P/Homo B domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001371 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 16Note: Hover over icons to view figure legend
Homology
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Match: PCSK1 (proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743]) HSP 1 Score: 287.345 bits (734), Expect = 8.480e-85 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKS-FTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S F KR + + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W +V + + CV K + ++ + + T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 22 LFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECV-VKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDM-----SGRIQNEGRIVNWKLILHGTSS 549
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Match: PCSK1 (proprotein convertase subtilisin/kexin type 1 [Source:HGNC Symbol;Acc:HGNC:8743]) HSP 1 Score: 287.73 bits (735), Expect = 1.757e-84 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKS-FTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S F KR + + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W +V + + CV K + ++ + + T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 69 LFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECV-VKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDM-----SGRIQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Match: PCSK5 (proprotein convertase subtilisin/kexin type 5 [Source:HGNC Symbol;Acc:HGNC:8747]) HSP 1 Score: 286.189 bits (731), Expect = 1.857e-84 Identity = 190/501 (37.92%), Postives = 284/501 (56.69%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGL-DMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNE-IQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
FNDP+ +W + D +P DMN+ +K +G+ +VV+++DDGI+ H ++++N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+AFNA +GG+RML + VTD++EA +++ N Q++ IYS SWGP D G ++A E G R GR+G GS++++A+GNGG + DHC DG+ NS YTI++++T G+KP Y EEC++ T YS+ +D+ ++ + +C + GTSA+ P+ +G IALALEAN FL WRD+QH+ + R + W+ N AG VSH YGFGL+D A V A+ W TV + VCV ++ +I IR R ++ +GC++ N + LEHV + I HP RGDL I LTSP+ T+S LL R+ D + + F++ WGE G W ++ D + K+ G L E L +GT+
Sbjct: 126 FNDPKWPSMWYMHCS---DNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPM--------PRY--DASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGD-VTDMVEAKSVSFNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATT----YSSGESYDKK-----IITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPRQHVCV--ESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTP--GKLKEWSLVLYGTS 599
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Match: PCSK6 (proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]) HSP 1 Score: 281.567 bits (719), Expect = 1.977e-83 Identity = 192/498 (38.55%), Postives = 280/498 (56.22%), Query Frame = 3
Query: 648 KTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDL 2123
K ++ + RR+ Q + FNDP +W Y + G + +MN+ +K +G+ VVV+++DDGI+ H ++ N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS SWGP D G ++A E G ++GR+G GSI+++A+GNGG D+C DG+ NS YTI+V++ +G KP Y EECA+ T YS+ ++R +V + +C + GTS + P+++G IALALEAN+ L WRD+QHL + R + + W++N AG VSH YGFGL+D A V A+ W V +CV K + + + + R T T+ CA ++D + LEHV + T I HP RGDL I L SP+ TKS LL +R+ D +N T + F++ WGE G+W +I DL
Sbjct: 136 KWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMW-YLHCGDKNSRCRS-EMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDP--------SPRY--DASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLV--QVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDL 609
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Match: PCSK6 (proprotein convertase subtilisin/kexin type 6 [Source:HGNC Symbol;Acc:HGNC:8569]) HSP 1 Score: 281.952 bits (720), Expect = 2.432e-83 Identity = 192/498 (38.55%), Postives = 280/498 (56.22%), Query Frame = 3
Query: 648 KTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDL 2123
K ++ + RR+ Q + FNDP +W Y + G + +MN+ +K +G+ VVV+++DDGI+ H ++ N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS SWGP D G ++A E G ++GR+G GSI+++A+GNGG D+C DG+ NS YTI+V++ +G KP Y EECA+ T YS+ ++R +V + +C + GTS + P+++G IALALEAN+ L WRD+QHL + R + + W++N AG VSH YGFGL+D A V A+ W V +CV K + + + + R T T+ CA ++D + LEHV + T I HP RGDL I L SP+ TKS LL +R+ D +N T + F++ WGE G+W +I DL
Sbjct: 136 KWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMW-YLHCGDKNSRCRS-EMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDP--------SPRY--DASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLV--QVLRTTALTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQDL 609
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Match: kpc-1 (Furin-like protease kpc-1 [Source:UniProtKB/Swiss-Prot;Acc:O17798]) HSP 1 Score: 265.388 bits (677), Expect = 3.599e-77 Identity = 184/514 (35.80%), Postives = 283/514 (55.06%), Query Frame = 3
Query: 606 KKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQ---YYNYGQF-DEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC--ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLG 2126
K+ + +R+ + E+D + ++ R+ K DP D LW Y N G+ + +D N+ + +G+GVVV+++DDG++ H +I N+D AS D+ND N DP PRY + +N HGT CA +A NN +C +G+A+NAN+GGIRML + VTD +EA ++ HN YIDIYS SWGP D G + A E G GRKG+GSI+++A+GNGG + D C DG+ NS YT+++++ +G P Y+E C++ T G ++ + ++ ++ C GTSA+ PL +G +ALALEAN L WRD+QH+ + + N W N G VSH +G+GL+D A V+ A++W V + C + ++ I G + ++ + GC +N++ +EHV+ ++ P RGDL I LTSP+ TKS LL +R RDT+ + T ++F++ NWGE G W +I + G
Sbjct: 138 KRGYRRIRRHTDDNDIFEEDDDGTQISKSRNR-----KHPDPN-DPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTHPDISPNYDERASYDVNDRDN---DPM-PRY--EFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNANIGGIRMLDGD-VTDAVEAASVGHNADYIDIYSASWGPDDDGRTVDGPAKLTRSAFEKGITMGRKGKGSIFVWASGNGGKDADSCNCDGYTNSIYTLSISSATENGNIPWYSEACSSTLATTYSSG---------ATGEKMILTTDLHHACTNMHTGTSASAPLAAGIVALALEANPNLTWRDLQHIVIRTAKPINLRAGDWTTNGVGRNVSHSFGYGLMDAGAMVKLAKIWKKVDEQHRCR--QFYPSRYKNIPNGNRLQLQLYSDGCYGGADENKVSYVEHVQAIVTLKAPKRGDLQIYLTSPSGTKSTLLTKRARDTSRSGFTDWAFMTTHNWGEQAAGLWILEIDNDG 627
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Match: kpc-1 (Furin-like protease kpc-1 [Source:UniProtKB/Swiss-Prot;Acc:O17798]) HSP 1 Score: 265.388 bits (677), Expect = 3.599e-77 Identity = 184/514 (35.80%), Postives = 283/514 (55.06%), Query Frame = 3
Query: 606 KKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQ---YYNYGQF-DEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC--ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLG 2126
K+ + +R+ + E+D + ++ R+ K DP D LW Y N G+ + +D N+ + +G+GVVV+++DDG++ H +I N+D AS D+ND N DP PRY + +N HGT CA +A NN +C +G+A+NAN+GGIRML + VTD +EA ++ HN YIDIYS SWGP D G + A E G GRKG+GSI+++A+GNGG + D C DG+ NS YT+++++ +G P Y+E C++ T G ++ + ++ ++ C GTSA+ PL +G +ALALEAN L WRD+QH+ + + N W N G VSH +G+GL+D A V+ A++W V + C + ++ I G + ++ + GC +N++ +EHV+ ++ P RGDL I LTSP+ TKS LL +R RDT+ + T ++F++ NWGE G W +I + G
Sbjct: 138 KRGYRRIRRHTDDNDIFEEDDDGTQISKSRNR-----KHPDPN-DPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTHPDISPNYDERASYDVNDRDN---DPM-PRY--EFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNANIGGIRMLDGD-VTDAVEAASVGHNADYIDIYSASWGPDDDGRTVDGPAKLTRSAFEKGITMGRKGKGSIFVWASGNGGKDADSCNCDGYTNSIYTLSISSATENGNIPWYSEACSSTLATTYSSG---------ATGEKMILTTDLHHACTNMHTGTSASAPLAAGIVALALEANPNLTWRDLQHIVIRTAKPINLRAGDWTTNGVGRNVSHSFGYGLMDAGAMVKLAKIWKKVDEQHRCR--QFYPSRYKNIPNGNRLQLQLYSDGCYGGADENKVSYVEHVQAIVTLKAPKRGDLQIYLTSPSGTKSTLLTKRARDTSRSGFTDWAFMTTHNWGEQAAGLWILEIDNDG 627
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Match: bli-4 (Endoprotease bli-4 [Source:UniProtKB/Swiss-Prot;Acc:P51559]) HSP 1 Score: 253.447 bits (646), Expect = 5.055e-73 Identity = 181/483 (37.47%), Postives = 260/483 (53.83%), Query Frame = 3
Query: 675 RRLVNQRHES---LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYE--AVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGK-KTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKW 2102
RR Q+ +S + S F DP W Y + G G DMN+ + +GR V VS++DDGI H ++ N+DP AS D+ND + DP + N HGT CA +A + N CG+GVAF A +GG+RML V+D +EA +L+ N +IDIYS SWGP+D G ++A G + GR G+G+I+++A+GNGG D C DG+ S YT+++++ +P Y EEC + T YS+ DF + P +V + G C ++ GTSA+ PL +G IALALEAN L WRD+QHL + P E W N G +VS+++G+GL+D A V A+ W TV + +C +N + G+ + T GC + + LEHV++H + + RGDL ++L SP+ T+SVLL R +D N N + FLS WGE+PRG W
Sbjct: 142 RRAQRQQPQSPREIPSLPFPDPLYKDQW-YLHGGAVG----GYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDD---DP-----TPQNNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLD-GAVSDSVEAASLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATT----YSS-ADFRQ----PAIVTVDVPGGCTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANW-KPLENNPGWSRNGVGRMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGC-ESGTPVLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSVQQWGEDPRGTW 599
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Match: bli-4 (Endoprotease bli-4 [Source:UniProtKB/Swiss-Prot;Acc:P51559]) HSP 1 Score: 253.447 bits (646), Expect = 5.055e-73 Identity = 181/483 (37.47%), Postives = 260/483 (53.83%), Query Frame = 3
Query: 675 RRLVNQRHES---LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYE--AVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGK-KTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKW 2102
RR Q+ +S + S F DP W Y + G G DMN+ + +GR V VS++DDGI H ++ N+DP AS D+ND + DP + N HGT CA +A + N CG+GVAF A +GG+RML V+D +EA +L+ N +IDIYS SWGP+D G ++A G + GR G+G+I+++A+GNGG D C DG+ S YT+++++ +P Y EEC + T YS+ DF + P +V + G C ++ GTSA+ PL +G IALALEAN L WRD+QHL + P E W N G +VS+++G+GL+D A V A+ W TV + +C +N + G+ + T GC + + LEHV++H + + RGDL ++L SP+ T+SVLL R +D N N + FLS WGE+PRG W
Sbjct: 142 RRAQRQQPQSPREIPSLPFPDPLYKDQW-YLHGGAVG----GYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDD---DP-----TPQNNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLD-GAVSDSVEAASLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATT----YSS-ADFRQ----PAIVTVDVPGGCTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANW-KPLENNPGWSRNGVGRMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGC-ESGTPVLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSVQQWGEDPRGTW 599
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Match: bli-4 (Endoprotease bli-4 [Source:UniProtKB/Swiss-Prot;Acc:P51559]) HSP 1 Score: 252.292 bits (643), Expect = 1.001e-72 Identity = 180/482 (37.34%), Postives = 259/482 (53.73%), Query Frame = 3
