deoxynucleoside triphosphate triphosphohydrolase SAMHD1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001300 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Match: SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]) HSP 1 Score: 174.096 bits (440), Expect = 1.986e-47 Identity = 138/452 (30.53%), Postives = 222/452 (49.12%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVEN--KLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A ++ +Y + IT G + S+ I + + D+ + + P +I+ +IE R L K + K+ KE+ +L + +++ DF + + + NP+ V FY K P +N + L+ E ++ ++ +K
Sbjct: 133 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF---LKADDYIE--ITGAGGKKYRISTAIDDMEAY-TKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKK 556
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Match: SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]) HSP 1 Score: 174.096 bits (440), Expect = 3.587e-47 Identity = 138/452 (30.53%), Postives = 222/452 (49.12%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVEN--KLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A ++ +Y + IT G + S+ I + + D+ + + P +I+ +IE R L K + K+ KE+ +L + +++ DF + + + NP+ V FY K P +N + L+ E ++ ++ +K
Sbjct: 133 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF---LKADDYIE--ITGAGGKKYRISTAIDDMEAY-TKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKK 556
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Match: SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]) HSP 1 Score: 174.096 bits (440), Expect = 3.587e-47 Identity = 138/452 (30.53%), Postives = 222/452 (49.12%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVEN--KLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A ++ +Y + IT G + S+ I + + D+ + + P +I+ +IE R L K + K+ KE+ +L + +++ DF + + + NP+ V FY K P +N + L+ E ++ ++ +K
Sbjct: 133 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF---LKADDYIE--ITGAGGKKYRISTAIDDMEAY-TKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKK 556
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Match: SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]) HSP 1 Score: 167.933 bits (424), Expect = 1.988e-46 Identity = 107/280 (38.21%), Postives = 157/280 (56.07%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A
Sbjct: 109 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF 366
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Match: SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:15925]) HSP 1 Score: 169.859 bits (429), Expect = 7.989e-46 Identity = 107/280 (38.21%), Postives = 157/280 (56.07%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A
Sbjct: 133 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF 390
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Celegans
Match: ZK177.8 (pep chromosome:WBcel235:II:5509032:5513775:-1 gene:WBGene00022673.1 transcript:ZK177.8b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK177.8) HSP 1 Score: 136.346 bits (342), Expect = 1.663e-34 Identity = 103/295 (34.92%), Postives = 148/295 (50.17%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLR-VQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR-PHEELSVEIFKSLLNSSKLCYNRSIKFEI-----ELDE---KSIDLIGRIIIGKYN--EKIDG------------------------KKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
++IDT EFQRLR +KQ G+ VYP +SRF HS+GTF LA L LR Q ++ +TE+D+ C +AAL HD+GHG +SH ++ F +R HE++S+ I K ++N + IK E E DE KS+ LI +I GK + +DG +K +LF++V+N +G DVDK DYL RD G ++R+ + RVV D +G R+A + I + I +R LH Y+HK V+ +E L AL
Sbjct: 28 KLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLN---------ITESDLICTSVAALLHDVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPE------IKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDAL 307
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Celegans
Match: ZK177.8 (pep chromosome:WBcel235:II:5509028:5511208:-1 gene:WBGene00022673.1 transcript:ZK177.8b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK177.8) HSP 1 Score: 136.346 bits (342), Expect = 1.663e-34 Identity = 103/295 (34.92%), Postives = 148/295 (50.17%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLR-VQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR-PHEELSVEIFKSLLNSSKLCYNRSIKFEI-----ELDE---KSIDLIGRIIIGKYN--EKIDG------------------------KKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
++IDT EFQRLR +KQ G+ VYP +SRF HS+GTF LA L LR Q ++ +TE+D+ C +AAL HD+GHG +SH ++ F +R HE++S+ I K ++N + IK E E DE KS+ LI +I GK + +DG +K +LF++V+N +G DVDK DYL RD G ++R+ + RVV D +G R+A + I + I +R LH Y+HK V+ +E L AL
Sbjct: 28 KLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLN---------ITESDLICTSVAALLHDVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPE------IKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDAL 307
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Celegans
Match: ZK177.8 (pep chromosome:WBcel235:II:5509032:5513748:-1 gene:WBGene00022673.1 transcript:ZK177.8a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK177.8) HSP 1 Score: 136.346 bits (342), Expect = 2.003e-34 Identity = 103/295 (34.92%), Postives = 148/295 (50.17%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLR-VQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR-PHEELSVEIFKSLLNSSKLCYNRSIKFEI-----ELDE---KSIDLIGRIIIGKYN--EKIDG------------------------KKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
++IDT EFQRLR +KQ G+ VYP +SRF HS+GTF LA L LR Q ++ +TE+D+ C +AAL HD+GHG +SH ++ F +R HE++S+ I K ++N + IK E E DE KS+ LI +I GK + +DG +K +LF++V+N +G DVDK DYL RD G ++R+ + RVV D +G R+A + I + I +R LH Y+HK V+ +E L AL
Sbjct: 62 KLIDTVEFQRLRHLKQTGLVYLVYPNCEHSRFVHSLGTFSLAYALVDKLRHSQPSLN---------ITESDLICTSVAALLHDVGHGPFSHLFDGEFAKRNGSRFKHEDMSILIIKKIMNKPE------IKSEFACILGETDEEYAKSVTLITELISGKPFDFQDMDGFKDLPADVREETVKNEWAIIGCGPEKSFLFDVVSNSYNGHDVDKMDYLLRDSKASGVGITFSESTLERLFNHVRVVIDPNSGLKRIAYSIKCIGDLKAIGDSRQELHSKVYQHKAVRFMETLMVDAL 341
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Fly
Match: fal (gene:FBgn0028380 transcript:FBtr0347258) HSP 1 Score: 84.7297 bits (208), Expect = 1.692e-17 Identity = 82/300 (27.33%), Postives = 141/300 (47.00%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIY-VYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWE----KAFDDSIPTRPHEELSV----EIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIV--------ENP---EYRDEFITNVM 848
+I++ FQRL+ V QLG+ + + + + R++H +G + A + L ++ Y KL + + +EIAAL HD+GHG SH WE FD HEE ++ +IFK LN + + + + LI +I+G +E + Y+F+IV N+ GLDVDK+DYL RD + ++ D + R+ D +R A R ++ +F+ R+LLH Y++ +++ +F ++ I ++P E DE++ NV+
Sbjct: 19 EIVEHPLFQRLKHVHQLGLLPWAIDKKADHKRYDHCLGAYKSAQD--HLRAIERNSHYEPKLPDWC-----RQAVEIAALLHDIGHGPMSHAWELVTHHEFD-------HEENAMACVDKIFKDALN------QELVSLRDDGGGRGVQLIKALILGS-SENLPFPMLGHTYIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEM-DFDDVFLQARISPDGQRIEYRYADYHR----VYRLFEARSLLHVKAYQYPLTCAMDVIFVSVVQRIAPELLSIRSKDPKWLELTDEYVLNVI 292
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Fly
Match: fal (gene:FBgn0028380 transcript:FBtr0290284) HSP 1 Score: 84.7297 bits (208), Expect = 1.692e-17 Identity = 82/300 (27.33%), Postives = 141/300 (47.00%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIY-VYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWE----KAFDDSIPTRPHEELSV----EIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIV--------ENP---EYRDEFITNVM 848
+I++ FQRL+ V QLG+ + + + + R++H +G + A + L ++ Y KL + + +EIAAL HD+GHG SH WE FD HEE ++ +IFK LN + + + + LI +I+G +E + Y+F+IV N+ GLDVDK+DYL RD + ++ D + R+ D +R A R ++ +F+ R+LLH Y++ +++ +F ++ I ++P E DE++ NV+
Sbjct: 19 EIVEHPLFQRLKHVHQLGLLPWAIDKKADHKRYDHCLGAYKSAQD--HLRAIERNSHYEPKLPDWC-----RQAVEIAALLHDIGHGPMSHAWELVTHHEFD-------HEENAMACVDKIFKDALN------QELVSLRDDGGGRGVQLIKALILGS-SENLPFPMLGHTYIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEM-DFDDVFLQARISPDGQRIEYRYADYHR----VYRLFEARSLLHVKAYQYPLTCAMDVIFVSVVQRIAPELLSIRSKDPKWLELTDEYVLNVI 292
