSA------------------DHDSNIYISQSTV--KPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSD----------------------YVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F  PPECPVF P+ EEFKDP  +I +IRPIA K+GIC++ PP DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV + GG+D +   + W KIA  MG+       S LR HYE+I+ PY++  S                   ++  +  + +  V  +P     P+   KR   +S  I     E       L+       +    K E+ ++  +   P++ K L+                       YVC  CG G+ ED+LL+CD   C D YH  CL PPL+ VPK  W+C  C+ +   K    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    IK G   R    P+ +  +Q     WNLN + +   SVL  +  +I GM +PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELFD+  DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPR+YH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY QLHR+CVFSHDE++C                            NM+    CLD  +   V  +++L+++EER+ R K+ KM + + E   ++ L DDER C  C+TTC+LSA  C C               +    VCL H +++C SCPIS +T  YRFTL+++  +++ +  R + +  W + +
Sbjct:    9 FTPPPECPVFEPSWEEFKDPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWDLQGC-TLKIPHVERKILDLYQLNKLVADEGGFDLVCRERRWTKIAMTMGFAPGKAVGSHLRAHYERILYPYNLFQSGTNLLCLQKPGDEVNDIDKEYKPHDLLQRQNVPLQPSNTSAPARRAKRMKTESGCIKSEEGEGVENKPNLRRRMGSFVVKTEQKKEIPIQ--VKEEPVEIKELNPEPEKSKPKKKNIPPPPVSMVDLYVCLVCGKGNDEDRLLLCDG--CDDSYHTFCLIPPLTDVPKGDWRCPKCLTQECCKPQEAFGFEQAHRDYTLKAFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVGTIQEDVTVEYGADIASKEFGSGFP----IKGG---RFKIAPHDEKYLQCG---WNLNNMAMMTPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAPELFDSQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRSYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRQLHRYCVFSHDEMVC----------------------------NMAMKADCLDVVLASAVQKDMQLMIKEERELREKVRKMGVAQCELFQYDLLADDERQCVKCRTTCYLSALTCPC---------------RPGVQVCLYHTHDLC-SCPISNYTLNYRFTLDDLYPMMNAVRQRAEYYDDWASRV 748
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Match: kdm5ba (lysine (K)-specific demethylase 5Ba [Source:ZFIN;Acc:ZDB-GENE-030131-5379])

HSP 1 Score: 624.394 bits (1609), Expect = 0.000e+0
Identity = 328/781 (42.00%), Postives = 456/781 (58.39%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIM-------------LSADHDSNIY-----ISQSTVKPKPVLHPSTTKKR---KSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPL--KRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F+ PPECPVF P+ EEF DP  +I +IRPIA  +GIC+I PP  W PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DL+ L+KLV E+GG+D +   + W +IA KMG+       S LR HYE+I+ PY +              L+ D     Y       + +V+P      +   KR   +  +S+P  E      N  +R+    A P         V+++++ +  P+  ++  +  Y+C  CG G  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +   K  + +GF  +   YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +KNG    +  E        Y    WNLN +P+ + SVL  +  +I GMK+PW YVGM FSSFCWHIEDHWS+S+NYLHWGEPKTWYG     AEQ E  M+  APELF++  DLLH + TIMNPN+LM+ GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC A+WL +GR CVEHY  L+R+CVFSHDE+ C IA  A                         S ++ L   +++ ++A    +++EE+  R K  K+ +   +Q  ++ L D+ER C  C+TTC+LSA  C C  E+               +VCL H  ++C SCP   +T  Y++TL E+      L  R + +  W + +
Sbjct:    9 FIPPPECPVFEPSWEEFADPFGFINKIRPIAENTGICKIRPPPGWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKTLDLFVLYKLVKEDGGFDVVCKERRWTQIALKMGFAPGKAIGSHLRAHYERILYPYYLFQTGANLMNSQKPTLTNDTKDKEYKPHDLPQRQSVQPVETCTIARRAKRTEGRCFKSEP-GEVCENKPNLRRRMGSYVAKPEPGTFKMLPVQVKEEPIVQPVDGEKSKVEQYICLVCGGGGDEDRLLLCDG--CDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECGKPQVAFGFEQAPRDYTLRTFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKDFGSGFP----VKNGTFKVSPEEEG------YLTSGWNLNNMPVLEASVLTHVTADICGMKLPWLYVGMCFSSFCWHIEDHWSYSVNYLHWGEPKTWYGAPGYAAEQLEDVMKGLAPELFESQPDLLHQLVTIMNPNLLMEHGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTADWLPLGRQCVEHYRSLYRYCVFSHDEMACNIAAKA------------------------DSLELELACAVQKDMNA----MIQEEKILREKAYKLGMWHSQQVDYDILPDEERQCAKCRTTCYLSAITCPCSPEQ---------------VVCLHHTQDLC-SCPARNYTLNYKYTLAELKTFFQALTARAESYDDWASKV 730
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Match: kdm5ba (lysine (K)-specific demethylase 5Ba [Source:ZFIN;Acc:ZDB-GENE-030131-5379])

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 328/782 (41.94%), Postives = 456/782 (58.31%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIM--------------LSADHDSNIY-----ISQSTVKPKPVLHPSTTKKR---KSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPL--KRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F+ PPECPVF P+ EEF DP  +I +IRPIA  +GIC+I PP  W PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DL+ L+KLV E+GG+D +   + W +IA KMG+       S LR HYE+I+ PY +               L+ D     Y       + +V+P      +   KR   +  +S+P  E      N  +R+    A P         V+++++ +  P+  ++  +  Y+C  CG G  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +   K  + +GF  +   YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +KNG    +  E        Y    WNLN +P+ + SVL  +  +I GMK+PW YVGM FSSFCWHIEDHWS+S+NYLHWGEPKTWYG     AEQ E  M+  APELF++  DLLH + TIMNPN+LM+ GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC A+WL +GR CVEHY  L+R+CVFSHDE+ C IA  A                         S ++ L   +++ ++A    +++EE+  R K  K+ +   +Q  ++ L D+ER C  C+TTC+LSA  C C  E+               +VCL H  ++C SCP   +T  Y++TL E+      L  R + +  W + +
Sbjct:    9 FIPPPECPVFEPSWEEFADPFGFINKIRPIAENTGICKIRPPPGWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKTLDLFVLYKLVKEDGGFDVVCKERRWTQIALKMGFAPGKAIGSHLRAHYERILYPYYLFQTGANLMQNSQKPTLTNDTKDKEYKPHDLPQRQSVQPVETCTIARRAKRTEGRCFKSEP-GEVCENKPNLRRRMGSYVAKPEPGTFKMLPVQVKEEPIVQPVDGEKSKVEQYICLVCGGGGDEDRLLLCDG--CDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECGKPQVAFGFEQAPRDYTLRTFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKDFGSGFP----VKNGTFKVSPEEEG------YLTSGWNLNNMPVLEASVLTHVTADICGMKLPWLYVGMCFSSFCWHIEDHWSYSVNYLHWGEPKTWYGAPGYAAEQLEDVMKGLAPELFESQPDLLHQLVTIMNPNLLMEHGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTADWLPLGRQCVEHYRSLYRYCVFSHDEMACNIAAKA------------------------DSLELELACAVQKDMNA----MIQEEKILREKAYKLGMWHSQQVDYDILPDEERQCAKCRTTCYLSAITCPCSPEQ---------------VVCLHHTQDLC-SCPARNYTLNYKYTLAELKTFFQALTARAESYDDWASKV 731
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Match: kdm5ba (lysine (K)-specific demethylase 5Ba [Source:ZFIN;Acc:ZDB-GENE-030131-5379])

HSP 1 Score: 623.624 bits (1607), Expect = 0.000e+0
Identity = 329/779 (42.23%), Postives = 452/779 (58.02%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIM-------------LSADHDSNIY-----ISQSTVKPKPVLHPSTTKKR---KSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F+ PPECPVF P+ EEF DP  +I +IRPIA  +GIC+I PP  W PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DL+ L+KLV E+GG+D +   + W +IA KMG+       S LR HYE+I+ PY +              L+ D     Y       + +V+P      +   KR   +  +S+P  E      N  +R+    A P        +VK E  +     ++  +  Y+C  CG G  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +   K  + +GF  +   YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +KNG    +  E        Y    WNLN +P+ + SVL  +  +I GMK+PW YVGM FSSFCWHIEDHWS+S+NYLHWGEPKTWYG     AEQ E  M+  APELF++  DLLH + TIMNPN+LM+ GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC A+WL +GR CVEHY  L+R+CVFSHDE+ C IA  A                         S ++ L   +++ ++A    +++EE+  R K  K+ +   +Q  ++ L D+ER C  C+TTC+LSA  C C  E+               +VCL H  ++C SCP   +T  Y++TL E+      L  R + +  W + +
Sbjct:    9 FIPPPECPVFEPSWEEFADPFGFINKIRPIAENTGICKIRPPPGWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKTLDLFVLYKLVKEDGGFDVVCKERRWTQIALKMGFAPGKAIGSHLRAHYERILYPYYLFQTGANLMNSQKPTLTNDTKDKEYKPHDLPQRQSVQPVETCTIARRAKRTEGRCFKSEP-GEVCENKPNLRRRMGSYVAKPEPVKMLPVQVKEEPIVQPVDGEKSKVEQYICLVCGGGGDEDRLLLCDG--CDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECGKPQVAFGFEQAPRDYTLRTFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKDFGSGFP----VKNGTFKVSPEEEG------YLTSGWNLNNMPVLEASVLTHVTADICGMKLPWLYVGMCFSSFCWHIEDHWSYSVNYLHWGEPKTWYGAPGYAAEQLEDVMKSLAPELFESQPDLLHQLVTIMNPNLLMEHGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTADWLPLGRQCVEHYRSLYRYCVFSHDEMACNIAAKA------------------------DSLELELACAVQKDMNA----MIQEEKILREKAYKLGMWHSQQVDYDILPDEERQCAKCRTTCYLSAITCPCSPEQ---------------VVCLHHTQDLC-SCPARNYTLNYKYTLAELKTFFQALTARAESYDDWASKV 728
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Match: kdm5bb (lysine (K)-specific demethylase 5Bb [Source:NCBI gene;Acc:415256])

HSP 1 Score: 569.696 bits (1467), Expect = 3.888e-177
Identity = 308/757 (40.69%), Postives = 428/757 (56.54%), Query Frame = 1 
Query:  229 DWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSA------------------DHDSNIYISQSTV--KPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSD----------------------YVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV + GG+D +   + W KIA  MG+       S LR HYE+I+ PY++  S                   ++  +  + +  V  +P     P+   KR   +S  I     E       L+       +    K E+ ++  +   P++ K L+                       YVC  CG G+ ED+LL+CD   C D YH  CL PPL+ VPK  W+C  C+ +   K    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    IK G   R    P+ +  +Q     WNLN + +   SVL  +  +I GM +PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELFD+  DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPR+YH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY QLHR+CVFSHDE++C                            NM+    CLD  +   V  +++L+++EER+ R K+ KM + + E   ++ L DDER C  C+TTC+LSA  C C               +    VCL H +++C SCPIS +T  YRFTL+++  +++ +  R + +  W + +
Sbjct:    3 DWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWDLQGC-TLKIPHVERKILDLYQLNKLVADEGGFDLVCRERRWTKIAMTMGFAPGKAVGSHLRAHYERILYPYNLFQSGTNLLCLQKPGDEVNDIDKEYKPHDLLQRQNVPLQPSNTSAPARRAKRMKTESGCIKSEEGEGVENKPNLRRRMGSFVVKTEQKKEIPIQ--VKEEPVEIKELNPEPEKSKPKKKNIPPPPVSMVDLYVCLVCGKGNDEDRLLLCDG--CDDSYHTFCLIPPLTDVPKGDWRCPKCLTQECCKPQEAFGFEQAHRDYTLKAFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVGTIQEDVTVEYGADIASKEFGSGFP----IKGG---RFKIAPHDEKYLQCG---WNLNNMAMMTPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAPELFDSQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRSYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRQLHRYCVFSHDEMVC----------------------------NMAMKADCLDVVLASAVQKDMQLMIKEERELREKVRKMGVAQCELFQYDLLADDERQCVKCRTTCYLSALTCPC---------------RPGVQVCLYHTHDLC-SCPISNYTLNYRFTLDDLYPMMNAVRQRAEYYDDWASRV 699
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Match: elp1 (elongator complex protein 1 [Source:Xenbase;Acc:XB-GENE-5813351])

HSP 1 Score: 649.047 bits (1673), Expect = 0.000e+0
Identity = 340/760 (44.74%), Postives = 447/760 (58.82%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            M  +  FV PPECPVF P+ EEF DPL +I +IRPIA K+GIC+I PP DW PPF+ +V +F FTPRVQ+L ELEA +R+KL+F+ +L +F  LQGS  L+IP ++ + +D+Y L K+V   GG++ +   K W ++  +MGY+      SL + HY++I+ PY++             QS V                        SLM   N+ K  +    G            ++     G L    +  Y+C  C  GD EDKLL+CD   C D YH  CL PPLS+VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP ++  +       +          Y++  WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR  APELF+   DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WLSMGR CV HY +L RHCVFSH+EL+                              M+S   CLD  +   V  E+ +++EEE + R  I ++ + + E+  FE + DDER C  C+TTCFLSA  C C                L ++VCL H   +C SCP+      YR++LE++  LL G+++R Q + SW
Sbjct:    1 MATYIEFVPPPECPVFEPSWEEFSDPLSFIGRIRPIAEKTGICKIRPPKDWQPPFACDVKSFCFTPRVQRLNELEAMTRVKLDFLDQLGKFWELQGS-ALRIPVVDRKLLDVYALSKVVSSEGGFEVVTKEKKWSQVGNRMGYQPGKGTGSLLKLHYDRILYPYELF------------QSGV------------------------SLM-VRNKRKTSKLEAFG------------MQRRHGKGALSVSFVDLYICLFCARGDCEDKLLLCDG--CDDSYHTFCLIPPLSEVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSRDFGSGFPVMDGRRKLTADEED----------YAHCGWNLNNMPVLEQSVLAHINADISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEDVMRTLAPELFETQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLSMGRQCVSHYRRLRRHCVFSHEELI----------------------------FKMASDPECLDVGLAAAVCKEMTIMIEEETKLRELIVQLGVVQAEEEAFELVPDDERQCSSCRTTCFLSALTCSC---------------SLDQLVCLNHAEELC-SCPMQNKCLRYRYSLEDLPSLLYGVKLRAQSYESW 653
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Match: elp1 (elongator complex protein 1 [Source:Xenbase;Acc:XB-GENE-5813351])

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 340/760 (44.74%), Postives = 447/760 (58.82%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            M  +  FV PPECPVF P+ EEF DPL +I +IRPIA K+GIC+I PP DW PPF+ +V +F FTPRVQ+L ELEA +R+KL+F+ +L +F  LQGS  L+IP ++ + +D+Y L K+V   GG++ +   K W ++  +MGY+      SL + HY++I+ PY++             QS V                        SLM   N+ K  +    G            ++     G L    +  Y+C  C  GD EDKLL+CD   C D YH  CL PPLS+VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP ++  +       +          Y++  WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR  APELF+   DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WLSMGR CV HY +L RHCVFSH+EL+                              M+S   CLD  +   V  E+ +++EEE + R  I ++ + + E+  FE + DDER C  C+TTCFLSA  C C                L ++VCL H   +C SCP+      YR++LE++  LL G+++R Q + SW
Sbjct:    1 MATYIEFVPPPECPVFEPSWEEFSDPLSFIGRIRPIAEKTGICKIRPPKDWQPPFACDVKSFCFTPRVQRLNELEAMTRVKLDFLDQLGKFWELQGS-ALRIPVVDRKLLDVYALSKVVSSEGGFEVVTKEKKWSQVGNRMGYQPGKGTGSLLKLHYDRILYPYELF------------QSGV------------------------SLM-VRNKRKTSKLEAFG------------MQRRHGKGALSVSFVDLYICLFCARGDCEDKLLLCDG--CDDSYHTFCLIPPLSEVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSRDFGSGFPVMDGRRKLTADEED----------YAHCGWNLNNMPVLEQSVLAHINADISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEDVMRTLAPELFETQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLSMGRQCVSHYRRLRRHCVFSHEELI----------------------------FKMASDPECLDVGLAAAVCKEMTIMIEEETKLRELIVQLGVVQAEEEAFELVPDDERQCSSCRTTCFLSALTCSC---------------SLDQLVCLNHAEELC-SCPMQNKCLRYRYSLEDLPSLLYGVKLRAQSYESW 653
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Match: elp1 (elongator complex protein 1 [Source:Xenbase;Acc:XB-GENE-5813351])

HSP 1 Score: 640.958 bits (1652), Expect = 0.000e+0
Identity = 340/760 (44.74%), Postives = 447/760 (58.82%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            M  +  FV PPECPVF P+ EEF DPL +I +IRPIA K+GIC+I PP DW PPF+ +V +F FTPRVQ+L ELEA +R+KL+F+ +L +F  LQGS  L+IP ++ + +D+Y L K+V   GG++ +   K W ++  +MGY+      SL + HY++I+ PY++             QS V                        SLM   N+ K  +    G            ++     G L    +  Y+C  C  GD EDKLL+CD   C D YH  CL PPLS+VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP ++  +       +          Y++  WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR  APELF+   DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WLSMGR CV HY +L RHCVFSH+EL+                              M+S   CLD  +   V  E+ +++EEE + R  I ++ + + E+  FE + DDER C  C+TTCFLSA  C C                L ++VCL H   +C SCP+      YR++LE++  LL G+++R Q + SW
Sbjct:    1 MATYIEFVPPPECPVFEPSWEEFSDPLSFIGRIRPIAEKTGICKIRPPKDWQPPFACDVKSFCFTPRVQRLNELEAMTRVKLDFLDQLGKFWELQGS-ALRIPVVDRKLLDVYALSKVVSSEGGFEVVTKEKKWSQVGNRMGYQPGKGTGSLLKLHYDRILYPYELF------------QSGV------------------------SLM-VRNKRKTSKLEAFG------------MQRRHGKGALSVSFVDLYICLFCARGDCEDKLLLCDG--CDDSYHTFCLIPPLSEVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSRDFGSGFPVMDGRRKLTADEED----------YAHCGWNLNNMPVLEQSVLAHINADISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEDVMRTLAPELFETQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLSMGRQCVSHYRRLRRHCVFSHEELI----------------------------FKMASDPECLDVGLAAAVCKEMTIMIEEETKLRELIVQLGVVQAEEEAFELVPDDERQCSSCRTTCFLSALTCSC---------------SLDQLVCLNHAEELC-SCPMQNKCLRYRYSLEDLPSLLYGVKLRAQSYESW 653
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Match: lamp2 (lysosomal-associated membrane protein 2 [Source:Xenbase;Acc:XB-GENE-962456])