Query: 675 RRLVNQRHES---LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHL-FTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGK-KTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKW 2102
RR Q+ +S + S F DP W Y + G G DMN+ + +GR V VS++DDGI H ++ N+DP AS D+ND + DP + N HGT CA +A + N CG+GVAF A +GG+RML V+D +EA +L+ N +IDIYS SWGP+D G ++A G + GR G+G+I+++A+GNGG D C DG+ S YT+++++ +P Y EEC + T YS+ DF + P +V + G C ++ GTSA+ PL +G IALALEAN L WRD+QHL + P W N G +VS+++G+GL+D A V A+ W TV + +C +N + G+ + T GC + + LEHV++H + + RGDL ++L SP+ T+SVLL R +D N N + FLS WGE+PRG W
Sbjct: 142 RRAQRQQPQSPREIPSLPFPDPLYKDQW-YLHGGAVG----GYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDD---DP-----TPQNNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLD-GAVSDSVEAASLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATT----YSS-ADFRQ----PAIVTVDVPGGCTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANWKPLENNPGWSRNGVGRMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGC-ESGTPVLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSVQQWGEDPRGTW 599
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Match: Fur2 (gene:FBgn0004598 transcript:FBtr0074262) HSP 1 Score: 258.84 bits (660), Expect = 1.378e-71 Identity = 189/500 (37.80%), Postives = 270/500 (54.00%), Query Frame = 3
Query: 714 FKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAA-ISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA--VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F F DP + W Y N G D GLDMN+ ++ +G+GVVVS++DDGI T H ++ +N+DP AS D+N SDP + N HGT CA +A + N CG+GVA+NA++GG+RML V D++EA AL+ N +IDIYS SWGP+D G ++A G GR+G+GSI+++A+GNGG D C DG+ NS +T+++++ G KP Y EEC++ ++ T + G D +D L I C GTSA+ PL +G ALALEAN L WRD+Q+L + R P P E W LN SH++G+GL+D A V A+ W +V +C + ++ + G GCA T NE++ LEHV+ + RG+L I LTSP T S LL +R RD +N + FLS WGE G+W +++ G ++ + G L + L F+GT+
Sbjct: 373 FIFPDPLFKEQW-YLNGGAKD----GLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGND---SDP-----TPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLD-GKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHI---CTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR-PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVIN----GGRRRVNQPGILSKWQLIFYGTS 850
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Match: Fur2 (gene:FBgn0004598 transcript:FBtr0074267) HSP 1 Score: 258.84 bits (660), Expect = 1.378e-71 Identity = 189/500 (37.80%), Postives = 270/500 (54.00%), Query Frame = 3
Query: 714 FKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAA-ISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA--VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F F DP + W Y N G D GLDMN+ ++ +G+GVVVS++DDGI T H ++ +N+DP AS D+N SDP + N HGT CA +A + N CG+GVA+NA++GG+RML V D++EA AL+ N +IDIYS SWGP+D G ++A G GR+G+GSI+++A+GNGG D C DG+ NS +T+++++ G KP Y EEC++ ++ T + G D +D L I C GTSA+ PL +G ALALEAN L WRD+Q+L + R P P E W LN SH++G+GL+D A V A+ W +V +C + ++ + G GCA T NE++ LEHV+ + RG+L I LTSP T S LL +R RD +N + FLS WGE G+W +++ G ++ + G L + L F+GT+
Sbjct: 373 FIFPDPLFKEQW-YLNGGAKD----GLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGND---SDP-----TPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLD-GKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHI---CTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR-PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVIN----GGRRRVNQPGILSKWQLIFYGTS 850
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Match: Fur2 (gene:FBgn0004598 transcript:FBtr0074266) HSP 1 Score: 258.84 bits (660), Expect = 1.378e-71 Identity = 189/500 (37.80%), Postives = 270/500 (54.00%), Query Frame = 3
Query: 714 FKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAA-ISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA--VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F F DP + W Y N G D GLDMN+ ++ +G+GVVVS++DDGI T H ++ +N+DP AS D+N SDP + N HGT CA +A + N CG+GVA+NA++GG+RML V D++EA AL+ N +IDIYS SWGP+D G ++A G GR+G+GSI+++A+GNGG D C DG+ NS +T+++++ G KP Y EEC++ ++ T + G D +D L I C GTSA+ PL +G ALALEAN L WRD+Q+L + R P P E W LN SH++G+GL+D A V A+ W +V +C + ++ + G GCA T NE++ LEHV+ + RG+L I LTSP T S LL +R RD +N + FLS WGE G+W +++ G ++ + G L + L F+GT+
Sbjct: 373 FIFPDPLFKEQW-YLNGGAKD----GLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGND---SDP-----TPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLD-GKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHI---CTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR-PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVIN----GGRRRVNQPGILSKWQLIFYGTS 850
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Match: Fur2 (gene:FBgn0004598 transcript:FBtr0074264) HSP 1 Score: 258.84 bits (660), Expect = 1.378e-71 Identity = 189/500 (37.80%), Postives = 270/500 (54.00%), Query Frame = 3
Query: 714 FKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAA-ISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA--VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F F DP + W Y N G D GLDMN+ ++ +G+GVVVS++DDGI T H ++ +N+DP AS D+N SDP + N HGT CA +A + N CG+GVA+NA++GG+RML V D++EA AL+ N +IDIYS SWGP+D G ++A G GR+G+GSI+++A+GNGG D C DG+ NS +T+++++ G KP Y EEC++ ++ T + G D +D L I C GTSA+ PL +G ALALEAN L WRD+Q+L + R P P E W LN SH++G+GL+D A V A+ W +V +C + ++ + G GCA T NE++ LEHV+ + RG+L I LTSP T S LL +R RD +N + FLS WGE G+W +++ G ++ + G L + L F+GT+
Sbjct: 373 FIFPDPLFKEQW-YLNGGAKD----GLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGND---SDP-----TPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLD-GKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHI---CTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR-PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVIN----GGRRRVNQPGILSKWQLIFYGTS 850
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Match: Fur2 (gene:FBgn0004598 transcript:FBtr0301301) HSP 1 Score: 258.455 bits (659), Expect = 1.576e-71 Identity = 189/500 (37.80%), Postives = 270/500 (54.00%), Query Frame = 3
Query: 714 FKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAA-ISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA--VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F F DP + W Y N G D GLDMN+ ++ +G+GVVVS++DDGI T H ++ +N+DP AS D+N SDP + N HGT CA +A + N CG+GVA+NA++GG+RML V D++EA AL+ N +IDIYS SWGP+D G ++A G GR+G+GSI+++A+GNGG D C DG+ NS +T+++++ G KP Y EEC++ ++ T + G D +D L I C GTSA+ PL +G ALALEAN L WRD+Q+L + R P P E W LN SH++G+GL+D A V A+ W +V +C + ++ + G GCA T NE++ LEHV+ + RG+L I LTSP T S LL +R RD +N + FLS WGE G+W +++ G ++ + G L + L F+GT+
Sbjct: 349 FIFPDPLFKEQW-YLNGGAKD----GLDMNVGPAWQKGYTGKGVVVSILDDGIQTNHPDLAQNYDPEASFDINGND---SDP-----TPQDNGDNKHGTRCAGEVAAVAFNNFCGVGVAYNASIGGVRMLD-GKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHI---CTVEHTGTSASAPLAAGICALALEANPELTWRDMQYLVVYTSR-PAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVIN----GGRRRVNQPGILSKWQLIFYGTS 826
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Match: pcsk1 (proprotein convertase subtilisin/kexin type 1 [Source:ZFIN;Acc:ZDB-GENE-071009-1]) HSP 1 Score: 293.893 bits (751), Expect = 6.805e-87 Identity = 194/520 (37.31%), Postives = 297/520 (57.12%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRG-PRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDT-NNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIH 2264
F+DP ++ W Y + P LD+++ V+K I+G+GVV++V+DDG++ H +I N+DPAAS D ND +DP PRY + +N HGT CA IA +++N CG+GVA+N+ +GGIRML +VTD +EA ++ +N ++DIYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD + +A ++ +C E GTSA+ PL +G ALALE N L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + ++W V + + C+ + ++ + ++ + + T CA N + +LEHV++ IE+ RGDL I+LTSP+ T +VLL +R RDT +N ++F+S WGENP G W I D +S + G ++ L HGT+ + H K + T + +
Sbjct: 124 FDDPMWNQQW-YLQDTRTSSSLPKLDLHVIPVWKKGITGKGVVITVLDDGLEWNHTDIYPNYDPAASYDFND-----NDPDPFPRYDS--TNENKHGTRCAGEIAMQADNNKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGYNPDHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGIQKGRGGKGSIFVWASGNGGRQGDNCDCDGYTDSLYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------ITSADLHNECTETHTGTSASAPLAAGIFALALEQNPDLTWRDLQHLVVWTSEFDPLANNPGWKRNGAGLMVNSRFGFGLLNAKALVDLADPKVWKHVPEKKQCI-VRDETFQPRPLKAAGEISIEIPTKACAGQANSVMSLEHVQVEVSIEYTRRGDLHITLTSPSGTTTVLLAERERDTSSNGFRNWAFMSVHTWGENPTGTWILKITD-----TSGRMENEGQIISWKLILHGTS--EKPEHMKKARVYTPYNAVQ 617
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Match: pcsk1 (proprotein convertase subtilisin/kexin type 1 [Source:ZFIN;Acc:ZDB-GENE-071009-1]) HSP 1 Score: 293.508 bits (750), Expect = 8.782e-87 Identity = 194/520 (37.31%), Postives = 297/520 (57.12%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRG-PRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDT-NNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIH 2264
F+DP ++ W Y + P LD+++ V+K I+G+GVV++V+DDG++ H +I N+DPAAS D ND +DP PRY + +N HGT CA IA +++N CG+GVA+N+ +GGIRML +VTD +EA ++ +N ++DIYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD + +A ++ +C E GTSA+ PL +G ALALE N L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + ++W V + + C+ + ++ + ++ + + T CA N + +LEHV++ IE+ RGDL I+LTSP+ T +VLL +R RDT +N ++F+S WGENP G W I D +S + G ++ L HGT+ + H K + T + +
Sbjct: 124 FDDPMWNQQW-YLQDTRTSSSLPKLDLHVIPVWKKGITGKGVVITVLDDGLEWNHTDIYPNYDPAASYDFND-----NDPDPFPRYDS--TNENKHGTRCAGEIAMQADNNKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGYNPDHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGIQKGRGGKGSIFVWASGNGGRQGDNCDCDGYTDSLYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------ITSADLHNECTETHTGTSASAPLAAGIFALALEQNPDLTWRDLQHLVVWTSEFDPLANNPGWKRNGAGLMVNSRFGFGLLNAKALVDLADPKVWKHVPEKKQCI-VRDETFQPRPLKAAGEISIEIPTKACAGQANSVMSLEHVQVEVSIEYTRRGDLHITLTSPSGTTTVLLAERERDTSSNGFRNWAFMSVHTWGENPTGTWILKITD-----TSGRMENEGQIISWKLILHGTS--EKPEHMKKARVYTPYNAVQ 617
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Match: CR383678.1 (proprotein convertase subtilisin/kexin type 5a [Source:NCBI gene;Acc:571235]) HSP 1 Score: 293.508 bits (750), Expect = 2.593e-84 Identity = 208/533 (39.02%), Postives = 298/533 (55.91%), Query Frame = 3
Query: 639 MNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN--DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRD-TNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHK 2225
