slc24a-8
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001319 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of slc24a-8 vs. Ensembl Human
Match: SLC24A5 (solute carrier family 24 member 5 [Source:HGNC Symbol;Acc:HGNC:20611]) HSP 1 Score: 353.599 bits (906), Expect = 6.926e-116 Identity = 201/460 (43.70%), Postives = 292/460 (63.48%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQR-----------LPR-----LKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP F TR+ER++GGII + + +Y+F+A++I+CDEYF+ SLE + E + DVAG TFMAAGSSAPEL T+ +GVFITK D+GISTI+GSA++N+L I A CG+ +V L+ WP+FRDC Y +S A++ I+ D + WYE ++L +Y Y+++L ++ + ++I++ + R L G+ +E P I + T G+ + S+H ++ ED P++F +P + R++WV LP+ + + T PDCRK W+ F++TFF+S IWIS TYILVWM+ + G+TL+IPDT+MGLT LAAGTSIPD IA LVA+ G GDMA+SN +GSNVFD+L CLG+PWFI+T+F+N + V S L + TI+L +++ L + N WKL+R LG + L Y+ + LS L+EL I+GN
Sbjct: 45 QCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSI----SLHGLSQVSED------PPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKK-FWKNYFVITFFMSAIWISAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPWFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGLATLSVLYELGIIGN 492
BLAST of slc24a-8 vs. Ensembl Human
Match: SLC24A5 (solute carrier family 24 member 5 [Source:HGNC Symbol;Acc:HGNC:20611]) HSP 1 Score: 293.123 bits (749), Expect = 2.657e-93 Identity = 175/404 (43.32%), Postives = 253/404 (62.62%), Query Frame = 1
Query: 400 VFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQR-----------LPR-----LKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
+ DVAG TFMAAGSSAPEL T+ +GVFITK D+GISTI+GSA++N+L I A CG+ +V L+ WP+FRDC Y +S A++ I+ D + WYE ++L +Y Y+++L ++ + ++I++ + R L G+ +E P I + T G+ + S+H ++ ED P++F +P + R++WV LP+ + + T PDCRK W+ F++TFF+S IWIS TYILVWM+ + G+TL+IPDT+MGLT LAAGTSIPD IA LVA+ G GDMA+SN +GSNVFD+L CLG+PWFI+T+F+N + V S L + TI+L +++ L + N WKL+R LG + L Y+ + LS L+EL I+GN
Sbjct: 41 ALGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSI----SLHGLSQVSED------PPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKK-FWKNYFVITFFMSAIWISAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPWFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGLATLSVLYELGIIGN 432
BLAST of slc24a-8 vs. Ensembl Human
Match: SLC24A3 (solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977]) HSP 1 Score: 191.045 bits (484), Expect = 1.048e-52 Identity = 95/165 (57.58%), Postives = 129/165 (78.18%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
KNCT ++ EFPND T ++R+ G ++ H+ +IY+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSSAPEL TSVIGVFITK DVG+ TIVGSAVFN+LCII +CG+F G V+ L+ W + RD I Y LS+IALI+ + D + W+E+L+++ MY+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYL 249 HSP 2 Score: 173.711 bits (439), Expect = 2.079e-46 Identity = 98/207 (47.34%), Postives = 138/207 (66.67%), Query Frame = 1
Query: 961 TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
T F+ P+ + W P++ + YFT+P+C KP W K F+VTF S +WI+ +Y++VWM+ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSNVFDILI LGLPW ++T ++ GS I + S LI++ LL++V V V + +NKW+L++ LG L LY + + S + E N+ N P C
Sbjct: 436 TPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPR-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMC 641
BLAST of slc24a-8 vs. Ensembl Human
Match: SLC24A3 (solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977]) HSP 1 Score: 191.045 bits (484), Expect = 1.048e-52 Identity = 95/165 (57.58%), Postives = 129/165 (78.18%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
KNCT ++ EFPND T ++R+ G ++ H+ +IY+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSSAPEL TSVIGVFITK DVG+ TIVGSAVFN+LCII +CG+F G V+ L+ W + RD I Y LS+IALI+ + D + W+E+L+++ MY+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYL 249 HSP 2 Score: 173.711 bits (439), Expect = 2.079e-46 Identity = 98/207 (47.34%), Postives = 138/207 (66.67%), Query Frame = 1
Query: 961 TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
T F+ P+ + W P++ + YFT+P+C KP W K F+VTF S +WI+ +Y++VWM+ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSNVFDILI LGLPW ++T ++ GS I + S LI++ LL++V V V + +NKW+L++ LG L LY + + S + E N+ N P C
Sbjct: 436 TPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPR-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMC 641
BLAST of slc24a-8 vs. Ensembl Human
Match: SLC24A4 (solute carrier family 24 member 4 [Source:HGNC Symbol;Acc:HGNC:10978]) HSP 1 Score: 189.504 bits (480), Expect = 2.172e-52 Identity = 96/183 (52.46%), Postives = 131/183 (71.58%), Query Frame = 1
Query: 175 NSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
N M+ ++GT KNCT +I EFP D + KER++G ++ HI ++Y+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSS PEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CG+F G V+ L WW + RD + Y +S+I LI+ + D I W+E L+++ +YV
Sbjct: 61 NRKLMAPVNGTQTA----KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYV 239 HSP 2 Score: 177.948 bits (450), Expect = 3.334e-48 Identity = 95/205 (46.34%), Postives = 137/205 (66.83%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F VP + ++ WV P+ + TIP+C KP W K F+VTF + +WI+V +YI+VW++ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + + S L+++ + LL +V + V I +NKW+L+R LG L LY + + S + E N+ N P C
Sbjct: 396 FSVPEARGDKVKWVFTWPLIFLLCVTIPNCSKPR-WEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEFNVFTFVNLPMC 599
BLAST of slc24a-8 vs. Ensembl Celegans
Match: ncx-5 (Na/Ca eXchangers [Source:UniProtKB/TrEMBL;Acc:G5EC02]) HSP 1 Score: 169.088 bits (427), Expect = 3.279e-45 Identity = 96/198 (48.48%), Postives = 130/198 (65.66%), Query Frame = 1
Query: 226 LKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNP 819
++ + + +FP D + + R+ GG+I HI + IY+FVALA++CDE+FV SL + EV I DVAGATFMAAG SAPE TS+ GVF+ + +VG+ TIVGSA FN+LC++A C +F V+HL WWP+FRD Y LS+ L+I D +I+W EAL+M MY+AY + +NG L Q L R G G E P
Sbjct: 73 IQTTSNANSSQFPADIFSLQTRRRGGVIVHIGLLIYMFVALAVVCDEFFVPSLSVITEVLAISDDVAGATFMAAGGSAPEFFTSLFGVFVAQDNVGVGTIVGSATFNILCVLAFCTLFSRQVLHLTWWPLFRDMSFYTLSLFLLLIFFGDEVIEWQEALVMFSMYIAYGFFMKFNGFLELKTKQFLFRKVGIGSEIAP 270 HSP 2 Score: 130.568 bits (327), Expect = 5.755e-32 Identity = 73/195 (37.44%), Postives = 118/195 (60.51%), Query Frame = 1
Query: 940 TNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSF----LNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALY 1512
++ E P P + +L ++ + P+ +T+PD RKP + RK F +TF +++WI+ +Y++VW IG+T IP IMGLT LAAGTSIPD I +VA+ G GDMA+S+SIGSN+FD+ + L +PW I + P I V S+ L+ + L + ++VL+ + +++WK+++F G + + Y
Sbjct: 440 SSTAEKPLDLSWPEANHKKLIYLFLAPITFPLAYTLPDVRKPSL-RKFFAITFIGAILWIAAYSYLMVWWANTIGETFGIPTEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSIGSNLFDVCVGLPIPWLIHFAIGVFKSEPTQNISVTSNGLVCSLGLLFAMLIVLLTCVAISRWKMDKFFGLLMIFSY 633
BLAST of slc24a-8 vs. Ensembl Celegans
Match: ncx-4 (Na/Ca eXchangers [Source:UniProtKB/TrEMBL;Acc:Q1ZXT5]) HSP 1 Score: 155.606 bits (392), Expect = 9.530e-41 Identity = 81/156 (51.92%), Postives = 113/156 (72.44%), Query Frame = 1
Query: 256 EFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
+FP D + ++R+NG ++ H+ IY+FV+LAI+CDE+FV SL+ L E ++ DVAGATFMAAG SAPE TSVIGVFI +++VGI TIVGSA FN+LC++A C +F S++ L WWP+FRD IY L++ L+ D +I + EAL M +Y+
Sbjct: 86 QFPPDPFSLEQRQNGFVVLHMCGLIYMFVSLAIVCDEFFVPSLDVLTEKLSLSDDVAGATFMAAGGSAPEFFTSVIGVFIAQNNVGIGTIVGSATFNILCVLAFCTLFSKSILDLTWWPLFRDVSIYMLALAMLVFFFMDEMITFPEALAMFSIYI 241 HSP 2 Score: 125.176 bits (313), Expect = 3.317e-30 Identity = 85/232 (36.64%), Postives = 125/232 (53.88%), Query Frame = 1
Query: 886 ETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFL--------NPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNIL 1557
+ ++ I S + E E P P ++ RL +V + PV + TIPD RK R L+ TF IS++WI+ +Y++VW IG+T IP I+GLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FD+ + L +PW + FL P S I V S L+ + L ++VLV I ++ WK+N+ G + + Y+ S E + L
Sbjct: 366 RSSQIEEIKSLLEEQE------EKPLDMTWPETWVKRLTYVLLAPVVIPMWVTIPDVRKSHN-RGLYPATFIISILWIAFFSYLMVWWANTIGETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLLY--FLIEYIKHPNEPLSPISVSSKGLLCSVGMLFIMLIVLVFAIFLSGWKMNKIFGILMIVSYVFFCVFSVSLETDKL 588
BLAST of slc24a-8 vs. Ensembl Celegans
Match: ncx-4 (Na/Ca eXchangers [Source:UniProtKB/TrEMBL;Acc:Q1ZXT5]) HSP 1 Score: 85.8853 bits (211), Expect = 1.470e-19 Identity = 59/148 (39.86%), Postives = 84/148 (56.76%), Query Frame = 1
Query: 1138 LVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFL--------NPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNIL 1557
+VW IG+T IP I+GLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FD+ + L +PW + FL P S I V S L+ + L ++VLV I ++ WK+N+ G + + Y+ S E + L
Sbjct: 1 MVWWANTIGETFVIPTEIIGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDVCVGLPIPWLLY--FLIEYIKHPNEPLSPISVSSKGLLCSVGMLFIMLIVLVFAIFLSGWKMNKIFGILMIVSYVFFCVFSVSLETDKL 146
BLAST of slc24a-8 vs. Ensembl Celegans
Match: ncx-6 (Putative sodium/calcium exchanger 6 [Source:UniProtKB/Swiss-Prot;Acc:P34315]) HSP 1 Score: 61.6178 bits (148), Expect = 9.755e-10 Identity = 39/115 (33.91%), Postives = 67/115 (58.26%), Query Frame = 1
Query: 1006 VAMLPVAAICYFTIPDCRKPGIWRKLF-LVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFI 1347
+++L AA+ +FT ++P ++ L F +S+ WI + + +V ++ ++G + ++GLT LA SI D IA VAK GY MA++ +IG +F++LI GLP+ I
Sbjct: 406 LSVLLTAAVLFFT-ELHKEPPFYKSLISYAGFLMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVAKQGYPRMAMAAAIGGQLFNLLIGFGLPFTI 519
BLAST of slc24a-8 vs. Ensembl Celegans
Match: ncx-7 (Putative sodium/calcium exchanger 7 [Source:UniProtKB/Swiss-Prot;Acc:P34322]) HSP 1 Score: 56.6102 bits (135), Expect = 3.365e-8 Identity = 32/97 (32.99%), Postives = 58/97 (59.79%), Query Frame = 1
Query: 1060 KPGIWRKLFLVTFFI-SVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFI 1347
+P +++++ + FI S+ WI + + +V ++ ++G + ++GLT LA SI D IA V K GY MA++ +IG +F++L+ GLP+ I
Sbjct: 505 QPKYYKEIYSYSGFIMSIAWIYLISSEVVNVVTMLGVVSRVSHEVLGLTILAWSNSIGDLIADVSVVKQGYPRMAMAAAIGGPLFNLLMGFGLPFTI 601
BLAST of slc24a-8 vs. Ensembl Fly
Match: zyd (gene:FBgn0265767 transcript:FBtr0340198) HSP 1 Score: 306.22 bits (783), Expect = 6.980e-98 Identity = 185/496 (37.30%), Postives = 282/496 (56.85%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEA--LIMLF------MYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDS---------------------------SEEEEIMETGDVDSIHSRIRL-----DEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSF--LNPGSE-IPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
NCT +I++FP D + +R++G ++ H+ S+YLFVALA++CDEYFV ++E++C N+ +DVAGATFMAA +SAPEL +VIG FIT+ D+G+ TIVGSAVFN+L + A CGI G I L+WWP+ RD I Y +++ LI +++D ++WYEA L+ L+ MY + + Q + ++ G + + G S I++ +D + + DE G S + S + W+ + P+ + IPDC+K K+F +TF + ++WI +Y++ WMI +IGDTL IPD++MG+TFLAAGTS+P+A++ +VAK G+G M I NSIGSN FDIL+CLG+PW I+ F + PG + + S+ L ++ ITLLST+ +L T NK+KL++ +G L +Y++ + +SL ELN+ N P C R+
Sbjct: 5 NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFDKTFQKCAKELVENRICQNMANIQLNGGLNKEQAKATSTSGAGTTAISITTSTMTTTLSTTHSAGGGGGAVGLCSGPGAIVQMAPLDDAEAESHVAVAAADEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKN-NKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS 499
BLAST of slc24a-8 vs. Ensembl Fly
Match: CG12061 (gene:FBgn0040031 transcript:FBtr0332625) HSP 1 Score: 247.284 bits (630), Expect = 6.240e-76 Identity = 158/451 (35.03%), Postives = 253/451 (56.10%), Query Frame = 1
Query: 211 RKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQ-----RLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFEL 1548
R + +NCT +I EFPN +++ I+ VS+YLFV LAI+CD+Y V ++ERLC + +DVAGATF+AA +SAPEL + +G F+T D+G+ TIVGS+VFN+L I +CGIF L+WWP+ RD Y ++I +L +L D L+ WYEA +L +Y++ +VIQ R+ L + + L+ ++ T EEE ++ G D + ++ + + + F +W P + T+P R +F ++ +++WIS+ +Y+L W + ++G L+IPD IMGLT LAAGTS+P+ + Y+V+K GYG MAI N+IGSN FDIL+CLGLPW ++ L +I ++S++L TT L+ T VL ++ ++ + + +G++ + Y L + ++ E+
Sbjct: 29 RYDIDARNCTLPAIVEFPN---LMRQKSWIAIVVSTLVSMYLFVILAIVCDDYLVPAMERLCYTLRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQPT-KLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYIS-------------YVIQLSFDRRIQNLVRHEHAESELLDEDPMT--------REEEPLK-GFRDHVCAKPKTEYN----------------FYQWTWWAIKYPAELMLACTVPSA------RSIFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLK--ILIYQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLEI 429
BLAST of slc24a-8 vs. Ensembl Fly
Match: CG12061 (gene:FBgn0040031 transcript:FBtr0333740) HSP 1 Score: 196.823 bits (499), Expect = 1.282e-57 Identity = 131/389 (33.68%), Postives = 214/389 (55.01%), Query Frame = 1
Query: 397 EVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQ-----RLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFEL 1548
+ +DVAGATF+AA +SAPEL + +G F+T D+G+ TIVGS+VFN+L I +CGIF L+WWP+ RD Y ++I +L +L D L+ WYEA +L +Y++ +VIQ R+ L + + L+ ++ T EEE ++ G D + ++ + + + F +W P + T+P R +F ++ +++WIS+ +Y+L W + ++G L+IPD IMGLT LAAGTS+P+ + Y+V+K GYG MAI N+IGSN FDIL+CLGLPW ++ L +I ++S++L TT L+ T VL ++ ++ + + +G++ + Y L + ++ E+
Sbjct: 15 NALRMTYDVAGATFLAASTSAPELFVNFVGTFVTNGDIGLGTIVGSSVFNILVIAGVCGIFTQPT-KLDWWPVTRDTAWYLIAIASLTYVLWDSLVMWYEAFALLLLYIS-------------YVIQLSFDRRIQNLVRHEHAESELLDEDPMT--------REEEPLK-GFRDHVCAKPKTEYN----------------FYQWTWWAIKYPAELMLACTVPSARS------IFFLSMISAILWISLISYLLTWFLTILGYNLNIPDAIMGLTVLAAGTSVPEVASSYIVSKKGYGSMAICNAIGSNTFDILVCLGLPWLLK--ILIYQQKIDIDSTALTITTAMLVVTAAVLYLGLLARRFVMGKTVGYLSIIFYALFLIIACTLEI 356
BLAST of slc24a-8 vs. Ensembl Fly
Match: CG1090 (gene:FBgn0037238 transcript:FBtr0335201) HSP 1 Score: 194.897 bits (494), Expect = 1.583e-54 Identity = 101/196 (51.53%), Postives = 142/196 (72.45%), Query Frame = 1
Query: 1003 WVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
W + P+ +C T+PDCR+ +R + TF +S++WIS +Y +VWMI +IG TL IPDT+MGLTF+AAG S+PDA++ V K+G+GDMA+SN+IGSNVFDIL+CLGLPWFI+T+ + PGS + V S L ++T++L STVV L+ + +N WKL++ LG I + Y+ I L+SL+ELN+ G N P CP T
Sbjct: 438 WYVVYPIHFLCKKTMPDCRQEQ-YRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQTAIIKPGSHVNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVWYLFFITLASLYELNVFGYMNPPECPST 632 HSP 2 Score: 177.948 bits (450), Expect = 2.205e-48 Identity = 89/165 (53.94%), Postives = 124/165 (75.15%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
NCT +IE+FP M + R++GG+I HI V+++ F LAI+CDEYFV+SL+RLCE + DVAGATFMAAGSSAPEL T VIGVF K D+GIS ++GSAVFN++ +I++C + G+V LNWWP+ RDC YC+SI+ ++II+ + +I +E+++ML YV
Sbjct: 90 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTVCQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVG 254
BLAST of slc24a-8 vs. Ensembl Fly
Match: CG1090 (gene:FBgn0037238 transcript:FBtr0335203) HSP 1 Score: 194.897 bits (494), Expect = 1.583e-54 Identity = 101/196 (51.53%), Postives = 142/196 (72.45%), Query Frame = 1
Query: 1003 WVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
W + P+ +C T+PDCR+ +R + TF +S++WIS +Y +VWMI +IG TL IPDT+MGLTF+AAG S+PDA++ V K+G+GDMA+SN+IGSNVFDIL+CLGLPWFI+T+ + PGS + V S L ++T++L STVV L+ + +N WKL++ LG I + Y+ I L+SL+ELN+ G N P CP T
Sbjct: 438 WYVVYPIHFLCKKTMPDCRQEQ-YRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQTAIIKPGSHVNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVWYLFFITLASLYELNVFGYMNPPECPST 632 HSP 2 Score: 177.948 bits (450), Expect = 2.205e-48 Identity = 89/165 (53.94%), Postives = 124/165 (75.15%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
NCT +IE+FP M + R++GG+I HI V+++ F LAI+CDEYFV+SL+RLCE + DVAGATFMAAGSSAPEL T VIGVF K D+GIS ++GSAVFN++ +I++C + G+V LNWWP+ RDC YC+SI+ ++II+ + +I +E+++ML YV
Sbjct: 90 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTVCQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVG 254
BLAST of slc24a-8 vs. Ensembl Zebrafish
Match: slc24a5 (solute carrier family 24 member 5 [Source:ZFIN;Acc:ZDB-GENE-031210-1]) HSP 1 Score: 355.91 bits (912), Expect = 7.256e-117 Identity = 199/459 (43.36%), Postives = 298/459 (64.92%), Query Frame = 1
Query: 211 RKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRL--------PRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
R L C EFP F T +ERK+GGI+ + + Y+ ++++I+CDEYF+ SLE + E + DVAGATFMAAGSSAPEL T+ +GVF+TK D+G+STI+GSAV+N+LCI A CG+ +V L+ WP+FRDC+ Y +S+ A+I I++D + WY+ +L +Y Y+ +L ++ + +V+QR PR + GE+ PL+ + +S + S + + D H + L E ++F +P+ R+ WV LPV+ + + ++PDCR+P W+ +++TF +S +WIS TY+LVWM+ ++G+TL IPDT+MG+T LAAGTSIPD +A +VA++G DMA+SN +GSNVFD+L CLGLPWFI+T F++ GS + V SS L+F + TLL +++ L + +N WKL+ LG + LA Y+L LS L+EL I+GN
Sbjct: 50 RDLENASECVQPQSSEFPEGFFTVQERKDGGILIYFMIIFYMLLSVSIVCDEYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIMGSAVYNLLCICAACGLLSSAVGRLSCWPLFRDCVAYSISVAAVIAIISDNRVYWYDGACLLLVYGVYVAVLCFDLKISEYVMQRFSPCCWCLKPRDRDSGEQQ-PLVGWSDDSSLRVQRRSRNDSGIFQDDSGYSHLSLSLHGLNEISDEHKSVFSMPDHDLKRILWVLSLPVSTLLFVSVPDCRRP-FWKNFYMLTFLMSAVWISAFTYVLVWMVTIVGETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDML-CLGLPWFIQTVFVDVGSPVDVNSSGLVFMSCTLLLSIIFLFLAVHINGWKLDWKLGLVCLACYILFATLSILYELGIIGN 505
BLAST of slc24a-8 vs. Ensembl Zebrafish
Match: CABZ01081780.1 (sodium/potassium/calcium exchanger 2-like [Source:NCBI gene;Acc:571043]) HSP 1 Score: 264.618 bits (675), Expect = 5.689e-81 Identity = 177/486 (36.42%), Postives = 272/486 (55.97%), Query Frame = 1
Query: 238 TTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFV-----------------IQRL-------PRLKGYGEE---HNPLISQNL-PTSFGLLDSSEEEEIMETGDV-DSIHSRIRLDEDMTNLG--------ESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCP 1584
+ S ++P D + ++R+ G ++ H+F +Y+F+ALAI+CDE+FV +L + E I DVAGATFMAAG SAPEL TSVIGVFI+ S+VGI TIVGSAVFN+L +I +C +F +++L WWP+FRD Y + +I LI+ D +I + E++ +L Y AY++ + +NGN+ V + R+ PRL+ G HN L+ ++ LD E + E + I + ED + + P P S R ++ +LP+ + T+PD RKP +K F VTF ++ WI+ +Y++VW +G+T+ I + IMGLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FDI + L PW + S +N + V S+ L + L ++ ++ +I KW++++ LGFI LY++ + +S L E ++ CP
Sbjct: 85 SNESQGDYPTDLFSLEDRRRGAVLLHMFGMLYMFIALAIVCDEFFVPALTVITEKLTISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSKEILNLTWWPLFRDVSFYIIGLIMLIVFFLDNIITYCESISLLLAYAAYVLFMKFNGNVETLVKRMMNRNQVVEVEAQPKVNRMKHFENARPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLSEGKFREKASILHKIAKKKCQVEDSNGVAGAEEDEEDDQPLSLSWPESCQKRFTYLFILPIVFPLWITLPDVRKP-TSKKFFPVTFLGAICWIAGFSYLMVWWAHQVGETIGITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLL-FSMVNGMVPVQVSSNGLFCAIVLLFLMLLFVIVSIAACKWRMSKLLGFIMFLLYIVFLVVSVLLEDKVIA------CP 562
BLAST of slc24a-8 vs. Ensembl Zebrafish
Match: CABZ01081780.1 (sodium/potassium/calcium exchanger 2-like [Source:NCBI gene;Acc:571043]) HSP 1 Score: 264.233 bits (674), Expect = 7.381e-81 Identity = 177/486 (36.42%), Postives = 272/486 (55.97%), Query Frame = 1
Query: 238 TTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFV-----------------IQRL-------PRLKGYGEE---HNPLISQNL-PTSFGLLDSSEEEEIMETGDV-DSIHSRIRLDEDMTNLG--------ESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCP 1584
+ S ++P D + ++R+ G ++ H+F +Y+F+ALAI+CDE+FV +L + E I DVAGATFMAAG SAPEL TSVIGVFI+ S+VGI TIVGSAVFN+L +I +C +F +++L WWP+FRD Y + +I LI+ D +I + E++ +L Y AY++ + +NGN+ V + R+ PRL+ G HN L+ ++ LD E + E + I + ED + + P P S R ++ +LP+ + T+PD RKP +K F VTF ++ WI+ +Y++VW +G+T+ I + IMGLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FDI + L PW + S +N + V S+ L + L ++ ++ +I KW++++ LGFI LY++ + +S L E ++ CP