HSP 1 Score: 640.958 bits (1652), Expect = 0.000e+0
Identity = 333/786 (42.37%), Postives = 475/786 (60.43%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADHDSNIYIS---------------QSTVKPKPVLHPSTTKKRK-----SLQSDPIDESLMETSNELKRLQFSGAG---PRIYASTKDEVKLEDDLVSGPLKR--KCLSD---YVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            FV PPECPVF PT EEF DP  +I +IRPIA +SGIC++ PP DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DL++L+KLV E+GG+D +   + W KIATKMG+       S +R HYE+I+ PY++  S  +    +++               + +V+P     P+   KR      +++++P++   +      +R+ ++         +   K E+   + ++  P  R  KC S    Y C  CGSG  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +  SK    +GF  +S  YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +++GK  R   E  +     Y N  WNLN +PI + SVL  +  +I GMK+PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELF    DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +WL +GR C+EHY  L+R+CVFSHDE++C +A                        +     D+ L +++++ + +    +++EER  R  + +M + K E+   E L DD+R C  C+TTCF+SA  C C    L               VCL H+ ++C+ CP+ ++T  YR+T++++  +++ +++R + + SW  ++
Sbjct:   16 FVPPPECPVFEPTWEEFADPFAFINKIRPIAERSGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLFQLNKLVAEDGGFDLVCRERKWTKIATKMGFSLGKAVGSHIRGHYERILHPYNLFQSGTNLLKPFLAPDLKDKEYKPHDIPQRQSVQPPENCTPARRAKRMKSEVVTIKTEPVEVPELRPRALRRRMGYTPTKCEKEDSFLIVKKEIV--EPVIEKPKARNKKCRSQVDLYACLVCGSGSDEDRLLLCDG--CDDSYHTFCLIPPLQDVPKGDWRCPKCLAQECSKPQEAFGFEQASRDYTLRMFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFP----VRDGK-FRVKPEDEV-----YLNCGWNLNNMPIMQPSVLAHVTADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEQLEEVMKKLAPELFIAQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCIEHYRGLNRYCVFSHDEMICKMA------------------------IKADKLDVVLASSVQKDMAS----MIDEERALREAVRQMGVLKSEKMDLELLADDDRQCTKCKTTCFISAVFCSCSPGAL---------------VCLHHVEDLCD-CPVYKYTLGYRYTVDDLYPMMNAVKLRAESYDSWATEV 741
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Match: lamp2 (lysosomal-associated membrane protein 2 [Source:Xenbase;Acc:XB-GENE-962456])

HSP 1 Score: 640.573 bits (1651), Expect = 0.000e+0
Identity = 333/768 (43.36%), Postives = 464/768 (60.42%), Query Frame = 1 
Query:   88 EHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPV----LHPSTTKKRKSLQSDPI--DESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            +   FV PPECPVF PT EEF DP  +I +IRPIA +SGIC++ PP DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DL++L+KLV E+GG+D +   + W KIATKMG+       S +R HYE+I+ PY++  S    +N+ +   T+K +PV    L P   ++R          ++S +    E+          R       +  L+ DL            Y C  CGSG  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +  SK    +GF  +S  YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +++GK  R   E  +     Y N  WNLN +PI + SVL  +  +I GMK+PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELF    DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +WL +GR C+EHY  L+R+CVFSHDE++C +A                        +     D+ L +++++ + +    +++EER  R  + +M + K E+   E L DD+R C  C+TTCF+SA  C C    L               VCL H+ ++C+ CP+ ++T  YR+T++++  +++ +++R + + SW  ++
Sbjct:   38 DEMEFVPPPECPVFEPTWEEFADPFAFINKIRPIAERSGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLFQLNKLVAEDGGFDLVCRERKWTKIATKMGFSLGKAVGSHIRGHYERILHPYNLFQSG---TNLLV--VTIKTEPVEVPELRPRALRRRMGYTPTKCEKEDSFLIVKKEIVEPVIEKPKAR-----NKKFALQVDL------------YACLVCGSGSDEDRLLLCDG--CDDSYHTFCLIPPLQDVPKGDWRCPKCLAQECSKPQEAFGFEQASRDYTLRMFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFP----VRDGK-FRVKPEDEV-----YLNCGWNLNNMPIMQPSVLAHVTADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEQLEEVMKKLAPELFIAQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCIEHYRGLNRYCVFSHDEMICKMA------------------------IKADKLDVVLASSVQKDMAS----MIDEERALREAVRQMGVLKSEKMDLELLADDDRQCTKCKTTCFISAVFCSCSPGAL---------------VCLHHVEDLCD-CPVYKYTLGYRYTVDDLYPMMNAVKLRAESYDSWATEV 725
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Match: Kdm5c (lysine (K)-specific demethylase 5C [Source:MGI Symbol;Acc:MGI:99781])

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 374/888 (42.12%), Postives = 510/888 (57.43%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQN 2535
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E       LL+R +N
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE-------LLQRLKN 817
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Match: Kdm5c (lysine (K)-specific demethylase 5C [Source:MGI Symbol;Acc:MGI:99781])

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 374/888 (42.12%), Postives = 510/888 (57.43%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQN 2535
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E       LL+R +N
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE-------LLQRLKN 817
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Match: Kdm5a (lysine (K)-specific demethylase 5A [Source:MGI Symbol;Acc:MGI:2136980])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 377/909 (41.47%), Postives = 515/909 (56.66%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSA-------------DHDSNIYISQSTVKPKPV------LHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLV-------------------SGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNM-DLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQ---NSDDCSKLDES---DEVRLHVPKSVLIDCVRENGSVEIKNI 2688
            FV PPECPVF P+ EEF DPL +I +IRP A K+GIC+I PP DW PPF+  V TF+FTPRVQ+L ELEA +R++L+F+ +L++F  LQGS  LKIP +  + +DLY L K+V   GG++ +   K W K+ +++GY       SL ++HYE+I+ PY++  S                     +  + ++P P       + P  T++ KS QSD  +   +  + ELK+LQ  GAGP++          ED++                     G L    +  YVC  CG G+ EDKLL+CD   C D YH  CL PPL  VPK  W+C  CV E  +K    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP           + +G+  M     +Y+   WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR+ APELF++  DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL +GR CV HY +L RHCVFSH+EL+                              M++   CLD  +   V  EL L+ EEE + R  + +M +   E+ +FE + DDER C  C+TTCFLSA  C C  E               R+VCL H  ++C SCP+      YR+ LE++  LL G++VR Q + +W   +    +   ASF     + +  L +L++ L +  +  +   + F K R  ++  +   +V +  L   Q    S D  K       +E++  V + V + CV    + ++KN+
Sbjct:   13 FVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGS-TLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKS-QSDSGE---VNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDG--CDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFP-----------KKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELI----------------------------FKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPE---------------RLVCLYHPTDLC-SCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALS---ASF-----NHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRQSSDSGKTRTKLTVEELKAFVQQLVSLPCVISQ-TRQVKNL 849
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Match: Kdm5d (lysine (K)-specific demethylase 5D [Source:MGI Symbol;Acc:MGI:99780])

HSP 1 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 359/829 (43.31%), Postives = 489/829 (58.99%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADH----DSNIYISQ---STVKPKPV-----LHPST----TKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA----------STKDEVKLEDDLVSGPL------------------------------------------KRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKA 2376
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  + +DLY L+K+V E GGY+ I  ++ W ++A ++ Y S     SL R+HYE+II PY+I  S  +    +++ + S+      KP  +     + PS     +++ K LQ +P   E  +E + ELK+LQ  GAGP++              KD  + + + V+ P                                             + ++ YVC+ C  GD+ DK L+CD   C D YH  CL PPLS+VPK  W+C  C+L      P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP    + N K   +  E       +Y+   WNLN++P+  +SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M++  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL +GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  +     YR+TL+E+  +L  L++R + F +W   ++A
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERKILDLYSLNKIVMEEGGYEAICKDRRWARVAQRLNYPSGKNIGSLLRSHYERIIYPYEIFQSGANLVQCNTDPFDSEERDKEYKPHSIPLRQSVQPSKFSCYSRRGKRLQPEPEPTEEDIEKNPELKKLQIYGAGPKMIGLGLKAKEKTLRKKDSKQPDKEEVTCPATIVVKGEASEFGKVTSAFSDKNLNHSFEPCMKMTMQLRNNHSSTQFMNSYVCRICSRGDEVDKFLLCDG--CSDNYHIFCLLPPLSEVPKGVWRCPKCILAECKSPPEAFGFEQATQEYTLQSFGEMADSFKADYFNMPVH-MVPTEVVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFP----VNNSKWDLSPEEK------EYAACGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEDVMKRLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPVGRQCIEHYRRLRRYCVFSHEELICKMA-------------AFPEK---------------LDLNLAVAVHKEMFIMVQEERRLRKTLLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDSL---------------VCLSHINDLCK-CSRNRQYLRYRYTLDELPAMLQKLKIRAESFDNWANKVQA 778
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Match: Kdm5a (lysine (K)-specific demethylase 5A [Source:MGI Symbol;Acc:MGI:2136980])

HSP 1 Score: 661.374 bits (1705), Expect = 0.000e+0
Identity = 368/870 (42.30%), Postives = 497/870 (57.13%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSA-------------DHDSNIYISQSTVKPKPV------LHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLV-------------------SGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNM-DLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDC 2589
            FV PPECPVF P+ EEF DPL +I +IRP A K+GIC+I PP DW PPF+  V TF+FTPRVQ+L ELEA +R++L+F+ +L++F  LQGS  LKIP +  + +DLY L K+V   GG++ +   K W K+ +++GY       SL ++HYE+I+ PY++  S                     +  + ++P P       + P  T++ KS QSD  +   +  + ELK+LQ  GAGP++          ED++                     G L    +  YVC  CG G+ EDKLL+CD   C D YH  CL PPL  VPK  W+C  CV E  +K    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP           + +G+  M     +Y+   WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR+ APELF++  DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL +GR CV HY +L RHCVFSH+EL+                              M++   CLD  +   V  EL L+ EEE + R  + +M +   E+ +FE + DDER C  C+TTCFLSA  C C  E               R+VCL H  ++C SCP+      YR+ LE++  LL G++VR Q + +W   +    +   ASF     + +  L +L++ L +  +  +   + F K R  ++  +   +V +  L   Q    C
Sbjct:   13 FVPPPECPVFEPSWEEFTDPLSFIGRIRPFAEKTGICKIRPPKDWQPPFACEVKTFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGS-TLKIPVVERKILDLYALSKIVASKGGFEIVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPDLDLKEKVEAEVLSTDIQPSPERGTRMNIPPKRTRRVKS-QSDSGE---VNRNTELKKLQIFGAGPKVVGLAVGAKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDG--CDDSYHTFCLLPPLPDVPKGDWRCPKCVAEECNKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFP-----------KKDGQRKMLPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELI----------------------------FKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVVMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPE---------------RLVCLYHPTDLC-SCPMQNKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVNRVTEALS---ASF-----NHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCGSVAQLLLSKKQKHRIC 811
[Close]
BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Match: sp|Q30DN6|KDM5D_CANLF (Lysine-specific demethylase 5D OS=Canis lupus familiaris OX=9615 GN=KDM5D PE=2 SV=1)

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 362/822 (44.04%), Postives = 484/822 (58.88%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADH--DSNIYISQSTVKPK--------------PVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIY-----------------------ASTKDEVKLEDDLVSGPLKRKCLSD-----------------------YVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIK 2373
            F+ PPECPVF PT  EF+DPL+YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y +     S LR+HYE+II PY++  S  +    N Y   +  K K              P    S +++ K LQ DP   E  +E + ELK+LQ  GAGP++                        A    E   ED+ V   L R+ LS                        YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++P+  W+C  C++    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP          ++    P  +   +Y+   WNLN++P+  +SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  M++  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L++R + F +W   ++
Sbjct:    8 FLPPPECPVFEPTWAEFRDPLDYITKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVMEEGGYEAICKDRRWARVAQRLNYPAGKNIGSLLRSHYERIIYPYEMFQSGANLVQCNTYPFDNEEKDKEYKPHGIPLRQSVQPSTFSSYSRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGVLCPRAVLMKEEPREDERVMSSLPREDLSHSVEPCTKMTMQLRTHSSAQFIDLYVCRICSRGDEDDKLLLCDG--CDDTYHIFCLIPPLPEIPRGVWRCPKCIMAECKRPPEAFGFEQATQEYTLQSFGEMADSFKADYFSMPVH-MVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPV-------SSSQRILSPEEE---EYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEQLEEVMKRLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMA-------------AFPEK---------------LDLNLAVAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKIRAESFDTWANKVR 771
[Close]
BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Match: sp|Q38JA7|KDM5C_CANLF (Lysine-specific demethylase 5C OS=Canis lupus familiaris OX=9615 GN=KDM5C PE=2 SV=1)

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 373/888 (42.00%), Postives = 509/888 (57.32%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA----------------------------STKDEVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQN 2535
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++                               +  +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +N       + +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E       LL+R +N
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEESGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDN-------KRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE-------LLQRLKN 817
[Close]
BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Match: sp|P41230|KDM5C_MOUSE (Lysine-specific demethylase 5C OS=Mus musculus OX=10090 GN=Kdm5c PE=1 SV=4)

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 374/888 (42.12%), Postives = 510/888 (57.43%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQN 2535
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E       LL+R +N
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE-------LLQRLKN 817
[Close]
BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Match: sp|P29375|KDM5A_HUMAN (Lysine-specific demethylase 5A OS=Homo sapiens OX=9606 GN=KDM5A PE=1 SV=3)

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 370/865 (42.77%), Postives = 503/865 (58.15%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIM---------------LSADHDSNIYISQSTVKPKPV----LHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLV-------------------SGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQN 2577
            FV PPECPVF P+ EEF DPL +I +IRP+A K+GIC+I PP DW PPF+  V +F+FTPRVQ+L ELEA +R++L+F+ +L++F  LQGS  LKIP +  + +DLY L K+V   GG++ +   K W K+ +++GY       SL ++HYE+I+ PY++                L    +  +  + +   P+P     + P  T++ K+ QS+  D S    + ELK+LQ  GAGP++          ED++                     G L    +  YVC  CG G+ EDKLL+CD   C D YH  CL PPL  VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP    +K+G   R    P  +   +Y+   WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV S  AEQ E  MR+ APELF++  DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL +GR CV HY +L RHCVFSH+EL+                              M++   CLD  +   V  EL L+ EEE + R  + +M +   E+ +FE + DDER C  C+TTCFLSA  C C  E               R+VCL H  ++C  CP+ +    YR+ LE++  LL G++VR Q + +W + +    TE   + +AN   K+  L +L++ L +  +  +   + F K R  ++  +   +V +  L   Q 
Sbjct:   13 FVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGS-TLKIPVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKT-QSESGDVS---RNTELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDG--CDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFP----VKDG---RRKILPEEE---EYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELI----------------------------FKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPE---------------RLVCLYHPTDLC-PCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRV----TE---ALSANFNHKK-DLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQK 807
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BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Match: sp|P41229|KDM5C_HUMAN (Lysine-specific demethylase 5C OS=Homo sapiens OX=9606 GN=KDM5C PE=1 SV=2)

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 370/874 (42.33%), Postives = 504/874 (57.67%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKP---------------------KPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKD-------------------------EVKLE-----------DDLVSGP---------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCE 2493
            F+ PPECPVF P+  EF+DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEAQ+R+KLN++ ++++F  +QGS  LKIPN+  R +DLY L K+V E GGY+ I  ++ W ++A ++ Y       SL R+HYE+I+ PY++     + S   + Q   +P                     +P    S  ++ K LQ DP   E  +E + ELK+LQ  GAGP++       KD                         +VK+E           ++L   P         L+R     + +  YVC+ C  GD++DKLL+CD   C D YH  CL PPL ++PK  W+C  CV+    + P  +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP  +       ++ +  P  +   +Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE  E  M+K  PELFD+  DLLH + T+MNPN LM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL+C +A               P K               LD N+   VH E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    + L               VCL HIN++C  C  S     YR+TL+E+  +L  L+VR + F +W   ++        +    +  KR SL++L+   +E  E  F + E
Sbjct:    8 FLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSS-LKIPNVERRILDLYSLSKIVVEEGGYEAICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEM-----YQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDG--CDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSD-------SKRHLTPEEE---EYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAAC-------------PEK---------------LDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGL---------------VCLSHINDLCK-CSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVR-------VALEVEDGRKR-SLEELRALESEARERRFPNSE 810
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BLAST of Lysine-specific demethylase vs. TrEMBL
Match: A0A481NV48 (Lysine-specific demethylase OS=Dugesia japonica OX=6161 GN=lsd PE=2 SV=1)