+ Q+ ++ + ++Q H+ FNDP+ D +W Y D N DMN+ ++ +G+GVVVS++DDGI+ +H ++ +N+D AS D+N DP DP PRY V +N HGT CA ++A +NN +C +G+A+NA +GG+RML +M TD++EA +L QYIDIYS+SWGP D G + A+E G R+GRKGRGSI+++A+GNGG + DHC DG+ NS YTI+V +T GRKP Y EEC++ T G S P +V + +C + GTSA+ P+ +G IAL LEAN L WRDIQH+ + + + WQ N AG VSH YGFGLL+ A V+NA+ W V +C ++ +I I + R +++GC A + LEHV + I HP RGDL I+LTSP+ T S LL R D ++ I + F++ WGE G W DI D + + +G L+E L +GT+ RH+
Sbjct: 93 IQQQMVQKRVKRTETMDQTHDG----SFNDPKWDSMW----YIHCDH-NCLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDP-----DPT-PRY--DVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDGDM-TDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSG---------DSHSPGVVTTDLRQRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLSASDWQSNGAGYDVSHLYGFGLLNAEAMVKNAETWKQVPSQHICEENIGQNARI--ISPERVLRSVLKSSGCSAQRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSSEGFIKWEFMTTHCWGERSAGDWILDIRDTPS--PQRNTRLQGKLVEWSLVLYGTSTHPYIRHE 594
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Match: pcsk5a (proprotein convertase subtilisin/kexin type 5a [Source:ZFIN;Acc:ZDB-GENE-060531-130]) HSP 1 Score: 291.967 bits (746), Expect = 7.708e-84 Identity = 208/533 (39.02%), Postives = 298/533 (55.91%), Query Frame = 3
Query: 639 MNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN--DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRD-TNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHK 2225
+ Q+ ++ + ++Q H+ FNDP+ D +W Y D N DMN+ ++ +G+GVVVS++DDGI+ +H ++ +N+D AS D+N DP DP PRY V +N HGT CA ++A +NN +C +G+A+NA +GG+RML +M TD++EA +L QYIDIYS+SWGP D G + A+E G R+GRKGRGSI+++A+GNGG + DHC DG+ NS YTI+V +T GRKP Y EEC++ T G S P +V + +C + GTSA+ P+ +G IAL LEAN L WRDIQH+ + + + WQ N AG VSH YGFGLL+ A V+NA+ W V +C ++ +I I + R +++GC A + LEHV + I HP RGDL I+LTSP+ T S LL R D ++ I + F++ WGE G W DI D + + +G L+E L +GT+ RH+
Sbjct: 93 IQQQMVQKRVKRTETMDQTHDG----SFNDPKWDSMW----YIHCDH-NCLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDP-----DPT-PRY--DVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDGDM-TDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSG---------DSHSPGVVTTDLRQRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLSASDWQSNGAGYDVSHLYGFGLLNAEAMVKNAETWKQVPSQHICEENIGQNARI--ISPERVLRSVLKSSGCSAQRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSSEGFIKWEFMTTHCWGERLAGDWILDIRDTPS--PQRNNRLQGKLVEWSLVLYGTSTHPYIRHE 594
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Match: pcsk5a (proprotein convertase subtilisin/kexin type 5a [Source:ZFIN;Acc:ZDB-GENE-060531-130]) HSP 1 Score: 290.426 bits (742), Expect = 5.393e-82 Identity = 208/533 (39.02%), Postives = 298/533 (55.91%), Query Frame = 3
Query: 639 MNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN--DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRD-TNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHK 2225
+ Q+ ++ + ++Q H+ FNDP+ D +W Y D N DMN+ ++ +G+GVVVS++DDGI+ +H ++ +N+D AS D+N DP DP PRY V +N HGT CA ++A +NN +C +G+A+NA +GG+RML +M TD++EA +L QYIDIYS+SWGP D G + A+E G R+GRKGRGSI+++A+GNGG + DHC DG+ NS YTI+V +T GRKP Y EEC++ T G S P +V + +C + GTSA+ P+ +G IAL LEAN L WRDIQH+ + + + WQ N AG VSH YGFGLL+ A V+NA+ W V +C ++ +I I + R +++GC A + LEHV + I HP RGDL I+LTSP+ T S LL R D ++ I + F++ WGE G W DI D + + +G L+E L +GT+ RH+
Sbjct: 72 IQQQMVQKRVKRTETMDQTHDG----SFNDPKWDSMW----YIHCDH-NCLTDMNIQAAWRRGYTGKGVVVSILDDGIERQHPDLKQNYDARASYDVNGNDP-----DPT-PRY--DVTNENKHGTRCAGVVAASANNSLCIVGIAYNAKIGGVRMLDGDM-TDMVEAQSLNLRQQYIDIYSSSWGPDDDGRTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQSQDHCSCDGYTNSIYTISVGSTTQSGRKPWYLEECSSTLATTYSSG---------DSHSPGVVTTDLRQRCTDEHSGTSASAPMAAGIIALTLEANPALTWRDIQHIIVKTSSRGHLSASDWQSNGAGYDVSHLYGFGLLNAEAMVKNAETWKQVPSQHICEENIGQNARI--ISPERVLRSVLKSSGCSAQRLQRVVYLEHVIVRVTITHPHRGDLSITLTSPSGTTSQLLANRPNDHSSEGFIKWEFMTTHCWGERLAGDWILDIRDTPS--PQRNNRLQGKLVEWSLVLYGTSTHPYIRHE 573
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Match: zar1 (zygote arrest 1 [Source:Xenbase;Acc:XB-GENE-942424]) HSP 1 Score: 295.819 bits (756), Expect = 1.255e-87 Identity = 205/552 (37.14%), Postives = 310/552 (56.16%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILK--IRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
++ K +P+ ++S + KR + + +++Y + N+R K FNDP ++ W Y + + P LD++L V+K I+G+GVV++V+DDG++ H +I N+DP AS D ND N DP PRY + +N HGT CA IA +NN CG+GVA+NA +GGIRML +VTD EA ++ N Q++ IYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD +++A ++ +C E GTSA+ PL +G ALALE N L WRD+QHL + P A W+ N AG++V+ R+GFGLL+ A V + + W V + + C+ + N+ +R+ + + T C DN I++LEH+++ IE+ RGDL I+LTSP T +VLL +R RDT+ ++ F+S WGE+P G W I D+ S + G ++ L HGT+
Sbjct: 70 LFRHKAHPRRSRRSAPHLTKRLADDGRVSWAEQQYSKERNKRSTFRQDTKNLFNDPLWNRQW-YLQDTRSNPSLPKLDLHLLPVWKKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDN---DPF-PRY--DITNENRHGTRCAGEIAMVANNNKCGVGVAYNAKVGGIRMLD-GVVTDAKEASSIGFNPQHVHIYSASWGPNDDGKTVEGPGRLAQKAFEYGIKQGRNGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------IISADLHNECTETHTGTSASAPLAAGIFALALEFNPDLTWRDMQHLVVWTSEYDPLANNAGWKKNGAGLMVNSRFGFGLLNAKALVDLADPKTWKGVAEKKECI---VEDNEFSPRFLRSDGEVTIQIPTKACEGQDNHIKSLEHLQLEATIEYTRRGDLHITLTSPLGTNTVLLTERERDTSPYGFKSWDFMSVHTWGEDPAGTWTLKISDV-----SGRKKNEGRIVSWKLILHGTS 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Match: zar1 (zygote arrest 1 [Source:Xenbase;Acc:XB-GENE-942424]) HSP 1 Score: 296.204 bits (757), Expect = 1.289e-87 Identity = 205/552 (37.14%), Postives = 310/552 (56.16%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILK--IRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
++ K +P+ ++S + KR + + +++Y + N+R K FNDP ++ W Y + + P LD++L V+K I+G+GVV++V+DDG++ H +I N+DP AS D ND N DP PRY + +N HGT CA IA +NN CG+GVA+NA +GGIRML +VTD EA ++ N Q++ IYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD +++A ++ +C E GTSA+ PL +G ALALE N L WRD+QHL + P A W+ N AG++V+ R+GFGLL+ A V + + W V + + C+ + N+ +R+ + + T C DN I++LEH+++ IE+ RGDL I+LTSP T +VLL +R RDT+ ++ F+S WGE+P G W I D+ S + G ++ L HGT+
Sbjct: 70 LFRHKAHPRRSRRSAPHLTKRLADDGRVSWAEQQYSKERNKRSTFRQDTKNLFNDPLWNRQW-YLQDTRSNPSLPKLDLHLLPVWKKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDN---DPF-PRY--DITNENRHGTRCAGEIAMVANNNKCGVGVAYNAKVGGIRMLD-GVVTDAKEASSIGFNPQHVHIYSASWGPNDDGKTVEGPGRLAQKAFEYGIKQGRNGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------IISADLHNECTETHTGTSASAPLAAGIFALALEFNPDLTWRDMQHLVVWTSEYDPLANNAGWKKNGAGLMVNSRFGFGLLNAKALVDLADPKTWKGVAEKKECI---VEDNEFSPRFLRSDGEVTIQIPTKACEGQDNHIKSLEHLQLEATIEYTRRGDLHITLTSPLGTNTVLLTERERDTSPYGFKSWDFMSVHTWGEDPAGTWTLKISDV-----SGRKKNEGRIVSWKLILHGTS 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Match: zar1 (zygote arrest 1 [Source:Xenbase;Acc:XB-GENE-942424]) HSP 1 Score: 295.819 bits (756), Expect = 1.348e-87 Identity = 205/552 (37.14%), Postives = 310/552 (56.16%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILK--IRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
++ K +P+ ++S + KR + + +++Y + N+R K FNDP ++ W Y + + P LD++L V+K I+G+GVV++V+DDG++ H +I N+DP AS D ND N DP PRY + +N HGT CA IA +NN CG+GVA+NA +GGIRML +VTD EA ++ N Q++ IYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD +++A ++ +C E GTSA+ PL +G ALALE N L WRD+QHL + P A W+ N AG++V+ R+GFGLL+ A V + + W V + + C+ + N+ +R+ + + T C DN I++LEH+++ IE+ RGDL I+LTSP T +VLL +R RDT+ ++ F+S WGE+P G W I D+ S + G ++ L HGT+
Sbjct: 70 LFRHKAHPRRSRRSAPHLTKRLADDGRVSWAEQQYSKERNKRSTFRQDTKNLFNDPLWNRQW-YLQDTRSNPSLPKLDLHLLPVWKKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDN---DPF-PRY--DITNENRHGTRCAGEIAMVANNNKCGVGVAYNAKVGGIRMLD-GVVTDAKEASSIGFNPQHVHIYSASWGPNDDGKTVEGPGRLAQKAFEYGIKQGRNGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------IISADLHNECTETHTGTSASAPLAAGIFALALEFNPDLTWRDMQHLVVWTSEYDPLANNAGWKKNGAGLMVNSRFGFGLLNAKALVDLADPKTWKGVAEKKECI---VEDNEFSPRFLRSDGEVTIQIPTKACEGQDNHIKSLEHLQLEATIEYTRRGDLHITLTSPLGTNTVLLTERERDTSPYGFKSWDFMSVHTWGEDPAGTWTLKISDV-----SGRKKNEGRIVSWKLILHGTS 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Match: gdap1l1 (ganglioside induced differentiation associated protein 1-like 1 [Source:Xenbase;Acc:XB-GENE-950543]) HSP 1 Score: 290.812 bits (743), Expect = 1.625e-85 Identity = 204/545 (37.43%), Postives = 302/545 (55.41%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAE-RGHLLEVVLEFHGTT----NLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNQQR 2333
FNDP +W + + +MN+ + ++ +G+ VVVS++DDG++ H ++++N+DP AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS+SWGP D G +KA E G ++GRKG GSI+++A+GNGG D+C DG+ NS YTI++++T +G KP Y EECA+ T YS+ ++R +V + C + GTS + P+++G IALALEAN L WRD+QHL + R + W+ N AG VSH YGFGL+D A V A+ W TV VC+G + + IR + R T QT C N + + LEHV + I HP RGDL I L SP+ TKS LL +R D++N + F++ WGE G+W +I D S ++ E +G L E L F+GT+ N +H ++ ++ +P KS ++ ++ +I ++R
Sbjct: 124 FNDPIWPNMWYLHCSDKSSRCRS--EMNVMSAWQRGYTGKNVVVSILDDGVEKNHPDLIQNYDPHASHDVNGDDQ---DP-SPRY--DASNENKHGTRCAGEVAASANNSHCIVGIAYNARIGGIRMLDGD-VTDVVEAKSLGVRPDYIDIYSSSWGPDDDGKTVDGPGPLARKAFEDGIKKGRKGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISISSTTENGYKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQGCTDDHTGTSVSAPMVAGVIALALEANPVLNWRDVQHLLVKTSRSVHLRAPDWKTNGAGRKVSHLYGFGLVDADAMVVEAKKWRTVPPQHVCIGASDRRPRF--IRAVQLIRTTTQTNACVDNAGHYVAYLEHVVVRVTISHPRRGDLQIYLISPSGTKSQLLAKRTFDSSNEGFKNWEFMTVHCWGEKAEGEWTLEIHD---SSSQLRNPEIQGKLKEWTLIFYGTSEHPYNHIGTQHSRIRTLDISATDL---EPSKSTVIQSHLEFIDEEEER 642
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Match: gdap1l1 (ganglioside induced differentiation associated protein 1-like 1 [Source:Xenbase;Acc:XB-GENE-950543]) HSP 1 Score: 290.041 bits (741), Expect = 4.434e-85 Identity = 203/539 (37.66%), Postives = 299/539 (55.47%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAE-RGHLLEVVLEFHGTT----NLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYI 2315
FNDP +W + + +MN+ + ++ +G+ VVVS++DDG++ H ++++N+DP AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS+SWGP D G +KA E G ++GRKG GSI+++A+GNGG D+C DG+ NS YTI++++T +G KP Y EECA+ T YS+ ++R +V + C + GTS + P+++G IALALEAN L WRD+QHL + R + W+ N AG VSH YGFGL+D A V A+ W TV VC+G + + IR + R T QT C N + + LEHV + I HP RGDL I L SP+ TKS LL +R D++N + F++ WGE G+W +I D S ++ E +G L E L F+GT+ N +H ++ ++ +P KS ++ ++ +I
