SMED30001431

Overview


Name	SMED30001431
Smed ID	SMED30001431
Length (bp)	1367

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SMED30001431 (SMED30001431) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30001431 (SMED30001431) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001431

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
epidermis	SMED30001431	h1SMcG0000458	dd_Smed_v4_84774_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of SMED30001431 vs. Ensembl Human
Match: HTRA1 (HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476])

HSP 1 Score: 63.929 bits (154), Expect = 2.022e-19
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N   Y+A+I   D+  D+ALIKI+    KL  L      +L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  104 SEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQG-KLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 216

HSP 2 Score: 52.373 bits (124), Expect = 2.022e-19
Identity = 40/153 (26.14%), Postives = 67/153 (43.79%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  +  AK +   +    G +M         S   KE +  +  +  V      +  YI  V P + A   GL + DV+ S++G  + S +D      R   +N+ + R  E + +
Sbjct:  223 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMS-----LTSSKAKELKDRHRDFPDVI-----SGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMI 365

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BLAST of SMED30001431 vs. Ensembl Human
Match: HTRA1 (HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476])

HSP 1 Score: 62.3882 bits (150), Expect = 1.589e-18
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N   Y+A+I   D+  D+ALIKI+    KL  L      +L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  210 SEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKID-HQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 322

HSP 2 Score: 50.447 bits (119), Expect = 1.589e-18
Identity = 40/153 (26.14%), Postives = 67/153 (43.79%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  +  AK +   +    G +M         S   KE +  +  +  V      +  YI  V P + A   GL + DV+ S++G  + S +D      R   +N+ + R  E + +
Sbjct:  329 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMS-----LTSSKAKELKDRHRDFPDVI-----SGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMI 471

[Close]

BLAST of SMED30001431 vs. Ensembl Human
Match: HTRA4 (HtrA serine peptidase 4 [Source:HGNC Symbol;Acc:HGNC:26909])

HSP 1 Score: 56.6102 bits (135), Expect = 4.966e-18
Identity = 48/153 (31.37%), Postives = 72/153 (47.06%), Query Frame = -2

Query:  722 NIVSKTVESVTSSLVHXXXXXXXXXXXXXV----------NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVIS-----DVELDKKSHSIKYIYSDA 1135
            N ++  VE V  S+VHV + G  +    +V          +E+G I+TN H + N+  + V L N   Y+A +   D  LDLA+IKI   N +L  L       L  GE+V+A+ S     N+   G++S       EL  K   + Y+  DA
Sbjct:  168 NFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIE-SNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDA 319

HSP 2 Score: 54.6842 bits (130), Expect = 4.966e-18
Identity = 40/153 (26.14%), Postives = 78/153 (50.98%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  G++IG NS+R       A  S   ++F+ E   +  K +        G QM          P+++E ++ Y  +  V+     + VY+  V   ++A  +GL D DV+ +++G  I +T+D ++ A   + ++++++R  ++L L
Sbjct:  327 GGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLS-----LTVPLSEELKMHYPDFPDVS-----SGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVK-ALDSDSLSMAVLRGKDNLLL 468

[Close]

BLAST of SMED30001431 vs. Ensembl Human
Match: HTRA3 (HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406])

HSP 1 Score: 57.3806 bits (137), Expect = 4.903e-15
Identity = 42/120 (35.00%), Postives = 60/120 (50.00%), Query Frame = -2

Query:  719 NENGYILTNVHEI------FNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E G I+TN H +        +  L V+L N ++Y+A I   DK  D+A IKI+P   KL  L       L  GE+V+AI S     N+V  G++S       EL  +   + YI +DAI
Sbjct:  181 SEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHP-KKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAI 299

HSP 2 Score: 43.8986 bits (102), Expect = 4.903e-15
Identity = 35/148 (23.65%), Postives = 65/148 (43.92%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE+IG N+++       A  S    +F+ E   +   K+  K+             G+ +  +T     +     P   E   + +Y+  V+P S + + G+ D D++  V+G  +  +S+ +Q A   E   +  +R G
Sbjct:  306 GGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTE-FQDKQIKDWKKRF-----------IGIRMRTITPSLVDELKASNPDFPE-VSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSE-LQEAVLTESPLLLEVRRG 439

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BLAST of SMED30001431 vs. Ensembl Human
Match: HTRA2 (HtrA serine peptidase 2 [Source:HGNC Symbol;Acc:HGNC:14348])

HSP 1 Score: 46.595 bits (109), Expect = 1.400e-11
Identity = 30/111 (27.03%), Postives = 57/111 (51.35%), Query Frame = -2

Query:  722 NGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVE-----LDKKSHSIKYIYSDA 1039
            +G I+TN H + ++  + VRL + + Y+A + A D + D+A ++I      L  L       +  GE+V+A+ S     N++  G++S  +     L     +++YI +DA
Sbjct:  190 DGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQ-TKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDA 299

HSP 2 Score: 43.1282 bits (100), Expect = 1.400e-11
Identity = 40/155 (25.81%), Postives = 69/155 (44.52%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQE-EINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   ++F+   E  N +      Q    G  M      + +SP +  E QL    +  V      + V I+ V   S A++AGL   DV+ ++   ++ +  D  +    + ++ + I R  E+L L
Sbjct:  307 GGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMM------LTLSPSILAELQLREPSFPDV-----QHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRETLTL 450

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BLAST of SMED30001431 vs. Ensembl Fly
Match: HtrA2 (gene:FBgn0038233 transcript:FBtr0082987)

HSP 1 Score: 65.0846 bits (157), Expect = 4.307e-11
Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = -2

Query:  722 ENGYILTNVHEIFNKP--CLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDA 1042
            +NG ILTN H + NKP   + VRL +   + A I   D+  DLA ++I   N  LS +       L  GE+V+A+ S     N+V  GVIS       EL  ++  I Y+ +DA
Sbjct:  148 QNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNN--LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDA 259

[Close]

BLAST of SMED30001431 vs. Ensembl Fly
Match: HtrA2 (gene:FBgn0038233 transcript:FBtr0330045)

HSP 1 Score: 65.0846 bits (157), Expect = 4.307e-11
Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = -2

Query:  722 ENGYILTNVHEIFNKP--CLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDA 1042
            +NG ILTN H + NKP   + VRL +   + A I   D+  DLA ++I   N  LS +       L  GE+V+A+ S     N+V  GVIS       EL  ++  I Y+ +DA
Sbjct:  148 QNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNN--LSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDA 259

[Close]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Match: htra4 (HtrA serine peptidase 4 [Source:ZFIN;Acc:ZDB-GENE-131120-192])

HSP 1 Score: 63.1586 bits (152), Expect = 4.779e-21
Identity = 42/114 (36.84%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G+I+TN H + NK  + V L N   Y A I   D+ LD+ALIKI+     L  L       L  GE+V+A+ S     N+V  G+IS       EL  ++  ++YI +DAI
Sbjct:  190 SEDGWIVTNAHVLSNKQRIKVELKNGMLYDATIKDVDQKLDIALIKID-SETALPVLLLGRSSDLRPGEFVVAVGSPFSLQNTVTTGIISTTHRGGHELGLQNSDMEYIQTDAI 302

HSP 2 Score: 57.7658 bits (138), Expect = 4.779e-21
Identity = 39/153 (25.49%), Postives = 71/153 (46.41%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  G++IG N+++       A  S   ++F+ +      K     +    G +M +    +      KE        +P       + VY+Y V P ++A+ AG+L+ DV+ S++G  +YST D  Q     E +++ + R  + + L
Sbjct:  309 GGPLVNLDGDVIGINTLKVTPGISFAIPSDRIRQFLADSYERQRKGRTLTKKKYMGVRMLQLSAALIRELREKESS------FP----DVSSGVYVYEVIPGTAAFSAGMLNQDVIISINGQPVYSTEDVSQAVQSNEILSLMVRRAQKEITL 451

[Close]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Match: htra1a (HtrA serine peptidase 1a [Source:NCBI gene;Acc:431766])

HSP 1 Score: 62.003 bits (149), Expect = 4.699e-17
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +++G I+TN H + NK  + V L N  +Y A+I   D+  D+ALIKI+  N KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  209 SDDGLIVTNAHVVANKNRVKVELKNGASYDAKIKDVDEKADIALIKIDLPN-KLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 321

HSP 2 Score: 45.4394 bits (106), Expect = 4.699e-17
Identity = 41/170 (24.12%), Postives = 75/170 (44.12%), Query Frame = -1

Query:  138 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMD 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E  +  A+     +    G +M      + ++P ++KE +   L  +P       +  Y+  V  K+ A   GL + DV+ S++G  I + +D      +   + + + R  E + L           IIPM+
Sbjct:  328 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESYDRLARGRGTTKKRYIGVRM------MTLTPSLSKELK-GRLRDFP----DITSGAYVIEVISKTPAAAGGLKEHDVIISINGQRISTATDVSAIIKKESSLRVVVRRGNEDIIL----------SIIPME 476

[Close]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Match: htra1a (HtrA serine peptidase 1a [Source:NCBI gene;Acc:431766])

HSP 1 Score: 62.003 bits (149), Expect = 4.856e-17
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +++G I+TN H + NK  + V L N  +Y A+I   D+  D+ALIKI+  N KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  209 SDDGLIVTNAHVVANKNRVKVELKNGASYDAKIKDVDEKADIALIKIDLPN-KLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 321

HSP 2 Score: 45.4394 bits (106), Expect = 4.856e-17
Identity = 41/170 (24.12%), Postives = 75/170 (44.12%), Query Frame = -1

