Ubiquitin-fold modifier 1

Overview
NameUbiquitin-fold modifier 1
Smed IDSMED30001280
Length (bp)551
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ubiquitin-fold modifier 1 (SMED30001280) t-SNE clustered cells

Violin plots show distribution of expression levels for Ubiquitin-fold modifier 1 (SMED30001280) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ubiquitin-fold modifier 1 (SMED30001280) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ubiquitin-fold modifier 1 (SMED30001280) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001280

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30001280 dd_Smed_v4_3114_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Human
Match: UFM1 (ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597])

HSP 1 Score: 145.976 bits (367), Expect = 2.066e-45
Identity = 70/84 (83.33%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELR+IPRDRVGS 
Sbjct:    2 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Human
Match: UFM1 (ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597])

HSP 1 Score: 113.62 bits (283), Expect = 2.121e-32
Identity = 53/65 (81.54%), Postives = 57/65 (87.69%), Query Frame = 1 
Query:  139 LKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            L VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELR+IPRDRVGS 
Sbjct:   39 LSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC 103
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Human
Match: UFM1 (ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597])

HSP 1 Score: 111.694 bits (278), Expect = 4.668e-32
Identity = 56/68 (82.35%), Postives = 60/68 (88.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLK 285
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAGE +LK
Sbjct:    3 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGE-YLK 69
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Celegans
Match: ufm-1 (Ubiquitin-fold modifier 1 [Source:UniProtKB/Swiss-Prot;Acc:P34661])

HSP 1 Score: 141.354 bits (355), Expect = 7.874e-44
Identity = 67/82 (81.71%), Postives = 73/82 (89.02%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVG 327
            SKV+FKITLTSDP LPFKVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDG+G+NP Q AG +FLK+GSELRLIPRDRVG
Sbjct:   12 SKVTFKITLTSDPKLPFKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGVGVNPAQPAGNIFLKHGSELRLIPRDRVG 93
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Fly
Match: Ufm1 (gene:FBgn0085220 transcript:FBtr0340071)

HSP 1 Score: 140.969 bits (354), Expect = 8.470e-44
Identity = 68/85 (80.00%), Postives = 75/85 (88.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSLL 336
            SKV+FKITLTSDP LPFKVL VPE  PFTAVLK+ +EEFKVP  TSAIIT+DGIG++PQQTAG VFLK+GSELRLIPRDRVG  L
Sbjct:    2 SKVTFKITLTSDPKLPFKVLSVPEGTPFTAVLKFASEEFKVPAETSAIITDDGIGISPQQTAGNVFLKHGSELRLIPRDRVGHQL 86
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Fly
Match: Ufm1 (gene:FBgn0085220 transcript:FBtr0112384)

HSP 1 Score: 140.969 bits (354), Expect = 8.470e-44
Identity = 68/85 (80.00%), Postives = 75/85 (88.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSLL 336
            SKV+FKITLTSDP LPFKVL VPE  PFTAVLK+ +EEFKVP  TSAIIT+DGIG++PQQTAG VFLK+GSELRLIPRDRVG  L
Sbjct:    2 SKVTFKITLTSDPKLPFKVLSVPEGTPFTAVLKFASEEFKVPAETSAIITDDGIGISPQQTAGNVFLKHGSELRLIPRDRVGHQL 86
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Zebrafish
Match: ufm1 (ubiquitin-fold modifier 1 [Source:NCBI gene;Acc:322756])

HSP 1 Score: 142.51 bits (358), Expect = 3.660e-44
Identity = 68/82 (82.93%), Postives = 74/82 (90.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVG 327
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELR+IPRDRVG
Sbjct:    2 SKVTFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVG 83
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Xenopus
Match: ufm1 (ubiquitin-fold modifier 1 [Source:NCBI gene;Acc:549742])

HSP 1 Score: 146.362 bits (368), Expect = 1.364e-45
Identity = 71/84 (84.52%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIGLNP QTAG VFLK+GSELRLIPRDRVGS 
Sbjct:    2 SKVTFKITLTSDPRLPYKVLCVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGLNPAQTAGNVFLKHGSELRLIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Mouse
Match: Ufm1 (ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:MGI:1915140])

HSP 1 Score: 145.976 bits (367), Expect = 1.418e-45
Identity = 70/84 (83.33%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELR+IPRDRVGS 
Sbjct:    2 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Mouse
Match: Ufm1 (ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:MGI:1915140])