Sbjct: 115 FNDPIWPNMWYLHCSDKSSRCRS--EMNVMSAWQRGYTGKNVVVSILDDGVEKNHPDLIQNYDPHASHDVNGDDQ---DP-SPRY--DASNENKHGTRCAGEVAASANNSHCIVGIAYNARIGGIRMLDGD-VTDVVEAKSLGVRPDYIDIYSSSWGPDDDGKTVDGPGPLARKAFEDGIKKGRKGLGSIFVWASGNGGREGDYCSCDGYTNSIYTISISSTTENGYKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQGCTDDHTGTSVSAPMVAGVIALALEANPVLNWRDVQHLLVKTSRSVHLRAPDWKTNGAGRKVSHLYGFGLVDADAMVVEAKKWRTVPPQHVCIGASDRRPRF--IRAVQLIRTTTQTNACVDNAGHYVAYLEHVVVRVTISHPRRGDLQIYLISPSGTKSQLLAKRTFDSSNEGFKNWEFMTVHCWGEKAEGEWTLEIHD---SSSQLRNPEIQGKLKEWTLIFYGTSEHPYNHIGTQHSRIRTLDISATDL---EPSKSTVIQSHLEFI 627
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Match: Pcsk1 (proprotein convertase subtilisin/kexin type 1 [Source:MGI Symbol;Acc:MGI:97511]) HSP 1 Score: 288.115 bits (736), Expect = 9.163e-85 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S + KR + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY + +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W V + + CV K + + ++ + V T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 69 LFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECV-VKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDM-----SGRMQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Match: Pcsk5 (proprotein convertase subtilisin/kexin type 5 [Source:MGI Symbol;Acc:MGI:97515]) HSP 1 Score: 286.574 bits (732), Expect = 6.583e-83 Identity = 190/501 (37.92%), Postives = 284/501 (56.69%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGL-DMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
FNDP+ +W + D +P DMN+ +K +G+ +VV+++DDGI+ H ++++N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+AFNA +GG+RML + VTD++EA ++++N Q++ IYS SWGP D G ++A E G R GR+G GS++++A+GNGG + DHC DG+ NS YTI++++T G+KP Y EEC++ T YS+ +D+ ++ + +C + GTSA+ P+ +G IALALEAN FL WRD+QH+ + R + W+ N AG VSH YGFGL+D A V A+ W TV Q VCV ++ +I IR R ++ +GC+ N ++ + LEHV + I HP RGDL I LTSP+ T+S LL R+ D + + F++ WGE G W ++ D + G L E L +GT+
Sbjct: 128 FNDPKWPSMWYMHCS---DNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPM--------PRY--DASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGD-VTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATT----YSSGESYDKK-----IITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCV--ESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPS--QLRNFKTPGKLKEWSLVLYGTS 601
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Match: Pcsk6 (proprotein convertase subtilisin/kexin type 6 [Source:MGI Symbol;Acc:MGI:102897]) HSP 1 Score: 282.337 bits (721), Expect = 4.158e-81 Identity = 199/517 (38.49%), Postives = 287/517 (55.51%), Query Frame = 3
Query: 666 KEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCAN-TDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT 2198
+E +R V ++ S S FNDP +W + + +MN+ +K +G+ VVV+++DDGI+ H ++ N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS SWGP D G ++A E G ++GR+G GSI+++A+GNGG DHC DG+ NS YTI+V++T +G KP Y EECA+ T YS+ ++R +V + +C + GTS + P+++G IALALEANN L WRD+QHL + R + + W++N AG VSH YGFGL+D A V A+ W V VCV K + + I + R T T CA+ +D + LEHV + I HP RGDL I L SP+ TKS LL +R+ D +N T + F++ WGE G+W ++ D+ + ++G L E L +GT
Sbjct: 133 QEVKRRVKRQARS-DSLYFNDPIWSNMWYMHCTDKNSRCRS--EMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDP--------SPRY--DASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHVCVATADKRPRSIPIV--QVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPS--QVRNPEKQGKLKEWSLILYGT 622
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Match: Pcsk6 (proprotein convertase subtilisin/kexin type 6 [Source:MGI Symbol;Acc:MGI:102897]) HSP 1 Score: 281.952 bits (720), Expect = 4.849e-81 Identity = 199/518 (38.42%), Postives = 287/518 (55.41%), Query Frame = 3
Query: 666 KEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCAN-TDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
+E +R V ++ S S FNDP +W + + +MN+ +K +G+ VVV+++DDGI+ H ++ N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+A+NA +GGIRML + VTD++EA +L YIDIYS SWGP D G ++A E G ++GR+G GSI+++A+GNGG DHC DG+ NS YTI+V++T +G KP Y EECA+ T YS+ ++R +V + +C + GTS + P+++G IALALEANN L WRD+QHL + R + + W++N AG VSH YGFGL+D A V A+ W V VCV K + + I + R T T CA+ +D + LEHV + I HP RGDL I L SP+ TKS LL +R+ D +N T + F++ WGE G+W ++ D+ + ++G L E L +GT
Sbjct: 133 QEVKRRVKRQARS-DSLYFNDPIWSNMWYMHCTDKNSRCRS--EMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDP--------SPRY--DASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGD-VTDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATT----YSSGAFYERK-----IVTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHVCVATADKRPRSIPIV--QVLRTTALTNACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTNWEFMTVHCWGEKAEGEWTLEVQDIPS--QVRNPEKQGKLKEWSLILYGTA 623
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Match: Pcsk5 (proprotein convertase subtilisin/kexin type 5 [Source:MGI Symbol;Acc:MGI:97515]) HSP 1 Score: 285.804 bits (730), Expect = 2.222e-80 Identity = 184/474 (38.82%), Postives = 275/474 (58.02%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGL-DMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD 2120
FNDP+ +W + D +P DMN+ +K +G+ +VV+++DDGI+ H ++++N+D AS D+N DP PRY + +N HGT CA +A +NN C +G+AFNA +GG+RML + VTD++EA ++++N Q++ IYS SWGP D G ++A E G R GR+G GS++++A+GNGG + DHC DG+ NS YTI++++T G+KP Y EEC++ T YS+ +D+ ++ + +C + GTSA+ P+ +G IALALEAN FL WRD+QH+ + R + W+ N AG VSH YGFGL+D A V A+ W TV Q VCV ++ +I IR R ++ +GC+ N ++ + LEHV + I HP RGDL I LTSP+ T+S LL R+ D + + F++ WGE G W ++ D
Sbjct: 128 FNDPKWPSMWYMHCS---DNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPM--------PRY--DASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGD-VTDMVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATT----YSSGESYDKK-----IITTDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCV--ESTDRQIKTIRPNSAVRSIYKASGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYD 576
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Match: sp|P63239|NEC1_MOUSE (Neuroendocrine convertase 1 OS=Mus musculus OX=10090 GN=Pcsk1 PE=1 SV=1) HSP 1 Score: 288.115 bits (736), Expect = 6.409e-84 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S + KR + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY + +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W V + + CV K + + ++ + V T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 69 LFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECV-VKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDM-----SGRMQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Match: sp|P63240|NEC1_MUSCO (Neuroendocrine convertase 1 OS=Mus cookii OX=10098 GN=Pcsk1 PE=2 SV=1) HSP 1 Score: 288.115 bits (736), Expect = 6.814e-84 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTN-KKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S + KR + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY + +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W V + + CV K + + ++ + V T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 69 LFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECV-VKDNNFEPRALKANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDM-----SGRMQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Match: sp|P29120|NEC1_HUMAN (Neuroendocrine convertase 1 OS=Homo sapiens OX=9606 GN=PCSK1 PE=1 SV=2) HSP 1 Score: 287.73 bits (735), Expect = 8.439e-84 Identity = 200/551 (36.30%), Postives = 308/551 (55.90%), Query Frame = 3
Query: 573 IYATKINPKVHKKS-FTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFK--FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
++ K +P+ ++S F KR + + + +++Y + ++R S FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W +V + + CV K + ++ + + T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 69 LFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQW-YLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECV-VKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDM-----SGRIQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Match: sp|P28840|NEC1_RAT (Neuroendocrine convertase 1 OS=Rattus norvegicus OX=10116 GN=Pcsk1 PE=2 SV=1) HSP 1 Score: 284.648 bits (727), Expect = 1.120e-82 Identity = 195/518 (37.64%), Postives = 291/518 (56.18%), Query Frame = 3
Query: 663 DKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
+KE R+ R +L FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + + W V + + C+ K + + ++ + V T C +N I +LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W + D+ S + G ++ L HGT++
Sbjct: 104 EKERRKRSVPRDSALN--LFNDPMWNQQW-YLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECI-IKDNNFEPRALKANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDM-----SGRMQNEGRIVNWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9GLR1|NEC1_BOVIN (Neuroendocrine convertase 1 OS=Bos taurus OX=9913 GN=PCSK1 PE=2 SV=1) HSP 1 Score: 283.493 bits (724), Expect = 3.259e-82 Identity = 192/501 (38.32%), Postives = 283/501 (56.49%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKI--LKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTN 2204
FNDP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+DP AS D ND + DP PRY + +N HGT CA IA ++NN CG+GVA+N+ +GGIRML +VTD +EA + N ++DIYS SWGP D G QKA E G ++GR+G+GSI+++A+GNGG D+C DG+ +S YTI++ + + G P Y E+C++ T+ G TD + +A ++ C E GTSA+ PL +G ALALEAN L WRD+QHL + P W+ N AG++V+ R+GFGLL+ A V + W++V + + CV K N ++ + + T C +N I++LEHV+ IE+ RGDL ++LTS T +VLL +R RDT+ N + F+S WGENP G W I D+ S + G ++ L HGT++
Sbjct: 121 FNDPMWNQQW-YLQDTRMTATLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDH---DPF-PRY--DLINENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLD-GIVTDAIEASLIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISINSASQQGLSPWYAEKCSSTLATSYSSGDYTDQR---------ITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPSTWSSVPEKKECV---VKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRIADM-----SGRIQNEGRIVTWKLILHGTSS 596
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Match: A0A267G4F6 (P/Homo B domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002511g2 PE=4 SV=1) HSP 1 Score: 361.688 bits (927), Expect = 6.562e-109 Identity = 259/687 (37.70%), Postives = 370/687 (53.86%), Query Frame = 3
Query: 126 LIWFLSTLVAYA------DENLGHNEYAVEM--DMDALEANLDLSANNIEVIRKVSVLGNVYHLKHVHNC--NHA--RCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDP--RGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIP-----NPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIE-HPCRGDLIISLTSPTNTKSVLLKQRVRDTNN--ANITFSFLSQMNWGENPRGKWHFDIVD 2120
L W L+ +++ A E L + +A+E+ + D A +N +++ LGNVYHL+H C NH +C + + ++I + +HP + R QV +VE++ LD +++ + L + +D +D + S D K+R + +ED K Y++ +++RH L NDP + W +N GQ +NPGLD+NL + +G G+VVSV+DDG+D + ++ KN+DP AS D N+ P GP + + HGT CA I +NN CG+GVAFNA LGGIR+L +VTDLLEAYA+ HNNQYI +YS SWGP+D G+ +Y KA+++G +GR G+GS+++ A+GNGG N D+CG DGFVN+P+TIAV A NI GR P Y E C+AI ++A VGG T + D + +NG CF+ GTSAATPL+S C+ALAL+AN L WRD+QHL + S R+P +P WQ+N AG VSH GFGLLDC V AQ W V C K K ++ + K + F + GC T ++ LEHV + ++ RG + I L SP T+S LL R +D +N +FL+ +NW ENP G+W I D
Sbjct: 10 LPWLLACILSCAICVYNCQEQL-TDHFALELLDNSDISVAKEIAKKHNFDLLHHAQQLGNVYHLQHRSACKSNHTANQCATDGA-ALIRSMLSHPRVLRSIHQVAEDVEKR-------------HLD-------IKEFLRNLADGVDDKSDDSSEESRAID-----------------KRR-----EEIEDAKIYKKALSRRHLDL---IVNDPHFNLQWYLHNTGQLQGINPGLDLNLLPAWNRGFTGSGIVVSVVDDGLDPSNPDL-KNYDPLASADFNNLTRKEGIPIRSGPLTMEQT-----HGTACAGEIGALANNSFCGIGVAFNAKLGGIRILD-GVVTDLLEAYAILHNNQYISVYSCSWGPRDNGLVMDMPKFYTSKALQLGVSKGRGGKGSLFVMASGNGGKNADNCGADGFVNNPHTIAVGALNIFGRTPYYGESCSAIHVSAPVGGPHTP---NSKLPDYLVTTTMVNGGCFKEMSGTSAATPLVSSCVALALQANPELSWRDVQHLLSRSARLPSSGKGDPKIQSWQVNGAGHYVSHHAGFGLLDCAKLVFTAQTWPGVTDQIDCRDAKPYRGK-FRVPSRKPLTLPFDSRGCNGT---LKRLEHVLVTLTMQGMAMRGAVEIWLKSPAGTESRLLGMRPKDKDNRVGIKNQTFLTLLNWDENPAGRWLLQIWD 635
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Match: A0A267GWN3 (P/Homo B domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006257g1 PE=4 SV=1) HSP 1 Score: 360.918 bits (925), Expect = 1.486e-108 Identity = 248/641 (38.69%), Postives = 352/641 (54.91%), Query Frame = 3
Query: 240 NNIEVIRKVSVLGNVYHLKHVHNC--NHA--RCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDP--RGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEA-----VWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIE-HPCRGDLIISLTSPTNTKSVLLKQRVRDTNN--ANITFSFLSQMNWGENPRGKWHFDIVD 2120
+N +++ LGNVYHL+H C NH +C + + ++I+ + +HP + R QV +VE++ LD +++ + L + +D +D + S D K+R + +ED K Y++ +++RH L NDP + W +N GQ +NPGLD+NL + +G G+VVSV+DDG+D + ++ KN+DP AS D N+ P GP + + HGT CA I +NN CG+GVAFNA LGGIR+L +VTDLLEAYA+ HNNQYI +YS SWGP+D G+ +Y KA+++G +GR G+GS+++ A+GNGG N D+CG DGFVN+P+TIAV A NI GR P Y E C+AI ++A VGG T + D + +NG CF+ GTSAATPL+S C+ALAL+AN L WRD+QHL + S R+P+ + WQ+N AG VSH GFGLLDC V AQ W V C K K ++ + K + F + GC T ++ LEHV + ++ RG + I L SP T+S LL R +D +N +FL+ +NW ENP G+W I D
Sbjct: 55 HNFDLLHHAQQLGNVYHLQHRSACKSNHTANQCATDGA-ALIQSMLSHPRVLRSIHQVAEDVEKR-------------HLD-------IKEFLRNLADGVDDKSDDSSEESRAID-----------------KRR-----EEIEDAKIYKKALSRRHLDL---IVNDPHFNLQWYLHNTGQLQGINPGLDLNLLPAWNRGFTGSGIVVSVVDDGLDPSNPDL-KNYDPLASADFNNLTRKEGIPIRSGPLTMEQT-----HGTACAGEIGALANNSFCGIGVAFNAKLGGIRILD-GVVTDLLEAYAILHNNQYISVYSCSWGPRDNGLVMDMPKFYTSKALQLGVSKGRGGKGSLFVMASGNGGKNADNCGADGFVNNPHTIAVGALNIFGRTPYYGESCSAIHVSAPVGGPHTP---NSKLPDYLVTTTMVNGGCFKEMSGTSAATPLVSSCVALALQANPELSWRDVQHLLSRSARLPSSGKGDLKIQSWQVNGAGHYVSHHAGFGLLDCAKLVFTAQTWPGVTDQIDCRDAKPYRGK-FRVPSRKPLTLPFDSRGCNGT---LKRLEHVLVTLTMQGMAMRGAVEIWLKSPAGTESRLLGMRPKDKDNRVGIKNQTFLTLLNWDENPAGRWLLQIWD 635
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Match: A0A267G4G7 (P/Homo B domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002511g1 PE=4 SV=1) HSP 1 Score: 360.533 bits (924), Expect = 1.533e-108 Identity = 249/641 (38.85%), Postives = 351/641 (54.76%), Query Frame = 3
Query: 240 NNIEVIRKVSVLGNVYHLKHVHNC--NHA--RCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDP--RGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIP-----NPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIE-HPCRGDLIISLTSPTNTKSVLLKQRVRDTNN--ANITFSFLSQMNWGENPRGKWHFDIVD 2120
+N +++ LGNVYHL+H C NH +C + + ++I+ + +HP + R QV +VE++ LD + + + L + +D +D + S D K+R + +ED K Y++ +++RH L NDP + W +N GQ +NPGLD+NL + +G G+VVSV+DDG+D + ++ KN+DP AS D N+ P GP + + HGT CA I +NN CG+GVAFNA LGGIR+L +VTDLLEAYA+ HNNQYI +YS SWGP+D G+ +Y KA+++G +GR G+GS+++ A+GNGG N D+CG DGFVN+P+TIAV A NI GR P Y E C+AI ++A VGG T + D + +NG CF+ GTSAATPL+S C+ALAL+AN L WRD+QHL + S R+P +P WQ+N AG VSH GFGLLDC V AQ W V C K K ++ + K + F + GC T ++ LEHV + ++ RG + I L SP T+S LL R +D +N +FL+ +NW ENP G+W I D
Sbjct: 55 HNFDLLHHAQQLGNVYHLQHRSACKSNHTANQCATDGA-ALIQSMLSHPRVLRSIHQVAEDVEKR-------------HLD-------INEFLRNLADGVDDKSDDSSEESRAID-----------------KRR-----EEIEDAKIYKKALSRRHLDL---IVNDPHFNLQWYLHNTGQLQGINPGLDLNLLPAWNRGFTGSGIVVSVVDDGLDPSNPDL-KNYDPLASADFNNLTRKEGIPIRSGPLTMEQT-----HGTACAGEIGALANNSFCGIGVAFNAKLGGIRILD-GVVTDLLEAYAILHNNQYISVYSCSWGPRDNGLVMDMPKFYTSKALQLGVSKGRGGKGSLFVMASGNGGKNADNCGADGFVNNPHTIAVGALNIFGRTPYYGESCSAIHVSAPVGGPHTP---NSKLPDYLVTTTMVNGGCFKEMSGTSAATPLVSSCVALALQANPELSWRDVQHLLSRSARLPSSGKGDPKIQSWQVNGAGHHVSHHAGFGLLDCAKLVFTAQTWPGVTDQIDCRDAKPYRGK-FRVPSRKPLTLPFDSRGCNGT---LKRLEHVLVTLTMQGMAMRGAVEIWLKSPAGTESRLLGMRPKDKDNRVGIKNQTFLTLLNWDENPAGRWLLQIWD 635
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Match: A0A1S3HG99 (neuroendocrine convertase 2-like OS=Lingula unguis OX=7574 GN=LOC106155046 PE=3 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 6.512e-97 Identity = 244/681 (35.83%), Postives = 360/681 (52.86%), Query Frame = 3
Query: 276 GNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKS-ENSELEYFY----DDHELD---SDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIY--ATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLND------PRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEEC-AAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT----TNLDSAR-HKNKDLIETYF 2252
G+VYH VH+ R KR A+D ++L +H ++ VE+QV L +++ ELE +D SD +K+ + D+EKE L A D E + + +Y ++ + +K ++ Y T E+D ++ + ++ F DP WQ +N Q G+++N+ +K +G+G VV ++DDG+ +H ++ KN+DP AS D N PR+ VS N HGT CA IA E+NN CG+G+AF+A +GG+R+L VTD LEA A Y+DIYS SWGP+D G Y Q A++ GT +GR GRG+IY++A GNGG D CG DG+V+S YT++V + N +G + E C + +++ + G + +R +V I+G C E F GTS+A PL +GC+ALAL+AN + WRD+QHL + RIPN E W++N AG + ++GFG+LDC V AQ W VG CV K NK KI + +T T+ C NT+N I LEHV ++ ++ RGD+ ++L SP T+S LL R D + I F+F++ NWGENPRG W + D+ G G + L HGT SAR HK++D +++ F
Sbjct: 72 GDVYHF--VHDEIEKRTKR-AADKHRDLLLSHLQVNHVEQQVHLIRDKRDFTPKELEEVLVATIKREAIDNTHSDIEKRRI-DLEKE---KLTARKDRETEEDTRDIVYDKQNELEIETYKDRSVFERHY-----TEENDMAFKDGI-PSPDTEDDMNFIDPLYRDQWQLHN-SQIAGGKKGMNLNVVAAWKKGFTGKGTVVCILDDGVQHEHPDLKKNYDPEASSDFNGNDDDPTPRDDVS--------------NSHGTRCAGEIASEANNSFCGVGIAFDAKIGGVRLLD-GKVTDKLEAKAAIFKMTYVDIYSASWGPRDNGKVMEKPGRYTQAALKEGTSKGRHGRGNIYVWATGNGGHMGDDCGADGYVSSIYTLSVGSINQYGLSTYFMEFCPSTLAVVYSGGKHDPKDRHEREHPILKVVTTDIDGGCTENFQGTSSAAPLCAGCVALALQANQNMTWRDVQHLVVETARIPNFKEPGWEVNGAGKHTNEKFGFGVLDCGKMVEVAQTWKNVGPQHTCVSPMQKENK--KIDSKSTISMTMSTSACQNTENRIDHLEHVEVYVRLNTSRRGDIQLTLISPAGTRSELLSLRPYDDSKKGIDFTFMTVRNWGENPRGTWTLVVKDIPLNGRENT----GEITYWQLILHGTDAKAERGRSARPHKDEDEMQSAF 717
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Match: A0A1S3NW77 (PC3-like endoprotease variant B OS=Salmo salar OX=8030 GN=LOC106581764 PE=3 SV=1) HSP 1 Score: 321.242 bits (822), Expect = 1.374e-92 Identity = 209/553 (37.79%), Postives = 304/553 (54.97%), Query Frame = 3
Query: 669 EYRRLVNQRHESLG-------SFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD----LGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFI 2291
+ R L ++R +SL S FNDP W+ +N+GQ+ + D+N+ V+ NI+G GVVVS+IDDG+D + ++ +NF+ AS DL + DP R +NGHGT CA +A E+NN CG+G+AFNA +GGIR+L VTD +EA +LT NN +ID+Y WGP+D G + A QKA+ +GT++GR G+GSI+++A+GNGG NDHCG DG+VNS Y+IA+ A G+ + E C A+ G +T P + + + C F GTS+A P+ +G +AL LEAN L WRD+QHL ++ ++P+P E W +N AG + RYGFG+LD V+ A + V R C + + I + +G + V Q+ C TD E+ LEHV++ + CRGDL I+L SP T S+LL R D + A + ++ +S +WGE+P G W + D +G C G LL V L +GT N + H + T E+P +SF+
Sbjct: 158 QQRELPSRRQDSLKTEDQLGHSLTFNDPLWPMQWELFNHGQYSSSH--FDLNVMPVWSRNITGNGVVVSIIDDGVDHTNMDLKRNFEAFASFDLRGSHGLSHDPMPLR-----DEENGHGTRCAGEVAMEANNSYCGVGIAFNARIGGIRLLD-GTVTDSMEATSLTFNNDFIDVYVCCWGPRDDGQEMAGPGTLTQKALRLGTQKGRGGKGSIFVWASGNGGLVNDHCGADGYVNSVYSIAIGAVTHMGKPAFFGEPCPAVMAVTLTGASLGNTL-------PLVTVSNLGDGCVTHFAGTSSAAPIAAGILALVLEANPDLTWRDVQHLIAMTAKVPDPKEPGWSVNGAGYHIHDRYGFGVLDAGLMVQQALQFQAVAPHRKCT-QEVTLDPIRILPSGGEVSVNIQSADCLGTDTEVNTLEHVQVKVSLSSVCRGDLSIALVSPAGTVSLLLATRSNDASAAGMRNWTLMSVQSWGEHPHGVWTLKVTDNKGTVGRCVRVSSEEAVGALLSVTLLLYGTYNPHRSLHVCCCIKTT-------EEPLQSFL 687
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Match: pcsk5b (proprotein convertase subtilisin/kexin type 5 [Source:NCBI gene;Acc:103025246]) HSP 1 Score: 297.745 bits (761), Expect = 4.754e-87 Identity = 203/503 (40.36%), Postives = 287/503 (57.06%), Query Frame = 3
Query: 711 SFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
S FND + +W Y + + N DMN+ +K +G+ VVV+++DDGI+ H ++V+N+D AS D+N DP PRY V+ +N HGT CA +A +NN C +G+A+NA +GG+RML + VTD++EA +L+ + Q+IDIYS SWGP D G ++A E G R GRKGRGSI+++A+GNGG + DHC DG+ NS YTI++++T GRKP Y EECA+ T YS+ ++DR ++ + +C + GTSA+ P+ +G IALALEAN L WRD+QH+ + R + W+ N AG VSH YGFGL+D A V+ A+ W V +CV K +I IR R ++ TGC N +N + LEHV + I HP RGDL I+LTSP+ TKS LL R+ D + + F++ WGE G W +I D S+K+ G L E L +GT+
Sbjct: 129 SIFFNDAKWSSMW--YIHCNDNIHNCQSDMNIVGAWKRGYTGKDVVVTILDDGIERNHPDLVQNYDNQASYDVNGNDLDPM--------PRY--DVSNENKHGTRCAGEVAASANNSHCTVGIAYNAKIGGVRMLDGD-VTDMVEAKSLSLHPQHIDIYSASWGPDDDGKTVDGPAALARQAFENGIRLGRKGRGSIFVWASGNGGRSRDHCSCDGYTNSIYTISISSTAESGRKPWYLEECASTLTTT----YSSGENYDRK-----IITTDLRQRCTDSHTGTSASAPMAAGIIALALEANTLLTWRDVQHIIVKTSRAGHLSAPDWKTNAAGYNVSHLYGFGLMDAEAMVKEAERWKPVPPQHICVENADK--QIRTIRPEHVVRSVYKATGCTDNANNHVIYLEHVVVRITITHPRRGDLSINLTSPSGTKSQLLANRLFDHSMEGFKNWEFMTTHCWGEKAAGDWILEINDTPSQLRSQKTP--GKLKEWSLVLYGTS 605
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Match: pcsk5b (proprotein convertase subtilisin/kexin type 5 [Source:NCBI gene;Acc:103025246]) HSP 1 Score: 294.664 bits (753), Expect = 1.031e-83 Identity = 203/503 (40.36%), Postives = 287/503 (57.06%), Query Frame = 3
Query: 711 SFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLN----DPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
S FND + +W Y + + N DMN+ +K +G+ VVV+++DDGI+ H ++V+N+D AS D+N DP PRY V+ +N HGT CA +A +NN C +G+A+NA +GG+RML + VTD++EA +L+ + Q+IDIYS SWGP D G ++A E G R GRKGRGSI+++A+GNGG + DHC DG+ NS YTI++++T GRKP Y EECA+ T YS+ ++DR ++ + +C + GTSA+ P+ +G IALALEAN L WRD+QH+ + R + W+ N AG VSH YGFGL+D A V+ A+ W V +CV K +I IR R ++ TGC N +N + LEHV + I HP RGDL I+LTSP+ TKS LL R+ D + + F++ WGE G W +I D S+K+ G L E L +GT+
Sbjct: 129 SIFFNDAKWSSMW--YIHCNDNIHNCQSDMNIVGAWKRGYTGKDVVVTILDDGIERNHPDLVQNYDNQASYDVNGNDLDPM--------PRY--DVSNENKHGTRCAGEVAASANNSHCTVGIAYNAKIGGVRMLDGD-VTDMVEAKSLSLHPQHIDIYSASWGPDDDGKTVDGPAALARQAFENGIRLGRKGRGSIFVWASGNGGRSRDHCSCDGYTNSIYTISISSTAESGRKPWYLEECASTLTTT----YSSGENYDRK-----IITTDLRQRCTDSHTGTSASAPMAAGIIALALEANTLLTWRDVQHIIVKTSRAGHLSAPDWKTNAAGYNVSHLYGFGLMDAEAMVKEAERWKPVPPQHICVENADK--QIRTIRPEHVVRSVYKATGCTDNANNHVIYLEHVVVRITITHPRRGDLSINLTSPSGTKSQLLANRLFDHSMEGFKNWEFMTTHCWGEKAAGDWILEINDTPSQLRSQKTP--GKLKEWSLVLYGTS 605
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Match: pcsk2 (proprotein convertase subtilisin/kexin type 2 [Source:NCBI gene;Acc:103033370]) HSP 1 Score: 277.715 bits (709), Expect = 4.597e-82 Identity = 194/544 (35.66%), Postives = 290/544 (53.31%), Query Frame = 3
Query: 618 TNKKRYGMNQKTMEDDKEYRRLVNQR---HESLG-------SFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDL--NDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAV--WQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFS---FLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT 2198
T +KR +++ +E D+ + ++ Q + G NDP K W N GQ D PGLD+N+ +K +G+GV ++++DDGID H ++ N++ AS D NDP PRY N HGT CA ++ SNN +CG+GVA+N+ + GIRML +TD++EA +++H Q IDIYS SWGP D G +AM G +GR G+GSIY++A+ GG+ D C DG+ +S +TI++ + GR Y E C++ + G + + ++ D + G C R GTSAA P +G ALALEAN L WRD+QHL ++ + ++ V W+ N G+ +H +G+G+LD V+ AQ W TV + CV G + ++ KI++G+K ++ T C +N ++ LEHV+ + RGDL I++TSP TKS+LL +R RD +A + F F++ WGE+PRG W L E G + + G L E L HGT
Sbjct: 79 TRRKRSLRHRQRLEKDRRVKNVIAQEGFDRQKRGYRDINDIDVSMNDPLFSKQWYLINTGQADGT-PGLDLNVAEAWKMGYTGKGVTIAIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPY------PRYTDDWF--NSHGTRCAGEVSAVSNNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQVIDIYSASWGPTDDGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWAS-GDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTD-------LYGNCTLRHSGTSAAAPEAAGVFALALEANPNLTWRDMQHLTVLTSKRNKLHDEVHQWRRNGVGLEFNHLFGYGVLDAGGMVKLAQDWKTVPERFHCVAGSVQ--EMHKIQSGEKLSLSISTDACQGKENFVRYLEHVQAVVTVNASRRGDLNINMTSPMGTKSILLSRRPRDA-DAKVGFDKWPFMTTHTWGEDPRGTW------LLEVGFQGDAPQSGMLKEWTLMLHGT 596
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Match: pcsk5a (proprotein convertase subtilisin/kexin type 5a [Source:ZFIN;Acc:ZDB-GENE-060531-130]) HSP 1 Score: 281.952 bits (720), Expect = 2.367e-81 Identity = 204/516 (39.53%), Postives = 291/516 (56.40%), Query Frame = 3
Query: 684 VNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRD-TNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHK 2225
+Q H +L FNDP+ +W Y D N DMN+ V++ +G GVVVS++DDG++ H ++ +N+D AS D+N SDP PRY +N HGT CA ++A +NN +C +G+A+NA +GG+RML +M TD++EA +L+ QYIDIYS+SWGP D G + A+E G R+GRKGRGSI+++A+GNGG DHC DG+ NS +TI++ +T GRKP Y EEC++ T G S +V + +C + GTSA+ P+ +G IAL LEAN L WRD+QH+ + R + WQ N AG VSH YGFGL+D A V+ A+ W V VC ++ ++ I K R+ ++++GC A + +EHV I I HP RGDL I+LTSP TKS LL R D + + + + F++ WGE G W +I D S K++ G L+E L F+GT++ RH+
Sbjct: 113 ASQTHSTL----FNDPKWSSMW----YIHCDH-NCLTDMNIKAVWRRGYTGNGVVVSILDDGVERLHPDLKQNYDARASHDVNGND---SDPT-PRY--DATNENKHGTRCAGVVAAAANNSLCMVGIAYNARIGGVRMLDGDM-TDMVEAQSLSLRQQYIDIYSSSWGPDDDGKTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQRKDHCSCDGYTNSIFTISLGSTTQSGRKPWYLEECSSTLATTYSSGESQGLG---------IVTTDLRQRCTDEHSGTSASAPIAAGIIALTLEANPLLTWRDVQHIIVKTSRRGHLSAPDWQSNGAGYDVSHLYGFGLMDAEAMVKEAETWREVPTQHVCEERTVQNARV--ISPEKVLRLLYKSSGCSAQRTQHVAYVEHVIIRVTITHPRRGDLSIALTSPAGTKSQLLALRPNDHSTDGFVKWEFMTTHCWGEKAAGDWILEIRDS---PSLKRNTRPGKLMEWALVFYGTSSHPYQRHE 598
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Match: pcsk5a (proprotein convertase subtilisin/kexin type 5a [Source:ZFIN;Acc:ZDB-GENE-060531-130]) HSP 1 Score: 281.567 bits (719), Expect = 4.514e-80 Identity = 204/516 (39.53%), Postives = 291/516 (56.40%), Query Frame = 3
Query: 684 VNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRD-TNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHK 2225
+Q H +L FNDP+ +W Y D N DMN+ V++ +G GVVVS++DDG++ H ++ +N+D AS D+N SDP PRY +N HGT CA ++A +NN +C +G+A+NA +GG+RML +M TD++EA +L+ QYIDIYS+SWGP D G + A+E G R+GRKGRGSI+++A+GNGG DHC DG+ NS +TI++ +T GRKP Y EEC++ T G S +V + +C + GTSA+ P+ +G IAL LEAN L WRD+QH+ + R + WQ N AG VSH YGFGL+D A V+ A+ W V VC ++ ++ I K R+ ++++GC A + +EHV I I HP RGDL I+LTSP TKS LL R D + + + + F++ WGE G W +I D S K++ G L+E L F+GT++ RH+
Sbjct: 113 ASQTHSTL----FNDPKWSSMW----YIHCDH-NCLTDMNIKAVWRRGYTGNGVVVSILDDGVERLHPDLKQNYDARASHDVNGND---SDPT-PRY--DATNENKHGTRCAGVVAAAANNSLCMVGIAYNARIGGVRMLDGDM-TDMVEAQSLSLRQQYIDIYSSSWGPDDDGKTVDGPGPLARLALENGIRKGRKGRGSIFVWASGNGGQRKDHCSCDGYTNSIFTISLGSTTQSGRKPWYLEECSSTLATTYSSGESQGLG---------IVTTDLRQRCTDEHSGTSASAPIAAGIIALTLEANPLLTWRDVQHIIVKTSRRGHLSAPDWQSNGAGYDVSHLYGFGLMDAEAMVKEAETWREVPTQHVCEERTVQNARV--ISPEKVLRLLYKSSGCSAQRTQHVAYVEHVIIRVTITHPRRGDLSIALTSPAGTKSQLLALRPNDHSTDGFVKWEFMTTHCWGEKAAGDWILEIRDS---PSLKRNTRPGKLMEWALVFYGTSSHPYQRHE 598
BLAST of P/Homo B domain-containing protein vs. Ensembl Sea Lamprey
Match: pcsk2 (proprotein convertase subtilisin/kexin type 2 [Source:ZFIN;Acc:ZDB-GENE-090608-1]) HSP 1 Score: 90.5077 bits (223), Expect = 9.266e-20 Identity = 89/333 (26.73%), Postives = 149/333 (44.74%), Query Frame = 3
Query: 1263 EGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-----------PNPYEAVWQLNTA-----GILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITF---SFLSQMNWGENPRGKWHFDI--VDLGECGSSKKSAERGHLLEVVLEFHGT 2198
+GR G+GS+Y++A+G+GG +D + +S +TI++ + GR Y E C++ + G D + ++ D + G C R GTSAA P +G ALA+EA + ++ L S + P + + T V+ GF L C + Q + R + + + +T T C + ++ LEHV++ + RGDL ++LTSP T+S+LL +R RD+ ++ + F F++ WGE+PRG+W ++ D E ++ +A G L E L HGT
Sbjct: 1 QGRGGKGSVYVWASGDGGSYDDCNCDG-YASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKKDPEAGVATTD-------LYGNCTLRHSGTSAAAPEAAGVFALAIEA------KGVEWLHNTSASVSLLPHSRSQSHPETAPCIARRTTTSDANRAFFVTKSRGF-LGICHDFHLQKQPTTHLTAFR--------GEDVCAVPGQGRLVLTVDTDACEGRADHVRYLEHVQVVVTVNATRRGDLTLNLTSPMGTRSLLLGRRPRDS-DSRVGFHRWPFMTTHTWGEDPRGRWTLEVGFADGAEGPAAAAAARSGVLSEWTLMLHGT 309
BLAST of P/Homo B domain-containing protein vs. Ensembl Sea Lamprey
Match: pcsk7 (proprotein convertase subtilisin/kexin type 7 [Source:ZFIN;Acc:ZDB-GENE-030131-7293]) HSP 1 Score: 85.5001 bits (210), Expect = 1.477e-18 Identity = 86/227 (37.89%), Postives = 124/227 (54.63%), Query Frame = 3
Query: 711 SFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNG-----HGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAV 1376
S FNDP+ K W Q + PG+D+N+ V++ ++G+GVVV+V+DDG++ ++ N+ S DL D DPR P G HGT CA IA +NN +CG+G A+++ + GIR+L +TD +EA A + Q IYS SWGP D G Q A++ G GR+G G+I++ A+GNGG D+C DG+ NS YTI +
Sbjct: 74 SLPFNDPKFPKQWHL----QRNTHTPGMDLNVTGVWERGVTGKGVVVAVVDDGVEHTLPDLQSNYCAEGSYDLTDGDQ---DPR---------PGTGDQESRHGTRCAGEIAAVANNSLCGVGAAYDSRVAGIRLLD-GPLTDHMEATAFNTHYQLNHIYSCSWGPDDDGKTVDGPHVLGQSALQRGVVGGRRGFGTIFVVASGNGGRYQDNCNYDGYANSIYTITI 283
BLAST of P/Homo B domain-containing protein vs. Ensembl Sea Lamprey
Match: pcsk2 (proprotein convertase subtilisin/kexin type 2 [Source:ZFIN;Acc:ZDB-GENE-090608-1]) HSP 1 Score: 67.3958 bits (163), Expect = 3.597e-12 Identity = 41/117 (35.04%), Postives = 66/117 (56.41%), Query Frame = 3
Query: 1863 VTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITF---SFLSQMNWGENPRGKWHFDI--VDLGECGSSKKSAERGHLLEVVLEFHGT 2198
+T T C + ++ LEHV++ + RGDL ++LTSP T+S+LL +R RD+ ++ + F F++ WGE+PRG+W ++ D E ++ +A G L E L HGT
Sbjct: 217 LTVDTDACEGRADHVRYLEHVQVVVTVNATRRGDLTLNLTSPMGTRSLLLGRRPRDS-DSRVGFHRWPFMTTHTWGEDPRGRWTLEVGFADGAEGPAAAAAARSGVLSEWTLMLHGT 332 HSP 2 Score: 50.447 bits (119), Expect = 9.176e-7 Identity = 38/116 (32.76%), Postives = 62/116 (53.45%), Query Frame = 3
Query: 1263 EGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANN 1610
+GR G+GS+Y++A+G+GG +D + +S +TI++ + GR Y E C++ + G D + ++ D + G C R GTSAA P +G ALA+EAN+
Sbjct: 1 QGRGGKGSVYVWASGDGGSYDDCNCDG-YASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKKDPEAGVATTD-------LYGNCTLRHSGTSAAAPEAAGVFALAIEANH 108
BLAST of P/Homo B domain-containing protein vs. Ensembl Yeast
Match: KEX2 (Kexin, a subtilisin-like protease (proprotein convertase); a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway [Source:SGD;Acc:S000005182]) HSP 1 Score: 199.134 bits (505), Expect = 8.774e-54 Identity = 166/502 (33.07%), Postives = 246/502 (49.00%), Query Frame = 3
Query: 699 ESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISG-RIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVR--------NAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLE 2174
E+ NDP ++ W N PG D+N+ +++ NI+G GVV +++DDG+D +++++ NF S D ND N+ P+ PR + HGT CA IA + N CG+GV +NA + GIR+LS ++ T+ EA +L + DIYS SWGP D G + V+KA+ G EGR +G+IY+FA+GNGG D+C DG+ NS Y+I + A + P Y+E C+A+ AV S ++ SS ING+C GTSAA PL +G L LEAN L WRD+Q+L +S + + W+ + G SHRYGFG +D + NAQ W + L V + + + T + + D + +EHV + I+ RG + L SP S L R RD ++ ++F+S +WGEN G W + K+ E GH ++
Sbjct: 126 EAEDKLSINDPLFERQWHLVN-----PSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGSWDFNDNTNL---PK-PRL-----SDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDITTED-EAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVFASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAV---MAVTYSSGSGEYIHSS--------DINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGDWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLESVITISEKSL---------QDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEGFKDWTFMSVAHWGENGVGDWKIKV----------KTTENGHRID 582
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Match: EDO38851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBU0]) HSP 1 Score: 299.671 bits (766), Expect = 9.412e-91 Identity = 199/513 (38.79%), Postives = 290/513 (56.53%), Query Frame = 3
Query: 600 VHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKF----NDPQVDKLWQYYNYGQFDEVNP-GLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLK-QRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVD 2120
VHK ++ +++KT +E L QR L + +DP+ W +N GQ P G+D+++ + NI+GRGVVVS++DDG+D H ++ NFD AS D ND + DPR PR P N HGT CA +A +NN+VCG+GVA+NAN+GG+RML TD+LE +L+ + YIDIYSN WGPKD G Q+A+ G +GR GRG+IY++A GNGG +D C DG+ S YTI++ HG YTE C++ GG + + ++ +V ++ KC E F GTS+A PL +G IAL LEAN L WRD+QHL + ++ +P + W N AG +H++GFG LD A V+ A+ W +V R+C G + + + +I TG +T T C+ TD + LEHV + +H RGD+ I L SP+ T++ +L +R D+ N ++F++ NWGENP+G+W ++ D
Sbjct: 45 VHKPGNRARRELHVHEKTRLLMQEDEVLWAQRQHVLARTRKYIVPHDPKFHDQWYLFNDGQ--STGPAGVDIDVVPAWNRNITGRGVVVSILDDGVDHTHPDLRDNFDQKASYDFND---MDPDPR-PR---DSDPDNCHGTRCAGEVAA-ANNDVCGVGVAYNANIGGVRMLD-GQATDVLEGSSLSFQSAYIDIYSNCWGPKDDGKTFGKPGKLAQEALMQGALKGRGGRGNIYVWATGNGGLTDDDCNCDGYTTSIYTISIGCIGDHGLSAYYTELCSSTLGVTFNGGSHREREENK------MVTTDLHHKCTEEFKGTSSAAPLAAGMIALVLEANPNLSWRDVQHLVVETAQVTSPVDEGWMKNGAGYHFNHKFGFGRLDADAMVKRAKTWKSVAPQRICHGPSSSTQQ--EIPTGGTLSITIDTIACSGTDKMLTKLEHVTLTVSFQHRRRGDVSIDLFSPSGTRNEMLSTRRYDDSKNGLHDWTFMTVHNWGENPKGEWVMNVTD 538
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Match: EDO47748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT1]) HSP 1 Score: 291.197 bits (744), Expect = 7.461e-88 Identity = 206/534 (38.58%), Postives = 295/534 (55.24%), Query Frame = 3
Query: 645 QKTMEDDKEYRRLVNQRHESLGSF-KFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFT-ISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANIT-FSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNK 2231
++ E +E R + R + G +F DP D W Y + LD+++ V+K ISG+GVVV+++DDGI+ H +++KN+DP AS D+ND N DP PRY +N HGT CA +A E+NN CG+GVAFNA +GG+RML VTD +EA +L+ N QYIDIYS SWGP D G A G ++GR G GSI+++A+GNGG + D C DG+ +S YT+++++ + HG P Y+E C++ T G + +V ++ C ER GTSA+ PL +G ALALE N L WRD+QH+ S +P ++ W N ++V+ ++GFGLL V N + TV + R C G + K+ K K + TGC+ T +EI+ LEHV++ +++ RGDL+I LTSP TKS LL R D++N + + F++ +WGE+PRG W +I DLG+ A G L E L HGT D H+ K
Sbjct: 110 EQQHEKVREKRGFYHDRMVARGIVPRFKDPLWDAQW----YLDDKRKDTDLDIHVIPVWKKGISGKGVVVTILDDGIEHNHTDLIKNYDPNASWDVNDGDN---DPF-PRY--DPTNENKHGTRCAGEVAAEANNTKCGVGVAFNARIGGVRMLD-GRVTDKVEAESLSLNPQYIDIYSASWGPSDDGATVEGPGTLATAAFLNGIQKGRGGLGSIFVWASGNGGRHGDSCNCDGYTDSIYTLSISSASDHGESPWYSESCSSTLATTFSSGAHGEKR---------IVTTDLHNTCTERHTGTSASAPLAAGIFALALEVNPKLTWRDMQHIVVHTSNHLPLKHDQDWSKNGIDLMVNRKFGFGLLVAEKIVDMANPATYVTVPEKRFCRGQINQDAKVFKWD--KPLTIQLPATGCSGTGDEIRYLEHVQLMVSLDYVRRGDLVIYLTSPMGTKSCLLSPRKEDSSNEGFSKWPFMTTHSWGEDPRGTWTLEIKDLGD-----NKANHGTLREWQLILHGTK--DKPAHQQK 614
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Match: EDO38852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBU1]) HSP 1 Score: 286.96 bits (733), Expect = 3.468e-86 Identity = 190/503 (37.77%), Postives = 276/503 (54.87%), Query Frame = 3
Query: 726 DPQVDKLWQYYNYGQFDEVNP-GLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD--LGECGSSKKSAERGHLLEVVLEFHGTTNLDSARH 2222
DP ++W N GQ P G+D+N+ V+K I+GRGVVV+V+DDG+D H ++ N++P AS D ND DP PR I P N HGT CA IA +N+ +CG GVA+NA +GG+RML TD LEA +L NQ D+YSN WGPKD G KA++ G +GR G+G+I+++A GNGG +D C DG+ S YT+++ HG YTE C++ GG + + ++ ++ + GKC E+F GTS+A PL +G +AL LE N L WRD+QH+ + ++ +P + W+ N AG+ +H++GFG LD A V +++W V R C G + + I G + T GC T EI LEHV + H RGD+ + LTSP+ TK+ +L R D + + +SF++ WGENPRG W +++D L E G + V+ GT +LD+++
Sbjct: 92 DPMFTEMWYLMNTGQTG--GPVGVDINVIPVWKRGITGRGVVVTVLDDGMDHNHPDLKPNYEPCASHDFNDND---QDP-APRDID---PDNCHGTRCAGEIAAVANDSICGAGVAYNAKIGGVRMLD-GKATDALEACSLGFANQVTDVYSNCWGPKDDGKTFGKPGPLAAKALKSGAEKGRGGKGNIFVWATGNGGLTDDDCNCDGYTTSIYTVSIGCIGDHGLSAYYTELCSSTLAVTFNGGAHREKEENK------MITTDLKGKCTEQFKGTSSAAPLAAGMVALMLEQNPSLTWRDVQHIIVHTAKMTSPVDDGWRTNGAGLHFNHKFGFGRLDADAMVEKSRVWKNVPVQRTCTGASSVTGDEKDIPVGGSLDIQIPTGGCMGTIAEINHLEHVVLTVSFIHRRRGDVSLLLTSPSGTKNEMLSTRRYDDSKEGLDKWSFMTVHCWGENPRGFWKLNVIDNPLNEIG------------DRVVNGFGTLHLDTSKQ 566
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Match: EDO40864 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S624]) HSP 1 Score: 272.322 bits (695), Expect = 1.717e-81 Identity = 182/471 (38.64%), Postives = 258/471 (54.78%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSV--DPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVC-VGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD 2120
+NDP + W ++G+ + V DM + + + A+ +V + D + +K++DP ASL+LN N D G I R P HGT CA I +SNN CG+GVA + NLG IRML VT + E +A +HN QY+DIYS SWGPKD G A + +KA+E G + GR G+GS+Y++A+GNGG ++D C DG+ +S YTIAV + + G Y E+C S A V YS D+D R+ + + LV + C E F GTSAA PL +G +AL L+AN L WRD+QHL T S + W+ N AG LVS+++GFGLL+ NA W V + C + G + I+ K+ + +T GC ++N I+ LEHV+ + H RG L I + SP T S LL R D + + I + F++ WGE+P+G+W I D
Sbjct: 93 YNDPMLQDQWYLKSFGR-NGVPMNNDMKVMDAW-ADGYTGKGIVVTVMDDGLDHTNDDLKHYDPKASLNLNGATN--GDTTGKDPIPRDEPDQYHGTKCAGEIGAKSNNGFCGVGVAPDVNLGAIRMLD-GKVTGMTEGHAFSHNPQYVDIYSASWGPKDNGKTLAGPSSLGRKALEHGVKRGRNGKGSLYVWASGNGGASSDDCNCDGYTSSIYTIAVGSVSAAGGSTFYDEKCP--STLAVV--YSGDSDLSRTKLGGNHKLVTTGPHNSCVEHFGGTSAAAPLAAGVVALTLQANPELTWRDMQHLITRSTDQLQKDDPSWKRNAAGFLVSNKFGFGLLNAHKLTTNALKWKRVPDQKRCEIEGPIPP--VPLIKRNKEVVLRVRTNGCEGSENAIKRLEHVQAIITLAHRKRGVLSIDIRSPRKTASRLLSTRPLDESASGIKNWPFMTVQMWGEDPKGEWEVVIRD 552
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Match: EDO33327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSI6]) HSP 1 Score: 271.937 bits (694), Expect = 5.209e-81 Identity = 197/486 (40.53%), Postives = 276/486 (56.79%), Query Frame = 3
Query: 684 VNQRHESLGSFK----FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDP-CLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVC-VGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVD 2120
+Q+ SLG + ++DP K W N GQF+ + G D+ + V++ +G+GVVVS++DDG+D H ++ +N+DP AS D ND + DP + V P N HGT C + +++N++CG GVA N +LGGIRML + TD LEA AL++ QYIDIYSN WGPKD G QKA+E G ++GR G+GSIY++A GNGG +D C DG+ +S YTI++ A + +G Y E+C++ G D RS + LV ++ +C + F GTS+A PL +G AL LEAN L WRD+QHL S +P + W++N AGI +H++GFG L T V NA W V +C V G +I+K R GK + T GCA T N ++ LEHV+ ++H RG L I + SP T S LL R DT+ N +SF++ WGE+P G+W I D
Sbjct: 91 ASQQQRSLGHERRKRFYHDPMFAKQWYLQNTGQFN-IPEGNDIGVLPVWERGFTGKGVVVSILDDGLDHTHPDLKRNYDPKASWDFNDKDD---DP----FPNDVDPYNAHGTKCGGEVGAQADNDICGAGVAPNVSLGGIRMLD-GVATDALEANALSYKPQYIDIYSNCWGPKDDGKTFGRPGKLGQKALEDGAKKGRGGKGSIYVWATGNGGLVDDDCNCDGYTSSIYTISIGAISSYGLSTYYDEQCSSTMAVTFTG------DSHRSGEEEYTLVTTNLHHECTDTFRGTSSAAPLAAGIFALVLEANPNLTWRDLQHLVVHSAEKTSPLDQGWKVNGAGIHFNHKFGFGRLHATRLVANALKWKHVPAQHICQVEGFQARKEIIK-RNGKLI-LKVHTDGCAGTKNAVKRLEHVQATVSLKHNRRGALSIEIRSPMGTTSQLLSTRKYDTSTNGLKDWSFMTVHFWGEDPAGEWEVIITD 559
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000002776.2 (proprotein convertase subtilisin/kexin type 4-like [Source:NCBI gene;Acc:101161187]) HSP 1 Score: 290.812 bits (743), Expect = 1.167e-88 Identity = 174/444 (39.19%), Postives = 247/444 (55.63%), Query Frame = 3
Query: 885 KEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAI-SITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD----LGECGSSKKSAERGHLLEVVLEFHGT 2198
K++ KNF+ AS DL + DP + +N HGT CA ++ E+NN CG+G+AFNA +GGIR+L VTD +EA ALT+N +IDIY SWGP+D G + Y ++A+ +GTR+GR G+GSI+++AAGNGG +DHCG DG++NS YTI++ A G+ + E CA + ++T GY D+ P + C F GTS+A P+ +G +ALALE N L WRD+QHL + +IP+P E W +N AG V HRYGFG+LD V+ A ++ VG+ R C + + G + + GC T NEI +LEHV++ + CRGDL +SL SP T S+LL R D + A + ++ ++ WGE PRG W + D + C + G LL L +GT
Sbjct: 27 KDLRKNFEVFASFDLLASHGLSHDPMPIK-----DEENSHGTRCAGEVSMEANNSYCGVGIAFNAKIGGIRLLD-GPVTDAMEASALTYNIHFIDIYVCSWGPRDNGAEMDGPHYLTEQALRLGTRKGRVGKGSIFVWAAGNGGMYDDHCGADGYINSIYTISIGAITQSGKPAFFGEPCAGVMAVTPTGSGYG---DYQ-----PLVTLTTTGDGCVTHFPGTSSAAPIAAGILALALEVNPALTWRDVQHLIANTAKIPDPEEPGWSINAAGYHVHHRYGFGVLDAGLLVQQAALFQKVGRQRTCT-QEVAFDSPRIFSPGDSVTLRIHSDGCQWTSNEISSLEHVQVRLGVSARCRGDLSVSLESPGGTVSMLLDSRPNDASTAGLKNWTLMTVHCWGEQPRGHWTLKVTDHKGEVWRCTRQHEEEPAGALLTATLILYGT 455
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044769.1 (proprotein convertase subtilisin/kexin type 4-like [Source:NCBI gene;Acc:101161187]) HSP 1 Score: 292.738 bits (748), Expect = 2.502e-88 Identity = 174/444 (39.19%), Postives = 247/444 (55.63%), Query Frame = 3
Query: 885 KEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAI-SITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDIVD----LGECGSSKKSAERGHLLEVVLEFHGT 2198
K++ KNF+ AS DL + DP + +N HGT CA ++ E+NN CG+G+AFNA +GGIR+L VTD +EA ALT+N +IDIY SWGP+D G + Y ++A+ +GTR+GR G+GSI+++AAGNGG +DHCG DG++NS YTI++ A G+ + E CA + ++T GY D+ P + C F GTS+A P+ +G +ALALE N L WRD+QHL + +IP+P E W +N AG V HRYGFG+LD V+ A ++ VG+ R C + + G + + GC T NEI +LEHV++ + CRGDL +SL SP T S+LL R D + A + ++ ++ WGE PRG W + D + C + G LL L +GT
Sbjct: 27 KDLRKNFEVFASFDLLASHGLSHDP-----MPIKDEENSHGTRCAGEVSMEANNSYCGVGIAFNAKIGGIRLLD-GPVTDAMEASALTYNIHFIDIYVCSWGPRDNGAEMDGPHYLTEQALRLGTRKGRVGKGSIFVWAAGNGGMYDDHCGADGYINSIYTISIGAITQSGKPAFFGEPCAGVMAVTPTGSGYG---DYQ-----PLVTLTTTGDGCVTHFPGTSSAAPIAAGILALALEVNPALTWRDVQHLIANTAKIPDPEEPGWSINAAGYHVHHRYGFGVLDAGLLVQQAALFQKVGRQRTCT-QEVAFDSPRIFSPGDSVTLRIHSDGCQWTSNEISSLEHVQVRLGVSARCRGDLSVSLESPGGTVSMLLDSRPNDASTAGLKNWTLMTVHCWGEQPRGHWTLKVTDHKGEVWRCTRQHEEEPAGALLTATLILYGT 455
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Match: pcsk1 (proprotein convertase subtilisin/kexin type 1 [Source:NCBI gene;Acc:101174018]) HSP 1 Score: 286.96 bits (733), Expect = 2.474e-84 Identity = 187/499 (37.47%), Postives = 288/499 (57.72%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRG-PRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRI-PNPYEAVWQLNTAGILVSHRYGFGLLDCTAYV--RNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTN-NANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTT 2201
F+DP ++ W Y + P LD+++ V++ I+G+GVV++V+DDG++ H +I N+D AAS D ND +DP PRY + +N HGT CA IA +++N CG+GVA+N+ +GGIRML +VTD +EA ++ N ++DIYS SWGP D G QKA E G ++GR G+GSI+++A+GNGG D+C DG+ +S YTI++++ + G P Y E+C++ TA G TD + +A ++ +C + GTSA+ PL +G ALALE N L WRD+QH+ + P W+ N AG++V+ R+GFGLL+ A V + W V + ++C+ + S + +++ + + T CA +N +++LEH+++ IE+ RGDL I+LTSP T +VLL +R RDT+ N + F+S WGE+P G W I D +S + +G +L L HGT+
Sbjct: 127 FDDPMWNQQW-YLQDTRTSSSLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYSNYDAAASYDFND-----NDPDPFPRYDS--TNENKHGTRCAGEIAMQADNNKCGVGVAYNSKVGGIRMLD-GIVTDAIEASSIGFNPNHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGIQKGRGGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATAYSSGDYTDQR---------ITSADLHNECTQTHTGTSASAPLAAGIFALALEQNPNLTWRDLQHIIVWTSEFDPLANNPGWKRNGAGLMVNSRFGFGLLNAKALVDLADPATWKHVPEKKICI-VRDDSFQPRELKAAGEITIEIPTKACAGQENAVRSLEHLQVEASIEYTRRGDLHITLTSPAGTTTVLLAERERDTSANGFRNWDFMSVHTWGEDPAGTWTLKITD-----TSGRMENKGRILSWKLILHGTS 601
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Match: pcsk2 (proprotein convertase subtilisin/kexin type 2 [Source:NCBI gene;Acc:100049241]) HSP 1 Score: 266.929 bits (681), Expect = 9.424e-79 Identity = 182/500 (36.40%), Postives = 269/500 (53.80%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDL--NDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAV--WQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFS---FLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT 2198
+DP K W N GQ D PGLD+N+ ++ +G+GV ++++DDGID H ++ N++ AS D NDP PRY N HGT CA ++ +NN +CG+GVA+N+ + GIRML +TD++EA +++H Q IDIYS SWGP D G +AM G +GR G+GSIY++A+ GG+ D C DG+ +S +TI++ + GR Y E C++ + G + + ++ D + G C R GTSAA P +G ALALEAN L WRD+QHL ++ + ++ V W+ N G+ +H +G+G+LD V+ A+ W TV + CV G + KI++G K + T C DN ++ LEHV+ + RGDL I++TSP TKS+LL +R RD +++ + F F++ WGE+PRG W E G +RG L E + HGT
Sbjct: 63 MSDPLFTKQWYLINTGQADGT-PGLDLNVAEAWQLGYTGKGVTIAIMDDGIDYLHPDLASNYNADASYDFSSNDPFPF------PRYTDDWF--NSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQTIDIYSASWGPTDDGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWAS-GDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTD-------LYGNCTLRHSGTSAAAPEAAGVFALALEANPNLTWRDMQHLSVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGGMVKMAKEWKTVPERFHCVAGSIQEPH--KIQSGNKLVLAINTEACEGKDNFVRYLEHVQAVVTVNATRRGDLNINMTSPMGTKSLLLSRRPRD-DDSKVGFDKWPFMTTHTWGEDPRGTWVL------EVGFQGDQPQRGVLKEWTVMLHGT 536
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Match: pcsk2 (proprotein convertase subtilisin/kexin type 2 [Source:NCBI gene;Acc:100049241]) HSP 1 Score: 267.314 bits (682), Expect = 2.965e-78 Identity = 182/500 (36.40%), Postives = 269/500 (53.80%), Query Frame = 3
Query: 720 FNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDL--NDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAV--WQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFS---FLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT 2198
+DP K W N GQ D PGLD+N+ ++ +G+GV ++++DDGID H ++ N++ AS D NDP PRY N HGT CA ++ +NN +CG+GVA+N+ + GIRML +TD++EA +++H Q IDIYS SWGP D G +AM G +GR G+GSIY++A+ GG+ D C DG+ +S +TI++ + GR Y E C++ + G + + ++ D + G C R GTSAA P +G ALALEAN L WRD+QHL ++ + ++ V W+ N G+ +H +G+G+LD V+ A+ W TV + CV G + KI++G K + T C DN ++ LEHV+ + RGDL I++TSP TKS+LL +R RD +++ + F F++ WGE+PRG W E G +RG L E + HGT
Sbjct: 123 MSDPLFTKQWYLINTGQADGT-PGLDLNVAEAWQLGYTGKGVTIAIMDDGIDYLHPDLASNYNADASYDFSSNDPFPF------PRYTDDWF--NSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQTIDIYSASWGPTDDGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWAS-GDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTD-------LYGNCTLRHSGTSAAAPEAAGVFALALEANPNLTWRDMQHLSVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGGMVKMAKEWKTVPERFHCVAGSIQEPH--KIQSGNKLVLAINTEACEGKDNFVRYLEHVQAVVTVNATRRGDLNINMTSPMGTKSLLLSRRPRD-DDSKVGFDKWPFMTTHTWGEDPRGTWVL------EVGFQGDQPQRGVLKEWTVMLHGT 596
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Match: SMESG000074551.1 (SMESG000074551.1) HSP 1 Score: 1584.7 bits (4102), Expect = 0.000e+0 Identity = 794/810 (98.02%), Postives = 798/810 (98.52%), Query Frame = 3
Query: 108 MEFYYLLIWFLSTLVAYADENLGHNEYAVEMDMDALEANLDLSANNIEVIRKVSVLGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLV-----AAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNQQRKYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 2522
MEFYYLLIWFLSTLVAYADENLGHNEYAVEMDMDALEANLDLSANNIEVIRKVS LGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKP+SEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYR LVNQRHE LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCG GVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCL+ +INGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFN+QR YFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL
Sbjct: 1 MEFYYLLIWFLSTLVAYADENLGHNEYAVEMDMDALEANLDLSANNIEVIRKVSALGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPASEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRGLVNQRHEGLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGFGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLIVLILGGGKINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNRQRNYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 810
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Match: SMESG000074551.1 (SMESG000074551.1) HSP 1 Score: 1521.52 bits (3938), Expect = 0.000e+0 Identity = 764/780 (97.95%), Postives = 768/780 (98.46%), Query Frame = 3
Query: 198 MDMDALEANLDLSANNIEVIRKVSVLGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLV-----AAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNQQRKYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 2522
MDMDALEANLDLSANNIEVIRKVS LGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKP+SEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYR LVNQRHE LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCG GVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCL+ +INGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFN+QR YFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL
Sbjct: 1 MDMDALEANLDLSANNIEVIRKVSALGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPASEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRGLVNQRHEGLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGFGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLIVLILGGGKINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNRQRNYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 780
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Match: SMESG000074551.1 (SMESG000074551.1) HSP 1 Score: 1517.29 bits (3927), Expect = 0.000e+0 Identity = 762/778 (97.94%), Postives = 766/778 (98.46%), Query Frame = 3
Query: 204 MDALEANLDLSANNIEVIRKVSVLGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPSSEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLV-----AAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNQQRKYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 2522
MDALEANLDLSANNIEVIRKVS LGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKP+SEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYR LVNQRHE LGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCG GVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCL+ +INGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFN+QR YFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL
Sbjct: 1 MDALEANLDLSANNIEVIRKVSALGNVYHLKHVHNCNHARCKREASDSIIEILKNHPMIHRVEEQVDLEVEQKSENSELEYFYDDHELDSDTQKKVLEDVEKELVNDLDADTDMEKKPASEFDIYATKINPKVHKKSFTNKKRYGMNQKTMEDDKEYRGLVNQRHEGLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANISGRGVVVSVIDDGIDTKHKEIVKNFDPAASLDLNDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGFGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAGNGGGNNDHCGGDGFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLIVLILGGGKINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGTTNLDSARHKNKDLIETYFKNIHLEQPKKSFILNANQTYIYFNRQRNYFIQLHPINQKVIQYRDRIRKLKSPEQWETISKEINELNYIIPDDEKNYLNNLLHNRKHNTL 778
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Match: SMESG000049794.1 (SMESG000049794.1) HSP 1 Score: 244.588 bits (623), Expect = 4.076e-70 Identity = 187/530 (35.28%), Postives = 282/530 (53.21%), Query Frame = 3
Query: 573 IYATKINPKVHKKSFTNKKRYGMNQKTMEDD-------KEYRRLVNQRHESLGSFKFNDPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDL----NDPRNVVSDPRGPRYITRVAPK---NGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAVWQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGCA-NTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNANI-TFSFLSQMNWGENPRGKWHFDI 2114
IY+ K + +V K+S Y Q + DD +++ ++ +RH NDP+ K+W +++N MN+ + +K G+ VVVS++DDGI+ H ++ +N+DP AS D+ N+P PRYI+ K N HGT CA +A +NN +CG+GVA+ AN+GGIRML V+D +E+++L Q+IDIYS SWGP+D G + A E G +GR G GSI+++A+GNGG N+D+C DG+ NS +T+ V A + G P Y E+C++ T AV YS+ + +R+ ++ +N +C E+ GTSA+ P +G ALAL AN FL WRD+QHL I+ R N W N AG SH +GFGL+D A V A W TV + +C + ++ ++ T C+ N+ ++ LEHV+ + RG++ + L SP+ + S LL +R D +A + F+S WGE G W I
Sbjct: 60 IYSFK-HRRVSKRSIYPSNYY---QSNLSDDPRVIWLEQQFAKVRVKRH------IVNDPKWYKMWY------LNKMNKENSMNIISAWKKGYRGQNVVVSILDDGIEKDHPDLKENYDPNASYDIISNDNNPE--------PRYISSNNTKIKDNHHGTRCAGQVAATANNRICGVGVAYKANIGGIRMLD-GEVSDSVESHSLRLFYQHIDIYSASWGPEDDGKTVDGPGELAKIAFEDGILKGRNGLGSIFVWASGNGGKNHDNCNCDGYTNSIFTLGVNAVSEIGDAPWYAEKCSS---TLAVT-YSSGSMDERA-----IITTDVNHECTEQHSGTSASAPFAAGICALALSANRFLTWRDMQHLVVITARKANLRAVDWSTNAAGKEYSHSFGFGLMDAGAMVDLALNWTTVPEQHICHYVAPMQGGPISLKPYANEVLSITTDACSDNSKKRVRYLEHVQAKISLRSTKRGEVELWLISPSRSTSKLLTKRRNDVASAGFHHWPFMSVHFWGEEAPGTWKLTI 555
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Match: SMESG000008070.1 (SMESG000008070.1) HSP 1 Score: 243.817 bits (621), Expect = 9.274e-70 Identity = 171/500 (34.20%), Postives = 265/500 (53.00%), Query Frame = 3
Query: 726 DPQVDKLWQYYNYGQFDEVNPGLDMNLFNVYKANXXXXXXXXXXXXXXXXTKHKEIVKNFDPAASLDL--NDPRNVVSDPRGPRYITRVAPKNGHGTLCASIIAGESNNEVCGLGVAFNANLGGIRMLSLNMVTDLLEAYALTHNNQYIDIYSNSWGPKDTGMKTAPVTYYVQKAMEIGTREGRKGRGSIYLFAAXXXXXXXXXXXXXXFVNSPYTIAVTATNIHGRKPAYTEECAAISITAAVGGYSTDTDFDRSSVDPCLVAAQINGKCFERFVGTSAATPLISGCIALALEANNFLGWRDIQHLFTISGRIPNPYEAV----WQLNTAGILVSHRYGFGLLDCTAYVRNAQMWNTVGQLRVCVGGKTKSNKILKIRTGKKTRVTFQTTGC-ANTDNEIQALEHVRIHTKIEHPCRGDLIISLTSPTNTKSVLLKQRVRDTNNAN--ITFSFLSQMNWGENPRGKWHFDIVDLGECGSSKKSAERGHLLEVVLEFHGT 2198
DP K W N GQ D V LD+N+ + + I+G+GV +++DDGID H ++ KN++ +S D NDP PRY N HGT CA I+ E +N +CG+GVA+++ + G+RML +TDL+EA A++++ IDIYS SWGP D G +A+ G +GRKG+GSIY++A+ GG D C DG+ S +TI++ + G +Y E C++ + G + S+D + + G+C GTSAA P +G ALALEAN+ +GWRD+QHL ++ + + ++ W +N AG+ +H +G+G+LD VR A+ W V + C+ G+ +K + K + T C ++ + + LEHV+ ++ RGD+ + LTSP T S++L R +D ++ + F++ WGENPRGKW ++ +K +G E VL HGT
Sbjct: 140 DPLFSKEWYIRNTGQADGVKD-LDLNVLSAWAQGITGKGVTTAIMDDGIDYLHPDLSKNYNAESSYDFSSNDPYPF------PRYTDDWF--NSHGTRCAGEISAERDNGICGVGVAYDSKIAGLRMLDQPYMTDLIEAAAMSYDRDNIDIYSASWGPTDDGRTVDGPRNETMRAIVEGVNKGRKGKGSIYVWAS-GDGGAADDCNCDGYAASMWTISINSATNDGETASYDESCSSTLASTFSNGKAW------FSLDAGVGTVDLYGQCTLHHSGTSAAAPEAAGVFALALEANSNIGWRDMQHLTVLTSKRNHLHDRDRRHNWTINGAGLEFNHLFGYGVLDAGDMVRVAKKWVNVPERFHCIAGQI--DKRYRFNVTKALILEIDTDACKSDIGHRVNYLEHVQAFVSVKSSRRGDITMFLTSPMGTTSMILSHRPKDDDSTRGFTKWPFMTTHTWGENPRGKWKLTVM-----FDTKDPLSQGIFSEWVLVLHGT 616 The following BLAST results are available for this feature:
BLAST of P/Homo B domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of P/Homo B domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of P/Homo B domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of P/Homo B domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001371 ID=SMED30001371|Name=P/Homo B domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2594bpback to top protein sequence of SMED30001371-orf-1 >SMED30001371-orf-1 ID=SMED30001371-orf-1|Name=SMED30001371-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=806bp MEFYYLLIWFLSTLVAYADENLGHNEYAVEMDMDALEANLDLSANNIEVIback to top Annotated Terms
The following terms have been associated with this transcript:
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