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Fly
Match: fal (gene:FBgn0028380 transcript:FBtr0321324) HSP 1 Score: 84.7297 bits (208), Expect = 1.692e-17 Identity = 82/300 (27.33%), Postives = 141/300 (47.00%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIY-VYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWE----KAFDDSIPTRPHEELSV----EIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIV--------ENP---EYRDEFITNVM 848
+I++ FQRL+ V QLG+ + + + + R++H +G + A + L ++ Y KL + + +EIAAL HD+GHG SH WE FD HEE ++ +IFK LN + + + + LI +I+G +E + Y+F+IV N+ GLDVDK+DYL RD + ++ D + R+ D +R A R ++ +F+ R+LLH Y++ +++ +F ++ I ++P E DE++ NV+
Sbjct: 19 EIVEHPLFQRLKHVHQLGLLPWAIDKKADHKRYDHCLGAYKSAQD--HLRAIERNSHYEPKLPDWC-----RQAVEIAALLHDIGHGPMSHAWELVTHHEFD-------HEENAMACVDKIFKDALN------QELVSLRDDGGGRGVQLIKALILGS-SENLPFPMLGHTYIFDIVHNRRCGLDVDKWDYLRRDNKRLKILSSAEM-DFDDVFLQARISPDGQRIEYRYADYHR----VYRLFEARSLLHVKAYQYPLTCAMDVIFVSVVQRIAPELLSIRSKDPKWLELTDEYVLNVI 292
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Zebrafish
Match: si:ch73-236c18.8 (si:ch73-236c18.8 [Source:ZFIN;Acc:ZDB-GENE-121214-113]) HSP 1 Score: 167.933 bits (424), Expect = 1.325e-45 Identity = 142/458 (31.00%), Postives = 214/458 (46.72%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWE-------------KAFDDSIP-TRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKY---NE-KIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL----KTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFS--RFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKG-NPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+I DT +FQRLR +KQLG VYP +S++RFEHSIG +LA L K L D E +T+ D C++IA LCHDLGHG SH ++ K D IP + HE++SV +F S++ S N + E L + + I +I G NE G+ K +L+EIVANK++G+DVDK+DY RD + G N D R+L F RV +NG + RD+E +++D+F+TR LHR Y+HK +E +F AL + + E I+ + + DYS + D +S +P DI+ +I R L K R V+N + N W+ + K K +++ + + + L K NP+ V FY+K P + L + +E ++ ++ S
Sbjct: 78 VKITDTPQFQRLRHLKQLGGTYLVYPGASHNRFEHSIGVAYLAGRLVKSLH--------DNQPELKITKQDFLCVQIAGLCHDLGHGPLSHVFDVLVIPEVKKIKKLKGLPDDIPESWKHEQMSVLMFDSIVKS----LNEEVLREHGLTDNDVIFIKELIEGAKASDNEWPYQGRNVEKSFLYEIVANKQNGIDVDKWDYFARDCHHLGIRNS---FDHLRLLKFARVC--VVNGRKHICFRDKEADNVYDMFRTRYTLHRQAYQHKIANIIEDMFAEALLLADRDLHEKKPADMLKISEAIKSVEDYS-----------KLTDEIFEQILSSTSPNLKESKDILDKIMRRKLPKFIREVRLTVKNMSKEELKNSWKAAV-KTYKPTDPTVTLTAEELPVYVVDLDHGMKDKNPIERVYFYSKRKPNEASTIEDYQLSSFLPKKFNEELVRVYYRGS 506
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Zebrafish
Match: samhd1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:553453]) HSP 1 Score: 169.088 bits (427), Expect = 1.510e-45 Identity = 136/446 (30.49%), Postives = 220/446 (49.33%), Query Frame = 3
Query: 24 IDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKL---CYNRSIKFE---IELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD------IVARIEERCLLKLFSRFRVENKLNDVTGN---EWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENK-GNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
IDT +FQRLR +KQLG V+P +S++RFEHSIG +LA L K L ++ E +T+ D+ C++IA LCHDLGHG +SH ++ F IP RP HE SV++F L+ + L + ++ I + E+ + ++ + G+ K +L+E+VANK +G+DVDK+DY RD + G N D +R L F RV E+ G + RD+E+ +++D+F TRN LHR Y+HK +E + A + +P + I G SS I + ++ DH + P+ I+ I R L K + E + DV+ +W KEL + K ++ ++ + DF +S + K NP+ +V FY K +P ++ + L+ E ++ ++ +K+
Sbjct: 115 IDTPQFQRLRHIKQLGGTYLVFPGASHNRFEHSIGVGYLAGCLVKAL--------NERQPELFITKQDILCVQIAGLCHDLGHGPFSHMFDGMF---IPKARPADKWKHEIASVQMFDHLVEVNGLEAVMLHHGMRLPEDLIFIKEQIAGPLESAVLDQSQWPYKGRPVEKSFLYEVVANKRNGIDVDKWDYFARDCYHLGIQNN---FDYQRFLRFARVC--EVKGRKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITEAF--LKADPHIQ---IQGSSGRIFTISSAIEDMEAY-SKLTDHIFEQILYSSGPELSEARAILQNIICRRLYKCVGQTTSETNV-DVSQEKLLDWAKELARS-KPTGTEGNLIAEDFVVSVIHMDYGMKEKNPINNVHFYCKNDPTKAIKIHKKQVSKLLPERFAEQLIRVYCKKT 536
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Zebrafish
Match: si:ch73-236c18.9 (si:ch73-236c18.9 [Source:ZFIN;Acc:ZDB-GENE-121214-125]) HSP 1 Score: 166.007 bits (419), Expect = 4.783e-45 Identity = 141/458 (30.79%), Postives = 215/458 (46.94%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWE-------------KAFDDSIP-TRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKY---NE-KIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL----KTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVENKLNDVT--GNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKG-NPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+I DT +FQRLR +KQLG VYP +S++RFEHSIG +LA L K L D E +T+ D C++IA LCHDLGHG SH ++ K D IP + HE++SV +F S++ S N + E L + + I +I G NE G+ K +L+EIVANK++G+DVDK+DY RD + G N D R+L F RV +NG + RD+E +++D+F+TR LHR Y+HK +E +F AL + + E+ I+ + + DYS + D +S +P DI+ +I R L K R+ K+ + N W+ + K K +++ + + + L K NP+ V FY+K P + L + +E ++ ++ S
Sbjct: 78 VKITDTPQFQRLRHLKQLGGTYLVYPGASHNRFEHSIGVAYLAGRLVKSLH--------DNQPELKITKQDFLCVQIAGLCHDLGHGPLSHVFDALVIPEAKKIKTRKGLPDDIPESWKHEQMSVLMFDSIVKS----LNEEVLREHGLTDNDVIFIKELIEGAKASDNEWPYKGRNVEKSFLYEIVANKQNGIDVDKWDYFARDCHHLGIRNS---FDHLRLLKFARVC--VVNGRKHICFRDKEADNVYDMFRTRYTLHRQAYQHKIGNIIEDMFAEALLLADRDLHEDRPADMLKISEAIKSVEDYS-----------KLTDEIFEQILSSTSPNLKESRDILDKIMRRKLPKFIGETRLTKKIKSMEELKNSWKAAIEK-YKPTDPNVNLTTEELPVYVVDLDHGMKDKNPIEHVYFYSKRKPNEASTIEDYQLSSFLPNKFNEELVRVYYRGS 506
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Match: SAMHD1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:100498574]) HSP 1 Score: 176.407 bits (446), Expect = 1.558e-48 Identity = 135/447 (30.20%), Postives = 215/447 (48.10%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDD-SIPTR--PHEELSVEIFKSLLNSS---------KLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGN--RLDYSSDIWFSRGFINRAVDHHLWDTMS---RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT EFQRLR +KQLG YV+P +S++RFEHSIG +LA L + L ++ E + DM C++IA LCHDLGHG +SH ++ F + P R HE SV +F L+ S+ LC + F + E+ + ++N +K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E+ + RD+E+ +++D+F TRN LHR Y+HK +E + A I +P R I GN + S D + + + HH+ + + + +I+ ++E R L K + +N + L D+ + + S ++ + F + + NP+ +V+FY K +PR + + L+ E I+ ++ +K+
Sbjct: 44 VRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALH--------ERQPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASVAMFDHLIKSNGLEEVMKEYGLCLPDDLTF---IKEQIAGPLSSEDEQQFNSSRTEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFLKFARVC--EVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAF--IKADPHIR---IKGSDGNYYTISGSVDDMVAYTKLTDNIYHHILYSDNPDLKEAREILRKVERRQLYKFVG--QTHPSINSRIEPDEYDTLPADLAKSVPQTSTTDVELNTEDFIVDVIHMDYGMKEQNPINNVRFYCKSDPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKT 467
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Match: SAMHD1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:100498574]) HSP 1 Score: 172.94 bits (437), Expect = 7.354e-48 Identity = 137/452 (30.31%), Postives = 215/452 (47.57%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDD-SIPTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELD-EKSIDLIGRIIIGKYNEKIDG-------------KKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGN--RLDYSSDIWFSRGFINRAVDHHLWDTMS---RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT EFQRLR +KQLG YV+P +S++RFEHSIG +LA L + L ++ E + DM C++IA LCHDLGHG +SH ++ F + P R HE SV +F L+ S+ L + E L + I I G + + D +K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E+ + RD+E+ +++D+F TRN LHR Y+HK +E + A I +P R I GN + S D + + + HH+ + + + +I+ ++E R L K + +N + L D+ + + S ++ + F + + NP+ +V+FY K +PR + + L+ E I+ ++ +K+
Sbjct: 19 VRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALH--------ERQPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASVAMFDHLIKSNGL---EEVMKEYGLCLPDDLTFIKEQIAGPLSSEDDAASFSTWYIFCRTEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFLKFARVC--EVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAF--IKADPHIR---IKGSDGNYYTISGSVDDMVAYTKLTDNIYHHILYSDNPDLKEAREILRKVERRQLYKFVG--QTHPSINSRIEPDEYDTLPADLAKSVPQTSTTDVELNTEDFIVDVIHMDYGMKEQNPINNVRFYCKSDPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKT 447