HSP 1 Score: 2628.97 bits (6813), Expect = 0.000e+0
Identity = 1257/1443 (87.11%), Postives = 1348/1443 (93.42%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESDEVRLHVPKSVLIDCVRENGSVEIKNINVASLTEENLAHMNQTLIRFPLKLPCDQFEQMVARLLQWRQDSHTLMALNMNNPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGVFSLPVNLVKESTVFELVNHGETLISSVKETANELGDLGARFLLPISVSLQPALDGLYDVVAEINRLRDELSQLPKRGGISSQILASLKEATERCLCMGVRVSELDETRTRLYKACVDVILVTKPGRFVDMQHASQLVQLGSALFSEAVLDRESSPLTQKHLSSKTQITLMNRSIKKLKLSYVGCNTEHANNEICQLGCSDFDFLKILLPRFFSLDQNLNRDRLAHNNVQFLQIWHSCPVNENQIISLMRLYQTMIVEELSSIESMHSNKSSIAHSDLYCCVCEQSPIEKNSSYCMLCKPRSNRPTINEMAQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYSEIKNAKLTVPVCIKELFSQNTSTERKSIELSRIKDLFINLTYLRRVGYCLEVNVESYVAVXXXXXXXXXXXXXXXXAYHHDANIEADSSVTSVNI 4410
            MEEHFTFVSPPECPVFRPTKEEF+DPLEYIEQIRPIA+KSGICRIIPPDDWTPPFSVNVN+FQFTPRVQKLYELEAQSRIKLNFMTKLSQFV+LQGSDKLK+PNINGRHVDLYKLHKLVHE+GGYDHIIANKLW KIA KMGYK+ S AYSLRTHYEKIILPYD+M++ DHDSNIYI+   VKPKPVLHPSTTKKRKS+Q +PID SLMETSNELKRLQFSGAGPRI+ +TKDE+K+E+DL+SGPLKRKCLSDYVCKTCGSGDKED+LLICDN+ECQDCYHCDCL PPL+QVPKQSWKCHNCVLEVLSKKP+EYGFPSSSITYTLYEFGKSAD+FKANYFGKELHELVPC++VEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPT ENIKNGKC RNNGEPNMDLA+QYS ELWNLN+LPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWS+SINYLHWGEPKTWYGVSSENA QFE AMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWL MGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNI ++EIP+KYPLMSGLNM S+DI LDTNIRRTVHAELE+++EEER+ R+KIE +N+ K EQT+FENLKDDERAC ICQTTCFLSAFRC C+N+ELKM +D+K E K +RIVCLRHI+NVC+ CPIS+WTFLYRFTL +MDRLLSGLEVRLQDFHSWEADIKAHCTEGP SF   EPDKRWSLDQLQMRLNEG ECGFDSCEEFVK+RGLLERGQNLTNVCKHWLKAIQNS+DCSKLDE DE R HVPKSVLIDCVR+NGSVEIKNINVASLTEENLAHMNQTL RFPL+LPC+QFEQMVARLLQWRQDSHTLM LNM NPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEG FSLP+NLVKESTVFELV HGETLISSVKETA+ELGDLG RFL PISVSLQPALDGLY+VVAEINRLR+ELSQLPKR GISSQILASLKEATERCLCMGVRV+ELD+TRTRLYKAC+DVILVTKPGRF+DM HASQL+QLGSALFSE VLDRESS LTQKHLS KTQITLM+RSI+KLK SY+GCN EH NNE C  GC+DFDFLKILLPR+FS DQNLNR+RLA N+ QFLQIWHS  VNENQIISLMRLYQTMIVEELSSIE+M+S K    HSD +CCVCEQS  E NSSYC LCKPRSNRP+INE+AQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFY+EIKN+KLTVPVCIKELFSQ +S E+K I+  R KDLFINLTYLRRVGYCLEVNVESYVAV  + I   S   + +S+ +H  N+E  S++TS++I
Sbjct:    1 MEEHFTFVSPPECPVFRPTKEEFRDPLEYIEQIRPIAIKSGICRIIPPDDWTPPFSVNVNSFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVKLQGSDKLKVPNINGRHVDLYKLHKLVHESGGYDHIIANKLWPKIANKMGYKNNSHAYSLRTHYEKIILPYDMMIAGDHDSNIYIAPPMVKPKPVLHPSTTKKRKSVQPEPIDNSLMETSNELKRLQFSGAGPRIFINTKDELKIEEDLISGPLKRKCLSDYVCKTCGSGDKEDRLLICDNDECQDCYHCDCLIPPLAQVPKQSWKCHNCVLEVLSKKPVEYGFPSSSITYTLYEFGKSADRFKANYFGKELHELVPCNTVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTFENIKNGKCVRNNGEPNMDLAVQYSTELWNLNVLPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSYSINYLHWGEPKTWYGVSSENAIQFETAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLLMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNISEDEIPIKYPLMSGLNMCSSDIYLDTNIRRTVHAELEIILEEERKNRLKIEALNILKTEQTMFENLKDDERACGICQTTCFLSAFRCNCVNDELKMDDDLKIENKSRRIVCLRHIDNVCSVCPISDWTFLYRFTLADMDRLLSGLEVRLQDFHSWEADIKAHCTEGPISFDVTEPDKRWSLDQLQMRLNEGGECGFDSCEEFVKARGLLERGQNLTNVCKHWLKAIQNSEDCSKLDEFDESRHHVPKSVLIDCVRDNGSVEIKNINVASLTEENLAHMNQTLTRFPLRLPCEQFEQMVARLLQWRQDSHTLMGLNMINPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGAFSLPINLVKESTVFELVTHGETLISSVKETASELGDLGTRFLFPISVSLQPALDGLYEVVAEINRLREELSQLPKR-GISSQILASLKEATERCLCMGVRVNELDDTRTRLYKACLDVILVTKPGRFIDMHHASQLIQLGSALFSEGVLDRESSTLTQKHLSGKTQITLMSRSIRKLKASYIGCNIEHINNESCSSGCNDFDFLKILLPRYFSFDQNLNRERLAQNSGQFLQIWHSSAVNENQIISLMRLYQTMIVEELSSIEAMNSKKPFEVHSDSHCCVCEQSQCELNSSYCSLCKPRSNRPSINEVAQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYAEIKNSKLTVPVCIKELFSQTSSYEKKPIDNDRFKDLFINLTYLRRVGYCLEVNVESYVAV--LSILIESIKNDINSSNYHSVNVEPKSNITSIDI 1440
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BLAST of Lysine-specific demethylase vs. TrEMBL
Match: A0A4Z2D5L6 (Lysine-specific demethylase 5D OS=Schistosoma japonicum OX=6182 GN=EWB00_004283 PE=4 SV=1)

HSP 1 Score: 790.03 bits (2039), Expect = 0.000e+0
Identity = 441/1026 (42.98%), Postives = 606/1026 (59.06%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHP---STTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLE-YGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKN--GKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRR-----------------TVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMK------------TEKKLK---------------------RIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWE---------ADIKAHCTEG-------PASF--TANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDES--------DEVRLHVPKSV-----------------LIDCVRENGSVEIKN-INVASLTEENLAHMNQTL-IRFPLKLPCDQFEQMVARLLQ----WRQDSHTLMALNMN 2844
            M  +F+FV PPE PVF P+ EEF+DPL Y+ +IRPI VK+GIC+I+PP  W PPF+VN+  F FTPR+Q+LYELEA SRIKLNF+++L +FV+LQG DK+++P+I+GR++DLY LHK V E GGY  +   + W  IA K+GY++   A++++T+YEK++LP+D  +S       Y SQ T   K +  P   S  + RK    D ID S    SNEL+ LQF GAG +           +D L S       + +Y C+ CG GD E  LL+CD + CQ CYH  CL PPL  +PK  WKC  C+ +V+   P+E YGFP SS TY+L+EFG  AD+FK+ YF +   + VPC  VE+EFWRILQ +NDD++VEYGADIHSS QGSGFPT   +KN  G  ++      +  A +Y++  WNLNILP+  +SVLRFI+GNIDGMK+PWCYVGMVFSSFCWHIEDHWS+SIN+ HWGEPKTWYGVS  +A+ FE A++K A ELFD   DLLHHITT +NPNIL  EGVP+YRTDQ  G+FVVTFPRAYHAGFNQGFNFAEAVN C  +WL +GR C+EHYA++ RHCVFS+DELLCT+AE A+   + +P+E + +  P+ + ++ S     L+++IR                   VH E   V++EER+ R  + +  +TK  +  F+ + DD R C  C TT FLS   C CI E     E +K            T +K K                      +VCL+H++ +C  CP S +   Y +++EE+  L   L  RL  F+SW+         +D    C++         +SF  + N      +L +L+MRL EG   G+ + + +  ++ +L+RG++L  +C     +I  + +  K            D VR    +                   +I     NG V + + ++V +  E +L  + ++   + PL L  D   Q+V +LL     WRQ S  ++ L  N
Sbjct:    1 MPSNFSFVPPPEAPVFYPSPEEFEDPLAYLMKIRPICVKTGICKIVPPKCWNPPFAVNMKEFSFTPRIQRLYELEAHSRIKLNFISRLYKFVQLQGGDKIRVPSISGRYLDLYNLHKHVTEAGGYRQVCDRQSWSGIAEKLGYQN-RHAHTIKTNYEKLLLPFDQAVS-------YPSQPT---KAIHQPRLCSYKRCRKPTDEDRIDYS---ASNELRNLQFFGAGRKAAVP-------KDGLPSNFKPELNIDEYNCRVCGYGDDETNLLVCDTDSCQACYHLYCLDPPLRSIPKCQWKCPECI-KVICCNPIEVYGFPQSSKTYSLHEFGVMADQFKSTYFKRPCTD-VPCGEVEREFWRILQEYNDDVVVEYGADIHSSSQGSGFPTKSMLKNLVGTASQ------LAEAKKYADSPWNLNILPLLDRSVLRFIKGNIDGMKIPWCYVGMVFSSFCWHIEDHWSYSINFNHWGEPKTWYGVSRLHADDFERAIKKHASELFDQAPDLLHHITTNVNPNILQAEGVPIYRTDQHCGEFVVTFPRAYHAGFNQGFNFAEAVNICLPDWLPIGRACIEHYAEIKRHCVFSNDELLCTLAEVAV--GNVLPEEILTITNPVNNCISGSECSDNLESDIREKLPPGCSTSGLDIGAVAIVHQEFACVLKEERKLREIVTQSGITKSRKVRFDEMPDDARVCDFCLTTLFLSGVSCSCIYESNTDIESLKNQTNHSLDHHSTTARKYKMFNDSSSTMDESNEEGKRSPSHMVCLKHVSELCTKCPRSVYVLNYHYSIEELCNLEQSLGNRLSHFYSWKNQLSFLIKPSDSNTLCSQSIKQEPNNSSSFIDSNNSTSATMTLVELEMRLAEGKTSGYHTDDIYNDAKAILDRGKHLQQICARLKPSIIGTGNIDKFKNPLTSISSTVDPVRFQTRRPATFSVATSSTGGCATPQKIIKLPSNNGFVVLNHELDVNNPREYDLLRLMESCEQQHPLNLFEDSSVQLVKQLLNQLTTWRQSSRDIINLLCN 995
[Close]
BLAST of Lysine-specific demethylase vs. TrEMBL
Match: A0A504Y4G6 (Lysine-specific demethylase 5D OS=Fasciola gigantica OX=46835 GN=FGIG_03610 PE=4 SV=1)

HSP 1 Score: 786.563 bits (2030), Expect = 0.000e+0
Identity = 429/1006 (42.64%), Postives = 586/1006 (58.25%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYP-----------------LMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLK----------------------RIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWE------------ADIKAH-----CTEGPASFTANEP--------------DKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESD----EVRLHVPKSV-----------LIDCVRENGSVEI----KNINVASLTEENLAHMNQTLIRF-PLKL---PCDQ-FEQMVARLLQWRQDS 2817
            M++ FTFV PPE PVFRPT+EEF+DPLEY+ +IR I  K+GIC+IIPP  W PPF+VN+  F FTPRVQ+LYELEA SRIKLNF+++L +F R QG DK+++P+I GR +DLY LHK V  +GGY+ I  +  W  +A K+GY+S   A S++T+YEK++L +D         N+  S+ +   +     + +K+ + L    +++    T  EL+ LQF G GP+      D  +      +     + + DY C+ C  GD ED LL+CD + CQ CYH  CL PPL  VPK  WKC  C+  V  + P  YGFP SS +Y+L+EFG  AD+FK+ YFGK   E V C++VE EFWRILQ +NDD++VEYGADIHSS +GSGFPT   + N           ++ A  Y+   WNLNILP+  +SVLRFI+GNIDGMK+PWCYVGMVFSSFCWHIEDHWS+SIN+ HWGEPKTWYGVS  +AE FE AMRK APELFD   DLLHHITT MNPNIL  EGVP+YRTDQ  G+FVVTFPRAYHAGFNQGFNFAEAVN C  +WL +GR CVEHY+++ RHCVFS+DELLCT+AE A+      P++ + V  P                 L S L    +   LD +    VH E  +++  ER+ R  ++   + ++E+  F+ L DD R C +C TT FLS  RC C  E     +   T  K +                       +VCL+H++ +C+SC I+ +T  Y +TLEE++ L + L  RL+ F++W              D+K+       T  P+     E               D   +L+ L   L EG E G+ + + F ++  L++RG  L   C   +  I  + +   LD++       +L +P +            +++ V+   SV        +++ +  E +L  + ++  +  P+ L   PC Q  +  + RL +WRQ S
Sbjct:    1 MDDGFTFVPPPEAPVFRPTEEEFRDPLEYLMKIRHIGTKTGICKIIPPKSWNPPFAVNMKEFSFTPRVQRLYELEAHSRIKLNFISRLYKFFRTQGGDKIRVPSIGGRFLDLYTLHKEVRSSGGYEKICIDHSWASVAEKLGYQS-RHASSIKTNYEKLLLAFD---------NLLYSELSADKRSSERKTGSKRLRLLPCSDLEDIGTSTRRELRNLQFFGPGPKAAVPLLDTGRA----TASDRPDRHIDDYFCRVCDRGDDEDNLLVCDTDACQACYHTYCLKPPLRSVPKCQWKCPECIRSVCLQPPEPYGFPQSSKSYSLHEFGVMADEFKSKYFGKPCTE-VSCAAVEHEFWRILQEYNDDVVVEYGADIHSSSKGSGFPTEARLPN----LVGTAQQLEDAKMYAISPWNLNILPLLDRSVLRFIKGNIDGMKIPWCYVGMVFSSFCWHIEDHWSYSINFNHWGEPKTWYGVSRFHAEDFERAMRKHAPELFDQSPDLLHHITTNMNPNILQGEGVPIYRTDQHCGEFVVTFPRAYHAGFNQGFNFAEAVNICLPDWLPIGRECVEHYSEIKRHCVFSNDELLCTLAEVAIGRCR--PEDILLVTNPYTPSKQRTSVARRGAQDLKSRLPPGCSTAGLDISAIAAVHQEFTILLTNERRLRDSVQAAGVKQMEKVRFDELPDDIRVCDVCLTTLFLSGVRCSCAAESPTQTKAQSTGVKRRTTDTAENSDHDSSFNDEDRPKSHMVCLKHVDQLCSSCAIASFTLKYHYTLEELEELETALAYRLKHFYAWRDRLASLLKSAETVDVKSKIERDPVTSSPSIIVKKESSDNMSDQASISEIWDTTITLNDLLEMLREGREAGYHTDDIFSEAESLVKRGNQLLVTCSSVIPWISAASETFDLDKTTNQLVRFQLRLPATFNVVTGSPTTASVVEGVKSTPSVSFVTLQHEMDLHNPRELDLTRLLESCKQLHPINLLQEPCVQSVKHFLDRLAEWRQVS 985
[Close]
BLAST of Lysine-specific demethylase vs. TrEMBL
Match: A0A4E0RUD1 (Lysine-specific demethylase 5D OS=Fasciola hepatica OX=6192 GN=D915_003947 PE=4 SV=1)

HSP 1 Score: 783.482 bits (2022), Expect = 0.000e+0
Identity = 433/1010 (42.87%), Postives = 589/1010 (58.32%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIML----SADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYP-----------------LMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLK----------------------RIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWE------------ADIKAHCTEGPASFTANEPDKR---------------W----SLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESD----EVRLHVPKSV-----------LIDCVRENGSVEI----KNINVASLTEENLAHMNQTLIRF-PLKL---PCDQ-FEQMVARLLQWRQDS 2817
            M++ FTFV PPE PVFRPT+EEF+DPLEY+ +IR I  K+GIC+IIPP  W PPF+VN+  F FTPRVQ+LYELEA SRIKLNF+++L +F R QG DK+++P+I GR +DLY LHK V  +GGY+ I  +  W  +A K+GY+S   A S++T+YEK++L +D +L    SAD  SN   + S             K+ + L    +++    T  EL+ LQF G GP+      D  +      +     + + DY C+ C  GD ED LL+CD + CQ CYH  CL PPL  VPK  WKC  C+  V  + P  YGFP SS +Y+L+EFG  AD+FK+ YFGK   E V C++VE EFWRILQ +NDD++VEYGADIHSS +GSGFPT   + N           ++ A  Y+   WNLNILP+  +SVLRFI+GNIDGMK+PWCYVGMVFSSFCWHIEDHWS+SIN+ HWGEPKTWYGVS  +AE FE AMRK APELFD   DLLHHITT MNPNIL  EGVP+YRTDQ  G+FVVTFPRAYHAGFNQGFNFAEAVN C  +WL +GR CVEHY+++ RHCVFS+DELLCT+AE A+      P++ + V  P                 L S L    +   LD +    VH E  +++  ER+ R  ++   + ++E+  F+ L DD R C +C TT FLS  RC C  E     +   T  K +                       +VCL+H++ +C+SC I+ +T  Y +TLEE++ L + L  RL+ F++W              D+K+     P + +++   K+               W    +L+ L   L EG E G+ + + F ++  L++RG  L   C   +  I    +   LD++       +L +P +            +++ V+   SV        +++ +  E +L  + ++  +  P+ L   PC Q  +  + RL +WRQ S
Sbjct:    1 MDDGFTFVPPPEAPVFRPTEEEFRDPLEYLMKIRHIGTKTGICKIIPPKSWNPPFAVNMKEFSFTPRVQRLYELEAHSRIKLNFISRLYKFFRTQGGDKIRVPSIGGRFLDLYTLHKEVRSSGGYEKICIDHSWASVAEKLGYQS-RHASSIKTNYEKLLLAFDNLLYSELSADKRSNERKTGS-------------KRLRLLPCSDLEDIGTSTRRELRNLQFFGPGPKAAVPLLDTGRA----TASDRPDRHIDDYFCRICDRGDDEDNLLVCDTDACQACYHTYCLKPPLRSVPKCQWKCPECIRSVCLQPPEPYGFPQSSKSYSLHEFGVMADEFKSKYFGKPCTE-VSCAAVEHEFWRILQEYNDDVVVEYGADIHSSSKGSGFPTEARLPN----LVGTAQQLEDAKMYAISPWNLNILPLLDRSVLRFIKGNIDGMKIPWCYVGMVFSSFCWHIEDHWSYSINFNHWGEPKTWYGVSRFHAEDFERAMRKHAPELFDQSPDLLHHITTNMNPNILQGEGVPIYRTDQHCGEFVVTFPRAYHAGFNQGFNFAEAVNICLPDWLPIGRECVEHYSEIKRHCVFSNDELLCTLAEVAIGRCR--PEDILLVTNPYTPSKQRTSVARRGAQDLKSRLPPGCSTAGLDISAIAAVHQEFTILLTNERRLRDSVQAAGVKQMEKVRFDELPDDIRVCDVCLTTLFLSGVRCSCAAESPTQTKAQSTGVKRRTTDTAENSDHDSSFNDEDRPKSHMVCLKHVDQLCSSCAIASFTLKYHYTLEELEELETALAYRLKHFYAWRDRLASLLKSAETVDVKSKIERDPVTSSSSIIVKKESSDNMSDQASISEIWDTTITLNDLLEMLREGREAGYHTDDIFSEAESLVKRGNQLLVTCSSVIPWISAESETFDLDKTTNQLIRFQLRLPATFNVVTGSPTTASVVEGVKSTPSVSFVTLQHEMDLHNPRELDLTRLLESCKQLHPINLLQEPCVQSVKHFLDRLAEWRQVS 985
[Close]
BLAST of Lysine-specific demethylase vs. TrEMBL
Match: A0A183JBT5 (Uncharacterized protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS140 PE=4 SV=1)

