SMG-1

Overview
NameSMG-1 (AFH08796.1)
Smed IDSMED30001428
Length (bp)11368
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMG-1 (SMED30001428) t-SNE clustered cells

Violin plots show distribution of expression levels for SMG-1 (SMED30001428) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMG-1 (SMED30001428) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMG-1 (SMED30001428) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001428

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30001428h1SMcG0003511 dd_Smed_v4_4600_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30001428h1SMcG0003511 dd_Smed_v4_4600_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30001428h1SMcG0003511 dd_Smed_v4_4600_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001428h1SMcG0003511 dd_Smed_v4_4600_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
whole organismSMED30001428h1SMcG0003511 JF894292smed_ncbi_20240424PMID:22479207
González-Estévez et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30001428h1SMcG0003511 JF894292smed_ncbi_20240424PMID:22479207
González-Estévez et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of SMG-1 vs. Ensembl Human
Match: SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045])

HSP 1 Score: 482.641 bits (1241), Expect = 1.348e-135
Identity = 360/1173 (30.69%), Postives = 577/1173 (49.19%), Query Frame = 3 
Query: 4395 KWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIER--------ELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLN-TKSLLTLFMWLCNEKSKFPK-------------FCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL--ATKLENQGFSSETICNIEL-----LLKSNFC-PSQMK--------TESDWFGDCYEDSGFLVELRQSILALD--PEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-----------------------------------------ENMNNSSP--------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            K+ R   N +    L++      LGK    Q  + + +    Q Q++         E  KLL+   +   ++++L+S          + S   S K +    KS+LTL  W+  E  +                F   + +S N+  LIEL   P +N +    P+  S E T    V +   +  QL  L+S    +    KS+ ALA W     R + +     E + L    K E Q    +TI   E      +L    C P+ ++        TES+   D  ED    V  RQ I +     E+     E V+K+W + V   FSL+  +  AYF+FLK        D    +   S   +  T      A LR+L L+ K +  LR  + + ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   LI+YP +VG+IS                                         ++ N   P              Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE  ++ T    ETP E WF + + + I + +E++K+P N  +   +W   K   E++L+       ++ +  +     L+L+++SP LA + ++ I LPG     +  ++ S+   I+ILPTKTKPKK  FL ++GK Y YL+KGLEDL LDER+MQ L I NTMF+ IN  E+ ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N   +        RP+++Y+ K+ P L+   + + + SR  WP++++  V  EL   T P+LL+KELW      + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    ++++++    L   L+   S  + + +++    K L+ I++L G E  +      Q  Y       S H +L  Q+R  Q
Sbjct: 1320 KFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSS---------CAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIEL---PSVNTMEEEYPRIES-ESTVHIGVGEPDFILGQLYHLSSVQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITESE---DNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPH---LILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFK---EIMLS-------LQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPGIVP-------RPSELYYSKIGPALKTVGLSLDV-SRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRY-------SEHTQLQTQQRAVQ 2440

HSP 2 Score: 79.7221 bits (195), Expect = 1.461e-13
Identity = 47/148 (31.76%), Postives = 73/148 (49.32%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL     +  T S S       E+E  I++   A  +L   E + G++  S    G    WI ++A +  GR E A  +++E++
Sbjct:  880 LEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLT----EMKTTSLSQGN----ELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHL 1019
[Close]
BLAST of SMG-1 vs. Ensembl Human
Match: SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045])

HSP 1 Score: 482.641 bits (1241), Expect = 1.422e-135
Identity = 360/1173 (30.69%), Postives = 577/1173 (49.19%), Query Frame = 3 
Query: 4395 KWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIER--------ELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLN-TKSLLTLFMWLCNEKSKFPK-------------FCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL--ATKLENQGFSSETICNIEL-----LLKSNFC-PSQMK--------TESDWFGDCYEDSGFLVELRQSILALD--PEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-----------------------------------------ENMNNSSP--------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            K+ R   N +    L++      LGK    Q  + + +    Q Q++         E  KLL+   +   ++++L+S          + S   S K +    KS+LTL  W+  E  +                F   + +S N+  LIEL   P +N +    P+  S E T    V +   +  QL  L+S    +    KS+ ALA W     R + +     E + L    K E Q    +TI   E      +L    C P+ ++        TES+   D  ED    V  RQ I +     E+     E V+K+W + V   FSL+  +  AYF+FLK        D    +   S   +  T      A LR+L L+ K +  LR  + + ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   LI+YP +VG+IS                                         ++ N   P              Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE  ++ T    ETP E WF + + + I + +E++K+P N  +   +W   K   E++L+       ++ +  +     L+L+++SP LA + ++ I LPG     +  ++ S+   I+ILPTKTKPKK  FL ++GK Y YL+KGLEDL LDER+MQ L I NTMF+ IN  E+ ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N   +        RP+++Y+ K+ P L+   + + + SR  WP++++  V  EL   T P+LL+KELW      + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    ++++++    L   L+   S  + + +++    K L+ I++L G E  +      Q  Y       S H +L  Q+R  Q
Sbjct: 1430 KFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSS---------CAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIEL---PSVNTMEEEYPRIES-ESTVHIGVGEPDFILGQLYHLSSVQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITESE---DNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPH---LILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFK---EIMLS-------LQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPGIVP-------RPSELYYSKIGPALKTVGLSLDV-SRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRY-------SEHTQLQTQQRAVQ 2550

HSP 2 Score: 79.7221 bits (195), Expect = 1.649e-13
Identity = 47/148 (31.76%), Postives = 73/148 (49.32%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL     +  T S S       E+E  I++   A  +L   E + G++  S    G    WI ++A +  GR E A  +++E++
Sbjct:  990 LEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLT----EMKTTSLSQGN----ELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHL 1129
[Close]
BLAST of SMG-1 vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882])

HSP 1 Score: 158.688 bits (400), Expect = 1.947e-37
Identity = 102/373 (27.35%), Postives = 175/373 (46.92%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINL-NNFQSVFIT 7298
            P PG +   +   D  + IL +  KPKK     ++GK Y  + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V     L  +  +            + + C      ++ +S  +SE+        ++ + L P+                       +F+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG + +VPE VPFRLT  + N  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++ GH       K  +N +  ++++++   ++++    Q V  T
Sbjct: 2285 PFPG-HWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC------MLPKSAALSEK------LKVFREFLLPRHPP--------------------IFHEWFLRTFPD------------PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVK-GH------SKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKT 2605
[Close]
BLAST of SMG-1 vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882])

HSP 1 Score: 158.303 bits (399), Expect = 2.188e-37
Identity = 102/373 (27.35%), Postives = 175/373 (46.92%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINL-NNFQSVFIT 7298
            P PG +   +   D  + IL +  KPKK     ++GK Y  + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V     L  +  +            + + C      ++ +S  +SE+        ++ + L P+                       +F+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG + +VPE VPFRLT  + N  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++ GH       K  +N +  ++++++   ++++    Q V  T
Sbjct: 2221 PFPG-HWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC------MLPKSAALSEK------LKVFREFLLPRHPP--------------------IFHEWFLRTFPD------------PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVK-GH------SKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKT 2541
[Close]
BLAST of SMG-1 vs. Ensembl Human
Match: ATR (ATR serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:882])

HSP 1 Score: 157.532 bits (397), Expect = 3.889e-37
Identity = 97/334 (29.04%), Postives = 158/334 (47.31%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGH 7184
            P PG +   +   D  + IL +  KPKK     ++GK Y  + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V     L  +  +            + + C      ++ +S  +SE+        ++ + L P+                       +F+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG + +VPE VPFRLT  + N  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++ GH
Sbjct: 1882 PFPG-HWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC------MLPKSAALSEK------LKVFREFLLPRHPP--------------------IFHEWFLRTFPD------------PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKPVK-GH 2169
[Close]
BLAST of SMG-1 vs. Ensembl Celegans
Match: smg-1 (Serine/threonine-protein kinase smg-1 [Source:UniProtKB/Swiss-Prot;Acc:O01510])

HSP 1 Score: 340.502 bits (872), Expect = 4.029e-93
Identity = 238/784 (30.36%), Postives = 392/784 (50.00%), Query Frame = 3 
Query: 5226 IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTT-ANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNS--------------SPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK---HKDVILKLKYNSIIQAAVF-ILERTKNATNM-IPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK------SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMF--SKINEHES-NKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDS-REKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYG-------SFDGGKYAVNSSKSLIDKRSVEFI-INLNNFQSVFITIEDDL----KSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLR 7451
            IW     H       A  +YF F+++ +          K +TT A LRIL L+ K    L D I + +  +    W  ++PQLFARL H  + IR  + +L+ ++  ++ +    +++  + G+ S + +                +    ++  + ++   LV++V  F+ EL RI +L +E W   +G    E+ K+   +++E  K +S   L      D+I+K     ++   +F +L+     T +  P++  E  F   FAE +T+  +E +          +W   K L    +  ++       K+G   F   + +D+SP LA +++S +P+PG  +       S+  + + ++ILPTKT+PKK  F+ ++GK  ++L+KG EDL LDERVMQ L + N M    K    +S   Y    Y V PLG R+GLI+ VE AT +F +Y++ QM+ K        K     NG+ V E           RP+++Y   +R      KID  I S R KWP  IL EVF  L   T  DL+S+ELW  + ++  W+  +  ++RS AVM ++G  LGLGDRHLDNLLV+   G ++HIDYN+CFDKG +L++PE VPFRLT  + +  GP  + G FR SC +V   ++     +  L+D F+FDP+VDW+S   +   G       +  G  +   + + L D  ++E + + ++  Q++++   DDL    K   E L+++   L  +   +    K   E++ A  +   + + LR
Sbjct: 1413 IWKMVRDHRTKFLSIAVTSYFQFIQNMSGDCDNLPYSKKEETTLATLRILELLVKHGDVLIDVINDGLNKTNVHIWKEILPQLFARLSHPSEHIRKTLVDLISKICTAAPHA---VVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCEKLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIVK--RTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSP-EKSWIPFKNLIANFVHRNS-------KKGMQTF---ETEDISPYLASLSNSCVPMPGQESVEFDRVVSISRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKAL------KQATKKNGETVPEIE---------RPSNMYHNMIRLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGKNLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHEHTATSGVSLALQLAVYGSNWKTKAKERLTD--AMELLNLRMSEVQTLWLANRDDLLHWMKQVTECLLIENSMLGANAIYAQQRVKAGTELREAVTRHHALAKELR 2163
[Close]
BLAST of SMG-1 vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95])

HSP 1 Score: 191.815 bits (486), Expect = 6.356e-48
Identity = 148/581 (25.47%), Postives = 259/581 (44.58%), Query Frame = 3 
Query: 5436 PPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKG-VSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            P  +W   IPQL ARL   D   +  +  +L+ L   + +  + +IY   V S S++++ S     + + ++E + +LV E  +  +EL R  +LW E W  +L      +    + +Q+  D + + +DL  K     +K +S  Q     L+                                 +S  N+++ N AW            E   ++  KL+       SL L  VSP L       + +PG  + S     + S    ++++ +K +P+K     +NG  Y +L KG ED R DERVMQ+ G+ NT+ +  +E       I  Y +  L   +GLI  V    +L +L K ++ +        K+K   S     + + ++ +E            QKL+    A  +  G D R                           LW  S +S  W+    N+TRS A M ++G+ LGLGDRH  NL+++   G+++HID+  CF+   +  K PE+VPFRLT ++ N      ++G++  + E V ++++ +Q+S+L +++ F++DP+++W
Sbjct: 2103 PVTTWLEAIPQLMARLDCPDD--QKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDA-SRVYFHDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAF------------------------ESSGNVKDLNQAW------------EIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREK--------KAKIPLSIEHKTLQKLSLETEHL-------TLMQKLQLFESALSVTQGEDLRHV-------------------------LWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINW 2604
[Close]
BLAST of SMG-1 vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95])

HSP 1 Score: 191.815 bits (486), Expect = 6.515e-48
Identity = 148/581 (25.47%), Postives = 259/581 (44.58%), Query Frame = 3 
Query: 5436 PPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKG-VSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            P  +W   IPQL ARL   D   +  +  +L+ L   + +  + +IY   V S S++++ S     + + ++E + +LV E  +  +EL R  +LW E W  +L      +    + +Q+  D + + +DL  K     +K +S  Q     L+                                 +S  N+++ N AW            E   ++  KL+       SL L  VSP L       + +PG  + S     + S    ++++ +K +P+K     +NG  Y +L KG ED R DERVMQ+ G+ NT+ +  +E       I  Y +  L   +GLI  V    +L +L K ++ +        K+K   S     + + ++ +E            QKL+    A  +  G D R                           LW  S +S  W+    N+TRS A M ++G+ LGLGDRH  NL+++   G+++HID+  CF+   +  K PE+VPFRLT ++ N      ++G++  + E V ++++ +Q+S+L +++ F++DP+++W
Sbjct: 2100 PVTTWLEAIPQLMARLDCPDD--QKSVQLVLRVLCEIARHRPQAVIYALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDA-SRVYFHDNNVQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYVQAF------------------------ESSGNVKDLNQAW------------EIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDPSAPIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREK--------KAKIPLSIEHKTLQKLSLETEHL-------TLMQKLQLFESALSVTQGEDLRHV-------------------------LWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINW 2601
[Close]
BLAST of SMG-1 vs. Ensembl Celegans
Match: smg-1 (Serine/threonine-protein kinase smg-1 [Source:UniProtKB/Swiss-Prot;Acc:O01510])

HSP 1 Score: 163.696 bits (413), Expect = 1.962e-39
Identity = 132/461 (28.63%), Postives = 225/461 (48.81%), Query Frame = 3 
Query: 5226 IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTT-ANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNS----SPYHDIKKV----------LVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK---HKDVILKLKYNSIIQAAVF-ILERTKNATNM-IPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK------SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMF--SKINEHES-NKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMR 6521
            IW     H       A  +YF F+++ +          K +TT A LRIL L+ K    L D I + +  +    W  ++PQLFARL H  + IR  + +L+ ++  ++ +    +++  + G+ S + +          D  +V          + ++   LV++V  F+ EL RI +L +E W   +G    E+ K+   +++E  K +S   L      D+I+K     ++   +F +L+     T +  P++  E  F   FAE +T+  +E +          +W   K L    +  ++       K+G   F   + +D+SP LA +++S +P+PG  +       S+  + + ++ILPTKT+PKK  F+ ++GK  ++L+KG EDL LDERVMQ L + N M    K    +S   Y    Y V PLG R+GLI+ VE AT +F +Y++ QM+
Sbjct: 1413 IWKMVRDHRTKFLSIAVTSYFQFIQNMSGDCDNLPYSKKEETTLATLRILELLVKHGDVLIDVINDGLNKTNVHIWKEILPQLFARLSHPSEHIRKTLVDLISKICTAAPHA---VVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCEKLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIVK--RTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSP-EKSWIPFKNLIANFVHRNS-------KKGMQTF---ETEDISPYLASLSNSCVPMPGQESVEFDRVVSISRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMK 1857
[Close]
BLAST of SMG-1 vs. Ensembl Celegans
Match: atl-1 (Serine/threonine-protein kinase ATR [Source:UniProtKB/Swiss-Prot;Acc:Q22258])

HSP 1 Score: 119.398 bits (298), Expect = 2.996e-26
Identity = 79/292 (27.05%), Postives = 134/292 (45.89%), Query Frame = 3 
Query: 6231 ISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLF-SLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQK-LRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQ 7100
            + +L + TKP   +  +  G+    + K  +DL  D    +++ + N +  K  +    K   TTY V PLG + G+I+ +E  TS + +L K   M +    + LK                              +W   ++P        +G + R K+        F E+    +P ++ K        +  W+ S   F +S AVM ++G+  GLGDRH  NL+V+ + G+ IH+D+++ F+KG +L  PE VPFRLT  + N  G +A++G FR  CE    + ++
Sbjct:  722 VKVLHSNTKPVIIKLTTKTGRIVRLICKKDDDLSKDYHFTKMVEMCNDLLMKDEQTRIQKMTATTYSVIPLGKQGGIIEFMEGVTSFYETLDKLMGMTSGEWLEKLK------------------------------FWNTHMKP--------MGKEERTKY--------FREVACKNTPVVMGKWFRIQYPEAGQWFASRKLFAKSTAVMSVIGYIFGLGDRHTKNLMVH-TTGKCIHVDFDMIFNKGETLGTPELVPFRLTQNMINGMGEVALDGEFRTVCEQALRVFRE 966
[Close]
BLAST of SMG-1 vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0070972)

HSP 1 Score: 392.119 bits (1006), Expect = 1.447e-108
Identity = 224/691 (32.42%), Postives = 373/691 (53.98%), Query Frame = 3 
Query: 5196 TSQMAEEVVKIWLEFVTHHFSLHIAAAEAYF---SFLKDATPTKA----------KYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSP-------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-------LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNK-YHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSS 7166
            T +  + +++IW   + + +  +  AA +YF   SF   + P K           +  + + N  T  LR+L LI K +  L++ +   + T+P   W  +IPQLF+RL H +  +R  + +LL RLA S     +L+I+P +VG+  E  + ++P             Y  +   L +   + V+ V + +KELRR+ +LWDE W+ SL   Y+    +   L ++       DD + K+     ++N      +  LE     T+  PET  E  F   F   I  T++ ++     R + +AW K+K L  ++  +SN      + RG     +LK+  +SP L  I    I +PG++          + S++  + +LPTKTKPKK  F  +NG+ Y++L+KG+EDL LDER+MQ L I+N + +  ++   N  Y    Y V PLG ++GLI  V+  T +F+LYK+ Q R                       +   +    P R TD+++ KL P L    + +  D R +WP+++L++V +EL+++T  DLL++ELWC + N+  W +S   F R  +VM ++G+ +GLGDRHLDN+L+N  +G ++HIDYNVCF+KG +L++PEKVPFRLT  +    G   + G FR+ CE V +++++ ++++LTL++ F++DP+VDW++
Sbjct: 1548 TPEALDAILQIWRRAIANTYDYYKDAARSYFQYLSFKSGSGPEKPEGEGVVSQRERLHVDDSNLVTTTLRLLRLIVKHASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLAKSR---PQLVIFPAVVGANREQQDATAPPATARPTTEDACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRP----DDHEGKNN----RFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVDALRH----RRYPEAWDKLKQLYHIL--QSN------MIRGSGS--TLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQV----------------AGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVS-DPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTT 2196

HSP 2 Score: 66.6254 bits (161), Expect = 7.045e-10
Identity = 48/200 (24.00%), Postives = 86/200 (43.00%), Query Frame = 3 
Query: 3267 VNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLL 3866
            ++L++  LD LEK+ YN  EG      P  K +  FF  N   C  WF ++R+ +V +A +  Q   VI +  Q+L              +K   P     IV  + +       ++L GL   +       + W++  AD+  G+ E AL+ +   +         +L SE+   TR+    S  + C++++    +L+
Sbjct:  919 LSLLLGFLDALEKLIYNAAEGSAFALRPPEKQVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQPELVIRYAQQIL------------VNSKTQDPTYSQAIVYMAWSLVSCQEADSLRGLRLWARGKSCKSYKWLKYAADQAAGKRESALAGYRTILAEK------ELQSELEPHTRQFVV-SQMMQCLQDLGQWSQLV 1099
[Close]
BLAST of SMG-1 vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0343321)

HSP 1 Score: 392.119 bits (1006), Expect = 1.447e-108
Identity = 224/691 (32.42%), Postives = 373/691 (53.98%), Query Frame = 3 
Query: 5196 TSQMAEEVVKIWLEFVTHHFSLHIAAAEAYF---SFLKDATPTKA----------KYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSP-------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-------LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNK-YHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSS 7166
            T +  + +++IW   + + +  +  AA +YF   SF   + P K           +  + + N  T  LR+L LI K +  L++ +   + T+P   W  +IPQLF+RL H +  +R  + +LL RLA S     +L+I+P +VG+  E  + ++P             Y  +   L +   + V+ V + +KELRR+ +LWDE W+ SL   Y+    +   L ++       DD + K+     ++N      +  LE     T+  PET  E  F   F   I  T++ ++     R + +AW K+K L  ++  +SN      + RG     +LK+  +SP L  I    I +PG++          + S++  + +LPTKTKPKK  F  +NG+ Y++L+KG+EDL LDER+MQ L I+N + +  ++   N  Y    Y V PLG ++GLI  V+  T +F+LYK+ Q R                       +   +    P R TD+++ KL P L    + +  D R +WP+++L++V +EL+++T  DLL++ELWC + N+  W +S   F R  +VM ++G+ +GLGDRHLDN+L+N  +G ++HIDYNVCF+KG +L++PEKVPFRLT  +    G   + G FR+ CE V +++++ ++++LTL++ F++DP+VDW++
Sbjct: 1548 TPEALDAILQIWRRAIANTYDYYKDAARSYFQYLSFKSGSGPEKPEGEGVVSQRERLHVDDSNLVTTTLRLLRLIVKHASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLAKSR---PQLVIFPAVVGANREQQDATAPPATARPTTEDACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRP----DDHEGKNN----RFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVDALRH----RRYPEAWDKLKQLYHIL--QSN------MIRGSGS--TLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQV----------------AGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVS-DPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTT 2196

HSP 2 Score: 66.6254 bits (161), Expect = 7.045e-10
Identity = 48/200 (24.00%), Postives = 86/200 (43.00%), Query Frame = 3 
Query: 3267 VNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLL 3866
            ++L++  LD LEK+ YN  EG      P  K +  FF  N   C  WF ++R+ +V +A +  Q   VI +  Q+L              +K   P     IV  + +       ++L GL   +       + W++  AD+  G+ E AL+ +   +         +L SE+   TR+    S  + C++++    +L+
Sbjct:  919 LSLLLGFLDALEKLIYNAAEGSAFALRPPEKQVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQPELVIRYAQQIL------------VNSKTQDPTYSQAIVYMAWSLVSCQEADSLRGLRLWARGKSCKSYKWLKYAADQAAGKRESALAGYRTILAEK------ELQSELEPHTRQFVV-SQMMQCLQDLGQWSQLV 1099
[Close]
BLAST of SMG-1 vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0080422)

HSP 1 Score: 207.608 bits (527), Expect = 1.354e-52
Identity = 163/623 (26.16%), Postives = 285/623 (45.75%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSL---IGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXX---XXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            SL   N     LR+L+L    G  +  + +++++ +K     +W  VIPQL AR+    +++   + +LL  +     N  + ++YP  V S S ++   +    I   + +++  LVE+  +  +EL R+ +LW E W   L                     +    L   D  +K  +  I++    +LER        P+T +E+ F   +  E+T      +  K+   + + + AW            +   ++  K+ R   Q  SL+L  VSP L       + +PG  N       +  I  ++ ++ +K +P+K     +NGK Y YL KG EDLR DERVMQ+  + NT+     +       I  Y V PL T +GLI  V    +L +L + ++ + K   +                                   Q+ R  L  A     +   +K      +EVF      T  D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++  +G+++HID+  CF+  ++  K PEK+PFRLT ++        + G +R +CE+V  ++++++DS++ +++ F++DP+++W
Sbjct: 1814 SLIKGNSLQDTLRLLTLWFDYGNHA-EVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIG---KNHPQALVYPLTVASKSASLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGL---------------------EEASRLYFGDRNVKGMFE-ILEPLHAMLERG-------PQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAW------------DIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLN-----------------------------------QEHRTMLNFAPDYDHLTLMQK------VEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW 2350
[Close]
BLAST of SMG-1 vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0336615)

HSP 1 Score: 207.608 bits (527), Expect = 1.355e-52
Identity = 163/623 (26.16%), Postives = 285/623 (45.75%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSL---IGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXX---XXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            SL   N     LR+L+L    G  +  + +++++ +K     +W  VIPQL AR+    +++   + +LL  +     N  + ++YP  V S S ++   +    I   + +++  LVE+  +  +EL R+ +LW E W   L                     +    L   D  +K  +  I++    +LER        P+T +E+ F   +  E+T      +  K+   + + + AW            +   ++  K+ R   Q  SL+L  VSP L       + +PG  N       +  I  ++ ++ +K +P+K     +NGK Y YL KG EDLR DERVMQ+  + NT+     +       I  Y V PL T +GLI  V    +L +L + ++ + K   +                                   Q+ R  L  A     +   +K      +EVF      T  D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++  +G+++HID+  CF+  ++  K PEK+PFRLT ++        + G +R +CE+V  ++++++DS++ +++ F++DP+++W
Sbjct: 1815 SLIKGNSLQDTLRLLTLWFDYGNHA-EVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQLVGQLIHQLLMDIG---KNHPQALVYPLTVASKSASLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGL---------------------EEASRLYFGDRNVKGMFE-ILEPLHAMLERG-------PQTLKETSFSQAYGRELTEAYEWSQRYKTSAVVMDLDRAW------------DIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNPGQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKKKVPLN-----------------------------------QEHRTMLNFAPDYDHLTLMQK------VEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW 2351
[Close]
BLAST of SMG-1 vs. Ensembl Fly
Match: mei-41 (gene:FBgn0004367 transcript:FBtr0074271)