Query:  138 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMD 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E  +  A+     +    G +M      + ++P ++KE +   L  +P       +  Y+  V  K+ A   GL + DV+ S++G  I + +D      +   + + + R  E + L           IIPM+
Sbjct:  328 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESYDRLARGRGTTKKRYIGVRM------MTLTPSLSKELK-GRLRDFP----DITSGAYVIEVISKTPAAAGGLKEHDVIISINGQRISTATDVSAIIKKESSLRVVVRRGNEDIIL----------TIIPME 476

[Close]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Match: htra1b (HtrA serine peptidase 1b [Source:NCBI gene;Acc:565082])

HSP 1 Score: 61.2326 bits (147), Expect = 1.032e-16
Identity = 41/114 (35.96%), Postives = 60/114 (52.63%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L     Y A+I   D+  D+ALIKI+   +KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  206 SEDGLIVTNAHVVANKHRVKVELKTGTTYDAKIKDVDEKADIALIKID-APMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 318

HSP 2 Score: 45.4394 bits (106), Expect = 1.032e-16
Identity = 40/149 (26.85%), Postives = 72/149 (48.32%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E  +  AK +   +    G +M      + ++P + KE +     +  V      +  Y+  V PK+ A   GL + DV+ S++G  I S SD +  A + ++   +++R G
Sbjct:  325 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHDRQAKGKTATKKKYIGVRM------MTLTPTLAKELKQRKNDFPDVT-----SGAYVIEVIPKTPAEVGGLKESDVIISINGQRITSASD-VSTAIKTDESLRAVVRRG 461

[Close]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Match: HTRA3 (HtrA serine peptidase 3b [Source:NCBI gene;Acc:573378])

HSP 1 Score: 57.3806 bits (137), Expect = 1.976e-16
Identity = 41/120 (34.17%), Postives = 61/120 (50.83%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLS------VRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1045
            +E G I+TN H + +   +S      V++ + + Y+A I   DK  D+A IKINP   KL  L       L  GE+V+AI S     N+V  G++S  + D K   ++     YI +DAI
Sbjct:  146 SETGLIVTNAHVVSSTTSVSGHQRLKVQMRDGDVYEATIQDIDKKSDIATIKINP-QKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLQDSDMDYIQTDAI 264

HSP 2 Score: 48.1358 bits (113), Expect = 1.976e-16
Identity = 36/157 (22.93%), Postives = 69/157 (43.95%), Query Frame = -1

Query:  174 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVK 644
            GGPL+N  GE+IG N+++       A  S    +F+ + +    KK                  G+ +  +T     +     P   +   + ++++ V P S A K G+ D D++  ++G  + STSD ++ A  ++   +  +R G    L N++
Sbjct:  271 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLNDSLGKSVKKRF---------------IGIRMLTITDALVEELKQQNPDFPD-VSSGIFVHEVVPHSPAQKGGIRDGDIIVKLNGEPLLSTSD-LKEALNQDMTLLLEVRRGNDDLLFNIE 410

[Close]

BLAST of SMED30001431 vs. Ensembl Xenopus
Match: mettl3 (methyltransferase like 3 [Source:Xenbase;Acc:XB-GENE-922807])

HSP 1 Score: 64.3142 bits (155), Expect = 4.534e-21
Identity = 41/114 (35.96%), Postives = 63/114 (55.26%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +++G I+TN H + NK  + V + +  +Y A+I   D+ LD+ALIKI+P +  L  L       L  GE+V+A+ S     N+V  G+IS       EL  K   ++YI +DAI
Sbjct:  200 SDDGLIVTNAHVLTNKQRIKVEVKDGAHYDAKIKDIDQKLDIALIKIDP-DAPLPVLMLGRSADLRPGEFVVALGSPFSLQNTVTTGIISTTQRGGKELGLKDSDMEYIQTDAI 312

HSP 2 Score: 57.3806 bits (137), Expect = 4.534e-21
Identity = 41/156 (26.28%), Postives = 76/156 (48.72%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKD---GNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E   +H ++   K LPK    G +M +    +     T++        +P      +  VY++ V P ++A  AG+ D DV+ S++G ++ ST +  +     + ++I + R  E + L
Sbjct:  319 GGPLVNLDGEVIGINTLKVTAGISFAIPSDRIRQFLAE---SHDRQTKGKMLPKKKYMGVRMLQLSSNLIRELKTRDKD------FP----DVNAGVYVFEVIPGTAAASAGMKDHDVIISLNGKMVSSTEEVSEAVRNNDTLSIVVRRGNEDIIL 461

[Close]

BLAST of SMED30001431 vs. Ensembl Xenopus
Match: psma1 (proteasome subunit alpha 1 [Source:Xenbase;Acc:XB-GENE-995831])

HSP 1 Score: 57.3806 bits (137), Expect = 3.985e-17
Identity = 40/117 (34.19%), Postives = 59/117 (50.43%), Query Frame = -2

Query:  719 GYILTNVH------EIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1036
            G I+TN H       +  +  L V+L+N ++Y+A I   DK  D+A IKI P   KL  L       L  GE+V+AI S     N+V  G++S  + D K   ++     Y+ +DAI
Sbjct:  192 GLIVTNAHVVSSSNTVSGRQYLKVQLHNGDSYEATIKDIDKKSDIATIKIYP-RKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYVQTDAI 307

HSP 2 Score: 51.2174 bits (121), Expect = 3.985e-17
Identity = 40/163 (24.54%), Postives = 71/163 (43.56%), Query Frame = -1

Query:  174 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQE------EINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVK 644
            GGPL+N  GE+IG N+++       A  S    KF+ E      + NN  KK                  G+ +  +T  F  +  ++ P   +   + +Y++ V P S A + G+ D D++  V+G  + ++ D +  A   E   +  +R G    L N++
Sbjct:  314 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITKFMTESQDKKYKANNDGKKRF---------------IGIKMLTITPSFAEEKKLHNPDFPD-VTSGIYVHEVVPNSPAQRGGIQDGDIIVKVNGRPLVTSGD-LHEAVMNESPLLLEVRRGNDDMLFNLE 459

[Close]

BLAST of SMED30001431 vs. Ensembl Xenopus
Match: zic4 (Zic family member 4 [Source:Xenbase;Acc:XB-GENE-1033015])

HSP 1 Score: 60.8474 bits (146), Expect = 2.223e-13
Identity = 37/113 (32.74%), Postives = 62/113 (54.87%), Query Frame = -2

Query:  722 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDA 1045
            + +G I+TN H + N+  + V+L N E+Y+A +   D   D+A IKINP  + L  L      ++  GE+V+A+ S     N++  G++S V     EL   +  ++YI +DA
Sbjct:   11 SPDGLIVTNAHVVANRRRVRVKLSNGESYEAAVRDVDPATDIATIKINP-KVPLPTLRLGRSAEIRQGEFVVAMGSPFSLQNTITSGIVSSVQRGGHELGLANRDMEYIQTDA 122

HSP 2 Score: 35.039 bits (79), Expect = 2.223e-13
Identity = 14/37 (37.84%), Postives = 22/37 (59.46%), Query Frame = -1

Query:  534 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQ 644
            GGPL+N  GE+IG N+++       A  S   ++F+Q
Sbjct:  130 GGPLVNLDGEVIGINTMKVVPGISFAIPSDRVREFLQ 166

[Close]

BLAST of SMED30001431 vs. Ensembl Xenopus
Match: htra1 (HtrA serine peptidase 1 [Source:NCBI gene;Acc:780187])

HSP 1 Score: 42.743 bits (99), Expect = 6.112e-8
Identity = 40/149 (26.85%), Postives = 69/149 (46.31%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNIS-IIRHG 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  N  +  +  K+    G +M     G       KE + + +  +P       +  YI  V P + A +AGL + D++ S+ G    ++S  +  A ++E   +  +IR G
Sbjct:  306 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRKFLAESHNRQSTGQGTKKKKYLGIRMMSLSQGKL-----KELK-EQVKDFP----ENTSGAYIVEVIPDTPAEEAGLKEGDIIISIGGK-SVTSSSDVSDAIKKEGTTLQLVIRRG 443

HSP 2 Score: 34.2686 bits (77), Expect = 6.112e-8
Identity = 21/62 (33.87%), Postives = 30/62 (48.39%), Query Frame = -2

Query:  719 KLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 889
            KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  238 KLPVLLLGRSEDLRPGEFVVAIGSPFSLQNTVTTGIVSTAQRGGKELGLRNSDMDYIQTDAI 299

[Close]

BLAST of SMED30001431 vs. Ensembl Xenopus
Match: htra1 (HtrA serine peptidase 1 [Source:NCBI gene;Acc:780187])

HSP 1 Score: 42.743 bits (99), Expect = 1.055e-7
Identity = 40/149 (26.85%), Postives = 69/149 (46.31%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNIS-IIRHG 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  N  +  +  K+    G +M     G       KE + + +  +P       +  YI  V P + A +AGL + D++ S+ G    ++S  +  A ++E   +  +IR G
Sbjct:  265 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRKFLAESHNRQSTGQGTKKKKYLGIRMMSLSQGKL-----KELK-EQVKDFP----ENTSGAYIVEVIPDTPAEEAGLKEGDIIISIGGK-SVTSSSDVSDAIKKEGTTLQLVIRRG 402

HSP 2 Score: 33.8834 bits (76), Expect = 1.055e-7
Identity = 21/62 (33.87%), Postives = 30/62 (48.39%), Query Frame = -2

Query:  719 KLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 889
            KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  197 KLPVLLLGRSEDLRPGEFVVAIGSPFSLQNTVTTGIVSTAQRGGKELGLRNSDMDYIQTDAI 258

[Close]