HSP 1 Score: 778.474 bits (2009), Expect = 0.000e+0
Identity = 412/917 (44.93%), Postives = 552/917 (60.20%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHP-----STTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKN--GKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMS-----------------GLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCI-----------NEELKMAEDMKTEKKLKR----------------------IVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI------------------KAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDES 2607
            M   F+FV PPE PVF PT EEF+DPL Y+ +IRPI +K+GIC+I+PP  W PPF+VN+  F FTPR+Q+LYELEA SRIKLNF+++L +FV+LQG DK+++P+I+GR++DLY LHK V E GGY     N+LW  IA K+GY+S   A++++T+YEK++L +D ++S       Y S+ T   K   HP     S  + RKS+  + ID S    SNELK LQF G G       +  V  ED   S       + +Y C+ CG GD E  LL+CD + CQ CYH  CL PPL  +PK  WKC  CV  +       YGFP SS TY+L EFG  AD+FK+ YF +   + VPCS VE+EFWRILQ +NDD++VEYGADIHSS QGSGFPT   +KN  G  ++      +  A +Y++  WNLNILP+  +SVLRFI+GNIDGMK+PWCYVGMVFSSFCWHIEDHWS+SIN+ HWGEPKTWYGVS  +A+ FE AM+K A ELFD   DLLHHITT +NPNIL  EGVP+YRTDQ  G+FVVTFPRAYHAGFNQGFNFAEAVN C  +WL +GR C+EHYA++ RHCVFS+DELLCT+AE A+   + +P+E + +  P+ S                  L    +   LD      VH E   V++EER+ R  I +  ++   +  F+ + DD R C  C TT FLS   C CI           N   +  +D+ T  +  +                      +VCL+H++ +C  CP S +   Y +++EE+  L   L  RL  F++W   +                  K    +     + N      +L++L+++L EG   G+ + + +  ++ +L+RG++L  +C     +I  S +  K   S
Sbjct:    1 MPSDFSFVPPPEAPVFYPTPEEFEDPLGYLMKIRPICIKTGICKIVPPKCWNPPFAVNMKEFSFTPRIQRLYELEANSRIKLNFISRLYKFVQLQGGDKIRVPSISGRYLDLYALHKRVAEAGGYRQACDNQLWSDIAEKLGYQS-RHAHTIKTNYEKLLLSFDQVVS-------YPSRPT---KTTYHPRSRWSSYKRGRKSIGEEKIDYS---ASNELKNLQFFGPG-------RKAVVPEDGRPSNFKPEVNIDEYNCRVCGHGDDETNLLVCDTDSCQACYHLYCLDPPLRSIPKCQWKCPECVRAICCNPVDVYGFPQSSKTYSLQEFGVMADQFKSTYFKRPCTD-VPCSEVEREFWRILQEYNDDVVVEYGADIHSSSQGSGFPTKSMLKNLVGTASQ------LAEAKKYADSPWNLNILPLLDRSVLRFIKGNIDGMKIPWCYVGMVFSSFCWHIEDHWSYSINFNHWGEPKTWYGVSRLHADDFERAMKKHATELFDQAPDLLHHITTNVNPNILQAEGVPIYRTDQHCGEFVVTFPRAYHAGFNQGFNFAEAVNICLPDWLPIGRACIEHYAEIKRHCVFSNDELLCTLAEVAV--GNVLPEEILTLTNPVTSCTSNGECSDNPEPHISEKLPPGCSTSGLDIGAVAIVHQEFTCVLKEERRLRELIIQSGVSNSRKVRFDEMSDDARVCDFCLTTLFLSGVSCSCIYESNTSIQRLENPNDRSLDDLSTTARKHKMSDEPYGIIDESNEEEKRPPSHMVCLKHVSELCKKCPPSVFVLNYHYSIEELCSLEQSLADRLAHFYAWRNQLSFIIKPSDSNTFSSNHFMKQEANDNHVVVSNNSTSGTMTLEELEIKLTEGKAAGYHTDDIYNDAKAMLDRGKHLQQICVKLKPSIIGSGNTDKFKSS 887
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Match: kdm5c (lysine demethylase 5C [Source:NCBI gene;Acc:103035157])

HSP 1 Score: 678.707 bits (1750), Expect = 0.000e+0
Identity = 383/901 (42.51%), Postives = 516/901 (57.27%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSA-----------DHDSN----------IYISQSTVKPKPVLHPSTTKKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKDEVKLEDDLVSGP------------------------------------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLE-YGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNS 2580
            ME    FV PPECPVF P+ EEF DPL YI +IRPIA KSGIC+I PP DW PPF+V V+ F+FTPR+Q+L ELEA++R+KLN++ ++++F  +QGS  LKIPNI  R +DL+ L K+V E GG++ +   + W ++A K+GY       SL R+HYE+I+ P+++  S             +DS+          I + QS    +P    S  ++   LQ +P   E  +E + ELK+LQ  GAGP++       +D+ + +D  +  P                                    L+R     + +  +VC+ CG GD+++KLL+CD   C D YH  CL PPL+  PK +W+C  C+ E   KKP E +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VEKEFWR++ S  +D+ VEYGADIHS   GSGFP    + NGK   +N E +      Y+   WNLN++P+ ++SVL  I  +I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE+ E  M+K  PELF+   DLLH + TIMNPNILM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL C +A               P K               LD N+    H E+ + V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    E               R+VCL H  ++C SCPI +    YR+TL+E+  +L  L+VR + F SW   +K    +        E   +  +  L++   E AE  F   E   + R +L   Q   +  K  L   Q+S
Sbjct:    1 MEGGEEFVPPPECPVFEPSWEEFADPLGYIAKIRPIAEKSGICKIRPPPDWQPPFAVEVDNFRFTPRIQRLNELEAETRVKLNYLDRIAKFWEIQGSS-LKIPNIERRILDLFSLAKIVTEEGGFETVCKERRWARVAQKLGYPPGKNIGSLLRSHYERIVYPFEMFQSGASLPVQPCKPRPYDSDDVDKEYKPHSIPLRQSV---QPSKMSSYGRRANRLQPEPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLVARDKARKKDSDIPPPPPNLIVKSEVKKKEEDSADEFDSSAKDEPCTKMTMRLRRNLNNPQFVDSFVCRMCGRGDEDEKLLLCDG--CDDNYHTFCLLPPLTDPPKGNWRCPKCIAEC--KKPSEAFGFEQATREYTLQSFGEMADTFKADYFNMPVH-MVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFP----VNNGKRHLSNEEED------YARSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSVAAEKLEEVMKKLTPELFEFQPDLLHQLVTIMNPNILMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPTGRSCIEHYRRLRRYCVFSHEELTCKMAAC-------------PEK---------------LDLNLAAATHREMFIFVQEERKLRKALLEKGITEAEREAFELLPDDERQCDKCKTTCFLSALACTNCPE---------------RLVCLYHTQDLC-SCPIDKLYLRYRYTLDELLAMLHRLKVRAESFDSWANRVKEALEQ--------EEGNKIGIKDLEVLKEEAAERKFPDNELLQRLRSVLADIQRCKSRSKELLDGTQSS 830
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Match: kdm5a (lysine (K)-specific demethylase 5A [Source:ZFIN;Acc:ZDB-GENE-150114-1])

HSP 1 Score: 674.47 bits (1739), Expect = 0.000e+0
Identity = 366/856 (42.76%), Postives = 501/856 (58.53%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSAD-----------HDSNIYISQSTVK-----PKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKL 2598
            M  +  FV PPECPVF P+ E+F DPL YI +IRPIA KSGIC+I PP DW PPF+ +V  F+FTPRVQ+L ELEA +RIKLNF+ ++++F  LQGS KL+ P++  + +DLY L KLV   GG++ +   K W KIA++MG+ S   + +L R+H+++I+ PY++  S               S +++  + +      P  +     T     L        L   + E K LQ  G+ P++      E+     ++S  L+   +  Y+C  CG GD+ED+LL+CD   C D YH  CL PPL  VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP    +++GK  R  G+       +Y+N  WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV +  AEQ E  M+K APELFD+  DLLH + TIMNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL MGR CV HY +L R CVFSH+ELLC                             M++    LD  +   V+ EL  +++EE + R  +  M +   EQ +FE + DDER C  C+TTCFLSA  C C  +               R+VCL H  ++C+ CP++     YR+  EE   +L G++ R Q + +W   +    TE  A+   N+ D    L +L++ L +  +  +     F K R +++  +  ++V +  L   Q     S++
Sbjct:    1 MSMYAEFVPPPECPVFEPSWEDFSDPLGYISKIRPIAEKSGICKIRPPQDWQPPFACDVRNFRFTPRVQRLNELEALTRIKLNFLDQIAKFWELQGS-KLRFPHVEKKILDLYLLSKLVSAEGGFELVCKEKRWSKIASRMGFPSGKGSGTLLRSHFQRILYPYELFQSGASFTVSLPALDFQLSPVWLGAACLPFQHNPPLYLTFAQDTTGMFILLFLLFLFPLQRENKEPKTLQIFGSSPKVVGL---EIVPAGKVLSHYLRP--IDLYMCMACGRGDEEDRLLLCDG--CDDSYHTFCLIPPLQDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADHFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADIGSKDVGSGFP----VRDGK-RRLVGDEE-----EYANSGWNLNNMPVLEQSVLTHINADISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPAHAAEQLEAVMKKLAPELFDSQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPMGRQCVAHYRRLQRQCVFSHEELLC----------------------------KMAADPESLDVELAAAVYKELGDMMDEESRLRQAVSDMGVLSFEQEVFELVPDDERQCYKCKTTCFLSALTCPCSPD---------------RLVCLHHTADLCD-CPLTSKCLRYRYDQEEFPAMLYGVKSRAQSYETWAKRV----TEALAADHKNKKD----LIELKVLLEDAEDRKYPENNLFRKLREMVKEAETCSSVAQLLLSHKQRHKSSSRI 785
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Match: kdm5bb (lysine-specific demethylase 5B-B-like [Source:NCBI gene;Acc:103026437])

HSP 1 Score: 633.254 bits (1632), Expect = 0.000e+0
Identity = 337/787 (42.82%), Postives = 470/787 (59.72%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADHD-----------SNIYISQSTVKPKPVLHPSTTKKR-------KSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLV------SGPLKRK-----CLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F  PPECPVF P+ EEF DP  +I +IRPIA K+GIC++ PP DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV + GG++ +   + W KIA  MG+       S LR+HYE+++ PY++  S +H             ++   Q+T  P     PS   KR        S+Q + I  +L  T    K+L +      I    K E  +E  +V      + P ++K      +  YVC  CG+G+ ED+LL+CD   C D YH  CL PPL+ +PK  W+C  C+ +  SK    +GF  +   Y+L  FG+ AD FK++YF   +H +VP   VEKEFWR++++  +D+ VEYGADI S   GSGFP    I+ G   R    P+ +   +Y +  WNLN + +   SVL  +  +I GM +PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELF++  DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY  LHR+CVFSHDE++C                            NM++    LD  +  +VH ++ L++ EER  R +I K+ + + E   ++ L+DDER C  C+TTC+LSA  C C   E                VCL H  ++C SCPIS +T  YRFTL+++  +++ ++ R + +  W + +
Sbjct:    9 FQPPPECPVFEPSWEEFADPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLYQLNKLVADEGGFELVCKERRWTKIAMTMGFAPGKAVGSHLRSHYERVLYPYNLFQSGNHSLPESDEKEYKPHDLVQRQNTQVPPDASTPSRRAKRMKAEVKLNSVQFNFISIALFTTEVVTKQL-YREKLKEIPIQIKQE-PVESKVVQPEPEKTKPRQKKNTPPPPVDLYVCLVCGNGNDEDRLLLCDG--CDDSYHTFCLIPPLTDIPKGDWRCPKCLAQECSKPQEAFGFEQARRDYSLKAFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVRTIEEDVTVEYGADIASKEFGSGFP----IRGG---RFKVAPHDE---KYLSCGWNLNNMAMMDPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAPELFESQPDLLHQLVTIMNPNTLMSYGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRLLHRYCVFSHDEMIC----------------------------NMAAKANKLDVVLASSVHKDMVLMINEERDLRDQIRKLGVVQCELFEYDLLQDDERQCVKCRTTCYLSALTCPCRPGEQ---------------VCLHHARHLC-SCPISNYTLKYRFTLDDLYPMMNAVKQRAESYDVWASHV 735
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Match: kdm5bb (lysine-specific demethylase 5B-B-like [Source:NCBI gene;Acc:103026437])

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 331/801 (41.32%), Postives = 460/801 (57.43%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSA------------DHDSNIYIS------QSTVKPKPVLHPSTTKKRKSLQSD-------PIDESLMETSNELKRLQFSGAG------------------PRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F  PPECPVF P+ EEF DP  +I +IRPIA K+GIC++ PP DW PPF+ +V+   FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV + GG++ +   + W KIA  MG+       S LR+HYE+++ PY++  S             + D   Y        Q+T  P     PS   KR   +S             + E    L+R   S                      ++     ++ K      + P     +  YVC  CG+G+ ED+LL+CD   C D YH  CL PPL+ +PK  W+C  C+ +  SK    +GF  +   Y+L  FG+ AD FK++YF   +H +VP   VEKEFWR++++  +D+ VEYGADI S   GSGFP    I+ G   R    P+ +   +Y +  WNLN + +   SVL  +  +I GM +PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELF++  DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY  LHR+CVFSHDE++C                            NM++    LD  +  +VH ++ L++ EER  R +I K+ + + E   ++ L+DDER C  C+TTC+LSA  C C   E                VCL H  ++C SCPIS +T  YRFTL+++  +++ ++ R + +  W + +
Sbjct:    9 FQPPPECPVFEPSWEEFADPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDVDRLHFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLYQLNKLVADEGGFELVCKERRWTKIAMTMGFAPGKAVGSHLRSHYERVLYPYNLFQSGANLLFIQNHSLPESDEKEYKPHDLVQRQNTQVPPDASTPSRRAKRMKAESGCGKSEACAAGGEVCENKPNLRRRMGSFVAKSEPVKEIPIQIKQEPVESKVVQPEPEKTKPRQKKNTPPPPVSVVDLYVCLVCGNGNDEDRLLLCDG--CDDSYHTFCLIPPLTDIPKGDWRCPKCLAQECSKPQEAFGFEQARRDYSLKAFGEMADSFKSDYFNMPVH-MVPTELVEKEFWRLVRTIEEDVTVEYGADIASKEFGSGFP----IRGG---RFKVAPHDE---KYLSCGWNLNNMAMMDPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLEAVMKKLAPELFESQPDLLHQLVTIMNPNTLMSYGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRLLHRYCVFSHDEMIC----------------------------NMAAKANKLDVVLASSVHKDMVLMINEERDLRDQIRKLGVVQCELFEYDLLQDDERQCVKCRTTCYLSALTCPCRPGEQ---------------VCLHHARHLC-SCPISNYTLKYRFTLDDLYPMMNAVKQRAESYDVWASHV 751
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Match: kdm5ba (lysine (K)-specific demethylase 5Ba [Source:ZFIN;Acc:ZDB-GENE-030131-5379])

HSP 1 Score: 600.127 bits (1546), Expect = 0.000e+0
Identity = 316/760 (41.58%), Postives = 441/760 (58.03%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLM--ETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F+ PPECPVF P+ EEF DP  +I +IR IA  +GIC+I PP  W PPF+ +V+   FTPR+Q+L ELEAQ+R++LNF+ ++++F  LQG   LKIP++  + +DLY+L+K+V E GG++ +   + W +I+T++G+       S LR+HYE+++ PY            Y+ Q     KP L   T  K       P  +S+   ET+   +R + +    R   + + E       +   +    +  Y+C  CG G  ED+LL+CD   C D YH  CL PPL  VPK  W+C  C+ +   K  + +GF  +S  YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    +KNG       E +      Y    WNLN +P+   SVL  I  +I GMK+PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E+ M+K APELF++  DLLH + TIMNPN+LM+ GVP+YRT+Q           +YH+GFNQGFNFAEAVNFC  +W+S+GR CV HY  L+R+CVFSHDE++C IA  A    DN+                    D+ L   I++ + A    ++EEE++ R +  K+ +   +Q  +E L D+ER C  C+TTCFLSA  C C   +L               VCL H+ ++C SC  S +T  Y++TL  ++++   +  R   +  W + +
Sbjct:   14 FIPPPECPVFEPSWEEFSDPFGFINKIRSIAENTGICKIRPPPGWQPPFACDVDRLHFTPRIQRLNELEAQTRVRLNFLDQIAKFWELQGC-TLKIPHVERKSLDLYQLYKVVSEEGGFEQVCKERKWTQISTRLGFAPGKAVGSHLRSHYERVLYPY------------YLFQIGTSQKPTLTNDTKDKEYKSHDLPQRQSVQPAETTTIARRAKRTEG--RCVKTEQGEPCENRPNLRRRMGSCVVEQYICLVCGGGGDEDRLLLCDG--CDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECGKPQVAFGFEQASRDYTLRSFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKDFGSGFP----VKNGSFKVTPDEEH------YVTSGWNLNNMPVLDSSVLTHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEQLEMVMKKLAPELFESQPDLLHQLVTIMNPNLLMEHGVPIYRTNQ-----------SYHSGFNQGFNFAEAVNFCTVDWMSLGRQCVAHYRSLNRYCVFSHDEMVCNIAAKA----DNL--------------------DLVLACAIQKDMSA----MMEEEKELRERAYKLGVWHSQQVDYEELPDEERQCIKCRTTCFLSAITCPCSPTQL---------------VCLHHLQDLC-SCACSNYTLNYKYTLGLLNQMFKSVAGRAVSYDDWASKV 690
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Match: kdm5c (lysine (K)-specific demethylase 5C [Source:ZFIN;Acc:ZDB-GENE-060810-94])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 360/820 (43.90%), Postives = 479/820 (58.41%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIMLSADHDSNIYISQ-------STVKPKPV-----LHPSTT----KKRKSLQSDP-IDESLMETSNELKRLQFSGAGPRIYA---STKDEV--------------KLEDDLV-------------------------SGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHW-GEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKA 2376
            FV+PPECPVF PT EEF DP+ YI +IRP A K+GIC+I PP DW PPF+V+V+ F+FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQGS  LKIP +  + +DLY L K+V E GG++     + W ++A KMGY +   A S LR+HYE+I+ PYD+  S    S +   Q          KP  +     L P  T    ++ K L+ +P + ++ +    EL+R+Q   +G R  A   + KD++               LED                            +G L  + +  YVC  CG GD+EDKLL+CD   C D YH  CL PPL  VPK  W+C  CV E  SK    +GF  ++  YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADIHS   GSGFP        +  R    P  +   +Y+   WNLN +P+  +SVL  I  +I GMKVPW YVGM FS+FCWHIEDHWS+SINYLHW GEPKTWYGV +  AE  E  M+K APELF+   DLLH + TIMNPN+LM  GVPV RT+Q AG+FV+TFPR+YH+GFNQG+NFAEAVNFC A+WL  GR CVEHY +LHR+CVFSHDEL+C +A     E D                         LD  +  +VH ++ +++EEER+ R  +E+      E+  FE + DDER C  C+TTCFLSA  C C                  R+VCL H +++C  CP       YR+T+EE+  +L+ L+ R   F  W + ++A
Sbjct:    8 FVAPPECPVFVPTWEEFSDPMGYIAKIRPSAEKTGICKIRPPPDWQPPFAVDVDKFRFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGS-TLKIPIVERKILDLYMLSKVVSEEGGFETSCKERKWSRVAAKMGYPAGKGAGSLLRSHYERILYPYDLFQSGVSLSGLSKPQFESNDKDKEYKPHSIPLRQSLQPPKTDSYGRRAKRLKQEPDVVDTEVPKLPELRRMQAYCSGMRASAHVSANKDKLVKCLKLHCPSYPSTSLEDSFSGGSCWVLSKDNTLLQPCTSLSMRQRTGALSAQFIEMYVCLVCGRGDEEDKLLLCDG--CDDSYHTFCLIPPLQDVPKGDWRCPKCVAEECSKPQEAFGFEQATKEYTLQSFGEMADTFKSDYFSMPVH-MVPPELVEKEFWRLVSTIEEDVTVEYGADIHSGEFGSGFPV-------RGTRRKLTPEEE---EYARAGWNLNNMPVLAESVLAQINADISGMKVPWLYVGMCFSAFCWHIEDHWSYSINYLHWSGEPKTWYGVPAHAAESLEEVMKKLAPELFEAQPDLLHQLVTIMNPNLLMAHGVPVVRTNQCAGEFVITFPRSYHSGFNQGYNFAEAVNFCTADWLPTGRQCVEHYRRLHRYCVFSHDELICKMAA----EPDG------------------------LDLPMAASVHRDMTVMMEEERRLRKSVEQRGTCDSEREAFELIPDDERQCDFCKTTCFLSALTCSC---------------SPTRLVCLHHADDLCR-CPPQRQCLRYRYTMEELPDMLAKLKARADCFDDWVSRVRA 769
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Match: kdm5c (lysine (K)-specific demethylase 5C [Source:ZFIN;Acc:ZDB-GENE-060810-94])