HSP 1 Score: 128.257 bits (321), Expect = 1.372e-28
Identity = 85/309 (27.51%), Postives = 138/309 (44.66%), Query Frame = 3 
Query: 6231 ISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFS----LYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFD 7145
            + IL +  KPKK     ++GK Y  L K  +DLR D R+M+  G+      +       + HI TY V P     GL++ +    S  S    LY   Q R   +   L+S A   +   I  +  + +++  P  P  ++ + LR                               R  +P              ++WY +   + R+ AVM ++G+ LGLGDRH +N+L    NG  +H+D+N  F++G  L  PE VPFRLT  +    GP+ V G FR  CE    +++Q   ++++++  F++D
Sbjct: 2188 VLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLHQDAPARQRRLHIRTYAVLPFNEECGLVEWLPNLASYRSICMNLYA--QRRLVMSTRQLQSLAVPLHES-IERKREVFTKQLVPAHPP-VFQEWLR------------------------------QRFATP--------------HSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGELLPYPEVVPFRLTHNMIVAMGPLGVEGSFRKCCEITLRLLKQESKTLMSILRPFVYD 2448
[Close]
BLAST of SMG-1 vs. Ensembl Zebrafish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767])

HSP 1 Score: 487.649 bits (1254), Expect = 2.415e-137
Identity = 350/1150 (30.43%), Postives = 581/1150 (50.52%), Query Frame = 3 
Query: 4527 QIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNT-KSLLTLFMWLCNE-KSKFPKFCNDAK----------ISSNLQFLIELAEVPWIN-GLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL-------ATKLENQGFSSETICNIELLLKSNFC-PSQMKTESDWFGDCYEDSGFLVE-LRQSILALDP---EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK---DATPTK---AKYSLCNKNK--------TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-------------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK--HKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKI---VEQFNYVRKLEERSMHLELDIQKRQQQL-KLVSMEHSAFFNKILSAADFISLKLDIKN 7652
            ++E E  K+L+   +   ++++L+S          + S  HS KC+L   +S+LTL  WL  + K   P+     K          +S N+  L+EL   P  + G+P     H + E T    V +   V  QL  L++    +    KS+ ALA W     R + +     E + L         +L   G S E    I  +L    C P+ ++ E     +  +D   +V+ + + +L   P   ++   + + ++ +W   V   FSL+  +  AYF+FLK      P      K  L N+N           A LR+L L+ K +  LR+ + + + ++P   W  +IPQLF+RL H +  IR  +  LL R+A  S +   LI+YP +VGSIS                               E+   S P                         Y  I   L   N  +V +V + + ELRR+T+LWDELW+  L Q +  + ++  QL+ E+ ++ + + L+   K  I++ K++++++  VF L+  ++ T    ETP E WF   + + I + +E ++SP N      +W   K   +++L+      K      R  +L L+LD++SP L  + ++ + LPG     +  ++ S+   I+ILPTKTKPKK  FL ++G++Y YL+KGLEDL LDER+MQ L I NTMF+K+N+ ES ++    Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       ++++    +     N   +        RP+++Y+ K+ P L+A  + + + SR  WP++++ +V  EL   T P+LL+KELWC     + W+  +  + RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V +I+++ ++++LTL++ F++DP+VDW++G E G  G+  GG      +K    KR +E  I  + F S    I+ +    ++++      L E ++   +  + + +++    K L+ +++L G +T  +  I     +++   +L+ R   ++  IQ +   L + +S   +AF N  L A    SL  +I +
Sbjct: 1470 ELEIEKAKVLFAAGQSVSAMEMLSS---------CALSYCHSGKCELAACRSVLTLCKWLLADWKDLTPQLKMVVKKNSGSTSLSTLSKNISGLLEL---PLEDQGMP-----HITTETTVSVGVGEPDFVLGQLYQLSTTQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPAGTSDEDKETIFGILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIGRQLLGACPWLSDVEDTVTDGLIGVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPH---LILYPAIVGSISLGGEAQAAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHEEWFQETYGDAIHNALERLRSPLNPANPASSWVPFK---QIMLSLQQRAQK------RASYL-LRLDEISPRLTAMANTEMALPGEVSATDAVTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAV----VQAQKAQDSFQQPQNLPMV-------PRPSELYYSKISPALKAVGLSLDV-SRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQ--SKREMERDITRSLFSSRVAEIKVNWFKNRDEMTGVLPQLEEAVDEYLNLQEQLTQVEKVQGKLLEELEFLEGGDTRADHPIHSLEHRYSEHTQLQSRQRTVQDAIQGKLSDLDQWISQYQAAFAN--LEATQLASLLQEISS 2571

HSP 2 Score: 81.6481 bits (200), Expect = 2.243e-14
Identity = 56/201 (27.86%), Postives = 96/201 (47.76%), Query Frame = 3 
Query: 3132 TLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEE 3734
            T  TIE M++S+    +SL   T++   +     + +      L + L++  L+ LEK+ YN YEGC        K I TFF TN+  C +W  ++RL ++ +   SGQ +  + HG  LL   +   +T          PE+E  + +   A  +L   E + GL+  S+   G    W+ ++A +  G+ E A  +++E
Sbjct:  934 TFQTIEGMIRSL--AAHSLN--TEQELSQWSGGESDEGHHTNQLRLALLLQFLENLEKLMYNAYEGCASALTAPPKGIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFDLLT-EIKNSSTQG--------PEMEVPVTMLVEALCELRCPEAIQGLAAWSLANTGKSMGWLSSVALQAEGKFEKAALEYQE 1121
[Close]
BLAST of SMG-1 vs. Ensembl Zebrafish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767])

HSP 1 Score: 485.723 bits (1249), Expect = 9.499e-137
Identity = 343/1117 (30.71%), Postives = 566/1117 (50.67%), Query Frame = 3 
Query: 4527 QIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNT-KSLLTLFMWLCNE-KSKFPKFCNDAK----------ISSNLQFLIELAEVPWIN-GLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL-------ATKLENQGFSSETICNIELLLKSNFC-PSQMKTESDWFGDCYEDSGFLVE-LRQSILALDP---EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK---DATPTK---AKYSLCNKNK--------TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-------------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK--HKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEER-SMHLELDIQKRQQQ 7562
            ++E E  K+L+   +   ++++L+S          + S  HS KC+L   +S+LTL  WL  + K   P+     K          +S N+  L+EL   P  + G+P     H + E T    V +   V  QL  L++    +    KS+ ALA W     R + +     E + L         +L   G S E    I  +L    C P+ ++ E     +  +D   +V+ + + +L   P   ++   + + ++ +W   V   FSL+  +  AYF+FLK      P      K  L N+N           A LR+L L+ K +  LR+ + + + ++P   W  +IPQLF+RL H +  IR  +  LL R+A  S +   LI+YP +VGSIS                               E+   S P                         Y  I   L   N  +V +V + + ELRR+T+LWDELW+  L Q +  + ++  QL+ E+ ++ + + L+   K  I++ K++++++  VF L+  ++ T    ETP E WF   + + I + +E ++SP N      +W   K   +++L+      K      R  +L L+LD++SP L  + ++ + LPG     +  ++ S+   I+ILPTKTKPKK  FL ++G++Y YL+KGLEDL LDER+MQ L I NTMF+K+N+ ES ++    Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       ++++    +     N   +        RP+++Y+ K+ P L+A  + + + SR  WP++++ +V  EL   T P+LL+KELWC     + W+  +  + RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V +I+++ ++++LTL++ F++DP+VDW++G E G  G+  GG      +K    KR +E  I  + F S    I+ +    ++++      L E ++   +  + + +++    K L+ +++L G +T  +       + +  LE R S H +L  ++R  Q
Sbjct: 1461 ELEIEKAKVLFAAGQSVSAMEMLSS---------CALSYCHSGKCELAACRSVLTLCKWLLADWKDLTPQLKMVVKKNSGSTSLSTLSKNISGLLEL---PLEDQGMP-----HITTETTVSVGVGEPDFVLGQLYQLSTTQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPAGTSDEDKETIFGILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIGRQLLGACPWLSDVEDTVTDGLIGVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPH---LILYPAIVGSISLGGEAQTAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHEEWFQETYGDAIHNALERLRSPLNPANPASSWVPFK---QIMLSLQQRAQK------RASYL-LRLDEISPRLTAMANTEMALPGEVSATDAVTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAV----VQAQKAQDSFQQPQNLPMV-------PRPSELYYSKISPALKAVGLSLDV-SRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQ--SKREMERDITRSLFSSRVAEIKVNWFKNRDEMTGVLPQLEEAVDEYLNLQEQLTQVEKVQGKLLEELEFLEGADTRAD-------HPIHSLEHRYSEHTQLQSRQRTVQ 2524

HSP 2 Score: 81.6481 bits (200), Expect = 2.419e-14
Identity = 44/146 (30.14%), Postives = 71/146 (48.63%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEE 3734
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL ++ +   SGQ +  + HG  LL   +   +T          PE+E  + +   A  +L   E + GL+  S+   G    W+ ++A +  G+ E A  +++E
Sbjct:  981 LEKLMYNAYEGCASALTAPPKGIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFDLLT-EIKNSSTQG--------PEMEVPVTMLVEALCELRCPEAIQGLAAWSLANTGKSMGWLSSVALQAEGKFEKAALEYQE 1117
[Close]
BLAST of SMG-1 vs. Ensembl Zebrafish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767])

HSP 1 Score: 485.337 bits (1248), Expect = 1.195e-136
Identity = 343/1117 (30.71%), Postives = 566/1117 (50.67%), Query Frame = 3 
Query: 4527 QIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNT-KSLLTLFMWLCNE-KSKFPKFCNDAK----------ISSNLQFLIELAEVPWIN-GLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL-------ATKLENQGFSSETICNIELLLKSNFC-PSQMKTESDWFGDCYEDSGFLVE-LRQSILALDP---EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK---DATPTK---AKYSLCNKNK--------TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-------------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK--HKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEER-SMHLELDIQKRQQQ 7562
            ++E E  K+L+   +   ++++L+S          + S  HS KC+L   +S+LTL  WL  + K   P+     K          +S N+  L+EL   P  + G+P     H + E T    V +   V  QL  L++    +    KS+ ALA W     R + +     E + L         +L   G S E    I  +L    C P+ ++ E     +  +D   +V+ + + +L   P   ++   + + ++ +W   V   FSL+  +  AYF+FLK      P      K  L N+N           A LR+L L+ K +  LR+ + + + ++P   W  +IPQLF+RL H +  IR  +  LL R+A  S +   LI+YP +VGSIS                               E+   S P                         Y  I   L   N  +V +V + + ELRR+T+LWDELW+  L Q +  + ++  QL+ E+ ++ + + L+   K  I++ K++++++  VF L+  ++ T    ETP E WF   + + I + +E ++SP N      +W   K   +++L+      K      R  +L L+LD++SP L  + ++ + LPG     +  ++ S+   I+ILPTKTKPKK  FL ++G++Y YL+KGLEDL LDER+MQ L I NTMF+K+N+ ES ++    Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       ++++    +     N   +        RP+++Y+ K+ P L+A  + + + SR  WP++++ +V  EL   T P+LL+KELWC     + W+  +  + RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V +I+++ ++++LTL++ F++DP+VDW++G E G  G+  GG      +K    KR +E  I  + F S    I+ +    ++++      L E ++   +  + + +++    K L+ +++L G +T  +       + +  LE R S H +L  ++R  Q
Sbjct: 1466 ELEIEKAKVLFAAGQSVSAMEMLSS---------CALSYCHSGKCELAACRSVLTLCKWLLADWKDLTPQLKMVVKKNSGSTSLSTLSKNISGLLEL---PLEDQGMP-----HITTETTVSVGVGEPDFVLGQLYQLSTTQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPAGTSDEDKETIFGILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIGRQLLGACPWLSDVEDTVTDGLIGVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPH---LILYPAIVGSISLGGEAQTAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHEEWFQETYGDAIHNALERLRSPLNPANPASSWVPFK---QIMLSLQQRAQK------RASYL-LRLDEISPRLTAMANTEMALPGEVSATDAVTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAV----VQAQKAQDSFQQPQNLPMV-------PRPSELYYSKISPALKAVGLSLDV-SRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQ--SKREMERDITRSLFSSRVAEIKVNWFKNRDEMTGVLPQLEEAVDEYLNLQEQLTQVEKVQGKLLEELEFLEGADTRAD-------HPIHSLEHRYSEHTQLQSRQRTVQ 2529

HSP 2 Score: 81.6481 bits (200), Expect = 2.419e-14
Identity = 44/146 (30.14%), Postives = 71/146 (48.63%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEE 3734
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL ++ +   SGQ +  + HG  LL   +   +T          PE+E  + +   A  +L   E + GL+  S+   G    W+ ++A +  G+ E A  +++E
Sbjct:  981 LEKLMYNAYEGCASALTAPPKGIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFDLLT-EIKNSSTQG--------PEMEVPVTMLVEALCELRCPEAIQGLAAWSLANTGKSMGWLSSVALQAEGKFEKAALEYQE 1117
[Close]
BLAST of SMG-1 vs. Ensembl Zebrafish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458])

HSP 1 Score: 155.221 bits (391), Expect = 1.203e-36
Identity = 110/388 (28.35%), Postives = 177/388 (45.62%), Query Frame = 3 
Query: 6156 LAKINSSLIP-LP---GMNNKS---------LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDI---YWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINL 7271
            L  + S LIP LP   G N K          L   D  + IL +  KPKK     ++GK Y+ + K  +DLR D R+M+   + N    K  E       I TY V PL    G+I+ V +   L     RH +                        + +  E+G  +  T++      K  P  E  K+   +      P      VF+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG +  VPE VPFRLT  + +  GPM   GLFR +CE +  +++  ++ +++++  F+ DP+V+WS  ++          K  VN S  ++++++   ++++
Sbjct: 2253 LIPLQSVLIPTLPSTGGANPKHDAFPGHWVYLSGFDDTVEILASLQKPKKISLKGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKSLRKDAESRRRDLRIRTYAVIPLNEECGIIEWVNKTAGL-----RHIL------------------------TKLYKEKGIYVSGTELKKLILPKTAPFQEKLKLHKDVLCARHPP------VFHEWFLRTFPD------------PTSWYNSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVILRLMRDQREPLMSVLKTFLHDPLVEWSKPVKG-------FSKTQVNESGEILNEKAKTHVLDI 2586
[Close]
BLAST of SMG-1 vs. Ensembl Zebrafish
Match: AL844179.1 (pep chromosome:GRCz11:CHR_ALT_CTG8_1_27:46082265:46126761:-1 gene:ENSDARG00000112020.1 transcript:ENSDART00000184694.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844179.1)

HSP 1 Score: 139.043 bits (349), Expect = 2.153e-32
Identity = 58/146 (39.73%), Postives = 101/146 (69.18%), Query Frame = 3 
Query: 6726 IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            +EVF     +T+ D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++  +G+++HID+  CF+  ++  K PEK+PFRLT ++TN      ++G +RI+C  V E++++ +DS++ +++ F++DP+++W
Sbjct:  472 VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNW 617

HSP 2 Score: 113.62 bits (283), Expect = 2.116e-24
Identity = 99/414 (23.91%), Postives = 178/414 (43.00%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSLIGKRSR--SLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQC----YDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKS---PNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGM--NNKSLL---SIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNK 6527
            SL   N     LR+L+L         + ++++  IKT    +W  VIPQL AR+     ++   + +LL  +        + +IYP  V S S      +  + I K + E+   LV++  +  +EL R+ +LW E+W   L +     + E N K                             ++++    ++ER        P+T +E+ F+  +  ++    +  +      N+++   AW                ++  ++ +   Q  SL+L  VSP L       + +PG    N+S++   SI   + ++ +K +P+K   + +NG  + +L KG EDLR DERVMQ+ G+ NT+ +           I  Y V PL T +GLI  V    +L +L + ++ + K
Sbjct:   81 SLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIG---RYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKG--------------------------MFAVLEPLHAMMERG-------PQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAWDLYY------------HVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKK 446
[Close]
BLAST of SMG-1 vs. Ensembl Xenopus
Match: SMG1 (SMG1 phosphatidylinositol 3-kinase-related kinase [Source:NCBI gene;Acc:100145499])

HSP 1 Score: 478.404 bits (1230), Expect = 2.350e-134
Identity = 290/864 (33.56%), Postives = 469/864 (54.28%), Query Frame = 3 
Query: 5190 EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-----------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            ++  + +E ++K+W + V   FSL+  +  AYF+FLK        D    +   ++ +K  T      A LR+L L+ K +  LR  +   ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A   ++   LI+YP +VGSIS                               E    S P                       Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE   + T+   ETP E WF + + E I + +E++++P+N     ++W   K   +++L+      K      R  +L L+L+++SP L  + ++ I LPG     +  ++ S+  +I+ILPTKTKPKKF FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+ IN  ES  +H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N + +        RP+++Y+ K+ P L+A  + + + SR  WP+N++  V  EL   T P+LL+KELWC   + + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    +E+++     L   L    +  + + +++    K ++ +++L G E+        Q  +       S H +L  Q+R  Q
Sbjct: 1713 DLEEKASEGLIKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGRVSLDEDDPRLHLNIPSKQSTDDVIVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA---HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDELKNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYGEAIGNALEKLRNPSNPANPGNSWMPFK---QIMLSLQQRAQK------RASYL-LRLEEISPCLTAMTNTEIALPGEVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINSKESPHFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPAMVP-------RPSELYYSKISPALKAVGLSLDV-SRRDWPLNVMKSVLEELMEATPPNLLAKELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITQSLFSSRVAEIKVNWFKNKEEMLSVLPKLDTSLEEYLNLHEELMDVEKLQTKLMEEMEFLEGAESTEHPSHTLQHRF-------SEHTQLQTQQRAVQ 2542

HSP 2 Score: 79.337 bits (194), Expect = 1.970e-13
Identity = 45/148 (30.41%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            L+K+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL   +   NT   +       E E  +++   A  +L   E + GL+  S    G    WI ++A    GR E A  +++E++
Sbjct:  984 LDKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLT-EMKNNNTPQGT-------EFELTVMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHL 1123
[Close]
BLAST of SMG-1 vs. Ensembl Xenopus
Match: SMG1 (SMG1 phosphatidylinositol 3-kinase-related kinase [Source:NCBI gene;Acc:100145499])

HSP 1 Score: 477.633 bits (1228), Expect = 4.220e-134
Identity = 290/864 (33.56%), Postives = 469/864 (54.28%), Query Frame = 3 
Query: 5190 EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-----------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            ++  + +E ++K+W + V   FSL+  +  AYF+FLK        D    +   ++ +K  T      A LR+L L+ K +  LR  +   ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A   ++   LI+YP +VGSIS                               E    S P                       Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE   + T+   ETP E WF + + E I + +E++++P+N     ++W   K   +++L+      K      R  +L L+L+++SP L  + ++ I LPG     +  ++ S+  +I+ILPTKTKPKKF FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+ IN  ES  +H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N + +        RP+++Y+ K+ P L+A  + + + SR  WP+N++  V  EL   T P+LL+KELWC   + + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    +E+++     L   L    +  + + +++    K ++ +++L G E+        Q  +       S H +L  Q+R  Q
Sbjct: 1703 DLEEKASEGLIKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGRVSLDEDDPRLHLNIPSKQSTDDVIVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA---HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDELKNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYGEAIGNALEKLRNPSNPANPGNSWMPFK---QIMLSLQQRAQK------RASYL-LRLEEISPCLTAMTNTEIALPGEVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINSKESPHFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPAMVP-------RPSELYYSKISPALKAVGLSLDV-SRRDWPLNVMKSVLEELMEATPPNLLAKELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITQSLFSSRVAEIKVNWFKNKEEMLSVLPKLDTSLEEYLNLHEELMDVEKLQTKLMEEMEFLEGAESTEHPSHTLQHRF-------SEHTQLQTQQRAVQ 2532

HSP 2 Score: 79.337 bits (194), Expect = 1.953e-13
Identity = 45/148 (30.41%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            L+K+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL   +   NT   +       E E  +++   A  +L   E + GL+  S    G    WI ++A    GR E A  +++E++
Sbjct:  974 LDKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLT-EMKNNNTPQGT-------EFELTVMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHL 1113
[Close]
BLAST of SMG-1 vs. Ensembl Xenopus
Match: SMG1 (SMG1 phosphatidylinositol 3-kinase-related kinase [Source:NCBI gene;Acc:100145499])

HSP 1 Score: 477.633 bits (1228), Expect = 4.243e-134
Identity = 290/864 (33.56%), Postives = 469/864 (54.28%), Query Frame = 3 
Query: 5190 EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-----------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            ++  + +E ++K+W + V   FSL+  +  AYF+FLK        D    +   ++ +K  T      A LR+L L+ K +  LR  +   ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A   ++   LI+YP +VGSIS                               E    S P                       Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE   + T+   ETP E WF + + E I + +E++++P+N     ++W   K   +++L+      K      R  +L L+L+++SP L  + ++ I LPG     +  ++ S+  +I+ILPTKTKPKKF FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+ IN  ES  +H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N + +        RP+++Y+ K+ P L+A  + + + SR  WP+N++  V  EL   T P+LL+KELWC   + + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    +E+++     L   L    +  + + +++    K ++ +++L G E+        Q  +       S H +L  Q+R  Q
Sbjct: 1678 DLEEKASEGLIKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGRVSLDEDDPRLHLNIPSKQSTDDVIVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA---HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDELKNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYGEAIGNALEKLRNPSNPANPGNSWMPFK---QIMLSLQQRAQK------RASYL-LRLEEISPCLTAMTNTEIALPGEVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINSKESPHFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPAMVP-------RPSELYYSKISPALKAVGLSLDV-SRRDWPLNVMKSVLEELMEATPPNLLAKELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITQSLFSSRVAEIKVNWFKNKEEMLSVLPKLDTSLEEYLNLHEELMDVEKLQTKLMEEMEFLEGAESTEHPSHTLQHRF-------SEHTQLQTQQRAVQ 2507

HSP 2 Score: 79.337 bits (194), Expect = 1.825e-13
Identity = 45/148 (30.41%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            L+K+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL   +   NT   +       E E  +++   A  +L   E + GL+  S    G    WI ++A    GR E A  +++E++
Sbjct:  949 LDKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLT-EMKNNNTPQGT-------EFELTVMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHL 1088
[Close]
BLAST of SMG-1 vs. Ensembl Xenopus
Match: SMG1 (SMG1 phosphatidylinositol 3-kinase-related kinase [Source:NCBI gene;Acc:100145499])

HSP 1 Score: 477.633 bits (1228), Expect = 4.315e-134
Identity = 290/864 (33.56%), Postives = 469/864 (54.28%), Query Frame = 3 
Query: 5190 EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-----------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            ++  + +E ++K+W + V   FSL+  +  AYF+FLK        D    +   ++ +K  T      A LR+L L+ K +  LR  +   ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A   ++   LI+YP +VGSIS                               E    S P                       Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE   + T+   ETP E WF + + E I + +E++++P+N     ++W   K   +++L+      K      R  +L L+L+++SP L  + ++ I LPG     +  ++ S+  +I+ILPTKTKPKKF FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+ IN  ES  +H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N + +        RP+++Y+ K+ P L+A  + + + SR  WP+N++  V  EL   T P+LL+KELWC   + + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    +E+++     L   L    +  + + +++    K ++ +++L G E+        Q  +       S H +L  Q+R  Q
Sbjct: 1678 DLEEKASEGLIKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGRVSLDEDDPRLHLNIPSKQSTDDVIVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA---HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDELKNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYGEAIGNALEKLRNPSNPANPGNSWMPFK---QIMLSLQQRAQK------RASYL-LRLEEISPCLTAMTNTEIALPGEVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINSKESPHFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPAMVP-------RPSELYYSKISPALKAVGLSLDV-SRRDWPLNVMKSVLEELMEATPPNLLAKELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITQSLFSSRVAEIKVNWFKNKEEMLSVLPKLDTSLEEYLNLHEELMDVEKLQTKLMEEMEFLEGAESTEHPSHTLQHRF-------SEHTQLQTQQRAVQ 2507

HSP 2 Score: 79.337 bits (194), Expect = 1.935e-13
Identity = 45/148 (30.41%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            L+K+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL   +   NT   +       E E  +++   A  +L   E + GL+  S    G    WI ++A    GR E A  +++E++
Sbjct:  949 LDKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLT-EMKNNNTPQGT-------EFELTVMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHL 1088
[Close]
BLAST of SMG-1 vs. Ensembl Xenopus
Match: SMG1 (SMG1 phosphatidylinositol 3-kinase-related kinase [Source:NCBI gene;Acc:100145499])

HSP 1 Score: 477.248 bits (1227), Expect = 4.736e-134
Identity = 290/864 (33.56%), Postives = 469/864 (54.28%), Query Frame = 3 
Query: 5190 EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-----------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            ++  + +E ++K+W + V   FSL+  +  AYF+FLK        D    +   ++ +K  T      A LR+L L+ K +  LR  +   ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A   ++   LI+YP +VGSIS                               E    S P                       Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE   + T+   ETP E WF + + E I + +E++++P+N     ++W   K   +++L+      K      R  +L L+L+++SP L  + ++ I LPG     +  ++ S+  +I+ILPTKTKPKKF FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+ IN  ES  +H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N + +        RP+++Y+ K+ P L+A  + + + SR  WP+N++  V  EL   T P+LL+KELWC   + + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    +E+++     L   L    +  + + +++    K ++ +++L G E+        Q  +       S H +L  Q+R  Q
Sbjct: 1679 DLEEKASEGLIKLWKKVVDRIFSLYKLSCSAYFTFLKLNAGRVSLDEDDPRLHLNIPSKQSTDDVIVMATLRLLRLLVKHAGELRQYLEQGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVA---HDSPHLILYPAIVGSISLSNESQSSGTKLSSAIPTLLGNIQDDELMGVEGEEGSPPASQESKDELKNALNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVCSITSAPSETPHEKWFQDTYGEAIGNALEKLRNPSNPANPGNSWMPFK---QIMLSLQQRAQK------RASYL-LRLEEISPCLTAMTNTEIALPGEVSDRDTITIHSVGSNITILPTKTKPKKFIFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFATINSKESPHFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPAMVP-------RPSELYYSKISPALKAVGLSLDV-SRRDWPLNVMKSVLEELMEATPPNLLAKELWCSCASPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIECALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITQSLFSSRVAEIKVNWFKNKEEMLSVLPKLDTSLEEYLNLHEELMDVEKLQTKLMEEMEFLEGAESTEHPSHTLQHRF-------SEHTQLQTQQRAVQ 2508

HSP 2 Score: 79.337 bits (194), Expect = 1.887e-13
Identity = 45/148 (30.41%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            L+K+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL   +   NT   +       E E  +++   A  +L   E + GL+  S    G    WI ++A    GR E A  +++E++
Sbjct:  950 LDKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLAIMRVGLMAGQPAVTVRHGFDLLT-EMKNNNTPQGT-------EFELTVMMVVEALCELQCPEAIQGLAVWSSAVAGKSLSWISSVALHADGRFEKAAVEYQEHL 1089
[Close]
BLAST of SMG-1 vs. Ensembl Mouse
Match: Smg1 (SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) [Source:MGI Symbol;Acc:MGI:1919742])

HSP 1 Score: 484.567 bits (1246), Expect = 2.448e-136
Identity = 360/1170 (30.77%), Postives = 579/1170 (49.49%), Query Frame = 3 
Query: 4395 KWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIER--------ELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLN-TKSLLTLFMWLCNEKSKFP---KFCNDAKISSNLQFL-------IELAEVPWINGLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL--ATKLENQGFSSETICNIEL-----LLKSNFC-PSQMK--------TESDWFGDCYEDSGFLVELRQSILALD--PEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-----------------------------------------ENMNNSSP--------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            K+ R   N +    L++      LGK    Q  + + +    Q Q++         E  KLL+   +   ++++L+S          + S   S+K +    KS+LTL  W+  E  +     +    A+   NL  L       + L E+P  N +    P+  S E T    V +   +  QL  L+S    +    KS+ ALA W     R + +     E + L    K E Q    +TI   E      +L    C P+ ++        TES+   D  +D    V  RQ I +     E+     E V+K+W + V   FSL+  +  AYF+FLK        D    +   S   +  T      A LR+L L+ K +  LR  + + ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   LI+YP +VG+IS                                         ++ N   P              Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE  ++ T    ETP E WF + + + I + +E++K+P+N  +   +W   K   E++L+       ++ +  +     L+LD++SP LA + ++ I LPG     +  ++ S+   I+ILPTKTKPKK  FL ++GK Y YL+KGLEDL LDER+MQ L I NTMF+ IN  E+ ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N S +        RP+++Y+ K+ P L+   + + + SR  WP++++  V  EL   T P+LL+KELW      + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    ++++++    L   L+   S  + + +++    K L+ I++L G E  +      Q  Y       S H +L  Q+R  Q
Sbjct: 1428 KFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSS---------CAISFCKSAKAEYAVAKSILTLAKWVQAEWKEISGQLRQVYRAQQQQNLSGLSTLSRNILALIELPSANTVGEEHPRIES-ESTVHIGVGEPDFILGQLYHLSSVQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITESE---DNEDDDMVDVIWRQLISSCPWLSELDENATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQVLLDEDDPRLHLSHRAEQSTDDVIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPH---LILYPAIVGTISLSSESQASGNKYSSAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIDNALEKLKTPSNPAKPGSSWIPFK---EIMLS-------LQQRAQKRASYILRLDEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPSIVP-------RPSELYYSKIGPALKTVGLSLDV-SRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDSSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRY-------SEHTQLQTQQRAVQ 2548

HSP 2 Score: 80.4925 bits (197), Expect = 5.789e-14
Identity = 46/148 (31.08%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL        T  S        E+E  I++   A  +L   E + G++  S    G    WI ++A +  GR E A  +++E++
Sbjct:  988 LEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTNSLTQGS--------ELEVTIMMVVEALCELHCPEAIQGIAVWSSSAVGKNLLWINSVAQQAEGRFEKASVEYQEHL 1127
[Close]
BLAST of SMG-1 vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028])

HSP 1 Score: 159.458 bits (402), Expect = 7.940e-38
Identity = 102/374 (27.27%), Postives = 177/374 (47.33%), Query Frame = 3 
Query: 6150 PGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINL 7271
            P +   +++  P PG +   L   D  + IL +  KPKK     ++GK Y  + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V     L  +  +            + + C      ++ +S  +SE+        ++ + L P+                       VF+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG + +VPE VPFRLT  + N  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++ GH       K  +N +  ++++++   ++++
Sbjct: 2271 PSVLGAHANHDPFPG-HWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELRQC------MLPKSAALSEK------LKVFQELLLPRHPP--------------------VFHEWFLRTFPD------------PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVK-GH------SKAPLNETGEVVNEKAKTHVLDI 2592
[Close]
BLAST of SMG-1 vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028])

HSP 1 Score: 159.073 bits (401), Expect = 8.343e-38
Identity = 102/374 (27.27%), Postives = 177/374 (47.33%), Query Frame = 3 
Query: 6150 PGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINL 7271
            P +   +++  P PG +   L   D  + IL +  KPKK     ++GK Y  + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V     L  +  +            + + C      ++ +S  +SE+        ++ + L P+                       VF+E    T PD              +WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG + +VPE VPFRLT  + N  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++ GH       K  +N +  ++++++   ++++
Sbjct: 2265 PSVLGAHANHDPFPG-HWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGKELRQC------MLPKSAALSEK------LKVFQELLLPRHPP--------------------VFHEWFLRTFPD------------PTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFEVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVK-GH------SKAPLNETGEVVNEKAKTHVLDI 2586
[Close]
BLAST of SMG-1 vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202])

HSP 1 Score: 140.584 bits (353), Expect = 4.025e-32
Identity = 89/307 (28.99%), Postives = 146/307 (47.56%), Query Frame = 3 
Query: 6258 PKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEG--HPIRPTDIYWQKLRPKL-EAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCS--INSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            PK    + ++GK    L KG +DLR D  + Q+  + NT+  +  E    K  I TY V PL  R+G   ++E  T                                + E  + SE+G     RP D    + + K+ E  K        EK+      + F  + ++  P       +C    ++   W+   + +TRS A   I+G+ LGLGDRH+ N+L+N  + +++HID  V F++G  L  PE VPFRL+  I +  G   V G+FR  CE   E+++ SQ+++LT++++ ++DP+ DW+
Sbjct: 2706 PKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSG---VLEWCTGTVP----------------------------IGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSF----EEKY------DTFMTICQNFEPVF---RYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWT 2968
[Close]
BLAST of SMG-1 vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202])

HSP 1 Score: 140.584 bits (353), Expect = 4.060e-32
Identity = 89/307 (28.99%), Postives = 146/307 (47.56%), Query Frame = 3 
Query: 6258 PKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEG--HPIRPTDIYWQKLRPKL-EAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCS--INSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            PK    + ++GK    L KG +DLR D  + Q+  + NT+  +  E    K  I TY V PL  R+G   ++E  T                                + E  + SE+G     RP D    + + K+ E  K        EK+      + F  + ++  P       +C    ++   W+   + +TRS A   I+G+ LGLGDRH+ N+L+N  + +++HID  V F++G  L  PE VPFRL+  I +  G   V G+FR  CE   E+++ SQ+++LT++++ ++DP+ DW+
Sbjct: 2709 PKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSG---VLEWCTGTVP----------------------------IGEYLVNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSF----EEKY------DTFMTICQNFEPVF---RYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWT 2971
[Close]
BLAST of SMG-1 vs. UniProt/SwissProt
Match: sp|Q8BKX6|SMG1_MOUSE (Serine/threonine-protein kinase SMG1 OS=Mus musculus OX=10090 GN=Smg1 PE=1 SV=3)

HSP 1 Score: 484.567 bits (1246), Expect = 1.712e-135
Identity = 360/1170 (30.77%), Postives = 579/1170 (49.49%), Query Frame = 3 
Query: 4395 KWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIER--------ELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLN-TKSLLTLFMWLCNEKSKFP---KFCNDAKISSNLQFL-------IELAEVPWINGLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL--ATKLENQGFSSETICNIEL-----LLKSNFC-PSQMK--------TESDWFGDCYEDSGFLVELRQSILALD--PEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-----------------------------------------ENMNNSSP--------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            K+ R   N +    L++      LGK    Q  + + +    Q Q++         E  KLL+   +   ++++L+S          + S   S+K +    KS+LTL  W+  E  +     +    A+   NL  L       + L E+P  N +    P+  S E T    V +   +  QL  L+S    +    KS+ ALA W     R + +     E + L    K E Q    +TI   E      +L    C P+ ++        TES+   D  +D    V  RQ I +     E+     E V+K+W + V   FSL+  +  AYF+FLK        D    +   S   +  T      A LR+L L+ K +  LR  + + ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   LI+YP +VG+IS                                         ++ N   P              Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE  ++ T    ETP E WF + + + I + +E++K+P+N  +   +W   K   E++L+       ++ +  +     L+LD++SP LA + ++ I LPG     +  ++ S+   I+ILPTKTKPKK  FL ++GK Y YL+KGLEDL LDER+MQ L I NTMF+ IN  E+ ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N S +        RP+++Y+ K+ P L+   + + + SR  WP++++  V  EL   T P+LL+KELW      + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    ++++++    L   L+   S  + + +++    K L+ I++L G E  +      Q  Y       S H +L  Q+R  Q
Sbjct: 1428 KFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSS---------CAISFCKSAKAEYAVAKSILTLAKWVQAEWKEISGQLRQVYRAQQQQNLSGLSTLSRNILALIELPSANTVGEEHPRIES-ESTVHIGVGEPDFILGQLYHLSSVQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITESE---DNEDDDMVDVIWRQLISSCPWLSELDENATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQVLLDEDDPRLHLSHRAEQSTDDVIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPH---LILYPAIVGTISLSSESQASGNKYSSAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIDNALEKLKTPSNPAKPGSSWIPFK---EIMLS-------LQQRAQKRASYILRLDEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPSIVP-------RPSELYYSKIGPALKTVGLSLDV-SRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDSSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRY-------SEHTQLQTQQRAVQ 2548

HSP 2 Score: 80.4925 bits (197), Expect = 4.050e-13
Identity = 46/148 (31.08%), Postives = 71/148 (47.97%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL        T  S        E+E  I++   A  +L   E + G++  S    G    WI ++A +  GR E A  +++E++
Sbjct:  988 LEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTNSLTQGS--------ELEVTIMMVVEALCELHCPEAIQGIAVWSSSAVGKNLLWINSVAQQAEGRFEKASVEYQEHL 1127
[Close]
BLAST of SMG-1 vs. UniProt/SwissProt
Match: sp|Q96Q15|SMG1_HUMAN (Serine/threonine-protein kinase SMG1 OS=Homo sapiens OX=9606 GN=SMG1 PE=1 SV=3)

HSP 1 Score: 482.641 bits (1241), Expect = 6.829e-135
Identity = 360/1173 (30.69%), Postives = 577/1173 (49.19%), Query Frame = 3 
Query: 4395 KWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIER--------ELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLN-TKSLLTLFMWLCNEKSKFPK-------------FCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTD---VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL--ATKLENQGFSSETICNIEL-----LLKSNFC-PSQMK--------TESDWFGDCYEDSGFLVELRQSILALD--PEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK--------DATPTKAKYSLCNKNKT-----TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-----------------------------------------ENMNNSSP--------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQ 7562
            K+ R   N +    L++      LGK    Q  + + +    Q Q++         E  KLL+   +   ++++L+S          + S   S K +    KS+LTL  W+  E  +                F   + +S N+  LIEL   P +N +    P+  S E T    V +   +  QL  L+S    +    KS+ ALA W     R + +     E + L    K E Q    +TI   E      +L    C P+ ++        TES+   D  ED    V  RQ I +     E+     E V+K+W + V   FSL+  +  AYF+FLK        D    +   S   +  T      A LR+L L+ K +  LR  + + ++T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   LI+YP +VG+IS                                         ++ N   P              Y  I   L   N  +V +V + + ELRR+TVLWDELW+  L Q +  + ++  QL+ E+ ++ + + L+ ++   I++ K+ ++++  VF LE  ++ T    ETP E WF + + + I + +E++K+P N  +   +W   K   E++L+       ++ +  +     L+L+++SP LA + ++ I LPG     +  ++ S+   I+ILPTKTKPKK  FL ++GK Y YL+KGLEDL LDER+MQ L I NTMF+ IN  E+ ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N   +        RP+++Y+ K+ P L+   + + + SR  WP++++  V  EL   T P+LL+KELW      + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V  I+++ ++++LTL++ F++DP+VDW++G E+G  G+  GG      SK    KR +E  I  + F S    I+ +    ++++++    L   L+   S  + + +++    K L+ I++L G E  +      Q  Y       S H +L  Q+R  Q
Sbjct: 1430 KFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSS---------CAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIEL---PSVNTMEEEYPRIES-ESTVHIGVGEPDFILGQLYHLSSVQAPE--VAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITESE---DNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPH---LILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFK---EIMLS-------LQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA----LQAQKAQDSYQTPQNPGIVP-------RPSELYYSKIGPALKTVGLSLDV-SRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQ--SKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRY-------SEHTQLQTQQRAVQ 2550

HSP 2 Score: 79.7221 bits (195), Expect = 7.917e-13
Identity = 47/148 (31.76%), Postives = 73/148 (49.32%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV 3740
            LEK+ YN YEGC        K I TFF TN+  C +W  ++RL I+ +   +GQ +  + HG  LL     +  T S S       E+E  I++   A  +L   E + G++  S    G    WI ++A +  GR E A  +++E++
Sbjct:  990 LEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLT----EMKTTSLSQGN----ELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHL 1129
[Close]
BLAST of SMG-1 vs. UniProt/SwissProt
Match: sp|Q70PP2|SMG1_DROME (Serine/threonine-protein kinase Smg1 OS=Drosophila melanogaster OX=7227 GN=nonC PE=1 SV=2)

HSP 1 Score: 392.119 bits (1006), Expect = 1.451e-107
Identity = 224/691 (32.42%), Postives = 373/691 (53.98%), Query Frame = 3 
Query: 5196 TSQMAEEVVKIWLEFVTHHFSLHIAAAEAYF---SFLKDATPTKA----------KYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSP-------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-------LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNK-YHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSS 7166
            T +  + +++IW   + + +  +  AA +YF   SF   + P K           +  + + N  T  LR+L LI K +  L++ +   + T+P   W  +IPQLF+RL H +  +R  + +LL RLA S     +L+I+P +VG+  E  + ++P             Y  +   L +   + V+ V + +KELRR+ +LWDE W+ SL   Y+    +   L ++       DD + K+     ++N      +  LE     T+  PET  E  F   F   I  T++ ++     R + +AW K+K L  ++  +SN      + RG     +LK+  +SP L  I    I +PG++          + S++  + +LPTKTKPKK  F  +NG+ Y++L+KG+EDL LDER+MQ L I+N + +  ++   N  Y    Y V PLG ++GLI  V+  T +F+LYK+ Q R                       +   +    P R TD+++ KL P L    + +  D R +WP+++L++V +EL+++T  DLL++ELWC + N+  W +S   F R  +VM ++G+ +GLGDRHLDN+L+N  +G ++HIDYNVCF+KG +L++PEKVPFRLT  +    G   + G FR+ CE V +++++ ++++LTL++ F++DP+VDW++
Sbjct: 1548 TPEALDAILQIWRRAIANTYDYYKDAARSYFQYLSFKSGSGPEKPEGEGVVSQRERLHVDDSNLVTTTLRLLRLIVKHASGLQEVLEQGLHTTPIAPWKVIIPQLFSRLNHHEPYVRKSVCDLLCRLAKSR---PQLVIFPAVVGANREQQDATAPPATARPTTEDACCYGYLLGELSKQAPEAVQHVKLMVKELRRVCLLWDEYWIHSLAHIYNTYVSRVSALATDFRP----DDHEGKNN----RFNVWRPQLLADLEALVAVTSRPPETTYERSFRKRFDAPIRLTVDALRH----RRYPEAWDKLKQLYHIL--QSN------MIRGSGS--TLKMQSISPVLCGIGRMRISMPGLDAHGPDGDQVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRAHHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQV----------------AGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVS-DPRRQWPISVLLQVLDELSQETPNDLLARELWCQAGNAAEWRQSVRRFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRTLRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDWTT 2196

HSP 2 Score: 66.6254 bits (161), Expect = 7.062e-9
Identity = 48/200 (24.00%), Postives = 86/200 (43.00%), Query Frame = 3 
Query: 3267 VNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLL 3866
            ++L++  LD LEK+ YN  EG      P  K +  FF  N   C  WF ++R+ +V +A +  Q   VI +  Q+L              +K   P     IV  + +       ++L GL   +       + W++  AD+  G+ E AL+ +   +         +L SE+   TR+    S  + C++++    +L+
Sbjct:  919 LSLLLGFLDALEKLIYNAAEGSAFALRPPEKQVAAFFRLNNPTCQSWFNRIRIGVVIIAMHVQQPELVIRYAQQIL------------VNSKTQDPTYSQAIVYMAWSLVSCQEADSLRGLRLWARGKSCKSYKWLKYAADQAAGKRESALAGYRTILAEK------ELQSELEPHTRQFVV-SQMMQCLQDLGQWSQLV 1099
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BLAST of SMG-1 vs. UniProt/SwissProt
Match: sp|Q61CW2|SMG1_CAEBR (Serine/threonine-protein kinase smg-1 OS=Caenorhabditis briggsae OX=6238 GN=smg-1 PE=3 SV=3)

HSP 1 Score: 345.895 bits (886), Expect = 1.004e-93
Identity = 231/730 (31.64%), Postives = 361/730 (49.45%), Query Frame = 3 
Query: 5226 IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTT-ANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS--------ENMNNS-----SPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDL--KHKDVILKLKYNSIIQAAVFILERTKNATNMI-PETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK------SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFS--KINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDS-REKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSS--------GIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDL 7313
            +W     H          +YF F+ + +          + +TT A LRIL ++ K    L D I + +  +    W  ++PQLFARL H    IR  + +L+ R+  ++ +    +++  + G+ S        E  N+      +    ++  + ++   LV +V  F+ EL RI +L +E W   LG    E+ K+   +++E  K D    L  K KD I+  K   + +    +L+     T +  PET  E  F N F+E +T    E K+ N       +W   K L       +N       K+G   F   +  D+S  LA +  S +P+PG  +       S+  +  +++ILPTKT+PKK  F+ ++GK  ++L+KG EDL LDERVMQ L + N M    K    +  +Y    Y V PLG R+GLI+ VE AT +F +Y++ QM+ K        K     NG+ V E           +PT++Y   +R    A  ID  I S R KWP  IL EVF+ L   T  DL+S+E+W  + +S  W+  +  + RS AVM ++G  LGLGDRHLDNLLV+   G ++HIDYN+CFDKG  L++PE VPFRL+  + +  GP  + G FR SC +V   ++     +  L+D F+FDP+VDW+S        G+      +  G  +   + + L D   + F + +   Q+++++  +DL
Sbjct: 1406 LWEAASAHRRKFLCITVSSYFQFIHNMSGDFECLPYSKREETTLATLRILEMLVKHGEVLVDVINDGLSRTNVHVWKEILPQLFARLSHPSDHIRKTLVDLISRVCTAAPHA---VVFQVVSGAASSTEVSDLEEQQNDDRNRVRACCEQLETKMAQSYPNLVRDVRQFVAELERINLLNEEKWSVVLGTMEHEMEKRLALIKAENAKTDFSMHLMPKQKDEIISKKTKLLTRQIFDVLDELYEKTIVAQPETENEKEFFNTFSEMLTKAHTESKN-NRYNSPEASWAPFKNLVSNFAHRTN-------KKGMQTF---QTADISQYLATLGKSCVPMPGQESVEFDRVVSIARVADNVTILPTKTRPKKLGFIGSDGKQLAFLFKGREDLHLDERVMQFLRLCNVMLQSEKGKSRQIAEYQAHHYAVIPLGPRSGLIKWVEGATPIFHIYRKWQMKEKAL------KQATKKNGETVPEIE---------KPTNMYHNMIRQAFTAHNIDAIIASDRSKWPAQILEEVFDGLCSKTPTDLISREIWMRANDSTAWWAVTKRYARSLAVMSMVGSVLGLGDRHLDNLLVDLKYGHVVHIDYNICFDKGKILRIPETVPFRLSRNMRHALGPSDMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHDNISTSGGVSLALQLAVYGSSWKAKARERLTDTIEL-FQLRVTELQALWMSNREDL 2105
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BLAST of SMG-1 vs. UniProt/SwissProt
Match: sp|O01510|SMG1_CAEEL (Serine/threonine-protein kinase smg-1 OS=Caenorhabditis elegans OX=6239 GN=smg-1 PE=1 SV=3)