HSP 1 Score: 115.931 bits (289), Expect = 7.320e-34
Identity = 57/76 (75.00%), Postives = 63/76 (82.89%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLI 309
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAGE  L   S+L ++
Sbjct:    2 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGECLLVCPSKLNIL 77
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Mouse
Match: Ufm1 (ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:MGI:1915140])

HSP 1 Score: 85.5001 bits (210), Expect = 3.142e-22
Identity = 43/51 (84.31%), Postives = 45/51 (88.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITN 234
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITN
Sbjct:    2 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITN 52
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Match: sp|Q176V0|UFM1_AEDAE (Ubiquitin-fold modifier 1 OS=Aedes aegypti OX=7159 GN=AAEL006251 PE=3 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 2.630e-46
Identity = 72/83 (86.75%), Postives = 77/83 (92.77%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGS 330
            SKV+FKITLTSDP LPFKVL VPE  PFTAVLK+ AEEFKVPPATSAIIT+DGIG+NPQQTAG VFLK+GSELRLIPRDRVGS
Sbjct:    3 SKVTFKITLTSDPKLPFKVLSVPEATPFTAVLKFAAEEFKVPPATSAIITDDGIGINPQQTAGNVFLKHGSELRLIPRDRVGS 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Match: sp|Q7PXE2|UFM1_ANOGA (Ubiquitin-fold modifier 1 OS=Anopheles gambiae OX=7165 GN=AGAP001364 PE=3 SV=3)

HSP 1 Score: 148.673 bits (374), Expect = 1.013e-45
Identity = 71/83 (85.54%), Postives = 76/83 (91.57%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGS 330
            SKV+FKITLTSDP LPFKVL VPE  PFTAVLK+ AEEFKVPPATSAIIT+DGIG+NPQQTAG VFLK+GSELRLIPRDRVG 
Sbjct:    4 SKVTFKITLTSDPKLPFKVLSVPEATPFTAVLKFAAEEFKVPPATSAIITDDGIGINPQQTAGTVFLKHGSELRLIPRDRVGC 86
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Match: sp|Q5BJP3|UFM1_RAT (Ubiquitin-fold modifier 1 OS=Rattus norvegicus OX=10116 GN=Ufm1 PE=3 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 4.095e-45
Identity = 71/84 (84.52%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKVSFKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELRLIPRDRVGS 
Sbjct:    2 SKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRLIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Match: sp|B3DL37|UFM1_XENTR (Ubiquitin-fold modifier 1 OS=Xenopus tropicalis OX=8364 GN=ufm1 PE=3 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 7.226e-45
Identity = 71/84 (84.52%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIGLNP QTAG VFLK+GSELRLIPRDRVGS 
Sbjct:    2 SKVTFKITLTSDPRLPYKVLCVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGLNPAQTAGNVFLKHGSELRLIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Match: sp|Q5RJW4|UFM1_XENLA (Ubiquitin-fold modifier 1 OS=Xenopus laevis OX=8355 GN=ufm1 PE=3 SV=1)

