Meiotic recombination protein rec8

Overview
NameMeiotic recombination protein rec8
Smed IDSMED30001230
Length (bp)1980
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Meiotic recombination protein rec8 (SMED30001230) t-SNE clustered cells

Violin plots show distribution of expression levels for Meiotic recombination protein rec8 (SMED30001230) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Meiotic recombination protein rec8 (SMED30001230) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Meiotic recombination protein rec8 (SMED30001230) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001230

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30001230SMESG000041612.1 SmedASXL_017465SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X1 cellSMED30001230SMESG000041612.1 SmedASXL_017464SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30001230SMESG000041612.1 dd_Smed_v4_15392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001230SMESG000041612.1 dd_Smed_v4_15392_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Match: REC8 (REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879])

HSP 1 Score: 65.855 bits (159), Expect = 1.400e-10
Identity = 36/99 (36.36%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKK 286
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q + ++
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILER 98
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Match: REC8 (REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879])

HSP 1 Score: 65.855 bits (159), Expect = 1.400e-10
Identity = 36/99 (36.36%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKK 286
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q + ++
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILER 98
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Match: REC8 (REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879])

HSP 1 Score: 65.855 bits (159), Expect = 1.400e-10
Identity = 36/99 (36.36%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKK 286
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q + ++
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILER 98
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Match: REC8 (REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879])

HSP 1 Score: 65.855 bits (159), Expect = 1.400e-10
Identity = 36/99 (36.36%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKK 286
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q + ++
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILER 98
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Match: RAD21 (RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811])

HSP 1 Score: 62.003 bits (149), Expect = 2.263e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Celegans
Match: coh-1 (COHesin family [Source:UniProtKB/TrEMBL;Acc:A0A131MBD0])

HSP 1 Score: 59.3066 bits (142), Expect = 6.898e-9
Identity = 52/185 (28.11%), Postives = 82/185 (44.32%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNL---ENNHEGTDMDLTNQIAYLNQARFEDITMME-------YDYGQ 541
             F +D ++ K+G  + +WLAA   EK L+K  +   D+  A +EIM         KL+L  +  L  G+C +Y +K   LL D  + + K  + F    ++Q +             L   SI D +G+  D+  VL      E NH           A + Q+R +DIT+ E       Y+YG+
Sbjct:    1 MFYADFVLSKKGPLSKVWLAA-HWEKKLSKAQIFETDVDEAVNEIM-----QPSQKLALRTTGHLLLGICRVYSRKTKYLLADCNEAFLKIKLVFRSGALDQPN-----------PVLPTFSIQDIYGDFGDN--VLPEFDEEELNH-----------APICQSRLDDITLKEDIPQKFTYNYGE 155
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Celegans
Match: scc-1 (Sister chromatid cohesion protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q19325])

HSP 1 Score: 56.225 bits (134), Expect = 5.280e-8
Identity = 48/169 (28.40%), Postives = 71/169 (42.01%), Query Frame = 2 
Query:   20 FSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            F +  ++ K+G    +WLAA   EK LTK  +   D+  A  E++       K+K++L     L  G+  IY KK   LL D  + Y+K  + F      + D    A+            I +DF    D + +        E  D D   Q+   N +R EDITM E
Sbjct:    2 FYAQFVLAKKGPLAKVWLAA-HWEKKLTKAQIFETDVPQAIEEVI-----RPKVKMALRTVGHLLLGIVRIYSKKTRYLLADTNEAYQKMKINFRNGFSFEVDIPENAE------------IEEDFSNFIDKYNITV-----PEFHDADYNEQLIMANVSRREDITMKE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Fly
Match: vtd (gene:FBgn0260987 transcript:FBtr0113746)