HSP 1 Score: 340.502 bits (872), Expect = 5.124e-92
Identity = 238/784 (30.36%), Postives = 392/784 (50.00%), Query Frame = 3 
Query: 5226 IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTT-ANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNS--------------SPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLK---HKDVILKLKYNSIIQAAVF-ILERTKNATNM-IPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK------SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMF--SKINEHES-NKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDS-REKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYG-------SFDGGKYAVNSSKSLIDKRSVEFI-INLNNFQSVFITIEDDL----KSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLR 7451
            IW     H       A  +YF F+++ +          K +TT A LRIL L+ K    L D I + +  +    W  ++PQLFARL H  + IR  + +L+ ++  ++ +    +++  + G+ S + +                +    ++  + ++   LV++V  F+ EL RI +L +E W   +G    E+ K+   +++E  K +S   L      D+I+K     ++   +F +L+     T +  P++  E  F   FAE +T+  +E +          +W   K L    +  ++       K+G   F   + +D+SP LA +++S +P+PG  +       S+  + + ++ILPTKT+PKK  F+ ++GK  ++L+KG EDL LDERVMQ L + N M    K    +S   Y    Y V PLG R+GLI+ VE AT +F +Y++ QM+ K        K     NG+ V E           RP+++Y   +R      KID  I S R KWP  IL EVF  L   T  DL+S+ELW  + ++  W+  +  ++RS AVM ++G  LGLGDRHLDNLLV+   G ++HIDYN+CFDKG +L++PE VPFRLT  + +  GP  + G FR SC +V   ++     +  L+D F+FDP+VDW+S   +   G       +  G  +   + + L D  ++E + + ++  Q++++   DDL    K   E L+++   L  +   +    K   E++ A  +   + + LR
Sbjct: 1413 IWKMVRDHRTKFLSIAVTSYFQFIQNMSGDCDNLPYSKKEETTLATLRILELLVKHGDVLIDVINDGLNKTNVHIWKEILPQLFARLSHPSEHIRKTLVDLISKICTAAPHA---VVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCEKLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIVK--RTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSP-EKSWIPFKNLIANFVHRNS-------KKGMQTF---ETEDISPYLASLSNSCVPMPGQESVEFDRVVSISRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKAL------KQATKKNGETVPEIE---------RPSNMYHNMIRLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGKNLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHEHTATSGVSLALQLAVYGSNWKTKAKERLTD--AMELLNLRMSEVQTLWLANRDDLLHWMKQVTECLLIENSMLGANAIYAQQRVKAGTELREAVTRHHALAKELR 2163
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BLAST of SMG-1 vs. TrEMBL
Match: H9XVZ7 (SMG-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 6787.97 bits (17610), Expect = 0.000e+0
Identity = 3441/3445 (99.88%), Postives = 3442/3445 (99.91%), Query Frame = 3 
Query:  534 MCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMXXXXXXXXIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNAXXXXXXXXXXXXXXXXILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDXXXXXXXXXXXXXXXXRITALKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECXXXXXXXXXXXXXXXXXXXXSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVEXXXXXXXXXXXXXXXDIVGKRSTXXXXXXXXXXXXXXXXXXXXSVAVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAWV 10868
            MCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYII IIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRL IVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPY EIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKV+VELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITALKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTDINLEIIEKDEKDKKYNNNNSVAVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAWV
Sbjct:   48 MCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIISIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLFIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYEEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVQVELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITALKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTDINLEIIEKDEKDKKYNNNNSVAVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAWV 3492

HSP 2 Score: 92.0485 bits (227), Expect = 4.417e-14
Identity = 41/42 (97.62%), Postives = 41/42 (97.62%), Query Frame = 3 
Query:   99 MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNT 224
            MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRN 
Sbjct:    1 MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNV 42
[Close]
BLAST of SMG-1 vs. TrEMBL
Match: A0A5N4AFW0 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_10179 PE=4 SV=1)

HSP 1 Score: 525.398 bits (1352), Expect = 1.604e-145
Identity = 405/1475 (27.46%), Postives = 704/1475 (47.73%), Query Frame = 3 
Query: 3267 VNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINW---------ARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLF--LSVVEKSSCKEVEIESFIVKLSSIQSI-----CDFPNTFTNPDIIL--INERLKLLKAANKGESFIVDCKNLSN----FSTTLPLPVISFCNTIQKRYNIPQ----CFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKE----INQQSNLSNSQLPIIQMQIE------------RELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQG--------FSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDP--EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNK----TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMN-------------------------------NSSPYHDIKKVLVENNRQLVE-----------EVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKI--DSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK-----SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHES-NKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDG--GKYAVNSSKSLIDK---------RSVEFIINLNNFQSVFITIEDDLKSCQEKLIL 7340
            V +++  ++ LEK  YN  EGC +  PP  K + TFF TN + C EW  ++R++IV +A ++GQ +  + HG  LL         +  +  K    + E  ++  ++A   L   E +YGL     +    K +W++  +D+   + E A+  ++  +  + D              + T +   + +   +I +CYK LN+   +++WK    S        +    ++N+           + C  KL++W  N+++          SW    ++ N E  L+   S +    C  + +      L++IQ I        P+ F    +++  +   LK +   +   +  +  +N  N      +T+   ++ +     +    P     C   +  +I+  R   N+     L       F+ +E    +N++  L +  L ++Q   E            +E +KLL+  ++ K  +  L ++   ++         H  K Q+++K LL L  WL   +S    F      S  ++ L+ L E+    G  ++     ++ K  Q SV    +                K++ A   WC    R +  I  N++  +L T+ +N           S +    I  +L      SQ  T ++   D  E S  +  +R+ +L++     +  Q  + +++IW       +  +  + ++YF +L  A   +      N+N      TA LR+L LI K +  L++ I N +  +P   W  +IPQLF+RL H +  +R  +SE L R+A    +   LI +P +VG++   +                                  S   + K VL    + +VE           +V + +KELRRIT+LWDELW+ +L Q   E+ ++ HQL+ EI+K+  ++  D   K  ++  KY  I++  +FILE+ +  T++ PETP E  F   +A  I   +E++K+P++  +  ++W+ +K LQ           K + K  +    SLK+ D+SP LA +  ++I +PG+        ++ ++  H+SILPTKTKPKK  F  ++G+ Y+YL+KGLEDL LDER+MQ L IANTM ++ ++  S N Y    Y V PLG R+GLI  V+  T +F+LYKR Q R     +    ++  SN+   V            +RP+++++ KL P L+   +    +SR++WP+ IL +V  EL  +T  DLL+KELWC ++++  W++   N++ S AVM  +G+ +GLGDRHLDN+LV+ ++G+++HIDYNVCF+KG +L+VPEKVPFRLT  I    G   V G+FR++CENV + +++ ++++LTL++ F++DP+VDW+ G E     +F G  G      S+  +++         R  E  I+ N+ ++    I DD+   +EKL L
Sbjct:  964 VRMLLQFMEHLEKAIYNAAEGCAIAMPPAPKPVRTFFYTNASTCKEWLSRIRVVIVIVALHAGQSTVALRHGHALL--------ANLVAGNKTNTVDFERAVMYVTLALLNLRENEAIYGLYTWCKKIADRKLEWVKFASDQANKKYESAVKNYKTLIERNKD-------------EKDTDTQVQYFMS-SQIVNCYKELNSWSEINEWKNYETSLGHGDNGLKHFFTTVNYDCINTLSNGDTIRCANKLNQW--NIEETN--------SWSTYEILRNTESDLYNVASNINAPKCAYL-LAKTDTSLATIQEIMQDNLLSLPSEFLQTFLLMHYVANGLKTILNNSLASNVFLVSENFENDIEKIDSTILTKILWWSEYFSRDQQNPGFNTFCSSLRLHIIRRARKEKNY----ELACLHLNRFMAQEGMFALNERLPLEDIGLLLLQKTAEFSTCTFDFAKSMKEAIKLLYATEENKQLVFNLCANASTAISKNADRLGRHDMK-QISSKILLRLATWLQGTESNL--FTVTDMTSPLVKLLLVLPEIGINVGTNIIPTNEMAIGKLLQFSVQQCITM--------------GKNWFAFGTWCYRWGRKI--IDHNSDITNLLTEEDNMAVRRCLPVDVSEDDFARILSIL------SQRPTTNEDDIDLNETST-VEAIREQLLSVPVFYNVHEQQLQSLIQIWKNSQKRIYGYYEMSVDSYFKYLHLAVNAEN----INRNNECSTITATLRLLRLIVKHALVLQNVIENGLANTPTHPWKVIIPQLFSRLNHPEAYVRERVSEFLCRVA---EDAPHLITFPAVVGAVEGGVKFDFSEISMPKDCFSQSNENNEDNELNEIEDAYDSDTEETKNVLQSCFKSMVETLSKQAPETITQVQMLVKELRRITLLWDELWLGTLVQYNSEIIQRQHQLEVEIEKVNDNAHLDKDEKISLITEKYRIIMKPIIFILEQLQLVTSVEPETPHEKQFQERYAPIIKQVLEKLKNPDHPEKPQESWQPLKMLQS----------KFQQKAHKRTAYSLKMQDISPLLAGLKDTVIAMPGLTTSIRTQVTISNVSNHVSILPTKTKPKKLVFYGSDGQTYTYLFKGLEDLHLDERIMQFLSIANTMMAQGSDESSHNLYRARHYSVIPLGPRSGLISWVDGTTPVFALYKRWQQREGAKSNIKVGQSQRSNSNPNVG----------VLRPSELFYNKLNPLLQEHGVK-NPESRKEWPLAILKQVLTELMAETPNDLLAKELWCHAVSAGEWWQMIRNYSYSVAVMSTLGYIIGLGDRHLDNVLVDLTSGEVVHIDYNVCFEKGKTLRVPEKVPFRLTPNIVEALGVTGVEGIFRLACENVLKTMKKGRETLLTLLEAFVYDPLVDWTVGGEGLAGTAFRGVAGNSLTRQSRKDLEREVTLSMYRVRCTEIKIDWNDNKT---EILDDIPQVEEKLAL 2344
[Close]
BLAST of SMG-1 vs. TrEMBL
Match: A0A1Y1N066 (Uncharacterized protein (Fragment) OS=Photinus pyralis OX=7054 PE=3 SV=1)

HSP 1 Score: 522.702 bits (1345), Expect = 8.430e-145
Identity = 403/1471 (27.40%), Postives = 701/1471 (47.65%), Query Frame = 3 
Query: 3267 VNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWA---------RLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLF--LSVVEKSSCKEVEIESFIVKLSSIQSI-----CDFPNTFTNPDIIL--INERLKLLKAANKGESFIVDCKNLSN----FSTTLPLPVISFCNTIQKRYNIPQ----CFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKE----INQQSNLSNSQLPIIQMQIE------------RELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGF--------SSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDP--EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMN-------------------------------NSSPYHDIKKVLVENNRQLVE-----------EVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKI--DSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK-----SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHES-NKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDG--GKYAVNSSKSLIDK---------RSVEFIINLNNFQSVFITIEDDLKSCQEKLIL 7340
            V +++  ++ LEK  YN  EGC +  PP  K + TFF TN + C EW  ++R++IV +A ++GQ +  + HG  LL         +  +  K    + E  ++  ++A   L   E +YGL     +    K +W++  +D+   + E A+  ++  +  + D              + T +   + +   +I +CYK LN+   +++WK    S        +    ++N+           + C  KL++W  N+++          SW    ++ N E  L+   S +    C  + +      L++IQ I        P+ F    +++  +   LK +   +   +  +  +N  N      +T+   ++ +     +    P     C   +  +I+  R   N+     L       F+ +E     N++  L +  L ++Q   E            +E +KLL+  ++ K  +  L ++   ++         H  K Q+++K LL L  WL   +S    F      S  ++ L+ L E+    G  ++     ++ K  Q SV    +                K++ A   WC    R +  I  N++  +L T+ +N           S +    I  +L      SQ  T ++   D  E S  +  +R+ +L++     +  Q  + +++IW       +  +  + ++YF +L  A   +        +  TA LR+L LI K +  L++ I N +  +P   W  +IPQLF+RL H +  +R  +SE L R+A    +   LI +P +VG++   +                                  S   + K VL    + +VE           +V + +KELRRIT+LWDELW+ +L Q   E+ ++ HQL+ EI+K+  ++  D   K  ++  KY  I++  +FILE+ +  T++ PETP E  F   +A  I   +E++K+P++  +  ++W+ +K LQ           K + K  +    SLK+ D+SP LA +  ++I +PG+        ++ ++  H+SILPTKTKPKK  F  ++G+ Y+YL+KGLEDL LDER+MQ L IANTM ++ ++  S N Y    Y V PLG R+GLI  V+  T +F+LYKR Q R     +    ++  SN+   V            +RP+++++ KL P L+   +    +SR++WP+ IL +V  EL  +T  DLL+KELWC ++++  W++   N++ S AVM  +G+ +GLGDRHLDN+LV+ ++G+++HIDYNVCF+KG +L+VPEKVPFRLT  I    G   V G+FR++CENV + +++ ++++LTL++ F++DP+VDW+ G E     +F G  G      S+  +++         R  E  I+ N+ ++    I DD+   +EKL L
Sbjct:  771 VRMLLQFMEHLEKAIYNAAEGCAIAMPPAPKPVRTFFYTNASTCKEWLSRIRVVIVIVALHAGQSTVALRHGHALL--------ANLVAGNKTNTVDFERAVMYVTLALLNLRENEAIYGLYTWCKKIADRKLEWVKFASDQANKKYESAVKNYKTLIERNKD-------------EKDTDTQVQYFMS-SQIVNCYKELNSWSEINEWKNYETSLGHGDNGLKHFFTTVNYDCINTLSNGDTIRCANKLNQW--NIEETN--------SWSTYEILRNTESDLYNVASNINAPKCAYL-LAKTDTSLATIQEIMQDNLLSLPSEFLQTFLLMHYVANGLKTILNNSLASNVFLVSENFENDIEKIDSTILTKILWWSEYFSRDQQNPGFNTFCSSLRLHIIRRARKEKNY----ELACLHLNRFMAQEGMFAPNERLPLEDIGLLLLQKTAEFSTCTFDFAKSMKEAIKLLYATEENKQLVFNLCANASTAISKNADRLGRHDMK-QISSKILLRLATWLQGTESNL--FTVTDMTSPLVKLLLVLPEIGINVGTNIIPTNEMAIGKLLQFSVQQCITM--------------GKNWFAFGTWCYRWGRKI--IDHNSDITNLLTEEDNMAVRRCLPVDVSEDDFARILSIL------SQRPTTNEDDIDLNETST-VEAIREQLLSVPVFYNVHEQQLQSLIQIWKNSQKRIYGYYEMSVDSYFKYLHLAVNAENINRNNECSTITATLRLLRLIVKHALVLQNVIENGLANTPTHPWKVIIPQLFSRLNHPEAYVRERVSEFLCRVA---EDAPHLITFPAVVGAVEGGVKFDFSEISMPKDCFSQSNENNEDNELNEIEDAYDSDTEETKNVLQSCFKSMVETLSKQAPETITQVQMLVKELRRITLLWDELWLGTLVQYNSEIIQRQHQLEVEIEKVNDNAHLDKDEKISLITEKYRIIMKPIIFILEQLQLVTSVEPETPHEKQFQERYAPIIKQVLEKLKNPDHPEKPQESWQPLKMLQS----------KFQQKAHKRTAYSLKMQDISPLLAGLKDTVIAMPGLTTSIRTQVTISNVSNHVSILPTKTKPKKLVFYGSDGQTYTYLFKGLEDLHLDERIMQFLSIANTMMAQGSDESSHNLYRARHYSVIPLGPRSGLISWVDGTTPVFALYKRWQQREGAKSNIKVGQSQRSNSNPNVG----------VLRPSELFYNKLNPLLQEHGVK-NPESRKEWPLAILKQVLTELMAETPNDLLAKELWCHAVSAGEWWQMIRNYSYSVAVMSTLGYIIGLGDRHLDNVLVDLTSGEVVHIDYNVCFEKGKTLRVPEKVPFRLTPNIVEALGVTGVEGIFRLACENVLKTMKKGRETLLTLLEAFVYDPLVDWTVGGEGLAGTAFRGVAGNSLTRQSRKDLEREVTLSMYRVRCTEIKIDWNDNKT---EILDDIPQVEEKLAL 2151
[Close]
BLAST of SMG-1 vs. TrEMBL
Match: A0A267EA24 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027692g1 PE=3 SV=1)

HSP 1 Score: 507.679 bits (1306), Expect = 4.662e-140
Identity = 319/1005 (31.74%), Postives = 510/1005 (50.75%), Query Frame = 3 
Query: 4524 MQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNE-----------KSKFPKFCNDA----KISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTD----------------VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRS--LDE------IGFNAETIDLATKLENQGFSSETICNIELLLKSNFC--PSQMKTESDWFGDCYEDSGFLVELRQSI-LALDPEITS-QMAEEVVK----IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNK-----TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENM----------------NNSSPYHD------------------IKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDV--ILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELI---LTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK-SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEG-HPI-RPTDIYWQKLRPKLEAAKIDIGID---------------------SREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGS 7193
            M +ER   KLLW   +    L  L + +  SL  + +D  L   K +LN KS+LTL  W+ +E           +S  PK    A     +S +L +L +L    + +G P            C +SV D                +  +LL+LASK        K++  LA WC   +R   LD       +       + A  L     ++E    +  +L   F   PS    +S       E +   V    +I  AL  ++   Q++E  ++    +W +     F+LH ++A++YF++L+ A        L           +A LR+L L+ K    L D ++     +P G W  +IPQLF+RL H    ++ C++ELL R+     +   L+++P +VGS +                   + ++P  D                  I   +   +  L+ +V +F+ E+RRITVLWDELW+ ++ Q  D+  ++  QL  E+ ++ + D L   D   ++  K+       ++ LER  + T++  ETP E+WF   F+E I  TI+ +++P++  + +  W+ IK L + +   +   + N  V    G      L L ++SP LA++ ++ +P+PG+  + +L  I   + ILPTKTKPK+  F ++NG+   YL+KGLEDL LDER+MQ LGI N +F+++N+ ES  Y   TY VTPLG R+GLIQMVE    LF+LYKR Q R     ++   +A          +       G H + RP+++++ K+RP LEA  I   +                      SR+ WP+++  EVF EL R+T  +LLSKELW  S+N+ +W+R+ +N++RS AVM I+G+ +GLGDRHLDN+L++   G+++HIDYNVCF+KG +LKVPE+VPFRLT  +    G   V G+FR+S E V   ++  ++ +LTL++ F++DP+VDW+ G+E G+ G+
Sbjct: 1613 MSLERAAAKLLWRRGQSLPGLYCLAAGMSRSLAADAADPLLRGQKSRLNAKSVLTLVKWIRSEAHSSLFSAVLTQSSVPKAQPRAHQFASVSRSLAYLCDLTRQEFSDGAP-----------KCPASVIDDDSRLHSLLLNFDTDALVGKLLLLASKLCPLHA--KAWHGLASWCYKEARRTVLDAANRKPNVELTQAEKETALSLLPATVTAEEQTRVLDILGQVFTKSPSIGADQSAGAATVTEATDLPVCTEAAIESALRSQLPGRQLSERSLRGLQSVWRQCCQRVFALHHSSAKSYFTYLRLAATGSDDNGLGGSGSDQSPVVSATLRLLRLLVKHPGELADCLLEGFGDTPTGPWRAIIPQLFSRLSHPYPAVQQCLTELLIRIGA---DYPHLVVFPAIVGSSAPAATEREPASAAAADANPEDEAAPEDDQAAEAAALDSGVLWCVSSICDKMTAADPALLGQVRLFVDEMRRITVLWDELWLGAISQQLDDTARRVDQLDEELRRLATSDALSAADKQNLVAQKHEVFFMPILYTLERLSSITSVPAETPHETWFQATFSEIINETIDAVRAPSDPGQPHATWQAIKHLYQFLQQKIRRHSPNGAVAGGGG------LSLAEISPALARLRATRVPMPGLGAELTLDGIQDEVQILPTKTKPKRLHFRASNGRVSPYLFKGLEDLHLDERIMQFLGITNALFARLNKLESPCYAARTYSVTPLGLRSGLIQMVETPIPLFTLYKRWQAREAMMLNYKPVRAQPQQQQQQQQQQQTEDPSGRHGVARPSELFFNKMRPALEAKGIVPPLPQQRQQQQAEAAAAAATAALAASRKDWPLSVCREVFAELVRETPNNLLSKELWLASLNAADWWRTLLNYSRSVAVMSIIGYVIGLGDRHLDNVLIDVGTGEIVHIDYNVCFEKGRNLKVPERVPFRLTQNLEAALGLTGVEGVFRLSAEKVLHTMRSDKEMLLTLLEAFVYDPLVDWTPGVEGGYTGA 2595

HSP 2 Score: 98.9821 bits (245), Expect = 2.806e-16
Identity = 49/103 (47.57%), Postives = 73/103 (70.87%), Query Frame = 3 
Query:  249 ASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDIL 557
            AS+ G++D+V++LI + AD N+ +  G+RPIHFAA  GHVTTV++L+  GAEV+  T   +TP+  AL+  MRDTV+KLL+ GA+L G+D   L+   ++  L
Sbjct:   69 ASYIGHKDIVRFLISSKADPNASTSLGYRPIHFAASEGHVTTVDILLNAGAEVSPLTADGDTPVALALKWGMRDTVRKLLNSGATLDGLDDASLKKYAKRGFL 171

HSP 3 Score: 94.3597 bits (233), Expect = 7.554e-15
Identity = 79/316 (25.00%), Postives = 146/316 (46.20%), Query Frame = 3 
Query: 3078 WDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCL--GFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFI-LCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEA----QKLSINWARLVCLTKLSKWDE 4004
            W CV  KLK      ++ T + IE+          +L  I ++R         S  P D   S   ++L ++ LEK+ +N YEGC L  G     KS++ FF TNK+ C+EWF + R +++ L         V      LL        T +S  A       +D ++L   +  ++G  + L+GL        G +   + A A++   +LE AL  +E+++++      I    E+RL +++T+  ++++  C+ +IA+C++ L N   L  W+++++ + +   +       Q   +N+    CL  + +W E
Sbjct: 1114 WFCVLNKLKVPPWNRAQDTFLAIED----------ALNRIVNQRL--------SANPADWHRSY-CVLLFMEQLEKLVFNAYEGCALLSGLSHF-KSVKYFFRTNKSTCLEWFHRTRPIVMQLCDRLDSPELVAREAFALLG------ETDASRYAN-----QDDTLLLLVKSLCRMGQADCLHGLYAWCETRLGRRLLCVRAAAERADSKLESALQLYEQHLQDLLM-NGIGRPGEVRLASKQTSGTAAYVRFCVTQIAECHEQLGNSRQLLAWQERLRKYAAEHALALPADCFQVPGVNFTYQACLAAMGEWSE 1397
[Close]
BLAST of SMG-1 vs. TrEMBL
Match: A0A267GHW8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027692g2 PE=3 SV=1)

HSP 1 Score: 507.294 bits (1305), Expect = 5.615e-140
Identity = 330/1081 (30.53%), Postives = 537/1081 (49.68%), Query Frame = 3 
Query: 4335 NTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLI---------SHSFTSFLGKEINQQSNLSNSQLPIIQ----MQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNE-----------KSKFPKFCNDA----KISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTD----------------VCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRS--LDE------IGFNAETIDLATKLENQGFSSETICNIELLLKSNFC--PSQMKTESDWFGDCYEDSGFLVELRQSI-LALDPEITS-QMAEEVVK----IWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNK-----TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENM----------------NNSSPYHD------------------IKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDV--ILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELI---LTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK-SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEG-HPI-RPTDIYWQKLRPKLEAAKIDIGID---------------------SREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGS 7193
            + +Q+R +    F      ++W     NF    +L+         S SF++      +  + + + +L  +     M +ER   KLLW   +    L  L + +  SL  + +D  L   K +LN KS+LTL  W+ +E           +S  PK    A     +S +L +L +L    + +G P            C +SV D                +  +LL+LASK        K++  LA WC   +R   LD       +       + A  L     ++E    +  +L   F   PS    +S       E +   V    +I  AL  ++   Q++E  ++    +W +     F+LH ++A++YF++L+ A        L           +A LR+L L+ K    L D ++     +P G W  +IPQLF+RL H    ++ C++ELL R+     +   L+++P +VGS +                   + ++P  D                  I   +   +  L+ +V +F+ E+RRITVLWDELW+ ++ Q  D+  ++  QL  E+ ++ + D L   D   ++  K+       ++ LER  + T++  ETP E+WF   F+E I  TI+ +++P++  + +  W+ IK L + +   +   + N  V    G      L L ++SP LA++ ++ +P+PG+  + +L  I   + ILPTKTKPK+  F ++NG+   YL+KGLEDL LDER+MQ LGI N +F+++N+ ES  Y   TY VTPLG R+GLIQMVE    LF+LYKR Q R     ++   +A          +       G H + RP+++++ K+RP LEA  I   +                      SR+ WP+++  EVF EL R+T  +LLSKELW  S+N+ +W+R+ +N++RS AVM I+G+ +GLGDRHLDN+L++   G+++HIDYNVCF+KG +LKVPE+VPFRLT  +    G   V G+FR+S E V   ++  ++ +LTL++ F++DP+VDW+ G+E G+ G+
Sbjct: 1535 DPVQQRQHREMNFGVSLPTVRWCIRQSNFATAEALLLGEIDKVCPSQSFSASADSGPDLLAAVESVRLARVSECDLMSLERAAAKLLWRRGQSLPGLYCLAAGMSRSLAADAADPLLRGQKSRLNAKSVLTLVKWIRSEAHSSLFSAVLTQSSVPKAQPRAHQFASVSRSLAYLCDLTRQEFSDGAP-----------KCPASVIDDDSRLHSLLLNFDTDALVGKLLLLASKLCPLHA--KAWHGLASWCYKEARRAVLDAANRKPNVELTQAEKETALSLLPATVTAEEQTRVLDILGQVFTKSPSIGADQSAGAATVTEATDLPVCTEAAIESALRSQLPGRQLSERSLRGLQSVWRQCCQRVFALHHSSAKSYFTYLRLAATGSDDNGLGGSGSDQSPVVSATLRLLRLLVKHPGELADCLLEGFGDTPTGPWRAIIPQLFSRLSHPYPAVQQCLTELLIRIGA---DYPHLVVFPAIVGSSAPAATEREPASAAAADANPEDEAAPEDDQAAEAAALDSGVLWCVSSICDKMTAADPALLGQVRLFVDEMRRITVLWDELWLGAISQQLDDTARRVDQLDEELRRLATSDALSAADKQNLVAQKHEVFFMPILYTLERLSSITSVPAETPHETWFQATFSEIINETIDAVRAPSDPGQPHATWQAIKHLYQFLQQKIRRHSPNGAVAGGGG------LSLAEISPALARLRATRVPMPGLGAELTLDGIQDEVQILPTKTKPKRLHFRASNGRVSPYLFKGLEDLHLDERIMQFLGITNALFARLNKLESPCYAARTYSVTPLGLRSGLIQMVETPIPLFTLYKRWQAREAMMLNYKPVRAQPQQQQQQQQQQQTEDPSGRHGVARPSELFFNKMRPVLEAKGIVPPLPQQRQQQQAEAAAAAATAALAASRKDWPLSVCREVFAELVRETPNNLLSKELWLASLNAADWWRTLLNYSRSVAVMSIIGYVIGLGDRHLDNVLIDVDTGEIVHIDYNVCFEKGRNLKVPERVPFRLTQNLEAALGLTGVEGVFRLSAEKVLHTMRSDKEMLLTLLEAFVYDPLVDWTPGVEGGYTGA 2593

HSP 2 Score: 98.9821 bits (245), Expect = 2.806e-16
Identity = 49/103 (47.57%), Postives = 73/103 (70.87%), Query Frame = 3 
Query:  249 ASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDIL 557
            AS+ G++D+V++LI + AD N+ +  G+RPIHFAA  GHVTTV++L+  GAEV+  T   +TP+  AL+  MRDTV+KLL+ GA+L G+D   L+   ++  L
Sbjct:   69 ASYIGHKDIVRFLISSKADPNASTSLGYRPIHFAASEGHVTTVDILLNAGAEVSPLTADGDTPVALALKWGMRDTVRKLLNSGATLDGLDDASLKKYAKRGFL 171

HSP 3 Score: 91.2781 bits (225), Expect = 7.195e-14
Identity = 78/316 (24.68%), Postives = 145/316 (45.89%), Query Frame = 3 
Query: 3078 WDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCL--GFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFI-LCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEA----QKLSINWARLVCLTKLSKWDE 4004
            W CV  KLK      ++ T + IE+          +L  I ++R         S  P D   S   ++L ++ LEK+ +N YEGC L  G     KS++ FF TNK+ C+EW  + R +++ L         V      LL        T +S  A       +D ++L   +  ++G  + L+GL        G +   + A A++   +LE AL  +E+++++      I    E+RL +++T+  ++++  C+ +IA+C++ L N   L  W+++++ + +   +       Q   +N+    CL  + +W E
Sbjct: 1115 WFCVLNKLKVPPWNRAQDTFLAIED----------ALNRIVNQRL--------SANPADWHRSY-CVLLFMEQLEKLVFNAYEGCALLSGLSHF-KSVKYFFRTNKSTCLEWLHRTRPIVMQLCDRLDSPELVAREAFALLG------ETDASRYAN-----QDDTLLLLVKSLCRMGQADCLHGLYAWCETRLGRRLLCVRAAAERADSKLESALQLYEQHLQDLLM-NGIGRPGEVRLASKQTSGTAAYVRFCVTQIAECHEQLGNCRQLLAWQERLRKYAAEHALALPADCFQVPGVNFTYQACLAAMGEWSE 1398
[Close]
BLAST of SMG-1 vs. Ensembl Cavefish
Match: smg1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase [Source:ZFIN;Acc:ZDB-GENE-061013-767])

HSP 1 Score: 487.649 bits (1254), Expect = 2.385e-137
Identity = 356/1150 (30.96%), Postives = 573/1150 (49.83%), Query Frame = 3 
Query: 4521 QMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNT-KSLLTLFMWLCNE-KSKFPKFCNDAK----------ISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQ-DNSDKSFMALAQWCLSRSRSLDEIGFNAETIDL-------ATKLENQGFSSETICNIELLLKSNFC-PSQMKTESDWFGDCYEDSGFLVEL--RQSILALDP---EITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLK---DATPTK---AKYSLCNKNK--------TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSIS-------------------------------ENMNNSSP-------------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLS--LKLDDVSPGLAKINSSLIPLPG----MNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKI-VEQFNYVR--KLEERSMHLELDIQKRQQQL-KLVSMEHSAFFNKILSAADFISLKLDIKN 7652
            +++IER   K+L+   +   ++++L+S          + S   S KC+    +S+LTL  WL  + K   P+     K          +S N+  L+EL       G+P ++      E T    V +    L  L   S NQ     KS+ ALA W     R + +     E + L         +L   G + E    I  +L    C P+ ++ E     +  +D   +V++  RQ +L+  P   ++  ++ E ++K+W   V   FSL+  +  AYF+FLK      P      K  L N+N           A LR+L L+ K +  LR+ +   + ++P   W  +IPQLF+RL H +  IR  +  LL R+A  S +   LI+YP +VGSIS                               E+   S+P                         Y  I   L   N  +V +V + + ELRR+T+LWDELW+  L Q      +  H LQ +   +     L  K  I++ K++++++  VF L+  ++ T    ETP E+WF   + E I + +E +K+P N      +W   K             I V L++   +  S  L+LD++SP LA + ++ + LPG     +  ++ ++   I+ILPTKTKPKK  FL ++GK+Y YL+KGLEDL LDER+MQ L I NTMF+K+N+ ES ++H   Y VTPLGTR+GLIQ V+ AT LF LYKR Q R       L+++    +     N   +        RP+++Y+ K+ P L+A  + + + SR  WP++++ +V  EL   T P+LL+KELWC     + W+R + ++ RS AVM ++G+ +GLGDRHLDN+L++ + G+++HIDYNVCF+KG SL+VPEKVPFR+T  I    G   V G+FR+SCE V +++++ ++++LTL++ F++DP+VDW++G E G  G+  GG      SK    KR +E  I  + F S    I+ +    +++++     +   +    S  + + +++    K L+ +++L G ++  E  I   +  YV   +L+ R   ++  IQ +   L + +S    AF    L A    SL  +I +
Sbjct: 1480 ELKIER--AKVLFTAGQSVAAMEMLSS---------CALSYCRSGKCERAACRSVLTLCKWLLADWKDLTPQLKQVVKKNTTTTTLSTLSKNIAGLLELPVEE--QGMPRIT-----TETTVSVGVGEADFVLGQLYQLSANQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPSGTTEEDKETIFSILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIWRQ-LLSSCPWLADVEDRVTEGLIKVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLELGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPH---LILYPAIVGSISLGGESQAAGNKLPSSLPTLLGNMQGEGLCGEESQAGSAPASQESGRGEELVLCSSEDQAMMQDCYSKIVDTLSSGNPTMVLQVQMLVGELRRVTLLWDELWLGVLQQ------QHMHVLQLQSIHLHYYPLLDEKMAIMREKHSALMRPVVFALDHVRSITAAPAETPHETWFQETYGEAIHNALERLKNPLNPANPASSWVPFK------------QIMVSLQQRAQKRASYLLRLDEISPRLASMANTEMALPGEVSATDAVTIHNVGNTITILPTKTKPKKLYFLGSDGKNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAV----LQAQKAQDSYQQPQNLPMVP-------RPSELYYSKIGPALKAVGLSLDV-SRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQMMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAESKQ--SKREMERDITRSLFSSRVAEIKVNWFKNRDEMLAVLPQVEMAVEEYLSLQEQLTQVEKVQAKLLEEMEFLEGADSRAEHPIHTLEHRYVEHTQLQSRQRTVQDAIQSKMSDLNQWISQYQDAFSR--LEATQLASLLQEISS 2573

HSP 2 Score: 80.8777 bits (198), Expect = 3.333e-14
Identity = 50/148 (33.78%), Postives = 74/148 (50.00%), Query Frame = 3 
Query: 3297 LEKMFYNCYEGC--CLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEE 3734
            LEK+ YN YEGC   L  PP  K I TFF TN+  C +W  ++R+ ++ +   SGQ +  I HG  LL          +SSA     PE+E  I +   A  +L   E + GL+  S    G    W+ ++A +  G+ E A  +++E
Sbjct:  989 LEKLMYNAYEGCANALTAPP--KGIRTFFYTNRQTCQDWLTRIRMALMRVGLLSGQPAVTIRHGFDLLT------EIKNSSAQG---PEMEVPITMLVEALCELRCPEAIQGLAAWSQANMGKSLAWVGSVALQAEGKFEKAALEYQE 1125
[Close]
BLAST of SMG-1 vs. Ensembl Cavefish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458])

HSP 1 Score: 150.214 bits (378), Expect = 3.066e-35
Identity = 102/351 (29.06%), Postives = 167/351 (47.58%), Query Frame = 3 
Query: 6210 LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIE----VFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRS 7250
            L   D  + IL +  KPKK     ++GK Y+ + K  +DLR D R+M+   + N    K  E      HI TY V PL    G+I+ V     L     RH                      I+N+  +  E+G  +   ++  + + PK  +      +  + K   ++L      VF++    T PD  S            WY S   + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG +  VPE VPFRLT  + +  GPM   GLFR +CE    +++  ++ +++++  F+ DP+V+WS  ++    GS    K   N S  ++++++
Sbjct: 2084 LSGFDDSVEILASLQKPKKISLRGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKCLRKDAESRRRDLHIRTYAVIPLNEECGIIEWVNNTAGL-----RH----------------------ILNK--LYKEKGIYLTGKELR-KMILPKTAS------LQEKLKLHKDVLCARHPPVFHDWFLRTFPDPTS------------WYNSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSLTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSKPVK----GSL---KTQANESGEIVNEKA 2379
[Close]
BLAST of SMG-1 vs. Ensembl Cavefish
Match: mtor (mechanistic target of rapamycin kinase [Source:NCBI gene;Acc:103042377])

HSP 1 Score: 139.043 bits (349), Expect = 8.440e-32
Identity = 58/146 (39.73%), Postives = 101/146 (69.18%), Query Frame = 3 
Query: 6726 IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            +EVF     +T+ D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++  +G+++HID+  CF+  ++  K PEK+PFRLT ++TN      ++G +RI+C  V E++++ +DS++ +++ F++DP+++W
Sbjct: 2253 VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNW 2398

HSP 2 Score: 113.235 bits (282), Expect = 5.191e-24
Identity = 97/414 (23.43%), Postives = 177/414 (42.75%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSLIGKRSR--SLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQC----YDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKS---PNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNK 6527
            SL   N     LR+L+L         + ++++  IKT    +W  VIPQL AR+     ++   + +LL  +        + +IYP  V S S      +  + I K + E+   LV++  +  +EL R+ +LW E+W   L +     + E N K                             ++++    ++ER        P+T +E+ F+  +  ++    +  +      N+++   AW            +   ++  ++ +   Q  SL+L  VSP L       + +PG  + +     + SI   + ++ +K +P+K   + +NG  + +L KG EDLR DERVMQ+ G+ NT+ +           I  Y V PL T +GLI  V    +L +L + ++ + K
Sbjct: 1862 SLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIG---RYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKG--------------------------MFAVLEPLHAMMERG-------PQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAW------------DLYYHVFRRIAKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKK 2227
[Close]
BLAST of SMG-1 vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1])

HSP 1 Score: 133.65 bits (335), Expect = 3.550e-30
Identity = 80/304 (26.32%), Postives = 138/304 (45.39%), Query Frame = 3 
Query: 6258 PKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCS--INSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            PK    + ++GK    L KG +DLR D  + Q+  + +T+  +  E    K +I  Y V P   R+G+++       +       Q            K  H                    RP D      R K+  A         ++   +  ++ F E+ ++  P       +C    ++   W    + +TRS A   I+G+ +GLGDRH+ N+L++    +++HID  V F++G  L  PE VPFRL+  I +  G   V G+FR  CE   E+++ SQ+ +LT++++ ++DP+ DW+
Sbjct: 2696 PKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQRNAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQ------------KGAHKR-----------------FRPQDWTSLACRKKMMEA---------QRMEFDKKLQAFTEVCQNFRPVF---RYFCMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDWT 2958
[Close]
BLAST of SMG-1 vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1])

HSP 1 Score: 133.65 bits (335), Expect = 3.820e-30
Identity = 80/304 (26.32%), Postives = 138/304 (45.39%), Query Frame = 3 
Query: 6258 PKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCS--INSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            PK    + ++GK    L KG +DLR D  + Q+  + +T+  +  E    K +I  Y V P   R+G+++       +       Q            K  H                    RP D      R K+  A         ++   +  ++ F E+ ++  P       +C    ++   W    + +TRS A   I+G+ +GLGDRH+ N+L++    +++HID  V F++G  L  PE VPFRL+  I +  G   V G+FR  CE   E+++ SQ+ +LT++++ ++DP+ DW+
Sbjct: 2670 PKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQRNAETRKRKLNIRRYKVVPFSQRSGVLEWCSGTVPIGEFLVDPQ------------KGAHKR-----------------FRPQDWTSLACRKKMMEA---------QRMEFDKKLQAFTEVCQNFRPVF---RYFCMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKILPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDWT 2932
[Close]
BLAST of SMG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010422.1 (pep scaffold:Pmarinus_7.0:GL478779:2292:46075:1 gene:ENSPMAG00000009431.1 transcript:ENSPMAT00000010422.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 251.136 bits (640), Expect = 2.173e-66
Identity = 168/546 (30.77%), Postives = 267/546 (48.90%), Query Frame = 3 
Query: 5160 LRQSILALDPEITSQMAEE----VVKIWLEFVTHHFSLHIAAAEAYFSFLK-DATPTKAKYSLC--------NKNKTT------ANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLV----------GSISENMNN---------------SSP-----------------------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKD--VILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNK----SLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDH 6542
            +R+ +LA  P +  +  E     ++ +W       F L+  +  AYF FL+ +A   +    L         N+ ++       A LR+L L+ K +  LR+ + + + T+P   W  +IPQLF+RL H +  +R  +  LL R+A  S +   L++YP +V          GS+   M+                S P                                   Y  I   L+ ++  +V +V + + ELRRITVLWDELW+  L Q      ++  QL+ E  ++ +   L+ ++   I++ K+ ++++  VF LE   + T+  PETP E WF + +   I++ +E +K+P N      +W   + L + +   +           R  +L L+L ++SP L+ +  + + LPG ++      + S+   +SILPTKTKPKK  FL+++G  Y+YL+KGLEDL LDER+MQ L I N MF K N  E +++H   Y VTPLG+R+GLIQ V+ AT LF LYKR Q R   T  H
Sbjct: 1651 VRRRLLAACPALADEDPETALDGLLSVWRAVAGRIFGLYKLSCRAYFIFLRLNAGQVRGDPHLILTSAAAPDNRQQSGDDLIVMATLRLLRLLVKHAAELREELEHGLATTPTSPWRGIIPQLFSRLNHPEAYVRQSICNLLCRVAQDSPH---LVLYPAIVGSVSLTGDAPGSVGGRMSALPSLLGSLNEREGGLSGPEGAASCSSQADGEGTEALPPLVGASSQDQAMMQDCYSKIVDKLMASSPTMVSQVQLLVSELRRITVLWDELWLGVLLQQQMMALRRVQQLEDEGKRVQANVTLRKEEKLAIMREKHTALMKPVVFALEHAHSITSASPETPHERWFQDTYGASISAALERLKNPPNPASPGASWAPFRQLLQSLQQRAQK---------RTSYL-LRLAEMSPRLSALAGTEMALPGESHAREAVCVHSLAPSVSILPTKTKPKKLSFLASDGNTYTYLFKGLEDLHLDERIMQFLSIVNNMFVKGNGREWHRFHARHYSVTPLGSRSGLIQWVDGATPLFGLYKRWQQRETLTAGH 2183

HSP 2 Score: 80.1073 bits (196), Expect = 1.177e-14
Identity = 30/71 (42.25%), Postives = 51/71 (71.83%), Query Frame = 3 
Query: 6951 NVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            +V   K  + +VPEKVPFR+T  I    G   V G+FR+SCE + +I+++ ++++LTL++ F++DP+VDW+
Sbjct: 2219 SVRVTKARAFEVPEKVPFRMTQDIERALGVTGVEGIFRLSCEQILQIMRRGRETLLTLLEAFVYDPLVDWT 2289

HSP 3 Score: 72.0182 bits (175), Expect = 3.632e-12
Identity = 58/252 (23.02%), Postives = 97/252 (38.49%), Query Frame = 3 
Query: 3291 DVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYV--RNHHDPERIKLSSEMRLLTRKTTSHSS-----------FILC-------------MEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWAR 3968
            + LEK+ YN YEGC     P  K+I TFF TN+  C +W  ++RL  + +   +GQ +  + HG  LL            +       E E  +++   A   L   + + G++            WI  +A    GR E A   ++E V      D     L   +  L   +TS +S            +L                  A+CY  L++   + +W+    + K ++    A K+ +N+ R
Sbjct:  917 EALEKLMYNAYEGCASALMPPPKAIRTFFFTNRQTCQDWLTRIRLAAMRVGLLAGQPAVTVRHGYHLL--------AEMKAGGTTQGGEFESAVMMVVEALRDLRCPDAITGMAVWCAGLAAKNLQWIGTVALHAEGRFEKAAMDYQEQVCLLTGVDCSIRGLDKALLRLANPSTSTTSPKHTTNGEGKKTVLTKPSEPPWEMVGYLASRTAECYMALSDWQAVQEWQTSAAALKPSTAAALALKVDMNYIR 1160
[Close]
BLAST of SMG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003429.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003429.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 150.599 bits (379), Expect = 5.196e-36
Identity = 115/385 (29.87%), Postives = 174/385 (45.19%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANT-MFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIV-NESTI---ISEEGHPIRPTD--------IYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSIL---TLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNS-SKSL---IDKRSVEFIINLNN 7277
            P PG N   ++     + +L +  KPKK     ++G+ Y  + K  +DLR D R+M+   + N  +  K  E       I TY V PL    GL++ V    SL ++                         DI+ NE  I   +SE    I P +        +Y  KL P                        VF+E    T PD  S            WY S + +TRS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG++  VPE VPFRLT  + +  GPM + GLFR +CE    ++   ++S++   +++  FI DP+V+WS  +     GS +     VN  +K +   I++R    I N NN
Sbjct: 2276 PFPG-NMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIV------------------------DILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPP--------------------VFHEWFLRTFPDPTS------------WYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQIVQDIEQRLHGVIKNPNN 2603
[Close]
BLAST of SMG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003412.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003412.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 150.214 bits (378), Expect = 7.240e-36
Identity = 115/385 (29.87%), Postives = 174/385 (45.19%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANT-MFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIV-NESTI---ISEEGHPIRPTD--------IYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSIL---TLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNS-SKSL---IDKRSVEFIINLNN 7277
            P PG N   ++     + +L +  KPKK     ++G+ Y  + K  +DLR D R+M+   + N  +  K  E       I TY V PL    GL++ V    SL ++                         DI+ NE  I   +SE    I P +        +Y  KL P                        VF+E    T PD  S            WY S + +TRS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG++  VPE VPFRLT  + +  GPM + GLFR +CE    ++   ++S++   +++  FI DP+V+WS  +     GS +     VN  +K +   I++R    I N NN
Sbjct: 2310 PFPG-NMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIV------------------------DILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPP--------------------VFHEWFLRTFPDPTS------------WYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQIVQDIEQRLHGVIKNPNN 2637
[Close]
BLAST of SMG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003421.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003421.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 150.214 bits (378), Expect = 7.794e-36
Identity = 115/385 (29.87%), Postives = 174/385 (45.19%), Query Frame = 3 
Query: 6183 PLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANT-MFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIV-NESTI---ISEEGHPIRPTD--------IYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSIL---TLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNS-SKSL---IDKRSVEFIINLNN 7277
            P PG N   ++     + +L +  KPKK     ++G+ Y  + K  +DLR D R+M+   + N  +  K  E       I TY V PL    GL++ V    SL ++                         DI+ NE  I   +SE    I P +        +Y  KL P                        VF+E    T PD  S            WY S + +TRS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG++  VPE VPFRLT  + +  GPM + GLFR +CE    ++   ++S++   +++  FI DP+V+WS  +     GS +     VN  +K +   I++R    I N NN
Sbjct: 2296 PFPG-NMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKDAESRRRDLRICTYAVIPLNEECGLVEWVNNTESLRTIV------------------------DILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPP--------------------VFHEWFLRTFPDPTS------------WYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTFGVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSRPLHGSWRGSANEAGEVVNEKAKQIVQDIEQRLHGVIKNPNN 2623
[Close]
BLAST of SMG-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007186.1 (pep scaffold:Pmarinus_7.0:GL476459:175296:202639:-1 gene:ENSPMAG00000006485.1 transcript:ENSPMAT00000007186.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 145.976 bits (367), Expect = 6.898e-35
Identity = 87/303 (28.71%), Postives = 145/303 (47.85%), Query Frame = 3 
Query: 6258 PKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAK-IDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            PK      ++G+ Y  L KG +DLR D  + Q+  + N + +   E  + K  I TY V PL  R+G+++       +        +  K+T  H K                         RP D  W    P +   K +++    R       L   + EL     P +     W   ++   W+   +++TRS A   I+G+ +GLGDRH+ N+L++ ++ +++HID  V F++G  L  PE VPFRLT  I +  G   V G+FR  CE   E+++ SQ+++LT++++ +FDP+ DW+
Sbjct:  736 PKIIDCEGSDGRTYRQLVKGRDDLRQDAVMQQVFHMCNELLAGSAETRTRKLSIRTYKVVPLSQRSGVLEWCVGTMPIGDY-----LVQKDTGAHTK------------------------YRPND--W----PSMHCRKFMNVAAQDRRN---GDLFLAYQELCHHFRP-VFRHFFWERFLDPAVWFERRLSYTRSVATSSIVGYIVGLGDRHVQNILIDLNSAELVHIDLGVAFEQGRILPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQEALLTIVEVLLFDPLFDWT 999
[Close]
BLAST of SMG-1 vs. Ensembl Yeast
Match: TOR2 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686])

HSP 1 Score: 203.756 bits (517), Expect = 2.355e-52
Identity = 171/634 (26.97%), Postives = 281/634 (44.32%), Query Frame = 3 
Query: 5442 GSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAW------KKIKTLQELILTESND---NIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGM---NNKSLLSIDKH---ISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYH--ITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNIL------------IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGV-SLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSV 7253
            G+W  V+PQL +R+   ++++   +  LL  L  +     + ++YP +V   SE+++       I + +  ++  LV++  +   EL R+ VLW E W       Y+ L+  + Q   E +                 K  + ++    +L+R        PET RE  F N F                 R+ NDA+      KK K +  L   ++ D   N+  K+ +   Q  +L+L  VSP L   +   + +PG      K ++ I K     S++ +K +P+KF    ++GK Y Y+ KG ED+R D  VMQ+ G+ NT+    N+ E  + H  I  YP  PL  ++GL+  V                N +TF  L                                   +R   EA KI + I   E W M  +            +EVF     +T    L K LW  S +S  W      +TRS AVM + G+ LGLGDRH  NL+++   G++IHID+  CF+  +   K PEKVPFRLT ++T       + G FRI+CENV ++++ ++ S++ +++ F FDP+++W   + +       G +  V ++  L+   ++
Sbjct: 1873 GTWLEVLPQLISRIHQPNQIVSRSLLSLLSDLGKAH---PQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQW-------YEGLDDASRQFFGEHNT---------------EKMFAALEPLYEMLKRG-------PETLREISFQNSFG----------------RDLNDAYEWLMNYKKSKDVSNL--NQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGGKPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQ--NDAECFRRHLDIQQYPAIPLSPKSGLLGWVP---------------NSDTFHVL-----------------------------------IREHREAKKIPLNI---EHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTKKIEEETGIQLPVMNANELLSNGAI 2401
[Close]
BLAST of SMG-1 vs. Ensembl Yeast
Match: TOR1 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827])

HSP 1 Score: 192.971 bits (489), Expect = 4.526e-49
Identity = 167/597 (27.97%), Postives = 261/597 (43.72%), Query Frame = 3 
Query: 5448 WTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQ--LQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESND---NIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPG--MNNKSLLSIDKH---ISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYH--ITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNIL------------IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGV-SLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            W  V+PQL +R+   D  + N +  LL  L  +     + ++YP  V   SE+++       I + +  ++  LV +  +   EL R+ VLW ELW       Y+ L   + Q  ++  I+K+ S  +  HK +                           P+T  E  F   F           +  N+  E+ + +KK K +  L   ++ D   N+  K+ R   Q  +L L  VSP L   +   + +PG     K  + I K     S++ +K +P+KF    ++GK Y Y+ KG ED+R D  VMQ+ G+ NT+    N+ E  K H  I  YP  PL  ++GL+  V                N +TF  L                                   +R   +A KI + I   E W M  +            IEVF     +T    L K LW  S +S  W      +TRS AVM + G+ LGLGDRH  NL+++   G++IHID+  CF+  +   K PEKVPFRLT ++T       + G FRI+CENV  +++ +++S++ +++ F  DP++ W 
Sbjct: 1872 WLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAH---PQALVYPLTVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELW-------YEGLEDASRQFFVEHNIEKMFSTLEPLHKHL------------------------GNEPQTLSEVSFQKSFG----------RDLNDAYEWLNNYKKSKDINNL--NQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFPGKPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLK--NDSECFKRHLDIQQYPAIPLSPKSGLLGWVP---------------NSDTFHVL-----------------------------------IREHRDAKKIPLNI---EHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWG 2367
[Close]
BLAST of SMG-1 vs. Ensembl Yeast
Match: TEL1 (Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene [Source:SGD;Acc:S000000184])

HSP 1 Score: 142.124 bits (357), Expect = 1.272e-33
Identity = 104/366 (28.42%), Postives = 169/366 (46.17%), Query Frame = 3 
Query: 6126 SLKLDDVSPG---LAKINSSLIPLPGMN------------NKSLLSIDKHISILPTK-TKPKKFRFLSTNGKHYSYLYKGL-EDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDH----LKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            +L+L ++  G   L ++N   +PLP  N               ++S+++ + I  T  + PK   F  ++G     L KG  +DLR D  + Q+    N +        +    I TY V PLG +AG+I+ V  +TSL  +  +    +K TFD     +K+    SN   +     I +E              ++P+L                 N   + F        PD L            +W+ +   +T+  A   I+G+ LGLGDRHL+N+L++ S G+ IHID  + FD+G  L +PE VPFRLT  I + FG   V+GLFR SCE VY ++++    ++ ++++  +DP+  W
Sbjct: 2387 TLRLANLKIGQYWLKQLNMEKLPLPTSNFTVKSSADGRKARPYIVSVNETVGITTTGLSLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQNDKVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSKLHTNDKITFDQARKGMKAVQTKSNEERLKAYLKITNE--------------IKPQLR----------------NFFFDSF--------PDPL------------DWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKLLPIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSW 2702
[Close]
BLAST of SMG-1 vs. Ensembl Yeast
Match: MEC1 (Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340])

HSP 1 Score: 112.079 bits (279), Expect = 1.582e-24
Identity = 79/303 (26.07%), Postives = 141/303 (46.53%), Query Frame = 3 
Query: 6255 KPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            KPK+   + ++G  Y  + K  ED+R D + MQ     + + SK          I  Y V  L    G+++MV    +L S+           ++ LK K                    + ++     WQ         K++  ++  +K+P  IL + F E      PD +            NW+ +   + RS AVM ++GH LGLGDRH +N+L++   G+++H+D++  F+KG  L VPE VPFRLT  + +  G +   G F+ S E    ++++++ +++ +++  ++D  +D S
Sbjct: 2061 KPKQLNIIGSDGNIYGIMCKK-EDVRQDNQYMQFATTMDFLLSKDIASRKRSLGINIYSVLSLREDCGILEMVPNVVTLRSILS-------TKYESLKIK--------------------YSLKSLHDRWQHTAVD---GKLEFYMEQVDKFP-PILYQWFLE----NFPDPI------------NWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLFEKGKRLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYDRNMDHS 2315
[Close]
BLAST of SMG-1 vs. Ensembl Yeast
Match: VPS34 (Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000004230])

HSP 1 Score: 58.5362 bits (140), Expect = 1.902e-8
Identity = 35/106 (33.02%), Postives = 52/106 (49.06%), Query Frame = 3 
Query: 6831 NFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVP--FRLTDIITNVFGPMAVNGL--FRISCENVYEIIQQSQDSILTLMDMF 7136
            NF +SCA  C++ + LG+GDRHLDNLLV   +G   H D+     +      P+  P   +L   I   FG    +    FR  C   Y I++++   IL L ++ 
Sbjct:  712 NFVKSCAGYCVITYILGVGDRHLDNLLVT-PDGHFFHADFGYILGQD-----PKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELM 811
[Close]
BLAST of SMG-1 vs. Ensembl Nematostella
Match: EDO48437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW4])

HSP 1 Score: 447.203 bits (1149), Expect = 4.942e-127
Identity = 274/824 (33.25%), Postives = 446/824 (54.13%), Query Frame = 3 
Query: 5217 VVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTK-----AKYSLCNK-NKT------TANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVG---SISENMN-------------------------------NSSP--------------------YHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDL--KHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNN-----KSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKL-EAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCK-------TIEEIKAAHNKKLQMIQY 7445
            ++ +W       F  +  AA+AYF +LK  +  +      KY +  K NK+      TA LR+L L+ K +  LR  +   +  +P   W ++IPQLF+RL H +  +R  +S+LL R+A+   +   LI+YP +VG   S+ + +N                               +S P                    Y  I   L   N +LV E+  FI+ELRRIT+LW+ELW+ SL Q + ++ ++  QL  EI +++S  +L    +  +++ K+ +I++  VF LE+ +  TN    TP E WFH  ++  I   +  + +P N  +   +W   K L + +   S       +K+  +   SL ++D+SP LAK+ S+ I +PG ++      S+ ++   ++ILPTKTKPKK  F+ ++G+ ++YL+KGLEDL LDER+MQ L I N MF++ + H    +    Y VTPLG R+GLIQ V+ A  +F+LYKR Q R   T   LKS A  SN                 ++P+++++ K+ P L E   +D     R++WP+ ++ +V  EL  +T  DLLS+ELWC S  +  W+  +  + RS AVM ++G+ +GLGDRHLDN+L++F+ G+++HIDYNVCF+KG  L+VPEKVPFR+T  +    G   V G+FR+SCE V +I++Q ++++LTL++ F++DP+VDW++  +S    +F GG  A + + S  +K+ +E  +  + F S    ++      ++ ++    NL EHL       +       T+E++KA      +M+Q+
Sbjct:   26 LLSVWKGVRDRLFKHYHYAAKAYFMYLKIGSQVRFLDSLPKYDVPQKINKSSDDGNVTATLRLLRLLVKHAGELRTVLEEGLAHTPTRPWKDIIPQLFSRLNHPETYVRQSVSDLLCRIAM---DAPHLIVYPAVVGSATSMPQFLNKKIKTEGIPYTAIFKEMCHELLEALGKPQRPSSQPDIPLADTTDKPEADNSMGACYRTIVSSLQSLNPKLVTELQGFIQELRRITLLWEELWLGSLIQTHQDVVRRQQQLDEEIKRVNSNVNLTDGQRAALIREKHVAIMRPIVFALEQLQKITNQQACTPHEQWFHRAYSALIEKALASLTNPANPSDARSSWDPFKQLLQTLQGRS-------MKKSAY---SLVMEDISPTLAKMKSTAIYMPGQSHFEGEIVSISAVVNEVNILPTKTKPKKLVFVGSDGQRHTYLFKGLEDLHLDERIMQFLSICNNMFTRADSHRCPLFCARHYSVTPLGPRSGLIQWVDGAVPVFALYKRWQQREAATNALLKS-AQGSNQPPPPP-----------MKPSELFYSKMTPALKEKGIVDPKESGRKEWPIAVMRQVLEELIAETPSDLLSRELWCSSTGALEWWHMTKTYARSTAVMSMIGYIIGLGDRHLDNMLIDFTTGEVVHIDYNVCFEKGRGLRVPEKVPFRMTPNLEMALGVTGVEGMFRLSCEQVLKILKQGRETLLTLLEAFVYDPLVDWTTANDSAFASAFYGGG-APSMTDSKENKKEMERGVTQSLFSSRVAEMKVSWTVNRDDMLNGLHNLLEHLEVYTGAVRHLKSMDLTLEQLKAQQ----EMLQH 819
[Close]
BLAST of SMG-1 vs. Ensembl Nematostella
Match: EDO44977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU99])

HSP 1 Score: 137.117 bits (344), Expect = 1.276e-31
Identity = 57/146 (39.04%), Postives = 100/146 (68.49%), Query Frame = 3 
Query: 6726 IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            +EVF     +T+ D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++   G+++HID+  CF+  ++  K PEK+PFRLT ++TN      ++G +R++CE+V   +++ +DS++ +++ F++DP+++W
Sbjct: 2213 VEVFEHALANTNGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYVLGLGDRHPSNLMLDRLTGRILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGIDGNYRLTCESVMRTMREHKDSVMAVLEAFVYDPLLNW 2358

HSP 2 Score: 117.857 bits (294), Expect = 7.032e-26
Identity = 98/410 (23.90%), Postives = 182/410 (44.39%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSLIGKRSR--SLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXX---XXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNK 6527
            +L + N     LR+L+L         + ++++  IKT    +W  VIPQL AR+    +++   + +LL  +     +  + +IYP  V S S +    +  + I K + E+++QLV++  +  +EL R+ +LW ELW   L     E   + +  +  +  + +  D  H+                 ++ER        P+T +E+ F+  +  ++          +   N+++   AW    T            +  ++ +   Q  SL+L  VSP L       + +PG          + ++   ++++ +K +P+K     +NG  + +L KG EDLR DERVMQ+ G+ NT+ +   E       I  Y V PL T +GLI  V    +L +L + ++ + K
Sbjct: 1822 ALSSGNSLQDTLRLLTLWFDYGHLPEVYEALVEGIKTIQIDTWLQVIPQLIARIDTPRQLVGRLIHQLLTDIG---KHHPQALIYPLTVASKSASSARHNAANQILKNMCEHSQQLVQQAVMVSEELIRVAILWHELWHEGL-----EEASRMYFGEGNVKGMFAVLDPLHQ-----------------MMERG-------PQTLKETSFNQAYGRDLMEAQEWCRRYQKSGNVKDLTQAWDLYYT------------VFRRISKQLPQLTSLELQYVSPKLLMSRDLELAVPGTYEPHKPVIHIRNVHSSLNVITSKQRPRKLCLAGSNGSDFMFLLKGHEDLRQDERVMQLFGLVNTLLASDPETSKRHLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKK 2187
[Close]
BLAST of SMG-1 vs. Ensembl Nematostella
Match: EDO29217 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T497])

HSP 1 Score: 119.783 bits (299), Expect = 5.772e-30
Identity = 49/120 (40.83%), Postives = 80/120 (66.67%), Query Frame = 3 
Query: 6801 NSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            N  +WY S + + R+ AVM ++G+ LGLGDRH +N+L + +NG+ +H+D N  F+KG +   PE+VPFRLT  + +  G +   G++R SCE    +++   DS+LT++  FI DP+++W
Sbjct:   16 NPTSWYESRLAYCRTTAVMSMVGYILGLGDRHGENILFDSTNGECVHVDLNCLFNKGETFDCPERVPFRLTHNLVDAMGLLGYEGVYRRSCEVTLRLMRSQCDSLLTVLGTFIHDPLMEW 135
[Close]
BLAST of SMG-1 vs. Ensembl Nematostella
Match: EDO36404 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIS1])

HSP 1 Score: 120.553 bits (301), Expect = 1.142e-26
Identity = 54/165 (32.73%), Postives = 97/165 (58.79%), Query Frame = 3 
Query: 6798 INSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSK-----SLIDKRSVEFIINLNN 7277
            ++   W+   + +TRSCA   I+G+ +GLGDRH+ N+LV+ ++ +++HID  V F++G  L  PE VPFRLT  + +  G   V G+FR  CE    +++ SQ++++T++++ ++DP+  W+   E          K A+ ++K     S I   +V+ + +L N
Sbjct: 1502 VDPAEWFERRLAYTRSCATSSIVGYIVGLGDRHVQNILVDCNSAELVHIDLGVAFEQGKVLPTPETVPFRLTRDLVDGMGVTGVEGVFRRCCEKTMAVMRTSQEALVTILEVLLYDPLYSWTLSPEK---------KMALQATKPDNDVSEISSTAVDLVGDLPN 1657
[Close]
BLAST of SMG-1 vs. Ensembl Nematostella
Match: EDO34280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPT8])

HSP 1 Score: 117.087 bits (292), Expect = 1.162e-25
Identity = 90/341 (26.39%), Postives = 151/341 (44.28%), Query Frame = 3 
Query: 6150 PGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNE---STIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVS-LKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            PG     S  +P   +N   +   D+ + +L +  KPK+      + + + +L KG ED+RLD+R+ Q+  + N + S+          + TY V P+  R GLI+ ++    L  L   H    ++    +  +    N  D+        IIS E +       + +K                + + P ++L   F +L    SP+               +     +F R+ A +CI  + LG+GDRHL N LV+   G +I ID+   F      L VPE VPFRLT   TN+  P+  +GL R +  +V   ++ + + +L  MD+F+ +P +DW
Sbjct: 1443 PGQYTGQSKPMPEYHVN---IAGFDEKVLVLASIRKPKRVTIRGDDERDHMFLVKGGEDIRLDQRIEQLFCMMNEVMSEDPACSQRNLRLRTYQVIPMTQRVGLIEWLKNTKPLKELL--HIAATESEKQAMVVRRKTKNMLDLTLRILFDIIISREANRTDTESEFKKK----------------QAQVPWDLLRRAFQQLA--ASPE--------------AYLTLRTHFARTHACICICQYVLGIGDRHLSNFLVDMRTGGLIGIDFGHSFGSATQFLPVPELVPFRLTRQFTNLLLPLKESGLVRNTMIHVMRALRGNHELLLNTMDVFVKEPSLDW 1746
[Close]
BLAST of SMG-1 vs. Ensembl Medaka
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974])

HSP 1 Score: 138.658 bits (348), Expect = 2.378e-32
Identity = 58/146 (39.73%), Postives = 101/146 (69.18%), Query Frame = 3 
Query: 6726 IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSL-KVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            +EVF     +T+ D L+K LW  S +S  W+    N+TRS AVM ++G+ LGLGDRH  NL+++  +G+++HID+  CF+  ++  K PEK+PFRLT ++TN      ++G +RI+C  V E++++ +DS++ +++ F++DP+++W
Sbjct:  472 VEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNW 617

HSP 2 Score: 113.235 bits (282), Expect = 2.430e-24
Identity = 97/414 (23.43%), Postives = 177/414 (42.75%), Query Frame = 3 
Query: 5328 SLCNKNKTTANLRILSLIGKRSR--SLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQC----YDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKS---PNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKS-----LLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNK 6527
            SL   N     LR+L+L         + ++++  IKT    +W  VIPQL AR+     ++   + +LL  +        + +IYP  V S S      +  + I K + E+   LV++  +  +EL R+ +LW E+W   L +     + E N K                             ++++    ++ER        P+T +E+ F+  +  ++    +  +      N+++   AW            +   ++  ++ +   Q  SL+L  VSP L       + +PG  + +     + SI   + ++ +K +P+K   + +NG  + +L KG EDLR DERVMQ+ G+ NT+ +           I  Y V PL T +GLI  V    +L +L + ++ + K
Sbjct:   81 SLSRGNNLQDTLRVLTLWFDYGHWPEVNEALVEGIKTIQIDTWLQVIPQLIARIDTPRALVGRLIHQLLTDIG---RYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHCNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKG--------------------------MFAVLEPLHAMMERG-------PQTLKETSFNQAYGRDLMEAQDWCRKYMRSGNVKDLTQAW------------DLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAASLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKK 446
[Close]
BLAST of SMG-1 vs. Ensembl Medaka
Match: atr (ATR serine/threonine kinase [Source:NCBI gene;Acc:101157099])

HSP 1 Score: 139.813 bits (351), Expect = 4.949e-32
Identity = 96/311 (30.87%), Postives = 146/311 (46.95%), Query Frame = 3 
Query: 6231 ISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWS 7163
            + IL +  KPKK     ++G+ Y+ + K  +DLR D R+M+   + N    K  E    + HI TY V PL    G+I+ V                N     H+ +K        +  E   +S  G  +R   +   K  P  E  +I   +      P      VF+E    T PD  S              RS+  + RS AVM ++G+ LGLGDRH +N+L +   G+ +H+D+N  F+KG +  VPE VPFRLT  + +  GPM   GLFR +CE    +++  ++ ++ L   F+ DP+V+WS
Sbjct: 1825 VEILASLQKPKKISLRGSDGRSYTMMCKPKDDLRKDCRLMEFNCLINKCLRKHAESRRRELHIRTYAVIPLNEECGIIEWVN---------------NTAGLRHILTK--------LYKERVYLS--GKELR--KLILPKTAPFEEKLRIHKEVLCARHPP------VFHEWFLRTFPDPTSS-------------RSA--YCRSTAVMSMVGYVLGLGDRHGENILFDSFTGECVHVDFNCLFNKGETFDVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMVL-KTFLHDPLVEWS 2086
[Close]
BLAST of SMG-1 vs. Ensembl Medaka
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:101171206])

HSP 1 Score: 83.9593 bits (206), Expect = 4.012e-15
Identity = 50/134 (37.31%), Postives = 69/134 (51.49%), Query Frame = 3 
Query: 6765 DLLSKELWCCSINSNNWYRS-SINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVS-LKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 7160
            DLL   L  C  NS   + S   +F  S A++C+    LG+GDRHL N +VN   G MI ID+   F      L VPE +PFRLT    N+  P+  +GL +    +     +   D +L  MD+FI +P +DW
Sbjct: 3716 DLLRSFLRMC--NSPEAFLSLRSHFISSHALLCVSHWILGIGDRHLSNFMVNVETGGMIGIDFGHAFGSATQFLPVPELMPFRLTQQFVNLMQPLKESGLIQSIMVHSLRAYRAEPDLLLNTMDVFIKEPCLDW 3847
[Close]
BLAST of SMG-1 vs. Ensembl Medaka
Match: ankef1a (ankyrin repeat and EF-hand domain containing 1 [Source:NCBI gene;Acc:101165612])

HSP 1 Score: 63.5438 bits (153), Expect = 4.328e-9
Identity = 35/99 (35.35%), Postives = 55/99 (55.56%), Query Frame = 3 
Query:  210 DGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASL 506
            D ++T+    +I A   G+ ++V++L+   ADVN      W PIH AA  GHV  V LLV  GA+VN ++    TP++ A++      V  L+  GA++
Sbjct:  519 DVQDTFFRTPMITACDSGSLEVVQYLLSKGADVNRGDQFFWTPIHHAAHAGHVEIVELLVKAGADVNAQSLDGGTPLVRAIECGQSLCVHFLVKAGANV 617
[Close]
BLAST of SMG-1 vs. Ensembl Medaka
Match: pik3cb (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:NCBI gene;Acc:101165660])

HSP 1 Score: 63.5438 bits (153), Expect = 4.416e-9
Identity = 43/127 (33.86%), Postives = 64/127 (50.39%), Query Frame = 3 
Query: 6786 WCCSINSNNWYRSSIN-FTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVC---FDKGVSLKVPEKVPFRLTDIITNVF-----GPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFI 7139
            W    NS +    +I  FT SCA  C+  + LG+GDRH DN++V  S GQ+ HID+      F     +K  E+VPF LT    +V      G     G FR  CE  Y +++++ +  +TL  + +
Sbjct:  862 WLKERNSGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVR-STGQLFHIDFGHILGNFKSKFGIKR-ERVPFILTHDFIHVIQQGKTGYTEKFGSFRQYCEEAYLVLRKNGNLFITLFALML 986
[Close]
BLAST of SMG-1 vs. Planmine SMEST
Match: SMESG000009788.1 (SMESG000009788.1)

HSP 1 Score: 7088.81 bits (18391), Expect = 0.000e+0
Identity = 3583/3589 (99.83%), Postives = 3585/3589 (99.89%), Query Frame = 3 
Query:   99 MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMXXXXXXXXIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNAXXXXXXXXXXXXXXXXILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDXXXXXXXXXXXXXXXXRITALKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECXXXXXXXXXXXXXXXXXXXXSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVEXXXXXXXXXXXXXXXDIVGKRSTXXXXXXXXXXXXXXXXXXXXSVAVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW 10865
            MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGK+YSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVEVELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITA KELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGL+KFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTD N EIIEKDEKDKKYNNNNSV VQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW
Sbjct:    1 MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKYYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVEVELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITACKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLIKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTDTNREIIEKDEKDKKYNNNNSVGVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW 3589

HSP 2 Score: 118.242 bits (295), Expect = 3.900e-32
Identity = 58/59 (98.31%), Postives = 58/59 (98.31%), Query Frame = 2 
Query: 10913 NFDSDIKPTPALFFRLEVFGIATYNNTNN-LFYLKLNQVTSSITPEIKIRCHTSFSSNM 11086
            NFDSDIKPTPALFFRLEVFGIATYNNTNN LFYLKLNQVTSSITPEIKIRCHTSFSSNM
Sbjct: 3590 NFDSDIKPTPALFFRLEVFGIATYNNTNNNLFYLKLNQVTSSITPEIKIRCHTSFSSNM 3648

HSP 3 Score: 42.743 bits (99), Expect = 3.900e-32
Identity = 33/33 (100.00%), Postives = 33/33 (100.00%), Query Frame = 1 
Query: 11155 SSPFNDFNLLFENXXXXXXXXXXXXXWMCRMWL 11253
            SSPFNDFNLLFENIVVLLICLLIGLLWMCRMWL
Sbjct: 3655 SSPFNDFNLLFENIVVLLICLLIGLLWMCRMWL 3687
[Close]
BLAST of SMG-1 vs. Planmine SMEST
Match: SMESG000009788.1 (SMESG000009788.1)

HSP 1 Score: 7017.17 bits (18205), Expect = 0.000e+0
Identity = 3548/3554 (99.83%), Postives = 3550/3554 (99.89%), Query Frame = 3 
Query:  204 MNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMXXXXXXXXIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAXXXXXXXXXXKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNAXXXXXXXXXXXXXXXXILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDXXXXXXXXXXXXXXXXRITALKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECXXXXXXXXXXXXXXXXXXXXSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVEXXXXXXXXXXXXXXXDIVGKRSTXXXXXXXXXXXXXXXXXXXXSVAVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW 10865
            MNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGK+YSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVEVELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITA KELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGL+KFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTD N EIIEKDEKDKKYNNNNSV VQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW
Sbjct:    1 MNDGRNTYQTNAIIEASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGGAEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQKDILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLNKAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKIMVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLMMSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECSTEGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVIDRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLSNLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKISDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLLQPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTNYYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDNNLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLVQSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKYLLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLSFAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIVVSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYFDLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDSTDKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQKLKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTPEDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVCIEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKILVPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTIGRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIADCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKWDENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFIVKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNFSTTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISHSFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLTSSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAKISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILASKSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSETICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEITSQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNKTTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDKMIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVLVENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSEIDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESWFHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKYYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFITIEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYLRGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFFNKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEIIQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITENLLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVEVELQEELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMANITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSMNMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQLTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVPMKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMGSSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHCKSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKMFCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFYNQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSLCWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITACKELLSKLDTISSKFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNIDRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIKLKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEARGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDIKSKVDRVLKIMSLFEKFNFTMDGLIKFLLKGGDGEISIYEYIGQLHYQINNLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMAEINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRSTDTNREIIEKDEKDKKYNNNNSVGVQKAIEVWKLTETRLNSANQKQPLASNEYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAW 3554

HSP 2 Score: 118.242 bits (295), Expect = 3.622e-32
Identity = 58/59 (98.31%), Postives = 58/59 (98.31%), Query Frame = 2 
Query: 10913 NFDSDIKPTPALFFRLEVFGIATYNNTNN-LFYLKLNQVTSSITPEIKIRCHTSFSSNM 11086
            NFDSDIKPTPALFFRLEVFGIATYNNTNN LFYLKLNQVTSSITPEIKIRCHTSFSSNM
Sbjct: 3555 NFDSDIKPTPALFFRLEVFGIATYNNTNNNLFYLKLNQVTSSITPEIKIRCHTSFSSNM 3613

HSP 3 Score: 42.743 bits (99), Expect = 3.622e-32
Identity = 33/33 (100.00%), Postives = 33/33 (100.00%), Query Frame = 1 
Query: 11155 SSPFNDFNLLFENXXXXXXXXXXXXXWMCRMWL 11253
            SSPFNDFNLLFENIVVLLICLLIGLLWMCRMWL
Sbjct: 3620 SSPFNDFNLLFENIVVLLICLLIGLLWMCRMWL 3652
[Close]
BLAST of SMG-1 vs. Planmine SMEST
Match: SMESG000018015.1 (SMESG000018015.1)

HSP 1 Score: 157.532 bits (397), Expect = 1.050e-37
Identity = 115/389 (29.56%), Postives = 179/389 (46.02%), Query Frame = 3 
Query: 6006 NNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSL----KLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAV-NGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVD 7157
            N +RE  D  +      +L L +   +    LK G +  + L    +L    P  A    S +P P      +  +++   +LP+ TKPKK  ++ T+GK Y  + K  +DLR D R+M++ G+ N +  + +E      +I TY VTPLG ++GLI+ V                               NN +   +  +   + H  R   I WQKL  +          DS EK  M    EV         P + +K         N WYRS   + RS AVM ++G+ LGLGDRH++N+L + ++G ++HIDYN  F+ G +L+ PE VPFRLT  + +  GP    NGLFR SC     +++   + I+ +     +D + +
Sbjct:  959 NALREIGDVEESFFVKMQLNLKKCGKSFDHLLKPGIYSGVILPLYHQLFGTLPTPATFKDSYLPFPS-KLVCISHMEESADVLPSLTKPKKMIWIGTDGKKYIMIVKPKDDLRRDCRIMELNGMFNRLMRRNSETRHRLLYIRTYAVTPLGEKSGLIEWV-------------------------------NNTESFRQVVV---DLHIQRNNPIIWQKLHARYAQRG-----DSFEKKLMKFTKEVL-----PLYPVVFNKWFLQKFPEPNAWYRSVQKYCRSVAVMSMVGYILGLGDRHIENILFDHTSGDVVHIDYNCLFNHGKTLEWPEVVPFRLTRNMQDGLGPCGENNGLFRSSCVATLNLLRNEIEPIMAVFKPMYYDTLTE 1302
[Close]
BLAST of SMG-1 vs. Planmine SMEST
Match: SMESG000025384.1 (SMESG000025384.1)

HSP 1 Score: 157.918 bits (398), Expect = 1.110e-37
Identity = 111/406 (27.34%), Postives = 195/406 (48.03%), Query Frame = 3 
Query: 6126 SLKLDDVSPGLAKINSSLIPLPGM--NNKSLL---SIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNIL--IEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKG-VSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDWSSGIESGHYGSFDGGKYAVNSSKSL---ID-----KRSVEFIINLNNFQSVFI 7295
            +L+L   SP L   N  ++ +PG    N+ ++   SI   ++++ +K  P+K   +  +G +Y +L KG ED+R DER MQ  G+ NT+     +       I    V PL T  GLI  V  + +L ++ + ++ + +                       +++ E   +        K+ P  E               +NI+   EVF    R++    L+  LW  S NS  W+    NF RS AVM ++G+ LGLGDRH  N+++   +G++IHID+  CF+   +  K PEKVPFRLT ++        + GLFR +   +  +++++++S+L +++ F+ DP++ W       H  +  GG+  V +  SL   ID     +++++  +N NN  +  +
Sbjct: 2345 TLELSVASPRLHDYNDWILAIPGSYDPNRPIVKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRINLSIQRMSVIPLSTNTGLIGWVPNSDTLNAVIRDYREKTQ----------------------VLLNREHKEML-------KIAPDFEK--------------LNIIQKTEVFESGIRESDGKDLAHILWLKSHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQWVL-----HDNTKKGGENTVETDDSLSANIDAINELRKALQLHVNPNNVPTTSV 2702
[Close]
BLAST of SMG-1 vs. Planmine SMEST
Match: SMESG000018015.1 (SMESG000018015.1)

HSP 1 Score: 157.532 bits (397), Expect = 1.136e-37
Identity = 115/389 (29.56%), Postives = 179/389 (46.02%), Query Frame = 3 
Query: 6006 NNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSL----KLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPTKTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKVPFRLTDIITNVFGPMAV-NGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVD 7157
            N +RE  D  +      +L L +   +    LK G +  + L    +L    P  A    S +P P      +  +++   +LP+ TKPKK  ++ T+GK Y  + K  +DLR D R+M++ G+ N +  + +E      +I TY VTPLG ++GLI+ V                               NN +   +  +   + H  R   I WQKL  +          DS EK  M    EV         P + +K         N WYRS   + RS AVM ++G+ LGLGDRH++N+L + ++G ++HIDYN  F+ G +L+ PE VPFRLT  + +  GP    NGLFR SC     +++   + I+ +     +D + +
Sbjct:  973 NALREIGDVEESFFVKMQLNLKKCGKSFDHLLKPGIYSGVILPLYHQLFGTLPTPATFKDSYLPFPS-KLVCISHMEESADVLPSLTKPKKMIWIGTDGKKYIMIVKPKDDLRRDCRIMELNGMFNRLMRRNSETRHRLLYIRTYAVTPLGEKSGLIEWV-------------------------------NNTESFRQVVV---DLHIQRNNPIIWQKLHARYAQRG-----DSFEKKLMKFTKEVL-----PLYPVVFNKWFLQKFPEPNAWYRSVQKYCRSVAVMSMVGYILGLGDRHIENILFDHTSGDVVHIDYNCLFNHGKTLEWPEVVPFRLTRNMQDGLGPCGENNGLFRSSCVATLNLLRNEIEPIMAVFKPMYYDTLTE 1316
The following BLAST results are available for this feature:
BLAST of SMG-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SMG11.348e-13530.69SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
SMG11.422e-13530.69SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
ATR1.947e-3727.35ATR serine/threonine kinase [Source:HGNC Symbol;Ac... [more]
ATR2.188e-3727.35ATR serine/threonine kinase [Source:HGNC Symbol;Ac... [more]
ATR3.889e-3729.04ATR serine/threonine kinase [Source:HGNC Symbol;Ac... [more]
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BLAST of SMG-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smg-14.029e-9330.36Serine/threonine-protein kinase smg-1 [Source:Uni... [more]
let-3636.356e-4825.47Target of rapamycin homolog [Source:UniProtKB/Swi... [more]
let-3636.515e-4825.47Target of rapamycin homolog [Source:UniProtKB/Swi... [more]
smg-11.962e-3928.63Serine/threonine-protein kinase smg-1 [Source:Uni... [more]
atl-12.996e-2627.05Serine/threonine-protein kinase ATR [Source:UniPr... [more]
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BLAST of SMG-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nonC1.447e-10832.42gene:FBgn0263968 transcript:FBtr0070972[more]
nonC1.447e-10832.42gene:FBgn0263968 transcript:FBtr0343321[more]
Tor1.354e-5226.16gene:FBgn0021796 transcript:FBtr0080422[more]
Tor1.355e-5226.16gene:FBgn0021796 transcript:FBtr0336615[more]
mei-411.372e-2827.51gene:FBgn0004367 transcript:FBtr0074271[more]
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BLAST of SMG-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smg12.415e-13730.43SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
smg19.499e-13730.71SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
smg11.195e-13630.71SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
atr1.203e-3628.35ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-G... [more]
AL844179.12.153e-3239.73pep chromosome:GRCz11:CHR_ALT_CTG8_1_27:46082265:4... [more]
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BLAST of SMG-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SMG12.350e-13433.56SMG1 phosphatidylinositol 3-kinase-related kinase ... [more]
SMG14.220e-13433.56SMG1 phosphatidylinositol 3-kinase-related kinase ... [more]
SMG14.243e-13433.56SMG1 phosphatidylinositol 3-kinase-related kinase ... [more]
SMG14.315e-13433.56SMG1 phosphatidylinositol 3-kinase-related kinase ... [more]
SMG14.736e-13433.56SMG1 phosphatidylinositol 3-kinase-related kinase ... [more]
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BLAST of SMG-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Smg12.448e-13630.77SMG1 homolog, phosphatidylinositol 3-kinase-relate... [more]
Atr7.940e-3827.27ataxia telangiectasia and Rad3 related [Source:MGI... [more]
Atr8.343e-3827.27ataxia telangiectasia and Rad3 related [Source:MGI... [more]
Atm4.025e-3228.99ataxia telangiectasia mutated [Source:MGI Symbol;A... [more]
Atm4.060e-3228.99ataxia telangiectasia mutated [Source:MGI Symbol;A... [more]
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BLAST of SMG-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8BKX6|SMG1_MOUSE1.712e-13530.77Serine/threonine-protein kinase SMG1 OS=Mus muscul... [more]
sp|Q96Q15|SMG1_HUMAN6.829e-13530.69Serine/threonine-protein kinase SMG1 OS=Homo sapie... [more]
sp|Q70PP2|SMG1_DROME1.451e-10732.42Serine/threonine-protein kinase Smg1 OS=Drosophila... [more]
sp|Q61CW2|SMG1_CAEBR1.004e-9331.64Serine/threonine-protein kinase smg-1 OS=Caenorhab... [more]
sp|O01510|SMG1_CAEEL5.124e-9230.36Serine/threonine-protein kinase smg-1 OS=Caenorhab... [more]
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BLAST of SMG-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H9XVZ74.417e-1499.88SMG-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A5N4AFW01.604e-14527.46Uncharacterized protein OS=Photinus pyralis OX=705... [more]
A0A1Y1N0668.430e-14527.40Uncharacterized protein (Fragment) OS=Photinus pyr... [more]
A0A267EA244.662e-14031.74Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267GHW85.615e-14030.53Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of SMG-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
smg12.385e-13730.96SMG1 nonsense mediated mRNA decay associated PI3K ... [more]
atr3.066e-3529.06ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-G... [more]
mtor8.440e-3239.73mechanistic target of rapamycin kinase [Source:NCB... [more]
atm3.550e-3026.32ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-G... [more]
atm3.820e-3026.32ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of SMG-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000010422.12.173e-6630.77pep scaffold:Pmarinus_7.0:GL478779:2292:46075:1 ge... [more]
ENSPMAT00000003429.15.196e-3629.87pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-... [more]
ENSPMAT00000003412.17.240e-3629.87pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-... [more]
ENSPMAT00000003421.17.794e-3629.87pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-... [more]
ENSPMAT00000007186.16.898e-3528.71pep scaffold:Pmarinus_7.0:GL476459:175296:202639:-... [more]
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BLAST of SMG-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TOR22.355e-5226.97PIK-related protein kinase and rapamycin target; s... [more]
TOR14.526e-4927.97PIK-related protein kinase and rapamycin target; s... [more]
TEL11.272e-3328.42Protein kinase primarily involved in telomere leng... [more]
MEC11.582e-2426.07Genome integrity checkpoint protein and PI kinase ... [more]
VPS341.902e-833.02Phosphatidylinositol (PI) 3-kinase that synthesize... [more]
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BLAST of SMG-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO484374.942e-12733.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO449771.276e-3139.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO292175.772e-3040.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO364041.142e-2632.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO342801.162e-2526.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMG-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtor2.378e-3239.73mechanistic target of rapamycin kinase [Source:ZFI... [more]
atr4.949e-3230.87ATR serine/threonine kinase [Source:NCBI gene;Acc:... [more]
prkdc4.012e-1537.31protein kinase, DNA-activated, catalytic subunit [... [more]
ankef1a4.328e-935.35ankyrin repeat and EF-hand domain containing 1 [So... [more]
pik3cb4.416e-933.86phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
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BLAST of SMG-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009788.13.900e-3299.83SMESG000009788.1[more]
SMESG000009788.13.622e-3299.83SMESG000009788.1[more]
SMESG000018015.11.050e-3729.56SMESG000018015.1[more]
SMESG000025384.11.110e-3727.34SMESG000025384.1[more]
SMESG000018015.11.136e-3729.56SMESG000018015.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30001428
GenBankAFH08796.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001428 ID=SMED30001428|Name=SMG-1|organism=Schmidtea mediterranea sexual|type=transcript|length=11368bp
TGGGTAAATACGTATTTTGCAATGAATATAGTATTCCTTTATTCATTTGA
TGTTTATAAAAATGAACTGTGTCAATCATTTATAATATAAATTTAGAAAT
GGATTTATTCGACTCTTGGTTTGAATCAATCCGAAATGGTAACTTGAAAG
AAATTATTAATATTTTTAAAACCAACCCTGATTTTATTAATAAATTTACT
ACTATGAATGATGGTAGAAATACTTATCAAACTAACGCAATTATTGAAGC
TTCATTTCAAGGAAATCGAGATCTTGTGAAATGGTTGATAGAGAACAATG
CAGATGTTAATTCTATGTCCGATGGTGGCTGGCGTCCGATACATTTTGCA
GCTCAACACGGTCATGTGACCACTGTTAATTTGTTGGTACTTGGAGGTGC
TGAAGTAAATGTAGAAACAGAAGCTAAAGAAACTCCAATTTTATTTGCAC
TTCAAGCCTATATGCGAGATACAGTTAAAAAATTATTACACCATGGGGCA
TCTTTAGTTGGAATTGATAGGAACTATCTACAAATGTGTATACAAAAAGA
TATATTAGATCCAGCATTTCTAGATGAGCAGAACAAAGCATATTTAGTAG
ATACGAGTAGTTATAGAAAAATTGACAGTAATGGTTTCGATATCATGAGT
CGACAGCATGATCGTGAAATCGAAGAAATAAAACCTGTTAAGCTTAACAA
AGCAAAAATTATCACAGAATACGATAATGAATTAAAACGTCGAAGGCAGG
ATCTATTAAAGAAGATGCGACGAACCGCTGAACCAGTTAATACTCTGGGA
CCATTAATTAGAAAATTATCACAGTCTGAAAACGATTCAGAAAAGATAAT
GGTTGTTAAAGAACTCATTATGATTTGCAATCAAGATGGCGGAGTACCTC
AGAATAAATTTTCAGATCAAATGATAAACATTTTGGAATTATGCATATGC
GACTCTTCATCATCTGATGAATTTATTGTTCTATCAGGAAAACTAATGAT
GAGTTTGTTACACTTAAATATTAGACGTGGCGATGCGGCAATTGTGGATT
TTTGGTGTCGGATTTTCGATAAAATGACTAATTTGCAAATTGAGCAATAT
ACTCAACAAATTCTCAAAATGCTGCTCAAAATGATTGAATGTTCCACAGA
AGGTGTAATCAATAATTTAAAATCAAACAAAGATACATTTTTAAAAAATT
GGGAATACTTTTTTGAAAATCTATGTTTTCCAAAATGCTTGAATTTATCG
TTAATGATTTTAAAGAGTGTTTTCAATCACTGTCCAGATGTGGTTATCGA
TCGATTTCACAATGTTATCGATATAATGATCGGATGGTGTATTCATCCGG
ACACAGATCTAGTGACAATGGAAGCTCTTTGTCAACGTAGTGTAGACTTG
CACGAATGCTGGATTTCGGACACTATCAATCTAAAAAAGACTCTTAGTAA
TCTCCAGAAAGACTTTTTAACCCATTGTCAAATGTTGTCAAGAATTCATC
GTATTGATAAAGATCGTTCTCAAATCGATGATTTAAAATTAAAAATCAAA
TTCTTCTGCTTTGCATTATCATGTGTTACCGCTGGAGTGAGCAAAATTTC
AGATTTGAATGACGTTAACTTCCACGAAAATAGCTCGGAAAATCTTACTG
AGATATTGTCAAATGTATACATCATTGGCATAATTGAGAAAATAACCGAA
GGATTGATCATGTGTAGCAAACAAATAGATTTCGATAATCTGTTATTACA
ACCCAATTCGGTGATACTTCACCTGTTGTTCATTTTAAACAAAAAGGAAC
CGATCGGAACCGTATATCAAAGTGTATTTCGATACGTGCTCGGTACTACA
TTGCCACTGCAATCACATATTTTGTCAGAGGGCAGTAATAACACAAATTA
TTACAATAAACAATTAATTATTTCCTATCTCGATCTAATCAGCATTTGCT
TAGTGAATATCAACCTGGAACCCGCAACAGTTGTTCAAATTCTCTCTCCG
GTTAACTGGATACACTCGTGCATTTTCTACGGCTCGTTTATCGATAACAA
TCTAATGCAAAAGTATTTGCGATTGGTGGATATTATCGCCAAATCCCATT
GCGTAACTACATTCTATCAAATTCTTTTAAGTGATCTGGAATTGGCACTC
AATATTTTAATGAAAATATCCAATTGTACAAATATGGTGCGTTTAGTCCA
GAGTAATGCGTTCAAAGCCAAATCATATGAAACACCACAGGCTGAACTGG
TAGTCAAATACAATATCAATCTGATAATTATGCTCTATAATCGATTAAGT
GATCCTTCGATTTTAGTTCCATCGATTCCAGTACTGTTTACCAAGTACTT
GCTGTTCACAGAATCCAATATCATCGTTAAATATCCAAATATTGCAAGCT
TTTTAATTAGCACAATATCCAAGATTAAACTCTCTCACGATTTGATTCCT
GATTGGATAAAATTTCTCTGTTTGATAATTAATACTGGCAATTTAAGTTT
TGCAATAAAAAGTATGGGATTCGAAATTCTGAAAACTGTTTTGGCAACTA
ATAAATCAATTTTAGAAAATAGTACTGAATTAATTAATCTATTAGTTAGT
AGTGTTTGTAATTTGATGAGTTCAGAAAGTGAAAAAGAGTCAATAGTAGT
TAGCTGTCTCAATATCATTGTTGACAATCTCAATTCTTATCAGACATTAA
TTAATGAAACCAACATAGACAATCTTGTAGCTGTTAATATAATTTTCAGC
ATGCATTCATCGCATTTGGTTCGTAGTAAATCCATTAAAATATACTTTGA
TCTTATTACAAAAACCGATTCACCTATTTCCCGAAAATTATTCCATAAAA
ACTTAAAGTCAATTCAAGCTATTTCGATATCTGGTCGATCTTTCAAATTT
CCTATAGACTTCAGCAAGTCTATTTTCAATTGGATAATTGATTCGACAGA
CAAATACAGCTTCGAAAGCAGGGATATCCAGCGATTACACAGCATTGTGG
CAATCAACCAAAGCAAACTCGAGCATTTATTTTGCAATCGAATGATAATG
GTTTATGAGATAATCATCAATGCTTGTTGGGATTGTGTGCGACAAAAGTT
GAAATTTGATCAGAATGCTGATTCAAGAATCACTTTGATGACTATTGAAA
ATATGGTAAAATCAATATTGACCAATGGAAATTCTCTTAAAGCTATAACC
GATAAACGGTTTAGAAAATTGATGACTAAATTTACCAGTAAAACTCCAGA
AGACCAATCGTTATCAGTTAATTTAATGATTCTTTTATTGGATGTCCTGG
AGAAAATGTTTTATAATTGCTATGAAGGATGTTGTCTTGGATTCCCCCCA
GTTAATAAATCGATAGAAACTTTTTTTGTGACCAACAAAAACGTTTGCAT
TGAATGGTTCATTAAAATGCGATTATTAATTGTTGCTTTGGCTCAATATT
CCGGCCAGTGGAGCACTGTTATTTGGCATGGAATGCAATTATTGAAATTT
CATTTGGATAAATGCAATACACACTCTAGCTCAGCAGCAAAAATTCTCGT
ACCGGAAGTTGAGGACTGTATAGTGCTAACGTCTATGGCTTATAGTAAAT
TGGGAAATTGGGAAAACTTATATGGATTAAGTCAATTATCAGTGGAAACT
TATGGCAGTAAATTTGATTGGATTGAAGCTCTTGCCGATAAGACGATTGG
ACGATTAGAAATGGCTTTATCAAAATTTGAAGAATATGTCAGAAATCATC
ACGACCCAGAAAGGATTAAATTGTCTTCGGAAATGAGGTTATTGACAAGG
AAAACCACAAGCCATAGTTCGTTTATTTTATGCATGGAAGAAATAGCTGA
TTGTTATAAATTATTGAATAACCCAGATGGATTGGACCAGTGGAAAAAAC
AAATCCAATCGTGGAAGTCAAATTCACAAATACAAGAAGCTCAAAAATTG
AGTATTAATTGGGCAAGACTTGTCTGTCTGACAAAATTATCGAAATGGGA
CGAAAATATGGATGATAAATGCATTCCATTAAGGGCAAACGAGTTATCTT
GGAAATATCGATCTGTTATCGATAATTGTGAAGATAGTTTGTTTCTCTCT
GTCGTTGAAAAATCTTCTTGTAAAGAAGTGGAAATAGAAAGTTTTATTGT
GAAATTATCATCGATTCAATCGATTTGTGATTTCCCGAATACATTTACCA
ATCCGGATATCATTTTAATCAATGAAAGATTGAAACTTTTAAAAGCAGCC
AATAAAGGAGAAAGTTTTATTGTTGACTGCAAAAATCTGTCAAATTTTTC
AACAACTTTACCACTGCCTGTTATAAGCTTCTGTAATACAATCCAAAAAC
GATATAACATCCCACAGTGTTTTCCTAATCAAAAATTCTTAATTAAATGG
CACAGAAATCATCTTAATTTTAATAAATGTCATAGTTTGATTTCACATTC
TTTCACCTCATTCCTCGGTAAAGAAATTAACCAGCAATCTAATCTAAGCA
ATTCCCAATTGCCCATAATTCAAATGCAAATCGAAAGAGAACTTGTAAAA
CTGTTATGGGAAGAAGACAAAAAGAAAGATTCTCTTCAATTATTGACCAG
TAGCCTAAAGGATAGTTTGTTGTTTGAAACAAGTGATTCCACTTTGCACA
GTTCTAAGTGTCAATTAAATACAAAATCTCTATTAACGTTGTTTATGTGG
CTATGTAATGAAAAATCGAAATTTCCGAAATTTTGTAATGATGCTAAAAT
TTCTAGTAATCTCCAATTTCTCATTGAACTAGCTGAAGTTCCATGGATAA
ACGGTTTACCATTAGTTTCACCCCAACATCGATCAATGGAGAAAACTTGT
CAATCATCTGTGACAGATGTTTGTAGTCAATTACTCATTCTCGCCAGCAA
GTCGCGTAACCAAGACAACAGTGATAAAAGTTTTATGGCATTAGCCCAAT
GGTGTCTCAGCAGATCACGATCATTGGATGAAATTGGATTTAACGCAGAA
ACGATAGATTTGGCAACAAAATTAGAAAACCAAGGCTTTTCGAGTGAAAC
TATATGCAACATTGAGTTACTTTTAAAGAGTAATTTTTGTCCATCACAAA
TGAAAACCGAAAGCGATTGGTTTGGAGACTGTTATGAAGATTCAGGATTT
TTAGTTGAATTAAGACAATCGATTTTAGCTCTTGATCCTGAGATTACATC
TCAAATGGCGGAAGAAGTCGTTAAAATATGGCTGGAATTTGTTACGCATC
ACTTTTCTCTTCATATCGCAGCTGCAGAAGCATATTTTTCTTTTTTGAAA
GATGCAACTCCAACGAAAGCCAAGTATAGCTTGTGTAATAAAAATAAAAC
CACAGCGAATTTAAGAATATTATCTTTAATCGGAAAACGATCGAGATCTT
TGAGAGATTCAATAATCAATAAAATAAAAACCAGTCCTCCTGGTTCATGG
ACTAATGTAATTCCACAATTGTTTGCTCGGTTGAAGCACAGTGATAAAAT
GATCAGGAACTGTATGTCAGAACTGTTGCAAAGATTGGCAATTTCCAGCA
ACAACTGTAGCAAATTGATTATTTATCCTACACTAGTCGGTTCTATCAGT
GAAAATATGAATAACAGCTCGCCATATCACGATATAAAGAAAGTTCTTGT
TGAGAATAACAGACAACTAGTCGAGGAAGTCGGTGTGTTTATCAAAGAAT
TACGACGTATCACTGTTTTATGGGATGAGCTATGGGTTTCATCACTGGGA
CAATGCTACGATGAACTTAATAAAAAAGCTCATCAATTGCAATCAGAAAT
AGATAAGATTGATTCTCAAGATGATTTGAAACATAAAGATGTCATTTTGA
AACTTAAGTACAATTCAATTATTCAAGCCGCAGTTTTTATTCTTGAACGA
ACCAAAAATGCGACAAACATGATTCCAGAAACTCCAAGAGAATCTTGGTT
TCATAATATGTTTGCAGAGGAAATTACAAGTACAATTGAAGAGATTAAAA
GTCCAAATAATATTCGAGAATTTAATGATGCGTGGAAAAAAATCAAAACT
CTTCAAGAGTTGATACTTACTGAATCTAATGATAATATAAAAGTAAAACT
AAAACGAGGAAGACATCAATTTCTATCTTTGAAATTAGATGATGTTAGTC
CAGGCTTAGCTAAAATCAATTCAAGCCTAATTCCTTTGCCTGGCATGAAC
AATAAATCATTGCTTTCAATAGATAAACATATTAGTATATTACCAACAAA
AACTAAACCGAAAAAATTTCGATTTCTATCAACAAATGGCAAGCATTATA
GTTATCTTTACAAAGGACTGGAAGACTTGAGATTAGATGAGAGAGTAATG
CAGATTTTAGGAATAGCCAATACAATGTTTAGCAAAATCAATGAACACGA
ATCAAACAAATATCACATTACTACATATCCAGTGACGCCTTTGGGTACAC
GTGCAGGTTTAATACAAATGGTTGAGGAAGCAACATCTTTATTTTCTTTA
TATAAGCGTCATCAAATGCGTAATAAAAATACATTTGATCATTTGAAATC
GAAAGCTTGTCATTCCAACAATGGAGATATCGTTAATGAGTCCACGATAA
TATCGGAAGAGGGTCATCCTATCAGACCAACAGATATTTATTGGCAAAAA
CTTAGACCGAAACTAGAAGCAGCAAAAATCGACATTGGAATTGACAGCCG
TGAAAAATGGCCTATGAATATTTTAATAGAAGTGTTTAATGAATTAAATA
GGGATACGTCTCCTGATTTGCTTTCGAAAGAATTATGGTGCTGTAGTATC
AACTCTAATAATTGGTACAGGAGTTCGATAAATTTCACCAGATCATGTGC
TGTAATGTGTATTATGGGACATTGTCTTGGATTAGGCGATCGGCATTTGG
ATAATTTGCTGGTTAATTTTTCCAATGGACAAATGATTCATATTGACTAC
AATGTTTGCTTTGATAAAGGTGTTTCTCTGAAGGTTCCTGAAAAAGTTCC
GTTCCGTCTTACTGATATAATCACAAATGTATTCGGTCCAATGGCTGTCA
ACGGACTTTTCAGAATATCATGTGAAAATGTCTATGAAATTATTCAGCAA
TCCCAAGATAGTATTCTAACATTAATGGATATGTTTATATTTGACCCAAT
TGTCGATTGGTCTTCCGGGATAGAGTCAGGTCATTATGGTTCATTTGATG
GAGGAAAATACGCTGTCAACTCGAGTAAAAGTCTCATTGATAAACGTTCA
GTAGAATTTATTATAAATCTTAATAACTTCCAATCAGTTTTCATTACAAT
TGAAGACGATTTGAAAAGTTGCCAGGAGAAATTAATTCTCGATTTCCGAA
ATTTACACGAACATTTGAATAGAAGTTGGTCAACTTGTAAAACAATTGAA
GAAATAAAAGCCGCTCACAATAAAAAGCTGCAAATGATTCAATATTTGCG
TGGATATGAAACGAATAACGAATGTAAAATCGTAGAACAATTCAATTACG
TGCGAAAACTAGAAGAACGTTCCATGCATTTAGAATTAGACATTCAAAAG
CGACAACAGCAACTGAAACTTGTTAGTATGGAACACAGTGCATTTTTCAA
TAAAATACTTTCAGCTGCAGATTTTATCAGTTTAAAACTCGATATTAAGA
ACATCAAAAATTTCTTTGAGGAACACATAGAAAATATCGAAAAATCAATA
ACTGTGTTTTGTGATCAATATAGCGTCACAAATCCATACGGGGAAATTAT
CCAAGAACTTCTATTTATGCTTGATAACATGGAAGAGATTCAAAATGGTT
TGATAGTTTTGGAAAAATATCGAAATATTATCCAAGAAATGCCCCAGTCA
TATTACAATTCCGATCGATGCAGTTATATGTTGCAAATCACAGAAAATCT
TTTAAAAACTCCATCATTATCAAATATTCAAAGAAATTTCCAAAACTATT
CCGATTGGATGATCAAAGACGATCAGAGTTCAATTGAAAAATTTACCAAT
GAAAAAAATAATTGGAATGCTTTATTGAAAGTCGAAGTTGAACTACAGGA
AGAATTACAGTCGAAATTAATTTTACAATCTCATGAAGATGAAATCCCAG
AATTGGAATCGATTTGGCAGCTGACAGTTTATGAGAACGTAGCGGGAATC
AATCTGTTTAAATCGATATTATTGGAACAATATTTAGAAATGGCAAATAT
AACATCTCAACTCGATGGAAACGTTATCAGTAAAATTCCGGAATTTACTA
CCACTTCTTTCACTGTGGATTATAATGCAAGTTTGAGAAAATATCTCCAA
TTGTTGAGTGCACATGAAAATTATTTCAAAATATTAACGAATTCCATGAA
TATGTTTGGGATTTATCTCAATACCAATGAAGCGGGAATGGTGTGTAATA
TGATGGTCACATTACAAAAGGCATGCATCAATATTCTCACATTCGAGAGC
AAGTTTATCGATATAATAATGCCGGAATCGATAAAAATAATGAAACAGCT
AACTGCGGAAGATAACGAATTATTGAATAAATTGAAATCGATACTGAAAG
ACGGTGAAAACATAATGCTCCATTTCAATATTGCACTCACCTCAGCATCA
TATGATGTGAATAATTACGAGCATATCCATTTGAAAACCGTTGTGCCGAT
GAAAGAGAAAATCGCCGAATTAACCGATATTGGTAACTTTCCAATTCACG
ACAGCTCCAAACAGTTACGTATTCTCATTGCCAGTTTTTATACAACGATC
AATCAATCATATCTATTGGTCTGTGATTTTATTGATTGCTGCATGGGTTC
CTCCACTCCGAGTTCATGGAATTATATAGATTTAGTTGCAGCCAGCAGTA
TCAATATCTCTCCGATTTGGAATAAATCGATTAAGTTGCTGAAAGATGCG
CTTTACATGAGTGGAATCCGGTGCATGGTTAGCACACTTGATCACTGCAA
ATCAATTATCGATTCATTAACCATAAAGCAGGATCAATCTCAATTAGTAA
TTTTATTCAACAATATTCTACGCAATTTGGAAATTTATTTCAATTTCATC
ACTAAACACGTATTGGTCGGTGTTGGTAGTCAGTGCTTTGCAAAGATGTT
CTGCTTGCTACTTGAGCACGCTGGTTGGAATATCGATACATTGATTTCGG
AAAACGTGATCAACAACTGTGCTCTGAGTGCCGATTACATTTGCGGTAGC
GTTATTTCATTTAGAAAGCTCGAATATCCAAATGCCAACAATTTCTATAA
TCAACTTCAATTCAGATTTAATAACTATAAAAATATCGCTGGATTTTCGA
TAATTGAACCGAATACCATCTCACAGAGATTCCAAACTCGCAATGCTGCT
TTTCATAAATCATTGACAGGATTAGCGAGAAATCAATTACTGTCGTTGTG
TTGGACGAAAAAACATTTGATCAATGAAATTGATTTAAAGAATTGCGATC
TTTTACCATTAGAAGAACTGATCAATATTTTAAACGGTATTCCTAACCGA
ATCACGGCATTAAAAGAATTGCTTTCAAAATTAGACACAATAAGTTCGAA
ATTTCTGTTGGCCGATGAAAAACTATTATCGGAAATGAAAGAAGATTCGA
AAGATGCAATAATATGCCGATTGAATCAAGAAAGAACCCAATCGATAAAC
AGTGTTAAAAAACGAATTCTCCTGTTCAATGACGCTCTATTAAATATCGA
TCGGTTTGAATGTCTACGATCAGCCTCAGGACGTGGTAATCAATTCGACG
AAGAAGTCATACAATTTCTGTCGGAAAGTAAAGATCTCCTACAGAAACTA
TCAGAATGTGAAGGTTTAATAAAACCGATTGAAGAAGAAATAATAAAATT
AAAGGAGGAATATAAACTCAGTAGTGACACTGATTGGTATGTGGAATTGT
TGGAAATCCTACAGAAAGATATGGACAAAAATTCCAACGAAGTTCATCAA
AAAGAAAATCAAATGAAAGAAATTATAATATCTAATGAAAAAGAAGCCAG
AGGATTGAAAGAAAATCTTTCCGCTGATTATTATCCTTTGATAAATCATT
TGAAACCAAATCTCAGAATATTGTATACAGTGACGAAGAAATTGAAATCC
TATTTGTCAATTGATGAAAGTACATCGGGAACCAACAAACAAGACATCAA
ATCTAAAGTCGATCGGGTTTTGAAAATAATGAGCTTGTTTGAGAAATTCA
ACTTTACAATGGATGGATTAATGAAGTTCCTATTGAAAGGTGGCGATGGT
GAAATATCAATATATGAATATATAGGACAGCTGCACTATCAAATCAATAA
TCTCGCCATCATTAAGGATTCTATTGTTCCGGATTTGTTTATCACATTGC
TATCTCTGTCTCCATTGGAAACTGAAGACAAATCATCAATCTACATTTAC
GACTTCGATATTCCATCTAAGTTCGGTTTCAGCAACAATAACATGGCGGA
AATAAACGGCGCCGCCGACACGATGACTACTCGAATTTCTCCGTCTTTGT
CTGGAGAGGAAACTTCGTCCATTGTTGAAAACAATAAATCGAATCCAATT
AACAACATCATTAACTCTGAGTCGGATATTGTGGGGAAAAGATCAACCGA
CATTAACCTAGAAATCATAGAGAAAGATGAGAAAGATAAAAAGTATAATA
ATAACAACAGTGTTGCAGTTCAAAAAGCCATCGAAGTTTGGAAATTAACT
GAAACGAGATTGAATTCAGCTAATCAGAAACAACCATTGGCAAGTAATGA
ATATATCGAAATAAAAACCTCAAAGCCTGCAATCAATCAGTACATTGACA
AGTTGATAAAGTCTGCGAGAAGTGCAGAAAATTTGGCACGTATGTATGAA
GGCTGGACCGCTTGGGTTTGAAGGAGTCAATAGAAATAATAATAATAAAT
TTATGATTCAAGAATTTTGATAGCGATATAAAACCAACACCAGCTTTATT
TTTCAGACTCGAAGTATTCGGTATCGCAACATATAATAATACTAATAATC
TCTTTTATTTAAAATTGAATCAGGTAACCAGCTCCATAACACCAGAAATT
AAAATTAGATGCCACACAAGCTTCTCTAGTAATATGTGTAAGCTGTTTTG
GTATCGTCCTGCCAAATGTCTGATTTACTACTTCTAGCTCTCAAGATCCT
CAAATCAAGCCCATTTAATGATTTTAATTTGTTGTTTGAGAATATTGTGG
TATTGCTGATTTGTTTGCTGATTGGTTTGCTGTGGATGTGTCGTATGTGG
TTATAGTTTACTTTATGCTTCTATTGATGTGCTTTAAGACATTAACTTGG
CATTTGGAATATTGATTATTGTGTTACTCTGTTATATCTTTGAAATAAAT
AATTAGCTGTAAAAAAAA
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protein sequence of SMED30001428-orf-1