BLAST of SMED30001431 vs. Ensembl Mouse
Match: Htra4 (HtrA serine peptidase 4 [Source:MGI Symbol;Acc:MGI:3036260])

HSP 1 Score: 67.0106 bits (162), Expect = 1.071e-20
Identity = 50/154 (32.47%), Postives = 75/154 (48.70%), Query Frame = -2

Query:  719 NIVSKTVESVTSSLVHXXXXXXXXXXXXX----------VNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1135
            N ++  VE V  S+VH+ +      +             V+E+G I+TN H + N+  + V L +   Y+A +   D  LDLALIKI P + +L  L       L  GE+V+A+ S     N+V  G++S       EL  K+  I YI +DAI
Sbjct:  174 NFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQSGARYEATVKDIDHKLDLALIKIEP-DTELPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGRELGLKNSDIDYIQTDAI 326

HSP 2 Score: 53.1434 bits (126), Expect = 1.071e-20
Identity = 36/151 (23.84%), Postives = 77/151 (50.99%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  G++IG N+++       A  S   ++F+++    + +++L  + P     +     G+ + P+T     +     P   +   + V++Y V   S+A  +GL D DV+ S++G  + +T+D I+     + ++I ++R  ++L
Sbjct:  333 GGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLED----YHERQLKGKAPLQKKYL-----GLRMLPLTLNLLQEMKRQDPEFPD-VSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNDFLSIIVLRGSQTL 473

[Close]

BLAST of SMED30001431 vs. Ensembl Mouse
Match: Htra1 (HtrA serine peptidase 1 [Source:MGI Symbol;Acc:MGI:1929076])

HSP 1 Score: 62.7734 bits (151), Expect = 6.930e-18
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N   Y+A+I   D+  D+ALIKI+    KL  L      +L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  210 SEDGLIVTNAHVVTNKNRVKVELKNGATYEAKIKDVDEKADIALIKID-HQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 322

HSP 2 Score: 47.7506 bits (112), Expect = 6.930e-18
Identity = 38/151 (25.17%), Postives = 66/151 (43.71%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  +  AK +   +    G +M         S   KE +  +  +  V      +  YI  V P + A   GL + DV+ S++G  + + +D      +   +N+ + R  E +
Sbjct:  329 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAVTKKKYIGIRMMS-----LTSSKAKELKDRHRDFPDVL-----SGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVTANDVSDVIKKENTLNMVVRRGNEDI 469

[Close]

BLAST of SMED30001431 vs. Ensembl Mouse
Match: Htra3 (HtrA serine peptidase 3 [Source:MGI Symbol;Acc:MGI:1925808])

HSP 1 Score: 55.8398 bits (133), Expect = 1.606e-15
Identity = 41/120 (34.17%), Postives = 60/120 (50.00%), Query Frame = -2

Query:  719 NENGYILTNVHEIFN------KPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1045
            +E G I+TN H + +      +  L V+L N + Y+A I   DK  D+A I I+P   KL  L       L  GE+V+AI S     N+V  G++S  + D K   ++     YI +DAI
Sbjct:  187 SEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKK-KLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAI 305

HSP 2 Score: 46.595 bits (109), Expect = 1.606e-15
Identity = 35/148 (23.65%), Postives = 64/148 (43.24%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE+IG N+++       A  S    +F+ E  N H K    + +            G+ +  +T     +     P    +  + +Y+  V P S + + G+ D D++  V+G  +  +S+ +Q A   E   +  +R G
Sbjct:  312 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFI------------GIRMRTITPSLVEELKAANP-DFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSE-LQEAVLNESSLLLEVRRG 445

[Close]

BLAST of SMED30001431 vs. Ensembl Mouse
Match: Htra3 (HtrA serine peptidase 3 [Source:MGI Symbol;Acc:MGI:1925808])

HSP 1 Score: 55.8398 bits (133), Expect = 1.300e-12
Identity = 41/120 (34.17%), Postives = 60/120 (50.00%), Query Frame = -2

Query:  719 NENGYILTNVHEIFN------KPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1045
            +E G I+TN H + +      +  L V+L N + Y+A I   DK  D+A I I+P   KL  L       L  GE+V+AI S     N+V  G++S  + D K   ++     YI +DAI
Sbjct:  187 SEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHP-KKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAI 305

HSP 2 Score: 36.5798 bits (83), Expect = 1.300e-12
Identity = 17/45 (37.78%), Postives = 24/45 (53.33%), Query Frame = -1

Query:  510 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAK 644
            GGPL+N  GE+IG N+++       A  S    +F+ E  N H K
Sbjct:  312 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVK 356

[Close]

BLAST of SMED30001431 vs. Ensembl Mouse
Match: Htra2 (HtrA serine peptidase 2 [Source:MGI Symbol;Acc:MGI:1928676])

HSP 1 Score: 46.595 bits (109), Expect = 1.468e-12
Identity = 30/111 (27.03%), Postives = 58/111 (52.25%), Query Frame = -2

Query:  722 NGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVE-----LDKKSHSIKYIYSDA 1039
            +G I+TN H + ++  + VRL + + Y+A + A D + D+A ++I      L  L       +  GE+V+A+ S     N++  G++S  +     L    ++++YI +DA
Sbjct:   28 DGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQ-TKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDA 137

HSP 2 Score: 45.8246 bits (107), Expect = 1.468e-12
Identity = 37/153 (24.18%), Postives = 69/153 (45.10%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   ++F+      H  ++ N      G+Q      GV +  +T    ++  +  P +     + V I+ V   S A++AGL   DV+ ++   +  +  D  +    + ++ + I R  E+L L
Sbjct:  145 GGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFL------HRGEKKNSWFGTSGSQ--RRYIGVMMLTLTPSILIELQLREP-SFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKLAQNAEDVYEAVRTQSQLAVRIRRGSETLTL 288

[Close]

BLAST of SMED30001431 vs. UniProt/SwissProt
Match: sp|A2RT60|HTRA4_MOUSE (Serine protease HTRA4 OS=Mus musculus OX=10090 GN=Htra4 PE=2 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 6.471e-20
Identity = 50/154 (32.47%), Postives = 75/154 (48.70%), Query Frame = -2

Query:  719 NIVSKTVESVTSSLVHXXXXXXXXXXXXX----------VNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1135
            N ++  VE V  S+VH+ +      +             V+E+G I+TN H + N+  + V L +   Y+A +   D  LDLALIKI P + +L  L       L  GE+V+A+ S     N+V  G++S       EL  K+  I YI +DAI
Sbjct:  174 NFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQSGARYEATVKDIDHKLDLALIKIEP-DTELPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGRELGLKNSDIDYIQTDAI 326

HSP 2 Score: 53.1434 bits (126), Expect = 6.471e-20
Identity = 36/151 (23.84%), Postives = 77/151 (50.99%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  G++IG N+++       A  S   ++F+++    + +++L  + P     +     G+ + P+T     +     P   +   + V++Y V   S+A  +GL D DV+ S++G  + +T+D I+     + ++I ++R  ++L
Sbjct:  333 GGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLED----YHERQLKGKAPLQKKYL-----GLRMLPLTLNLLQEMKRQDPEFPD-VSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNDFLSIIVLRGSQTL 473

[Close]

BLAST of SMED30001431 vs. UniProt/SwissProt
Match: sp|D3ZKF5|HTRA4_RAT (Serine protease HTR4 OS=Rattus norvegicus OX=10116 GN=Htra4 PE=3 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 8.010e-20
Identity = 51/154 (33.12%), Postives = 73/154 (47.40%), Query Frame = -2

Query:  719 NIVSKTVESVTSSLVHXXXXXXXXXXXXX----------VNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1135
            N ++  VE V  S+VH+ +      +             V+E+G I+TN H + N+  + V L N   Y+A +   D  LDLALIKI P +  L  L       L  GE+V+A+ S     N+V  G++S       EL  K   I YI +DAI
Sbjct:  179 NFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQNGAQYEATVKDIDHKLDLALIKIEP-DTDLPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGKELGLKDSDIDYIQTDAI 331

HSP 2 Score: 51.2174 bits (121), Expect = 8.010e-20
Identity = 36/151 (23.84%), Postives = 76/151 (50.33%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  G++IG N+++       A  S   ++F    + ++ +++L  + P     + +   G+ + P+T     +     P   +   + V++Y V   S+A  +GL D DV+ S++G  + +T+D I+       ++I ++R  ++L
Sbjct:  338 GGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQF----LADYHERQLKGKAP-----LQKKYLGLRMLPLTLNLLQEMKRQDPDFPD-VSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNAFLSIIVLRGSQTL 478

[Close]

BLAST of SMED30001431 vs. UniProt/SwissProt
Match: sp|A6YFB5|HTRA1_XENLA (Serine protease HTRA1 OS=Xenopus laevis OX=8355 GN=htra1 PE=1 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 2.793e-19
Identity = 43/114 (37.72%), Postives = 60/114 (52.63%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G ILTN H + NK  L V   +   Y A+II  D+  D+ALIKI     KL  L      +L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  189 SEDGLILTNAHVVTNKHRLKVERSDGSTYDAQIIDVDEKADIALIKIK-AKGKLPVLLLGRSEELRPGEFVVAIGSPFSLQNTVTTGIVSTAQRGGKELGLRNSDMDYIQTDAI 301