HSP 1 Score: 54.299 bits (129), Expect = 3.387e-7
Identity = 48/184 (26.09%), Postives = 86/184 (46.74%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDN 568
             F   +++ K+G    IWLAA   +K +TK  +   ++  +   I+       K+KL+L  S  L  G+  IY +K   LL D  + + K  + F    V+  + +R A       N+  +++ + F + + +   L          D+D+  Q + +NQ+R ++ITM E DYG  ++  Q D 
Sbjct:    1 MFYEHIILAKKGPLARIWLAA-HWDKKITKAHVFETNIEKSVEGIL-----QPKVKLALRTSGHLLLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREA-------NVNAITLPEVFHDFDTALPEL---------NDIDIEAQFS-INQSRADEITMRE-DYGSLSLSLQDDG 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Fly
Match: vtd (gene:FBgn0260987 transcript:FBtr0344093)

HSP 1 Score: 53.9138 bits (128), Expect = 4.082e-7
Identity = 48/184 (26.09%), Postives = 86/184 (46.74%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDN 568
             F   +++ K+G    IWLAA   +K +TK  +   ++  +   I+       K+KL+L  S  L  G+  IY +K   LL D  + + K  + F    V+  + +R A       N+  +++ + F + + +   L          D+D+  Q + +NQ+R ++ITM E DYG  ++  Q D 
Sbjct:    1 MFYEHIILAKKGPLARIWLAA-HWDKKITKAHVFETNIEKSVEGIL-----QPKVKLALRTSGHLLLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREA-------NVNAITLPEVFHDFDTALPEL---------NDIDIEAQFS-INQSRADEITMRE-DYGSLSLSLQDDG 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Match: rec8a (REC8 meiotic recombination protein a [Source:ZFIN;Acc:ZDB-GENE-081104-283])

HSP 1 Score: 83.1889 bits (204), Expect = 2.406e-16
Identity = 40/101 (39.60%), Postives = 64/101 (63.37%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRH--------QKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSL 292
            MFF   +L  + G+F  IWLAAT+G K ++++DL  V++H+ C++IMD+VL           + + SLYLSSQL +G+ +++H++ + LL D Q    K L
Sbjct:    1 MFFYPTVLNHRTGRFATIWLAATKGRK-ISRRDLLKVNVHNTCNDIMDFVLVRVPPPMAGLPRPRFSLYLSSQLQYGVVLVFHRQCEFLLEDTQGAIDKLL 100
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Match: rec8b (REC8 meiotic recombination protein b [Source:ZFIN;Acc:ZDB-GENE-060421-4898])

HSP 1 Score: 71.633 bits (174), Expect = 1.275e-12
Identity = 37/116 (31.90%), Postives = 68/116 (58.62%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRH--------QKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNR 337
            MF+  ++L    G F+ IWLAAT+G + ++++D   V++   C +I+DYV+           + + SLYLSSQL +G+ ++YH++   LL ++Q   ++ L +    N++  D +R
Sbjct:    1 MFYYPNVLQRHTGCFSTIWLAATKGIR-ISRRDYLKVNVRRTCEDIVDYVMVQVPPVHPSLPRPRFSLYLSSQLQYGVIIVYHRQCAFLLEEVQQTIERLLRSKRHLNIDMPDNDR 115
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Match: rad21a (RAD21 cohesin complex component a [Source:NCBI gene;Acc:322275])

HSP 1 Score: 61.6178 bits (148), Expect = 2.166e-9
Identity = 57/186 (30.65%), Postives = 86/186 (46.24%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDL 574
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E + G  NI    DND 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-EVG--NISLMTDNDF 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Match: rad21a (RAD21 cohesin complex component a [Source:NCBI gene;Acc:322275])

HSP 1 Score: 61.6178 bits (148), Expect = 2.166e-9
Identity = 57/186 (30.65%), Postives = 86/186 (46.24%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDL 574
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E + G  NI    DND 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-EVG--NISLMTDNDF 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Match: rad21b (RAD21 cohesin complex component b [Source:ZFIN;Acc:ZDB-GENE-060503-223])

HSP 1 Score: 61.2326 bits (147), Expect = 2.581e-9
Identity = 51/170 (30.00%), Postives = 79/170 (46.47%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:Xenbase;Acc:XB-GENE-484872])