HSP 1 Score: 146.362 bits (368), Expect = 7.226e-45
Identity = 71/84 (84.52%), Postives = 75/84 (89.29%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIGLNP QTAG VFLK+GSELRLIPRDRVGS 
Sbjct:    2 SKVTFKITLTSDPRLPYKVLCVPENTPFTAVLKFAAEEFKVPAATSAIITNDGIGLNPAQTAGNVFLKHGSELRLIPRDRVGSC 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Match: A0A183JCB2 (Ubiquitin-fold modifier 1 OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS319 PE=3 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 5.099e-45
Identity = 73/84 (86.90%), Postives = 79/84 (94.05%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SK+SFKITLTSDPNLPFKVLKVPE APFTAVLK+ AEEF VP ATSAIIT+DGIG+NPQQTAGEVFLK+GS+LRLIPRDRVG L
Sbjct:    5 SKISFKITLTSDPNLPFKVLKVPENAPFTAVLKFAAEEFSVPAATSAIITDDGIGINPQQTAGEVFLKHGSDLRLIPRDRVGGL 88
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Match: A0A183RA27 (Uncharacterized protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 5.100e-45
Identity = 74/88 (84.09%), Postives = 81/88 (92.05%), Query Frame = 1 
Query:   70 SPPPSKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            +P  SK+SFKITLTSDPNLPFKVLKVPE APFTAVLK+ AEEF VP ATSAIIT+DGIG+NPQQTAGEVFLK+GS+LRLIPRDRVG L
Sbjct:   26 NPDWSKISFKITLTSDPNLPFKVLKVPENAPFTAVLKFAAEEFSVPAATSAIITDDGIGINPQQTAGEVFLKHGSDLRLIPRDRVGGL 113
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Match: A0A183LNY9 (Ubiquitin-fold modifier 1 OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS5514 PE=3 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 5.299e-45
Identity = 73/84 (86.90%), Postives = 79/84 (94.05%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SK+SFKITLTSDPNLPFKVLKVPE APFTAVLK+ AEEF VP ATSAIIT+DGIG+NPQQTAGEVFLK+GS+LRLIPRDRVG L
Sbjct:   16 SKISFKITLTSDPNLPFKVLKVPENAPFTAVLKFAAEEFSVPAATSAIITDDGIGINPQQTAGEVFLKHGSDLRLIPRDRVGGL 99
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Match: C4QLP6 (Ubiquitin-fold modifier 1 OS=Schistosoma mansoni OX=6183 GN=Smp_091230 PE=3 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 5.737e-45
Identity = 73/84 (86.90%), Postives = 79/84 (94.05%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SK+SFKITLTSDPNLPFKVLKVPE APFTAVLK+ AEEF VP ATSAIIT+DGIG+NPQQTAGEVFLK+GS+LRLIPRDRVG L
Sbjct:    2 SKISFKITLTSDPNLPFKVLKVPENAPFTAVLKFAAEEFSVPAATSAIITDDGIGINPQQTAGEVFLKHGSDLRLIPRDRVGGL 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Match: C1LEE9 (Ubiquitin-fold modifier 1 OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 1.002e-44
Identity = 72/84 (85.71%), Postives = 80/84 (95.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGSL 333
            SK+SFKITLTS+PNLPFKVLKVPE APFTAVLK+ AEEF VP ATSAIIT+DGIG+NPQQTAGE+FLK+GS+LRLIPRDRVGSL
Sbjct:    2 SKISFKITLTSNPNLPFKVLKVPENAPFTAVLKFAAEEFDVPAATSAIITDDGIGINPQQTAGEIFLKHGSDLRLIPRDRVGSL 85
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Cavefish
Match: ufm1 (ubiquitin fold modifier 1 [Source:NCBI gene;Acc:103028639])

HSP 1 Score: 144.05 bits (362), Expect = 7.562e-45
Identity = 68/83 (81.93%), Postives = 75/83 (90.36%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGS 330
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSAIITNDGIG+NP QTAG VFLK+GSELR+IPRDRVG+
Sbjct:    2 SKVTFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGA 84
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Nematostella
Match: EDO47078 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN57])

HSP 1 Score: 144.436 bits (363), Expect = 1.954e-45
Identity = 68/82 (82.93%), Postives = 75/82 (91.46%), Query Frame = 1 
Query:   85 KVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVGS 330
            KV+FKITLTSDP LP+KVL VPE  PFTAVL++ AEEFKVPPATSAIITNDGIG+NP Q+AG VFLK+GSELRLIPRDRVGS
Sbjct:    2 KVTFKITLTSDPKLPYKVLSVPENTPFTAVLRFAAEEFKVPPATSAIITNDGIGINPTQSAGNVFLKHGSELRLIPRDRVGS 83
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Medaka
Match: ufm1 (ubiquitin fold modifier 1 [Source:NCBI gene;Acc:101168639])

HSP 1 Score: 142.895 bits (359), Expect = 2.009e-44
Identity = 68/82 (82.93%), Postives = 74/82 (90.24%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSELRLIPRDRVG 327
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSA+ITNDGIG+NP QTAG VFLK+GSELRLIPRDRVG
Sbjct:    2 SKVTFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAVITNDGIGINPAQTAGNVFLKHGSELRLIPRDRVG 83
[Close]
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Medaka
Match: ufm1 (ubiquitin fold modifier 1 [Source:NCBI gene;Acc:101168639])