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Match: SAMHD1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:100498574]) HSP 1 Score: 172.555 bits (436), Expect = 1.837e-47 Identity = 137/455 (30.11%), Postives = 215/455 (47.25%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDD-SIPTR--PHEELSVEIFKSLLNSS---------KLCYNRSIKFEIEL--------DEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGN--RLDYSSDIWFSRGFINRAVDHHLWDTMS---RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT EFQRLR +KQLG YV+P +S++RFEHSIG +LA L + L ++ E + DM C++IA LCHDLGHG +SH ++ F + P R HE SV +F L+ S+ LC + F E DE+ + + I +K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E+ + RD+E+ +++D+F TRN LHR Y+HK +E + A I +P R I GN + S D + + + HH+ + + + +I+ ++E R L K + +N + L D+ + + S ++ + F + + NP+ +V+FY K +PR + + L+ E I+ ++ +K+
Sbjct: 19 VRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALH--------ERQPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASVAMFDHLIKSNGLEEVMKEYGLCLPDDLTFIKEQIAGPLSSEDEQQFNSMDPIYKNWPYRGRTEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFLKFARVC--EVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAF--IKADPHIR---IKGSDGNYYTISGSVDDMVAYTKLTDNIYHHILYSDNPDLKEAREILRKVERRQLYKFVG--QTHPSINSRIEPDEYDTLPADLAKSVPQTSTTDVELNTEDFIVDVIHMDYGMKEQNPINNVRFYCKSDPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKT 453
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Match: SAMHD1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:100498574]) HSP 1 Score: 173.326 bits (438), Expect = 2.508e-47 Identity = 140/460 (30.43%), Postives = 218/460 (47.39%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDD-SIPTR--PHEELSVEIFKSLLNSS---------KLCYNRSIKF-------EIELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGN--RLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD------IVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT EFQRLR +KQLG YV+P +S++RFEHSIG +LA L + L ++ E + DM C++IA LCHDLGHG +SH ++ F + P R HE SV +F L+ S+ LC + F + +++ D++ I KY G+ K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E+ + RD+E+ +++D+F TRN LHR Y+HK +E + A I +P R I GN + S D + + + HH+ + PD I+ ++E R L K + +N + L D+ + + S ++ + F + + NP+ +V+FY K +PR + + L+ E I+ ++ +K+
Sbjct: 49 VRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALH--------ERQPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASVAMFDHLIKSNGLEEVMKEYGLCLPDDLTFIKEQIAGPLSSEDEQQDVLPPWI--KYKWPYRGRTEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFLKFARVC--EVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAF--IKADPHIR---IKGSDGNYYTISGSVDDMVAYTKLTDNIYHHI---LYSDNPDLKEAREILRKVERRQLYKFVG--QTHPSINSRIEPDEYDTLPADLAKSVPQTSTTDVELNTEDFIVDVIHMDYGMKEQNPINNVRFYCKSDPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKT 483
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Match: SAMHD1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:100498574]) HSP 1 Score: 172.94 bits (437), Expect = 3.854e-47 Identity = 138/446 (30.94%), Postives = 214/446 (47.98%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDD-SIPTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRII-----IGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGN--RLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD------IVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT EFQRLR +KQLG YV+P +S++RFEHSIG +LA L + L ++ E + DM C++IA LCHDLGHG +SH ++ F + P R HE SV +F L+ S+ L E + E + L + I Y + + +K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E+ + RD+E+ +++D+F TRN LHR Y+HK +E + A I +P R I GN + S D + + + HH+ + PD I+ ++E R L K + +N + L D+ + + S ++ + F + + NP+ +V+FY K +PR + + L+ E I+ ++ +K+
Sbjct: 67 VRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALH--------ERQPELQINHRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPKRKFKHESASVAMFDHLIKSNGL--------EEVMKEYGLCLPDDLTFIKEQIWPYRGRTE-EKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFLKFARVC--EVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAF--IKADPHIR---IKGSDGNYYTISGSVDDMVAYTKLTDNIYHHI---LYSDNPDLKEAREILRKVERRQLYKFVG--QTHPSINSRIEPDEYDTLPADLAKSVPQTSTTDVELNTEDFIVDVIHMDYGMKEQNPINNVRFYCKSDPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKT 480
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Mouse
Match: Samhd1 (SAM domain and HD domain, 1 [Source:MGI Symbol;Acc:MGI:1927468]) HSP 1 Score: 166.007 bits (419), Expect = 1.900e-44 Identity = 137/458 (29.91%), Postives = 219/458 (47.82%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDE---------LNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRK---ELRKDIXXXXXXXXXXXXDFSLSTFTLQ--SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ S+E+F+ L+NS++L +K + E+ I I I+G + K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F R+ E + + R++E+ +++D+F TRN LHR Y+HK ++ + A + +P IT G + S+ I F + D+ H D I+ IE R L K + K + E+ + E+ K + +++ DF + + E+K NP+ V FY K N + N+ + L+ E ++ ++ +K
Sbjct: 146 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRAL--------AEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPRARPEKKWKHEQGSIEMFEHLVNSNEL--KLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAF--LKADPYVE---ITGTAGKKFRISTAIDDMEAF-TKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLG--ETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDK-NPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKK 578
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Mouse
Match: Samhd1 (SAM domain and HD domain, 1 [Source:MGI Symbol;Acc:MGI:1927468]) HSP 1 Score: 166.392 bits (420), Expect = 2.044e-44 Identity = 137/458 (29.91%), Postives = 219/458 (47.82%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDE---------LNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRK---ELRKDIXXXXXXXXXXXXDFSLSTFTLQ--SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ S+E+F+ L+NS++L +K + E+ I I I+G + K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F R+ E + + R++E+ +++D+F TRN LHR Y+HK ++ + A + +P IT G + S+ I F + D+ H D I+ IE R L K + K + E+ + E+ K + +++ DF + + E+K NP+ V FY K N + N+ + L+ E ++ ++ +K
Sbjct: 166 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRAL--------AEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPRARPEKKWKHEQGSIEMFEHLVNSNEL--KLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAF--LKADPYVE---ITGTAGKKFRISTAIDDMEAF-TKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLG--ETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDK-NPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKK 598
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Mouse
Match: Samhd1 (SAM domain and HD domain, 1 [Source:MGI Symbol;Acc:MGI:1927468]) HSP 1 Score: 166.007 bits (419), Expect = 2.777e-44 Identity = 137/458 (29.91%), Postives = 219/458 (47.82%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDE---------LNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRK---ELRKDIXXXXXXXXXXXXDFSLSTFTLQ--SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ S+E+F+ L+NS++L +K + E+ I I I+G + K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F R+ E + + R++E+ +++D+F TRN LHR Y+HK ++ + A + +P IT G + S+ I F + D+ H D I+ IE R L K + K + E+ + E+ K + +++ DF + + E+K NP+ V FY K N + N+ + L+ E ++ ++ +K
Sbjct: 166 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRAL--------AEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPRARPEKKWKHEQGSIEMFEHLVNSNEL--KLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAF--LKADPYVE---ITGTAGKKFRISTAIDDMEAF-TKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLG--ETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDK-NPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKK 598