HSP 1 Score: 66.6254 bits (161), Expect = 7.243e-11
Identity = 37/102 (36.27%), Postives = 59/102 (57.84%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKI--------KLSLYLSSQLTFGLCVIYHKKIDKLL----NDLQDLYK 283
            MF+  ++L    G F  IWLAAT+G K L ++ L  V++ + C +IM+Y+L             + SLYLS+QL++G+  +YH++ D L+    N L  +YK
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATKGTKILKREYLK-VNVINTCQQIMEYLLLQVPPPQVGLPVPRFSLYLSAQLSYGVVRVYHRQCDLLIEEMKNTLDRIYK 101
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Match: mdh1 (malate dehydrogenase 1 [Source:Xenbase;Acc:XB-GENE-484872])

HSP 1 Score: 66.6254 bits (161), Expect = 8.334e-11
Identity = 37/102 (36.27%), Postives = 59/102 (57.84%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKI--------KLSLYLSSQLTFGLCVIYHKKIDKLL----NDLQDLYK 283
            MF+  ++L    G F  IWLAAT+G K L ++ L  V++ + C +IM+Y+L             + SLYLS+QL++G+  +YH++ D L+    N L  +YK
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATKGTKILKREYLK-VNVINTCQQIMEYLLLQVPPPQVGLPVPRFSLYLSAQLSYGVVRVYHRQCDLLIEEMKNTLDRIYK 101
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Match: RAD21 (RAD21 cohesin complex component [Source:NCBI gene;Acc:100492023])

HSP 1 Score: 62.7734 bits (151), Expect = 1.503e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Match: RAD21 (RAD21 cohesin complex component [Source:NCBI gene;Acc:100492023])

HSP 1 Score: 62.3882 bits (150), Expect = 1.654e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Match: RAD21 (RAD21 cohesin complex component [Source:NCBI gene;Acc:100492023])

HSP 1 Score: 61.6178 bits (148), Expect = 2.055e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Mouse
Match: Rec8 (REC8 meiotic recombination protein [Source:MGI Symbol;Acc:MGI:1929645])

HSP 1 Score: 65.0846 bits (157), Expect = 2.069e-10
Identity = 36/96 (37.50%), Postives = 57/96 (59.38%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDL 277
            MF+  ++L    G F  IWLAATRG + + ++ LN V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q +
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLN-VNVVKTCEEILNYVLVRVQPPVAGLPRPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHI 95
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Mouse
Match: Rad21 (RAD21 cohesin complex component [Source:MGI Symbol;Acc:MGI:108016])

HSP 1 Score: 59.6918 bits (143), Expect = 4.425e-10
Identity = 49/169 (28.99%), Postives = 81/169 (47.93%), Query Frame = 2 
Query:   20 FSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A           +++ ++F + +     L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    2 FYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA-------YNAITLPEEFHDFDQP---LPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Mouse
Match: Rad21 (RAD21 cohesin complex component [Source:MGI Symbol;Acc:MGI:108016])

HSP 1 Score: 62.3882 bits (150), Expect = 1.301e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Match: sp|O95072|REC8_HUMAN (Meiotic recombination protein REC8 homolog OS=Homo sapiens OX=9606 GN=REC8 PE=1 SV=1)

HSP 1 Score: 65.855 bits (159), Expect = 6.725e-10
Identity = 36/99 (36.36%), Postives = 58/99 (58.59%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKK 286
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q + ++
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLRVNVVKTCEEILNYVLVRVQPPQPGLPRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILER 98
[Close]
BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Match: sp|Q8C5S7|REC8_MOUSE (Meiotic recombination protein REC8 homolog OS=Mus musculus OX=10090 GN=Rec8 PE=1 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.447e-9
Identity = 36/96 (37.50%), Postives = 57/96 (59.38%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDL 277
            MF+  ++L    G F  IWLAATRG + + ++ LN V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q +
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLN-VNVVKTCEEILNYVLVRVQPPVAGLPRPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQHI 95
[Close]
BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Match: sp|Q6AYJ4|REC8_RAT (Meiotic recombination protein REC8 homolog OS=Rattus norvegicus OX=10116 GN=Rec8 PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 2.482e-9
Identity = 36/94 (38.30%), Postives = 55/94 (58.51%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVL-RHQ-------KIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQ 271
            MF+  ++L    G F  IWLAATRG + L K++   V++   C EI++YVL R Q       + + SLYLS+QL  G+  +Y ++   L+ D+Q
Sbjct:    1 MFYYPNVLQRHTGCFATIWLAATRGSR-LVKREYLKVNVVKTCEEILNYVLVRVQPPMPGLPRPRFSLYLSAQLQIGVIRVYFQQCQYLVEDIQ 93
[Close]
BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Match: sp|Q61550|RAD21_MOUSE (Double-strand-break repair protein rad21 homolog OS=Mus musculus OX=10090 GN=Rad21 PE=1 SV=3)

HSP 1 Score: 62.3882 bits (150), Expect = 9.101e-9
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Match: sp|Q3SWX9|RAD21_BOVIN (Double-strand-break repair protein rad21 homolog OS=Bos taurus OX=9913 GN=RAD21 PE=2 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 1.004e-8
Identity = 51/170 (30.00%), Postives = 80/170 (47.06%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q + LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFS-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Match: A0A0X3PXB2 (Meiotic recombination protein REC8 homolog (Fragment) OS=Schistocephalus solidus OX=70667 GN=REC8 PE=4 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 5.286e-27
Identity = 72/175 (41.14%), Postives = 107/175 (61.14%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSIL----DDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            MF+S +LL  +RGKF ++WLAATRG K++TK+D+   D+  +C E+M Y+   +K KLSLYLS+QL FG+C ++ +KI  +L D QDLY +SLV F    V Q D +R  ++   K ++  + I     DDFG + +  G L   + + E T  +  +  +   QAR EDIT+ E
Sbjct:   17 MFYSRELLSLRRGKFGILWLAATRGTKFITKRDIISFDIESSCVELMAYIAGAKKTKLSLYLSAQLAFGMCRVFCEKIRLILRDAQDLYSRSLVVFR-PQVTQIDDSRLLQQ--KKPDMMDIEIPLQSHDDFGSL-EYPGALCQSQLDWEITRKNFEDSFSL--QARVEDITLNE 185
[Close]
BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Match: A0A068Y568 (Meiotic recombination protein rec8 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000722900 PE=4 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 5.877e-27
Identity = 67/172 (38.95%), Postives = 110/172 (63.95%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTM-VSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            MF+S+DLL  K+G+F ++WLAATRG   ++K+D+  VD+  +CSE+++YV   ++ +LSLYLS+QL +GLC +Y +K+  +L D  DLY ++LV+F  ++V  +D  +   K R   ++ + ++  DDFG  N   G L   + + E +   L N  +   QAR EDIT+++
Sbjct:    1 MFYSNDLLSLKKGRFGVLWLAATRGVTRVSKRDILAVDIVSSCSELLEYVNGSKRSRLSLYLSAQLMYGLCRVYVEKVCIVLRDANDLYSRALVSFRPHSVQIADVRKSRGKSRCDVDIELPLTSNDDFGSFN-LLGQLVASQPDFEISMPSLDNSFSL--QARLEDITLID 169
[Close]
BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Match: A0A068X0T7 (Meiotic recombination protein rec8 OS=Echinococcus granulosus OX=6210 GN=EgrG_000722900 PE=4 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 3.478e-26
Identity = 68/173 (39.31%), Postives = 110/173 (63.58%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNV--NQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            MF+S+DLL  K+G+F ++WLAATRG   ++K+D+  VD+  +CSE+++YV   ++ +LSLYLS+QL +GLC +Y +K+  +L D  DLY ++LV+F  ++V  ++  ++RG  +      L + S  DDFG  N   G L   + + E +   L N  +   QAR EDIT+++
Sbjct:    1 MFYSNDLLSLKKGRFGVLWLAATRGVTRVSKRDILAVDIVSSCSELLEYVNGSKRSRLSLYLSAQLMYGLCRVYVEKVCIVLRDANDLYSRALVSFRPHSVQIDEVRKSRGKSRCDVDIELPLTSN-DDFGSFN-LLGQLVASQPDFEISMPSLDNSFSL--QARLEDITLID 169
[Close]
BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Match: A0A4S2M2B9 (Rad21_Rec8_N domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004483 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.130e-25
Identity = 73/190 (38.42%), Postives = 113/190 (59.47%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVN-----QSDRNRGAKKGR--DKHNLTMVSILDDFGEINDSFGV-LKNLENNHEGTDMDLTNQI-AYLNQARFEDITMMEYDYGQNNIRN 556
            MF+S +LL   RGKF+LIWLAATR  K L++++LN VD+  AC+EI   +    +++ SLYL+SQLTFGLC+IY +K + +L DLQ+L+ +    F   +V+      S +    KK R  ++ ++  + + D    + DS  + L +L  +  G D+DL +     L QAR EDIT+ME +    ++ N
Sbjct:    1 MFYSVELLSIHRGKFSLIWLAATRMRKKLSRRELNSVDIVDACNEIASCISGRTRVRFSLYLASQLTFGLCIIYREKTEYVLRDLQELFCRGRFIFQPTSVDLPISAPSTKESHTKKRRRDEQPDMPELPLAD---PLRDSVTLELPDL-VHIAGVDLDLFDMTQTSLYQARVEDITLMEENISLISVSN 186
[Close]
BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Match: A0A4S2M2K6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_004483 PE=4 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 2.440e-25
Identity = 73/190 (38.42%), Postives = 113/190 (59.47%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVN-----QSDRNRGAKKGR--DKHNLTMVSILDDFGEINDSFGV-LKNLENNHEGTDMDLTNQI-AYLNQARFEDITMMEYDYGQNNIRN 556
            MF+S +LL   RGKF+LIWLAATR  K L++++LN VD+  AC+EI   +    +++ SLYL+SQLTFGLC+IY +K + +L DLQ+L+ +    F   +V+      S +    KK R  ++ ++  + + D    + DS  + L +L  +  G D+DL +     L QAR EDIT+ME +    ++ N
Sbjct:    1 MFYSVELLSIHRGKFSLIWLAATRMRKKLSRRELNSVDIVDACNEIASCISGRTRVRFSLYLASQLTFGLCIIYREKTEYVLRDLQELFCRGRFIFQPTSVDLPISAPSTKESHTKKRRRDEQPDMPELPLADP---LRDSVTLELPDL-VHIAGVDLDLFDMTQTSLYQARVEDITLMEENISLISVSN 186
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Cavefish
Match: rad21b (RAD21 cohesin complex component [Source:NCBI gene;Acc:103023059])