HSP 1 Score: 107.842 bits (268), Expect = 1.121e-30
Identity = 51/65 (78.46%), Postives = 58/65 (89.23%), Query Frame = 1 
Query:   82 SKVSFKITLTSDPNLPFKVLKVPEQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEV 276
            SKV+FKITLTSDP LP+KVL VPE  PFTAVLK+ AEEFKVP ATSA+ITNDGIG+NP QTAG++
Sbjct:    2 SKVTFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAVITNDGIGINPAQTAGKL 66
The following BLAST results are available for this feature:
BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
UFM12.066e-4583.33ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:... [more]
UFM12.121e-3281.54ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:... [more]
UFM14.668e-3282.35ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ufm-17.874e-4481.71Ubiquitin-fold modifier 1 [Source:UniProtKB/Swiss... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Ufm18.470e-4480.00gene:FBgn0085220 transcript:FBtr0340071[more]
Ufm18.470e-4480.00gene:FBgn0085220 transcript:FBtr0112384[more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ufm13.660e-4482.93ubiquitin-fold modifier 1 [Source:NCBI gene;Acc:32... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ufm11.364e-4584.52ubiquitin-fold modifier 1 [Source:NCBI gene;Acc:54... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Ufm11.418e-4583.33ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:M... [more]
Ufm17.320e-3475.00ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:M... [more]
Ufm13.142e-2284.31ubiquitin-fold modifier 1 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q176V0|UFM1_AEDAE2.630e-4686.75Ubiquitin-fold modifier 1 OS=Aedes aegypti OX=7159... [more]
sp|Q7PXE2|UFM1_ANOGA1.013e-4585.54Ubiquitin-fold modifier 1 OS=Anopheles gambiae OX=... [more]
sp|Q5BJP3|UFM1_RAT4.095e-4584.52Ubiquitin-fold modifier 1 OS=Rattus norvegicus OX=... [more]
sp|B3DL37|UFM1_XENTR7.226e-4584.52Ubiquitin-fold modifier 1 OS=Xenopus tropicalis OX... [more]
sp|Q5RJW4|UFM1_XENLA7.226e-4584.52Ubiquitin-fold modifier 1 OS=Xenopus laevis OX=835... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183JCB25.099e-4586.90Ubiquitin-fold modifier 1 OS=Schistosoma curassoni... [more]
A0A183RA275.100e-4584.09Uncharacterized protein OS=Schistosoma rodhaini OX... [more]
A0A183LNY95.299e-4586.90Ubiquitin-fold modifier 1 OS=Schistosoma margrebow... [more]
C4QLP65.737e-4586.90Ubiquitin-fold modifier 1 OS=Schistosoma mansoni O... [more]
C1LEE91.002e-4485.71Ubiquitin-fold modifier 1 OS=Schistosoma japonicum... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ufm17.562e-4581.93ubiquitin fold modifier 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO470781.954e-4582.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ufm12.009e-4482.93ubiquitin fold modifier 1 [Source:NCBI gene;Acc:10... [more]
ufm11.121e-3078.46ubiquitin fold modifier 1 [Source:NCBI gene;Acc:10... [more]
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BLAST of Ubiquitin-fold modifier 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 0
Match NameE-valueIdentityDescription
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001280 ID=SMED30001280|Name=Ubiquitin-fold modifier 1|organism=Schmidtea mediterranea sexual|type=transcript|length=551bp
ATGTTGAGAATTGGAATCAATGTGGGAGCACTCGCCGTGAAATTGAAAAA
ATTAGCAATGTCACGTGTGAGCCCTCCGCCGTCTAAAGTATCTTTTAAAA
TAACTTTAACATCTGATCCAAATTTGCCATTTAAAGTGCTCAAAGTTCCA
GAACAAGCACCGTTTACGGCAGTATTAAAATATGTTGCTGAAGAATTCAA
AGTCCCACCTGCTACAAGCGCTATTATTACCAATGATGGAATAGGCCTAA
ATCCTCAACAAACGGCTGGTGAGGTTTTTCTGAAATATGGAAGTGAATTA
AGGTTGATTCCAAGAGACAGAGTTGGATCTTTATTATTTTAAATGTGACA
TTTTGAGTTAATTGCAACGTTTATTTTACATGAATTCAATATTATGTGTT
CTTGTTTTTGAAATCAGATTAACTTATTACGTTAAAAAATTGTACAAGTA
TTTTAAATTTTACGAATCTGATTGGAAATCATTTTGACTTATTTGATAAC
ATTAAATTTATATCAATTATTAATTTTGATGAAATATAATTTTTTGAAAC
C
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protein sequence of SMED30001280-orf-1

>SMED30001280-orf-1 ID=SMED30001280-orf-1|Name=SMED30001280-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=114bp
MLRIGINVGALAVKLKKLAMSRVSPPPSKVSFKITLTSDPNLPFKVLKVP
EQAPFTAVLKYVAEEFKVPPATSAIITNDGIGLNPQQTAGEVFLKYGSEL
RLIPRDRVGSLLF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0071569protein ufmylation
GO:1990592protein K69-linked ufmylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR005375UFM1
IPR029071Ubiquitin-like_domsf
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm