UPF0728 protein C10orf53 homolog

Overview
NameUPF0728 protein C10orf53 homolog
Smed IDSMED30001414
Length (bp)533
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of UPF0728 protein C10orf53 homolog (SMED30001414) t-SNE clustered cells

Violin plots show distribution of expression levels for UPF0728 protein C10orf53 homolog (SMED30001414) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of UPF0728 protein C10orf53 homolog (SMED30001414) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for UPF0728 protein C10orf53 homolog (SMED30001414) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001414

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30001414 SmedASXL_006013SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30001414 dd_Smed_v6_10501_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30001414 OX_Smed_1.0.01540ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30001414 Contig52941newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30001414 Contig52941uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30001414 dd_Smed_v4_10501_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Human
Match: C10orf53 (chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421])

HSP 1 Score: 72.7886 bits (177), Expect = 8.394e-17
Identity = 38/73 (52.05%), Postives = 53/73 (72.60%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            VEH T  L G++ +L  +GH VI +E ++  ++VEL VN+E +F CNIK+L+FGGDG++DPLC  A  AV NA
Sbjct:   21 VEHHTFRLQGLQAVLAIDGHEVI-LEKIEDWNVVELMVNEEVIFHCNIKDLEFGGDGKLDPLCEKARIAVLNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Human
Match: C10orf53 (chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421])

HSP 1 Score: 50.8322 bits (120), Expect = 2.213e-8
Identity = 26/54 (48.15%), Postives = 39/54 (72.22%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFG 351
            VEH T  L G++ +L  +GH VI +E ++  ++VEL VN+E +F CNIK+L+FG
Sbjct:   21 VEHHTFRLQGLQAVLAIDGHEVI-LEKIEDWNVVELMVNEEVIFHCNIKDLEFG 73
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Human
Match: C10orf53 (chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421])

HSP 1 Score: 50.447 bits (119), Expect = 9.635e-8
Identity = 26/54 (48.15%), Postives = 39/54 (72.22%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFG 351
            VEH T  L G++ +L  +GH VI +E ++  ++VEL VN+E +F CNIK+L+FG
Sbjct:   21 VEHHTFRLQGLQAVLAIDGHEVI-LEKIEDWNVVELMVNEEVIFHCNIKDLEFG 73
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Human
Match: C10orf53 (chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421])

HSP 1 Score: 50.447 bits (119), Expect = 9.635e-8
Identity = 26/54 (48.15%), Postives = 39/54 (72.22%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFG 351
            VEH T  L G++ +L  +GH VI +E ++  ++VEL VN+E +F CNIK+L+FG
Sbjct:   21 VEHHTFRLQGLQAVLAIDGHEVI-LEKIEDWNVVELMVNEEVIFHCNIKDLEFG 73
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Zebrafish
Match: C13H10orf53 (zgc:153142 [Source:NCBI gene;Acc:768197])

HSP 1 Score: 71.633 bits (174), Expect = 1.584e-16
Identity = 36/75 (48.00%), Postives = 50/75 (66.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GIV+H T  L G++ +L+ +GH  + +E  D  + VEL VN E+V+ CNI +L FGGDG +DPLC  A+ AV  A
Sbjct:   18 GIVDHRTFRLDGLQAVLKGDGHRYV-LEKTDDWNTVELIVNGERVYTCNITDLVFGGDGRLDPLCQEAIDAVREA 91
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Xenopus
Match: C10orf53 (chromosome 10 open reading frame 53 [Source:NCBI gene;Acc:100485377])

HSP 1 Score: 84.7297 bits (208), Expect = 2.253e-21
Identity = 42/75 (56.00%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            G+V+H  + L G++ +L  +GH VI  E LD R+ VEL VN E VF CNIK LDFGGDG++DPLC  A +AV NA
Sbjct:   19 GLVDHRVSRLQGLRAVLVSDGHQVILEEILD-RNTVELIVNGELVFRCNIKELDFGGDGQLDPLCEEARKAVKNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Mouse
Match: 1700024G13Rik (RIKEN cDNA 1700024G13 gene [Source:MGI Symbol;Acc:MGI:1914335])

HSP 1 Score: 77.0258 bits (188), Expect = 1.440e-18
Identity = 38/73 (52.05%), Postives = 54/73 (73.97%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            VEH T  L G++ +L K+GH +I +E ++  +LVEL VN+E VF+C+I+ L+FGGDG++DPLC  A  AV NA
Sbjct:   21 VEHRTYRLQGLQAVLAKDGHQII-LEQIEDWNLVELVVNEETVFQCDIQELEFGGDGKLDPLCEEARIAVLNA 92
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BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Match: sp|P0C921|CJ053_XENTR (UPF0728 protein C10orf53 homolog OS=Xenopus tropicalis OX=8364 PE=3 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 5.516e-20
Identity = 41/75 (54.67%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            G+V+H  + L G++ +L  +GH VI  E LD R+ VEL VN E VF CNIK LDFGGDG++DPLC  A +AV +A
Sbjct:   19 GLVDHRVSRLQGLRAVLVSDGHQVILEEILD-RNTVELIVNGELVFRCNIKELDFGGDGQLDPLCEEARKAVKDA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Match: sp|A7SG48|U728_NEMVE (UPF0728 protein v1g117062 OS=Nematostella vectensis OX=45351 GN=v1g117062 PE=3 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 7.872e-18
Identity = 39/75 (52.00%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GI+++ TA L G++ LL  +GH+V F +T D RD VEL V+ E VF C I++L +GGDG++DP CH AL AV  A
Sbjct:   17 GILQYKTARLEGLQELLLSDGHSVEFEKTED-RDDVELVVHGEIVFRCKIQDLQYGGDGKLDPTCHRALEAVQKA 90
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Match: sp|Q3KNL4|CJ053_MOUSE (UPF0728 protein C10orf53 homolog OS=Mus musculus OX=10090 PE=3 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 1.007e-17
Identity = 38/73 (52.05%), Postives = 54/73 (73.97%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            VEH T  L G++ +L K+GH +I +E ++  +LVEL VN+E VF+C+I+ L+FGGDG++DPLC  A  AV NA
Sbjct:   21 VEHRTYRLQGLQAVLAKDGHQII-LEQIEDWNLVELVVNEETVFQCDIQELEFGGDGKLDPLCEEARIAVLNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Match: sp|Q8N6V4|CJ053_HUMAN (UPF0728 protein C10orf53 OS=Homo sapiens OX=9606 GN=C10orf53 PE=3 SV=3)

HSP 1 Score: 72.7886 bits (177), Expect = 4.031e-16
Identity = 38/73 (52.05%), Postives = 53/73 (72.60%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            VEH T  L G++ +L  +GH VI +E ++  ++VEL VN+E +F CNIK+L+FGGDG++DPLC  A  AV NA
Sbjct:   21 VEHHTFRLQGLQAVLAIDGHEVI-LEKIEDWNVVELMVNEEVIFHCNIKDLEFGGDGKLDPLCEKARIAVLNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Match: sp|P0C920|CJ053_BOVIN (UPF0728 protein C10orf53 homolog OS=Bos taurus OX=9913 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 8.260e-16
Identity = 38/73 (52.05%), Postives = 52/73 (71.23%), Query Frame = 1 
Query:  190 VEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            VEH T  L G+  +L ++GH V+ +E ++  ++VEL VN E VF CNIK+L+FGGDG++DPLC  A  AV NA
Sbjct:   21 VEHRTYRLEGLLAVLAEDGHQVL-LEKIEDWNVVELMVNGEVVFRCNIKDLEFGGDGKLDPLCREARIAVLNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Match: A0A5G3H909 (Chromosome 10 open reading frame 53 OS=Xenopus tropicalis OX=8364 GN=c10orf53 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 3.537e-18
Identity = 42/75 (56.00%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            G+V+H  + L G++ +L  +GH VI  E LD R+ VEL VN E VF CNIK LDFGGDG++DPLC  A +AV NA
Sbjct:   19 GLVDHRVSRLQGLRAVLVSDGHQVILEEILD-RNTVELIVNGELVFRCNIKELDFGGDGQLDPLCEEARKAVKNA 92
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Match: A0A2T7PZ34 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_01275 PE=4 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.012e-17
Identity = 38/75 (50.67%), Postives = 58/75 (77.33%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GIVEH T+ L G++T+L++ GHT   +  ++ R++VEL+VN E VF+C+I++L++GGDGE+DPLC  A +AV  A
Sbjct:   18 GIVEHRTSRLEGLQTILQRGGHTTT-LHCINDRNVVELWVNGELVFQCDIRDLEYGGDGELDPLCADAAKAVTRA 91
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Match: A0A402EIJ9 (Uncharacterized protein OS=Paroedura picta OX=143630 GN=parPi_0003310 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.103e-17
Identity = 41/75 (54.67%), Postives = 55/75 (73.33%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            G+VEH T  L G++ +L+++GH V+  ET D  D V+L VN E VF+CNI +LDFGGDG++DPLC  A +AV NA
Sbjct:   18 GVVEHRTFRLQGLQAVLKEDGHEVVLEETQDWND-VQLIVNGETVFQCNINDLDFGGDGKLDPLCEEARKAVLNA 91
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Match: A0A2B4SCD4 (UPF0728 protein C10orf53-like OS=Stylophora pistillata OX=50429 GN=AWC38_SpisGene9256 PE=4 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 1.566e-17
Identity = 41/75 (54.67%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GIVEH TA L G++ LL   GHTV F++T D RD VEL V+ E ++ C I+ L +GGDG++DP+C  AL AVN A
Sbjct:   17 GIVEHRTARLEGLQALLRSEGHTVEFVKTPD-RDDVELVVHGEIIYRCKIQALQYGGDGKLDPVCKEALAAVNKA 90
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Match: A0A4W5R9X7 (Zgc:153142 OS=Hucho hucho OX=62062 PE=4 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 5.207e-16
Identity = 39/75 (52.00%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GIV+H T  LIG++  L++NGH  + +E +   + VEL VN E V+ CNIK L+FGGDG++DPLC  A+ AV NA
Sbjct:   18 GIVDHRTFRLIGLQAALKENGHQSV-LEKMSDWNKVELVVNGECVYTCNIKQLEFGGDGKLDPLCKEAVTAVQNA 91
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Cavefish
Match: zgc:153142 (chromosome 25 C10orf53 homolog [Source:NCBI gene;Acc:103044032])

HSP 1 Score: 67.0106 bits (162), Expect = 8.783e-15
Identity = 32/75 (42.67%), Postives = 52/75 (69.33%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            G+VE+ T  L G++  L+  G++ +  +T +  + VEL VN E V++C+IK+L+FGGDG++DP C  A +AV +A
Sbjct:   18 GVVEYRTFRLDGLRAALKACGYSPVLEKTPEW-NQVELVVNGEIVYKCSIKDLEFGGDGKLDPRCQEATQAVKSA 91
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Nematostella
Match: EDO37318 (UPF0728 protein v1g117062 [Source:UniProtKB/Swiss-Prot;Acc:A7SG48])

HSP 1 Score: 77.411 bits (189), Expect = 3.227e-19
Identity = 39/75 (52.00%), Postives = 53/75 (70.67%), Query Frame = 1 
Query:  184 GIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            GI+++ TA L G++ LL  +GH+V F +T D RD VEL V+ E VF C I++L +GGDG++DP CH AL AV  A
Sbjct:   17 GILQYKTARLEGLQELLLSDGHSVEFEKTED-RDDVELVVHGEIVFRCKIQDLQYGGDGKLDPTCHRALEAVQKA 90
[Close]
BLAST of UPF0728 protein C10orf53 homolog vs. Planmine SMEST
Match: SMESG000073355.1 (SMESG000073355.1)

HSP 1 Score: 156.377 bits (394), Expect = 6.728e-50
Identity = 92/92 (100.00%), Postives = 92/92 (100.00%), Query Frame = 1 
Query:  133 MPIPXXXXXXXXXXXXXGIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 408
            MPIPAEVYLYYAAYEAYGIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA
Sbjct:    1 MPIPAEVYLYYAAYEAYGIVEHSTAPLIGMKTLLEKNGHTVIFIETLDIRDLVELFVNDEKVFECNIKNLDFGGDGEMDPLCHLALRAVNNA 92
The following BLAST results are available for this feature:
BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
C10orf538.394e-1752.05chromosome 10 open reading frame 53 [Source:HGNC S... [more]
C10orf532.213e-848.15chromosome 10 open reading frame 53 [Source:HGNC S... [more]
C10orf539.635e-848.15chromosome 10 open reading frame 53 [Source:HGNC S... [more]
C10orf539.635e-848.15chromosome 10 open reading frame 53 [Source:HGNC S... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C13H10orf531.584e-1648.00zgc:153142 [Source:NCBI gene;Acc:768197][more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C10orf532.253e-2156.00chromosome 10 open reading frame 53 [Source:NCBI g... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
1700024G13Rik1.440e-1852.05RIKEN cDNA 1700024G13 gene [Source:MGI Symbol;Acc:... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P0C921|CJ053_XENTR5.516e-2054.67UPF0728 protein C10orf53 homolog OS=Xenopus tropic... [more]
sp|A7SG48|U728_NEMVE7.872e-1852.00UPF0728 protein v1g117062 OS=Nematostella vectensi... [more]
sp|Q3KNL4|CJ053_MOUSE1.007e-1752.05UPF0728 protein C10orf53 homolog OS=Mus musculus O... [more]
sp|Q8N6V4|CJ053_HUMAN4.031e-1652.05UPF0728 protein C10orf53 OS=Homo sapiens OX=9606 G... [more]
sp|P0C920|CJ053_BOVIN8.260e-1652.05UPF0728 protein C10orf53 homolog OS=Bos taurus OX=... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A5G3H9093.537e-1856.00Chromosome 10 open reading frame 53 OS=Xenopus tro... [more]
A0A2T7PZ341.012e-1750.67Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A402EIJ91.103e-1754.67Uncharacterized protein OS=Paroedura picta OX=1436... [more]
A0A2B4SCD41.566e-1754.67UPF0728 protein C10orf53-like OS=Stylophora pistil... [more]
A0A4W5R9X75.207e-1652.00Zgc:153142 OS=Hucho hucho OX=62062 PE=4 SV=1[more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
zgc:1531428.783e-1542.67chromosome 25 C10orf53 homolog [Source:NCBI gene;A... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO373183.227e-1952.00UPF0728 protein v1g117062 [Source:UniProtKB/Swiss... [more]
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BLAST of UPF0728 protein C10orf53 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of UPF0728 protein C10orf53 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000073355.16.728e-50100.00SMESG000073355.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001414 ID=SMED30001414|Name=UPF0728 protein C10orf53 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=533bp
ACACAAAAATGAAATTTTGAAATTTTATTTTAAATCACTTTAATTTCTAA
GAAAAATCTCAATTTAACTGATTAATTTAATAATTTTTTAAATCTTAATC
TTTACTTGTTAAATTATATATAAGTTGATAATATGCCGATTCCGGCTGAA
GTCTACCTTTATTATGCTGCATACGAAGCATATGGAATTGTGGAACACAG
TACAGCTCCATTAATTGGAATGAAAACTTTGTTAGAAAAAAATGGCCACA
CTGTCATATTTATCGAAACTCTTGATATTAGAGATTTAGTTGAATTGTTT
GTAAATGATGAAAAGGTTTTTGAATGTAACATTAAAAATCTAGATTTCGG
TGGAGATGGTGAAATGGATCCTTTATGTCATTTAGCACTCCGGGCTGTTA
ATAATGCTTTTTAATTATTTTTCTTTATAAGTTTCACTCAGTAATTCTAC
AAATTATAAATAAATTATATGAAATTGTATAATAAAATACATCAGAAATT
TTTGAAAAAAAAAAAAAAAAAAAAAAAATGCGA
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR027885UPF0728
Vocabulary: molecular function
TermDefinition
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR027885Uncharacterised protein family UPF0728PFAMPF15092UPF0728coord: 1..89
e-value: 3.9E-26
score: 90.7
IPR027885Uncharacterised protein family UPF0728PANTHERPTHR28448FAMILY NOT NAMEDcoord: 1..93