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Mouse
Match: Samhd1 (SAM domain and HD domain, 1 [Source:MGI Symbol;Acc:MGI:1927468]) HSP 1 Score: 162.54 bits (410), Expect = 2.231e-43 Identity = 134/439 (30.52%), Postives = 210/439 (47.84%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDE---------LNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRK---ELRKDIXXXXXXXXXXXXDFSLSTFTLQ--SENKGNPLLSVKFYTKENPRNCFNFNENSL 1226
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ S+E+F+ L+NS++L +K + E+ I I I+G + K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F R+ E + + R++E+ +++D+F TRN LHR Y+HK ++ + A + +P IT G + S+ I F + D+ H D I+ IE R L K + K + E+ + E+ K + +++ DF + + E+K NP+ V FY K N + N+ +
Sbjct: 166 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRAL--------AEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPRARPEKKWKHEQGSIEMFEHLVNSNEL--KLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAF--LKADPYVE---ITGTAGKKFRISTAIDDMEAF-TKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLG--ETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDK-NPIDRVHFYCKSNSKQAVRINKEQV 579
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Match: sp|Q9Y3Z3|SAMH1_HUMAN (Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2) HSP 1 Score: 174.096 bits (440), Expect = 1.722e-46 Identity = 138/452 (30.53%), Postives = 222/452 (49.12%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIE----LDEKSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVEN--KLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L L G+K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ IK +E + E+ I I I+G ++ K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F RV E++ R+ RD+E+ +++D+F TRN LHR Y+HK ++ + A ++ +Y + IT G + S+ I + + D+ + + P +I+ +IE R L K + K+ KE+ +L + +++ DF + + + NP+ V FY K P +N + L+ E ++ ++ +K
Sbjct: 133 VRIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVHAL--------GEKQPELQISERDVLCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEVKWTHEQGSVMMFEHLINSN------GIKPVMEQYGLIPEEDICFIKEQIVGPLESPVEDSLWPYKGRPENKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARVC--EVDNELRICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNIIDTMITDAF---LKADDYIE--ITGAGGKKYRISTAIDDMEAY-TKLTDNIFLEILYSTDPKLKDAREILKQIEYRNLFKYVGETQPTGQIKIKREDYESLPKEVASAKPKVLLDVKLKAEDFIVDVINMDYGMQEKNPIDHVSFYCKTAPNRAIRITKNQVSQLLPEKFAEQLIRVYCKK 556
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Match: sp|Q5ZJL9|SAMH1_CHICK (Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Gallus gallus OX=9031 GN=SAMHD1 PE=2 SV=2) HSP 1 Score: 173.711 bits (439), Expect = 2.143e-46 Identity = 133/457 (29.10%), Postives = 223/457 (48.80%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR------PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTI-----VENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTP------DIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSEN------KGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT +FQRLR +KQLG +V+P +S++RFEHS+G +LA L + L+ ++ E +T+ D+ C+EIA LCHDLGHG +SH ++ F IP HE SVE+F+ L+ S+KL ++ + E+ I I I G +E +K +L+EIVANK++G+DVDK+DY RD + G N D +R++ F RV E + RD+E+ +++D+F TRN LHR Y+HK +E + A + +E + + I+ M + Y+ + D+ + + P +I+ +IE R L K + E K+N++ +E+ L DI + + ++ + F + N NP+ +V FY K +P ++ + L+ E ++ ++ ++
Sbjct: 124 VRIIDTPQFQRLRYIKQLGGTYFVFPGASHNRFEHSLGVGYLAGCLVRELK--------ERQPELDITQRDILCVEIAGLCHDLGHGPFSHMFDGRF---IPLARQGLNWKHETASVEMFEHLITSNKL--EEIMESYGLILEEDIAFIKEQIGGPIDETACEESWPYRGRPKEKSFLYEIVANKKNGIDVDKWDYFARDCHHLGIQNN---FDYRRLIKFTRVC--EAGNQKHICARDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIEIMITEAFQKADCFFQIEGSKGKLYHISTAMEDMEAYT-----------KLTDNIYLEILHSSRPELSEAREILHKIERRELYKFLGETQPE-KVNEIPKDEY-DGLAGDIANSKPEKDPPDVELTAEDFIVDVVNMDYGMKDQNPIDNVLFYCKADPSKAIKISKEQVSRLLPGTFSEQVIRVYCKRQ 549
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Match: sp|Q0VCA5|SAMH1_BOVIN (Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Bos taurus OX=9913 GN=SAMHD1 PE=2 SV=1) HSP 1 Score: 171.4 bits (433), Expect = 1.190e-45 Identity = 141/457 (30.85%), Postives = 226/457 (49.45%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI-----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD------IVARIEERCLLK-------LFSRFRVENK---LNDVTGNEWRK-ELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV +F+ L+NS+ L +K+ + E+ I I I G I +K +L+EIVANK +G+DVDK+DY RD + G N D KR L F RV E++ + R++E+ +++D+F TRN LHR Y+HK ++ + A ++ E IT G + S+ I F + D+ + + P+ I+ +IE R L K + R + EN N+V + EL ++K+ + + ++D+ + E+K NP+ V+FY K + N + + E ++ ++ +K+
Sbjct: 122 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGRLVREL--------SEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPLARPEIKWTHEQGSVMMFEHLINSNGL--QDVMKYYGLIPEEDILFIKEQITGPPESPIKDASKWLYKGRPKEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNS---FDYKRFLKFARVC--EVDNMKHICTREKEVGNLYDMFHTRNCLHRRAYQHKVGNIIDTMITDAFLKADDHIE-----ITGSAGRKYHISTAIDDMEAF-TKLTDNIFLEILYSTDPNLNDARMILKKIESRNLYKFVGETQPMIQRIKKENYEHLPNEVASAKPSDVELEAELKAEDLIVDVINMDYGM-------EDK-NPIDHVRFYCKSDLSKAVMITRNQVSQFLPETFAEQLIRVYCKKT 546
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Match: sp|Q502K2|SAMH1_DANRE (Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Danio rerio OX=7955 GN=samhd1 PE=2 SV=2) HSP 1 Score: 169.088 bits (427), Expect = 1.106e-44 Identity = 133/447 (29.75%), Postives = 219/447 (48.99%), Query Frame = 3
Query: 24 IDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKL---CYNRSIKFE---IELDEKSIDLIGRIIIGKYNEKIDGK---KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD----------IVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENK-GNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
IDT +FQRLR +KQLG V+P +S++RFEHSIG +LA L K L ++ E +T+ D+ C++IA LCHDLGHG +SH ++ F IP RP HE SV++F L+ + L + ++ I + E+ + ++ + G+ K +L+E+VANK +G+DVDK+DY RD + G N D +R L F RV E+ G + RD+E+ +++D+F TRN LHR Y+HK +E + A + +P + I G SS I + ++ DH + P+ I+ R +C+ + S V+ + +W KEL + K ++ ++ + DF +S + K NP+ +V FY K +P ++ + L+ E ++ ++ +K+
Sbjct: 115 IDTPQFQRLRHIKQLGGTYLVFPGASHNRFEHSIGVGYLAGCLVKAL--------NERQPELFITKQDILCVQIAGLCHDLGHGPFSHMFDGMF---IPKARPADKWKHEIASVQMFDHLVEVNGLEAVMLHHGMRLPEDLIFIKEQIAGPLESAVLDQSQWPYKGRPVEKSFLYEVVANKRNGIDVDKWDYFARDCYHLGIQNN---FDYQRFLRFARVC--EVKGRKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITEAF--LKADPHIQ---IQGSSGRIFTISSAIEDMEAY-SKLTDHIFEQILYSSGPELSEARAILQNIICRRLYKCVGQTTSETNVDVSQEKLL--DWAKELARS-KPTGTEGNLIAEDFVVSVIHMDYGMKEKNPINNVHFYCKNDPTKAIKIHKKQVSKLLPERFAEQLIRVYCKKT 536
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Match: sp|Q60710|SAMH1_MOUSE (Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Mus musculus OX=10090 GN=Samhd1 PE=1 SV=3) HSP 1 Score: 166.007 bits (419), Expect = 1.942e-43 Identity = 137/458 (29.91%), Postives = 219/458 (47.82%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI----------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDE---------LNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRK---ELRKDIXXXXXXXXXXXXDFSLSTFTLQ--SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
+IIDT +FQRLR +KQLG YV+P +S++RFEHS+G +LA L + L +K E ++E D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ S+E+F+ L+NS++L +K + E+ I I I+G + K +L+EIV+NK +G+DVDK+DY RD + G N D KR + F R+ E + + R++E+ +++D+F TRN LHR Y+HK ++ + A + +P IT G + S+ I F + D+ H D I+ IE R L K + K + E+ + E+ K + +++ DF + + E+K NP+ V FY K N + N+ + L+ E ++ ++ +K
Sbjct: 166 RIIDTPQFQRLRYIKQLGGGYYVFPGASHNRFEHSLGVGYLAGCLVRAL--------AEKQPELQISERDILCVQIAGLCHDLGHGPFSHMFDGRF---IPRARPEKKWKHEQGSIEMFEHLVNSNEL--KLVMKNYGLVPEEDITFIKEQIMGPPITPVKDSLWPYKGRPATKSFLYEIVSNKRNGIDVDKWDYFARDCHHLGIQNN---FDYKRFIKFARICEVEYKVKEDKTYIRKVKHICSREKEVGNLYDMFHTRNCLHRRAYQHKISNLIDIMITDAF--LKADPYVE---ITGTAGKKFRISTAIDDMEAF-TKLTDNIFLEVLHSTDPQLSEAQSILRNIECRNLYKYLG--ETQPKREKIRKEEYERLPQEVAKAKPEKAPDVELKAEDFIVDVINVDYGMEDK-NPIDRVHFYCKSNSKQAVRINKEQVSQLLPEKFAEQLIRVYCKK 598
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Match: A0A372RM43 (HD domain-containing protein OS=Rhizophagus sp. MUCL 43196 OX=1803374 GN=C1646_685220 PE=4 SV=1) HSP 1 Score: 193.356 bits (490), Expect = 2.789e-52 Identity = 139/439 (31.66%), Postives = 221/439 (50.34%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL----------KTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRV----ENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPR-NCFNFNENSLPDLVKLISDETILMIFA 1277
+ IDT+ FQRLR +KQLG YVYP +S++RFEH +G +LA+ L K +R + D C ++ D+KC+ +AALCHDLGHG +SH +E+ P R HEE S+ +F LL K + + D+K I +I GK E + YLF++VANK + +DVDKFDYL RD Y G + + D R++++ RV +D++ ++ +E ++I+++F TR LH+ Y H+ K+++ + AL K+I + EY + + + NR++YS + +++ DI+ RI +R L K F V + KL D GN + ++ K I L ++ + TL + + NP+ +VKFY K P F + + LV + +E + IF
Sbjct: 30 VKFIDTEHFQRLRSIKQLGTTYYVYPGASHNRFEHCLGVAYLANSLVKRIRE---TQHDDLKC----SDKDLKCVTLAALCHDLGHGPFSHLFEEFIKMRRPDRKWTHEEASIMMFDDLLKEHK-------EIAYDFDDKDKQFIKDLITGKKPEDTGNRSPYLFDVVANKRNSIDVDKFDYLARDCYYLGMKS---VFDFSRLMNYSRVSDDQITYDF------KESYNIYELFHTRYSLHKKAYNHRVGKAIDYMILDALEAADPFLEISKSIDKPSEYLK--MDDTILNRIEYSDNPNL------------------KKSKDIIRRIRKRDLYKFVDEFLVPKDLKRKLKDSKGNVEKDKITKTITDQLELDGIKKDYAIVDILTLNYGKKEENPIDNVKFYDKNQPNIKVFKLESSQVSYLVPELFEEINIRIFT 425
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Match: A0A3Q1HNY4 (HD domain-containing protein OS=Anabas testudineus OX=64144 PE=4 SV=1) HSP 1 Score: 192.2 bits (487), Expect = 2.299e-51 Identity = 143/473 (30.23%), Postives = 229/473 (48.41%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK------------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMS--RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENK-GNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLL 1388
+IIDT +FQRLR +KQLG +VYP +S++RFEHS+G +LA EL + L+ + D E ++ E D+ ++IA LCHDLGHG +SH +E P + HE++S+E+F L+ + L + + L + + I +I K +K DG K +L+EIVANK +G+DVDKFDY RD + G N D +R L F RV E +G + +RD+E+++++D F TR LHR Y+H+ K++E + K L + +D I L+ D+ + + L+ T + +I+ARI R L V + EW+K+L + + ++ DF + T+ K NP+ + FY K +P+ + + L+ ET + ++ KS+ +N K+ + LQ + S LL
Sbjct: 69 VKIIDTPQFQRLRYIKQLGGAYFVYPGASHNRFEHSLGVGYLAGELAQALKTK-----HDNEGENLIDEKDILSVQIAGLCHDLGHGPFSHMFESV----CPKKKHEQISIEMFDYLVEENGL---KPLMQLYGLSDPDLSFIKEMIDPKPRDK-DGNVSSWPHKGRGEDKSFLYEIVANKTNGVDVDKFDYFARDCHHLGMQNN---FDYRRFLKFARVCEAE-DGKKHICIRDKEVYNMYDFFHTRYCLHRRAYQHRVNKAIEIMIKDVLSKV------KDIKIEGFEKTLLESIDDMAAYTKLTDCLLQVILFSTDENLKEAKEILARICSRDLYVFLGETLVAE-----SKTEWKKKLAEPL-------RLKPEDFEIEQVTINYGMKEKNPIEKMNFYNKSDPQKAVPLPKEQVSHLLPDTFSETFIRVYCRKSLRRAEKTQLMNWCKENIFKTLQVIFTSSDTSFLL 506
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Match: A0A3Q1HLT1 (HD domain-containing protein OS=Anabas testudineus OX=64144 PE=4 SV=1) HSP 1 Score: 190.66 bits (483), Expect = 5.446e-51 Identity = 140/455 (30.77%), Postives = 230/455 (50.55%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKL-----CYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK-KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMS--RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKG-NPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQ 1352
+IIDT +FQRLR +KQLG +VYP +S++RFEHS+G +LA EL + L+ + D E ++ E D+ ++IA LCHDLGHG +SH +E F HE++S+E+F+ L+ ++L Y+ S + ++ ++ IDL R GK + G+ K +L+EIV+NK +G+DVDKFDY RD + G N D +R L F RV E +G + +RD+E+++++D F TR LHR Y+H+ K++E + K L + +D I L+ D+ + + L+ T + +I+ARI R L T EW+K+L + ++ +E + T+ K NP+ + FY K +P+ + + L+ ET + ++ +K++ D + N K+ + LQ
Sbjct: 59 VKIIDTPQFQRLRYIKQLGGAYFVYPGASHNRFEHSLGVGYLAGELAQALKTK-----HDNEGENLIDEKDILSVQIAGLCHDLGHGPFSHMFESVFS----VLQHEQISIEMFEHLVEENRLKPLMKLYDLSDR-DLHFIKEMIDLEPRGKDGKLRFEGRGEDKSFLYEIVSNKTNGVDVDKFDYFARDCHHLGMQNN---FDYRRFLKFARVCEAE-DGKKHICIRDKEVYNMYDFFHTRYCLHRRAYQHRVNKAIEIMIKDVLSKV------KDIKIEGFEKTLLESIDDMAAYTKLTDSLLQVILFSTDENLKEAKEILARICSRDLYVFLGE----------TLIEWKKKLAEPLRLKPEDFEIEVGSYLHLQVTINYGMKERNPIEKMNFYNKSDPQKAVPLPKEQVSHLLPDTFSETFIRVYCKKTLQPDERKRLENWCKENIFKTLQ 483
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Match: V3YXK1 (HD domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_61530 PE=4 SV=1) HSP 1 Score: 187.578 bits (475), Expect = 2.298e-50 Identity = 139/441 (31.52%), Postives = 224/441 (50.79%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEI-LTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSI-PTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI-DGK--KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLW--DTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKG-NPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDR 1307
+IIDT +FQRLR +KQLG C +VYP ++++RFEHSIG +LASE+ K L+ +L E+ +TE D C+ IA LCHDLGHG +SH ++ F + PT HE+ S+++ + ++ +KL E E+ + + I +I G K+ G+ K YL+EIVANK + +DVDK+DY RD G N D R + F RV+ DE G ++ +RD+E +++D+F TRN LHR Y+H ++E + A+ I+ N + M + + D+ + LW D + +++ R+++R L + +F T K+L ++I + +++S + L L K NPL +V+FY+K P + + L+ E I+ I+ + + D DR
Sbjct: 17 VKIIDTPQFQRLRYLKQLGACYFVYPGATHNRFEHSIGVSYLASEMVKRLK---------ELQPELKITEVDRLCVTIAGLCHDLGHGPFSHMYDNQFIPKVDPTTEWTHEKASIDMLEYMIEDNKLGGEFD---EYEITDIDLIFIKELIYGPLENKVLKGRPDKGYLYEIVANKRNSIDVDKWDYFARDCHMLGIKNN---FDHVRCMKFMRVIPDE-TGTQQICLRDKEDGNLYDMFHTRNALHRRAYQHAVTHAIESMIVEAM--IIANDVIKISGKDGKMCSLSECIDDVVAYTKLTDNIYQDILWSEDPKLMKARELLNRVQKRQLFRCIGQFTPPTTFEKGT----EKKLLEEIVIYDNDKNLKSENLVLKHVFLDYGMKDQNPLDNVRFYSKSKPNETKRVRKEQVSQLLPETFQEHIIRIYYKDQNVEDIDR 435
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Match: A0A3P9AYL8 (HD domain-containing protein OS=Maylandia zebra OX=106582 PE=4 SV=1) HSP 1 Score: 189.119 bits (479), Expect = 7.669e-50 Identity = 112/278 (40.29%), Postives = 169/278 (60.79%), Query Frame = 3
Query: 27 DTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDL--IGRIIIGKYNEKIDG---------KKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYR 824
DT +FQRLR +KQLG +VYP +S++RFEHSIG HLA EL K L+V+ L E + + D+ C++IA LCHDLGHG +SHF++ F D+I + HE+ S+E+FK LL+ + L K+ +++DE DL I +I ++K KK +L+EIV+NK++G+DVDKFDYL RD + G N D +R + F RV ++NG + RD+E +++DIF+ R +HR +HK +VE + K AL + ++P+++
Sbjct: 23 DTPQFQRLRNIKQLGGIYFVYPGASHNRFEHSIGVAHLAGELAKALKVKQL---------EQINDQDVLCVQIAGLCHDLGHGPFSHFFDGMFMDAIKRDKKHEKASIEMFKHLLDQNGL-KEVMKKYGLKVDEDGTDLVFIEEMIEKPQDKKPQNDWPYKGREEKKSFLYEIVSNKKTGIDVDKFDYLARDCHHLGIPNS---FDHQRFVMFARVC--DVNGRKHICSRDKESANLYDIFQQRLSIHRRACQHKIKMAVEIMLKDALILVDDHPDFK 285
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Match: ENSAMXT00000032130.1 (deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like [Source:NCBI gene;Acc:103028826]) HSP 1 Score: 185.652 bits (470), Expect = 2.915e-51 Identity = 140/435 (32.18%), Postives = 221/435 (50.80%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLL--NSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI-------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFS--RFRVENKLNDVTGNEWRKELR---KDIXXXXXXXXXXXXDFSLSTFTLQSENKG-NPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIF 1274
+IIDT EFQRLR +KQLG YVYP +S++RFEHS+G HLA +L + L+ L +T ND C++IAALCHDLGHG +SH ++ + HE+ SV++FK L+ N K R K EK I +I G D KK +L++IVAN +G+DVDK DY RD + G N H+ R + F RV ++ NG ++ MRD+E +++++F RNLLH Y+H+ VK+VE + ALK E +D N+ +D + ++ + + + ++ + + I+ R+ +R L KL F + + + EW+K L ++I++ + + DF+ K NP+ S++FY K +P +++ + L+ ET +M+F
Sbjct: 41 VKIIDTPEFQRLRNIKQLGGGYYVYPGASHNRFEHSLGVAHLAGKLLQSLKKTLPEGLE-------ITPNDELCVQIAALCHDLGHGPFSHAFDIFMKKLDSSWKHEDASVKMFKHLIEENGIKEIMARENKDWDAFSEKDFMFIMELIQGPSKSASEWPYKGRDKKKAFLYDIVANHRNGIDVDKMDYFTRDCHHLGMKC-NFSHE--RFITFARVCDE--NGETQICMRDKEAMNMYELFHVRNLLHHNAYQHRVVKAVELMIMDALK------EAKDHL--NLKEATMDPKTFVYLTDDILQKILNKP--EKKLEKAQKIIKRVLKRDLYKLLGVKTFEPQELKHLDSDEEWKKVLETWLENIQTPVGARKLNPEDFTEVQVKFNYGMKDKNPIDSLRFYRKYDPNTPIKLSKDEVSHLLPEKFAETKVMLF 453