HSP 1 Score: 61.6178 bits (148), Expect = 1.970e-9
Identity = 51/170 (30.00%), Postives = 79/170 (46.47%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFC-LNQSRVEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Cavefish
Match: rad21a (double-strand-break repair protein rad21 homolog [Source:NCBI gene;Acc:103039334])

HSP 1 Score: 61.2326 bits (147), Expect = 2.225e-9
Identity = 56/186 (30.11%), Postives = 86/186 (46.24%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDL 574
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E + G  N+    DND 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-EVG--NLSIMADNDF 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Cavefish
Match: rad21a (double-strand-break repair protein rad21 homolog [Source:NCBI gene;Acc:103039334])

HSP 1 Score: 61.2326 bits (147), Expect = 2.225e-9
Identity = 56/186 (30.11%), Postives = 86/186 (46.24%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDL 574
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E + G  N+    DND 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESII-----SPKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-EVG--NLSIMADNDF 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Cavefish
Match: rad21a (double-strand-break repair protein rad21 homolog [Source:NCBI gene;Acc:103039334])

HSP 1 Score: 60.8474 bits (146), Expect = 2.706e-9
Identity = 56/186 (30.11%), Postives = 86/186 (46.24%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDL 574
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E + G  N+    DND 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-EVG--NLSIMADNDF 160
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Sea Lamprey
Match: RAD21 (RAD21 cohesin complex component [Source:HGNC Symbol;Acc:HGNC:9811])

HSP 1 Score: 60.077 bits (144), Expect = 1.029e-9
Identity = 50/171 (29.24%), Postives = 77/171 (45.03%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            MF++   ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IY +K   LL D  + + K  + F    V+  + NR A      + +T+     DF +     G            D+D+  Q   LNQ+R E+ITM E
Sbjct:    1 MFYAH-FVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGVVDLPEENREAAY----NAITLPEEFHDFDQPLPDLG------------DIDVAQQFT-LNQSRLEEITMRE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Nematostella
Match: EDO38394 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY1])

HSP 1 Score: 51.6026 bits (122), Expect = 8.384e-7
Identity = 43/171 (25.15%), Postives = 78/171 (45.61%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMME 526
            MF+ +  ++ K+G    +WLAA   EK L+K  +   D+  +   I+       K+K++L  S  L  G+  IY +K   LL D  + + K  + F    V+  +  R       +     +++ + F +++ +   L ++E   + T          LNQ+R E+ITM E
Sbjct:    1 MFYHT-FILAKKGPMARVWLAA-HWEKKLSKSVVFETDIKSSVESIVS-----PKMKMALRTSGHLLLGVVRIYSRKAKYLLADCSEAFVKIKMAFRPGVVDLPEDGR-------ELAFAAITLPEAFTDLDMTLPELNDVEIQAQFT----------LNQSRIEEITMKE 147
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Match: ENSORLT00000043517.1 (pep primary_assembly:ASM223467v1:16:19117833:19123606:1 gene:ENSORLG00000022513.1 transcript:ENSORLT00000043517.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 1.247e-12
Identity = 47/147 (31.97%), Postives = 77/147 (52.38%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRH--------QKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDF-GEINDSFGVL 427
            MF+   +L    G F+ IWL AT+G K + ++D   V++   C +IM+YVL           K + SLYLSSQL +G+ V+YH++   LL +LQ +  + L       ++  D +R      D      VS++++  G ++  FGV+
Sbjct:    1 MFYYPAVLKRHSGSFSTIWLVATKGIK-VPRRDFLKVNVKSTCDDIMNYVLERVPPPAPGLPKPRFSLYLSSQLQYGVVVVYHRQCAILLEELQFIVTQLLKQRDTQKIDLPDHSRQPVLLSDA-----VSLMEETEGALDPLFGVM 141
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Match: rec8b (REC8 meiotic recombination protein [Source:NCBI gene;Acc:101160116])

HSP 1 Score: 66.6254 bits (161), Expect = 4.249e-11
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRH--------QKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQ 271
            MF+  ++L    G F+ +WLAATRG + + +K+L  V++   C  I+DY+            + + SLYLSSQL +G+ V+Y+K+   LL ++Q
Sbjct:    1 MFYYPNVLQRHTGCFSTVWLAATRGIQ-VHRKELVKVNVKRTCGAILDYITAQVPPPQPNQPRPRFSLYLSSQLQYGVVVVYYKQCGFLLEEIQ 93
[Close]
BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Match: rad21 (RAD21 cohesin complex component [Source:NCBI gene;Acc:100049255])

HSP 1 Score: 61.6178 bits (148), Expect = 1.606e-9
Identity = 61/204 (29.90%), Postives = 90/204 (44.12%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFN 628
             F +  ++ KRG    IWLAA   +K LTK  +   +L  +   I+       K+K++L  S  L  G+  IYH+K   LL D  + + K  + F    V+  + NR A      + +T+     DF +       L +L+      D+D+  Q   LNQ+R E+ITM E D G               NL LLQ+    TDF 
Sbjct:    1 MFYAHFVLSKRGPLAKIWLAA-HWDKKLTKAHVFECNLESSVESIIS-----PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAA----YNAITLPEEFHDFDQ------PLPDLD------DIDVAQQFT-LNQSRVEEITMRE-DVG---------------NLSLLQD----TDFG 161
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Match: rad21l1 (double-strand-break repair protein rad21-like protein 1 [Source:NCBI gene;Acc:101173147])