Sbjct: 94 SNESQGDYPTDLFSLEDRRRGAVLLHMFGMLYMFIALAIVCDEFFVPALTVITEKLTISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVFNILFVIGMCALFSKEILNLTWWPLFRDVSFYIIGLIMLIVFFLDNIITYCESISLLLAYAAYVLFMKFNGNVETLVKRMMNRNQVVEVEAQPKVNRMKHFENARPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLSEGKFREKASILHKIAKKKCQVEDSNGVAGAEEDEEDDQPLSLSWPESCQKRFTYLFILPIVFPLWITLPDVRKP-TSKKFFPVTFLGAICWIAGFSYLMVWWAHQVGETIGITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLL-FSMVNGMVPVQVSSNGLFCAIVLLFLMLLFVIVSIAACKWRMSKLLGFIMFLLYIVFLVVSVLLEDKVIA------CP 571
BLAST of slc24a-8 vs. Ensembl Zebrafish
Match: slc24a4b (solute carrier family 24 member 4b [Source:ZFIN;Acc:ZDB-GENE-081031-75]) HSP 1 Score: 198.364 bits (503), Expect = 1.363e-55 Identity = 99/164 (60.37%), Postives = 128/164 (78.05%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY 720
KNCT +I EFP+D T ERK+G ++ HI ++Y+F+ALAI+CD+YFV+SLE++CE N+ DVAGATFMAAGSSAPEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CGIF G V+ L WW +FRD Y LS++ALI+ + D I W+E+L+++ MY
Sbjct: 128 KNCTEPAIHEFPDDVFTNAERKSGAVLLHIIAALYMFLALAIVCDDYFVTSLEKICEKLNLSEDVAGATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLTWWAVFRDSFFYILSVVALIVFIYDEKIVWWESLVLVVMY 291 HSP 2 Score: 176.407 bits (446), Expect = 1.022e-47 Identity = 99/233 (42.49%), Postives = 147/233 (63.09%), Query Frame = 1
Query: 883 METGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
+E G+V S + ++T T F +P+ +R W+ P+ I +FTIP+C K W K F+++F +S +WI+V +Y +VWM+ +IG TL IPD IMG+TFLAAGTS+PD IA +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + + S L+++ + LL +V + + I +N WKL+ LG L LY + + S + E N+ N P C
Sbjct: 408 IENGNVPEDKSTEEKESELT------TPFRLPDGCMNRTKWLISWPLLLILFFTIPNCAKSR-WEKYFMLSFILSTVWIAVFSYFMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWALQTMAVNYGSVVMINSRGLLYSVVLLLGSVALTILGIHLNHWKLDFKLGVYVLLLYAVFLCFSIMIEYNVFTFVNLPMC 633
BLAST of slc24a-8 vs. Ensembl Zebrafish
Match: slc24a4a (solute carrier family 24 member 4a [Source:ZFIN;Acc:ZDB-GENE-050417-291]) HSP 1 Score: 192.2 bits (487), Expect = 1.529e-53 Identity = 101/202 (50.00%), Postives = 140/202 (69.31%), Query Frame = 1
Query: 145 GMYFFTKFKSNSDTMSELHGTGRKLLGL--------KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
G+ F ++SD + GR+L+ KNCT +I EFP D T ++R G ++ HIF ++Y+F+ALAI+CD+YFV+SLE++CE ++ DVAGATFMAAGSSAPEL S+IGVFIT DVG+ TIVGSAVFN+LCII +CGIF G V+ L + +FRD Y +S+IALI+ + D I W+E+L+++ MY+
Sbjct: 62 GLVMQEGFAASSDRL------GRRLMATVGDNETQEKNCTAPAIHEFPEDLFTNQQRSQGAVLLHIFAALYMFLALAIVCDDYFVTSLEKICEKLHLSEDVAGATFMAAGSSAPELFASIIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVFLTKYAVFRDSSYYIISVIALIVFIYDDEILWWESLVLIVMYLG 257 HSP 2 Score: 180.259 bits (456), Expect = 2.741e-49 Identity = 104/243 (42.80%), Postives = 154/243 (63.37%), Query Frame = 1
Query: 853 LLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
+L S ++ + ME G+V + +L E+ N SP F +P + + P++ + YFTIP+C K W F+++FF+S +WI+ +YILVWM+ ++G TL IPD IMG+TFLAAGTS+PD IA +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW I+T +N GS + + S L+++ + LL +V + V I VN+W+L+ LG L LY + + S + E N+ N P C
Sbjct: 363 VLVSDQKADTMENGNV----AEDKLSEEQEN-EISP--FRLPEGAMDTVKFFISWPISLLLYFTIPNCAKKR-WECCFMLSFFLSTVWIAAFSYILVWMVTIVGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGIQTMAVNYGSVVKINSRGLVYSVVLLLGSVALTVLGIHVNRWRLDLRLGIYVLVLYAIFLTFSIMIEYNVFTFVNLPMC 597
BLAST of slc24a-8 vs. Ensembl Xenopus
Match: SLC24A5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:100490024]) HSP 1 Score: 347.051 bits (889), Expect = 6.722e-114 Identity = 198/450 (44.00%), Postives = 289/450 (64.22%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP------RLKGYGE-EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP DF T +ERK GG+I H + +Y+F+A+AI+C+ YF+ SLE + E + DVAGATFMA GSSAPE T +GVF+TK D+G+STIVGSAV+N+L I A C + SV L WP+FRDC+ Y +S+ A+I I D I WYE+ ++ +Y YI+ + ++ + ++++R R G EH PL+ + + S + + + D I L + P++F +P + R+ WV LP+ + Y T+PDCR+ W+ LF++TF +S +WIS TYILVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A LVA++G GDMA+SN +GSNVFD+L CLG+PWFI+T F++ + + V SS + +TTI+LL +++ + I +N WKL++ LG + L +Y+L + LS L+EL I+GN
Sbjct: 8 CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWKEDSLPVIRRHSRSDSGIFQEESDYSQLSISLSGLKESSNNPPSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKR-WKNLFILTFLMSAVWISAVTYILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDML-CLGVPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVTLSILYELGIIGN 455
BLAST of slc24a-8 vs. Ensembl Xenopus
Match: SLC24A5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:100490024]) HSP 1 Score: 349.747 bits (896), Expect = 8.236e-114 Identity = 204/488 (41.80%), Postives = 301/488 (61.68%), Query Frame = 1
Query: 121 FFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP------RLKGYGE-EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
F F +V G + + S ++ R + C EFP DF T +ERK GG+I H + +Y+F+A+AI+C+ YF+ SLE + E + DVAGATFMA GSSAPE T +GVF+TK D+G+STIVGSAV+N+L I A C + SV L WP+FRDC+ Y +S+ A+I I D I WYE+ ++ +Y YI+ + ++ + ++++R R G EH PL+ + + S + + + D I L + P++F +P + R+ WV LP+ + Y T+PDCR+ W+ LF++TF +S +WIS TYILVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A LVA++G GDMA+SN +GSNVFD+L CLG+PWFI+T F++ + + V SS + +TTI+LL +++ + I +N WKL++ LG + L +Y+L + LS L+EL I+GN
Sbjct: 53 FALFLIVCGTVYLVNQVATSLVVTGTQRIRRDVENETLCIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWKEDSLPVIRRHSRSDSGIFQEESDYSQLSISLSGLKESSNNPPSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKR-WKNLFILTFLMSAVWISAVTYILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDML-CLGVPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVTLSILYELGIIGN 538
BLAST of slc24a-8 vs. Ensembl Xenopus
Match: SLC24A5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:100490024]) HSP 1 Score: 347.051 bits (889), Expect = 9.852e-114 Identity = 198/450 (44.00%), Postives = 289/450 (64.22%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP------RLKGYGE-EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP DF T +ERK GG+I H + +Y+F+A+AI+C+ YF+ SLE + E + DVAGATFMA GSSAPE T +GVF+TK D+G+STIVGSAV+N+L I A C + SV L WP+FRDC+ Y +S+ A+I I D I WYE+ ++ +Y YI+ + ++ + ++++R R G EH PL+ + + S + + + D I L + P++F +P + R+ WV LP+ + Y T+PDCR+ W+ LF++TF +S +WIS TYILVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A LVA++G GDMA+SN +GSNVFD+L CLG+PWFI+T F++ + + V SS + +TTI+LL +++ + I +N WKL++ LG + L +Y+L + LS L+EL I+GN
Sbjct: 20 CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWKEDSLPVIRRHSRSDSGIFQEESDYSQLSISLSGLKESSNNPPSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKR-WKNLFILTFLMSAVWISAVTYILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDML-CLGVPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVTLSILYELGIIGN 467
BLAST of slc24a-8 vs. Ensembl Xenopus
Match: SLC24A5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:100490024]) HSP 1 Score: 346.28 bits (887), Expect = 1.450e-113 Identity = 198/450 (44.00%), Postives = 289/450 (64.22%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP------RLKGYGE-EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP DF T +ERK GG+I H + +Y+F+A+AI+C+ YF+ SLE + E + DVAGATFMA GSSAPE T +GVF+TK D+G+STIVGSAV+N+L I A C + SV L WP+FRDC+ Y +S+ A+I I D I WYE+ ++ +Y YI+ + ++ + ++++R R G EH PL+ + + S + + + D I L + P++F +P + R+ WV LP+ + Y T+PDCR+ W+ LF++TF +S +WIS TYILVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A LVA++G GDMA+SN +GSNVFD+L CLG+PWFI+T F++ + + V SS + +TTI+LL +++ + I +N WKL++ LG + L +Y+L + LS L+EL I+GN
Sbjct: 14 CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWKEDSLPVIRRHSRSDSGIFQEESDYSQLSISLSGLKESSNNPPSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKR-WKNLFILTFLMSAVWISAVTYILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDML-CLGVPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVTLSILYELGIIGN 461
BLAST of slc24a-8 vs. Ensembl Xenopus
Match: SLC24A5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:100490024]) HSP 1 Score: 346.28 bits (887), Expect = 2.393e-113 Identity = 198/450 (44.00%), Postives = 289/450 (64.22%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP------RLKGYGE-EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP DF T +ERK GG+I H + +Y+F+A+AI+C+ YF+ SLE + E + DVAGATFMA GSSAPE T +GVF+TK D+G+STIVGSAV+N+L I A C + SV L WP+FRDC+ Y +S+ A+I I D I WYE+ ++ +Y YI+ + ++ + ++++R R G EH PL+ + + S + + + D I L + P++F +P + R+ WV LP+ + Y T+PDCR+ W+ LF++TF +S +WIS TYILVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A LVA++G GDMA+SN +GSNVFD+L CLG+PWFI+T F++ + + V SS + +TTI+LL +++ + I +N WKL++ LG + L +Y+L + LS L+EL I+GN
Sbjct: 31 CIASPSSEFPEDFFTEQERKQGGLIIHFLIILYMFLAVAIVCESYFIPSLEVISERLGLSQDVAGATFMAIGSSAPEFVTVFLGVFVTKGDIGVSTIVGSAVYNLLGICAACCLLSLSVSRLTCWPLFRDCVAYAISVAAVIAITFDNRIYWYESASLILIYGIYIVTMCFDIRINQYIMRRFSPCCTCCREAMVGNTEHEPLLGWKEDSLPVIRRHSRSDSGIFQEESDYSQLSISLSGLKESSNNPPSVFTMPENDLKRIIWVLSLPIITLLYLTVPDCRRKR-WKNLFILTFLMSAVWISAVTYILVWMVTVVGETLSIPDTVMGLTLLAAGTSIPDTVASVLVAREGKGDMAMSNIVGSNVFDML-CLGVPWFIKTVFVDRSAPVEVNSSGITYTTISLLFSILFIFVAIHLNGWKLDKKLGVMCLLMYLLFVTLSILYELGIIGN 478
BLAST of slc24a-8 vs. Ensembl Mouse
Match: Slc24a5 (solute carrier family 24, member 5 [Source:MGI Symbol;Acc:MGI:2677271]) HSP 1 Score: 333.183 bits (853), Expect = 3.963e-108 Identity = 202/459 (44.01%), Postives = 292/459 (63.62%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRL----PRLKGYGEEHNPLISQNLPTSFGLLDSSE----EEEIMETG--DVDSIHSRIRLD-EDMTNLGESP-TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNR 1572
C EFP F T++E +GGI+ + + +Y+ +A++I+CD+YF+ SLE + + + DVAGATFMAAGSSAPEL T+ +GVFITK D+GISTI+GSA++N+L I A CG+ V L+ WP+FRDC +Y +S+ A+ I+ D I WYE +L +Y Y+++L ++ + V++ P L EE I Q T G D S+ + ++G DS +S++ L ++ + E P ++F +P + R++WV LP+ + T PDCR+ W+ F++TFF+S +WIS TYILVWM+ + G+TL IPDT+MGLT LAAGTSIPD + LVA+ G GDMAISN +GSNVFD+L CLGLPWFI+T+F N + I V S L + TI+L +++ L + N WKL+R LG + L LY+ + LS L+E+ I+GN NR
Sbjct: 45 QCAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARAMEER---IEQQ--TLLGWEDESQLFIRRQSRTDSGIFQEDSGYSQLSLSLHGLSQVSEDPPSVFSMPEADLRRIFWVLSLPIITLLALTTPDCRRK-FWKNYFVITFFMSALWISAFTYILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDML-CLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNISILFLFLAVHFNGWKLDRKLGVVCLVLYLGLATLSVLYEIGIIGN-NR 495
BLAST of slc24a-8 vs. Ensembl Mouse
Match: Slc24a4 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 [Source:MGI Symbol;Acc:MGI:2447362]) HSP 1 Score: 189.119 bits (479), Expect = 1.142e-52 Identity = 97/183 (53.01%), Postives = 130/183 (71.04%), Query Frame = 1
Query: 175 NSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
N M+ ++GT KNCT +I EFP D + KER++G ++ HI ++Y+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSS PEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CG+F G V+ L WW + RD + Y LS+I LI + D I W+E L+++ +YV
Sbjct: 61 NRKLMAPINGTPLA----KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYV 239 HSP 2 Score: 150.214 bits (378), Expect = 9.254e-39 Identity = 70/141 (49.65%), Postives = 100/141 (70.92%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVE 1389
F +P + + WV P+ + TIP+C KP W K F+VTF + +WI+V +Y++VW++ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + +
Sbjct: 396 FSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPR-WEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKIN 535
BLAST of slc24a-8 vs. Ensembl Mouse
Match: Slc24a4 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 [Source:MGI Symbol;Acc:MGI:2447362]) HSP 1 Score: 189.504 bits (480), Expect = 1.790e-52 Identity = 97/183 (53.01%), Postives = 130/183 (71.04%), Query Frame = 1
Query: 175 NSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
N M+ ++GT KNCT +I EFP D + KER++G ++ HI ++Y+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSS PEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CG+F G V+ L WW + RD + Y LS+I LI + D I W+E L+++ +YV
Sbjct: 44 NRKLMAPINGTPLA----KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYV 222 HSP 2 Score: 174.866 bits (442), Expect = 3.548e-47 Identity = 93/205 (45.37%), Postives = 136/205 (66.34%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F +P + + WV P+ + TIP+C KP W K F+VTF + +WI+V +Y++VW++ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + + S L+++ + LL +V + V I +NKW+L+R LG L LY + + S + E N+ N P C
Sbjct: 398 FSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPR-WEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMC 601
BLAST of slc24a-8 vs. Ensembl Mouse
Match: Slc24a4 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 [Source:MGI Symbol;Acc:MGI:2447362]) HSP 1 Score: 189.504 bits (480), Expect = 2.139e-52 Identity = 97/183 (53.01%), Postives = 130/183 (71.04%), Query Frame = 1
Query: 175 NSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
N M+ ++GT KNCT +I EFP D + KER++G ++ HI ++Y+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSS PEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CG+F G V+ L WW + RD + Y LS+I LI + D I W+E L+++ +YV
Sbjct: 61 NRKLMAPINGTPLA----KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYV 239 HSP 2 Score: 175.252 bits (443), Expect = 3.227e-47 Identity = 93/205 (45.37%), Postives = 136/205 (66.34%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F +P + + WV P+ + TIP+C KP W K F+VTF + +WI+V +Y++VW++ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + + S L+++ + LL +V + V I +NKW+L+R LG L LY + + S + E N+ N P C
Sbjct: 415 FSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPR-WEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMC 618
BLAST of slc24a-8 vs. Ensembl Mouse
Match: Slc24a4 (solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 [Source:MGI Symbol;Acc:MGI:2447362]) HSP 1 Score: 188.734 bits (478), Expect = 2.422e-52 Identity = 97/183 (53.01%), Postives = 130/183 (71.04%), Query Frame = 1
Query: 175 NSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
N M+ ++GT KNCT +I EFP D + KER++G ++ HI ++Y+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSS PEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CG+F G V+ L WW + RD + Y LS+I LI + D I W+E L+++ +YV
Sbjct: 61 NRKLMAPINGTPLA----KNCTDPAIHEFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICEKLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVRLTWWAVCRDSVYYTLSVIVLIAFIYDEEIVWWEGLVLIILYV 239 HSP 2 Score: 174.866 bits (442), Expect = 2.886e-47 Identity = 93/205 (45.37%), Postives = 136/205 (66.34%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F +P + + WV P+ + TIP+C KP W K F+VTF + +WI+V +Y++VW++ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW ++T +N GS + + S L+++ + LL +V + V I +NKW+L+R LG L LY + + S + E N+ N P C
Sbjct: 396 FSMPEAKGDKAKWVFTWPLIFLLCVTIPNCSKPR-WEKFFMVTFITATLWIAVFSYLMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGIPWGLQTMVINYGSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGIYVLVLYAVFLCFSIMIEFNVFTFVNLPMC 599
BLAST of slc24a-8 vs. UniProt/SwissProt
Match: sp|Q49SH1|NCKX5_DANRE (Sodium/potassium/calcium exchanger 5 OS=Danio rerio OX=7955 GN=slc24a5 PE=2 SV=1) HSP 1 Score: 355.91 bits (912), Expect = 4.865e-116 Identity = 199/459 (43.36%), Postives = 298/459 (64.92%), Query Frame = 1
Query: 211 RKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRL--------PRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
R L C EFP F T +ERK+GGI+ + + Y+ ++++I+CDEYF+ SLE + E + DVAGATFMAAGSSAPEL T+ +GVF+TK D+G+STI+GSAV+N+LCI A CG+ +V L+ WP+FRDC+ Y +S+ A+I I++D + WY+ +L +Y Y+ +L ++ + +V+QR PR + GE+ PL+ + +S + S + + D H + L E ++F +P+ R+ WV LPV+ + + ++PDCR+P W+ +++TF +S +WIS TY+LVWM+ ++G+TL IPDT+MG+T LAAGTSIPD +A +VA++G DMA+SN +GSNVFD+L CLGLPWFI+T F++ GS + V SS L+F + TLL +++ L + +N WKL+ LG + LA Y+L LS L+EL I+GN
Sbjct: 50 RDLENASECVQPQSSEFPEGFFTVQERKDGGILIYFMIIFYMLLSVSIVCDEYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIMGSAVYNLLCICAACGLLSSAVGRLSCWPLFRDCVAYAISVAAVIAIISDNRVYWYDGACLLLVYGVYVAVLCFDLRISEYVMQRFSPCCWCLKPRDRDSGEQQ-PLVGWSDDSSLRVQRRSRNDSGIFQDDSGYSHLSLSLHGLNEISDEHKSVFSMPDHDLKRILWVLSLPVSTLLFVSVPDCRRP-FWKNFYMLTFLMSAVWISAFTYVLVWMVTIVGETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDML-CLGLPWFIQTVFVDVGSPVEVNSSGLVFMSCTLLLSIIFLFLAVHINGWKLDWKLGLVCLACYILFATLSILYELGIIGN 505
BLAST of slc24a-8 vs. UniProt/SwissProt
Match: sp|Q71RS6|NCKX5_HUMAN (Sodium/potassium/calcium exchanger 5 OS=Homo sapiens OX=9606 GN=SLC24A5 PE=1 SV=1) HSP 1 Score: 353.599 bits (906), Expect = 3.326e-115 Identity = 201/460 (43.70%), Postives = 292/460 (63.48%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQR-----------LPR-----LKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C EFP F TR+ER++GGII + + +Y+F+A++I+CDEYF+ SLE + E + DVAG TFMAAGSSAPEL T+ +GVFITK D+GISTI+GSA++N+L I A CG+ +V L+ WP+FRDC Y +S A++ I+ D + WYE ++L +Y Y+++L ++ + ++I++ + R L G+ +E P I + T G+ + S+H ++ ED P++F +P + R++WV LP+ + + T PDCRK W+ F++TFF+S IWIS TYILVWM+ + G+TL+IPDT+MGLT LAAGTSIPD IA LVA+ G GDMA+SN +GSNVFD+L CLG+PWFI+T+F+N + V S L + TI+L +++ L + N WKL+R LG + L Y+ + LS L+EL I+GN
Sbjct: 45 QCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFMAISIVCDEYFLPSLEIISESLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGALLLLIYGLYVLVLCFDIKINQYIIKKCSPCCACLAKAMERSEQQPLMGWEDEGQPFIRRQSRTDSGIFYEDSGYSQLSI----SLHGLSQVSED------PPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKK-FWKNYFVITFFMSAIWISAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNVFDML-CLGIPWFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKLGIVCLLSYLGLATLSVLYELGIIGN 492
BLAST of slc24a-8 vs. UniProt/SwissProt
Match: sp|Q8C261|NCKX5_MOUSE (Sodium/potassium/calcium exchanger 5 OS=Mus musculus OX=10090 GN=Slc24a5 PE=2 SV=1) HSP 1 Score: 333.183 bits (853), Expect = 2.772e-107 Identity = 202/459 (44.01%), Postives = 292/459 (63.62%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRL----PRLKGYGEEHNPLISQNLPTSFGLLDSSE----EEEIMETG--DVDSIHSRIRLD-EDMTNLGESP-TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNR 1572
C EFP F T++E +GGI+ + + +Y+ +A++I+CD+YF+ SLE + + + DVAGATFMAAGSSAPEL T+ +GVFITK D+GISTI+GSA++N+L I A CG+ V L+ WP+FRDC +Y +S+ A+ I+ D I WYE +L +Y Y+++L ++ + V++ P L EE I Q T G D S+ + ++G DS +S++ L ++ + E P ++F +P + R++WV LP+ + T PDCR+ W+ F++TFF+S +WIS TYILVWM+ + G+TL IPDT+MGLT LAAGTSIPD + LVA+ G GDMAISN +GSNVFD+L CLGLPWFI+T+F N + I V S L + TI+L +++ L + N WKL+R LG + L LY+ + LS L+E+ I+GN NR
Sbjct: 45 QCAVSPASEFPEGFFTKQESTDGGIVIYFLIILYMCMAISIVCDKYFLPSLEIISDSLGLSQDVAGATFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAACGLLSNMVSTLSCWPLFRDCAVYAVSVGAVFGIIFDNRIYWYEGAGLLLIYGLYVLLLCFDTTISRHVMKTCSPCCPCLARAMEER---IEQQ--TLLGWEDESQLFIRRQSRTDSGIFQEDSGYSQLSLSLHGLSQVSEDPPSVFSMPEADLRRIFWVLSLPIITLLALTTPDCRRK-FWKNYFVITFFMSALWISAFTYILVWMVTVTGETLGIPDTVMGLTLLAAGTSIPDTVTSVLVARKGKGDMAISNIVGSNVFDML-CLGLPWFIKTAFTNASAPIEVNSKGLTYITISLNISILFLFLAVHFNGWKLDRKLGVVCLVLYLGLATLSVLYEIGIIGN-NR 495
BLAST of slc24a-8 vs. UniProt/SwissProt
Match: sp|Q9VN12|NCKXH_DROME (Probable sodium/potassium/calcium exchanger CG1090 OS=Drosophila melanogaster OX=7227 GN=CG1090 PE=2 SV=4) HSP 1 Score: 194.897 bits (494), Expect = 1.587e-53 Identity = 101/196 (51.53%), Postives = 142/196 (72.45%), Query Frame = 1
Query: 1003 WVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
W + P+ +C T+PDCR+ +R + TF +S++WIS +Y +VWMI +IG TL IPDT+MGLTF+AAG S+PDA++ V K+G+GDMA+SN+IGSNVFDIL+CLGLPWFI+T+ + PGS + V S L ++T++L STVV L+ + +N WKL++ LG I + Y+ I L+SL+ELN+ G N P CP T
Sbjct: 438 WYVVYPIHFLCKKTMPDCRQEQ-YRNWYPFTFLMSMVWISFYSYFMVWMITVIGSTLAIPDTVMGLTFVAAGVSVPDALSSIAVIKEGFGDMAVSNAIGSNVFDILVCLGLPWFIQTAIIKPGSHVNVISKGLAYSTLSLFSTVVFLILSTHLNGWKLDKRLGIILMVWYLFFITLASLYELNVFGYMNPPECPST 632 HSP 2 Score: 177.948 bits (450), Expect = 2.211e-47 Identity = 89/165 (53.94%), Postives = 124/165 (75.15%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
NCT +IE+FP M + R++GG+I HI V+++ F LAI+CDEYFV+SL+RLCE + DVAGATFMAAGSSAPEL T VIGVF K D+GIS ++GSAVFN++ +I++C + G+V LNWWP+ RDC YC+SI+ ++II+ + +I +E+++ML YV
Sbjct: 90 NCTPPAIEQFPQPLMNKWARQHGGLILHILVAVFTFFGLAIVCDEYFVASLDRLCEELKLSPDVAGATFMAAGSSAPELATVVIGVFFAKDDIGISGVIGSAVFNIMFVISVCALCSGTVCQLNWWPLVRDCFFYCVSILVMLIIIFNDVISCFESVVMLLCYVG 254
BLAST of slc24a-8 vs. UniProt/SwissProt
Match: sp|Q9HC58|NCKX3_HUMAN (Sodium/potassium/calcium exchanger 3 OS=Homo sapiens OX=9606 GN=SLC24A3 PE=2 SV=4) HSP 1 Score: 191.045 bits (484), Expect = 5.035e-52 Identity = 95/165 (57.58%), Postives = 129/165 (78.18%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
KNCT ++ EFPND T ++R+ G ++ H+ +IY+F ALAI+CD++FV SLE++CE ++ DVAGATFMAAGSSAPEL TSVIGVFITK DVG+ TIVGSAVFN+LCII +CG+F G V+ L+ W + RD I Y LS+IALI+ + D + W+E+L+++ MY+
Sbjct: 85 KNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYL 249 HSP 2 Score: 173.711 bits (439), Expect = 9.982e-46 Identity = 98/207 (47.34%), Postives = 138/207 (66.67%), Query Frame = 1
Query: 961 TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
T F+ P+ + W P++ + YFT+P+C KP W K F+VTF S +WI+ +Y++VWM+ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSNVFDILI LGLPW ++T ++ GS I + S LI++ LL++V V V + +NKW+L++ LG L LY + + S + E N+ N P C
Sbjct: 436 TPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPR-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMC 641
BLAST of slc24a-8 vs. TrEMBL
Match: A0A0H3YKA3 (Slc24a-8 OS=Schmidtea mediterranea OX=79327 GN=slc24a-8 PE=2 SV=1) HSP 1 Score: 910.598 bits (2352), Expect = 0.000e+0 Identity = 505/505 (100.00%), Postives = 505/505 (100.00%), Query Frame = 1
Query: 82 MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS 1596
MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEALIMLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS
Sbjct: 1 MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEALIMLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS 505
BLAST of slc24a-8 vs. TrEMBL
Match: A0A0H3YJ53 (Slc24a-6 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc24a-6 PE=2 SV=1) HSP 1 Score: 513.072 bits (1320), Expect = 3.798e-175 Identity = 277/507 (54.64%), Postives = 367/507 (72.39%), Query Frame = 1
Query: 91 KNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP-RLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDS---IHSRIR--LDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTS 1593
K H + KI+ YFSL+ G F K + G RKLL L NCT RS+EEFP+DFMTR ++KNGG++FHI +S YLF+A+AI+CD+YFVSSLER+CEV +++HDVAGATFMA G SAPELCT+VI VFIT SDVG+STI+GSA+FNVLC+ AICGIF G VI L WWP+FRDC+IYC++II L I+LND + WYE LIML +Y YI++LY N ++Y V++ LP + E PL +N + L+D SE ++ +E D++S + RI +ED + ++F +P+SF RL+WV MLPV +C+ TIPDCR+PGI++KLF +TF +S++WI++ Y+LVWMIC+ GD L IPDT+MGLT LAAG SIPDAI+ +LV K+G+GDMA+ SIGSN D+L+ LGLPW ++T ++PGS I + SS L +T++TLLSTV +LV I +NKW+LNR LG IF LY ++ S L+ELN+ G F PPCPRT
Sbjct: 1 KKHKNFLKIILCYFSLIFGSIFLLKVNDIGGKDANFDGKSRKLLSLSNCTKRSVEEFPDDFMTRVDKKNGGVLFHIVMSAYLFMAIAIVCDDYFVSSLERICEVLHMRHDVAGATFMALGGSAPELCTAVIAVFITDSDVGVSTIIGSALFNVLCVTAICGIFAGKVIQLTWWPVFRDCMIYCITIITLTIVLNDEQVHWYEGLIMLIIYSLYILLLYKNDSVYQIVVKLLPISKRKLDPEKKPLFYENDSLAKILID-SENDDDLEKEDLNSNFQTNKRIHGCDNEDSIEGDKLESMFAIPDSFVSRLHWVTMLPVTVLCFLTIPDCRRPGIYKKLFFLTFLMSLVWITICIYLLVWMICITGDALGIPDTVMGLTLLAAGASIPDAISSFLVMKEGHGDMALCTSIGSNTLDVLVGLGLPWLLKTGMIHPGSTIQISSSGLTYTSLTLLSTVFILVICIFINKWRLNRLLGSIFFLLYSTVVIFSCLYELNVFGQFALPPCPRTK 506
BLAST of slc24a-8 vs. TrEMBL
Match: A0A210QG44 (Sodium/potassium/calcium exchanger 5 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT19355 PE=3 SV=1) HSP 1 Score: 414.075 bits (1063), Expect = 1.051e-135 Identity = 224/466 (48.07%), Postives = 323/466 (69.31%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKG----YGEEHNPLISQNLPTSFGLLDSSE----EEEIMETGDVDSIHSRIRLDEDMT----NLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKP-GIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
+C RS+EEFP +FM+ ++ ++GG + HI +Y+F A+AI+CD+YFV+SLE +C+ + DVAGATFMAAGSSAPELCTS+IGVFI +SDVG+ TIVGSAVFN+L II +C IF G V+ L WWPMFRDC+ Y S+IAL+++++D + WYE LI+ MY+ YI+++Y+N ++ F + K Y ++N Q L + +LDS + +E+ D ++ + + T + ESP + +P++ R +W+AMLP+ + Y T+PDCRKP G WRKL+ +TF +S++W+ +Y++VWM+ + GD L+IPDT+MGLT LAAGTS+PD +A VA+DGYGDMAISNSIGSNVFD+L+CLG+PW IR++ ++ G I + S L ++ +TLLSTV + +++ KWKL R G + L Y+++IALS L+ELN+ G FN P CPRT
Sbjct: 84 SCIPRSVEEFPGNFMSLEDTQDGGFLIHILFVVYIFGAIAIVCDDYFVASLEIICDELQLSEDVAGATFMAAGSSAPELCTSLIGVFIAESDVGVGTIVGSAVFNILFIIGVCAIFAGMVVELTWWPMFRDCLFYLFSVIALVVVIHDNRVHWYEGLILFLMYLVYILVMYFNKTIHAFAERIRADFKSGNLTYDADNN---RQGLLEAQKVLDSEKSTGNDEKARNQTDAETTFTNSNTESSQTVAEEDKYESPWV--IPDTLVARSFWIAMLPMKVLFYVTVPDCRKPWGHWRKLYPLTFMMSIVWLVGLSYVMVWMVAIAGDALEIPDTVMGLTLLAAGTSVPDCLASLFVARDGYGDMAISNSIGSNVFDVLVCLGIPWLIRSAAIDDGEPIMITSDGLTYSALTLLSTVFFIGIAVILAKWKLGRTFGVVCLIAYVVVIALSCLYELNVFGTFNSPTCPRT 544
BLAST of slc24a-8 vs. TrEMBL
Match: A0A1I8HC93 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 410.609 bits (1054), Expect = 2.287e-134 Identity = 235/458 (51.31%), Postives = 313/458 (68.34%), Query Frame = 1
Query: 223 GLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMET---GDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPR 1587
G CT RS+E FP D T ++++ G II H+ V+++LF ALA++CD+YFVSSLE +C+V ++K DVAGATFMAAGSSAPEL TS+IGVF KSDVGISTIVGSAVFN+L I+++CG+F I+L+WWP+FRDC YCLS++ALI+++ +G + WYE++I + MY YI+I+YYN + + R P L + D E I+ + G + +S++R E ESP +P R+YWV MLP + FTIPDCR+PG WRK F +TF SV+WI+ +Y+LVWM+C +GDTL IPDT+MGLT LAAGTS+PDA+A VA+DG+GDMA+SNSIGSNVFDIL+ LG+PWFI T PGS + V S+ L ++TI LLSTVV L + +NK +L+R LG L +Y++ I S L+E N+ G N PPCPR
Sbjct: 92 GKNACTPRSVETFPPDLFTLEQKRQGAIIIHVLVAVWLFAALAVVCDDYFVSSLEVICDVLDLKSDVAGATFMAAGSSAPELFTSIIGVFFAKSDVGISTIVGSAVFNILFIVSLCGVFATQAIYLSWWPIFRDCGYYCLSVVALIVVIQNGFVDWYESVIFVVMYALYIVIMYYNEAIDRNISDRYPSLGTGASAAAAAGGARRLDESNMDD--ERVAIVPSSGEGGGTTTYSQLRGGEGNVEEFESP--LTMPQGLVKRIYWVVMLPWTCVFLFTIPDCRRPGRWRKFFFITFINSVLWIAGMSYLLVWMVCAVGDTLGIPDTVMGLTILAAGTSVPDAMASVFVARDGFGDMAVSNSIGSNVFDILVGLGVPWFIDTIIREPGSTVVVNSNGLTYSTIMLLSTVVFLFVAVYLNKMRLDRKLGAACLVVYIVFITFSILYETNVFGEMNPPPCPR 545
BLAST of slc24a-8 vs. TrEMBL
Match: A0A1S3H8R1 (sodium/potassium/calcium exchanger 3 OS=Lingula unguis OX=7574 GN=LOC106153130 PE=3 SV=1) HSP 1 Score: 407.142 bits (1045), Expect = 2.861e-133 Identity = 231/467 (49.46%), Postives = 321/467 (68.74%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIF-HIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPR-----------LKGY-GEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
+NCT RS+EEFP D T ++++ G+IF H ++Y+F ALAI+CD+YFV SLE +C + DVAGATFMAAGSSAPEL TS+IGVFI +SDVG+ TIVGSAVFN+L I+A+C +F G VI L WWP+FRDC Y LS+I L +++ DG + WYEALIM MY+ Y+ +Y+N + + I ++ LKG+ GEE PL+ ++ S S E E G+ + S DED ESP + VP SF R YWVAMLPV+A+ + T+PD R+ G+W++LFL++F +SV+WIS +Y++VWM+ ++GDT +IPD +MGLT LAAGTS+PDA++ VA+DG+GDMAISNS+GSN+FDIL+CLGLPW I G+ + + S +++FT+I+LL+TV+ L+ + VN WKLN+ G I L +Y++ + S ++ELN+ G N P CPR
Sbjct: 76 QNCTKRSVEEFPPDLFTLEQKQRYGLIFLHCLGALYMFSALAIVCDDYFVPSLEHICTRLGLSPDVAGATFMAAGSSAPELATSIIGVFIAQSDVGLGTIVGSAVFNILIIVAMCSLFAGMVIPLTWWPLFRDCSYYALSVIVLTVVIQDGEVHWYEALIMFTMYILYVTFMYFNPRVSSWAIAKVHEFQHRRGHFPGNLKGHAGEESAPLLGEDAEKSSVSFKSGETETHF-GGENSATESED--DEDF----ESP--WTVPESFLKRFYWVAMLPVSALLFLTVPDSRRGGVWKRLFLLSFIMSVVWISGFSYVMVWMVAIMGDTWNIPDAVMGLTILAAGTSVPDAMSSLFVARDGFGDMAISNSVGSNIFDILLCLGLPWMIEC--FRVGAPVDINSKTIVFTSISLLATVIFLLVAVAVNGWKLNKKFGIICLFVYVVFMLFSCMYELNVFGEINFPSCPRN 531
BLAST of slc24a-8 vs. Ensembl Cavefish
Match: slc24a5 (solute carrier family 24 member 5 [Source:ZFIN;Acc:ZDB-GENE-031210-1]) HSP 1 Score: 291.582 bits (745), Expect = 1.794e-93 Identity = 182/417 (43.65%), Postives = 258/417 (61.87%), Query Frame = 1
Query: 334 LFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQR-------LPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
+ +A++IICD+YF+ SLE + E + DVAGATFMAAGSSAPEL T+ +GVF+TK D+G+STIVGSAV+N+L I A CGI V L WP+FRDC + N L+Q Y+A +L +Y YI++L ++ + ++++R L + E PL+ N +S + S + + D H + L + E+P + V LPV + Y TIPDCR+ WRK +++TFF+S +WIS TY+LVWM+ +IG+TL IPDT+MGLT LAAGTSIPD +A +VA++G DMA+SN +GSNVFD+L CLGLPWFI+T+F++ + V S+ ++F T TLL ++V L + +N WKL+ LG + L Y+L LS L+EL I+GN
Sbjct: 1 MLLAVSIICDDYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGILTAVVGRLTCWPLFRDC----------VAYANQLLLQQYDAACLLLVYGVYIVVLCFDLRISEYMMRRFSPCCVCLSKSVNERSEQQPLMGWNNESSLRVPRRSRTDSGIFHDDSGYSHLSLSLHG----------LHEIPEADPG----VLSLPVIVLLYLTIPDCRRR-YWRKCYMLTFFMSAVWISAFTYVLVWMVTIIGETLAIPDTVMGLTLLAAGTSIPDTVASVMVAREGKADMAMSNIVGSNVFDML-CLGLPWFIKTAFVDTTGPVVVNSTGMVFITSTLLLSIVFLFLAVHINGWKLDWKLGIVCLLCYILFATLSILYELGIIGN 391
BLAST of slc24a-8 vs. Ensembl Cavefish
Match: SLC24A2 (solute carrier family 24 member 2 [Source:NCBI gene;Acc:103026719]) HSP 1 Score: 257.299 bits (656), Expect = 4.462e-78 Identity = 176/496 (35.48%), Postives = 268/496 (54.03%), Query Frame = 1
Query: 238 TTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFV---IQR-------------LPRLKGYGEE---HNPLISQNL---------PTSFGL----------------------------LDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNIL 1557
S ++P D + ++R+ G ++ H+ +Y+F+ALAI+CDE+FV +L + E I DVAGATFMAAG SAPEL TSVIGVFI+ S+VGI TIVGSAVFN+L +I +C +F +++L WWP+FRD Y L +I LI+ D I ++E++ +L Y Y+I + YNG + F+ I R PRL+ G HN L+ ++ P S G L +S E+ T ++ + + + P P + R ++ +LP+ + T+PD RKP +K F +TF ++ WI+ +Y++VW +G+T+ I + IMGLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FDI + L PW + S +N I V S+ L + L ++ ++ +I KWK+++ LGFI LY++ + +S + E I+
Sbjct: 85 ANESQGDYPEDLFSLEQRRRGAVVLHMIGMLYMFIALAIVCDEFFVPALTVITEKLAISDDVAGATFMAAGGSAPELFTSVIGVFISHSNVGIGTIVGSAVFNILFVIGMCAVFSKEILNLTWWPLFRDVSFYILGLIMLIVFFLDNYISYWESIALLTAYACYVIFMKYNGQVEMFIKGLINRNQVVEVVEAPPKAKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLSEGKFREKASILHKIAKKKCQVEDANGVADKNLPNSSNVEVEVTPPLNGTAGQEGDTGEEDEEDDQPLSLSWPETCRKRFTYLFILPIVFPLWITLPDVRKP-TSKKFFPITFLGAICWIAAFSYLMVWWAHQVGETIGITEEIMGLTMLAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPFPWLLY-SLINGLKPIVVSSNGLFCAIVLLFLMLLFVIISIAACKWKMSKLLGFIMFLLYLVFLVVSVMLEDKII 578
BLAST of slc24a-8 vs. Ensembl Cavefish
Match: slc24a4b (sodium/potassium/calcium exchanger 4 [Source:NCBI gene;Acc:103043044]) HSP 1 Score: 201.06 bits (510), Expect = 8.174e-57 Identity = 102/181 (56.35%), Postives = 133/181 (73.48%), Query Frame = 1
Query: 208 GRKLLG--------LKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
GRKL+ KNCT +I EFP+D+ T ERK+G ++ HI ++Y+F+ALAI+CD+YFV+SLE+LCE ++ DVAGATFMAAGSSAPEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CGIF G V+ L WW +FRD + Y S++ALI + D I W+E+L+++ MY
Sbjct: 63 GRKLMASAADNDTERKNCTEPAIREFPDDYFTNAERKSGAVLLHILAALYMFLALAIVCDDYFVTSLEKLCEKLDLSEDVAGATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLTWWAVFRDSLYYTFSVVALIAFIYDEKIVWWESLVLVVMYAG 243 HSP 2 Score: 181.8 bits (460), Expect = 7.816e-50 Identity = 96/211 (45.50%), Postives = 140/211 (66.35%), Query Frame = 1
Query: 949 GESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
GE + F +P ++ W+ P+ + +FTIP+C KP W K F+++F +S +WI++ +Y +VWM+ +IG TL IPD IMG+TFLAAGTS+PD IA +VA+ G GDMA+SN+IGSNVFDIL+ LGLPW ++T +N GSE+ + S L+++ + LL +V + + I VN WKL+ LG L LY + + S + E N+ N P C
Sbjct: 393 GELTSPFRLPRGCMNKTKWLISWPLLLLLFFTIPNCAKPR-WEKYFMLSFLLSTVWIAIFSYFMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGLPWALQTMAINYGSEVMINSRGLVYSVVLLLGSVALTILGIHVNHWKLDFKLGMYVLVLYAIFLCFSIMIEYNVFTFVNLPMC 602
BLAST of slc24a-8 vs. Ensembl Cavefish
Match: slc24a3 (solute carrier family 24 member 3 [Source:NCBI gene;Acc:103023188]) HSP 1 Score: 191.045 bits (484), Expect = 4.381e-53 Identity = 91/165 (55.15%), Postives = 124/165 (75.15%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYV 723
KNCT + EFP+D T++ER G + H+F ++Y+F ALA++CD+YFV SLE++CE ++ DVAGATFMAAGSSAPEL TSVIGVFITK DVG+ TIVGSAVFN+LCII +CGIF G + L+ W + RD Y +S+ LI+ + D + W+E+L+++ MY+
Sbjct: 77 KNCTPPGVHEFPDDIFTKQERMEGAVALHVFCAMYMFYALALVCDDYFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGIFAGQAVRLSCWTLMRDSTYYTISVTTLIVFIYDEKVTWWESLVLILMYL 241 HSP 2 Score: 169.859 bits (429), Expect = 1.981e-45 Identity = 93/205 (45.37%), Postives = 135/205 (65.85%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F P C++ W+ P++ + +FT+P+C P W + F+ TF S +WI+ +YI+VWM+ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSNVFDIL+ LGLPW ++T ++ GS I + S LI + LL++V + V + +NKW L++ LG + L +Y + + S L E N+ N P C
Sbjct: 430 FRCPGGVCNKFKWLLAWPLSLLLFFTVPNCNSPR-WERWFMFTFISSTLWIAGFSYIMVWMVTVIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNSIGSNVFDILVGLGLPWALQTLAIDYGSVIHLNSRGLIISVGLLLASVFLTVLGVHLNKWTLDKRLGILCLLMYAVFLCFSILIEFNVFIFVNLPTC 633
BLAST of slc24a-8 vs. Ensembl Cavefish
Match: slc24a4b (sodium/potassium/calcium exchanger 4 [Source:NCBI gene;Acc:103043044]) HSP 1 Score: 184.111 bits (466), Expect = 2.762e-51 Identity = 82/126 (65.08%), Postives = 103/126 (81.75%), Query Frame = 1
Query: 247 SIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRD 624
+I EFP+D+ T ERK+G ++ HI ++Y+F+ALAI+CD+YFV+SLE+LCE ++ DVAGATFMAAGSSAPEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CGIF G V+ L WW +FRD
Sbjct: 16 AIREFPDDYFTNAERKSGAVLLHILAALYMFLALAIVCDDYFVTSLEKLCEKLDLSEDVAGATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVLLTWWAVFRD 141 HSP 2 Score: 174.096 bits (440), Expect = 1.099e-47 Identity = 92/197 (46.70%), Postives = 134/197 (68.02%), Query Frame = 1
Query: 991 HRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
++ W+ P+ + +FTIP+C KP W K F+++F +S +WI++ +Y +VWM+ +IG TL IPD IMG+TFLAAGTS+PD IA +VA+ G GDMA+SN+IGSNVFDIL+ LGLPW ++T +N GSE+ + S L+++ + LL +V + + I VN WKL+ LG L LY + + S + E N+ N P C
Sbjct: 321 NKTKWLISWPLLLLLFFTIPNCAKPR-WEKYFMLSFLLSTVWIAIFSYFMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGLPWALQTMAINYGSEVMINSRGLVYSVVLLLGSVALTILGIHVNHWKLDFKLGMYVLVLYAIFLCFSIMIEYNVFTFVNLPMC 516
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Match: slc24a4b (solute carrier family 24 member 4b [Source:ZFIN;Acc:ZDB-GENE-081031-75]) HSP 1 Score: 182.185 bits (461), Expect = 4.323e-51 Identity = 91/166 (54.82%), Postives = 127/166 (76.51%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVI----GVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY 720
C +I EFP D T +ERK+GG++ H+F ++Y+F ALA++CD++FV SLE++ E + DVAGATFMAAGSSAPEL TSVI GVF+TK DVG+ TIVGSAVFN+LCII +CG+F G ++ L WW +FRD + Y +SIIALI+ + D ++ W+E++I++ +Y
Sbjct: 1 CVVAAINEFPKDIFTNEERKHGGLLLHVFCTMYMFYALALVCDDFFVPSLEKISERLQLSEDVAGATFMAAGSSAPELFTSVIVWCEGVFVTKGDVGVGTIVGSAVFNILCIIGVCGLFAGQIVRLTWWSLFRDSVFYTISIIALILFICDEIVSWWESVILIMLY 166 HSP 2 Score: 181.415 bits (459), Expect = 8.872e-51 Identity = 95/207 (45.89%), Postives = 139/207 (67.15%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPR 1587
+P+ C++L W+ P+ + YFT+P+C K W F+ +F IS IWI+V +Y++VWM+ +IG TL IPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSNVFDIL+ LGLPW ++T ++ GS + + S LI++ + LL++V + V I +N WKL+R LG L +Y + + S + E N+ N P C +
Sbjct: 341 LRIPDGVCNKLKWMFAWPLGLLLYFTVPNCAKAR-WENWFMASFVISTIWIAVFSYVMVWMVTVIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILVGLGLPWALQTLLVDYGSHVEINSRGLIYSVVLLLASVGITVLGIYLNNWKLDRKLGLACLFVYAVFLCFSIMIEFNVFTFVNLPMCRK 546
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Match: slc24a1 (solute carrier family 24 member 1 [Source:ZFIN;Acc:ZDB-GENE-060503-191]) HSP 1 Score: 163.696 bits (413), Expect = 2.262e-44 Identity = 95/203 (46.80%), Postives = 135/203 (66.50%), Query Frame = 1
Query: 256 EFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRL--------PRLKGYGEEHNPLISQNLP 840
++P D T ++RK G ++ H+ IY+F+ALAI+CDE+FV +L + E I DVAGATFMAAG SAPEL TS+IGVFI+ S+VGI TIVGSAVFN+L +I +C +F ++ L WWP+FRD Y + + LII D LIQW+E++++L YV+Y++ + +N + FV QRL P G++++P NLP
Sbjct: 18 DYPRDLFTLEQRKRGAVVLHMLGMIYMFIALAIVCDEFFVPALGVITEKLAISDDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGMCAVFSREILVLTWWPLFRDVSFYIVGLSMLIIFFLDNLIQWWESMLLLSCYVSYVVFMKFNAKVESFVKQRLSMDPPAKIPGGIDEGDKNDP----NLP 216 HSP 2 Score: 126.716 bits (317), Expect = 2.283e-31 Identity = 79/212 (37.26%), Postives = 123/212 (58.02%), Query Frame = 1
Query: 955 SPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRT 1590
P P S ++ +V +LP+ + T+PD R RK F+VTFF S++WI++ +Y++VW +G+T+ I + IMGLT LAAGTSIPD I +VA+ G GDMA+S+S+GSN+FDI + L +PW + S + + + V S+ L + L ++ ++ TI +W +N+ LGF LY + + +S + E L CP T
Sbjct: 350 KPLSMRWPESTKKQISYVFLLPLVLPLWITLPDVRNHRS-RKFFMVTFFGSILWIAIFSYLMVWWAHQVGETIGITEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPMPWLM-FSLVKGFAPVQVSSNGLFCAIVLLFLMLLFVILTIAACRWHMNKLLGFCMFLLYFVFLIISVMLETRTLH------CPVT 553
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Match: SLC8B1 (solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]) HSP 1 Score: 58.9214 bits (141), Expect = 1.106e-9 Identity = 34/103 (33.01%), Postives = 54/103 (52.43%), Query Frame = 1
Query: 1027 AICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGL 1335
A+ F + P ++ F +S +W++ +V ++ G I T++GLT LA G S+PD +A +A+ GY MAIS G VF+IL+ +GL
Sbjct: 184 AVVAFITTSEQPPAFQLAFAVLGFVVSALWMNAIANEVVNLLQTFGVVFGISSTVLGLTLLAWGNSVPDFVADITMARQGYPRMAISACFGGIVFNILVGIGL 286
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000794.1 (pep scaffold:Pmarinus_7.0:GL477892:73629:76552:-1 gene:ENSPMAG00000000728.1 transcript:ENSPMAT00000000794.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 53.1434 bits (126), Expect = 1.236e-7 Identity = 41/110 (37.27%), Postives = 54/110 (49.09%), Query Frame = 1
Query: 307 IFHIFVSIYLFVALAIICDEYFVS-----SLER--------------LCEVFNIKHDVAGATFMAAGSSAPELCTSVI---GVFITKSDVGISTIVGSAVFNVLCIIAIC 570
I + IY+F+ ++II D + S S E+ V+N V+ T MA GSSAPE+ S+I G D+G STIVGSA FN+ IIAIC
Sbjct: 82 IVYFVALIYMFLGVSIIADRFMASIEVITSQEKEITIKRPDGETTTTTVRVWN--ETVSNLTLMALGSSAPEILLSIIEICGHGFEAGDLGPSTIVGSAAFNMFVIIAIC 189
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006683.1 (pep scaffold:Pmarinus_7.0:GL476710:281470:285756:-1 gene:ENSPMAG00000006040.1 transcript:ENSPMAT00000006683.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 51.2174 bits (121), Expect = 2.521e-7 Identity = 26/87 (29.89%), Postives = 49/87 (56.32%), Query Frame = 1
Query: 1096 FFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVA-KDGYGDMAISNSIGSNVFDILICLGLPWFIRT 1353
F +S+ I + T ++ + G T+ + D++ + F+A GTSIPD A + A +D + D ++ N GSN ++ + +G+ W I +
Sbjct: 126 FLVSISVIGLLTAMIGDLASHFGCTVGLKDSVTAVVFVALGTSIPDTFASKVAAVQDQFADASVGNVTGSNAVNVFLGIGIAWTIAS 212
BLAST of slc24a-8 vs. Ensembl Nematostella
Match: EDO32048 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW69]) HSP 1 Score: 307.76 bits (787), Expect = 4.731e-99 Identity = 189/489 (38.65%), Postives = 290/489 (59.30%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQ----RLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIME--TGDVDSIHSRI--RLDEDMTNLG--ESPTI-----------------------------FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
NCT +I EFP+DF T+++R+ G ++ + +S+Y+F A+AI+CD+YFV LE +C+ ++ DVAGATFMA GSSAPEL SVIGVFITK D+G+ TI+GSAVFNVL +I +CG+ G+V++L WWPM RD + Y S++ L+++L D ++ W EA M+ Y Y++I+Y+N + ++ + P K E ++ P D+ E EI++ G D+ + R+ E N +SP I F P + R+ WV LP+ + TIPD +KP K +++F I ++WI V +Y+LVWM+ +IG T IPD++MGL+ +A G+S+PD ++ VA+ G GDMA+S+++GSNVFDIL+CLG+PW I+T+ S + + S L + +L ++ V + I KW LN+ +G I+L Y + +++S + E+N GNFN P C
Sbjct: 1 NCTPPAILEFPDDFFTQRQRQRGAVVLNFIISLYMFWAVAIVCDDYFVPCLEIICDRLGLQTDVAGATFMALGSSAPELFASVIGVFITKGDIGVGTILGSAVFNVLFVIGVCGVGAGTVLYLAWWPMVRDSVFYLFSLVGLMLVLMDNVVVWSEATAMVSFYSVYLLIMYFNPRIEAYLYRVTKTTTPEYKSDLHEQKATKTKYDPVQ--QTDNEVEAEILDNVNGSDDTTKKGLLGRIYELYFNKEKVKSPLIVGFGEHLAHHHEYEQHVPHDVPDLTLGSPFSPPENVWPRICWVLGLPINLSFFLTIPDVKKPSC-EKWVVLSFIICIVWIGVTSYVLVWMVTVIGYTFLIPDSVMGLSLVAFGSSVPDCLSSLFVARKGDGDMAVSHTVGSNVFDILLCLGIPWLIKTTVWEYDSSVVINSHGLFISCFFILGSIAVTLIIIWYYKWTLNKKVGCIYLVFYFIFMSISVVVEMNAFGNFNPPMC 486
BLAST of slc24a-8 vs. Ensembl Nematostella
Match: EDO48007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKL4]) HSP 1 Score: 296.975 bits (759), Expect = 1.313e-95 Identity = 179/438 (40.87%), Postives = 262/438 (59.82%), Query Frame = 1
Query: 235 CTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEE-EIMETGDVDSIHSRIRLDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFE 1545
C +IEEFP D +T+ +R GG++ H+ S++LF AL ++C+++FV+SL R+ +K DVAGATFMA GSSAP L ++I +F T+ D+G+ TIVGS +FN L IIA+C I G + L +P+ RD +Y S+I L++ + D + WYE LI + +Y YI+I+Y + ++ L E E + ++ + + ED T + P C R WV LP + Y TIPDCRK WRK +LVTF ++VIW++V +Y LVWM+ +IG T IP+ +MG+TFLAAG+S+PDAIA +VAK G GDMA+SN IGSNVFD+L CLG+PW I+++FL PG + ++S ++ FT+ L+ ++ V I NKWKLN +G FL +Y L + +++ E
Sbjct: 1 CRPPNIEEFPPDVLTQDQRFYGGVMLHVIFSLHLFCALTVVCEDFFVASLNRISMCLGLKPDVAGATFMAVGSSAPTLFIAIISIFFTEGDIGLGTIVGSTIFNTLFIIALCAIGSGVTLQLACYPISRDSTVYVASVIVLMVSIYDNKVYWYEGLIFVIVYAIYIVIMY------------------FNDQVEGLCKTVKKKLKKKKVKPEGEGQGVDEDGGEESEDELNKSEDWGFHDTPRTRLKPPEGACARALWVFTLPSILVFYVTIPDCRKK-TWRKFYLVTFTVAVIWMAVLSYFLVWMVAIIGYTYTIPECVMGMTFLAAGSSLPDAIASLVVAKQGSGDMAVSNCIGSNVFDML-CLGIPWLIKSAFLQPGKPVVIQSENIFFTSAMLIGSIAVTFLLIQFNKWKLNVKVGIAFLIMYFLFLIVATYIE 418
BLAST of slc24a-8 vs. Ensembl Nematostella
Match: EDO48300 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJP5]) HSP 1 Score: 184.111 bits (466), Expect = 4.741e-55 Identity = 107/207 (51.69%), Postives = 159/207 (76.81%), Query Frame = 1
Query: 961 TIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
+IF +P + W+ MLP++ + + TIPDCR+P WRK + +TF ISV+WI+ +YILVWM+ +IG TL+IPD +MGLTF+AAG+S+PD I+ +VA+ G GDMA+SN+IGSNVFDIL+CLGLPW ++T+ + G + V S S+I+T+I+L TVVV + +++N+W+LNR LG +F+ LY+ I++++LFELN++G+FN P C
Sbjct: 4 SIFVMPEGTLKAIIWIIMLPISCLFFITIPDCRRPR-WRKWYFLTFLISVLWIAGLSYILVWMVEIIGYTLEIPDVVMGLTFVAAGSSVPDGISSLIVARHGDGDMAVSNTIGSNVFDILLCLGLPWLLKTTAVEHGGVVTVLSGSIIYTSISLFGTVVVTILLVVLNRWRLNRLLGCVFMILYIAFISVATLFELNVIGDFNLPIC 209
BLAST of slc24a-8 vs. Ensembl Nematostella
Match: EDO48302 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJP9]) HSP 1 Score: 172.94 bits (437), Expect = 6.723e-51 Identity = 83/116 (71.55%), Postives = 97/116 (83.62%), Query Frame = 1
Query: 229 KNCTTRSIEEFPNDFMTRKER-KNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICG 573
KNC SI +FP+DFMT+ +R K GGI+FH+FV+IY F ALA +CDEYFVSSLER+C+ N+K DVAGATFMAAGSSAPE TSVIGVFITK D+GI TIVGSAVFN+L I+AIC
Sbjct: 65 KNCVNPSISDFPSDFMTQYQRQKQGGIVFHVFVAIYTFAALATVCDEYFVSSLERICDGLNLKSDVAGATFMAAGSSAPEFFTSVIGVFITKGDIGIGTIVGSAVFNILFIVAICA 180
BLAST of slc24a-8 vs. Ensembl Nematostella
Match: EDO48006 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKL3]) HSP 1 Score: 167.933 bits (424), Expect = 4.360e-45 Identity = 98/274 (35.77%), Postives = 154/274 (56.20%), Query Frame = 1
Query: 775 QRLPRLKG--YGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLGES--------------PTI-FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFE 1545
+L L G + +++ I + L+ E + G +D + RI ED T G S P+ F P++F R+ W+ MLPV Y T+PDCR W + TF +S+IW++ +Y+LVW + +IG+T IP+ IMGLT LAAG+S+PD ++ +VAK G GDMA++N IGSN+FD+L CLGLPW + T+ ++P S + + S +++ ++ L TV+ +V+ I +N W+L+R LG I Y + + + E
Sbjct: 330 NKLTELDGATHNKQNEDKIDEKNENEHNKLNEHCEGDSHNEGKMDKENERIEQKEDATKSGASGSHQNTPSHIHGFKPSCPFTPPSTFSKRIVWIFMLPVHLAFYVTMPDCRVKK-WEAWYPATFALSIIWMAALSYVLVWTVSIIGETFSIPEYIMGLTLLAAGSSVPDVMSSLIVAKHGMGDMALANCIGSNIFDVL-CLGLPWLLATTAVHPNSVVLIHSGHIVYVSMCLFGTVLTIVSAIHLNGWRLDRRLGVILFIAYAFFLTSAVILE 601 HSP 2 Score: 141.739 bits (356), Expect = 4.795e-36 Identity = 75/150 (50.00%), Postives = 110/150 (73.33%), Query Frame = 1
Query: 277 TRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVA 726
T +ER++G +I H F+ +Y FVALAI+CD YF +SLE+LC+ I DVAGATFMAAGSS P L ++ VF+ + D+G+ TI+GS++FN+L I AICG+F G VI L+ WP+ RD +Y ++++ L+I+++D +I +YEALI +Y
Sbjct: 41 TLQERRHGAVIIHTFICLYCFVALAILCDNYFCASLEKLCKRLRIPTDVAGATFMAAGSSMPTLFIAIASVFMGEGDIGLGTIIGSSMFNILFITAICGLFSGMVISLHTWPIVRDSCVYVVNLVGLLIVIHDNVIHFYEALIFPVLYTG 190
BLAST of slc24a-8 vs. Ensembl Medaka
Match: slc24a5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:101173921]) HSP 1 Score: 348.591 bits (893), Expect = 4.406e-114 Identity = 208/500 (41.60%), Postives = 305/500 (61.00%), Query Frame = 1
Query: 88 KKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRL-----KGYGE--EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDE-DMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
KK + + + G + F + + + R L C + EFP+ F T +ERK+GG++ + + Y+ +A+AI+CD+YF+ SLE + E + DVAGATFMAAGSSAPEL T+ +GVF+TK D+G+STIVGSAV+N+L I A CGI L WP+FRDC+ Y +S+ A+I I++D + WYEA +L +Y YI++L ++ + FV+++L G + E PL N T + S + + D H + L + + E ++F VP S R+ WV LPV + + T+PDCR+ W++ F++TFF+S +WIS TY+LVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A +VA++G DMA+SN +GSNVFD+L CLGLPWFI+T F++ + + V SS L+F + TLL ++V L + +N WKL+ LG + L Y+L LS L+EL I+GN
Sbjct: 9 KKTRKDFIPYFLGFVIFLYGTFHLISFTAKTAEFAPTVRVRRALENETECISPQASEFPDGFFTVQERKDGGLVIYFMIIFYMLLAVAIVCDDYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGILASVARRLTCWPLFRDCLAYGISVAAVIGIISDNKVYWYEAACLLLVYGVYIVVLCFDLRISEFVLRKLSPCCTCLSSGSADKMETQPLTGWNDDTRLRICGRSRTDSGIFHDDSGYSHLSLSLHGLNEISDAEQKSVFSVPESDLKRILWVLSLPVIVLLFLTVPDCRRR-FWKQWFMITFFMSAVWISAFTYVLVWMVTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKADMAMSNIVGSNVFDML-CLGLPWFIKTVFVDTINPVEVNSSGLVFVSCTLLLSIVFLFVAVHINGWKLDWKLGLVSLICYILFATLSILYELGIIGN 506
BLAST of slc24a-8 vs. Ensembl Medaka
Match: slc24a5 (solute carrier family 24 member 5 [Source:NCBI gene;Acc:101173921]) HSP 1 Score: 343.584 bits (880), Expect = 9.462e-113 Identity = 202/452 (44.69%), Postives = 292/452 (64.60%), Query Frame = 1
Query: 232 NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRL-----KGYGE--EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDE-DMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGN 1563
C + EFP+ F T +ERK+GG++ + + Y+ +A+AI+CD+YF+ SLE + E + DVAGATFMAAGSSAPEL T+ +GVF+TK D+G+STIVGSAV+N+L I A CGI L WP+FRDC+ Y +S+ A+I I++D + WYEA +L +Y YI++L ++ + FV+++L G + E PL N T + S + + D H + L + + E ++F VP S R+ WV LPV + + T+PDCR+ W++ F++TFF+S +WIS TY+LVWM+ ++G+TL IPDT+MGLT LAAGTSIPD +A +VA++G DMA+SN +GSNVFD+L CLGLPWFI+T F++ + + V SS L+F + TLL ++V L + +N WKL+ LG + L Y+L LS L+EL I+GN
Sbjct: 14 ECISPQASEFPDGFFTVQERKDGGLVIYFMIIFYMLLAVAIVCDDYFLPSLEVISERLGLSQDVAGATFMAAGSSAPELVTAFLGVFVTKGDIGVSTIVGSAVYNLLGICAACGILASVARRLTCWPLFRDCLAYGISVAAVIGIISDNKVYWYEAACLLLVYGVYIVVLCFDLRISEFVLRKLSPCCTCLSSGSADKMETQPLTGWNDDTRLRICGRSRTDSGIFHDDSGYSHLSLSLHGLNEISDAEQKSVFSVPESDLKRILWVLSLPVIVLLFLTVPDCRRR-FWKQWFMITFFMSAVWISAFTYVLVWMVTVVGETLGIPDTVMGLTLLAAGTSIPDTVASVMVAREGKADMAMSNIVGSNVFDML-CLGLPWFIKTVFVDTINPVEVNSSGLVFVSCTLLLSIVFLFVAVHINGWKLDWKLGLVSLICYILFATLSILYELGIIGN 463
BLAST of slc24a-8 vs. Ensembl Medaka
Match: slc24a4b (solute carrier family 24 member 4 [Source:NCBI gene;Acc:101164447]) HSP 1 Score: 196.052 bits (497), Expect = 5.112e-55 Identity = 119/274 (43.43%), Postives = 166/274 (60.58%), Query Frame = 1
Query: 193 ELHGTGRKLLGL-------KNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSR---IRLDEDMTNLGESPTIFEVPNS 984
+L GR+LL L KNC+ I EFP D + ERK+G ++ HI ++Y+F+ALAI CDEYFV+SLE++CE ++ DVAGATFMAAGSSAPEL SVIGVFIT DVG+ TIVGSAVFN+LCII +CGIF G V+ L W +FRD Y LS++ALI + D I W+E+LI++ MY YI+++ +N ++ F + + G ++ T + + D ++ +SR + +DE M SP+ F P +
Sbjct: 64 DLDHLGRRLLALSENETEPKNCSEPGIHEFPEDLFSNAERKSGAVLLHIVATLYMFLALAITCDEYFVTSLEKICEKLDLSEDVAGATFMAAGSSAPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGIFAGQVVMLTRWAVFRDSFYYILSVVALIAFIYDEKIDWWESLILVVMYAGYILVMKFNSSMQRFFTGKSNKNVANGNAAASSEMEDGNTCYYIWDDDPSSPLLLAVKPSKAYSRGSVVMVDEIMN---ASPSKFRFPEA 334 HSP 2 Score: 171.785 bits (434), Expect = 3.055e-46 Identity = 102/250 (40.80%), Postives = 159/250 (63.60%), Query Frame = 1
Query: 865 SEEEEIMETG---DVDSIHSRIRLD-----EDM-TNLGESPTI--FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
+E +++++T + I ++ ++ ED T E+ TI F VP+ ++ W+ P+ + +FTIP+C KP W + F+++F +S +WI++ +Y++VWM+ + G TL IPD IMG+TFLAAGTS+PD IA +VA+ G GDMA+SN+IGSNVFDIL+ LG+PW I+T ++ GSE+ + S L+++ + LL +V + V I NKW+L+ LG L LY + + S L E N+ N P C
Sbjct: 359 TERQKLVQTANGVETQVIDGKVEIENGNVPEDKPTEAEENDTISPFHVPSGIGSKVKWLLSWPLLLLLFFTIPNCAKPR-WERFFMLSFILSTVWIAIFSYVMVWMVTVAGYTLGIPDVIMGITFLAAGTSVPDCIASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWAIQTICVSYGSEVAINSRGLVYSVVLLLGSVALTVLGIHFNKWRLDFKLGVYVLVLYAVFLCFSILIEYNVFTFVNLPMC 607
BLAST of slc24a-8 vs. Ensembl Medaka
Match: ENSORLT00000003048.2 (solute carrier family 24 member 3 [Source:NCBI gene;Acc:101170984]) HSP 1 Score: 187.963 bits (476), Expect = 1.073e-51 Identity = 93/166 (56.02%), Postives = 120/166 (72.29%), Query Frame = 1
Query: 223 GLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY 720
G KNCTT ++ EFP D T +ER G + H+ + Y+F ALA++CD+YFV SLE++CE ++ DVAGATFMAAGSSAPEL TSVIGVFITK DVG+ TIVGSAVFN+LCII +CG F G + L+ W + RD Y SI ALI + D + W+E+L+++ MY
Sbjct: 102 GSKNCTTPALHEFPTDLFTNEERTEGAVALHVLCTFYMFCALALVCDDYFVPSLEKICERLDLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGFFAGQAVKLSHWALLRDSTYYTFSITALIAFIYDENVCWWESLVLVLMY 267 HSP 2 Score: 179.489 bits (454), Expect = 1.034e-48 Identity = 97/205 (47.32%), Postives = 141/205 (68.78%), Query Frame = 1
Query: 967 FEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F+VP C++L W+ M P++ + +FT+P+C K W + F+V+FF + IWI+ +YI+VWM+ +IG TL +PD IMG+TFLAAGTS+PD +A +VA+ G GDMAISNSIGSNVFDIL+ LGLPW ++T ++ GS I + S L+F+ LL++V V + +NKW L+ LG + L +Y + + +S L E N+ N P C
Sbjct: 458 FKVPAGVCNKLKWLFMWPLSLLLFFTVPNCGKRR-WERWFMVSFFTATIWIAGLSYIMVWMVTVIGFTLGLPDVIMGITFLAAGTSVPDCMASVIVARQGMGDMAISNSIGSNVFDILVGLGLPWALQTLCIDYGSVIHLNSRGLVFSVGLLLASVFFTVLGVHLNKWTLDWRLGLVCLVMYAVFLCISILIEFNVFIFVNLPMC 661
BLAST of slc24a-8 vs. Ensembl Medaka
Match: ENSORLT00000009286.2 (sodium/potassium/calcium exchanger 3 [Source:NCBI gene;Acc:101155536]) HSP 1 Score: 182.57 bits (462), Expect = 4.321e-50 Identity = 91/158 (57.59%), Postives = 121/158 (76.58%), Query Frame = 1
Query: 247 SIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY 720
+I EFP D TR++RKNG ++ H +IY+F ALAI+CD+YFV SLE++ E + DVAGATFMAAGSSAPEL TS+IGVFITK DVG+ TIVGSAVFN+L II +CGIF G + L WW +FRD Y L+++ALI+++ D + W+E+L+++ MY
Sbjct: 72 AIHEFPQDIFTREQRKNGAVLLHALCAIYMFYALAIVCDDYFVPSLEKISENLQLSEDVAGATFMAAGSSAPELFTSLIGVFITKGDVGVGTIVGSAVFNILVIIGLCGIFAGQTVVLTWWSLFRDATYYILAVLALILVIYDDTVLWWESLLLITMY 229 HSP 2 Score: 152.14 bits (383), Expect = 2.954e-39 Identity = 89/191 (46.60%), Postives = 131/191 (68.59%), Query Frame = 1
Query: 970 EVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLF 1542
+P S R+ WV P++ + Y T+P+C P W + F+VTF S +WI+V +Y +VWM+ +I TLDIPD IMG+TFLAAGTS+PD +A +VA+ G GDMA+SNSIGSN+FDIL+ LG PW +RT ++ GS + + + L+++ I LL++V + V ++ +N W+L+R LG L LY + + S LF
Sbjct: 412 RIPGSCGARVKWVITWPLSLLLYCTVPNCVLPR-WHRWFMVTFVASTMWIAVFSYQMVWMVTIISYTLDIPDYIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVDHGSTVSINNKGLVYSVILLLASVFLTVISVHLNHWRLDRRLGLGLLFLYAIFLLCSILF 601
BLAST of slc24a-8 vs. Planmine SMEST
Match: SMESG000030115.1 (SMESG000030115.1) HSP 1 Score: 858.21 bits (2216), Expect = 0.000e+0 Identity = 480/484 (99.17%), Postives = 482/484 (99.59%), Query Frame = 1
Query: 148 MYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNL-GESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS 1596
MYFFTKFKSNSDTMSELHGT RKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVS+YLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEAL+MLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNL GESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS
Sbjct: 1 MYFFTKFKSNSDTMSELHGTSRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSMYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEALVMLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLEGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPCPRTSS 484
BLAST of slc24a-8 vs. Planmine SMEST
Match: SMESG000030115.1 (SMESG000030115.1) HSP 1 Score: 811.216 bits (2094), Expect = 0.000e+0 Identity = 456/460 (99.13%), Postives = 458/460 (99.57%), Query Frame = 1
Query: 82 MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNL-GESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIM 1458
MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGT RKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVS+YLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEAL+MLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNL GESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIM
Sbjct: 1 MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTSRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSMYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCIIYCLSIIALIIILNDGLIQWYEALVMLFMYVAYIIILYYNGNLYGFVIQRLPRLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSRIRLDEDMTNLEGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVESSSLIFTTITLLSTVVVLVATIM 460
BLAST of slc24a-8 vs. Planmine SMEST
Match: SMESG000030111.1 (SMESG000030111.1) HSP 1 Score: 366.696 bits (940), Expect = 4.780e-123 Identity = 194/364 (53.30%), Postives = 263/364 (72.25%), Query Frame = 1
Query: 91 KNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKNCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMYVAXXXXXXXXXXXXXFVIQRLP-RLKGYGEEHNPLISQNLPTSFGLLDSSEEEEIMETGDVDS---IHSRIR--LDEDMTNLGESPTIFEVPNSFCHRLYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIG 1164
K H ++ KI+ YFSL+ G FF K + G RKLL L NCT RS+EEFP+DFMTR ++KNGG++FHI +S YLF+A+AI+CD+YFVSSLE +CEV +++HDVAGATFMA G SAPELCT+VI VFIT SDVG+STI+GSA+FNVLC+ AICGIF G VI L WWP+FRDC+IYC++II L I+LND L+ WYE LIML +Y YI++LY N ++Y V++ LP + E PL +N + L+DS +++ +E D++S + RI +ED + ++F +P+SF RL+WV MLPV +C+ TIPDCR+PGI++KLF +TF +S++WI++ Y+LVWMIC+ G
Sbjct: 4 KKHKSFLKIILCYFSLIFGSIFFLKVNDIGGKDANFDGKSRKLLSLSNCTKRSVEEFPDDFMTRVDKKNGGVLFHIVMSAYLFMAIAIVCDDYFVSSLESICEVLHLRHDVAGATFMALGGSAPELCTAVIAVFITDSDVGVSTIIGSALFNVLCVTAICGIFAGKVIQLTWWPVFRDCMIYCITIITLTIVLNDELVHWYEGLIMLIIYSLYILLLYKNDSVYQIVVKLLPISKRKLDPEKKPLFYENDSLAKSLIDSENDDD-LEKEDLNSNFQTNKRIHGCDNEDSIEGDKLESMFAIPDSFVSRLHWVTMLPVTVLCFLTIPDCRRPGIYKKLFFLTFLMSLVWITICIYLLVWMICITG 366
BLAST of slc24a-8 vs. Planmine SMEST
Match: SMESG000010390.1 (SMESG000010390.1) HSP 1 Score: 309.686 bits (792), Expect = 3.935e-99 Identity = 195/508 (38.39%), Postives = 294/508 (57.87%), Query Frame = 1
Query: 154 FFTKFKSNSDTMS-ELHGTGRKLLGLK-NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY----VAXXXXXXXXXXXXXFVIQRLPRLKGYGEE--------HNPLISQNLPTSFGLL---DSSEEEEIMETGDVDSIHSR----IRLDEDMTN-------LGESPTIFEVPNSFCHR----LYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F+ +K + + ++ + R+LL K NC+ ++I+ FP D +++ R++G +I H ++IY+F+ LAI+C++YFV LE +CE ++ DVAGATFMAAGSSAPEL T++IGVFI K D+ + +VGSA +N++ +I + +F +VI LNWWP+FRDC Y +SII L +++ D L+ WYEA++ +F Y V V + LP E N + TS G+ +E +E E+G + +R D D L E+P+ R Y+ P+ +IPDCR+ +RK F +TF S IWI + +YI++WMI +IG TL IPD++MGLTF+AAG+S+PDAIA LV ++G GDMA+SN++GSNVFDILIC+G+PW I+ L G I + S L++ TITL TV LV + WK+ + G+I + +Y+ + + ++ELN+ G + P C
Sbjct: 8 FYANYKHDINPINNDKSYISRQLLSYKANCSPKAIDNFPEDLFSKEARQSGALIIHFLITIYMFIGLAIVCEDYFVPCLECICENLKLQPDVAGATFMAAGSSAPELATTIIGVFIAKDDIALGAVVGSADYNLMFVIGLSALFAKTVIQLNWWPLFRDCAFYSISIILLALVIYDNLVYWYEAIVFIFFYGIYIVLNYFNKSLELWAKMLVTKYLPNCTINNENLSDEAFLMSNEVAEDLHTTSTGIEMINSGTESDEDYESGKLIGTRNRNGSCCSSDIDFAKKTGCAMCLRSCFATLELPDKKKARWWNYFYYGLCYPLRFFLCVSIPDCRER-FFRKWFWITFINSCIWIGMYSYIMIWMITVIGFTLGIPDSVMGLTFIAAGSSVPDAIASVLVVREGQGDMAVSNAVGSNVFDILICMGVPWLIKC--LTLGKPILIYSKGLLYATITLFMTVFGLVFITHLYSWKMTKSFGYILIIIYVAFLVVCCMYELNVFGLVHPPEC 512
BLAST of slc24a-8 vs. Planmine SMEST
Match: SMESG000010390.1 (SMESG000010390.1) HSP 1 Score: 308.145 bits (788), Expect = 1.014e-98 Identity = 193/500 (38.60%), Postives = 293/500 (58.60%), Query Frame = 1
Query: 154 FFTKFKSNSDTMS-ELHGTGRKLLGLK-NCTTRSIEEFPNDFMTRKERKNGGIIFHIFVSIYLFVALAIICDEYFVSSLERLCEVFNIKHDVAGATFMAAGSSAPELCTSVIGVFITKSDVGISTIVGSAVFNVLCIIAICGIFVGSVIHLNWWPMFRDCXXXXXXXXXXXXXXXXXXXQWYEALIMLFMY----VAXXXXXXXXXXXXXFVIQRLPRLKGYGE---EHNPLISQNLPTSFGLLDSSEEEEIMETGDVDSIHSR----IRLDEDMTN-------LGESPTIFEVPNSFCHR----LYWVAMLPVAAICYFTIPDCRKPGIWRKLFLVTFFISVIWISVATYILVWMICLIGDTLDIPDTIMGLTFLAAGTSIPDAIAGYLVAKDGYGDMAISNSIGSNVFDILICLGLPWFIRTSFLNPGSEIPVEXXXXXXXXXXXXXXXXXXXATIMVNKWKLNRFLGFIFLALYMLIIALSSLFELNILGNFNRPPC 1581
F+ +K + + ++ + R+LL K NC+ ++I+ FP D +++ R++G +I H ++IY+F+ LAI+C++YFV LE +CE ++ DVAGATFMAAGSSAPEL T++IGVFI K D+ + +VGSA +N++ +I + +F +VI LNWWP+FRDC Y +SII L +++ D L+ WYEA++ +F Y V V + LP E + L+S + L +S E++ +G +R D D L E+P+ R Y+ P+ +IPDCR+ +RK F +TF S IWI + +YI++WMI +IG TL IPD++MGLTF+AAG+S+PDAIA LV ++G GDMA+SN++GSNVFDILIC+G+PW I+ L G I + S L++ TITL TV LV + WK+ + G+I + +Y+ + + ++ELN+ G + P C
Sbjct: 8 FYANYKHDINPINNDKSYISRQLLSYKANCSPKAIDNFPEDLFSKEARQSGALIIHFLITIYMFIGLAIVCEDYFVPCLECICENLKLQPDVAGATFMAAGSSAPELATTIIGVFIAKDDIALGAVVGSADYNLMFVIGLSALFAKTVIQLNWWPLFRDCAFYSISIILLALVIYDNLVYWYEAIVFIFFYGIYIVLNYFNKSLELWAKMLVTKYLPNCTINNENLSDEAFLMSNEVAED--LHTTSTGIEMINSGTESGTRNRNGSCCSSDIDFAKKTGCAMCLRSCFATLELPDKKKARWWNYFYYGLCYPLRFFLCVSIPDCRER-FFRKWFWITFINSCIWIGMYSYIMIWMITVIGFTLGIPDSVMGLTFIAAGSSVPDAIASVLVVREGQGDMAVSNAVGSNVFDILICMGVPWLIKC--LTLGKPILIYSKGLLYATITLFMTVFGLVFITHLYSWKMTKSFGYILIIIYVAFLVVCCMYELNVFGLVHPPEC 502 The following BLAST results are available for this feature:
BLAST of slc24a-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc24a-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc24a-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc24a-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc24a-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc24a-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001319 ID=SMED30001319|Name=slc24a-8|organism=Schmidtea mediterranea sexual|type=transcript|length=1611bpback to top protein sequence of SMED30001319-orf-1 >SMED30001319-orf-1 ID=SMED30001319-orf-1|Name=SMED30001319-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=506bp MLKKNHGAYFKILFFYFSLVIGMYFFTKFKSNSDTMSELHGTGRKLLGLKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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