HSP 2 Score: 52.7582 bits (125), Expect = 2.793e-19
Identity = 40/148 (27.03%), Postives = 70/148 (47.30%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE++G N+++       A  S   +KF+ E  N  +  +  K+    G +M     G       KE + + +  +P       +  YI  V P + A +AGL + D++ S+ G  + S+S+ +  A ++E     +IR G
Sbjct:  308 GGPLVNLDGEVVGINTLKVTAGISFAIPSDKIRKFMAESHNRQSTGQGTKKKKYLGIRMMSLSQGKL-----KELK-EQVKDFP----ENTSGAYIVEVLPDTPAEEAGLKEGDIIISISGKTVTSSSE-VSEAIKKEGTLQMVIRRG 444

[Close]

BLAST of SMED30001431 vs. UniProt/SwissProt
Match: sp|Q92743|HTRA1_HUMAN (Serine protease HTRA1 OS=Homo sapiens OX=9606 GN=HTRA1 PE=1 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 6.956e-18
Identity = 42/114 (36.84%), Postives = 62/114 (54.39%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N   Y+A+I   D+  D+ALIKI+    KL  L      +L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  210 SEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKID-HQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 322

HSP 2 Score: 50.447 bits (119), Expect = 6.956e-18
Identity = 40/153 (26.14%), Postives = 67/153 (43.79%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S   +KF+ E  +  AK +   +    G +M         S   KE +  +  +  V      +  YI  V P + A   GL + DV+ S++G  + S +D      R   +N+ + R  E + +
Sbjct:  329 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMS-----LTSSKAKELKDRHRDFPDVI-----SGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMI 471

[Close]

BLAST of SMED30001431 vs. UniProt/SwissProt
Match: sp|E1BJW1|HTRA4_BOVIN (Serine protease HTR4 OS=Bos taurus OX=9913 GN=HTRA4 PE=3 SV=1)

HSP 1 Score: 66.2402 bits (160), Expect = 1.031e-17
Identity = 42/114 (36.84%), Postives = 59/114 (51.75%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + N+  + V L +   Y+A +   D  LDLALIKI P N  L  L       L  GE+V+A+ S     N+V  G++S       EL  K   + YI +DAI
Sbjct:  215 SEDGLIVTNAHVLTNQQRIQVELQSGVQYEATVKDVDHKLDLALIKIEP-NADLPVLLLGKSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGKELGLKDSDMDYIQTDAI 327

HSP 2 Score: 46.2098 bits (108), Expect = 1.031e-17
Identity = 36/153 (23.53%), Postives = 75/153 (49.02%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  G++IG N+++       A  S   ++F+ E    H ++   K L +      +   G+ + P+T     +     P   +   + V+++ V   ++A  +GL D DV+ S++G  + +T+D I+     + +++ + R  ++L L
Sbjct:  334 GGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLAE---FHERQLKGKALSQ------KKYLGLRMLPLTMNLLQEMKRQDPEFPD-VASGVFVHEVIQGTAAESSGLKDHDVIVSINGLPVTTTTDVIEAVKANDSLSLLVRRKSQTLIL 476

[Close]

BLAST of SMED30001431 vs. TrEMBL
Match: H2ZZW4 (HtrA serine peptidase 4 OS=Latimeria chalumnae OX=7897 GN=HTRA4 PE=4 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 1.248e-20
Identity = 42/114 (36.84%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N   Y A+++  D+ LD+ALIKI P    L  L       L  GE+V+A+ S     N+V  G++S       EL  K   ++YI +DAI
Sbjct:  192 SEDGMIVTNAHVLSNKQKIKVELKNGAQYDAKVLDADQKLDIALIKIEP-ESPLPVLLLGRSSDLRPGEFVVAVGSPFSLQNTVTTGIVSTAQRGGKELGLKDSDMEYIQTDAI 304

HSP 2 Score: 61.6178 bits (148), Expect = 1.248e-20
Identity = 46/158 (29.11%), Postives = 74/158 (46.84%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYD-----NKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPLLN  GE+IG N+++       A  S   ++F+ E   +H ++   K LPK      +   GV      +  QL   + + +     D     + VYI+ V P ++A  AGL D DV+ S++G  I ST D  +     + + + + R  E + L
Sbjct:  311 GGPLLNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAE---SHDRQLKGKTLPK------KKYMGV------RMLQLSSSLIHDLKSHDQDFPDVNSGVYIFEVIPGTAAEGAGLKDRDVIISINGKTISSTEDVSEAVKNSDTLTVVVRRGKEDVVL 453

[Close]

BLAST of SMED30001431 vs. TrEMBL
Match: H2Y050 (PDZ domain-containing protein OS=Ciona intestinalis OX=7719 PE=4 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.720e-19
Identity = 38/114 (33.33%), Postives = 64/114 (56.14%), Query Frame = -2

Query:  722 NGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----EL---DKKSHSIKYIYSDA 1039
            NG I+TN H + N+  L+V+L +   ++ ++I  D+  D+A +KIN     L K+     R L  GE+V+AI S     N+V  G++S++     EL   D++   ++YI +DA
Sbjct:   57 NGLIITNAHVVGNQSALNVKLQDGREFEGQVIGIDEARDIAAVKIN--CTGLPKIPLGTTRDLRPGEWVVAIGSPLALKNTVTAGIVSNMCRAGKELGLRDEEKRDMEYIQTDA 168

HSP 2 Score: 55.8398 bits (133), Expect = 1.720e-19
Identity = 41/159 (25.79%), Postives = 70/159 (44.03%), Query Frame = -1

Query:  183 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEH-----GVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLR 644
            GGPL+N  GE+IG NS+      G A    + + F+Q+                +  Q    +H     GV +  +T E         P   +     VY++ V+P S +  AG+ + DV+  ++G  I   SD ++   + + +N SI R G ++ +R
Sbjct:  176 GGPLVNLDGEVIGINSMMASAGIGFAIPIDYVRDFLQQ---------------LEHGQQTRVQHTRRWIGVSMLSLTPEISSHLRARNPDFPD-VTTGVYVHKVTPDSPSDIAGVQNGDVIIKINGKQINGVSDVLETLKQNQVLNASICRRGRTIVVR 318

[Close]

BLAST of SMED30001431 vs. TrEMBL
Match: L0KBQ5 (Trypsin-like serine protease with C-terminal PDZ domain OS=Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1) OX=748449 GN=Halha_2567 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.174e-19
Identity = 43/113 (38.05%), Postives = 66/113 (58.41%), Query Frame = -2

Query:  722 NENGYILTNVHEIFNKPCLSVRLYN-DENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVIS----DVELDKKSHSIKYIYSDA 1045
            +++GYI+TN H I     + V L + D++Y+ +I+  D + DLA+IKINPG+ KL  +   +   L VG+  IAI +  GF  +V  GVIS     ++L K +  I  I +DA
Sbjct:  111 DQDGYIVTNNHVIDQADQIKVILSDGDKSYQGKIVGRDPVTDLAVIKINPGSEKLPVVKIGNSNNLEVGQLAIAIGNPYGFSETVTTGVISALGRQIQLQKSTGLINMIQTDA 223

HSP 2 Score: 53.5286 bits (127), Expect = 3.174e-19
Identity = 45/167 (26.95%), Postives = 78/167 (46.71%), Query Frame = -1

Query:  159 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTS---DFIQYATRREKVNISIIRHGES--LQLRNVKFTSDY 644
            GG LLN  GE+IG N+    Q  G+  +           I  +  KE+ K+L   G ++     G+Y S +  +   +Y +       +  + VYI++V   S A+K  L + D++  +D  II S +   D +Q     +K+N++I R G+   + ++  K   DY
Sbjct:  231 GGALLNSQGEVIGINTAIIEQAQGIGFA-----------IPINVVKEITKELIAKG-EVVRPWLGIYASSINSKLAKEYDL-------AVKHGVYIFNVIEGSPAFKVNLQNGDIITKIDQKIITSMARLKDILQEYQVNDKINLTIYRAGKKKEISVKLAKMPQDY 378

[Close]

BLAST of SMED30001431 vs. TrEMBL
Match: A0A0X3P1T1 (PDZ domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR139238 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 3.347e-19
Identity = 38/114 (33.33%), Postives = 64/114 (56.14%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKI--NPGNI-KLSKLDFADE-RKLNVGEYVIAISSTKGFPNSVMFGVISDVELD-KKSHSIKYIYSDAI 1045
            +++G I+TN H + +K  L V + +   + A ++A D   DLAL+++  +P  + KL ++  A     +  G++VIA+ S     N+V  GVIS VE D      +KY+ +DAI
Sbjct:  140 DDSGLIITNAHVVGHKQGLKVHMLDGRTFDARVLAVDVTSDLALVQVEADPDTLSKLPRMRLAPSLSNIRPGQFVIALGSPLMLSNTVTVGVISAVERDLGHREGLKYLQTDAI 253

HSP 2 Score: 62.3882 bits (150), Expect = 3.347e-19
Identity = 45/193 (23.32%), Postives = 80/193 (41.45%), Query Frame = -1

Query:  177 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPET------------------------------EH----GVYVSPVTKEFQLDYLIYYPVAK---ESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNV 644
            GGPL++ +GE+IG NS+      G A      Q+F++      A +      P+ G+  P T                              EH    G+ +  +T +   D  +  P  +       + V I+ V   S A +AGLL  D++ ++DG  I + ++      R E + +++IR G+ L++ +V
Sbjct:  260 GGPLVSLYGEVIGVNSMIADTGLGFAVPVDQVQRFIETSKRALANRGRGTSTPQSGSVPPTTPQAPRSWSWSWSSKPDSERNQGSVVVGPAGEHSRYLGLVMRTLTPDLAFDLALRDPFGRFTNRDVQSGVLIHGVIRGSPAERAGLLPGDIIVAIDGKQITNATEVSAAVDRSESLCLTVIRRGKRLEIPSV 452

[Close]

BLAST of SMED30001431 vs. TrEMBL
Match: A0A1W5BA00 (serine protease HTRA1-like OS=Ciona intestinalis OX=7719 GN=LOC100182899 PE=4 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 3.612e-19
Identity = 38/114 (33.33%), Postives = 64/114 (56.14%), Query Frame = -2

Query:  722 NGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----EL---DKKSHSIKYIYSDA 1039
            NG I+TN H + N+  L+V+L +   ++ ++I  D+  D+A +KIN     L K+     R L  GE+V+AI S     N+V  G++S++     EL   D++   ++YI +DA
Sbjct:  147 NGLIITNAHVVGNQSALNVKLQDGREFEGQVIGIDEARDIAAVKIN--CTGLPKIPLGTTRDLRPGEWVVAIGSPLALKNTVTAGIVSNMCRAGKELGLRDEEKRDMEYIQTDA 258

HSP 2 Score: 55.8398 bits (133), Expect = 3.612e-19
Identity = 41/159 (25.79%), Postives = 70/159 (44.03%), Query Frame = -1

Query:  183 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEH-----GVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLR 644
            GGPL+N  GE+IG NS+      G A    + + F+Q+                +  Q    +H     GV +  +T E         P   +     VY++ V+P S +  AG+ + DV+  ++G  I   SD ++   + + +N SI R G ++ +R
Sbjct:  266 GGPLVNLDGEVIGINSMMASAGIGFAIPIDYVRDFLQQ---------------LEHGQQTRVQHTRRWIGVSMLSLTPEISSHLRARNPDFPD-VTTGVYVHKVTPDSPSDIAGVQNGDVIIKINGKQINGVSDVLETLKQNQVLNASICRRGRTIVVR 408

[Close]

BLAST of SMED30001431 vs. Ensembl Cavefish
Match: htra4 (serine protease HTRA1-like [Source:NCBI gene;Acc:103028201])

HSP 1 Score: 61.2326 bits (147), Expect = 5.836e-20
Identity = 41/114 (35.96%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G+I+TN H + NK  + V L N  +Y A     D+ LD+ALIKI+     L  L       L  GE+V+A+ S     N+V  G+IS       EL  ++  ++YI +DAI
Sbjct:  219 SEDGWIVTNAHVLSNKQRIKVELNNGVHYDATAKDVDQKLDIALIKID-SEEPLPVLLLGRSSDLRPGEFVVAVGSPFSLQNTVTTGIISTTQRGGHELGLQNSDMEYIQTDAI 331

HSP 2 Score: 55.8398 bits (133), Expect = 5.836e-20
Identity = 40/158 (25.32%), Postives = 71/158 (44.94%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYD-----NKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  G++IG N+++       A  S   Q+F+ +      K          G   P+     Y+    + FQL   +   + +   D     + VY+Y V P ++A  AGL++ DV+ +++G +  +T D        E ++I + R  E + L
Sbjct:  338 GGPLVNLDGDVIGINTLKVTAGISFAIPSDRIQQFLADSYERQRK----------GRTKPKKR---YIG--VRMFQLTPSLIRELKERESDFPDVSSGVYVYEVIPGTAASSAGLMNHDVIITINGQLAQTTEDVSHAVQSGEPLSIVVRRANEDVTL 480

[Close]

BLAST of SMED30001431 vs. Ensembl Cavefish
Match: htra1b (serine protease HTRA1B-like [Source:NCBI gene;Acc:103041103])

HSP 1 Score: 61.6178 bits (148), Expect = 9.173e-20
Identity = 41/114 (35.96%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L +   Y A+I   D+  D+ALIKI+   +KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  201 SEDGLIVTNAHVVANKHRVKVELKSGATYDAKIKDVDEKADIALIKID-APMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 313

HSP 2 Score: 54.6842 bits (130), Expect = 9.173e-20
Identity = 41/152 (26.97%), Postives = 73/152 (48.03%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPV----TKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E  +  AK +L  +    G +M      + ++P      KE Q D+            +  Y+  V PK+ A   GL + DV+ S++G  I S SD +  + ++++   +++R G
Sbjct:  320 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLTESHDRQAKGKLPMKKKYIGVRM------MTLTPTLAKELKERQSDF--------PDVTSGAYVIEVIPKTPAEVGGLQESDVIISINGQRITSASD-VSASIKKDESLRTVVRRG 456

[Close]

BLAST of SMED30001431 vs. Ensembl Cavefish
Match: htra1a (serine protease HTRA1A [Source:NCBI gene;Acc:103042183])

HSP 1 Score: 63.5438 bits (153), Expect = 1.022e-16
Identity = 42/114 (36.84%), Postives = 63/114 (55.26%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +++G I+TN H + NK  + V L N  +Y A+I   D+  D+ALIKI+  + KLS L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  211 SDDGLIVTNAHVVANKNRVKVELKNGASYDAKIKDVDEKSDIALIKIDSPS-KLSVLSLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 323

HSP 2 Score: 42.743 bits (99), Expect = 1.022e-16
Identity = 40/170 (23.53%), Postives = 76/170 (44.71%), Query Frame = -1

Query:  138 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMD 644
            GGPL+N  GE+IG N+++       A  S    +F+ E  +  A+     +    G +M      + ++P + KE +     +  +      +  Y+  V  K+ A  AGL + DV+ S++   I + +D +  A +++     ++R G      +V  T     +IPM+
Sbjct:  330 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKITQFLSESYDRQARGRGGVKKKYIGVRM------MTLTPALAKELKAKQRDFPDIT-----SGAYVIEVITKTPAAVAGLKEHDVIISINSQRISTATD-VSTAIKKDSTLRMVVRRGN----EDVMLT-----VIPME 478

[Close]

BLAST of SMED30001431 vs. Ensembl Cavefish
Match: HTRA3 (HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406])

HSP 1 Score: 55.8398 bits (133), Expect = 1.363e-16
Identity = 41/120 (34.17%), Postives = 59/120 (49.17%), Query Frame = -2

Query:  719 NENGYILTNVH------EIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1045
            +E G I+TN H       +  +  L V++++   Y+A I   DK  D+A IKIN    KL  L       L  GE+V+AI S     N+V  G++S  + D K   I+     YI +DAI
Sbjct:  184 SETGLIVTNAHVVSSTTAVSGRQQLKVQMHDGNVYEATIKDIDKKSDIATIKIN-TQKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGIQDSDMDYIQTDAI 302

HSP 2 Score: 49.6766 bits (117), Expect = 1.363e-16
Identity = 37/151 (24.50%), Postives = 67/151 (44.37%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  GE+IG N+++       A  S    +F+ + +   +K  + K+             G+ +  +T E  +D L           + +Y++ V P S A K G+ D D++  ++G  + STSD     T    + + + R  + L
Sbjct:  309 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLNDSMGKQSK--VKKRF-----------IGIRMLTIT-EALVDELKQQNPDFPDVTSGIYVHEVVPHSPAQKGGIKDGDIIVKLNGQPLMSTSDLKDALTEDTALLLEVRRGNDDL 445

[Close]

BLAST of SMED30001431 vs. Ensembl Cavefish
Match: si:dkey-33c12.12 (serine protease HTRA2, mitochondrial [Source:NCBI gene;Acc:103043568])

HSP 1 Score: 59.6918 bits (143), Expect = 1.855e-15
Identity = 36/113 (31.86%), Postives = 60/113 (53.10%), Query Frame = -2

Query:  722 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDA 1045
            + +G I+TN H + NK  + V+L + E Y A +   D+  D+A IKI P +  L  L  A   ++  GE+V+A+ S     N++  G++S       EL   + ++ YI +DA
Sbjct:  174 SSDGLIVTNAHVVANKRDVRVKLTSGETYNAVVQDVDQAADIATIKIQPKH-PLPTLRLAQSSEVRQGEFVVAMGSPFALRNTITSGIVSSTQRGSKELGLSNPNMDYIQTDA 285

HSP 2 Score: 41.9726 bits (97), Expect = 1.855e-15
Identity = 39/156 (25.00%), Postives = 68/156 (43.59%), Query Frame = -1

Query:  192 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEH-----GVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESL 644
            GGPL+N  GE+IG N+++       A  S   + F            LN+   K  +   E+       GV +  +T     +  +  P+  +   + + I+ +   S A++AG+   D+V  V+G +  +TS+ I  A R       ++R GE L
Sbjct:  293 GGPLINLDGEVIGINTMKVTAGISFAIPSDRVRVF------------LNQAADKKKSWFSESTTKRRYVGVMMLTLTPSIIAELKMRDPLFPD-VTHGILIHRIISGSPAHRAGMKPGDIVLEVNG-VKVNTSEEIYNAVRSSDSIKMVVRRGEDL 434

[Close]

BLAST of SMED30001431 vs. Ensembl Sea Lamprey
Match: HTRA1 (HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476])

HSP 1 Score: 67.0106 bits (162), Expect = 2.350e-13
Identity = 40/114 (35.09%), Postives = 63/114 (55.26%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V+L++ E+Y+A ++  D+  D+A I+I     KL  L  A   +L  GE+V+AI S     N+V  G++S       EL  +     YI +DAI
Sbjct:   52 SEDGVIVTNAHVVVNKRYVKVQLHDGESYEASVVDADEKADIATIRIK-AKQKLPVLRLARSAELRPGEFVVAIGSPFKLQNTVTTGIVSTAQRGGQELGLEDSDADYIQTDAI 164

[Close]

BLAST of SMED30001431 vs. Ensembl Sea Lamprey
Match: HTRA1 (HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476])