HSP 1 Score: 643.654 bits (1659), Expect = 0.000e+0
Identity = 390/1011 (38.58%), Postives = 535/1011 (52.92%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLH-PSTTKKRKSLQ-----------------SDPIDESLMETSNELKRLQFSGAGPRIYA----STKDEVKLE----------------------DDLVSGP----------------------LKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDES-----------DEVRLHVPKSVLIDCV------------RENGSVEIKNINVASLTEENLAHMNQTLIR----FPLKLP-CDQFEQMVARLLQWRQDSHTLMALNMNN 2847
            FV PPECPVF+PT EEF DPL YI +IRPI  K+GIC+I PP +W PPF+V+V+ F+FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQGS  LKIP +  + +DLY L K+V E GG++ +  ++ W ++A KMGY +     SL R HYE+I+ P+++  S    S I   +     K   + P +   R+SLQ                  DPID  +  +++EL++LQ  GAGP++      + KD    E                      DD+ + P                        R  +  Y C  CG GD E KLL+CD   C D YH  CL PPL  VPK  W+C  CV +  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++    +D+ VEYGAD+ +   GSGFP    +KNGK              +Y++  WNLN +P+  +S+L  I G+I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYGV +  AE  E  MR  APELF    DLLH + TIMNPNILM   VPV RT+Q  G+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL MGR CVEHY  + R+CVFSH+ELLC +A            E   +  P+ S +     +I +D                  R+ R +  +M ++K E   FE L DDER C  C+TTC+LSA  C C                  R+VCL HI ++C  CP       YR+TL+E+  +L  L+ R + F +W   ++    E        E  K+  L  L+  L E     F   E  ++   +L   +   + C    + + NS +C + D+S           +E +  V +   + C             R  G  +   + + +  + +L  M + L       P+ LP  +Q EQ V R  +W ++ HT +A ++++
Sbjct:    9 FVPPPECPVFQPTWEEFGDPLAYIAKIRPIGEKTGICKIRPPPEWQPPFAVDVDNFRFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGS-TLKIPILERKLLDLYMLSKVVAEEGGFEIVCKDRKWSRVAAKMGYMTGKAVGSLLRVHYERILYPHNLFQSGVSLSCIAKPEYEPDEKDQEYKPHSIPLRQSLQHGKMNCAGRRANRMKTEPDPIDADV-SSNSELRKLQIFGAGPKMAGLGLLTGKDRNGKESVLGDPKYAVSCNLAEGGERGLDDVKALPSMDIQCPEPEPEPQTAIIPEKYFLRMKVDLYECLVCGRGDDEAKLLLCDG--CDDSYHTFCLIPPLQDVPKGDWRCPKCVAQECSKPQEAFGFEQAKRVYTLRSFGEMADVFKSDYFNMPVH-MVPTELVEKEFWRLVSCIEEDVSVEYGADVQAKEYGSGFP----VKNGKKK------LSKEEEEYTSSGWNLNNMPVLPQSLLGHIDGDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPAYAAESLENVMRTLAPELFLAQPDLLHQLVTIMNPNILMAHDVPVVRTNQCPGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPMGRRCVEHYRLMRRYCVFSHEELLCRMA-----------CETEGLALPMASAIG-RELEIAIDEE----------------RKLRREAWEMGVSKSEPFEFELLADDERQCHFCKTTCYLSAIACPCCP---------------GRLVCLYHIRDLCR-CPTQHKILRYRYTLDELPPMLHKLKSRAEIFDAWAEKVRRALEE--------ENGKKSDLSALKALLEESETHDFP--ESSLRQNLMLLVLE--ADQCASMAQDLMNSRNCVRRDKSGATEEQVMLSLEEFKTFVNRLEKLPCTVNYMNEIKELLERVEGFRDAVQLLLVAEDKPDLVRMQELLKEAEHLAPVHLPEKEQLEQRVQR-ERWLEEVHTALASSLSS 947
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Match: jarid2a (jumonji, AT rich interactive domain 2a [Source:ZFIN;Acc:ZDB-GENE-061218-1])

HSP 1 Score: 139.813 bits (351), Expect = 5.202e-34
Identity = 113/435 (25.98%), Postives = 196/435 (45.06%), Query Frame = 1 
Query: 1045 TYTLYEFGKSADKFKANYFGKELHELVPCSS-VEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCV---FSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQ------CINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLL 2319
            + +L  F ++A    + +  KE     P +S +E+++W I+Q+ +  + V  G  + ++   SGFP               EP       +S   WNL +LP    SVLR + G + G+ VPW  VGMVFS++ W  + H+  SI+YLH G  K WY + +   ++ +  +         +  ++L +  ++++P +L   GV VYRT Q++GQFVVTFP ++ +  + G++ +E + F PA+WL +G    E   ++ R C+   F  D+LL   A    LE+ N     +    PL+  L         + N+RR +H                   +   +     +  ++  ER C  C+  C+LS    +      C++  L   E+  + ++LK                      +YR+  E+MD L+
Sbjct:  264 SVSLTAFYRAARNLLSTHCSKE-----PSASLIEQKYWEIVQNQDMHVSVHCG-KVDTNFVSSGFPI-----------GRSEP-------FSRHSWNLTMLPSNPGSVLRHL-GALSGVTVPWLNVGMVFSTWVWARDPHYLPSIDYLHTGADKIWYCIPASQKDKLDKVVHSLLQANGKSGLEMLQN--SMVSPEVLSHAGVSVYRTVQRSGQFVVTFPGSFTSSVSCGYSVSETITFAPADWLPLGCRAAE---EVKRRCIPNMFPVDKLLYLTA-VGELEKGNA--AALAHVGPLLGQLRDR------ELNLRRRLHVRGLRSWARYGCQDAHHPGVAEVRKRPRKWLPIESAERRCLTCRQLCYLSMVVEESENVVFCLHCALARTEEQGSCRRLK---------------------LMYRYDQEQMDSLV 638

HSP 2 Score: 69.3218 bits (168), Expect = 4.724e-12
Identity = 41/140 (29.29%), Postives = 68/140 (48.57%), Query Frame = 1 
Query:  112 PECPVFRPTKEEFKDPLEYIEQIRPIAV--KSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQ 525
            PE PV  PT  EF DPL Y+E +R  A   ++G CR+ PP  W P   ++ +  +F  RVQ +++L  +       +  + + +  QG    ++P I G  +DL  L  L+   GG   +   + W ++A  +     +Q
Sbjct:    3 PEVPVLYPTAREFLDPLAYVEGVRSRAGVEEAGACRVAPPTCWRPECRLS-DDMRFVTRVQHVHKLGRRWGPNEMRLACIRKHLLRQGIALEELPLIGGCELDLASLSVLMESLGGMQQLRDARAWQRLADALRVPRAAQ 141
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010019.1 (pep scaffold:Pmarinus_7.0:GL481681:6200:13508:-1 gene:ENSPMAG00000009067.1 transcript:ENSPMAT00000010019.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.633 bits (174), Expect = 1.823e-13
Identity = 41/132 (31.06%), Postives = 67/132 (50.76%), Query Frame = 1 
Query:  328 NFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMG--YKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETS 717
            NF+ +L  F+R + +   +IPN+  + VDL+ + + V E GGY+ + + +LW +I   +G    STS A   R HYE++ILPY+  +  + D            KP+  P   +KR    S   D+   + S
Sbjct:    8 NFLRELHGFMRTRKTPIGRIPNLGFKQVDLWVMFRAVQELGGYEAVTSQRLWKQIYDTLGGNRGSTSAATCTRRHYERLILPYERHVKGEED------------KPLPPPVKPRKRSDASSSSGDKKKQQQS 127
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005177.1 (pep scaffold:Pmarinus_7.0:GL477523:31773:39538:1 gene:ENSPMAG00000004708.1 transcript:ENSPMAT00000005177.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 4.652e-12
Identity = 31/75 (41.33%), Postives = 44/75 (58.67%), Query Frame = 1 
Query: 1321 ELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFE 1545
            E WN+  L      V +     IDG+  P+ Y GM  ++F WH ED   +SINYLH+GEPK+WY +  E+ ++ E
Sbjct:  147 EDWNIGHLNTVLDVVEQDSGITIDGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLE 221
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Yeast
Match: JHD2 (JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p methyltransferase; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription in opposition to programmed global transcriptional quiescence; regulates rDNA silencing [Source:SGD;Acc:S000003880])

HSP 1 Score: 273.478 bits (698), Expect = 3.149e-78
Identity = 183/615 (29.76%), Postives = 299/615 (48.62%), Query Frame = 1 
Query:  115 ECPVFRPTKEEFKDPLEYIE--QIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVR-LQGSDKLKI--PNINGRHVDLYK----LHKLVHENGGYDHIIANKLWLKIAT-----KMGYKSTSQAYS----LRTHYEKIILPYDIM--LSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPC-----SSVEKEFWRILQSFNDDII--VEYGADIHSSHQG--SGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNI--LMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAE 1866
            E P   PT++EFK+P++Y+    I+ + V+ G+ +++PP+ + PP S+++  F F PR+Q L  L+ ++R +L FM +L+ F R ++   KL +  P     + D       L K V+    +  +I +   L   T     K+ ++  SQ        RT  +K  +P  ++  +   + ++ YI          LH        +L +D   +SL+    +   L     GP   + +  E   EDD            D  C  C   +   + ++CD+  C   +H  CL+PPL +VP   W C+ C++         YGF   +  Y+L EF +        Y  ++   L+P        +E+ FW ++       +  V+YGADIH+   G  +GFPT E I        NG+  +D  ++Y +   NL  LP+   S+L   + NI GM +PW Y+G +FS+FCWH+ED ++ S NY H G+PK WY +      +F   +   +P+LF    DLLH + T+++P      K G+PVY+  Q+  ++++TFP+ YHAGFN G+NF EAVNF    WL  G   +  Y    + CVF   +L+  + +
Sbjct:    3 EIPALYPTEQEFKNPIDYLSNPHIKRLGVRYGMVKVVPPNGFCPPLSIDMENFTFQPRIQNLENLDLKNRCRLFFMKQLNNFKRSVKDPSKLILREPYTIVEYSDSTHASEILKKKVYFYDVFSELIKDNRTLTDTTQSFRRKLKFRDISQLRGDISLWRTISKKFNVPIGLLKEIFEKYIASYYI---------FLHSLNENVHTALHADQYPKSLLSDDEDDFDL-----GPDSNSGSDFE---EDD------------DDACIVCRKTNDPKRTILCDS--CDKPFHIYCLSPPLERVPSGDWICNTCIV-----GNGYYGFTQDTHDYSLPEFQE--------YCKRQNSRLLPARKLSIDELEEMFWSLVTKNRRSSLTTVKYGADIHNELPGQITGFPTREFIPKNI----NGDELIDY-LKYCDHPMNLTNLPMAHNSLLPLFKRNISGMTIPWIYIGSLFSTFCWHMEDQYTLSANYQHEGDPKVWYSIPESGCTKFNDLLNDMSPDLFIKQPDLLHQLVTLISPYDPNFKKSGIPVYKAVQKPNEYIITFPKCYHAGFNTGYNFNEAVNFTIDFWLPYGFGAITDYKLTQKACVFDMFDLMINVLD 568
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Yeast
Match: RPH1 (JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication [Source:SGD;Acc:S000000971])

HSP 1 Score: 122.865 bits (307), Expect = 8.665e-29
Identity = 56/155 (36.13%), Postives = 89/155 (57.42%), Query Frame = 1 
Query: 1324 LWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGR 1788
            +WN+  LP    ++L  +   + G+   + Y G+  +SF WH+ED   +SINY+H+G PK WY +  E+  +F   M++Q PE   N  + L H   + +P +L + G+         G+F++T+P  YHAGFN G+N AE+VNF    WL +G+
Sbjct:  198 VWNVAKLP----NILDHMETKVPGVNDSYLYAGLWKASFSWHLEDQDLYSINYIHFGAPKQWYSIPQEDRFKFYKFMQEQFPEEAKNCPEFLRHKMFLASPKLLQENGIRCNEIVHHEGEFMITYPYGYHAGFNYGYNLAESVNFALEEWLPIGK 348
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Yeast
Match: GIS1 (Histone demethylase and transcription factor; regulates genes during nutrient limitation; activity modulated by proteasome-mediated proteolysis; has JmjC and JmjN domain in N-terminus that interact, promoting stability and proper transcriptional activity; contains two transactivating domains downstream of Jmj domains and a C-terminal DNA binding domain; relocalizes to the cytosol in response to hypoxia; GIS1 has a paralog, RPH1, that arose from the whole genome duplication [Source:SGD;Acc:S000002503])

HSP 1 Score: 92.0485 bits (227), Expect = 3.997e-19
Identity = 50/149 (33.56%), Postives = 73/149 (48.99%), Query Frame = 1 
Query: 1312 YSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNF 1758
            Y   LWNLN LP +  S  R +              G     F WH+++    SINYLH+G PK WY + S N +QF   + K+     +N    + H   I +P+ L K  +   R  Q   +F++TFP   ++GFN G+NF E++ F
Sbjct:  171 YDLTLWNLNNLPDSINSSNRRL------------LTGQSKCIFPWHLDEQNKCSINYLHFGAPKQWYSIPSANTDQFLKILSKEPSSNKENCPAFIRHQNIITSPDFLRKNNIKFNRVVQFQHEFIITFPYCMYSGFNYGYNFGESIEF 307
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Yeast
Match: ECM5 (Subunit of the Snt2C complex; physically associates with Snt2p and Rpd3p; along with Snt2p, recruits Rpd3p to a small number of promoters; also colocalizes with Snt2p, independently of Rpd3p, to promoters of stress response genes in response to oxidative stress; contains ATP/GTP-binding site motif A; null mutant exhibits increased cellular volume, large drooping buds with elongated necks; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000004788])

HSP 1 Score: 88.9669 bits (219), Expect = 4.612e-18
Identity = 56/177 (31.64%), Postives = 90/177 (50.85%), Query Frame = 1 
Query:   64 SKYIHEMEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICR--IIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQF-VRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKS---TSQAYSLRTHYEKIILPYDI 576
            ++  HE    F  +SP   P F   K+E  DP+++ E +  +    G  +  IIP  D     +V+V+   F  R Q     E Q    ++F  KL  F  +++ S   +IP+I+ R +DLY+L   V   GG++ +   KLW +I  ++GY     +S + SLR+ Y KI+L +DI
Sbjct:  100 ARVFHEKTGLFYQISPHSIPTFILAKKELPDPIKFYELVEDLGSVYGCVKLKIIPDADKFTQLNVDVDRLWFKARKQFFNSNEFQRTKIVDFYAKLYNFHNKIKKSTLTRIPSIDKRTLDLYRLRSCVKLRGGFNAVCEKKLWAQIGRELGYSGRIMSSLSTSLRSAYAKILLDFDI 276

HSP 2 Score: 58.9214 bits (141), Expect = 6.451e-9
Identity = 60/298 (20.13%), Postives = 109/298 (36.58%), Query Frame = 1 
Query: 1051 TLYEFGKSADKFKANY---FGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRK---------QAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRT-----------DQQAGQ---------------------------------FVVTFPRAYHAGFNQGFNFAEAVNFCPANWL 1776
            +L  F     KF ++Y   F K  H  +P    E+ ++ +L     D  ++ G  +  S +  G               N   N   AI+   + WNL+ +P+ + S+L+ +  ++         +GM+FS   W + DH+  SI++ H G  K  Y ++ ++ E+FE  + +           P    + ++L   I T    + L  E    Y             D+ AG                                  ++  FP+A+      GF  ++   F P++WL
Sbjct:  404 SLAVFTAIVAKFGSSYPDLFAK--HTTLPQKEFERLYFHLLSEHFIDFEIDTGLGLPCSMRSPG---------------NNSSNEKFAIKNILDQWNLDNIPLNELSLLQHLDLDMANFTRTTYDIGMLFSCQGWSVSDHFLPSIDFNHLGSTKLVYSIAPKDMEKFEALIARGKSEWDTIQSRPRYSTSDDELKSFIETDFYKSFLDAEQSADYSNTGDNSKNSFPEDKIAGNTLHDGSQSDFIFEPNFILANGIKLYKTTQEQGSYIFKFPKAFTCSIGSGFYLSQNAKFAPSSWL 684
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Match: EDO34883 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN37])

