Carbonic anhydrase-related

Overview


Name	Carbonic anhydrase-related
Smed ID	SMED30001341
Length (bp)	1209

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Carbonic anhydrase-related (SMED30001341) t-SNE clustered cells

Violin plots show distribution of expression levels for Carbonic anhydrase-related (SMED30001341) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Carbonic anhydrase-related (SMED30001341) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Carbonic anhydrase-related (SMED30001341) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001341

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30001341	h1SMcG0004357	dd_Smed_v4_10750_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30001341	h1SMcG0004357	dd_Smed_v4_10750_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30001341	h1SMcG0004357	dd_Smed_v4_10750_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30001341	h1SMcG0004357	dd_Smed_v6_10750_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
head region	SMED30001341	h1SMcG0004357	dd_Smed_v6_10750_1_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
reproductive organ	SMED30001341	h1SMcG0004357	Contig5200	GPL15192	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30001341	h1SMcG0015254	Contig5200	GPL15192	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Carbonic anhydrase-related vs. Ensembl Human
Match: CA10 (carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC:1369])

HSP 1 Score: 196.438 bits (498), Expect = 4.917e-59
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. Ensembl Human
Match: CA10 (carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC:1369])

HSP 1 Score: 168.703 bits (426), Expect = 5.997e-49
Identity = 92/266 (34.59%), Postives = 141/266 (53.01%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASK 988
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  ++
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQ 274

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BLAST of Carbonic anhydrase-related vs. Ensembl Human
Match: CA11 (carbonic anhydrase 11 [Source:HGNC Symbol;Acc:HGNC:1370])

HSP 1 Score: 166.777 bits (421), Expect = 1.121e-47
Identity = 98/291 (33.68%), Postives = 152/291 (52.23%), Query Frame = 2

Query:  254 ESWWHYKLKEVG----GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQF-NVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCR 1096
            E WW YK    G    GP  WG   +       W+ C++G+ QSPV +   +++YD  L PL +     E L     NTG+ + F    +  V + GGPL Y + +  + L FG +   GS+H IN+  +  E+Q+  +N+ LY N+S A     G+A L  F  + + SN   + L+       + YK++   ++ + +++L P +  FITY+GS+  PPC E+V WI+++  +++T  QM +LR L  S+N  S I   ++ N RP Q L  RALR N      ER CR
Sbjct:   32 EDWWSYKDNLQGNFVPGPPFWGLVNAA------WSLCAVGKRQSPVDVELKRVLYDPFLPPLRL-STGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLL--SQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCR 313

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BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Match: cah-1 (Putative carbonic anhydrase-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20781])

HSP 1 Score: 165.622 bits (418), Expect = 7.330e-48
Identity = 100/297 (33.67%), Postives = 147/297 (49.49%), Query Frame = 2

Query:  197 YVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNV----EKGSVTIKGGPL-SYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI-IADNFRPPQNLNRRALRTNIQ 1069
            +  F I+     S L       W Y     GGP  WG         K W  C  GR+QSP+ I  D+L++D  + P+ +       +  + +NTG+ ++  +    +K SV I  GPL  Y Y V RI    G+K+  GS+H IN   +P E+Q+  YN  LY N++ A    +GIA L        ++N +   L  A+ ++ YKD    +   +   LLP T++ ITYEGS+  P C+E+V WIILN+PI + +   +    L  S      + +A NFR  Q  N R +RTNIQ
Sbjct:    8 FPLFLIILTCHISPLKSSQNYQWSYDSDVFGGPHFWGLVE------KDWWMCKKGRLQSPIDIQPDRLLFDASVKPVRL---DKLPVVSEFVNTGQMVRVRIGYSSKKPSVNITSGPLYGYRYRVQRIDFHMGRKNENGSEHTINGRRFPMEVQLVAYNTDLYPNFTSASKSPHGIAILSVLVDFGPETNQELIKLTIATASISYKDQRVQLADFEPWRLLPFTRDIITYEGSLTSPGCHETVTWIILNQPIFIKKEHFEEWSHLYLSMEGAEKVPVAPNFRKIQETNNRLVRTNIQ 295

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BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Match: cah-2 (Putative carbonic anhydrase-like protein 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18932])

HSP 1 Score: 155.221 bits (391), Expect = 1.406e-43
Identity = 87/272 (31.99%), Postives = 145/272 (53.31%), Query Frame = 2

Query:  284 VGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEI----FEDSNENLELQALNTGKDIQFNVEKGSVTIKGGP-LSYEYEVYRILLKFGK--KSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRA--SKNDWSGIIADNFRPPQNLNRRALRTNIQL 1072
            V GP+ WG           W  C+ G+MQSPV+I   QL+YD  L P+ I     E   EN     + T KD+     + ++ I GGP + Y Y++++I + FG+  +  +GS+H ++   +P EIQ+  YN  LY N+S A++   G+ ++     I   ++ +   L  AS+++ YK     +   +   LLP T  ++TYEGS+  P C+E+V W+ILN PI +T   ++   +++   +K      +   +RP ++LN R +RTNI +
Sbjct:   14 VIGPDFWGL------LHGDWRMCTAGQMQSPVNIDPSQLLYDPHLMPINIEGNIVEAVFENTGQLPVVTVKDLP---NRPTINITGGPTMPYRYKLHQISVHFGRADEGEKGSEHTVDRVRFPAEIQLLAYNSALYPNFSVAMTSPRGLLAVSVIVDIGKTTSVELRRLTVASQSINYKGQTTNLTDFQPSALLPKTSHYVTYEGSLTFPGCHETVTWVILNNPIYITNDDLQIWNEMQKTETKQPEPSYMTPAYRPLKSLNGRLVRTNINV 276

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BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Match: cah-1 (Putative carbonic anhydrase-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q20781])

HSP 1 Score: 130.568 bits (327), Expect = 9.327e-36
Identity = 74/196 (37.76%), Postives = 106/196 (54.08%), Query Frame = 2

Query:  488 IQFNVEKGSVTIKGGPL-SYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI-IADNFRPPQNLNRRALRTNIQ 1069
            I ++ +K SV I  GPL  Y Y V RI    G+K+  GS+H IN   +P E+Q+  YN  LY N++ A    +GIA L        ++N +   L  A+ ++ YKD    +   +   LLP T++ ITYEGS+  P C+E+V WIILN+PI + +   +    L  S      + +A NFR  Q  N R +RTNIQ
Sbjct:    6 IGYSSKKPSVNITSGPLYGYRYRVQRIDFHMGRKNENGSEHTINGRRFPMEVQLVAYNTDLYPNFTSASKSPHGIAILSVLVDFGPETNQELIKLTIATASISYKDQRVQLADFEPWRLLPFTRDIITYEGSLTSPGCHETVTWIILNQPIFIKKEHFEEWSHLYLSMEGAEKVPVAPNFRKIQETNNRLVRTNIQ 201

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BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Match: cah-5 (Putative carbonic anhydrase 5 [Source:UniProtKB/Swiss-Prot;Acc:Q10462])

HSP 1 Score: 87.8113 bits (216), Expect = 3.264e-19
Identity = 69/267 (25.84%), Postives = 126/267 (47.19%), Query Frame = 2

Query:  290 GPEH-WG-QSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNV----EKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFF-KIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLP-STKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRAS---KNDWSGIIADNFRPPQNLNRRALR 1057
            G +H WG    + P+ W+    C     QSP+ I    + Y   L     F + + + +++  NTG+ +        +     I+GG L + Y++ +  L +G+  + GS+H + +  YP E+ +      L     +A+S+  G+A +  F  K +      F+ +     ++ +  N   +K  +   +LP  T+ F  YEGS+  P C E+V+W +L EP++++  Q+  LR+L      K+D       N+RP Q LN R ++
Sbjct:   23 GSDHGWGYDENNGPDTWQ--GKCQNHLKQSPIDIRAPDVDY--ALLHRMHFLNYDMDGKIELSNTGRTLFAGGFESWQHKQPMIQGGGLKHRYKLAQFHLHWGQNDAVGSEHAMGSLHYPAELHLVHVREGL--TLKEALSRPDGLAVVGVFLAKTNDPVANKFSPISERLHDLRHSGNKTELKNFRTKYVLPLDTEAFYRYEGSLTTPDCSEAVIWTVLAEPMAISSHQLHLLRQLHNKELVKSD------KNYRPLQPLNGRRIQ 277

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BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Match: cah-3 (Putative carbonic anhydrase 3 [Source:UniProtKB/Swiss-Prot;Acc:Q27504])

HSP 1 Score: 83.5741 bits (205), Expect = 3.161e-18
Identity = 62/256 (24.22%), Postives = 113/256 (44.14%), Query Frame = 2

Query:  338 HWAWCS----------LGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS--VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYK----DNIDTVKGIKIDMLLPSTKE-FITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRAL 1054
            HW++C            G+ QSP++I   ++        ++ F + +  ++   +N G  +Q   E  S    I GG L   Y + +    +G+  + GS+H +    YP E+ +              +     +A +  F ++  +        ++  E V+ K    + +  V+ +++   LP+ K  F  YEGS+  PPC E V W I  EP++VT  Q++  R+++  +      I  N+RP QNLN R +
Sbjct:    4 HWSYCDDDECGPNRWPTGQHQSPINIDLGEVERKDTHDGIK-FVNYDHPIQGDIVNNGHSVQMTPELRSEHPEIYGGGLDQVYRLVQYHFHWGENDNEGSEHTLGGLRYPAELHLV----------HQGVEDPGKLAVVGVFLQLGKE-----GKALSNEERVLGKLCNPETVTRVENVRLSEKLPANKRSFWRYEGSLTTPPCSEIVTWTIFTEPVTVTHDQLELFRQVQDIEKR---PIKKNYRPTQNLNDRKI 240

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BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Match: CARPA (gene:FBgn0029962 transcript:FBtr0343348)

HSP 1 Score: 204.527 bits (519), Expect = 2.543e-62
Identity = 111/325 (34.15%), Postives = 176/325 (54.15%), Query Frame = 2

Query:  173 SIDSSMIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS---VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTER--VC-RIERDFFYSVN 1126
            S   S   ++  S + +  +S++   WE WW Y    + GP  WG           W  C+ GR QSP+ +  D+L++D  L PL I       +     NTG+ + F V+K +   V I GGPL+Y Y+   I + +G ++ RGS+H I  +++PGEIQIYG+N+ LY N S+A  K+ GI  L    +I    N +   + +    V+Y+     ++ I +  LLP+T  +ITYEGS  HP C+ES +WII+N+PI +T+ ++  LR+L + S++     + +N RP Q+L+ R +RTNI     +    C  + +D +Y  N
Sbjct:    9 SFCCSTAGFIACSAIVLLCSSEVLSSWEEWWTYD--GISGPSFWGLINPQ------WNMCNKGRRQSPIDVVPDKLLFDPYLRPLHI---DKHKVSGTLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQGYSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQIGETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLPNTDHYITYEGSTTHPGCWESTVWIIVNKPIYITKQELYQLRRLMQGSESTPKAPLGNNARPVQSLHHRTVRTNIDFKRNKNQYACPSMYKDMYYRAN 322

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BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Match: CARPA (gene:FBgn0029962 transcript:FBtr0300019)

HSP 1 Score: 204.527 bits (519), Expect = 2.543e-62
Identity = 111/325 (34.15%), Postives = 176/325 (54.15%), Query Frame = 2

Query:  173 SIDSSMIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS---VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTER--VC-RIERDFFYSVN 1126
            S   S   ++  S + +  +S++   WE WW Y    + GP  WG           W  C+ GR QSP+ +  D+L++D  L PL I       +     NTG+ + F V+K +   V I GGPL+Y Y+   I + +G ++ RGS+H I  +++PGEIQIYG+N+ LY N S+A  K+ GI  L    +I    N +   + +    V+Y+     ++ I +  LLP+T  +ITYEGS  HP C+ES +WII+N+PI +T+ ++  LR+L + S++     + +N RP Q+L+ R +RTNI     +    C  + +D +Y  N
Sbjct:    9 SFCCSTAGFIACSAIVLLCSSEVLSSWEEWWTYD--GISGPSFWGLINPQ------WNMCNKGRRQSPIDVVPDKLLFDPYLRPLHI---DKHKVSGTLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQGYSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQIGETPNPELRIITSTFNKVLYRGFSTPIRHISVRSLLPNTDHYITYEGSTTHPGCWESTVWIIVNKPIYITKQELYQLRRLMQGSESTPKAPLGNNARPVQSLHHRTVRTNIDFKRNKNQYACPSMYKDMYYRAN 322

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BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Match: CARPB (gene:FBgn0052698 transcript:FBtr0346170)

HSP 1 Score: 193.741 bits (491), Expect = 2.576e-58
Identity = 104/293 (35.49%), Postives = 156/293 (53.24%), Query Frame = 2

Query:  239 LSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVT----------IKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTE 1084
            L+  WE WW Y    + GP  WG     PE    W+ C+ GR QSPV++   +L++D  L P+ I +     L     NTG  + F     +V           I GGPLSY Y  + I + +G     GS+H +  +T+P EIQI+GYN  LY+N+SDA+++  GI  +    ++   SN +   L    E + Y  +   VK + I  LLP T  ++TY+GS   P C+E+V W++LN+PI +T+ Q+  LR+L + S +     + +N+RPPQ L  R +RTNI    T+
Sbjct:   22 LAVSWEDWWTYD--GISGPAFWGLIN--PE----WSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGL---ITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGLLPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPLLHRPIRTNIDFKTTK 303

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BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Match: CARPB (gene:FBgn0052698 transcript:FBtr0336923)

HSP 1 Score: 193.741 bits (491), Expect = 2.576e-58
Identity = 104/293 (35.49%), Postives = 156/293 (53.24%), Query Frame = 2

Query:  239 LSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVT----------IKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTE 1084
            L+  WE WW Y    + GP  WG     PE    W+ C+ GR QSPV++   +L++D  L P+ I +     L     NTG  + F     +V           I GGPLSY Y  + I + +G     GS+H +  +T+P EIQI+GYN  LY+N+SDA+++  GI  +    ++   SN +   L    E + Y  +   VK + I  LLP T  ++TY+GS   P C+E+V W++LN+PI +T+ Q+  LR+L + S +     + +N+RPPQ L  R +RTNI    T+
Sbjct:   22 LAVSWEDWWTYD--GISGPAFWGLIN--PE----WSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGL---ITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGLLPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPLLHRPIRTNIDFKTTK 303

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BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Match: CARPB (gene:FBgn0052698 transcript:FBtr0307489)

HSP 1 Score: 193.741 bits (491), Expect = 2.576e-58
Identity = 104/293 (35.49%), Postives = 156/293 (53.24%), Query Frame = 2

Query:  239 LSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVT----------IKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTE 1084
            L+  WE WW Y    + GP  WG     PE    W+ C+ GR QSPV++   +L++D  L P+ I +     L     NTG  + F     +V           I GGPLSY Y  + I + +G     GS+H +  +T+P EIQI+GYN  LY+N+SDA+++  GI  +    ++   SN +   L    E + Y  +   VK + I  LLP T  ++TY+GS   P C+E+V W++LN+PI +T+ Q+  LR+L + S +     + +N+RPPQ L  R +RTNI    T+
Sbjct:   22 LAVSWEDWWTYD--GISGPAFWGLIN--PE----WSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGL---ITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGLLPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPLLHRPIRTNIDFKTTK 303

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BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
Match: ca10b (carbonic anhydrase Xb [Source:ZFIN;Acc:ZDB-GENE-080815-2])

HSP 1 Score: 194.897 bits (494), Expect = 1.087e-58
Identity = 111/294 (37.76%), Postives = 161/294 (54.76%), Query Frame = 2

Query:  242 SKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALI--AASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVC 1093
            SK  + WW YK    G     P  WG   +       W  C++G+ QSPV+I T ++I+D  L PL +       +     NTG+ +    +K   V I GGPLSY Y +  I L FG + +RGS+H++N   +PGE+Q+  YN+ LY NYSDA+    GIA +  F KI   +N     ++       + YK +   + G+ I+ L P T  FITYEGSI  PPC E+  WI++N+PI +++ +M++LR L  S+N  S I   + DN RP Q L++R +RTNI  +   R C
Sbjct:   25 SKLHDGWWAYKDVVQGSFIPVPSFWGLVNTA------WNLCAIGKRQSPVNIETSRMIFDPFLNPLRL-NAGQRKVSGTMYNTGRHVSLRPDKSHLVNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQAFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAYLLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLL--SQNQPSQIFLSMGDNMRPTQTLHQRCIRTNINFS-QRRDC 308

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BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
Match: ca10a (carbonic anhydrase Xa [Source:ZFIN;Acc:ZDB-GENE-051030-123])

HSP 1 Score: 192.586 bits (488), Expect = 1.172e-57
Identity = 113/318 (35.53%), Postives = 168/318 (52.83%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV  +      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL +       +     NTG+ +   ++K   V I GGP++Y + +  I L FG +  +GS+H++N   + GE+Q+  YN  LY+NY++A     G+  +  F KI   SN+    ++       + YK++   + G+ I+ + P T  FITYEGS+  PPCYE+  WI++N+PI VT+ QM ++R L  S+N  S I   ++DN RP Q LN R +RTNI  ++  + C   R     Y VN+
Sbjct:   16 IVCTSAQPNPPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRL-NTGGRKVGGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDGQGSEHLLNGQAFSGEVQLIHYNHELYTNYTEAAKSPNGLVIVSIFMKISETSNSFLNRMLNRDTITRITYKNDAYLLSGLNIEEVYPETASFITYEGSMTIPPCYETATWILMNKPIYVTKMQMHSMRLL--SQNQPSQIFLSMSDNVRPVQPLNNRCIRTNINFSMQGKDCPNNRAQKLQYRVNE 324

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Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV  +      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL +       +     NTG+ +   ++K   V I GGP++Y + +  I L FG +  +GS+H++N   + GE+Q+  YN  LY+NY++A     G+  +  F KI   SN+    ++       + YK++   + G+ I+ + P T  FITYEGS+  PPCYE+  WI++N+PI VT+ QM ++R L  S+N  S I   ++DN RP Q LN R +RTNI  ++  + C   R     Y VN+
Sbjct:   16 IVCTSAQPNPPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRL-NTGGRKVGGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDGQGSEHLLNGQAFSGEVQLIHYNHELYTNYTEAAKSPNGLVIVSIFMKISETSNSFLNRMLNRDTITRITYKNDAYLLSGLNIEEVYPETASFITYEGSMTIPPCYETATWILMNKPIYVTKMQMHSMRLL--SQNQPSQIFLSMSDNVRPVQPLNNRCIRTNINFSMQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
Match: ca10a (carbonic anhydrase Xa [Source:ZFIN;Acc:ZDB-GENE-051030-123])

HSP 1 Score: 157.532 bits (397), Expect = 2.346e-45
Identity = 84/227 (37.00%), Postives = 131/227 (57.71%), Query Frame = 2

Query:  473 NTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            NTG+ +   ++K   V I GGP++Y + +  I L FG +  +GS+H++N   + GE+Q+  YN  LY+NY++A     G+  +  F KI   SN+    ++       + YK++   + G+ I+ + P T  FITYEGS+  PPCYE+  WI++N+PI VT+ QM ++R L  S+N  S I   ++DN RP Q LN R +RTNI  ++  + C   R     Y VN+
Sbjct:    7 NTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDGQGSEHLLNGQAFSGEVQLIHYNHELYTNYTEAAKSPNGLVIVSIFMKISETSNSFLNRMLNRDTITRITYKNDAYLLSGLNIEEVYPETASFITYEGSMTIPPCYETATWILMNKPIYVTKMQMHSMRLL--SQNQPSQIFLSMSDNVRPVQPLNNRCIRTNINFSMQGKDCPNNRAQKLQYRVNE 231

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BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
Match: ca2 (carbonic anhydrase II [Source:ZFIN;Acc:ZDB-GENE-031219-5])

HSP 1 Score: 136.732 bits (343), Expect = 3.004e-37
Identity = 79/269 (29.37%), Postives = 136/269 (50.56%), Query Frame = 2

Query:  266 HYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKN-DWSGIIADNFRPPQNLNRRALRTNIQ 1069
            H+   +  GP+ WG+S  +            G  QSP+ I +    YD++LTPL++  D + +L++Q       + F  ++ S T+ GGP++  + + +    +G    +GS+H +N   YP E+ +  +N   Y ++ DA+ K  G+A +  F KI    N     ++ A + +  K            +LLPS+ ++ TY GS+  PP  ESV WI+  + ISV+  QMK  R L  S + + +  + +N+RPPQ L  R +R + +
Sbjct:    4 HWGYDKHNGPDKWGESYPIAN----------GSRQSPIDIKSSTTTYDEKLTPLKLKYDPSTSLDIQNNGHSFQVSFVDDQNSSTLTGGPVTGTFRLKQFHFHWGSADDKGSEHTVNGKCYPAELHLVHWN-TKYPSFKDAVDKPDGLAVVGVFLKIGA-DNPKLQKILDAMDAIKSKGKQTPFPNFDPSVLLPSSLDYWTYLGSLTTPPLLESVTWIVCKQSISVSSAQMKRFRSLLFSGDGEKACCMVNNYRPPQPLKGRVVRASFK 260

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BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Match: CA10 (carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC:1369])

HSP 1 Score: 194.126 bits (492), Expect = 5.239e-58
Identity = 110/297 (37.04%), Postives = 160/297 (53.87%), Query Frame = 2

Query:  245 KKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER 1105
            K  E WW YK    G     P  WG   S       W  C++G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGPL+Y + +  I L FG +  +GS+H++N   + GE+Q+  YN  LY+N +DA     G+  +  F K+   SN     ++       + YK++   ++G+ I+ + P T  FITY+GS+  PPCYE+  WII+N+PI +T  QM +LR L  S+N  S I   ++DNFRP Q+LN R +RTNI   L  + C   R
Sbjct:   36 KIHEGWWTYKEVVQGSFVPVPSFWGLVNSA------WNLCAVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPLTYSHRLEEIRLHFGSEDGQGSEHLLNGQAFSGEVQLIHYNHELYTNVTDAAKSPNGLVVISIFIKVTDSSNLFLNRMLNRDTITRITYKNDAYLLQGLNIEEIYPETSSFITYDGSMTIPPCYETASWIIMNKPIYITRMQMHSLRLL--SQNQPSQIFSSMSDNFRPVQSLNNRCIRTNINFRLQGKDCPNNR 323

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BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Match: CA11 (carbonic anhydrase XI [Source:NCBI gene;Acc:100493884])

HSP 1 Score: 185.267 bits (469), Expect = 1.041e-54
Identity = 106/313 (33.87%), Postives = 171/313 (54.63%), Query Frame = 2

Query:  194 IYVFFSIVSVTWASQLS--KKWESWWHYKLKEVG----GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCR 1096
            + +  +  ++  A+Q S  K +E WW YK    G    GP  WG   S       W  C++G+ QSP++I T Q+I+D  L PL +   +   +     NTG+ + F ++K   V I GGPL Y + +  ++L FG ++S GS+H++N  T  GE+Q+  YN+ LYSN ++A     G+A +  F  +   SN+    ++       + +++    ++ + I+ L P T  F+TY+GS+  PPCYE+V WI+++ P+++T  QM +LR L  S+N  S I   ++DNFRP Q L  R LR N+      R C+
Sbjct:    9 VLILQASAAIYTAAQFSPAKTYEEWWAYKEAVQGSFVPGPAFWGLVNSA------WNLCTIGKRQSPININTSQIIFDPFLPPLRL-SMTGTTVSGTMHNTGRHVSFRLDKEQPVNISGGPLLYNHRLEEVMLHFGSENSIGSEHLMNKETSAGEVQLIHYNQDLYSNVTEASRNPNGLAVISLFLNVADNSNSFLNRMLNRETITRISFRNEATYIQDLSIEDLYPDTFGFLTYQGSMTIPPCYETVTWIVIDRPLNITSMQMHSLRLL--SQNQPSQIFQSMSDNFRPVQPLFHRGLRGNLDFRKPGRKCK 312

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Match: CA11 (carbonic anhydrase XI [Source:NCBI gene;Acc:100493884])

HSP 1 Score: 184.111 bits (466), Expect = 4.520e-54
Identity = 103/295 (34.92%), Postives = 163/295 (55.25%), Query Frame = 2

Query:  242 SKKWESWWHYKLKEVG----GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEK-GSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCR 1096
            +K +E WW YK    G    GP  WG   S       W  C++G+ QSP++I T Q+I+D  L PL +   +   +     NTG+ + F ++K   V I GGPL Y + +  ++L FG ++S GS+H++N  T  GE+Q+  YN+ LYSN ++A     G+A +  F  +   SN+    ++       + +++    ++ + I+ L P T  F+TY+GS+  PPCYE+V WI+++ P+++T  QM +LR L  S+N  S I   ++DNFRP Q L  R LR N+      R C+
Sbjct:   40 AKTYEEWWAYKEAVQGSFVPGPAFWGLVNSA------WNLCTIGKRQSPININTSQIIFDPFLPPLRL-SMTGTTVSGTMHNTGRHVSFRLDKEQPVNISGGPLLYNHRLEEVMLHFGSENSIGSEHLMNKETSAGEVQLIHYNQDLYSNVTEASRNPNGLAVISLFLNVADNSNSFLNRMLNRETITRISFRNEATYIQDLSIEDLYPDTFGFLTYQGSMTIPPCYETVTWIVIDRPLNITSMQMHSLRLL--SQNQPSQIFQSMSDNFRPVQPLFHRGLRGNLDFRKPGRKCK 325

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Match: ca8 (carbonic anhydrase VIII [Source:NCBI gene;Acc:496646])

HSP 1 Score: 140.584 bits (353), Expect = 3.286e-38
Identity = 78/247 (31.58%), Postives = 133/247 (53.85%), Query Frame = 2

Query:  359 GRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPL--SYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPST--KEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRAS------KNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            G  QSP++I + + +YD  L  + +        + + +N G  +Q  ++  SV +KGGPL   +EYE+  +   +GK++ RGS+H +N   +P E+ +  +N  LY +  +A+ K +GI  +  F +I  K N    A+    +++ YK    T+     + LLP    +++  YEGS+  PPC E V WI+   P++V++TQ++  R+LR         +   G++ADNFRP Q L+ R +R   Q
Sbjct:   38 GDYQSPININSREAMYDPSLLEVRLTPSYVVCRDCEVINDGHVVQILLKSKSV-LKGGPLPRGHEYELNEVRFHWGKENQRGSEHTVNFKAFPMELHLIHWNSTLYRSLEEAMGKVHGIVIISLFVQIG-KENIGLKAITEVLQDIFYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTMPPCSEGVTWILFRYPLTVSQTQIEEFRRLRTHIKGADLPDGCDGLMADNFRPTQPLSDRIIRAAFQ 282

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Match: proca1 (protein interacting with cyclin A1 [Source:Xenbase;Acc:XB-GENE-1005546])

HSP 1 Score: 126.716 bits (317), Expect = 2.756e-33
Identity = 73/253 (28.85%), Postives = 123/253 (48.62%), Query Frame = 2

Query:  323 PEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRK---LRASKNDWSGIIADNFRPPQNLNRRALRTNIQL 1072
            P  W H+   + G  QSP+ I ++Q +++  L PL I  D   ++ L        ++F+       I GGPL   Y + +    +G + + GS+H ++  +YP E+ +  +N   YS++ +A +   G+  +  F +   + ++    L  A   V +K             LLPS+ E+ TY GS+  PP  ESV WI+L EPI V+E QM+  RK       + +    + +NFRPPQ L  R ++ + + 
Sbjct:   15 PSEWHHYFPIAEGNRQSPIDIVSNQAVFNPSLNPLVISYDHCTSINLSNNGHSVMVEFDDYDDKTVITGGPLEGSYRLKQFHFHWGTQRNSGSEHTVDGKSYPCELHLVHWNARAYSSFGEAAAAPDGLVVIGVFLETGGQ-HSGLNRLTDALYMVKFKGTKTQFDDFNPKCLLPSSFEYWTYPGSLTTPPLNESVTWIVLKEPIKVSEKQMERFRKTLLFSGEEEEQRIHMVNNFRPPQPLKGRKVQASFKC 266

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BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
Match: Car10 (carbonic anhydrase 10 [Source:MGI Symbol;Acc:MGI:1919855])

HSP 1 Score: 196.438 bits (498), Expect = 3.376e-59
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
Match: Car10 (carbonic anhydrase 10 [Source:MGI Symbol;Acc:MGI:1919855])

HSP 1 Score: 179.489 bits (454), Expect = 6.528e-53
Identity = 111/318 (34.91%), Postives = 163/318 (51.26%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTG-KDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I             NTG + ++            GP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-------------NTGGRKVR------------GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 300

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BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
Match: Car11 (carbonic anhydrase 11 [Source:MGI Symbol;Acc:MGI:1336193])

HSP 1 Score: 164.466 bits (415), Expect = 5.397e-47
Identity = 100/321 (31.15%), Postives = 161/321 (50.16%), Query Frame = 2

Query:  164 AKISIDSSMIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVG----GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQF-NVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCR 1096
            A++S   +++++      +    +      E WW YK    G    GP  WG   +       W+ C++G+ QSPV +   +++YD  L PL +     E L     NTG+ + F    +  V + GGPL Y + +  + L FG +   GS+H IN+  +  E+Q+  +N+ LY N S A     G+A L  F  +   SN   + L+       + YK++   ++ + +++L P +  FITY+GS+  PPC E+V WI+++  +++T  QM +LR L  S+N  S I   ++ N RP Q L  RALR N      ER CR
Sbjct:    5 ARLSAPQALVLWAALGAAAHIGPA---PDPEDWWSYKENLQGNFVPGPPFWGLVNAA------WSLCAVGKRQSPVDVELKRVLYDPFLPPLRL-STGGEKLRGTLYNTGRHVSFLPASRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHEGFSAEVQLIHFNQELYGNLSAASRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLL--SQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCR 313

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BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
Match: Car7 (carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:103100])

HSP 1 Score: 139.428 bits (350), Expect = 3.850e-38
Identity = 82/259 (31.66%), Postives = 129/259 (49.81%), Query Frame = 2

Query:  302 WGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQ--FNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI-IADNFRPPQNLNRRALRTNIQ 1069
            +GQ    P  W      + G  QSP++I + Q +Y   L PLE+F ++   + L   N G  +Q  FN       + GGPL   Y + ++   +GKK   GS+H ++  ++P E+ +  +N   YS + +A +   G+A +  F +   + +     L  A   V +KD            LLP+++ + TY GS+  PP  ESV WI+L EPI ++E QM+  R L  +  D   I + DNFRPPQ L  R ++ + Q
Sbjct:    9 YGQDDG-PSNWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELFYEAC--MSLSITNNGHSVQVDFNDSDDRTVVSGGPLEGPYRLKQLHFHWGKKRDMGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAAAAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFKDTKAQFSCFNPKCLLPTSRHYWTYPGSLTTPPLSESVTWIVLREPIRISERQMEKFRSLLFTSEDDERIHMVDNFRPPQPLKGRVVKASFQ 263

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BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Match: sp|A0JN41|CAH10_BOVIN (Carbonic anhydrase-related protein 10 OS=Bos taurus OX=9913 GN=CA10 PE=2 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.430e-58
Identity = 115/318 (36.16%), Postives = 170/318 (53.46%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q+LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETANWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQSLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Match: sp|Q5R4U0|CAH10_PONAB (Carbonic anhydrase-related protein 10 OS=Pongo abelii OX=9601 GN=CA10 PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.361e-58
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Match: sp|P61215|CAH10_MOUSE (Carbonic anhydrase-related protein 10 OS=Mus musculus OX=10090 GN=Ca10 PE=1 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.361e-58
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Match: sp|Q9N085|CAH10_MACFA (Carbonic anhydrase-related protein 10 OS=Macaca fascicularis OX=9541 GN=CA10 PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.361e-58
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Match: sp|Q9NS85|CAH10_HUMAN (Carbonic anhydrase-related protein 10 OS=Homo sapiens OX=9606 GN=CA10 PE=2 SV=1)

HSP 1 Score: 196.438 bits (498), Expect = 2.361e-58
Identity = 115/318 (36.16%), Postives = 169/318 (53.14%), Query Frame = 2

Query:  212 IVSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE--NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            IV ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV+I T  +I+D  LTPL I       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+N ++A     G+  +  F K+   SN     ++       + YK++   ++G+ I+ L P T  FITY+GS+  PPCYE+  WII+N+P+ +T  QM +LR L  S+N  S I   ++DNFRP Q LN R +RTNI  +L  + C   R     Y VN+
Sbjct:   16 IVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVNIETSHMIFDPFLTPLRI-NTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLL--SQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. TrEMBL
Match: A0A4E0RAH6 (Carbonic anhydrase XIII OS=Fasciola hepatica OX=6192 GN=D915_006413 PE=3 SV=1)

HSP 1 Score: 283.878 bits (725), Expect = 1.226e-89
Identity = 129/296 (43.58%), Postives = 192/296 (64.86%), Query Frame = 2

Query:  251 WESWWHYKLKEVG--GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVNDP 1132
            W+  W YK +E+G  GPE WG   +   Y   W  C +GR QSPV I TD+L+YD  L P+EI    +  LEL   N G+D++ ++    + + GGP SYE++V  + +KFG  S+RGSDH ++    PGE+QIY +NR+LY N+SDA+S+ +GI ++  FFK+   SN D   ++AA+E  I+K     ++G+++  L+ ST E++TY+GS+P P C+E+V WIILN PISV+ET++KTLR+LR +   WSG +ADN RP Q +N R + TNI     + +C +++   Y+ N P
Sbjct:   47 WDFPWSYKSEEIGVIGPEMWGTRHTGSGYATQWPLCQIGRHQSPVDIQTDRLVYDHSLKPIEI-SGGDLQLELIVTNVGQDLRLSLLSDQIILSGGPFSYEFQVVSMHIKFGSVSTRGSDHRVDGRNLPGELQIYAFNRILYKNFSDALSQPHGIVAVSVFFKLCNISNKDILGIVAAAEKTIFKGQTFQLRGLELRSLISSTTEYMTYDGSLPFPGCHETVKWIILNHPISVSETELKTLRRLRVANTLWSGSMADNVRPVQAINHRTISTNINFNAVDDICNVKKQVSYTANLP 341

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BLAST of Carbonic anhydrase-related vs. TrEMBL
Match: G4VIP7 (Carbonic anhydrase-related OS=Schistosoma mansoni OX=6183 GN=Smp_159710 PE=3 SV=1)

HSP 1 Score: 277.33 bits (708), Expect = 4.785e-87
Identity = 130/312 (41.67%), Postives = 197/312 (63.14%), Query Frame = 2

Query:  194 IYVFFSIVSVTWASQLSK---------KWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNV--EKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCR 1096
            +   F+I+S T   +++           W++WWHYK   +GGP HWGQ+  M      W  C  G+MQSP+SI+T  L+YD  L PL+I   S++ ++++ +NTG+D+Q  +     SV    GPL Y Y+ +  L+KFG +S RGSDH I+   +P E+Q+Y +N +LY N+S+A+SK  G+A L   FKI  +S+ D  AL++ +E V  K     + G+ +D +LPST ++ITY+GS+P P CYE+  WI+LN+PI +TETQ+K+LR+LR +    SG +ADN+R  Q LN R++RTNI    + R+ +
Sbjct:    5 VLTVFAIISFTKTRRMNALWHDGSWDPSWDTWWHYKEGVMGGPSHWGQTAFMAIASDVWPACYQGKMQSPISISTKHLLYDPNLVPLKI-SGSDKQIDVEVVNTGQDLQVKILDSTASVVFSEGPLVYNYKFFGALIKFGSRSDRGSDHRIDGIAFPAELQLYAFNFILYQNFSNALSKPNGLAVLSVLFKIGDQSSADLEALLSTAEQVQLKGQSKRLHGLLLDAVLPSTMQYITYQGSLPFPACYETATWILLNQPIVITETQLKSLRQLRIAPFRGSGSMADNYRTIQKLNNRSVRTNIDFKKSLRIVK 315

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BLAST of Carbonic anhydrase-related vs. TrEMBL
Match: A0A3R7ESL3 (Carbonic anhydrase-related protein 10 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CA10 PE=4 SV=1)

HSP 1 Score: 272.707 bits (696), Expect = 1.144e-85
Identity = 127/309 (41.10%), Postives = 195/309 (63.11%), Query Frame = 2

Query:  200 VFFSIVSVTW-ASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS--VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFY 1117
            VF + +  +W  +  +  W++WWHYK   +GGP HWGQ+  M      W  C  G++QSP+SI++  L YD  L PL I    ++ ++L+  N G+D++ ++   S  + + GGPLSYEY V+  L+KFG KS  GSDH ++   +P E+Q+Y YN +LY+N S A+ + +G+A++  F K+    + D +AL+A +E V  +     + G+ I  LLPSTK+++TYEGSIP P C+E+V W++LN+ + +TETQ+K LR+LR +    SG ++DNFRP Q+LN R++RTNIQ T     C +     Y
Sbjct:    1 VFCNSLGTSWHETSWNAAWDTWWHYKEGVIGGPSHWGQTAYMTYADDVWPACHKGKLQSPISISSSNLTYDPSLQPLVIV-GKDKQIDLEISNAGQDLRIDLLDASPQILLTGGPLSYEYRVFGALIKFGSKSQHGSDHQVDGVPFPAEMQLYAYNYLLYANVSMAVPRPHGLAAIAVFLKVGEHPSADLSALLATAEEVQLRGQSRRLNGLLISALLPSTKQYMTYEGSIPFPACHETVTWVVLNQAMIITETQLKALRELRIAPFANSGRMSDNFRPTQSLNNRSVRTNIQFTEQSEYCSMRPRVSY 308

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BLAST of Carbonic anhydrase-related vs. TrEMBL
Match: A0A504YCI5 (Carbonic anhydrase XIII OS=Fasciola gigantica OX=46835 GN=FGIG_03328 PE=3 SV=1)

HSP 1 Score: 271.166 bits (692), Expect = 3.764e-85
Identity = 125/276 (45.29%), Postives = 182/276 (65.94%), Query Frame = 2

Query:  251 WESWWHYKLKEVG--GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQL 1072
            W+  W YK +E+G  GPE WG   +   Y   W  C +GR QSPV I TD+L+YD  L P+EI    +  LEL   N G+D++ ++    + + GGP SYE++V  + +KFG  S+RGSDH ++    PGE+QIY +NR+LY N+SDA+S+ +GI ++  FFK+   SN D   ++AA+E  I+K     ++G+++  L+ ST E++TY+GS+P P C+E+V WIILN PISV+ET++KTLR+LR +   WSG +ADN RP Q +N R + TNI  
Sbjct:   30 WDFPWSYKSEEIGVIGPEMWGTRHTGSGYATQWPLCQIGRHQSPVDIQTDRLVYDHSLKPIEI-SGGDLQLELIVTNVGQDLRLSLLSDQIILSGGPFSYEFQVVSMHIKFGSVSTRGSDHRVDGRNLPGELQIYAFNRILYKNFSDALSQPHGIVAVSVFFKLCNISNKDILGIVAAAEKTIFKGQTFQLRGLELRSLISSTTEYMTYDGSLPFPGCHETVKWIILNHPISVSETELKTLRRLRVANTLWSGSMADNVRPVQAINHRTISTNINF 304

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BLAST of Carbonic anhydrase-related vs. TrEMBL
Match: G7YJ22 (Carbonic anhydrase-related protein 10 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_109216 PE=4 SV=1)

HSP 1 Score: 271.937 bits (694), Expect = 7.807e-85
Identity = 126/303 (41.58%), Postives = 195/303 (64.36%), Query Frame = 2

Query:  200 VFFSIVSVTW-ASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS--VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRI 1099
            VF + +  +W  +  +  W++WWHYK   +GGP HWGQ+  M      W  C  G++QSP+SI++  L YD  L PL I    ++ ++L+  N G+D++ ++   S  + + GGPLSYEY V+  L+KFG KS  GSDH ++   +P E+Q+Y YN +LY+N S A+ + +G+A++  F K+    + D +AL+A +E V  +     + G+ I  LLPSTK+++TYEGSIP P C+E+V W++LN+ + +TETQ+K LR+LR +    SG ++DNFRP Q+LN R++RTNIQ T    +C +
Sbjct:   19 VFCNSLGTSWHETSWNAAWDTWWHYKEGVIGGPSHWGQTAYMTYADDVWPACHKGKLQSPISISSSNLTYDPSLQPLVIV-GKDKQIDLEISNAGQDLRIDLLDASPQILLTGGPLSYEYRVFGALIKFGSKSQHGSDHQVDGVPFPAEMQLYAYNYLLYANVSMAVPRPHGLAAIAVFLKVGEHPSADLSALLATAEEVQLRGQSRRLNGLLISALLPSTKQYMTYEGSIPFPACHETVTWVVLNQAMIITETQLKALRELRIAPFANSGRMSDNFRPTQSLNNRSVRTNIQFTEQAFLCCV 320

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BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Match: ca10b (carbonic anhydrase Xb [Source:ZFIN;Acc:ZDB-GENE-080815-2])

HSP 1 Score: 170.244 bits (430), Expect = 1.866e-49
Identity = 100/270 (37.04%), Postives = 150/270 (55.56%), Query Frame = 2

Query:  317 SMPEYW----KHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASE---NVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVC 1093
            ++P +W      W  CS+GR QSPV+  T +LI+D  LTP+ +     + +     NTG  +   +++   V + GGPLSY Y +  I L FG +  +GS+H++N   +PGE+Q+  YN+ LY NYS A     GIA +  F K  T     F   + + E    + YK +   ++G+ +  L P T  FITY+GS+  PPC ES  WI++N+PI +  +Q+++LR L  S+N    I   ++DN RP Q L++R LRTNI      R C
Sbjct:   32 AVPSFWGLVNTAWNLCSVGRRQSPVNSETRRLIFDPYLTPIRL-NTGGKKISGIMYNTGHHVSLRLDRAHLVNMSGGPLSYSYRLEEIRLHFGSEDGQGSEHLLNGQAFPGEVQLIHYNQDLYLNYSAAARSPNGIAVISIFMKEPTNL---FLIRMLSREIITRITYKKDAYVLEGLNLQDLFPETSRFITYDGSLTIPPCLESATWILMNKPIYI--SQIESLRLL--SQNQPMEIFLSMSDNNRPVQQLHQRCLRTNIHYNQQGRNC 293

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BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:103041882])

HSP 1 Score: 138.272 bits (347), Expect = 6.793e-38
Identity = 82/271 (30.26%), Postives = 133/271 (49.08%), Query Frame = 2

Query:  263 WHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL--RASKNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            W Y   E  GP  W +   + E          G  QSP++I  D+ +YD  L P+ +  D+  ++ +        ++F+       I+GGPL+  Y + +    +G K   GS+H ++  TY  E+ +  +N   Y ++ +A++ + G+A L  F +I  + +     +  A   V +K  +   +      LLP +  + TY GS+  PP YESV WI+L EPI V+E QM   R L     + +    + +NFRPPQ LN RA+R+N Q
Sbjct:    6 WGYG--EDDGPSAWSKDYPIAE----------GPRQSPINIVPDEAVYDANLPPISLNYDNCTSINISNNGHSVVVEFDDADDRSVIQGGPLNNAYRLKQFHFHWGGKGCHGSEHTVSGKTYTSELHLVHWNAARYGSFGEAVAASDGLAVLGVFLEIGDE-HRGLHKITDALYMVKFKGTVADFRDFNPKCLLPRSLGYWTYPGSLTTPPLYESVTWIVLAEPIEVSEKQMGKFRTLLFSGEEEEVRKRMENNFRPPQPLNGRAVRSNFQ 263

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:103041882])

HSP 1 Score: 138.272 bits (347), Expect = 9.855e-38
Identity = 79/262 (30.15%), Postives = 130/262 (49.62%), Query Frame = 2

Query:  290 GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL--RASKNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            GP  W +   + E          G  QSP++I  D+ +YD  L P+ +  D+  ++ +        ++F+       I+GGPL+  Y + +    +G K   GS+H ++  TY  E+ +  +N   Y ++ +A++ + G+A L  F +I  + +     +  A   V +K  +   +      LLP +  + TY GS+  PP YESV WI+L EPI V+E QM   R L     + +    + +NFRPPQ LN RA+R+N Q
Sbjct:   17 GPSAWSKDYPIAE----------GPRQSPINIVPDEAVYDANLPPISLNYDNCTSINISNNGHSVVVEFDDADDRSVIQGGPLNNAYRLKQFHFHWGGKGCHGSEHTVSGKTYTSELHLVHWNAARYGSFGEAVAASDGLAVLGVFLEIGDE-HRGLHKITDALYMVKFKGTVADFRDFNPKCLLPRSLGYWTYPGSLTTPPLYESVTWIVLAEPIEVSEKQMGKFRTLLFSGEEEEVRKRMENNFRPPQPLNGRAVRSNFQ 267

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BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Match: ca2 (carbonic anhydrase 1-like [Source:NCBI gene;Acc:103021731])

HSP 1 Score: 135.961 bits (341), Expect = 4.517e-37
Identity = 82/260 (31.54%), Postives = 135/260 (51.92%), Query Frame = 2

Query:  302 WG-QSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQ--FNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRAS-KNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            WG  + + P+ W      + G  QSP+ I T +  +D  L PL    D + +L+L  LN G  +Q  F  +  S ++ GGP+S  Y + +    +G +  +GS+H ++  TYP E+ +  +N   Y ++ +A+ K  G+A +  F +I  + N     L+ A E +  K    +       +LLP + ++ TY+GS+  PP  ESV WI+  + ISV+ TQM+  R L  S + +    + DN+RPPQ L  R +R + Q
Sbjct:    5 WGYAADNGPDKWVESFPVADGPRQSPIDIVTGEAEHDSALAPLAPHYDPSTSLDL--LNNGHSVQVTFADDTDSSSLTGGPISGTYRLKQFHFHWGSQDDKGSEHTVDGKTYPAELHLVHWNTT-YPSFGEAVDKPDGLAVIGVFLEIGDE-NPQLQKLLDAMEAIKSKGTQTSFADFDPTILLPGSLDYWTYDGSLTTPPLLESVTWIVCKQSISVSSTQMEKFRSLLFSGEGEPECCMMDNYRPPQPLKGRKVRASFQ 260

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BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Match: cahz (carbonic anhydrase-like [Source:NCBI gene;Acc:103030997])

HSP 1 Score: 127.102 bits (318), Expect = 1.119e-33
Identity = 82/267 (30.71%), Postives = 130/267 (48.69%), Query Frame = 2

Query:  263 WHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQ--FNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKN-DWSGIIADNFRPPQNLNRRAL 1054
            W Y   E  GP HW ++  +          + G  QSP+ I   Q  +D +L  L++  D + +  +  LN G   Q  F  +     + GGP++  Y + +    +G    RGS+H +    +P E+ +  +N   Y N+ +A+SK  G+A +  F KI   +N     ++ A + +  K    T        LLP+T ++ TYEGS+  PP +ESV WI+L +PISV+  QM   R L  S + +    + DN+RPPQ L  R +
Sbjct:    5 WGYS--EHDGPSHWCENFPV----------ANGPRQSPIDIIPSQAQFDSKLKQLKLKYDPSTSKGI--LNNGHSFQVDFADDDDRSVLTGGPVTGTYRLKQFHFHWGGADDRGSEHTVGGTKFPCELHLVHWN-TKYPNFGEAVSKPDGLAVVGVFLKIG-GANPSLQKVLDACDAIKSKGKQTTFSNFDPKTLLPATLQYWTYEGSLTTPPLHESVTWIVLRDPISVSPAQMAKFRSLLFSADGETPRCMVDNYRPPQPLKGRKV 255

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BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Match: ca8 (carbonic anhydrase VIII [Source:ZFIN;Acc:ZDB-GENE-050417-26])

HSP 1 Score: 136.732 bits (343), Expect = 6.111e-38
Identity = 75/245 (30.61%), Postives = 123/245 (50.20%), Query Frame = 2

Query:  359 GRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGG-PLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPST--KEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLR------ASKNDWSGIIADNFRPPQNLNRRALRTNI 1066
            G  QSP++I + +  +D  L    +        E + LN G  +  ++   SVT  G  P+  E+E+  I   +GK+  RGS+H +N   +P E  +  +N  LY N  DA+ K  GIA +  F +I  + +     L    + + YK    T+  +  + LLP    +++  YEGS+  PPC E+VLW++   P++++  Q++  R+LR      A  +   G + DNFRP Q LN R +R + 
Sbjct:   14 GENQSPININSREATFDPSLLTAPLCLSYLTCRECEVLNDGHSLHIHIRSKSVTTGGPFPIGQEFELSHICFHWGKEDQRGSEHTVNFKAFPMECHLIHWNATLYKNIEDAMGKENGIAIIALFVQIG-REHLGLKGLTDILQEIQYKGKAKTIPSLNPNTLLPDPLLRDYWVYEGSLTTPPCCENVLWLLFRYPLTLSHAQIEEFRRLRTHSKGVAPSDGCDGQLGDNFRPTQQLNDRVIRASF 257

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BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Match: CA2 (carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373])

HSP 1 Score: 114.39 bits (285), Expect = 1.020e-29
Identity = 73/264 (27.65%), Postives = 126/264 (47.73%), Query Frame = 2

Query:  284 VGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKG---SVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNI 1066
            + GPE WG         KH+     G  QSP+ I     +Y+  L  L +     +   +   N+G     + +     S  + GGPL+  Y++ +    +G   ++GS+H ++  +Y  E+ +  +N   Y+++ +A  K+ G+A L  F K+   +N     +  A   +  K      K     +LLP + +F +Y GS+  PP  ES +WI+L +PIS ++ Q+   R L+AS  D S ++  NFRP Q L  R ++ + 
Sbjct:   14 IAGPEVWG---------KHFKNAD-GSRQSPIDIEPASAVYEAALGALSVSYSGADAKSIS--NSGHSFSVDYDDSGDSSAVLSGGPLANPYKLKQFHFHWGASDAKGSEHTVDGKSYSAELHLVHWNAAKYASFDEAKDKSDGLAVLGAFVKVGA-NNAGLQKVTDALNAIADKGAKADFKNYDPSVLLPKSLDFWSYLGSLTTPPLNESAIWIVLKDPISASKEQLAAFRSLKAS--DGSKLVC-NFRPTQPLKGRVVQASF 261

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BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Match: CA10 (carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC:1369])

HSP 1 Score: 93.9745 bits (232), Expect = 1.848e-23
Identity = 46/105 (43.81%), Postives = 68/105 (64.76%), Query Frame = 2

Query:  788 VIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVC 1093
            + YK++   ++G+ ++ L P T  +ITYEGS+  PPCYE+V WI++N+P+ +T  QM +LR L  S+N  S I   + DNFRP Q L+ R +RTNI    + R C
Sbjct:   23 IAYKNDAYLLQGLSVEELYPDTSSYITYEGSMTTPPCYETVTWIVMNKPVYITHLQMHSLRLL--SQNLPSQIFLSMNDNFRPTQTLSSRCVRTNINFNFSGRDC 125

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BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006943.1 (pep scaffold:Pmarinus_7.0:GL476401:102791:181294:1 gene:ENSPMAG00000006261.1 transcript:ENSPMAT00000006943.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.8189 bits (229), Expect = 1.688e-20
Identity = 64/238 (26.89%), Postives = 118/238 (49.58%), Query Frame = 2

Query:  359 GRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNT-----GKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKS-SRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKD-NIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRK----LRASKNDWSGIIADNFRPPQNL 1039
            G  QSP+ IA++  +  + L+P +  E   E  ++ +  T     GK +  ++  G   ++GG L   Y +  +   +G  + + GS+H ++  ++P E+QIYGY++  +S+++ A+     +A+L   F+I   +N+ +  L+ A + V     ++        D+L  ST EF  Y G+   PPC + V W +    + ++  Q++ L      +RA        + DNFRPPQ L
Sbjct:   10 GERQSPIDIASE--VQAEVLSPADGLE--FEGWDVPSTTTTIKHDGKTVIVHL-SGDYHLRGGGLQGRYRMAWLTFHWGHSNGTEGSEHRLSGRSFPLEVQIYGYSQEHHSSFAAAMKAGGNMAALSILFEIAKDNNSAYIPLLEAVKRVCQPGIHVHATPFCASDLLPESTDEFFRYSGTTTTPPCAQGVEWTVFPRTVHISAHQLEALYGVLIMVRAGYAMLLEYLQDNFRPPQPL 242

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BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Match: ca4b (carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-080815-5])

HSP 1 Score: 88.5817 bits (218), Expect = 5.953e-20
Identity = 74/275 (26.91%), Postives = 124/275 (45.09%), Query Frame = 2

Query:  323 PEYW-KHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEI--FEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPS---TKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL-RASKNDWSGII-ADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSV 1123
            P  W K+   CS G  QSP+ I T  +  +  L  L+   ++ +   +     N G  +Q +++ G + + GG L   +   ++   +G     GS+H IN   +P E+ I  YN   Y  +  A ++  G+A L   + +   +N     + A   +V  +    TV    +D LLPS     ++  Y GS+  P C E V W +  EPI + E Q+K    +  ++K D   I+  +NFRP Q LN R +  +   T+   V  +   F ++ 
Sbjct:   38 PRTWYKNSPACS-GTSQSPIDIHTGSVKRNATLQKLKFIGYDSTPAGVTWSIQNNGHTVQVDLQ-GEIAVSGGGLPGTFNAVQMHFHWGNPHGPGSEHTINGKQFPVELHIVHYN-TKYLTFDGAKNEKDGLAVLGFLYAVGPTNNNYNTIINAL-PSVANQVTTRTVYMFNLDNLLPSYVNMSKYYRYSGSLTTPGCGEVVTWTVFEEPIIMDENQIKKFSSVFFSTKEDPQQILMVNNFRPVQKLNSRIVYASETATVGSAVPLVVNKFTHAA 308

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BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Match: EDO35860 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKA8])

HSP 1 Score: 136.346 bits (342), Expect = 1.251e-37
Identity = 88/267 (32.96%), Postives = 135/267 (50.56%), Query Frame = 2