HSP 1 Score: 63.5438 bits (153), Expect = 4.390e-12
Identity = 41/132 (31.06%), Postives = 64/132 (48.48%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKIN------------------PGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V+L++ E+Y+A ++  D+  D+A I+I                   P   KL  L  A   +L  GE+V+AI S     N+V  G++S       EL  +     YI +DAI
Sbjct:   50 SEDGVIVTNAHVVVNKRYVKVQLHDGESYEASVVDADEKADIATIRIKAKVTCRLRSSADVAAAPLPSQQKLPVLRLARSAELRPGEFVVAIGSPFKLQNTVTTGIVSTAQRGGQELGLEDSDADYIQTDAI 181

[Close]

BLAST of SMED30001431 vs. Ensembl Sea Lamprey
Match: HTRA1 (HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HGNC:9476])

HSP 1 Score: 56.6102 bits (135), Expect = 1.387e-11
Identity = 42/119 (35.29%), Postives = 62/119 (52.10%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCL---SVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVE-------LDKKSHSIKYIYSDAI 1045
            +E+G ILTN H + +K  L    V+L N + Y+A  +  D   ++A+IKIN    KL  L  A   +L  GE+V+AI S     N+V  G++S  +       LD   H   YI +DA+
Sbjct:  141 SEDGLILTNAHVVTHKRDLVAVKVQLTNGDTYEAWPLHVDMHANIAVIKIN-AKQKLPVLRLARSAELRPGEFVVAIGSPFKLQNTVTTGIVSTAQRGGQELGLDDSDHD--YIQTDAM 256

HSP 2 Score: 30.0314 bits (66), Expect = 1.387e-11
Identity = 9/19 (47.37%), Postives = 15/19 (78.95%), Query Frame = -1

Query:  591 VGGPLLNFHGEIIGFNSIR 647
             GGPL+N  GE++G N+++
Sbjct:  262 AGGPLVNLDGEVVGINTLK 280

[Close]

BLAST of SMED30001431 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002935.1 (pep scaffold:Pmarinus_7.0:GL478486:180388:188108:-1 gene:ENSPMAG00000002674.1 transcript:ENSPMAT00000002935.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.9802 bits (110), Expect = 1.739e-6
Identity = 28/91 (30.77%), Postives = 46/91 (50.55%), Query Frame = -2

Query:  782 NENGYILTNVHEIFNKPCLSV---RLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGV 1045
            ++ G I+TN H +       V    L    +Y+AE+   D  +D+A I+I+P +  L+ L      +L  GE+V+AI S     N+V  G+
Sbjct:   56 SDEGLIVTNAHVVGGGGATRVVMVTLRGGRSYEAEVTDVDTKVDIATIRIHPQH-PLAVLQLGRSSELRPGEFVVAIGSPFALQNTVTTGM 145

[Close]

BLAST of SMED30001431 vs. Ensembl Medaka
Match: HTRA3 (HtrA serine peptidase 3 [Source:NCBI gene;Acc:101162823])

HSP 1 Score: 65.855 bits (159), Expect = 1.074e-21
Identity = 44/119 (36.97%), Postives = 62/119 (52.10%), Query Frame = -2

Query:  719 ENGYILTNVHEIF------NKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIK-----YIYSDAI 1042
            ENG I+TN H +        +  L V+++N + Y+A I   DK  D+A IKINP  IKL  L       L  GE+V+AI S     N+V  G++S  + D K   ++     YI +DAI
Sbjct:  193 ENGLIVTNAHVVSSSSPVSGQQHLKVQMHNGDVYEATIKDIDKKSDIATIKINP-QIKLPVLFLGQSADLRPGEFVVAIGSPFALQNTVTTGIVSSAQRDGKELGLRDSDMDYIQTDAI 310

HSP 2 Score: 57.3806 bits (137), Expect = 1.074e-21
Identity = 43/168 (25.60%), Postives = 72/168 (42.86%), Query Frame = -1

Query:  174 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEF-QLDYLIYYPVAKESYDNK----------VYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVK 644
            GGPL+N  GE+IG N+++       A  S    +F+ + +N H+K+                     + P+ K F  +  L   P   E    +          +Y++ V P S A K G+ D D++  ++G  + STSD +Q A + E   +  IR      L N++
Sbjct:  317 GGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLNDSLNKHSKE---------------------LRPIKKRFIGIRMLTITPALIEELKQQNSDFPNVTSGIYVHEVVPHSPAQKGGIKDGDIIVKLNGKPLTSTSD-LQAALQEETALLLEIRRDNDDLLFNIE 462

[Close]

BLAST of SMED30001431 vs. Ensembl Medaka
Match: htra1a (serine protease HTRA1A [Source:NCBI gene;Acc:105355810])

HSP 1 Score: 63.5438 bits (153), Expect = 1.086e-18
Identity = 42/114 (36.84%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L N  +Y A+I   D+  D+ALIKI+    KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  206 SEDGQIVTNAHVVANKHRVKVELKNGASYDAKIKDVDEKADIALIKID-APTKLPVLLLGHSSDLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 318

HSP 2 Score: 49.6766 bits (117), Expect = 1.086e-18
Identity = 36/149 (24.16%), Postives = 71/149 (47.65%), Query Frame = -1

Query:  201 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHG 644
            GGPL+N  GE+IG N+++       A  S   ++F+ E  +  ++   + +    G +M      + ++P + KE +  +  +  +      +  Y+  V  K+ A   GL D DV+ S++G  I + +D +    +R+ V   ++R G
Sbjct:  325 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESYDRQSRGRKDAKKKYIGVRM------MTLTPALAKELKTRHRDFPDIT-----SGAYVMEVIAKTPAANGGLKDHDVIISINGQRISTATD-VSATIKRDDVLRIVVRRG 461

[Close]

BLAST of SMED30001431 vs. Ensembl Medaka
Match: htra1b (HtrA serine peptidase 1 [Source:NCBI gene;Acc:101160199])

HSP 1 Score: 62.003 bits (149), Expect = 1.160e-16
Identity = 42/114 (36.84%), Postives = 61/114 (53.51%), Query Frame = -2

Query:  719 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDV-----ELDKKSHSIKYIYSDAI 1045
            +E+G I+TN H + NK  + V L +   Y A+I   D+  D+ALIKI+  N KL  L       L  GE+V+AI S     N+V  G++S       EL  ++  + YI +DAI
Sbjct:  206 SEDGLIVTNAHVVANKHRVKVELKSGATYDAKIKDIDEKADIALIKIDTPN-KLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAI 318

HSP 2 Score: 44.2838 bits (103), Expect = 1.160e-16
Identity = 39/158 (24.68%), Postives = 66/158 (41.77%), Query Frame = -1

Query:  186 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSP-----VTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQL 644
            GGPL+N  GE+IG N+++       A  S    +F+ E  +  AK                T H +  SP     + KE +  +  +         +  Y+  V  ++ A  AGL + DV+ S++G  I S +D      R + + + + R  E + L
Sbjct:  325 GGPLVNLDGEVIGINTLKVTAGISFAIPSDKILQFLAESHDRQAKGL--------------TRHHIS-SPFSAVRLAKELKARHPDF-----PDLTSGAYVMEVIGRTPAEAAGLKERDVIISINGEHITSANDVSTTIKREQNLRMVVRRGNEDVML 462

[Close]

BLAST of SMED30001431 vs. Ensembl Medaka
Match: si:dkey-33c12.12 (serine protease HTRA2, mitochondrial-like [Source:NCBI gene;Acc:101174474])

HSP 1 Score: 59.6918 bits (143), Expect = 6.451e-15
Identity = 35/113 (30.97%), Postives = 58/113 (51.33%), Query Frame = -2

Query:  722 NENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKS-----HSIKYIYSDA 1045
            + +G I+TN H + NK  + V+L N + Y A +   D + D+A IKI   N  L  L       +  GE+V+A+ S     N++  G++S  + D K       +++YI +DA
Sbjct:  165 SSDGLIVTNAHVVANKRGVRVKLTNGDMYHASVQDVDPVADIATIKITTKN-PLPTLKLGQSSDIRQGEFVVAMGSPFALRNTITSGIVSSAQRDSKELGLSNPNMEYIQTDA 276

HSP 2 Score: 40.4318 bits (93), Expect = 6.451e-15
Identity = 34/155 (21.94%), Postives = 72/155 (46.45%), Query Frame = -1

Query:  183 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEH-GVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLR 644
            GGPL+N  GE+IG N+++       A  S   + F+     + A K+    +   G    +  + GV +  +T     +  +  P+   +  + + I+ V   S A +AG+L  D+V  ++G  + ++ +  +     +++ + + R  E L+L+
Sbjct:  284 GGPLINLDGEVIGINTMKVTAGISFAIPSDRLKIFL-----DQAAKKTKSSV---GESRTKARYIGVMMLTLTPSIITELQLRDPMF-PNVTHGILIHRVIIGSPASRAGMLAGDIVVEINGVKVNTSEEIYKAVRSSDRITMLVQRGKELLRLQ 429

[Close]

BLAST of SMED30001431 vs. Planmine SMEST
Match: SMESG000017614.1 (SMESG000017614.1)

HSP 1 Score: 382.874 bits (982), Expect = 0.000e+0
Identity = 185/186 (99.46%), Postives = 185/186 (99.46%), Query Frame = -1

Query:   90 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDLVSRSSKIFDTI 647
            VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLD VSRSSKIFDTI
Sbjct:  193 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDQVSRSSKIFDTI 378

HSP 2 Score: 301.982 bits (772), Expect = 0.000e+0
Identity = 187/188 (99.47%), Postives = 188/188 (100.00%), Query Frame = -2