HSP 1 Score: 298.516 bits (763), Expect = 1.435e-83
Identity = 158/385 (41.04%), Postives = 223/385 (57.92%), Query Frame = 1 
Query: 1396 MKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQT-LFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNV 2547
            MKVPW YVGM FSSFCWH EDHWS+SINY+HWGEPKTWYG+  + AE+FE+AM++ APELF+   DLLH + TI++PN L  +GVPV RT+Q AG+FV+TFPRAYHAGFNQG+N AEAVNF  ++WL +GR C+ HY ++ R+ VFSH+EL+C +A          PD                     LD ++ + V+ E+  +VE E + R  + +    + E+   FE L DDER C IC+TTCFLSA  C+C  E               R+ CL   + +C +C  S+ T  YR+TL+E+  +L  L+ R + F +W + +K               D + S+ +L+  +    +  F  C+     +G +   +   +V
Sbjct:    1 MKVPWVYVGMCFSSFCWHNEDHWSYSINYMHWGEPKTWYGIPGDAAEEFEMAMKEAAPELFEAQPDLLHQLVTIISPNALTAKGVPVVRTNQHAGEFVITFPRAYHAGFNQGYNLAEAVNFATSDWLPIGRHCINHYREMTRNPVFSHEELVCKMAAD--------PD--------------------GLDLDLAKAVYDEMLAIVETETKRRNTLLENGAQEFERAEAFELLPDDERQCQICKTTCFLSAVTCKCSEE---------------RLTCLDCASELC-ACRPSDKTLRYRYTLKELPSMLYRLKQRAESFDNWASGVKR---------ILELADNKVSVAELKELVTTAEQSQFPECDLLTLLKGAVSEAERCASV 332
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Match: EDO46479 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ11])

HSP 1 Score: 134.035 bits (336), Expect = 1.944e-31
Identity = 70/216 (32.41%), Postives = 112/216 (51.85%), Query Frame = 1 
Query: 1129 CSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWL 1776
             + VE+E+WRI+QS +  + VE    + +  QGS FP           +NN          YS   WNLN+ P  K S+LR    N++G+ +PW  +GMVFS+  W +     ++++YLH    K WYGV   +  +F  ++R    ++ D  + +      +   N+L + G+ V R  Q+ GQFVV  P+AYH   + G++ +E+V F   +WL
Sbjct: 1114 AADVEREYWRIIQSRDRYVSVEQ-CRVDTGEQGSCFPV---------GKNN---------PYSKSGWNLNVFPRLKGSILRHA-ANVEGLSLPWLSIGMVFSTDRWKVHPLQMYTLSYLHTSADKVWYGVPEADVAKFPGSLRPSQADIHDGKDSM------VSPSNLLRETGLTVTRLVQKQGQFVVVSPKAYHCSISSGYSISESVAFAFPDWL 1303

HSP 2 Score: 85.5001 bits (210), Expect = 1.280e-16
Identity = 58/169 (34.32%), Postives = 94/169 (55.62%), Query Frame = 1 
Query:  121 PVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQ---SRIKLNFMTKLSQFVRLQGS-DKLK-IPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAY--SLRTHYEKIILPYDIMLSADHDSNI 606
            PV RPT+EEFKDP+++++ ++P   K GIC I PP+ W P   +  N  +F  + Q ++ L+ +     IKL  + K    ++ QG+ + LK +P I G  VDL ++ +++ E GG   +I  K W K+A  +    T+Q     L+  Y + +L YD +LS D  S +
Sbjct:  898 PVLRPTEEEFKDPIKFLQSVQPSLKKYGICLIEPPESWKPESQLPPN-LRFNSQRQLVHRLKERWGPVEIKLACIEK---HLKQQGNPEPLKQMPQIGGMDVDLLEVSRIMAEFGGMQKVIDAKKWGKVADTLRIPKTAQDRIGKLQDVYCRFLLSYD-LLSQDEKSTL 1061
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Match: EDO45584 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSL0])

HSP 1 Score: 58.151 bits (139), Expect = 5.661e-10
Identity = 34/105 (32.38%), Postives = 60/105 (57.14%), Query Frame = 1 
Query:  265 FQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKS--TSQAYSLRTHYEKIILPYD 573
            + F  + ++LYEL  +   K  F+  L  F++ +G+   ++P +  + +DLYKL +LV + GG   +I  K+W +I   +   +  TS A++LRT Y K + PY+
Sbjct:    1 WTFEEQFKQLYELGDEPDRK-TFLDDLFAFMQKRGTPVNRVPIMAKQTLDLYKLFRLVVDKGGLVEVINKKIWREIIKGLNLPASVTSAAFTLRTQYMKYLYPYE 104
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Match: EDO39057 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SB54])

HSP 1 Score: 59.3066 bits (142), Expect = 1.252e-9
Identity = 26/73 (35.62%), Postives = 42/73 (57.53%), Query Frame = 1 
Query: 1327 WNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFE 1545
            WN++ L      +    +  ++G+  P+ Y GM  ++F WH ED   +SINY+H+G PKTWY V  E+  + +
Sbjct:  138 WNVSRLQTILDLINTEYKVKVEGVNTPYLYFGMWKATFAWHTEDMDLYSINYIHYGAPKTWYVVPPEHGPRLK 210
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Match: EDO49241 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGW2])

HSP 1 Score: 54.299 bits (129), Expect = 7.036e-9
Identity = 25/83 (30.12%), Postives = 48/83 (57.83%), Query Frame = 1 
Query:  331 FMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKS--TSQAYSLRTHYEKIILPYD 573
            FM  L +F++ + +   KIP +  + V+L+ ++      GGY+ + + +LW ++   +G  +  TS A   R HYE+++LPY+
Sbjct:    5 FMRLLREFMKSRETPISKIPALGFKRVNLWTMYNTTQRLGGYEMVTSKRLWRQVYDALGGSTTITSAATYTRRHYERLLLPYE 87
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Match: kdm5c (lysine demethylase 5C [Source:NCBI gene;Acc:101167366])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 394/955 (41.26%), Postives = 540/955 (56.54%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSA--------------DHDS-----NIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYA---------------------------STKDEVKLEDDLVS--------GP-------LKR-----KCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLE-YGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPAS---------FTANEPDKRWSLDQLQMRLN----EGAECGFDSCEE----FVKSRGLLERGQNLTNVCKHW----LKAIQNSDDCSK----------LDESDEVRLHVPKSVLIDCVRENG 2667
            F+ PPECPVF P+ EEFKDPL YI +IRPIA KSGIC+I PP DW PPFSV +++F+FTPRVQ+L ELEA++R+KLN++ ++++F  +QGS  LKIP+I  R +DL+ L K+V + GG++ +  ++ W +IA ++GY       SL R+HYE+I+ PY++  S               D D      +I + QS V+P  +        R     +P +E + E + ELK+LQ  GAGP++                               K+E+K E D  S        GP       L+R     + +  YVC+ CG GD +DKLL+C    C D +H  CL PPL+  PK +W+C  CV E   KKP E +GF  ++  YTL  FG+ AD FKA+YF   +H +VP   VE+EFWR++ S  +D+ VEYGADIHS   GSGFP    + NGK      E       +Y+   WNLN++P+ ++S+L  I G+I GMKVPW YVGMVFS+FCWHIEDHWS+SINYLHWGEPKTWYGV S  AE+ E  M+K  PELF+   DLLH + TIMNPNILM  GVPV RT+Q AG+FV+TFPRAYH+GFNQG+NFAEAVNFC A+WL  GR C+EHY +L R+CVFSH+EL C +A +             P K               LD N+    H E+ ++V+EER+ R  + +  +T+ E+  FE L DDER C  C+TTCFLSA  C    E+L               VCL H  ++CN CP  +    YR+TL+E+  +L  L+VR + F SW   +K    +   S               +K++  ++L  +LN    +   C   S +E    F + + L+E  QNL  V   +    ++A  NS +             L+E   + + VP+  L+  ++E G
Sbjct:    6 FIPPPECPVFEPSWEEFKDPLGYIAKIRPIAEKSGICKIRPPPDWQPPFSVELDSFRFTPRVQRLNELEAETRVKLNYLDRIARFWEIQGSS-LKIPHIERRILDLFSLSKIVTDEGGFEMVCKDRRWARIAQRLGYPPGKNIGSLLRSHYERIVYPYEMFQSGSCLLPCKPKHYDGEDVDKEYKPHSIPLRQS-VQPSKISSYGRRANRCQPDPEPTEEDI-EKNPELKKLQIYGAGPKMMGLGLVARDKSIRKKGDAYNPPPPPPTVIVKKEELKEEVDKKSEGKREHMEGPCTKMTMRLRRNPNNPQSVDSYVCRMCGRGDDDDKLLMCYG--CDDNFHTYCLLPPLADPPKSNWRCPKCVAEC--KKPTEAFGFEQATREYTLQSFGEMADSFKADYFNMPVH-MVPPELVEREFWRLVSSIEEDVTVEYGADIHSKEFGSGFP----MNNGKKILTEEEE------EYARCGWNLNVMPVLEQSLLCHINGDISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSVAAERLEEVMKKLTPELFEFQPDLLHQLVTIMNPNILMAHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRSCIEHYRRLRRYCVFSHEELTCKMAAS-------------PEK---------------LDLNLAAATHREMFIIVQEERKLRKNLMERGITEAEREAFELLPDDERQCDKCKTTCFLSALACSNCPEQL---------------VCLYHTQDLCN-CPTEKLYLRYRYTLDELLAMLHRLKVRSESFDSWANRVKEALEQEDGSKIDIEDLDKLMLEAAEKKFPDNELLRKLNTVFKDIGSCRQKSADERKVTFAELKSLVETMQNLPCVMDQFEEVQVRANPNSAEGGDSPPPEQLQTLLNEGSTLPVVVPECDLLQGLKEQG 898
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Match: kdm5a (lysine demethylase 5A [Source:NCBI gene;Acc:101161451])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 360/874 (41.19%), Postives = 500/874 (57.21%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSL-RTHYEKIILPYDIMLSADHDSNI--YISQSTVKP-----------------------KPVLHPSTTKKRKSLQSDPIDESLMETSN-ELKRLQFSGAGPRI-----------YASTKDEVKLEDDLVSGPLKRKCLSD-----YVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQ 2574
            M E   FV PPECPVF P+ EEF DPL +I +IRPIA K+GIC+I PP DW PPF+ +V  F+FTPRVQ+L ELEA +R+KLNF+ ++++F  LQGS +++ P++  + +DLY+L K+V   GG++ +   K W  +A +MG+       SL R+HYE+I+ PY++  S    + +     + T K                        K      T  K + L          E  N E K LQ  G  PR+           Y+  + ++K +   +    +++ L       Y C  CG GDKED+LL+CD   C D YH  CL PPL +VPK  W+C  CV E  SK    +GF  +   YTL  FG+ AD FK++YF   +H +VP   VEKEFWR++ S  +D+IVEYGADI S   GSGFP    +++GK  R  G+       +Y+N  WNLN +P+ ++SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SIN+LHWGEPKTWYGV +  AE+ E  M+K APELFD+  DLLH + T MNPN+LM+ GVPVYRT+Q AG+FVVTFPRAYH+GFNQG+NFAEAVNFC A+WL MGR CV HY +LHR+CVFSH+ELLC                             M++    LD  +   V+ E+  ++EEE + R  +++M +   EQ  FE + DDER C  C+TTCFLSA  C C                  R+VCL H  ++C+ CP+      YR+ LEE   +L G++ R Q + +W   +         + +A++ +K+  L +L++ L +  +  +     F + + +++  +  ++V +  L   Q
Sbjct:    1 MAEIVEFVPPPECPVFEPSWEEFSDPLGFINKIRPIAEKTGICKIRPPQDWQPPFACDVRNFRFTPRVQRLNELEAITRVKLNFLDQIAKFWELQGS-RIRFPHVERKILDLYQLSKIVSSEGGFEMVCKEKRWSTVAARMGFPPGRGTGSLLRSHYERILYPYELFQSGATLTGLQRLYDEGTEKEDVDEGVGEETTEEEQQDEEEEKEKEEQGEVTQNKEQILPERRSRRLKSERENKEPKSLQIFGTSPRMVGLEILSADDGYSKKQRQLKAQAFAIKMKPQKETLEVNFIDLYFCMVCGRGDKEDRLLLCDG--CDDSYHTFCLIPPLQEVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADHFKSDYFNMPVH-MVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDVGSGFP----VRDGK-RRLLGDEE-----EYANSGWNLNNMPVLEQSVLTHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINFLHWGEPKTWYGVPAAAAEKLEAVMKKVAPELFDSQPDLLHQLVTTMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPMGRQCVAHYRRLHRYCVFSHEELLC----------------------------KMAADPESLDVELAAAVYKEMSDMMEEESKLRQAMQEMGVLSSEQEFFELVPDDERQCHKCKTTCFLSALTCSC---------------SPTRLVCLHHAGDLCD-CPLGNACLRYRYDLEEFPSMLYGVKARAQSYDTWAKRVA-------EALSADQKNKK-DLIELKVLLEDAEDRKYPENASFRRLKEIVKEAETCSSVAQLLLSRKQ 808
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Match: kdm5ba (lysine-specific demethylase 5B [Source:NCBI gene;Acc:101160898])

HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0
Identity = 329/788 (41.75%), Postives = 463/788 (58.76%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIM----------LSADHDSNIYI-----SQSTVKPKPVLHPSTTKK-----RKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLED--------------DLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            F+ PPECPVF P+ EEF DP  YI +IRPIA K+GIC+I PP +W PPF+ +V+  +FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV+E GG+D +   + W KI+ KMG+       S LR HYE+I+ PY++           L+ D     Y       + +V+P+     +   K     R S +++P D       N  +R+    A P         VK E               + ++ P   K +  Y+C  CGSG  ED+LL+CD   C D YH  CL PPL +VPK  W+C  C+ +   K P+ +GF  +S +YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    ++N     +  + +      Y +  WNLN +P+   SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AE  E  M+K APELF++  DLLH + TIMNPN LM  G+P+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY QL R+CVFSHDE++C                            NM+     +D  +   VH ++++++++E++ R  + K+ +    Q  ++ L D+ER C  C+TTC+LS   C C ++               ++ CL H  ++C SCP S  T  Y+FTL+++  L+  +++R + +  W
Sbjct:    9 FIPPPECPVFEPSWEEFADPFAYINKIRPIAEKTGICKIRPPQEWQPPFACDVDRLKFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLYQLNKLVNEEGGFDAVCRERRWTKISVKMGFAPGKAIGSHLRAHYERILFPYNLFQTGANLPKATLTNDTKDKEYTPHDLPQRQSVQPQETCSIARRAKRMRSERGSFKTEPED-ICDNRPNLRRRMGTCAAKPEPVRMAVTVVKQEPTEHTDPTNYEESKINNINKPAGNK-VDQYICLVCGSGSAEDRLLLCDG--CDDSYHIFCLIPPLHEVPKGDWRCPKCLAQECGKPPVAFGFEQASRSYTLQTFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFP----VRNSHFEVSADDEH------YLSSGWNLNNMPVLDASVLTHITADICGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEHLESVMKKLAPELFESQPDLLHQLVTIMNPNTLMNNGIPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTMDWMPIGRSCVDHYRQLSRYCVFSHDEMVC----------------------------NMALKAKTMDVELASAVHEDMKVMIQDEKKLREWVSKLGVVLSRQVDYDELPDEERQCFKCRTTCYLSGVTCGCSSD---------------KMACLYHAQSLC-SCPFSNLTLNYKFTLDKLCPLMDSVKLRSESYKDW 736
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Match: kdm5ba (lysine-specific demethylase 5B [Source:NCBI gene;Acc:101160898])

HSP 1 Score: 632.484 bits (1630), Expect = 0.000e+0
Identity = 327/787 (41.55%), Postives = 466/787 (59.21%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIM---------LSADHDSNIYI-----SQSTVKPKPVLHPSTTKKR-------KSLQSDPIDESLMETSNELKRLQFSGA-----GPRIYASTKDEVKLEDDLV-----SGPLKRKCLS--DYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSW 2358
            F+ PPECPVF P+ EEF DP  YI +IRPIA K+GIC+I PP +W PPF+ +V+  +FTPR+Q+L ELEAQ+R+KLNF+ ++++F  LQG   LKIP++  + +DLY+L+KLV+E GG+D +   + W KI+ KMG+       S LR HYE+I+ PY++          L+ D     Y       + +V+P+     +   KR        S +++P  E + +    L+R   + A     G +     +  +    +++     S      C+S   Y+C  CGSG  ED+LL+CD   C D YH  CL PPL +VPK  W+C  C+ +   K P+ +GF  +S +YTL  FG  AD FK++YF   +H +VP   VEKEFWR++ +  +D+ VEYGADI S   GSGFP    ++N     +  + +      Y +  WNLN +P+   SVL  I  +I GMKVPW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AE  E  M+K APELF++  DLLH + TIMNPN LM  G+P+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY QL R+CVFSHDE++C                            NM+     +D  +   VH ++++++++E++ R  + K+ +    Q  ++ L D+ER C  C+TTC+LS   C C ++               ++ CL H  ++C SCP S  T  Y+FTL+++  L+  +++R + +  W
Sbjct:    9 FIPPPECPVFEPSWEEFADPFAYINKIRPIAEKTGICKIRPPQEWQPPFACDVDRLKFTPRIQRLNELEAQTRVKLNFLDQIAKFWELQGC-TLKIPHVERKILDLYQLNKLVNEEGGFDAVCRERRWTKISVKMGFAPGKAIGSHLRAHYERILFPYNLFQTGANLPATLTNDTKDKEYTPHDLPQRQSVQPQETCSIARRAKRMRSEVSRGSFKTEP--EDICDNRPNLRRRMGTCAAKPEPGKKTQVCRQRVIHFHGNMIWEASWSVLNVHPCVSVDQYICLVCGSGSAEDRLLLCDG--CDDSYHIFCLIPPLHEVPKGDWRCPKCLAQECGKPPVAFGFEQASRSYTLQTFGDMADSFKSDYFNMPVH-MVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFP----VRNSHFEVSADDEH------YLSSGWNLNNMPVLDASVLTHITADICGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGYAAEHLESVMKKLAPELFESQPDLLHQLVTIMNPNTLMNNGIPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTMDWMPIGRSCVDHYRQLSRYCVFSHDEMVC----------------------------NMALKAKTMDVELASAVHEDMKVMIQDEKKLREWVSKLGVVLSRQVDYDELPDEERQCFKCRTTCYLSGVTCGCSSD---------------KMACLYHAQSLC-SCPFSNLTLNYKFTLDKLCPLMDSVKLRSESYKDW 735
[Close]
BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Match: kdm5bb (lysine-specific demethylase 5B-B [Source:NCBI gene;Acc:101155110])

HSP 1 Score: 622.083 bits (1603), Expect = 0.000e+0
Identity = 333/799 (41.68%), Postives = 460/799 (57.57%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYS-LRTHYEKIILPYDIML----------------SADHDSNIYISQSTVKPKPVLHPSTTKKRKS--------LQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKR--KCLSDY---------------VCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F  PPECPVF P+ EEF+DP  +I +IRPIA K+GIC++ PP DW PPF+ +V+   F PR+Q+L ELEAQ+R+KLNF+ K+++F  LQG   LKIP++  + +DLYKL+KLV + GG++ +  ++ W KIA +MGY       S LR HYE+I+ PY +                  + D+  +    Q+   P P+     + +R          ++++P  E+     N  +R+    A P         VK E      P+    K  S Y               VC  C SG  ED+LL+CD   C D YH  CL PPL  VP+  W+C  C+ +  SK    +GF  +S  Y+L  FG+ AD FK++YF   +H +VP   VEKEFWR++ + ++D+ VEYGADI S   GSGFP    I NGK   +  +       +Y    WNLN L +   SVL  +  +I GM +PW YVGM FSSFCWHIEDHWS+SINYLHWGEPKTWYG     AEQ E  M+K APELF++  DLLH + TIMNPN LM  GVP+YRT+Q AG+FV+TFPRAYH+GFNQGFNFAEAVNFC  +W+ +GR CV+HY  LHR+ VFSHDE++C                            NM++    L+  +   VH ++  +++EER+ R K +KM +   ++  +++L+DDER C  C+TTC+LSA  C C    L               VCL HI ++C SCP++ +T  YR+TL+E+  ++S ++ R + +  W   +
Sbjct:   20 FKPPPECPVFEPSWEEFRDPYAFINKIRPIAEKTGICKVRPPPDWQPPFACDVDKLHFVPRIQRLNELEAQTRVKLNFLDKIAKFWDLQGCS-LKIPHVERKILDLYKLYKLVADEGGFEIVCQDRRWTKIALQMGYSPGKAIGSHLRGHYERILYPYTLFQNGANLLCVQKPVPQEETVDNKEHKLQEQAQRLPPPMTDTCPSARRAKRMKCEITCVKTEP-GEAGENKPNLRRRMGSFVAKPEPEKEIPISVKQEPLESKEPISEDDKSKSRYKKMIPLVTSNPVDLVVCLVCASGGDEDRLLLCDG--CDDSYHTYCLIPPLHDVPRGDWRCPKCLAQECSKPHEAFGFEQASRDYSLRAFGQMADAFKSDYFNMPVH-MVPTELVEKEFWRLVGAIDEDVTVEYGADIASKEFGSGFP----IPNGKFKVSPADE------KYLKCGWNLNNLAMMNPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPGFAAEQLESVMKKLAPELFESQPDLLHQLVTIMNPNTLMAYGVPIYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWMPLGRQCVDHYRMLHRYNVFSHDEMVC----------------------------NMAAKADTLNMVLASAVHKDMVFMIQEERELREKAKKMGVLDFKEAKYDHLQDDERQCAKCRTTCYLSAITCPCSPGVL---------------VCLYHIGDLC-SCPVTNYTLNYRYTLDELYPMMSAVKQRAELYDEWACRV 759
[Close]
BLAST of Lysine-specific demethylase vs. Planmine SMEST
Match: SMESG000063374.1 (SMESG000063374.1)

HSP 1 Score: 2944.84 bits (7633), Expect = 0.000e+0
Identity = 1443/1443 (100.00%), Postives = 1443/1443 (100.00%), Query Frame = 1 
Query:   82 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESDEVRLHVPKSVLIDCVRENGSVEIKNINVASLTEENLAHMNQTLIRFPLKLPCDQFEQMVARLLQWRQDSHTLMALNMNNPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGVFSLPVNLVKESTVFELVNHGETLISSVKETANELGDLGARFLLPISVSLQPALDGLYDVVAEINRLRDELSQLPKRGGISSQILASLKEATERCLCMGVRVSELDETRTRLYKACVDVILVTKPGRFVDMQHASQLVQLGSALFSEAVLDRESSPLTQKHLSSKTQITLMNRSIKKLKLSYVGCNTEHANNEICQLGCSDFDFLKILLPRFFSLDQNLNRDRLAHNNVQFLQIWHSCPVNENQIISLMRLYQTMIVEELSSIESMHSNKSSIAHSDLYCCVCEQSPIEKNSSYCMLCKPRSNRPTINEMAQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYSEIKNAKLTVPVCIKELFSQNTSTERKSIELSRIKDLFINLTYLRRVGYCLEVNVESYVAVXXXXXXXXXXXXXXXXAYHHDANIEADSSVTSVNI 4410
            MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAELELVVEEERQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESDEVRLHVPKSVLIDCVRENGSVEIKNINVASLTEENLAHMNQTLIRFPLKLPCDQFEQMVARLLQWRQDSHTLMALNMNNPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGVFSLPVNLVKESTVFELVNHGETLISSVKETANELGDLGARFLLPISVSLQPALDGLYDVVAEINRLRDELSQLPKRGGISSQILASLKEATERCLCMGVRVSELDETRTRLYKACVDVILVTKPGRFVDMQHASQLVQLGSALFSEAVLDRESSPLTQKHLSSKTQITLMNRSIKKLKLSYVGCNTEHANNEICQLGCSDFDFLKILLPRFFSLDQNLNRDRLAHNNVQFLQIWHSCPVNENQIISLMRLYQTMIVEELSSIESMHSNKSSIAHSDLYCCVCEQSPIEKNSSYCMLCKPRSNRPTINEMAQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYSEIKNAKLTVPVCIKELFSQNTSTERKSIELSRIKDLFINLTYLRRVGYCLEVNVESYVAVLSILIDCISNDINSSSAYHHDANIEADSSVTSVNI
Sbjct:    1 MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAELELVVEEERQFRMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLEVRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGFDSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESDEVRLHVPKSVLIDCVRENGSVEIKNINVASLTEENLAHMNQTLIRFPLKLPCDQFEQMVARLLQWRQDSHTLMALNMNNPGVLLPKVVHLFEEAKRLFPGWTAFTDERTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGVFSLPVNLVKESTVFELVNHGETLISSVKETANELGDLGARFLLPISVSLQPALDGLYDVVAEINRLRDELSQLPKRGGISSQILASLKEATERCLCMGVRVSELDETRTRLYKACVDVILVTKPGRFVDMQHASQLVQLGSALFSEAVLDRESSPLTQKHLSSKTQITLMNRSIKKLKLSYVGCNTEHANNEICQLGCSDFDFLKILLPRFFSLDQNLNRDRLAHNNVQFLQIWHSCPVNENQIISLMRLYQTMIVEELSSIESMHSNKSSIAHSDLYCCVCEQSPIEKNSSYCMLCKPRSNRPTINEMAQLNKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYSEIKNAKLTVPVCIKELFSQNTSTERKSIELSRIKDLFINLTYLRRVGYCLEVNVESYVAVLSILIDCISNDINSSSAYHHDANIEADSSVTSVNI 1443
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BLAST of Lysine-specific demethylase vs. Planmine SMEST
Match: SMESG000015058.1 (SMESG000015058.1)

HSP 1 Score: 531.561 bits (1368), Expect = 1.539e-159
Identity = 308/770 (40.00%), Postives = 433/770 (56.23%), Query Frame = 1 
Query:  100 FVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDDWTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGY--KSTSQAYSLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQSDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKCLSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCHNCVLEVLSKKPLE------YGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPCSSVEKEFWRILQSFN--DDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNNGEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLEQDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAXXXXXXXXXRQFRMKIEKM--NLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKMAEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFL-YRFTLEEMDRLLSGLEVRLQDFHSWEADI 2370
            F  PP  PVFRPT +EF+DPL+YIE+IRP+A K GIC+II P  W PPF+V+ +TF+F PRVQ+L E+ A SRIK NF+  +  F   Q ++ L+IP +    +DL++LH  V + GG   +  NK W  I  ++GY  KS      +R+++EKII PY      D   NI+I+++       + P T K + +L    ++   M  S  L                         +V  P+      + +CK C S      ++ C   +C+  YH  C+ PPLS VPK  W C  C L+V  +K L       +GF  S+  Y+L  F   AD FK  YF    +  V    VE+E+WR++ + N  DD++V+YGADI S    SGFPT          R N     +   +Y +  WNLN LP+ KKS+ RF+  +I GM VPWCYVGMVFS FCWHIEDHWS+SINYLH G+ KTWYGV   +AE+FE  MR++A ELF+   DLLHHITT +NP +L+K  + VYRTDQ AG+FVVTFPRAYHAGFNQGFNFAEAVNFCPA+WL+ GR  VE Y  + R  VFSH+EL+C +A +                                   + + V+ E+ ++ +EE+  R +I  M   + + E+ L + + +D+R C IC+TT ++S   C    ++ K+A+         R+ CL H++ +C SCP  E   L YR++L+E+  L+S +  +L+ +  W + +
Sbjct:    8 FERPPAAPVFRPTLKEFEDPLDYIEKIRPVAQKYGICKIISPKQWNPPFAVDSHTFKFRPRVQRLNEIGAHSRIKNNFIRTIEAFWECQ-NNPLEIPIVKNNPLDLFELHTKVKQYGGCHQVTKNKQWTHICRELGYGEKSKQLCSIVRSYFEKIIQPY-----LDFYDNIFINKNPDLFPENIQPKTMKYKTALT---LESPKMTRSKAL-------------------------IVQKPV------NELCKICESPTSPSTMVTCFECDCR--YHISCVDPPLSDVPKTGWICKRC-LQVSCQKELARLNTEVFGFSQSNCKYSLDSFSVYADNFKKTYFNDRKN--VSLKEVEEEYWRLVAAENVSDDVVVKYGADISSGLTSSGFPT----------RTNQTMFNEKDQKYVDSGWNLNNLPVLKKSIFRFVSNDISGMTVPWCYVGMVFSCFCWHIEDHWSYSINYLHTGDCKTWYGVPESDAEKFEDLMRQEASELFEKSPDLLHHITTQINPTLLIKNDIKVYRTDQAAGEFVVTFPRAYHAGFNQGFNFAEAVNFCPADWLTKGRASVESYRIVKRPSVFSHNELICKMASSLESLD----------------------------LLLLKAVYDEMMIIQQEEKLHRKQICTMVQGVCRTERLLLDQIPEDDRECMICRTTLYISGVTCSVCCQD-KLAD---------RMSCLDHVSQLC-SCPSKENIVLKYRYSLDEITVLVSNVHKQLEQYKLWMSRV 683
[Close]
BLAST of Lysine-specific demethylase vs. Planmine SMEST
Match: SMESG000036910.1 (SMESG000036910.1)

HSP 1 Score: 129.413 bits (324), Expect = 5.838e-30
Identity = 60/158 (37.97%), Postives = 89/158 (56.33%), Query Frame = 1 
Query: 1315 SNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGR 1788
            S ++WN+  LP    SVL   +  +DG+  P+ Y G   ++F WH+ED   +SINYLH G PK WY +    A++FE+  R      F      L H T +++P+ L ++G+P  +  Q+  +F+ TFP  YHAGFN G N AE+ NF    W+  G+
Sbjct:  156 SQKVWNIAHLPTLLSSVLEEQKLKLDGVNTPYLYFGSWQTTFGWHVEDVDLYSINYLHHGMPKHWYVIPPAYAKKFEMIARDLYKADFLKCNLFLRHKTVVLSPHFLRRQGIPTRKIVQEENEFMYTFPYGYHAGFNMGLNIAESTNFAGPRWIEFGK 313
[Close]
BLAST of Lysine-specific demethylase vs. Planmine SMEST
Match: SMESG000042544.1 (SMESG000042544.1)

HSP 1 Score: 116.701 bits (291), Expect = 4.439e-27
Identity = 57/158 (36.08%), Postives = 85/158 (53.80%), Query Frame = 1 
Query: 1315 SNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVFSSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFDNHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQGFNFAEAVNFCPANWLSMGR 1788
            S E WN+  LP     VL+     I G+  P+ Y G   S+F WH+ED   +SINYLH+G  K WY +    + +FE  ++K     ++     L H   I++P  L   G+P  +  Q+  +F++TFP  YH+GFN G N AE+ NF  + W+  G+
Sbjct:  156 SQEYWNIAALPSILSDVLK---EPIGGVNTPYLYFGSWRSTFGWHVEDVDLYSINYLHFGMAKFWYVIPPPFSRRFENLVKKLFSVEYEKCPAFLRHKVVIISPEFLRLNGIPTRKILQEENEFMITFPYGYHSGFNTGLNIAESTNFASSRWIEYGK 310
[Close]
BLAST of Lysine-specific demethylase vs. Planmine SMEST
Match: SMESG000013107.1 (SMESG000013107.1)

HSP 1 Score: 62.003 bits (149), Expect = 3.113e-9
Identity = 38/109 (34.86%), Postives = 61/109 (55.96%), Query Frame = 1 
Query:  253 NVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKLKIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKS--TSQAYSLRTHYEKIILPYD 573
            NV  + +  + ++LYEL    + K  F+  L  F++ +GS   +IP +  + +DLY L+KLV   GG   +I  KLW +I   +   S  TS A++LRT Y K + P++
Sbjct:  221 NVQNWNYEEQFKQLYELSDDCKRK-EFLDDLFSFMQKKGSPVNRIPIMAKQVLDLYTLYKLVVSRGGLVEVINKKLWREITKGLNLPSSITSAAFTLRTQYMKYLYPFE 328
The following BLAST results are available for this feature:
BLAST of Lysine-specific demethylase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
KDM5A0.000e+042.77lysine demethylase 5A [Source:HGNC Symbol;Acc:HGNC... [more]
KDM5C0.000e+042.71lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC... [more]
KDM5C0.000e+042.33lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC... [more]
KDM5C0.000e+042.33lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC... [more]
KDM5D0.000e+043.59lysine demethylase 5D [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rbr-22.254e-14635.18Lysine-specific demethylase rbr-2 [Source:UniProt... [more]
rbr-23.958e-14635.20Lysine-specific demethylase rbr-2 [Source:UniProt... [more]
jmjd-21.993e-2837.65Lysine-specific demethylase 4 [Source:UniProtKB/S... [more]
set-161.115e-741.43Histone-lysine N-methyltransferase [Source:UniPro... [more]
cfi-13.828e-732.14AT-rich interactive domain-containing protein cfi-... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lid0.000e+042.44gene:FBgn0031759 transcript:FBtr0079231[more]
lid0.000e+042.44gene:FBgn0031759 transcript:FBtr0079232[more]
lid0.000e+042.44gene:FBgn0031759 transcript:FBtr0307070[more]
lid0.000e+042.44gene:FBgn0031759 transcript:FBtr0345336[more]
lid0.000e+042.44gene:FBgn0031759 transcript:FBtr0307071[more]
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BLAST of Lysine-specific demethylase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdm5bb0.000e+041.88lysine (K)-specific demethylase 5Bb [Source:NCBI g... [more]
kdm5ba0.000e+042.00lysine (K)-specific demethylase 5Ba [Source:ZFIN;A... [more]
kdm5ba0.000e+041.94lysine (K)-specific demethylase 5Ba [Source:ZFIN;A... [more]
kdm5ba0.000e+042.23lysine (K)-specific demethylase 5Ba [Source:ZFIN;A... [more]
kdm5bb3.888e-17740.69lysine (K)-specific demethylase 5Bb [Source:NCBI g... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
elp10.000e+044.74elongator complex protein 1 [Source:Xenbase;Acc:XB... [more]
elp10.000e+044.74elongator complex protein 1 [Source:Xenbase;Acc:XB... [more]
elp10.000e+044.74elongator complex protein 1 [Source:Xenbase;Acc:XB... [more]
lamp20.000e+042.37lysosomal-associated membrane protein 2 [Source:Xe... [more]
lamp20.000e+043.36lysosomal-associated membrane protein 2 [Source:Xe... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Kdm5c0.000e+042.12lysine (K)-specific demethylase 5C [Source:MGI Sym... [more]
Kdm5c0.000e+042.12lysine (K)-specific demethylase 5C [Source:MGI Sym... [more]
Kdm5a0.000e+041.47lysine (K)-specific demethylase 5A [Source:MGI Sym... [more]
Kdm5d0.000e+043.31lysine (K)-specific demethylase 5D [Source:MGI Sym... [more]
Kdm5a0.000e+042.30lysine (K)-specific demethylase 5A [Source:MGI Sym... [more]
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BLAST of Lysine-specific demethylase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q30DN6|KDM5D_CANLF0.000e+044.04Lysine-specific demethylase 5D OS=Canis lupus fami... [more]
sp|Q38JA7|KDM5C_CANLF0.000e+042.00Lysine-specific demethylase 5C OS=Canis lupus fami... [more]
sp|P41230|KDM5C_MOUSE0.000e+042.12Lysine-specific demethylase 5C OS=Mus musculus OX=... [more]
sp|P29375|KDM5A_HUMAN0.000e+042.77Lysine-specific demethylase 5A OS=Homo sapiens OX=... [more]
sp|P41229|KDM5C_HUMAN0.000e+042.33Lysine-specific demethylase 5C OS=Homo sapiens OX=... [more]
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BLAST of Lysine-specific demethylase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A481NV480.000e+087.11Lysine-specific demethylase OS=Dugesia japonica OX... [more]
A0A4Z2D5L60.000e+042.98Lysine-specific demethylase 5D OS=Schistosoma japo... [more]
A0A504Y4G60.000e+042.64Lysine-specific demethylase 5D OS=Fasciola giganti... [more]
A0A4E0RUD10.000e+042.87Lysine-specific demethylase 5D OS=Fasciola hepatic... [more]
A0A183JBT50.000e+044.93Uncharacterized protein OS=Schistosoma curassoni O... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdm5c0.000e+042.51lysine demethylase 5C [Source:NCBI gene;Acc:103035... [more]
kdm5a0.000e+042.76lysine (K)-specific demethylase 5A [Source:ZFIN;Ac... [more]
kdm5bb0.000e+042.82lysine-specific demethylase 5B-B-like [Source:NCBI... [more]
kdm5bb0.000e+041.32lysine-specific demethylase 5B-B-like [Source:NCBI... [more]
kdm5ba0.000e+041.58lysine (K)-specific demethylase 5Ba [Source:ZFIN;A... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdm5c0.000e+043.90lysine (K)-specific demethylase 5C [Source:ZFIN;Ac... [more]
kdm5c0.000e+038.58lysine (K)-specific demethylase 5C [Source:ZFIN;Ac... [more]
jarid2a5.202e-3425.98jumonji, AT rich interactive domain 2a [Source:ZFI... [more]
ENSPMAT00000010019.11.823e-1331.06pep scaffold:Pmarinus_7.0:GL481681:6200:13508:-1 g... [more]
ENSPMAT00000005177.14.652e-1241.33pep scaffold:Pmarinus_7.0:GL477523:31773:39538:1 g... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4
Match NameE-valueIdentityDescription
JHD23.149e-7829.76JmjC domain family histone demethylase; promotes g... [more]
RPH18.665e-2936.13JmjC domain-containing histone demethylase; target... [more]
GIS13.997e-1933.56Histone demethylase and transcription factor; regu... [more]
ECM54.612e-1831.64Subunit of the Snt2C complex; physically associate... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO348831.435e-8341.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO464791.944e-3132.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO455845.661e-1032.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO390571.252e-935.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO492417.036e-930.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Lysine-specific demethylase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kdm5c0.000e+041.26lysine demethylase 5C [Source:NCBI gene;Acc:101167... [more]
kdm5a0.000e+041.19lysine demethylase 5A [Source:NCBI gene;Acc:101161... [more]
kdm5ba0.000e+041.75lysine-specific demethylase 5B [Source:NCBI gene;A... [more]
kdm5ba0.000e+041.55lysine-specific demethylase 5B [Source:NCBI gene;A... [more]
kdm5bb0.000e+041.68lysine-specific demethylase 5B-B [Source:NCBI gene... [more]
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BLAST of Lysine-specific demethylase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000063374.10.000e+0100.00SMESG000063374.1[more]
SMESG000015058.11.539e-15940.00SMESG000015058.1[more]
SMESG000036910.15.838e-3037.97SMESG000036910.1[more]
SMESG000042544.14.439e-2736.08SMESG000042544.1[more]
SMESG000013107.13.113e-934.86SMESG000013107.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001441 ID=SMED30001441|Name=Lysine-specific demethylase|organism=Schmidtea mediterranea sexual|type=transcript|length=4454bp
CGTAGTAATTTGTTTTAATTTTTTTGATAAACACAAAATTTGCTTTTACA
GATTTTTTAATTAAGCAAATATATCCACGAAATGGAAGAGCATTTTACTT
TCGTTTCACCTCCTGAGTGTCCTGTGTTTAGACCCACTAAAGAAGAATTC
AAAGATCCTCTTGAATACATTGAGCAAATTAGACCGATTGCTGTCAAATC
CGGAATCTGTAGAATAATTCCTCCTGATGATTGGACTCCTCCATTTTCTG
TAAATGTTAATACATTTCAATTTACTCCACGAGTCCAAAAACTCTATGAG
CTAGAAGCCCAGTCTAGAATAAAATTGAATTTTATGACTAAATTATCACA
ATTTGTGAGATTACAGGGGTCTGATAAATTAAAAATTCCGAACATTAATG
GTAGACACGTTGATTTGTACAAATTGCATAAACTTGTTCATGAAAATGGG
GGCTATGATCATATAATTGCAAATAAATTGTGGCTAAAAATAGCAACAAA
AATGGGTTATAAGAGTACAAGTCAAGCTTACTCTTTGCGTACTCACTATG
AAAAAATAATTCTTCCTTATGATATAATGCTGTCTGCTGATCATGATTCA
AATATTTATATTTCTCAATCCACGGTTAAACCAAAGCCTGTTCTTCATCC
TTCGACTACAAAAAAACGAAAATCTTTGCAGTCTGATCCAATTGATGAAT
CACTAATGGAAACCAGCAATGAATTGAAAAGACTTCAGTTTTCTGGAGCC
GGGCCAAGAATTTATGCGAGCACGAAAGATGAAGTTAAACTCGAAGACGA
TTTAGTTTCTGGACCGTTAAAACGAAAATGTTTATCGGATTATGTGTGTA
AGACTTGTGGAAGTGGAGATAAAGAAGATAAATTATTAATCTGTGACAAC
GAGGAATGTCAAGATTGTTACCATTGTGACTGTTTAGCTCCGCCATTATC
TCAAGTTCCTAAACAAAGTTGGAAATGCCATAATTGTGTTCTTGAAGTTC
TTAGCAAGAAACCGCTTGAATATGGATTTCCAAGTTCGAGTATTACATAT
ACACTTTATGAATTTGGCAAATCGGCCGACAAATTCAAAGCTAATTATTT
TGGTAAAGAATTACATGAATTGGTGCCATGTAGTTCAGTTGAAAAGGAGT
TTTGGCGAATATTGCAATCTTTTAATGACGATATAATTGTCGAGTATGGT
GCTGATATCCATTCAAGTCATCAAGGGTCAGGCTTCCCGACATTGGAAAA
CATTAAAAACGGAAAATGTGCTCGAAATAATGGCGAACCAAATATGGATT
TAGCTATCCAATATTCGAATGAATTATGGAATTTGAATATTTTACCCATT
ACAAAAAAATCAGTACTACGTTTTATTCGAGGAAATATAGATGGTATGAA
AGTGCCTTGGTGTTATGTCGGAATGGTTTTTTCAAGTTTTTGTTGGCACA
TTGAAGATCATTGGAGTTTTTCTATAAATTATCTACATTGGGGGGAACCT
AAAACTTGGTATGGTGTGTCTAGTGAAAACGCAGAACAATTTGAAGTTGC
GATGCGCAAACAAGCTCCTGAATTGTTTGACAACCATGAAGACTTATTAC
ATCACATAACGACAATAATGAATCCGAATATCTTAATGAAAGAAGGAGTT
CCAGTTTATAGAACAGATCAGCAAGCAGGTCAATTTGTTGTGACGTTTCC
CAGAGCCTACCATGCAGGGTTTAACCAAGGGTTTAATTTCGCGGAAGCGG
TAAATTTTTGCCCTGCCAACTGGTTGTCAATGGGCAGGTTATGTGTCGAA
CATTACGCTCAACTTCATCGTCACTGTGTATTTTCTCACGATGAACTGTT
ATGCACAATCGCAGAAGCGGCTTTATTGGAACAGGATAATATCCCGGATG
AAGAAATTCCAGTTAAATATCCGTTGATGTCAGGATTGAACATGTCATCT
ACCGATATTTGTCTTGACACAAATATACGTCGAACTGTTCATGCTGAATT
AGAACTTGTAGTCGAAGAAGAACGACAATTTCGAATGAAAATAGAAAAAA
TGAACTTGACCAAAATCGAACAAACTCTGTTTGAGAATTTAAAAGATGAT
GAGCGAGCTTGTTGCATTTGTCAAACGACTTGTTTTCTATCCGCTTTCCG
ATGTCAGTGTATCAATGAAGAATTGAAAATGGCTGAAGATATGAAAACGG
AAAAGAAATTGAAGAGAATTGTTTGCTTGCGCCATATAAATAATGTTTGT
AATTCATGTCCGATCAGTGAGTGGACATTTTTATATCGGTTTACTTTGGA
GGAAATGGATAGATTGCTTTCTGGTTTGGAAGTTCGGCTTCAAGATTTTC
ATTCATGGGAGGCTGATATTAAAGCTCATTGCACAGAAGGGCCAGCATCG
TTCACTGCCAATGAGCCTGATAAACGTTGGAGTTTGGATCAACTTCAAAT
GAGATTGAATGAAGGAGCTGAATGTGGCTTTGATAGTTGTGAAGAATTCG
TAAAATCTAGAGGATTATTGGAACGAGGTCAAAATCTTACAAATGTTTGC
AAACACTGGTTGAAAGCCATTCAGAACAGCGATGATTGCTCAAAGTTAGA
TGAATCGGACGAAGTTAGGCTTCATGTCCCTAAATCGGTTCTAATCGATT
GTGTTCGTGAAAATGGATCTGTTGAAATCAAGAATATCAATGTTGCCAGT
TTAACTGAAGAAAATCTGGCTCATATGAATCAAACTCTTATACGATTTCC
TTTAAAATTACCATGTGATCAATTTGAACAGATGGTTGCACGGCTACTTC
AATGGCGTCAAGATAGCCACACATTAATGGCATTGAATATGAACAATCCC
GGTGTGTTGTTGCCAAAAGTTGTGCATTTGTTTGAAGAAGCTAAACGATT
ATTTCCCGGTTGGACCGCATTTACCGATGAAAGAACTTGTTTAATGCTTT
TGGGGAAAAGTTTACAGTGGTTAGTAAGGATTAGAGAATGTGAGGATGCT
GTCAAAGCTGGAAAATCTGCACATCTCGGTCAAAGTGAAGGCGTTTTTTC
TCTGCCAGTTAATTTGGTGAAAGAAAGCACCGTGTTTGAGTTGGTAAATC
ACGGAGAGACACTTATTTCATCTGTCAAAGAAACAGCCAATGAACTTGGC
GATTTGGGTGCTCGGTTTCTATTGCCAATTTCTGTTTCACTTCAACCGGC
GCTTGATGGTTTGTACGATGTCGTTGCAGAAATTAATCGATTACGCGATG
AATTATCCCAATTGCCAAAACGAGGTGGTATCTCATCGCAAATACTAGCC
TCATTGAAGGAAGCAACCGAACGCTGCCTGTGTATGGGAGTTCGAGTCAG
TGAATTAGATGAAACAAGAACTCGTCTTTATAAGGCATGTGTAGATGTTA
TTCTTGTCACAAAACCTGGGAGATTTGTCGATATGCAACACGCTTCTCAA
TTGGTCCAACTCGGAAGTGCTTTGTTCAGTGAGGCCGTACTAGACCGAGA
AAGTAGTCCACTTACTCAAAAGCATTTATCTAGTAAAACACAAATTACAC
TAATGAATCGATCCATCAAAAAACTCAAGTTATCGTATGTCGGTTGTAAT
ACAGAACATGCAAACAACGAAATTTGCCAATTGGGATGCAGTGATTTTGA
TTTCTTGAAGATTTTACTCCCGAGATTTTTCTCACTTGACCAAAACCTGA
ATCGCGATCGTCTGGCTCATAACAATGTACAGTTTCTTCAAATCTGGCAT
TCCTGTCCTGTCAACGAAAATCAGATTATATCTCTTATGCGTCTGTATCA
AACGATGATTGTTGAAGAATTGTCAAGTATTGAATCGATGCATTCAAATA
AATCCTCGATAGCACATTCCGATTTGTACTGTTGTGTATGTGAACAGTCT
CCAATTGAGAAAAATTCTTCATATTGCATGTTATGTAAGCCCCGAAGTAA
TCGTCCAACTATCAATGAAATGGCCCAATTAAACAAACTTCTGAAGCAAT
GTCCGAATATCGTATCCGTGTACGGAATAGCACTCCAGGCTTTAAGCAAG
CGTACTGTTACTTGGCTGGAGTCTTTGGTCGCATTGATTCGATTACATGC
AAAATATCTTTCTAGATTTTATTCAGAAATTAAGAATGCTAAATTAACTG
TTCCTGTTTGTATAAAAGAGTTATTTTCTCAAAACACTTCTACAGAACGA
AAATCAATTGAATTATCCCGGATAAAAGACTTGTTCATTAATTTAACATA
CCTTCGCCGAGTAGGATATTGCCTAGAAGTTAATGTTGAATCTTATGTGG
CAGTCCTGTCCATTCTAATTGATTGTATTAGTAATGACATCAATTCATCT
TCAGCCTATCATCACGACGCAAATATAGAAGCAGATTCGAGTGTTACTTC
TGTTAATATATAAATTTTCATGTGTTTTGTAGATAATAAATTGTATTTAG
AGAT
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protein sequence of SMED30001441-orf-1

>SMED30001441-orf-1 ID=SMED30001441-orf-1|Name=SMED30001441-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1444bp
MEEHFTFVSPPECPVFRPTKEEFKDPLEYIEQIRPIAVKSGICRIIPPDD
WTPPFSVNVNTFQFTPRVQKLYELEAQSRIKLNFMTKLSQFVRLQGSDKL
KIPNINGRHVDLYKLHKLVHENGGYDHIIANKLWLKIATKMGYKSTSQAY
SLRTHYEKIILPYDIMLSADHDSNIYISQSTVKPKPVLHPSTTKKRKSLQ
SDPIDESLMETSNELKRLQFSGAGPRIYASTKDEVKLEDDLVSGPLKRKC
LSDYVCKTCGSGDKEDKLLICDNEECQDCYHCDCLAPPLSQVPKQSWKCH
NCVLEVLSKKPLEYGFPSSSITYTLYEFGKSADKFKANYFGKELHELVPC
SSVEKEFWRILQSFNDDIIVEYGADIHSSHQGSGFPTLENIKNGKCARNN
GEPNMDLAIQYSNELWNLNILPITKKSVLRFIRGNIDGMKVPWCYVGMVF
SSFCWHIEDHWSFSINYLHWGEPKTWYGVSSENAEQFEVAMRKQAPELFD
NHEDLLHHITTIMNPNILMKEGVPVYRTDQQAGQFVVTFPRAYHAGFNQG
FNFAEAVNFCPANWLSMGRLCVEHYAQLHRHCVFSHDELLCTIAEAALLE
QDNIPDEEIPVKYPLMSGLNMSSTDICLDTNIRRTVHAELELVVEEERQF
RMKIEKMNLTKIEQTLFENLKDDERACCICQTTCFLSAFRCQCINEELKM
AEDMKTEKKLKRIVCLRHINNVCNSCPISEWTFLYRFTLEEMDRLLSGLE
VRLQDFHSWEADIKAHCTEGPASFTANEPDKRWSLDQLQMRLNEGAECGF
DSCEEFVKSRGLLERGQNLTNVCKHWLKAIQNSDDCSKLDESDEVRLHVP
KSVLIDCVRENGSVEIKNINVASLTEENLAHMNQTLIRFPLKLPCDQFEQ
MVARLLQWRQDSHTLMALNMNNPGVLLPKVVHLFEEAKRLFPGWTAFTDE
RTCLMLLGKSLQWLVRIRECEDAVKAGKSAHLGQSEGVFSLPVNLVKEST
VFELVNHGETLISSVKETANELGDLGARFLLPISVSLQPALDGLYDVVAE
INRLRDELSQLPKRGGISSQILASLKEATERCLCMGVRVSELDETRTRLY
KACVDVILVTKPGRFVDMQHASQLVQLGSALFSEAVLDRESSPLTQKHLS
SKTQITLMNRSIKKLKLSYVGCNTEHANNEICQLGCSDFDFLKILLPRFF
SLDQNLNRDRLAHNNVQFLQIWHSCPVNENQIISLMRLYQTMIVEELSSI
ESMHSNKSSIAHSDLYCCVCEQSPIEKNSSYCMLCKPRSNRPTINEMAQL
NKLLKQCPNIVSVYGIALQALSKRTVTWLESLVALIRLHAKYLSRFYSEI
KNAKLTVPVCIKELFSQNTSTERKSIELSRIKDLFINLTYLRRVGYCLEV
NVESYVAVLSILIDCISNDINSSSAYHHDANIEADSSVTSVNI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR036431ARID_dom_sf
IPR003349JmjN
IPR001965Znf_PHD
IPR001606ARID_dom
IPR003347JmjC_dom
IPR004198Znf_C5HC2
IPR013083Znf_RING/FYVE/PHD
IPR019786Zinc_finger_PHD-type_CS
IPR019787Znf_PHD-finger
IPR011011Znf_FYVE_PHD
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0003677DNA binding
GO:0008168methyltransferase activity
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0032259methylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableSMARTSM01014ARID_2coord: 75..164
e-value: 9.8E-30
score: 114.8
NoneNo IPR availableGENE3DG3DSA:2.60.120.650coord: 285..582
e-value: 1.6E-112
score: 378.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 186..206
NoneNo IPR availablePANTHERPTHR10694JUMONJI DOMAIN CONTAINING PROTEINcoord: 6..594
coord: 621..761
NoneNo IPR availablePANTHERPTHR10694:SF17LYSINE-SPECIFIC DEMETHYLASE 5Acoord: 6..594
coord: 621..761
NoneNo IPR availableCDDcd16864ARID_JARIDcoord: 78..164
e-value: 2.65331E-29
score: 110.478
NoneNo IPR availableSUPERFAMILYSSF51197Clavaminate synthase-likecoord: 372..596
IPR003349JmjN domainSMARTSM00545JmjN_1coord: 12..53
e-value: 5.4E-23
score: 92.4
IPR003349JmjN domainPFAMPF02375JmjNcoord: 14..47
e-value: 6.6E-16
score: 58.0
IPR003349JmjN domainPROSITEPS51183JMJNcoord: 13..54
score: 18.996
IPR003347JmjC domainSMARTSM00558cupin_9coord: 410..576
e-value: 7.0E-63
score: 224.9
IPR003347JmjC domainPFAMPF02373JmjCcoord: 443..559
e-value: 1.1E-42
score: 145.1
IPR003347JmjC domainPROSITEPS51184JMJCcoord: 410..576
score: 37.914
IPR001965Zinc finger, PHD-typeSMARTSM00249PHD_3coord: 255..303
e-value: 1.5E-6
score: 37.8
IPR001606ARID DNA-binding domainSMARTSM00501bright_3coord: 79..169
e-value: 1.3E-26
score: 104.4
IPR001606ARID DNA-binding domainPFAMPF01388ARIDcoord: 81..164
e-value: 2.0E-20
score: 73.3
IPR001606ARID DNA-binding domainPROSITEPS51011ARIDcoord: 78..168
score: 27.102
IPR004198Zinc finger, C5HC2-typePFAMPF02928zf-C5HC2coord: 677..744
e-value: 1.3E-11
score: 44.7
IPR036431ARID DNA-binding domain superfamilyGENE3DG3DSA:1.10.150.60coord: 66..170
e-value: 8.3E-33
score: 114.5
IPR036431ARID DNA-binding domain superfamilySUPERFAMILYSSF46774ARID-likecoord: 58..169
IPR019786Zinc finger, PHD-type, conserved sitePROSITEPS01359ZF_PHD_1coord: 256..302
IPR019787Zinc finger, PHD-fingerPROSITEPS50016ZF_PHD_2coord: 253..305
score: 9.632
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILYSSF57903FYVE/PHD zinc fingercoord: 248..308