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Match: ENSAMXT00000041115.1 (deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like [Source:NCBI gene;Acc:111197473]) HSP 1 Score: 168.318 bits (425), Expect = 4.579e-47 Identity = 107/266 (40.23%), Postives = 150/266 (56.39%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLL--NSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI---DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALK 797
+IIDT EFQR R +KQLG YVYP +S++RFEHS+G HLA +L + L+ L +T ND C++IAALCHDLGHG +SH ++ D HE+ S+E+F L+ N K K E+ I ++I G E+ + KK +L++IVAN +G+DVDK DY RD + G N H+ R + F RV E NG ++ MRD+E ++++IF RNLLH +H+ VK+VE + ALK
Sbjct: 29 VKIIDTPEFQRSRNIKQLGGVYYVYPGASHNRFEHSLGVAHLAGKLLQSLKKNLPEGLE-------ITPNDELCVQIAALCHDLGHGPFSHAFDIFMKDFDSKWKHEDASIEMFDHLIQKNGIKKIMEEENKDWDAFSEEHFMFIKKLIRGTKTEQPNEEEKKKAFLYDIVANYRNGIDVDKMDYFTRDCHHLGMKC-NFSHE--RFITFARVC--EENGETQICMRDKEAMNMYEIFHVRNLLHHNACQHRVVKAVELMIMDALK 282
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Match: ENSAMXT00000045292.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000081.1:2518931:2530795:1 gene:ENSAMXG00000031001.1 transcript:ENSAMXT00000045292.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 159.844 bits (403), Expect = 3.355e-43 Identity = 125/446 (28.03%), Postives = 214/446 (47.98%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI-------------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSR--FRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
IIDT +FQRLR +KQLG +V+P +S++RFEHSIG HLA +L + LR ++ +T+ D C++IA LCHDLGHG +SH +E + P HEE+SV +F L+ + + + ++ E ++ I +I +K YL++IV N+ +G+DVDK DY RD + G N H+ R L F RV DE G ++ +RD+E +++++F R+ LH Y H+ K+VE + AL+ E ++ D S+ + + + + +D L D P I+ RI +R + K FR + + W ++L+ ++ + +K L+F+ F + N+ +P+ ++FY ++ P + + + L+ E +M+F ++
Sbjct: 27 VSIIDTPQFQRLRNIKQLGGGYFVFPGASHNRFEHSIGVAHLAGKLVQSLRTDNELN---------ITDTDELCVKIAGLCHDLGHGPFSHVFEGFMKEENPESNWKHEEMSVRMFDYLIEENGI--SEIMRNEYNFTDQDFQFIRELIYTPKPPNNPNPENRQWSYTGRPQEKSYLYQIVNNQTTGIDVDKMDYFSRDCHHLGIKC-NFSHE--RYLVFARVCIDEELGT-QICIRDKEAMNMYELFHIRSYLHHNIYHHRVTKAVESMIVDALRAANER--------LSISAAVNDPSAYMKLTDFILQKILD--LADPEHPAAPGIIERISKREVYKFIDGKVFRPNDVRHVDLAESWEEKLQAWVEHVRNKAGGHQLEFNAQDFKIMPIKINCGRNEDDPISFLRFYRRDEPNIPIQLSRDEISFLLPERFAEIKVMVFYKR 447
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Match: ENSAMXT00000040847.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000081.1:2469780:2530795:1 gene:ENSAMXG00000031001.1 transcript:ENSAMXT00000040847.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 159.844 bits (403), Expect = 3.355e-43 Identity = 125/446 (28.03%), Postives = 214/446 (47.98%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR--PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKI-------------DGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSR--FRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQ------SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEK 1283
IIDT +FQRLR +KQLG +V+P +S++RFEHSIG HLA +L + LR ++ +T+ D C++IA LCHDLGHG +SH +E + P HEE+SV +F L+ + + + ++ E ++ I +I +K YL++IV N+ +G+DVDK DY RD + G N H+ R L F RV DE G ++ +RD+E +++++F R+ LH Y H+ K+VE + AL+ E ++ D S+ + + + + +D L D P I+ RI +R + K FR + + W ++L+ ++ + +K L+F+ F + N+ +P+ ++FY ++ P + + + L+ E +M+F ++
Sbjct: 27 VSIIDTPQFQRLRNIKQLGGGYFVFPGASHNRFEHSIGVAHLAGKLVQSLRTDNELN---------ITDTDELCVKIAGLCHDLGHGPFSHVFEGFMKEENPESNWKHEEMSVRMFDYLIEENGI--SEIMRNEYNFTDQDFQFIRELIYTPKPPNNPNPENRQWSYTGRPQEKSYLYQIVNNQTTGIDVDKMDYFSRDCHHLGIKC-NFSHE--RYLVFARVCIDEELGT-QICIRDKEAMNMYELFHIRSYLHHNIYHHRVTKAVESMIVDALRAANER--------LSISAAVNDPSAYMKLTDFILQKILD--LADPEHPAAPGIIERISKREVYKFIDGKVFRPNDVRHVDLAESWEEKLQAWVEHVRNKAGGHQLEFNAQDFKIMPIKINCGRNEDDPISFLRFYRRDEPNIPIQLSRDEISFLLPERFAEIKVMVFYKR 447
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Match: ENSAMXT00000057570.1 (deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like [Source:NCBI gene;Acc:111191578]) HSP 1 Score: 158.688 bits (400), Expect = 5.679e-42 Identity = 144/462 (31.17%), Postives = 219/462 (47.40%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRP------HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKID-------GKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFIT-----NVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLK-----LFSRFRV-------ENK----------LNDVTGNEWRKELRKDI--XXXXXXXXXXXXDFSLSTFTLQ-SENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIF 1274
+IIDT EFQRLR VKQ G YVYP +S++RFEHS+G HLA +L VQ L D L + + D C++IA LCHDLGHG +SH AFDD + HE+ SV++F L+ + K+ L + + I +I + K + +K +L+EIVANK +G+DVDK DY RD + G ++ N H+ R + F RV DE NG + MRD+E +++++F RNL+ + H+ K+VE + AL + + +E +T N + + DI I R+ D +L +++ +I+ RI +R L + LF R V E K N T ++ KD K + DF + L + NP+ S+ FY K P + ++ + ++ ET +M+F
Sbjct: 30 KIIDTPEFQRLRNVKQFGGGYYVYPGASHNRFEHSLGVAHLAGKL-----VQNLKDSQPDLG---IDDEDELCVQIAGLCHDLGHGPFSH----AFDDFMEQVQEDDKWKHEDQSVKMFDHLIIKGHIKGIMEKKY--NLKNEDFEFIKELINPDKDNKTEWQFKGRTQEKSFLYEIVANKLTGIDVDKMDYFSRDCHHLGMTS-NFSHE--RYMMFARVCTDE-NGEKHICMRDKEAVNMYELFHVRNLIRQRACHHRVAKAVELMITDALIEANSHFKLGEENLTICEAVNDLDTFTHLTDDILQE---IERSTDDNL-----KQSQEIIKRIRDRDLYRFVDGELFKRNEVRSLKTTKEKKDLLEKWIKKITNQQTNLSSEEQQLKDFLDKKNNQHPKLSPEDFRIVVIDLTYGMEESNPIDSLLFYKKNQPDKSYKLSKAKVSHMLPGTFAETRVMLF 465
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Sea Lamprey
Match: samhd1 (SAM domain and HD domain 1 [Source:NCBI gene;Acc:553453]) HSP 1 Score: 165.622 bits (418), Expect = 5.089e-46 Identity = 102/276 (36.96%), Postives = 156/276 (56.52%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK---------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWR-LAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
+IIDT +FQRLR +KQLG +V+P +S++RFEHS+G +LA +L ++ + E + E D+ C++IA LCHDLGHG +SH ++ +F IP RP HE SV++F L+ ++ L S ++ ++L E +D I I G + D K K +L+EIVANK +G+DVDK+DY RD + G N D +R + F RV E + + R++E+ +++D+F TRN LHR Y+H+ +E + K A
Sbjct: 76 VRIIDTPQFQRLRNIKQLGGTYWVFPGASHNRFEHSMGVGYLAGQLATAIQ--------SRQPELGINERDVLCVQIAGLCHDLGHGPFSHMFDNSF---IPAARPGCKWKHEVASVQMFDHLVQANGLEEVLSKEYGLKLPE-DLDFIKEQIAGPLADIADSKWPYKGRTKDKGFLYEIVANKSNGIDVDKWDYFARDCHHLGIQNN---FDHRRFIEFVRVCEVENERTKKVICFRNKEVGNLYDMFHTRNCLHRRAYQHRVGNIIELMIKEAF 336
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008965.1 (pep scaffold:Pmarinus_7.0:GL476766:34734:72987:-1 gene:ENSPMAG00000008111.1 transcript:ENSPMAT00000008965.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 144.05 bits (362), Expect = 3.732e-39 Identity = 99/268 (36.94%), Postives = 140/268 (52.24%), Query Frame = 3
Query: 21 IIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLC--EEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKL---CYNRSIKFEIELDEKSIDLIGRIIIGK------------YNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVE 773
I+DT EFQRLR +KQLG+C VYP + ++RFEH IGT HLA +L + L K C E +T+ D+ C+EIA LCHDLGHG +SH +E HE SVE+ L+ + L N ++F L LI +I+ Y EK K +LFEIVAN + +DVDKFDY RD Y G+ N + +R + RV E +G++ + ++ ++ ++F R LHR Y+H+ K +E
Sbjct: 20 IVDTPEFQRLRFIKQLGLCHKVYPSAVHTRFEHCIGTSHLAGQLVRHL----------KECSKEHNITDMDVLCVEIAGLCHDLGHGPFSHAFETVMKKKGIEWKHELKSVEMLCHLIEKNSLQKDLENCGLQFPHHL-----ILIASLIVAPKAGPLSSATEWLYIEKEYKCKMFLFEIVANDLNCIDVDKFDYFARDAYYLGF---NTGFEHQRYIQNARVC--EFHGDFHICQPKKQWSNLLELFHVRERLHRNAYQHRVTKLIE 267
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008964.1 (pep scaffold:Pmarinus_7.0:GL476766:34701:72987:-1 gene:ENSPMAG00000008111.1 transcript:ENSPMAT00000008964.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 142.51 bits (358), Expect = 1.279e-38 Identity = 100/276 (36.23%), Postives = 143/276 (51.81%), Query Frame = 3
Query: 21 IIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLC--EEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKL---CYNRSIKFEIELDEKSIDLIGRIIIGKYN------------EKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALK 797