>SMED30001428-orf-1 ID=SMED30001428-orf-1|Name=SMED30001428-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3591bp
MDLFDSWFESIRNGNLKEIINIFKTNPDFINKFTTMNDGRNTYQTNAIIE
ASFQGNRDLVKWLIENNADVNSMSDGGWRPIHFAAQHGHVTTVNLLVLGG
AEVNVETEAKETPILFALQAYMRDTVKKLLHHGASLVGIDRNYLQMCIQK
DILDPAFLDEQNKAYLVDTSSYRKIDSNGFDIMSRQHDREIEEIKPVKLN
KAKIITEYDNELKRRRQDLLKKMRRTAEPVNTLGPLIRKLSQSENDSEKI
MVVKELIMICNQDGGVPQNKFSDQMINILELCICDSSSSDEFIVLSGKLM
MSLLHLNIRRGDAAIVDFWCRIFDKMTNLQIEQYTQQILKMLLKMIECST
EGVINNLKSNKDTFLKNWEYFFENLCFPKCLNLSLMILKSVFNHCPDVVI
DRFHNVIDIMIGWCIHPDTDLVTMEALCQRSVDLHECWISDTINLKKTLS
NLQKDFLTHCQMLSRIHRIDKDRSQIDDLKLKIKFFCFALSCVTAGVSKI
SDLNDVNFHENSSENLTEILSNVYIIGIIEKITEGLIMCSKQIDFDNLLL
QPNSVILHLLFILNKKEPIGTVYQSVFRYVLGTTLPLQSHILSEGSNNTN
YYNKQLIISYLDLISICLVNINLEPATVVQILSPVNWIHSCIFYGSFIDN
NLMQKYLRLVDIIAKSHCVTTFYQILLSDLELALNILMKISNCTNMVRLV
QSNAFKAKSYETPQAELVVKYNINLIIMLYNRLSDPSILVPSIPVLFTKY
LLFTESNIIVKYPNIASFLISTISKIKLSHDLIPDWIKFLCLIINTGNLS
FAIKSMGFEILKTVLATNKSILENSTELINLLVSSVCNLMSSESEKESIV
VSCLNIIVDNLNSYQTLINETNIDNLVAVNIIFSMHSSHLVRSKSIKIYF
DLITKTDSPISRKLFHKNLKSIQAISISGRSFKFPIDFSKSIFNWIIDST
DKYSFESRDIQRLHSIVAINQSKLEHLFCNRMIMVYEIIINACWDCVRQK
LKFDQNADSRITLMTIENMVKSILTNGNSLKAITDKRFRKLMTKFTSKTP
EDQSLSVNLMILLLDVLEKMFYNCYEGCCLGFPPVNKSIETFFVTNKNVC
IEWFIKMRLLIVALAQYSGQWSTVIWHGMQLLKFHLDKCNTHSSSAAKIL
VPEVEDCIVLTSMAYSKLGNWENLYGLSQLSVETYGSKFDWIEALADKTI
GRLEMALSKFEEYVRNHHDPERIKLSSEMRLLTRKTTSHSSFILCMEEIA
DCYKLLNNPDGLDQWKKQIQSWKSNSQIQEAQKLSINWARLVCLTKLSKW
DENMDDKCIPLRANELSWKYRSVIDNCEDSLFLSVVEKSSCKEVEIESFI
VKLSSIQSICDFPNTFTNPDIILINERLKLLKAANKGESFIVDCKNLSNF
STTLPLPVISFCNTIQKRYNIPQCFPNQKFLIKWHRNHLNFNKCHSLISH
SFTSFLGKEINQQSNLSNSQLPIIQMQIERELVKLLWEEDKKKDSLQLLT
SSLKDSLLFETSDSTLHSSKCQLNTKSLLTLFMWLCNEKSKFPKFCNDAK
ISSNLQFLIELAEVPWINGLPLVSPQHRSMEKTCQSSVTDVCSQLLILAS
KSRNQDNSDKSFMALAQWCLSRSRSLDEIGFNAETIDLATKLENQGFSSE
TICNIELLLKSNFCPSQMKTESDWFGDCYEDSGFLVELRQSILALDPEIT
SQMAEEVVKIWLEFVTHHFSLHIAAAEAYFSFLKDATPTKAKYSLCNKNK
TTANLRILSLIGKRSRSLRDSIINKIKTSPPGSWTNVIPQLFARLKHSDK
MIRNCMSELLQRLAISSNNCSKLIIYPTLVGSISENMNNSSPYHDIKKVL
VENNRQLVEEVGVFIKELRRITVLWDELWVSSLGQCYDELNKKAHQLQSE
IDKIDSQDDLKHKDVILKLKYNSIIQAAVFILERTKNATNMIPETPRESW
FHNMFAEEITSTIEEIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVK
LKRGRHQFLSLKLDDVSPGLAKINSSLIPLPGMNNKSLLSIDKHISILPT
KTKPKKFRFLSTNGKHYSYLYKGLEDLRLDERVMQILGIANTMFSKINEH
ESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLK
SKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDS
REKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSC
AVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFDKGVSLKVPEKV
PFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDP
IVDWSSGIESGHYGSFDGGKYAVNSSKSLIDKRSVEFIINLNNFQSVFIT
IEDDLKSCQEKLILDFRNLHEHLNRSWSTCKTIEEIKAAHNKKLQMIQYL
RGYETNNECKIVEQFNYVRKLEERSMHLELDIQKRQQQLKLVSMEHSAFF
NKILSAADFISLKLDIKNIKNFFEEHIENIEKSITVFCDQYSVTNPYGEI
IQELLFMLDNMEEIQNGLIVLEKYRNIIQEMPQSYYNSDRCSYMLQITEN
LLKTPSLSNIQRNFQNYSDWMIKDDQSSIEKFTNEKNNWNALLKVEVELQ
EELQSKLILQSHEDEIPELESIWQLTVYENVAGINLFKSILLEQYLEMAN
ITSQLDGNVISKIPEFTTTSFTVDYNASLRKYLQLLSAHENYFKILTNSM
NMFGIYLNTNEAGMVCNMMVTLQKACINILTFESKFIDIIMPESIKIMKQ
LTAEDNELLNKLKSILKDGENIMLHFNIALTSASYDVNNYEHIHLKTVVP
MKEKIAELTDIGNFPIHDSSKQLRILIASFYTTINQSYLLVCDFIDCCMG
SSTPSSWNYIDLVAASSINISPIWNKSIKLLKDALYMSGIRCMVSTLDHC
KSIIDSLTIKQDQSQLVILFNNILRNLEIYFNFITKHVLVGVGSQCFAKM
FCLLLEHAGWNIDTLISENVINNCALSADYICGSVISFRKLEYPNANNFY
NQLQFRFNNYKNIAGFSIIEPNTISQRFQTRNAAFHKSLTGLARNQLLSL
CWTKKHLINEIDLKNCDLLPLEELINILNGIPNRITALKELLSKLDTISS
KFLLADEKLLSEMKEDSKDAIICRLNQERTQSINSVKKRILLFNDALLNI
DRFECLRSASGRGNQFDEEVIQFLSESKDLLQKLSECEGLIKPIEEEIIK
LKEEYKLSSDTDWYVELLEILQKDMDKNSNEVHQKENQMKEIIISNEKEA
RGLKENLSADYYPLINHLKPNLRILYTVTKKLKSYLSIDESTSGTNKQDI
KSKVDRVLKIMSLFEKFNFTMDGLMKFLLKGGDGEISIYEYIGQLHYQIN
NLAIIKDSIVPDLFITLLSLSPLETEDKSSIYIYDFDIPSKFGFSNNNMA
EINGAADTMTTRISPSLSGEETSSIVENNKSNPINNIINSESDIVGKRST
DINLEIIEKDEKDKKYNNNNSVAVQKAIEVWKLTETRLNSANQKQPLASN
EYIEIKTSKPAINQYIDKLIKSARSAENLARMYEGWTAWV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000136whole organism
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR036770Ankyrin_rpt-contain_sf
IPR036940PI3/4_kinase_cat_sf
IPR039414SMG1_PIKKc
IPR003152FATC_dom
IPR000403PI3/4_kinase_cat_dom
IPR031559SMG1
IPR020683Ankyrin_rpt-contain_dom
IPR011009Kinase-like_dom_sf
IPR002110Ankyrin_rpt
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0016301kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0000166nucleotide binding
GO:0005524ATP binding
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0016310phosphorylation
GO:0006468protein phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 2468..2488
NoneNo IPR availableCOILSCoilCoilcoord: 1887..1907
NoneNo IPR availableCOILSCoilCoilcoord: 2798..2818
NoneNo IPR availableCOILSCoilCoilcoord: 1262..1282
NoneNo IPR availableCOILSCoilCoilcoord: 3268..3288
NoneNo IPR availableSMARTSM01345Rapamycin_bind_3coord: 1867..1985
e-value: 1.4E-5
score: 30.5
NoneNo IPR availableGENE3DG3DSA:3.30.1010.10coord: 1969..2126
e-value: 1.7E-11
score: 46.1
NoneNo IPR availablePFAMPF13637Ank_4coord: 47..97
e-value: 7.1E-9
score: 36.0
NoneNo IPR availablePANTHERPTHR11139ATAXIA TELANGIECTASIA MUTATED ATM -RELATEDcoord: 605..3590
NoneNo IPR availablePANTHERPTHR11139:SF71SERINE/THREONINE-PROTEIN KINASE SMG1coord: 605..3590
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainSMARTSM00146pi3k_hr1_6coord: 2068..2408
e-value: 1.4E-45
score: 167.4
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainPFAMPF00454PI3_PI4_kinasecoord: 2067..2356
e-value: 5.6E-51
score: 173.8
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainPROSITEPS50290PI3_4_KINASE_3coord: 2067..2349
score: 40.147
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 43..72
e-value: 2.3
score: 17.2
coord: 76..105
e-value: 0.029
score: 23.5
coord: 109..138
e-value: 860.0
score: 5.5
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 76..108
score: 11.888
IPR003152FATC domainSMARTSM01343FATC_2coord: 3558..3590
e-value: 4.1E-8
score: 42.9
IPR003152FATC domainPFAMPF02260FATCcoord: 3563..3589
e-value: 1.1E-8
score: 34.7
IPR003152FATC domainPROSITEPS51190FATCcoord: 3558..3590
score: 12.764
IPR031559Serine/threonine-protein kinase SMG1PFAMPF15785SMG1coord: 991..1281
e-value: 3.5E-34
score: 118.2
IPR036770Ankyrin repeat-containing domain superfamilyGENE3DG3DSA:1.25.40.20coord: 2..203
e-value: 4.4E-23
score: 83.9
IPR036770Ankyrin repeat-containing domain superfamilySUPERFAMILYSSF48403Ankyrin repeatcoord: 7..151
IPR036940Phosphatidylinositol 3-/4-kinase, catalytic domain superfamilyGENE3DG3DSA:1.10.1070.11coord: 2215..2363
e-value: 3.9E-31
score: 110.2
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 43..141
score: 24.427
IPR039414SMG1, PIKK catalytic domainCDDcd05170PIKKc_SMG1coord: 2038..2356
e-value: 4.7874E-169
score: 521.045
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 1973..2356