Query:  290 GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEI--FEDSNENLELQALNTGKDIQFN-VEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDT----VKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            GP  W  S         ++ C+ G  QSP+ I T  + +D+ L  L+   F+      ++   N G   Q N +  G+ T+ GG L   Y   +  L +G K+ +GS+H+I+   + G I I  YN   Y N S A+ K+ G+A +    K+ T+S    AAL    EN+     ++T     +  K+  LLPS K F  Y+GS+  P C ESV W ++  PI+V+E Q+  LR L+  + D   +I DNFR    LN RA+++N +
Sbjct:    1 GPSKWSSS---------FSQCN-GSSQSPIDIITSSVAFDQSLGELQFVNFDTIPTGSKISLKNNGHAFQVNMLSAGTFTVSGGGLGATYSTVQFHLHWGSKNEQGSEHLIDGKAFAGAIHIVSYN-TKYPNISAAVDKSDGLAVVGILLKVGTES----AALKKFMENIGSVTKVNTSDEFAQPAKLGDLLPSNKNFYRYQGSLTTPGCQESVTWSVMANPITVSEAQLAILRGLK--QKDGVAVIQDNFRNTMPLNGRAVKSNFK 250

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BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Match: EDO46081 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR00])

HSP 1 Score: 124.405 bits (311), Expect = 5.727e-33
Identity = 83/272 (30.51%), Postives = 134/272 (49.26%), Query Frame = 2

Query:  263 WHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIK-GGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPS-TKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWS--GIIADNFRPPQNLNRRALRTNI 1066
            W Y   E  GP  W      P ++ H      G+MQSP++I T++  YD  LT L+I +  N    L   + G  I+ ++      +  G  LS  Y + +     G    +GS+H I+   YP E+ +  YN   Y N S A     G+A +   F+  +  N     +I   +N  YKD   TV+ + +  ++P+ T++F  Y GS+  PPC+E+V WI+L +  S++E Q++  R + ++    +    + DNFRP Q+LN R +R N 
Sbjct:    4 WSYD--EATGPSTW------PNHFPHCG----GKMQSPININTEEAKYDGSLTDLDI-KYPNTTDVLLVNHHGHAIEADILSSEPFVATGADLSSRYRLAQFHFHVGSSDIQGSEHHIHGVKYPLEMHLVHYNDK-YPNASSAQGLLDGLAVISVLFESSSTDNPALNEIIDNLQNASYKDEEITVQNVPVGKIIPTDTEKFYRYNGSLTTPPCFETVKWIVLKKTASISEKQLRQFRSVFSTSRQATKPNSLVDNFRPTQSLNGRIIRKNF 261

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BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Match: EDO40438 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S762])

HSP 1 Score: 116.316 bits (290), Expect = 3.292e-30
Identity = 76/249 (30.52%), Postives = 123/249 (49.40%), Query Frame = 2

Query:  341 WAWCSLGR---MQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGK-KSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKG-IKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQL 1072
            W  C +G     QSP+ I T  +  D  L  L    +   N  L   N G+ +Q      +  + GGPL+ EY++  I   +   + S GS+HMI++  +  E+Q+  +N+  Y N  +AI+   GI  L  FF++  ++N     ++    +++ KD    VK  I   +  P+  E+ TYEGS+  PP  E+V W+I    + ++E QM   R +R S  D   I+A N RP   +N R +R++  L
Sbjct:    5 WHKCYIGAEPGHQSPIDIVTKDVTQDSSLGSLWNTYEPVANSTL--TNDGRTLQLTFANNNNVLSGGPLTDEYQLAMIKFHWAATEESAGSEHMIDSQGHAIEVQLVHWNKTKYRNIGEAITGEQGICILAVFFQVGNEANEGLDVIV----DLLSKDEHKVVKAAIDPKIFFPAESEYWTYEGSLTTPPLTENVTWVICQSSLILSEDQMNVFRNIRNSHGD---IMAKNSRPVCPINGRTIRSSDTL 244

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BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Match: EDO45955 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH8])

HSP 1 Score: 109.768 bits (273), Expect = 8.854e-28
Identity = 74/263 (28.14%), Postives = 125/263 (47.53%), Query Frame = 2

Query:  290 GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEI--FEDSNENLELQALNTGKDIQFNVEKGSVT-IKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNI-DTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRP-PQNLNRRALRTN 1063
            GP+HW            +  C+ G  QSP++I T  ++YD  L  L+   F+      ++   N G   Q N    ++  + GG L   +   +  +  G+  +RG++H+I+       I I  YN   Y + S A +K+ G+A +    ++  + N   A ++   ENV    N+ D  +   +  LLPS  +F  Y+GS+  PPCYESV W ++    +++  Q+  LR +   + D    I DN+R   Q LN R +++N
Sbjct:    1 GPDHWAN---------RYPACN-GSSQSPINIVTSSVMYDSSLGKLQFNNFDRIPSGAKIMVRNNGHAFQVNFMTPNLFYVHGGGLGANFTTAQFHMHLGEDDTRGAEHLIDGQRNAACIHIVNYN-TKYPDISTAANKSDGLAVIGVILEVGAE-NAGLAKVLKYVENVTKVGNVSDLAQEFSLGSLLPSNTDFFRYKGSLTTPPCYESVTWTVMKTKTTISHDQLMKLRSIM--EKDGVHKITDNYRHILQPLNGRTVKSN 249

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BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Match: EDO42126 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2D8])

HSP 1 Score: 97.0561 bits (240), Expect = 2.161e-23
Identity = 68/254 (26.77%), Postives = 112/254 (44.09%), Query Frame = 2

Query:  320 MPEYWK-HWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVT----IKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNI 1066
            MP  W   +   + G+ QSP+ I +++  +D  + P+++  D     +L   NTG  + F+ E  +      I  GPLS++Y+  +    +GK    GS+H ++   YP E+ I  YN  LY + + A+S              D K       +    +   +  NI T     I +      E  TY GS+  PP  E V WI+L   I ++  Q+K    L+ +K +    I  N+RPP  L+ R ++   
Sbjct:    1 MPGKWSVKFPIAASGKRQSPIDIVSNETKFDSTIPPVKVHYDPFTKGKLT--NTGHSVSFSGESDASVPTPDITSGPLSHKYKFAQFHFHWGKDEKEGSEHRVDGKMYPSEMHIVHYNSDLYKDAASAMSS-------------DNKDGLCVLGVFLEVKEDAFLLNICTC---TIHLFFSCVLECWTYPGSLTTPPLSEIVNWIVLKNTIEISHHQLKLFHGLQNAKGE---CITHNYRPPCPLHGRVVKATF 233

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Match: ca10a (carbonic anhydrase 10 [Source:NCBI gene;Acc:101170880])

HSP 1 Score: 184.882 bits (468), Expect = 8.825e-55
Identity = 108/317 (34.07%), Postives = 167/317 (52.68%), Query Frame = 2

Query:  215 VSVTWASQLSKKWESWWHYKLKEVGG----PEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGS-VTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAAS--ENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI---IADNFRPPQNLNRRALRTNIQLTLTERVCRIER--DFFYSVND 1129
            V ++      K  E WW YK    G     P  WG   S       W  CS+G+ QSPV I T  +I+D  LTP+++       +     NTG+ +   ++K   V I GGP++Y + +  I L FG + S+GS+H++N   + GE+Q+  YN  LY+NY++A     G+  +  F KI   SN+    ++       + YK++   + G+ I+ + P T  FI+Y+GS+  PPC E+  WI++N+P+ +T  QM +LR L  S+N  S I   ++DN RP Q LN R +RTNI  ++  + C   R     Y VN+
Sbjct:   17 VCISAQPNPPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSA------WNLCSVGKRQSPVDIETSHMIFDPFLTPIKL-NTGGRKVGGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYANYTEAAKSPNGLVIVSIFMKIAETSNSFLNRMLNRDTITRITYKNDAYLLTGLNIEEIYPETSSFISYDGSMTIPPCSETATWILMNKPVYLTRMQMHSLRLL--SQNQPSQIFLSMSDNVRPVQPLNNRCIRTNINFSMQGKDCPNNRAQKLQYRVNE 324

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BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Match: ENSORLT00000031470.1 (carbonic anhydrase 1 [Source:NCBI gene;Acc:101168081])

HSP 1 Score: 132.109 bits (331), Expect = 1.252e-35
Identity = 83/263 (31.56%), Postives = 130/263 (49.43%), Query Frame = 2

Query:  290 GPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQ--FNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLR-ASKNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            GP+ WG++  + +          G  QSP+ I      YD  L PL +  D +  LE+  LN G  IQ  F  +    T+  GP+S  Y + +    +G    RGS+H +N   Y  E+ +  +N   Y+N+ +A SK  G+A +  F K+   +N +   L+ A   +  K +  +  G     LLP   ++ TY+GS+  PP  ESV WI+  EPISV+  QM   R L  +++ +    + DN+RPPQ L  R +R + +
Sbjct:   12 GPDKWGKNFPIAD----------GVRQSPIDIVPAAASYDGGLKPLCLKYDPSTCLEI--LNNGHSIQVTFIDDSDKSTLTNGPISGVYRLKQFHFHWGGADDRGSEHTVNGTKYAAELHLVHWN-TKYANFGEAASKPDGLAVVGVFLKVG-DANPNLQKLLDAFNGIKTKGSQTSFAGFDPATLLPGCLDYWTYDGSLTTPPLLESVTWIVCKEPISVSPGQMAKFRSLLFSAQGEAECCMVDNYRPPQPLKGRRVRASFK 260

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Match: cahz (carbonic anhydrase [Source:NCBI gene;Acc:101161087])

HSP 1 Score: 130.183 bits (326), Expect = 7.940e-35
Identity = 84/260 (32.31%), Postives = 129/260 (49.62%), Query Frame = 2

Query:  302 WGQSTS-MPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQ--FNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGI-IADNFRPPQNLNRRALRTNIQ 1069
            WG   S  PE W      + G  QSP++I   +  +D  L PL+I  D+ +   +  LN G   Q  F  +  S T+ GGP+S  Y + +    +G    RGS+H IN  T+P E+ +  +N   Y+++ +A  K  G+A +  F KI   +N     ++ A + +  K   +         LLP + ++ TY+GS+  PP  ESV WI+L E ISV+  QM   R L  + +      + DNFRPPQ L  R +R + +
Sbjct:    5 WGYGPSDGPETWAENFPLASGPRQSPINIVPKEAQFDPSLKPLKIRYDARDAKGI--LNNGHSFQVDFVDDTDSSTLTGGPISGTYRLKQFHFHWGASDERGSEHTINGITFPCELHLVHWN-TKYASFGEAADKPDGLAVVGVFLKIGA-ANPKLQKVLDALDAIKTKGKQNVFANFDPKTLLPGSLDYWTYDGSLTTPPLLESVTWIVLKEQISVSPAQMAKFRSLLFTGDGEPLCNMVDNFRPPQLLKGRRVRASFK 260

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Match: ca7 (carbonic anhydrase 7 [Source:NCBI gene;Acc:101170576])

HSP 1 Score: 128.257 bits (321), Expect = 4.326e-34
Identity = 78/260 (30.00%), Postives = 128/260 (49.23%), Query Frame = 2