Query:  710 MTASGVTYYAGKIINIQKVSMSKIKTNVLAXXXXXXXXXXXXXXSMNIVSKTVESVTSSLVHXXXXXXXXXXXXXVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKV 1273
            MTASGVTYYAGKIINIQKVSMSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINK+
Sbjct:    1 MTASGVTYYAGKIINIQKVSMSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKI 188

[Close]

BLAST of SMED30001431 vs. Planmine SMEST
Match: SMESG000017614.1 (SMESG000017614.1)

HSP 1 Score: 382.489 bits (981), Expect = 0.000e+0
Identity = 185/186 (99.46%), Postives = 185/186 (99.46%), Query Frame = -1

Query:   90 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDLVSRSSKIFDTI 647
            VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLD VSRSSKIFDTI
Sbjct:  217 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDQVSRSSKIFDTI 402

HSP 2 Score: 348.591 bits (893), Expect = 0.000e+0
Identity = 210/212 (99.06%), Postives = 211/212 (99.53%), Query Frame = -2

Query:  710 MNIIKSLKCFVNLHKRSFKAICFVMTASGVTYYAGKIINIQKVSMSKIKTNVLAXXXXXXXXXXXXXXSMNIVSKTVESVTSSLVHXXXXXXXXXXXXXVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKV 1345
            MNIIK LKCFVNLHKRSFKAICFVMTASGVTYYAGKIINIQKVSMSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINK+
Sbjct:    1 MNIIKLLKCFVNLHKRSFKAICFVMTASGVTYYAGKIINIQKVSMSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKI 212

[Close]

BLAST of SMED30001431 vs. Planmine SMEST
Match: SMESG000017614.1 (SMESG000017614.1)

HSP 1 Score: 382.104 bits (980), Expect = 2.780e-178
Identity = 185/186 (99.46%), Postives = 185/186 (99.46%), Query Frame = -1

Query:   90 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDLVSRSSKIFDTI 647
            VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLD VSRSSKIFDTI
Sbjct:  173 VGGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEINNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKFTSDYEKIIPMDSYLDQVSRSSKIFDTI 358

HSP 2 Score: 263.462 bits (672), Expect = 2.780e-178
Identity = 167/168 (99.40%), Postives = 168/168 (100.00%), Query Frame = -2

Query:  710 MSKIKTNVLAXXXXXXXXXXXXXXSMNIVSKTVESVTSSLVHXXXXXXXXXXXXXVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKV 1213
            MSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINK+
Sbjct:    1 MSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVCICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELDKKSHSIKYIYSDAINKI 168

[Close]

BLAST of SMED30001431 vs. Planmine SMEST
Match: SMESG000006679.1 (SMESG000006679.1)

HSP 1 Score: 107.457 bits (267), Expect = 1.798e-40
Identity = 68/187 (36.36%), Postives = 108/187 (57.75%), Query Frame = -2

Query:  719 SGVTYYAGKIINIQKVSMSKIKTNVLAXXXXXXXXXXXXXXSMNIVSKTVESVTSSLVHXXXXXXXXXXXXXVN----ENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELD-KKSHSIKYIYSDAI 1264
            SGV+YY  K   +  VS S + + + A ++ S +++ +     N ++  VE++T S+V + + G  +           ++GYILTN H +   P +SV L + + ++ E+IA D+  DLAL+K+NPG IKL  L FA+  KL  GE+VIA+ S     NSV  GV+S V+ D   S  ++Y+ +DAI
Sbjct:    3 SGVSYYISKNRKLNNVSTSSLTSLITANAATSRQDQINS---FNFIADVVETITPSVVSITVGGSLLGVSFGSGFIVEDSGYILTNAHVVARNPYVSVTLSDGQKFQGEVIAMDRSSDLALVKVNPGKIKLQSLRFAEISKLRAGEFVIALGSPMTLSNSVTVGVVSAVQRDLGHSKGLRYVQTDAI 186

HSP 2 Score: 78.1814 bits (191), Expect = 1.798e-40
Identity = 49/167 (29.34%), Postives = 87/167 (52.10%), Query Frame = -1

Query:  177 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEI-----------NNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNV 644
            GGPL+N +GE+IG N++     FG A  S  C +FV+  I           N +     + +L  + N+      G+ +  +T +   +  + +P         V I+SV   S A+K+G+L  D++ESV+G I++ST++F     +  +++I +IR G+ + L+NV
Sbjct:  193 GGPLVNLYGEVIGVNTMMVSTGFGFAIPSNHCNQFVKLAIGSSRSGGGLGDNTYDTNRSSVRLDSNNNKY----MGIVMGSLTPQMAYESKMNHPEYLVHPTTGVVIHSVFQLSPAHKSGILPGDIIESVNGTIVHSTAEFSAALAQYNELDIVLIRKGQRVLLKNV 355

[Close]

BLAST of SMED30001431 vs. Planmine SMEST
Match: SMESG000006679.1 (SMESG000006679.1)

HSP 1 Score: 107.071 bits (266), Expect = 2.401e-40
Identity = 67/188 (35.64%), Postives = 108/188 (57.45%), Query Frame = -2

Query:  719 SGVTYYAGKIINIQKVSMSKIKTNVLAXXXXXXXXXXXXXXSMNIVSKTVESVTSSLVHXXXXXXXXXXXXXVN-----ENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLALIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVELD-KKSHSIKYIYSDAI 1264
            SGV+YY  K   +  VS S + + + A ++ S +++ +     N ++  VE++T S+V + +    +      +     ++GYILTN H +   P +SV L + + ++ E+IA D+  DLAL+K+NPG IKL  L FA+  KL  GE+VIA+ S     NSV  GV+S V+ D   S  ++Y+ +DAI
Sbjct:    3 SGVSYYISKNRKLNNVSTSSLTSLITANAATSRQDQINS---FNFIADVVETITPSVVSITVGSGSLLGVSFGSGFIVEDSGYILTNAHVVARNPYVSVTLSDGQKFQGEVIAMDRSSDLALVKVNPGKIKLQSLRFAEISKLRAGEFVIALGSPMTLSNSVTVGVVSAVQRDLGHSKGLRYVQTDAI 187

HSP 2 Score: 78.1814 bits (191), Expect = 2.401e-40
Identity = 49/167 (29.34%), Postives = 87/167 (52.10%), Query Frame = -1

Query:  177 GGPLLNFHGEIIGFNSIRTFQRFGLACSSIFCQKFVQEEI-----------NNHAKKELNKQLPKDGNQMPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKAGLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNV 644
            GGPL+N +GE+IG N++     FG A  S  C +FV+  I           N +     + +L  + N+      G+ +  +T +   +  + +P         V I+SV   S A+K+G+L  D++ESV+G I++ST++F     +  +++I +IR G+ + L+NV
Sbjct:  194 GGPLVNLYGEVIGVNTMMVSTGFGFAIPSNHCNQFVKLAIGSSRSGGGLGDNTYDTNRSSVRLDSNNNKY----MGIVMGSLTPQMAYESKMNHPEYLVHPTTGVVIHSVFQLSPAHKSGILPGDIIESVNGTIVHSTAEFSAALAQYNELDIVLIRKGQRVLLKNV 356

The following BLAST results are available for this feature:

BLAST of SMED30001431 vs. Ensembl Human
BLAST of SMED30001431 vs. Ensembl Celegans
BLAST of SMED30001431 vs. Ensembl Fly
BLAST of SMED30001431 vs. Ensembl Zebrafish
BLAST of SMED30001431 vs. Ensembl Xenopus
BLAST of SMED30001431 vs. Ensembl Mouse
BLAST of SMED30001431 vs. UniProt/SwissProt
BLAST of SMED30001431 vs. TrEMBL
BLAST of SMED30001431 vs. Ensembl Cavefish
BLAST of SMED30001431 vs. Ensembl Sea Lamprey
BLAST of SMED30001431 vs. Ensembl Yeast
BLAST of SMED30001431 vs. Ensembl Nematostella
BLAST of SMED30001431 vs. Ensembl Medaka
BLAST of SMED30001431 vs. Planmine SMEST

BLAST of SMED30001431 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HTRA1	2.022e-19	36.84	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA1	1.589e-18	36.84	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA4	4.966e-18	31.37	HtrA serine peptidase 4 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA3	4.903e-15	35.00	HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA2	1.400e-11	27.03	HtrA serine peptidase 2 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of SMED30001431 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30001431 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
HtrA2	4.307e-11	35.96	gene:FBgn0038233 transcript:FBtr0082987	[more]
HtrA2	4.307e-11	35.96	gene:FBgn0038233 transcript:FBtr0330045	[more]

BLAST of SMED30001431 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
htra4	4.779e-21	36.84	HtrA serine peptidase 4 [Source:ZFIN;Acc:ZDB-GENE-...	[more]
htra1a	4.699e-17	36.84	HtrA serine peptidase 1a [Source:NCBI gene;Acc:431...	[more]
htra1a	4.856e-17	36.84	HtrA serine peptidase 1a [Source:NCBI gene;Acc:431...	[more]
htra1b	1.032e-16	35.96	HtrA serine peptidase 1b [Source:NCBI gene;Acc:565...	[more]
HTRA3	1.976e-16	34.17	HtrA serine peptidase 3b [Source:NCBI gene;Acc:573...	[more]

BLAST of SMED30001431 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mettl3	4.534e-21	35.96	methyltransferase like 3 [Source:Xenbase;Acc:XB-GE...	[more]
psma1	3.985e-17	34.19	proteasome subunit alpha 1 [Source:Xenbase;Acc:XB-...	[more]
zic4	2.223e-13	32.74	Zic family member 4 [Source:Xenbase;Acc:XB-GENE-10...	[more]
htra1	6.112e-8	26.85	HtrA serine peptidase 1 [Source:NCBI gene;Acc:7801...	[more]
htra1	1.055e-7	26.85	HtrA serine peptidase 1 [Source:NCBI gene;Acc:7801...	[more]

BLAST of SMED30001431 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Htra4	1.071e-20	32.47	HtrA serine peptidase 4 [Source:MGI Symbol;Acc:MGI...	[more]
Htra1	6.930e-18	36.84	HtrA serine peptidase 1 [Source:MGI Symbol;Acc:MGI...	[more]
Htra3	1.606e-15	34.17	HtrA serine peptidase 3 [Source:MGI Symbol;Acc:MGI...	[more]
Htra3	1.300e-12	34.17	HtrA serine peptidase 3 [Source:MGI Symbol;Acc:MGI...	[more]
Htra2	1.468e-12	27.03	HtrA serine peptidase 2 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of SMED30001431 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|A2RT60\|HTRA4_MOUSE	6.471e-20	32.47	Serine protease HTRA4 OS=Mus musculus OX=10090 GN=...	[more]
sp\|D3ZKF5\|HTRA4_RAT	8.010e-20	33.12	Serine protease HTR4 OS=Rattus norvegicus OX=10116...	[more]
sp\|A6YFB5\|HTRA1_XENLA	2.793e-19	37.72	Serine protease HTRA1 OS=Xenopus laevis OX=8355 GN...	[more]
sp\|Q92743\|HTRA1_HUMAN	6.956e-18	36.84	Serine protease HTRA1 OS=Homo sapiens OX=9606 GN=H...	[more]
sp\|E1BJW1\|HTRA4_BOVIN	1.031e-17	36.84	Serine protease HTR4 OS=Bos taurus OX=9913 GN=HTRA...	[more]

BLAST of SMED30001431 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H2ZZW4	1.248e-20	36.84	HtrA serine peptidase 4 OS=Latimeria chalumnae OX=...	[more]
H2Y050	1.720e-19	33.33	PDZ domain-containing protein OS=Ciona intestinali...	[more]
L0KBQ5	3.174e-19	38.05	Trypsin-like serine protease with C-terminal PDZ d...	[more]
A0A0X3P1T1	3.347e-19	33.33	PDZ domain-containing protein OS=Schistocephalus s...	[more]
A0A1W5BA00	3.612e-19	33.33	serine protease HTRA1-like OS=Ciona intestinalis O...	[more]

BLAST of SMED30001431 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
htra4	5.836e-20	35.96	serine protease HTRA1-like [Source:NCBI gene;Acc:1...	[more]
htra1b	9.173e-20	35.96	serine protease HTRA1B-like [Source:NCBI gene;Acc:...	[more]
htra1a	1.022e-16	36.84	serine protease HTRA1A [Source:NCBI gene;Acc:10304...	[more]
HTRA3	1.363e-16	34.17	HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HG...	[more]
si:dkey-33c12.12	1.855e-15	31.86	serine protease HTRA2, mitochondrial [Source:NCBI ...	[more]

BLAST of SMED30001431 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
HTRA1	2.350e-13	35.09	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA1	4.390e-12	31.06	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HG...	[more]
HTRA1	1.387e-11	35.29	HtrA serine peptidase 1 [Source:HGNC Symbol;Acc:HG...	[more]
ENSPMAT00000002935.1	1.739e-6	30.77	pep scaffold:Pmarinus_7.0:GL478486:180388:188108:-...	[more]

BLAST of SMED30001431 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30001431 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SMED30001431 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
HTRA3	1.074e-21	36.97	HtrA serine peptidase 3 [Source:NCBI gene;Acc:1011...	[more]
htra1a	1.086e-18	36.84	serine protease HTRA1A [Source:NCBI gene;Acc:10535...	[more]
htra1b	1.160e-16	36.84	HtrA serine peptidase 1 [Source:NCBI gene;Acc:1011...	[more]
si:dkey-33c12.12	6.451e-15	30.97	serine protease HTRA2, mitochondrial-like [Source:...	[more]

BLAST of SMED30001431 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000017614.1	0.000e+0	99.46	SMESG000017614.1	[more]
SMESG000017614.1	0.000e+0	99.46	SMESG000017614.1	[more]
SMESG000017614.1	2.780e-178	99.46	SMESG000017614.1	[more]
SMESG000006679.1	1.798e-40	36.36	SMESG000006679.1	[more]
SMESG000006679.1	2.401e-40	35.64	SMESG000006679.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30001431 ID=SMED30001431|Name=SMED30001431|organism=Schmidtea mediterranea sexual|type=transcript|length=1367bp
TTTTTTTACTATAAAAACAATTTTATTTTAATTTAAATAATACATAAAAA
TTTAGAATAAGTAACACACAATTGGAATATTTTGTTTTAAATTGTATCGA
AAATTTTCGATGACCGTGACACTAGATCAAGATAGGAATCCATTGGAATG
ATCTTTTCATAATCAGAGGTAAATTTGACATTTCGTAATTGTAAACTTTC
CCCATGGCGTATTATTGAGATGTTCACTTTTTCACGACGAGTCGCATATT
GGATGAAATCACTTGTAGAGTATATAATATTACCATCGACTGACTCGACA
ACGTCCAAATCAAGAAGCCCGGCTTTGTAAGCTGAAGATTTAGGAGAAAC
TGAATAAATATATACTTTATTATCATATGATTCTTTCGCCACTGGATAAT
ATATTAGGTAGTCTAACTGAAACTCCTTTGTAACTGGACTTACGTAGACA
CCGTGCTCGGTTTCAGGCATTTGATTTCCATCTTTTGGCAATTGTTTATT
TAATTCTTTTTTAGCATGATTATTAATTTCTTCTTGGACAAATTTTTGAC
AAAAAATACTCGAACATGCCAAACCAAAACGTTGAAAGGTTCTTATTGAA
TTGAAACCGATTATCTCTCCGTGGAAATTTAATAGCGGACCCCCGACAAA
AAACCTAATTATCTAAAAATTCCTCAAAAACCGGCTGGTTAATATTCAAA
CTAATAAAATACTTTGTTAATTGCGTCGGAATAAATATATTTGATAGAAT
GTGATTTTTTATCTAATTCAACATCGGATATAACCCCAAACATTACAGAA
TTAGGAAATCCTTTCGTGCTACTAATTGCAATGACATATTCTCCCACGTT
CAATTTTCTTTCATCTGCGAAATCTAGTTTACTTAATTTTATATTTCCGG
GATTTATTTTAATTAAGGCCAAATCGAGCATTTTATCGCACGCTATTATT
TCGGCTTTGTAATTTTCATCGTTATACAATCTCACAGATAAGCAAGGTTT
ATTGAAAATTTCATGAACATTTGTTAGAATATAACCATTTTCATTAACAA
TCACTCCTGAGCAGATACAGACTCCACATATGCAAACATGTACAAGACTC
GAAGTAACAGATTCCACTGTTTTGCTAACTATATTCATTGAATCAATGTC
ATCCTTTTTTTCTTTTAAACTTTTTGAGCTTTTTGCCAAAACATTGGTCT
TTATTTTTGACATACTTACTTTCTGTATATTTATAATCTTTCCCGCGTAA
TAAGTGACTCCACTAGCCGTCATAACAAAACAAATTGCTTTGAAGGATCT
TTTATGTAGATTGACAAAACACTTCAGTGACTTTATGATATTCATTATCA
AATCAAAAATAATATTG

protein sequence of SMED30001431-orf-1

>SMED30001431-orf-1 ID=SMED30001431-orf-1|Name=SMED30001431-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=128bp
MPETEHGVYVSPVTKEFQLDYLIYYPVAKESYDNKVYIYSVSPKSSAYKA
GLLDLDVVESVDGNIIYSTSDFIQYATRREKVNISIIRHGESLQLRNVKF
TSDYEKIIPMDSYLDLVSRSSKIFDTI*

protein sequence of SMED30001431-orf-2

>SMED30001431-orf-2 ID=SMED30001431-orf-2|Name=SMED30001431-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=222bp
NIIFDLIMNIIKSLKCFVNLHKRSFKAICFVMTASGVTYYAGKIINIQKV
SMSKIKTNVLAKSSKSLKEKKDDIDSMNIVSKTVESVTSSLVHVCICGVC
ICSGVIVNENGYILTNVHEIFNKPCLSVRLYNDENYKAEIIACDKMLDLA
LIKINPGNIKLSKLDFADERKLNVGEYVIAISSTKGFPNSVMFGVISDVE
LDKKSHSIKYIYSDAINKVFY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **INTERPRO**
Term	Definition
IPR001940	Peptidase_S1C
IPR009003	Peptidase_S1_PA
IPR001478	PDZ

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis

Vocabulary: **molecular function**
Term	Definition
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001940	Peptidase S1C	PRINTS	PR00834	PROTEASES2C	coord: 174..198 score: 37.07 coord: 132..152 score: 27.99 coord: 111..123 score: 46.72
None	No IPR available	PFAM	PF13365	Trypsin_2	coord: 102..201 e-value: 2.2E-10 score: 41.6
None	No IPR available	GENE3D	G3DSA:2.40.10.120		coord: 68..218 e-value: 1.1E-24 score: 89.0
None	No IPR available	PANTHER	PTHR22939	SERINE PROTEASE FAMILY S1C HTRA-RELATED	coord: 36..216
IPR009003	Peptidase S1, PA clan	SUPERFAMILY	SSF50494	Trypsin-like serine proteases	coord: 78..202

Main menu

SMED30001431

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 1

Owlery

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