I+DT EFQRLR +KQLG+C VYP + ++RFEH IGT HLA +L + L K C E +T+ D+ C+EIA LCHDLGHG +SH +E HE SVE+ L+ + L N ++F L I + I+ G + EK K +LFEIVAN + +DVDKFDY RD Y G+ N + +R + RV E +G++ + ++ ++ ++F R LHR Y+H+ K +E A+K
Sbjct: 20 IVDTPEFQRLRFIKQLGLCHKVYPSAVHTRFEHCIGTSHLAGQLVRHL----------KECSKEHNITDMDVLCVEIAGLCHDLGHGPFSHAFETVMKKKGIEWKHELKSVEMLCHLIEKNSLQKDLENCGLQFPHHL----ILIASLIVAGPLSSATCKIYFWYKIEKEYKCKMFLFEIVANDLNCIDVDKFDYFARDAYYLGF---NTGFEHQRYIQNARVC--EFHGDFHICQPKKQWSNLLELFHVRERLHRNAYQHRVTKLIEHKVAEAIK 276
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008967.1 (pep scaffold:Pmarinus_7.0:GL476766:55761:72987:-1 gene:ENSPMAG00000008111.1 transcript:ENSPMAT00000008967.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 121.324 bits (303), Expect = 1.595e-32 Identity = 77/184 (41.85%), Postives = 106/184 (57.61%), Query Frame = 3
Query: 21 IIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLC--EEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIE-LDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCR 563
I+DT EFQRLR +KQLG+C VYP + ++RFEH IGT HLA +L + L K C E +T+ D+ C+EIA LCHDLGHG +SH +E HE SVE+ L+ + S++ ++E L + L+ + + + EK K +LFEIVAN + +DVDKFDY R
Sbjct: 20 IVDTPEFQRLRFIKQLGLCHKVYPSAVHTRFEHCIGTSHLAGQLVRHL----------KECSKEHNITDMDVLCVEIAGLCHDLGHGPFSHAFETVMKKKGIEWKHELKSVEMLCHLIEKN------SLQKDLENLKTITFLLLSKTTLTEIIEKEYKCKMFLFEIVANDLNCIDVDKFDYFAR 187
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Nematostella
Match: EDO35455 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH5]) HSP 1 Score: 172.17 bits (435), Expect = 2.814e-47 Identity = 138/453 (30.46%), Postives = 224/453 (49.45%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLCYNRSIKF-EIELDEKSIDLIGRIIIGKYNEKIDGK------------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDH------HLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKE----LRKDIXXXXXXXXXXXXDFSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT +FQRLR +KQLG C +V+P ++++RFEHSIGT HLA EL + +R Q E +T D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV++F L++ +KL S +F L +K ++ I +I G N + K K YL+EIVANK +G+DVDK+DY RD G N D KR + RV+ ++ ++ +RD+E +I+D+F TR L + Y+HKT +E + A ++ G L S I + + DH H D ++ +I+ IE+R L K + ++ + + + R+E + D+ + + + L +F +++ NP+ ++FY+K+N F F + + ++ E + ++ K
Sbjct: 139 VKIIDTPQFQRLRNLKQLGGCYFVFPGAAHNRFEHSIGTSHLAGELLESIREQ--------QPELGITYVDVLCVKIAGLCHDLGHGPFSHMFDAGF---IPAARPGCDWKHEQASVDMFNYLVDDNKL----SEEFRRYGLSDKDMEFIQELIAGPRNMETPLKTQDWPYTGRSVEKSYLYEIVANKRTGIDVDKWDYFARDCHNLGIRNS---FDHKRFMKLARVI--KVGKRQQICIRDKEAGNIYDMFHTRTSLFKRAYQHKTANIIETMITEAFLKADKH-----LLFPGKNGKMLKMSEAIDDMVAYC-KLSDHVFYQILHSTDPQLQKAREILQCIEKRDLYKCVGQTIMKQRRDKEEIPDIRREIIDAIPPDVLGGGRAIDSDDVIIHLISFDYGMKDR-NPIDELRFYSKDNLSEAFVFRKELVSSMLPETFREQHMRVYCRKG 564
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Nematostella
Match: EDO35454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH4]) HSP 1 Score: 169.088 bits (427), Expect = 5.826e-47 Identity = 134/434 (30.88%), Postives = 215/434 (49.54%), Query Frame = 3
Query: 15 TQIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIP-TRP-----HEELSVEIFKSLLNSSKLC--YNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGK------------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPD------IVARIEER----CLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSL 1226
+IIDT +FQRLR +KQLG C +V+P ++++RFEHSIGT HLA L K +R + +T+ D+ C++IA LCHDLGHG +SH ++ F IP RP HE+ SV++F L++ +KL + R L +K ++ I +I G N + K K YL+EIVANK +G+DVDK+DY RD G N D KR + RV+ ++ ++ +RD+E +I+D+F TR L + Y+HKT +E + A ++ G L S I + + DH + + P I+ IE+R C+ + + R + ++ D+ E + DI ++ + + + L +F +++ NP+ ++FYTK+N F F + +
Sbjct: 88 VKIIDTPQFQRLRNLKQLGGCYFVFPGAAHNRFEHSIGTSHLAGGLLKSIR--------KRQPGLGITDVDVLCVKIAGLCHDLGHGPFSHMFDAGF---IPAARPGCDWKHEQASVDMFNYLVDDNKLLEEFRR-----YGLSDKDMEFIQELIAGPRNMETPLKTQDWPYTGRSIEKSYLYEIVANKRTGIDVDKWDYFARDCHNLGIRNS---FDHKRFMKLARVI--KVGKRQQICIRDKEAGNIYDMFHTRTSLFKRAYQHKTANIIETMITEAFLKADKH-----LLFPGKNGKMLKMSEAIDDMVAYC-KLSDHVFYQILHSTDPQLQEARRILQCIEKRDLYKCVGQTIMKQRRDKEIPDIR-KEIIDAIPPDILAVGRAIDSDDVIIHLISFDYGMKDR-NPIDELRFYTKDNLSEAFVFRKEQV 492
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Nematostella
Match: EDO26257 (pep supercontig:ASM20922v1:NEMVEscaffold_7765:3208:3433:-1 gene:NEMVEDRAFT_v1g154803 transcript:EDO26257 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 56.9954 bits (136), Expect = 6.484e-11 Identity = 23/37 (62.16%), Postives = 32/37 (86.49%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIG 128
+IIDT +FQRLR +KQLG C +V+P ++++RFEHSIG
Sbjct: 19 KIIDTPQFQRLRNLKQLGGCYFVFPGAAHNRFEHSIG 55
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Medaka
Match: samhd1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:NCBI gene;Acc:101159989]) HSP 1 Score: 174.866 bits (442), Expect = 6.762e-48 Identity = 131/449 (29.18%), Postives = 217/449 (48.33%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR------PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDE------KSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMS--RRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXX-XXXDFSLSTFTLQSENK-GNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT +FQRLR +KQLG +V+P +S++RFEHSIG +LA +L + L ++ E ++ D+ C++IA LCHDLGHG +SH ++ F IP HE S+++F L+ S+ L ++ ++E + +D I I G + + G+ K +L+EIVANK +G+DVDK+DY RD + G N D +R L F RV E++G + RD+E+ +++D+F TRN LHR Y+HK +E + A + +P + E M D+ + + L + S R +I+ I R L K + + + + W +EL + S + DF ++ + K NP+ +V+FY K +P +N + L+ E ++ ++ +K+
Sbjct: 97 KIIDTPQFQRLRNIKQLGGTYFVFPGASHNRFEHSIGVGYLAGQLVQAL--------NERQPELLICHRDILCVQIAGLCHDLGHGPFSHMFDGMF---IPKACPQVNWKHETASLDMFDHLVESNGL--------KVVMEEHGLVLPEDLDFIKEQIAGPLSTQTPGQKWPYKGRPEDKSFLYEIVANKRNGIDVDKWDYFARDCYHLGIQNN---FDYQRFLKFARVC--EVDGQKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVCNIIETMITEAF--LKADPYIQIEGTEGKMFTLSTAIDDMVAYTKLTDYVFEQILNSSSSELREAREILHNIVCRRLYKCLGQTQPDQTI-------WEQELSESTPQNSSSAVSLQPQDFIVNVIVMDYGMKEKNPINNVRFYCKNDPNKAIQIRKNQVSKLLPEHFAEQLIRVYFKKT 512
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Medaka
Match: samhd1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 [Source:NCBI gene;Acc:101159989]) HSP 1 Score: 175.252 bits (443), Expect = 6.872e-48 Identity = 129/467 (27.62%), Postives = 220/467 (47.11%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTR------PHEELSVEIFKSLLNSSKLCYNRSIKFEIELDE------KSIDLIGRIIIGKYNEKIDGK----------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTI-----VENPEYRDEFITNVMGNRLDY---------------SSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXX-XXXDFSLSTFTLQSENK-GNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKS 1286
+IIDT +FQRLR +KQLG +V+P +S++RFEHSIG +LA +L + L ++ E ++ D+ C++IA LCHDLGHG +SH ++ F IP HE S+++F L+ S+ L ++ ++E + +D I I G + + G+ K +L+EIVANK +G+DVDK+DY RD + G N D +R L F RV E++G + RD+E+ +++D+F TRN LHR Y+HK +E + A +E E + ++ + + + Y SS++ +R ++ V L+ + + PD + + + W +EL + S + DF ++ + K NP+ +V+FY K +P +N + L+ E ++ ++ +K+
Sbjct: 126 KIIDTPQFQRLRNIKQLGGTYFVFPGASHNRFEHSIGVGYLAGQLVQAL--------NERQPELLICHRDILCVQIAGLCHDLGHGPFSHMFDGMF---IPKACPQVNWKHETASLDMFDHLVESNGL--------KVVMEEHGLVLPEDLDFIKEQIAGPLSTQTPGQKWPYKGRPEDKSFLYEIVANKRNGIDVDKWDYFARDCYHLGIQNN---FDYQRFLKFARVC--EVDGQKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVCNIIETMITEAFLKADPYIQIEGTEGKMFTLSTAIDDMVAYTKLTDYVFEQILNSSSSELREAREILHNIVCRRLYKCLGQTQPDQTVTVSQETI------------------KIWEQELSESTPQNSSSAVSLQPQDFIVNVIVMDYGMKEKNPINNVRFYCKNDPNKAIQIRKNQVSKLLPEHFAEQLIRVYFKKT 550
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Medaka
Match: ENSORLT00000044675.1 (deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like [Source:NCBI gene;Acc:101162528]) HSP 1 Score: 86.6557 bits (213), Expect = 5.989e-18 Identity = 63/175 (36.00%), Postives = 94/175 (53.71%), Query Frame = 3
Query: 330 HEELSVEIFKSLLNSSKLCYNRSIKFEIE---LDEKSIDLIGRIIIGKYNEKIDGK---------------KRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWR--LAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRAL 794
HE+ SVE+F+ LL NR + E++ L++ + I +I+G+ +K K K +L+EIV+NK++G+DVDKFDY RD + G N D R F RV+ E N R + RD+E +++D+F TR+ LHR Y+HK K+VE + K AL
Sbjct: 31 HEDASVEMFQYLLEK-----NRELLTEMKNSRLEDNDLVFIKELILGEPLKKKSDKPEDPSDWPYEGRGEDKSFLYEIVSNKQNGIDVDKFDYFARDCHHLGLKNN---FDHMRYFKFTRVIGVEKNKLKRKHICSRDKEAGNLYDLFYTRDRLHRRAYQHKVTKNVEIMIKDAL 197
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Match: SMESG000079646.1 (SMESG000079646.1) HSP 1 Score: 880.552 bits (2274), Expect = 0.000e+0 Identity = 444/449 (98.89%), Postives = 446/449 (99.33%), Query Frame = 3
Query: 72 MCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLLGKYNFREINY 1418
MCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFI NVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSR TPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIKSLLSKLSMESLDFSLSTFTLQSENKG+PLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIF+EKSIISDPDRICLNEVKDKLCGKL PDGNDGEISNLLGKYNFREINY
Sbjct: 1 MCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFIANVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRCTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIKSLLSKLSMESLDFSLSTFTLQSENKGDPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFSEKSIISDPDRICLNEVKDKLCGKLPPDGNDGEISNLLGKYNFREINY 449
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Match: SMESG000079667.1 (SMESG000079667.1) HSP 1 Score: 458.759 bits (1179), Expect = 1.152e-158 Identity = 250/464 (53.88%), Postives = 318/464 (68.53%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFD-DSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLLGKYNFR 1406
+IID+ +FQRLR ++QLG +VY + YSRFEHSIGTFHLASEL K L+ Q D+ E +++ D+KC+EIAALCHDLGHG YSHFWE AFD ++I R HE+LSVEIF LL K + IK +I L + +IDLI RII+G ++++ID K+ +LFEIVANK SGLDVDKFDYLCRD IYFGWSNKNKIHDIKRILHF R+ + W LAMRDREIFHIHD+F R+LLHRYGY+HKTVK +EC+F AL IV N + R+E I V+G ++ Y IWFS FI++ D+H+W+ MS+ T IV RI+ER L K+F + ++E + N ++ D++ + SKL + F +S+F LQSEN+GNPLLSV FYTK+NP C N+ E SLPDLVKL DE +LMIF E + +R+ L +K LC EI L KY FR
Sbjct: 32 EIIDSPQFQRLRHIRQLGFGYFVYSSAGYSRFEHSIGTFHLASELIKQLKNQ-----TDQDKEIEISDEDVKCVEIAALCHDLGHGPYSHFWEHAFDNETIEPRKHEDLSVEIFSMLLEHIKSDETQKIKDKIGLKKNTIDLIKRIILGNFDKEIDKKRMFLFEIVANKCSGLDVDKFDYLCRDSIYFGWSNKNKIHDIKRILHFLRIAKK--SDMWHLAMRDREIFHIHDVFYYRHLLHRYGYQHKTVKIIECMFNDALNDIVHNEDARNELIETVIGPKV-YDPKIWFSSEFISKVCDYHIWNIMSKYTSGIVERIQERKLYKIFDQIQIE-----LNPNFQGQKGHIDLQEIKSKLKDFPIKFVISSFALQSENRGNPLLSVNFYTKQNPLKCTNYEEESLPDLVKLKGDEIVLMIFTETIPNKETERM-LRTLKANLCS--------NEIEGLREKYIFR 473
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Match: SMESG000079583.1 (SMESG000079583.1) HSP 1 Score: 441.81 bits (1135), Expect = 5.597e-152 Identity = 236/472 (50.00%), Postives = 320/472 (67.80%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFD-DSIPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXDFSL----STFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLLGKYNFREINY 1418
+IIDT +FQRLR ++QLG VYP + YSRFEHSIGTFHLASEL K L+ Q+ +K ++++++++KC+EIAALCHDLGHG +SH WE AFD +I R HE+LSVE+F LL K ++IK +I+L+ + I+ I ++I+G YN+ D +K + FEIVANK SGLDVDKFDYLCRD IY GWSNKNKIHDIKRILH R+ G W LAMRDREIFHIHD+F R+LLHRY Y+HKTVK +EC+FK AL IV N + R+E I V+G ++ Y IWFS FI++ D+H+W+ MS+ T IV +I+ER L K+F + +++ N G +L++ + + DFS+ S+F++ SENKGNPLLSV FY+KENP CFN+ +++LPDLVKL+ +ET+L I E + PD E K +L L + + +I++L KY F+ + Y
Sbjct: 28 EIIDTPQFQRLRHIRQLGFGYLVYPTAGYSRFEHSIGTFHLASELIKQLKSQI-----NKEKVDMISDDEVKCVEIAALCHDLGHGPFSHVWEHAFDSQTIQPRKHEDLSVEMFLRLLYHKKTGEIKNIKEKIKLNTEMINFIEKLILGTYNK--DEEKMFFFEIVANKTSGLDVDKFDYLCRDSIYLGWSNKNKIHDIKRILHLLRIAKKSDTGKWHLAMRDREIFHIHDVFYYRHLLHRYAYQHKTVKVIECMFKAALNDIVHNEDARNELIETVIGPKV-YDPKIWFSSDFISKVCDYHIWNIMSKYTSGIVEKIQERKLYKIFDQIQIKLDPN-FQGQNGHIDLQE--------IKSKLKDFSIKSVCSSFSVGSENKGNPLLSVNFYSKENPSECFNYTDDNLPDLVKLVENETVLTILTE----TKPDE----ETKKQL-KTLMDNLINRKIASLREKYTFKRMLY 473
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Match: SMESG000079633.1 (SMESG000079633.1) HSP 1 Score: 429.483 bits (1103), Expect = 4.486e-147 Identity = 227/472 (48.09%), Postives = 321/472 (68.01%), Query Frame = 3
Query: 21 IIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDS--IPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXD----FSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLLGKYNFREINY 1418
IIDT+EFQRLR + Q+G+ ++YP ++ SRFEHS+GTF+LAS+L K L+ QL + DKL I+T ++KC+E+AALCHDLGHG +SHFWE AFD S I TR HE++SVEIF+ L++ K +IK I L E+ ID I R+I G+Y + DG+K++LF+IVANK+SGLDVDK DYLCRD Y GWSN NKIHD KR+++FFRVV DE +W LAMRDRE+F ++++F R++LHRYG +H+ VKS+EC+F+ +K ++EN RDEF+ V+ ++ Y+SDIWFS+ FI++ D+HLW + + ++ I+ER L KL ++++ +GN + L DI L + L S SLS ++LQ+ENKG+PL+ +KFY+KENP FN++++SLP+ + L DE ILM+F E+ I + + + EV L K D + NL KY F+EI Y
Sbjct: 19 IIDTEEFQRLRYISQIGLTRHIYPSATCSRFEHSLGTFYLASKLIKQLKDQL--ESEDKL---IITSEEVKCVELAALCHDLGHGPHSHFWEHAFDPSLKIKTRKHEDVSVEIFRELVDQKKSTSTETIKTIIGLTEEMIDQICRMITGEYEREKDGEKKFLFQIVANKDSGLDVDKLDYLCRDSFYLGWSN-NKIHDFKRLIYFFRVVKDESTKDWHLAMRDRELFKVNEVFSFRHILHRYGCQHRVVKSIECMFRNGIKQVIENTVARDEFLETVLEQKVPYNSDIWFSKQFISKVNDYHLWHVLKKYAKEMFKNIQERNLYKLLH----QSQIQITSGNNF-DSLDNDISDLQTFLQRTSGHSNIYLSLSIYSLQTENKGDPLMLMKFYSKENPNKSFNYDKDSLPNSLSLKEDEIILMVFVERRIFDELEGVL--EVFRSLESKSYNSQEDFIMRNLQTKYLFKEIKY 477
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Match: SMESG000079627.1 (SMESG000079627.1) HSP 1 Score: 426.017 bits (1094), Expect = 1.365e-145 Identity = 227/473 (47.99%), Postives = 320/473 (67.65%), Query Frame = 3
Query: 18 QIIDTKEFQRLRQVKQLGMCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTENDMKCIEIAALCHDLGHGCYSHFWEKAFDDS--IPTRPHEELSVEIFKSLLNSSKLCYNRSIKFEIELDEKSIDLIGRIIIGKYNEKIDGKKRYLFEIVANKESGLDVDKFDYLCRDQIYFGWSNKNKIHDIKRILHFFRVVNDELNGNWRLAMRDREIFHIHDIFKTRNLLHRYGYEHKTVKSVECLFKRALKTIVENPEYRDEFITNVMGNRLDYSSDIWFSRGFINRAVDHHLWDTMSRRTPDIVARIEERCLLKLFSRFRVENKLNDVTGNEWRKELRKDIXXXXXXXXXXXXD----FSLSTFTLQSENKGNPLLSVKFYTKENPRNCFNFNENSLPDLVKLISDETILMIFAEKSIISDPDRICLNEVKDKLCGKLQPDGNDGEISNLLGKYNFREINY 1418
+IIDT+EFQRLR + Q G+ YV P ++ SRFEHS+GTF+LAS+L K L+ QL + DKL I+T ++KC+E+AALCHDLGHG +SHFWE AFD S I TR HE++SVEIF+ L++ K +IK I L E+ ID I R+I G+Y + DG+K++LF+IVANK+SGLDVDK DYLCRD Y GWSN NKIHD KR+++FFRVV DE +W LAMRDRE+F ++++F R++LHRYG +H+ VKS+EC+F+ +K ++EN RDEF+ V+ ++ Y+SDIWFS+ FI++ D+HLW + + ++ I+ER L KL ++++ +GN + L DI L + L S SLS ++LQ+ENKG+PL+ +KFY+KENP F+++++SLP+ + L DE ILM+F E+ I + + + EV L K D + NL KY F+EI Y
Sbjct: 25 EIIDTQEFQRLRYISQTGLTWYVNPSATCSRFEHSLGTFYLASKLIKQLKDQL--EGEDKL---IITSEEVKCVELAALCHDLGHGPHSHFWEHAFDPSLKIKTRKHEDVSVEIFRELVDQKKSTSTETIKTIIGLTEEMIDQICRMITGEYEREKDGEKKFLFQIVANKDSGLDVDKLDYLCRDSFYLGWSN-NKIHDFKRLIYFFRVVKDESTKDWHLAMRDRELFKVNEVFSFRHILHRYGCKHRVVKSIECMFRNGIKQVIENTVARDEFLETVLEQKVPYNSDIWFSKQFISKVNDYHLWHVLKKYAKEMFKNIQERNLYKLLH----QSQIQITSGNNF-DSLDNDISDLQTFLQRTSGHSNIYLSLSIYSLQTENKGDPLMLMKFYSKENPNKSFDYDKDSLPNSLSLKEDEIILMVFVERRIFDELEGVL--EVFRSLESKSYNSQEDFIMRNLQTKYLFKEIKY 484 The following BLAST results are available for this feature:
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of deoxynucleoside triphosphate triphosphohydrolase SAMHD1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001300 ID=SMED30001300|Name=deoxynucleoside triphosphate triphosphohydrolase SAMHD1|organism=Schmidtea mediterranea sexual|type=transcript|length=1447bpback to top protein sequence of SMED30001300-orf-1 >SMED30001300-orf-1 ID=SMED30001300-orf-1|Name=SMED30001300-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=450bp MCIYVYPCSSYSRFEHSIGTFHLASELTKLLRVQLLMDYGDKLCEEILTEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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