Query:  296 EHWGQSTS-MPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIA-ASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKL--RASKNDWSGIIADNFRPPQNLNRRALRTN 1063
             HWG      P  W      + G  QSP+ I   Q + D+ L P+ +  D   ++ +        ++F+       I+GGPL   Y + +    +G K   GS+H ++ + Y  E+ +  +N V Y ++ +A +   G+A L  F  ++T  +  +  +I  A   V +K +    KG     LLPS+  + TY GS+  PP +ESV+WI+L EPI+V+E Q+   R L     + D    + +NFRPPQ L  R +R++
Sbjct:    4 HHWGYGEGDGPSAWHKNYPVAQGSRQSPIDIIPHQALQDRSLGPIVLNYDHCTSINISNNGHSVVVEFDDSDDRSVIQGGPLDNPYRLKQFHFHWGGKGCEGSEHTVDGYGYASELHLVHWNAVKYCSFGEASTAPDGLAVLGIF--LETGDDHRWLHMITDALYMVKFKGSGTEFKGFNPKCLLPSSLHYWTYLGSLTTPPLHESVIWIVLKEPIAVSEKQLGKFRLLLFTGEEEDQRTRMENNFRPPQPLKGRKVRSS 261

[Close]

BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Match: ca8 (carbonic anhydrase 8 [Source:NCBI gene;Acc:101174864])

HSP 1 Score: 122.479 bits (306), Expect = 9.061e-32
Identity = 68/249 (27.31%), Postives = 133/249 (53.41%), Query Frame = 2

Query:  359 GRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPL--SYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPST--KEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRA--------SKNDWSGIIADNFRPPQNLNRRALRTNIQ 1069
            G  QSP+++ + +  YD  L  + +  +     + + +N G  ++  ++  SV + GGPL   +EYE++ +   +GK++ RGS+H +N   +P E+ +  +N  L+++  DA+ +  G+  +  F ++  K +    A+    +++ YK     +     + LLP    +++  Y+GS+  PPC E+V WI+   P+++++ Q++  R+LR+          ND  G++ DNFRP Q L+ R +R   Q
Sbjct:   37 GEYQSPINLNSREAQYDPSLLDVGLSPNYVVCRDCEVVNDGHTVRILLKSKSV-VTGGPLPSDHEYELHEVRFHWGKENQRGSEHTVNFKAFPMELHLIHWNSTLFNSLEDALGRKNGVLIIALFVQV-GKEHLGLKAITEVLQDLQYKGKSKIIPCFNPNTLLPDPLLRDYWVYDGSLTTPPCSENVTWILYRYPLTISQMQIEEFRRLRSHVKGAELLEGND--GMLGDNFRPTQPLSDRTVRAAFQ 281

[Close]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Match: SMESG000054330.1 (SMESG000054330.1)

HSP 1 Score: 653.67 bits (1685), Expect = 0.000e+0
Identity = 314/315 (99.68%), Postives = 315/315 (100.00%), Query Frame = 2

Query:  188 MIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVNDP 1132
            MIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYS+AISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVNDP
Sbjct:    1 MIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSEAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVNDP 315

[Close]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Match: SMESG000056463.1 (SMESG000056463.1)

HSP 1 Score: 280.411 bits (716), Expect = 4.954e-92
Identity = 133/316 (42.09%), Postives = 209/316 (66.14%), Query Frame = 2

Query:  185 SMIIYVFFSIVSVTWASQL-SKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFN-VEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVN 1126
            +++  +  +  +  W SQ  + KW++ WHYK  ++GGP+ WG    M    K W  C+ G  QSP++I+ D+L+YD  LTP+ +F   N+++EL   N G+D+  +     ++TI GGPLSY ++ + +L+KFG  SSRGSDH IN  ++PGE+Q YG+N  +Y N S A++K YG+A++  F KI   S+ D  ALI  +E  + K +   + G+++  L+P+  ++ITY GS+P P C E+V WIILN+ + VTE+Q+K+LR+L+ S ++ SG +ADNFRP Q+L+ RA+RTNI+L    ++C  ++DF+Y VN
Sbjct:   10 ALVSMILVNSANQIWRSQEWNSKWDAKWHYKPGDIGGPQQWGHLYLMSHENK-WMSCNKGHNQSPINISLDKLLYDPMLTPISVF-GGNQSIELSIDNMGQDLTASQTSNENITISGGPLSYSFKFFSLLIKFGSLSSRGSDHKINGMSFPGELQFYGFNHEIYDNISHALNKPYGLAAISVFLKIGKTSSDDLKALIQTAEKCVIKGSQKFLNGLQLSRLMPNVDQYITYPGSLPFPGCDETVTWIILNQHLDVTESQLKSLRQLKLSISENSGRMADNFRPIQSLHNRAIRTNIRLHQQTKICDFKQDFYYEVN 323

[Close]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Match: SMESG000056463.1 (SMESG000056463.1)

HSP 1 Score: 279.256 bits (713), Expect = 9.863e-92
Identity = 133/302 (44.04%), Postives = 203/302 (67.22%), Query Frame = 2

Query:  227 WASQL-SKKWESWWHYKLKEVGGPEHWGQSTSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKDIQFN-VEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTERVCRIERDFFYSVN 1126
            W SQ  + KW++ WHYK  ++GGP+ WG    M    K W  C+ G  QSP++I+ D+L+YD  LTP+ +F   N+++EL   N G+D+  +     ++TI GGPLSY ++ + +L+KFG  SSRGSDH IN  ++PGE+Q YG+N  +Y N S A++K YG+A++  F KI   S+ D  ALI  +E  + K +   + G+++  L+P+  ++ITY GS+P P C E+V WIILN+ + VTE+Q+K+LR+L+ S ++ SG +ADNFRP Q+L+ RA+RTNI+L    ++C  ++DF+Y VN
Sbjct:   11 WRSQEWNSKWDAKWHYKPGDIGGPQQWGHLYLMSHENK-WMSCNKGHNQSPINISLDKLLYDPMLTPISVF-GGNQSIELSIDNMGQDLTASQTSNENITISGGPLSYSFKFFSLLIKFGSLSSRGSDHKINGMSFPGELQFYGFNHEIYDNISHALNKPYGLAAISVFLKIGKTSSDDLKALIQTAEKCVIKGSQKFLNGLQLSRLMPNVDQYITYPGSLPFPGCDETVTWIILNQHLDVTESQLKSLRQLKLSISENSGRMADNFRPIQSLHNRAIRTNIRLHQQTKICDFKQDFYYEVN 310

[Close]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Match: SMESG000022420.1 (SMESG000022420.1)

HSP 1 Score: 114.775 bits (286), Expect = 3.065e-29
Identity = 80/265 (30.19%), Postives = 130/265 (49.06%), Query Frame = 2

Query:  296 EHWGQS-TSMPEYWKHWAWCSLGRMQSPVSIATDQLIYDKQLT--PLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYE--YEVYRILLKFGKKSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVIYK--DNIDTVKGIKIDMLLPST-KEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNI 1066
            E WG    + P  W      + G  QSP++I   Q  YD  L   PL+I  DS+       + TG + + + E G++   GGP+ Y   Y++ +I+  +G     GS+H+IN F +P E Q+  YN   Y  +++A++K  G+  L     I  K+ T    L   +    +K  D     + + +  LLP     + TY GS+  PPCYE+V WII     +++E Q+  ++K+  + +  +G   DNFRP  +L +R +  N 
Sbjct:    4 EDWGYGPENGPHLWHKSYSSAGGCSQSPINIDLSQTKYDMTLNLHPLKICIDSSRTSSQTLVFTGHNFRIDCE-GALCASGGPIPYGQMYKISQIVFHWGSTIYGGSEHLINCFQFPCECQMTCYNATRYRCFNEAVNKRDGLIILSTMMHIGNKNKTLDRLLGPLTSIHFFKHHDFRQETELLDLKCLLPDCINRYFTYTGSLTTPPCYETVTWIIFEGSNTISEDQLNLMQKVHVA-DGCNGF--DNFRPVCSLGQRIITRNF 264

[Close]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Match: SMESG000078341.1 (SMESG000078341.1)

HSP 1 Score: 106.301 bits (264), Expect = 3.732e-26
Identity = 77/255 (30.20%), Postives = 130/255 (50.98%), Query Frame = 2

Query:  323 PEYWKHWAWCSLGRMQSPVSIATDQLIYDKQL--TPLEIFEDSNENLELQALNTGKDIQFNVEKGSVTIKGGPLSYEYEVYRIL---LKFGK-KSSRGSDHMINNFTYPGEIQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASENVI--YKDNI-DTVKGIKIDMLLP-STKEFITYEGSIPHPPCYESVLWIILNEPISVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALR 1057
            PE WK     + G  QSP++I  ++  ++ +L    L I  +S+ + E    +TG   +      S+T+   P  +  +V++++     +G   +  GS+H IN  ++P E+ +  YN   YSN+++A +K  G+  L  F +I  K N +F   I   E +    K N+ D    I +  LLP +T  + TY GS+  PPCYESV WI+   PI+++  Q++  RK+ +     +   A NFRP   +N R ++
Sbjct:   12 PETWKMSYPAAKGDSQSPINIIVNKTEFESELFQKKLNIKINSDYSAEQILNHTGHSFKVETSVDSMTVTNAP-GFNNDVFKLVQFHFHWGSIGNDNGSEHQINGKSWPSELHLVHYNSTKYSNFTEAANKPDGLLVLGVFIQIAGK-NLEFQNFIQCLETIQADLKVNLKDKNSKINLKYLLPINTDRYFTYSGSLTTPPCYESVTWIVFEYPITMSREQIERFRKVHSEDGCET---AANFRPVCPINDRKVK 261

The following BLAST results are available for this feature:

BLAST of Carbonic anhydrase-related vs. Ensembl Human
BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
BLAST of Carbonic anhydrase-related vs. Ensembl Fly
BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
BLAST of Carbonic anhydrase-related vs. TrEMBL
BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
BLAST of Carbonic anhydrase-related vs. Ensembl Yeast
BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
BLAST of Carbonic anhydrase-related vs. Planmine SMEST

BLAST of Carbonic anhydrase-related vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CA10	4.917e-59	36.16	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
CA10	4.917e-59	36.16	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
CA10	4.917e-59	36.16	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
CA10	5.997e-49	34.59	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
CA11	1.121e-47	33.68	carbonic anhydrase 11 [Source:HGNC Symbol;Acc:HGNC...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cah-1	7.330e-48	33.67	Putative carbonic anhydrase-like protein 1 [Sourc...	[more]
cah-2	1.406e-43	31.99	Putative carbonic anhydrase-like protein 2 [Sourc...	[more]
cah-1	9.327e-36	37.76	Putative carbonic anhydrase-like protein 1 [Sourc...	[more]
cah-5	3.264e-19	25.84	Putative carbonic anhydrase 5 [Source:UniProtKB/S...	[more]
cah-3	3.161e-18	24.22	Putative carbonic anhydrase 3 [Source:UniProtKB/S...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CARPA	2.543e-62	34.15	gene:FBgn0029962 transcript:FBtr0343348	[more]
CARPA	2.543e-62	34.15	gene:FBgn0029962 transcript:FBtr0300019	[more]
CARPB	2.576e-58	35.49	gene:FBgn0052698 transcript:FBtr0346170	[more]
CARPB	2.576e-58	35.49	gene:FBgn0052698 transcript:FBtr0336923	[more]
CARPB	2.576e-58	35.49	gene:FBgn0052698 transcript:FBtr0307489	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ca10b	1.087e-58	37.76	carbonic anhydrase Xb [Source:ZFIN;Acc:ZDB-GENE-08...	[more]
ca10a	1.172e-57	35.53	carbonic anhydrase Xa [Source:ZFIN;Acc:ZDB-GENE-05...	[more]
ca10a	1.172e-57	35.53	carbonic anhydrase Xa [Source:ZFIN;Acc:ZDB-GENE-05...	[more]
ca10a	2.346e-45	37.00	carbonic anhydrase Xa [Source:ZFIN;Acc:ZDB-GENE-05...	[more]
ca2	3.004e-37	29.37	carbonic anhydrase II [Source:ZFIN;Acc:ZDB-GENE-03...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CA10	5.239e-58	37.04	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
CA11	1.041e-54	33.87	carbonic anhydrase XI [Source:NCBI gene;Acc:100493...	[more]
CA11	4.520e-54	34.92	carbonic anhydrase XI [Source:NCBI gene;Acc:100493...	[more]
ca8	3.286e-38	31.58	carbonic anhydrase VIII [Source:NCBI gene;Acc:4966...	[more]
proca1	2.756e-33	28.85	protein interacting with cyclin A1 [Source:Xenbase...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Car10	3.376e-59	36.16	carbonic anhydrase 10 [Source:MGI Symbol;Acc:MGI:1...	[more]
Car10	3.376e-59	36.16	carbonic anhydrase 10 [Source:MGI Symbol;Acc:MGI:1...	[more]
Car10	6.528e-53	34.91	carbonic anhydrase 10 [Source:MGI Symbol;Acc:MGI:1...	[more]
Car11	5.397e-47	31.15	carbonic anhydrase 11 [Source:MGI Symbol;Acc:MGI:1...	[more]
Car7	3.850e-38	31.66	carbonic anhydrase 7 [Source:MGI Symbol;Acc:MGI:10...	[more]

BLAST of Carbonic anhydrase-related vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|A0JN41\|CAH10_BOVIN	1.430e-58	36.16	Carbonic anhydrase-related protein 10 OS=Bos tauru...	[more]
sp\|Q5R4U0\|CAH10_PONAB	2.361e-58	36.16	Carbonic anhydrase-related protein 10 OS=Pongo abe...	[more]
sp\|P61215\|CAH10_MOUSE	2.361e-58	36.16	Carbonic anhydrase-related protein 10 OS=Mus muscu...	[more]
sp\|Q9N085\|CAH10_MACFA	2.361e-58	36.16	Carbonic anhydrase-related protein 10 OS=Macaca fa...	[more]
sp\|Q9NS85\|CAH10_HUMAN	2.361e-58	36.16	Carbonic anhydrase-related protein 10 OS=Homo sapi...	[more]

BLAST of Carbonic anhydrase-related vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4E0RAH6	1.226e-89	43.58	Carbonic anhydrase XIII OS=Fasciola hepatica OX=61...	[more]
G4VIP7	4.785e-87	41.67	Carbonic anhydrase-related OS=Schistosoma mansoni ...	[more]
A0A3R7ESL3	1.144e-85	41.10	Carbonic anhydrase-related protein 10 (Fragment) O...	[more]
A0A504YCI5	3.764e-85	45.29	Carbonic anhydrase XIII OS=Fasciola gigantica OX=4...	[more]
G7YJ22	7.807e-85	41.58	Carbonic anhydrase-related protein 10 (Fragment) O...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ca10b	1.866e-49	37.04	carbonic anhydrase Xb [Source:ZFIN;Acc:ZDB-GENE-08...	[more]
ca7	6.793e-38	30.26	carbonic anhydrase 7 [Source:NCBI gene;Acc:1030418...	[more]
ca7	9.855e-38	30.15	carbonic anhydrase 7 [Source:NCBI gene;Acc:1030418...	[more]
ca2	4.517e-37	31.54	carbonic anhydrase 1-like [Source:NCBI gene;Acc:10...	[more]
cahz	1.119e-33	30.71	carbonic anhydrase-like [Source:NCBI gene;Acc:1030...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ca8	6.111e-38	30.61	carbonic anhydrase VIII [Source:ZFIN;Acc:ZDB-GENE-...	[more]
CA2	1.020e-29	27.65	carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
CA10	1.848e-23	43.81	carbonic anhydrase 10 [Source:HGNC Symbol;Acc:HGNC...	[more]
ENSPMAT00000006943.1	1.688e-20	26.89	pep scaffold:Pmarinus_7.0:GL476401:102791:181294:1...	[more]
ca4b	5.953e-20	26.91	carbonic anhydrase IV b [Source:ZFIN;Acc:ZDB-GENE-...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Carbonic anhydrase-related vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO35860	1.251e-37	32.96	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46081	5.727e-33	30.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO40438	3.292e-30	30.52	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45955	8.854e-28	28.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42126	2.161e-23	26.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Carbonic anhydrase-related vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ca10a	8.825e-55	34.07	carbonic anhydrase 10 [Source:NCBI gene;Acc:101170...	[more]
ENSORLT00000031470.1	1.252e-35	31.56	carbonic anhydrase 1 [Source:NCBI gene;Acc:1011680...	[more]
cahz	7.940e-35	32.31	carbonic anhydrase [Source:NCBI gene;Acc:101161087...	[more]
ca7	4.326e-34	30.00	carbonic anhydrase 7 [Source:NCBI gene;Acc:1011705...	[more]
ca8	9.061e-32	27.31	carbonic anhydrase 8 [Source:NCBI gene;Acc:1011748...	[more]

BLAST of Carbonic anhydrase-related vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000054330.1	0.000e+0	99.68	SMESG000054330.1	[more]
SMESG000056463.1	4.954e-92	42.09	SMESG000056463.1	[more]
SMESG000056463.1	9.863e-92	44.04	SMESG000056463.1	[more]
SMESG000022420.1	3.065e-29	30.19	SMESG000022420.1	[more]
SMESG000078341.1	3.732e-26	30.20	SMESG000078341.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001341 ID=SMED30001341|Name=Carbonic anhydrase-related|organism=Schmidtea mediterranea sexual|type=transcript|length=1209bp
TAACATTTAGTTTGACATTCAGATAGTAAATCGTCCAATCAACGCGCGAA
AAATAAACAACCAATCAATTGATTTCAAATTTGAAGATTTAATTATATAT
AAAAATTAGAACATTAATCAAACTGGTCGTCAAAAAAATGCAAACATTAT
AATAATTTACCATGCTAAAATATCCATTGATTCCTCTATGATTATCTATG
TCTTTTTCAGTATTGTATCAGTCACCTGGGCATCACAGCTGAGTAAGAAG
TGGGAGTCCTGGTGGCATTACAAGTTGAAAGAAGTAGGAGGACCAGAACA
TTGGGGCCAATCGACTAGCATGCCAGAGTACTGGAAACATTGGGCTTGGT
GTTCATTGGGAAGAATGCAGTCACCTGTCTCTATTGCCACCGACCAGTTG
ATTTATGACAAGCAATTAACTCCTTTAGAAATATTTGAAGATTCTAATGA
AAATCTAGAGCTTCAAGCATTGAATACGGGTAAAGACATTCAATTCAATG
TTGAAAAGGGTTCAGTGACTATCAAAGGAGGTCCATTATCGTATGAATAT
GAGGTGTATCGAATTTTATTGAAATTTGGTAAAAAATCCTCTAGAGGATC
TGACCACATGATTAATAACTTCACTTATCCTGGAGAAATTCAAATTTATG
GTTATAATCGAGTTTTATATTCAAACTATTCAGACGCTATTAGTAAGACG
TATGGAATAGCAAGTTTAGTGTGCTTTTTTAAGATTGATACCAAATCCAA
TACAGATTTTGCTGCCTTGATTGCTGCTTCTGAGAATGTTATTTACAAAG
ATAATATCGACACAGTCAAGGGAATAAAAATTGACATGCTTCTTCCTTCT
ACCAAAGAATTCATCACGTATGAAGGCTCAATTCCTCATCCTCCATGCTA
CGAAAGTGTTTTATGGATCATCCTAAATGAACCTATTAGTGTTACAGAAA
CTCAGATGAAAACTCTCAGAAAATTGCGAGCATCAAAGAACGATTGGTCA
GGAATCATTGCCGATAATTTTCGACCACCTCAAAATCTCAATCGTCGAGC
TCTCCGAACAAATATCCAACTTACTCTGACGGAAAGAGTATGCAGAATTG
AACGAGATTTCTTTTATTCTGTAAATGATCCATAAATTTAACAGAAACAA
CATTCCAAAAAATAATTATTCTCGTGGAGTAAAAAGAGGCACTTTGTAAA
TATACCAAA

protein sequence of SMED30001341-orf-1

>SMED30001341-orf-1 ID=SMED30001341-orf-1|Name=SMED30001341-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=316bp
MIIYVFFSIVSVTWASQLSKKWESWWHYKLKEVGGPEHWGQSTSMPEYWK
HWAWCSLGRMQSPVSIATDQLIYDKQLTPLEIFEDSNENLELQALNTGKD
IQFNVEKGSVTIKGGPLSYEYEVYRILLKFGKKSSRGSDHMINNFTYPGE
IQIYGYNRVLYSNYSDAISKTYGIASLVCFFKIDTKSNTDFAALIAASEN
VIYKDNIDTVKGIKIDMLLPSTKEFITYEGSIPHPPCYESVLWIILNEPI
SVTETQMKTLRKLRASKNDWSGIIADNFRPPQNLNRRALRTNIQLTLTER
VCRIERDFFYSVNDP*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0004089	carbonate dehydratase activity
GO:0008270	zinc ion binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR036398	CA_dom_sf
IPR023561	Carbonic_anhydrase_a-class
IPR018347	CAH2
IPR001148	CA_dom

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001148	Alpha carbonic anhydrase domain	SMART	SM01057	Carb_anhydrase_2a	coord: 39..293 e-value: 1.3E-66 score: 237.3
IPR001148	Alpha carbonic anhydrase domain	PFAM	PF00194	Carb_anhydrase	coord: 38..291 e-value: 3.4E-63 score: 213.6
IPR001148	Alpha carbonic anhydrase domain	PROSITE	PS51144	ALPHA_CA_2	coord: 24..293 score: 50.194
IPR036398	Alpha carbonic anhydrase domain superfamily	GENE3D	G3DSA:3.10.200.10		coord: 19..291 e-value: 3.1E-67 score: 228.8
IPR036398	Alpha carbonic anhydrase domain superfamily	SUPERFAMILY	SSF51069	Carbonic anhydrase	coord: 26..291
IPR023561	Carbonic anhydrase, alpha-class	PANTHER	PTHR18952	CARBONIC ANHYDRASE	coord: 25..298
IPR018347	Putative carbonic anhydrase-like protein 2	PANTHER	PTHR18952:SF138	CARBONIC ANHYDRASE XA-RELATED	coord: 25..298
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..15 score: 0.722

Main menu

Carbonic anhydrase-related

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

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