HSP 1 Score: 53.1434 bits (126), Expect = 7.270e-7
Identity = 90/370 (24.32%), Postives = 140/370 (37.84%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEM-HIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRK-TLIIDQTTTLSHQVIRDNMN 1120
             F + L   KRG    IWLAA   EK LTK  +   +L     EI+       K+K+ L  S  L  GL  IY +K   LL D      K    F      Q+D       GR +  +  +++ +DF           ++E  H   D+D+    A LNQ R E+IT+ E D+G N   N  D  +      +   L+ S        E +     D     ED+ +D +  +G  +E +                L EE  + + +   D       ++ N  + E P+  +T +  ++ V+ A+E                           V   P   KR   RK  L++D    LS+ VIR+ ++
Sbjct:    1 MFYTHLFTSKRGSLAKIWLAA-HWEKKLTKPHVFECNLETTVREILS-----PKMKVGLRTSGHLLIGLVRIYSRKAKYLLADCTIALGKISTAF---RPGQTDLCL----GRVEATVKEITLTEDFTAF--------DVELPHP-CDIDIPEDFA-LNQCRSEEITLKE-DFG-NGFLNLTDMGI------VSDSLVPSNTVLDRSFEGFAQH--DDAFGDEDKGLDLLDFLGMSSEPT---------------DLMEELTHESHESPNDLQNHTVAFEGNPTVTETPSPNQTTLLTNMDVAFALEP--------------------------VAITPNSEKRVGKRKRKLVVDHAKELSNDVIREQLS 296
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Match: rec8b (REC8 meiotic recombination protein [Source:NCBI gene;Acc:101160116])

HSP 1 Score: 51.6026 bits (122), Expect = 2.028e-6
Identity = 28/75 (37.33%), Postives = 45/75 (60.00%), Query Frame = 2 
Query:   71 LAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRH--------QKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQ 271
            LAATRG + + +K+L  V++   C  I+DY+            + + SLYLSSQL +G+ V+Y+K+   LL ++Q
Sbjct:    7 LAATRGIQ-VHRKELVKVNVKRTCGAILDYITAQVPPPQPNQPRPRFSLYLSSQLQYGVVVVYYKQCGFLLEEIQ 80
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BLAST of Meiotic recombination protein rec8 vs. Planmine SMEST
Match: SMESG000041612.1 (SMESG000041612.1)

HSP 1 Score: 1293.1 bits (3345), Expect = 0.000e+0
Identity = 627/627 (100.00%), Postives = 627/627 (100.00%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI 1894
            MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI
Sbjct:    1 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI 627
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BLAST of Meiotic recombination protein rec8 vs. Planmine SMEST
Match: SMESG000041612.1 (SMESG000041612.1)

HSP 1 Score: 1260.36 bits (3260), Expect = 0.000e+0
Identity = 616/627 (98.25%), Postives = 616/627 (98.25%), Query Frame = 2 
Query:   14 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI 1894
            MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFT        R   AKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI
Sbjct:    1 MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTC-------RCSIAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLGSTDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVDLDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDVKVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKTLIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSATNLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQETTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTLEENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEKGDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLRLGKYGKIQIFQENSLTEIFIGLPAREI 620
[Close]
BLAST of Meiotic recombination protein rec8 vs. Planmine SMEST
Match: SMESG000003065.1 (SMESG000003065.1)

HSP 1 Score: 49.6766 bits (117), Expect = 6.302e-6
Identity = 47/183 (25.68%), Postives = 82/183 (44.81%), Query Frame = 2 
Query:   17 FFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYVLRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNNVNQSDRNRGAKKGRDKH--NLTMVSILDDFGEINDSFGVLKNLENNHEGTDMDLTNQIAY---LNQARFEDITMMEYDYGQNNI 550
             F +  ++ K+G    IWLAA   +K LT+  +   ++  +   I++      K+KL+L  S  L  G+  I+ ++   LL+D  + + K  + F            GA    D H  N  + +I             L +  ++ E T  D+ +   Y   +NQ+R EDITM E ++G+ N+
Sbjct:    1 MFYAHFVLSKKGPLARIWLAA-HWDKKLTRSQVFETNITSSVEAILE-----PKVKLALRTSGHLLLGVVRIHSRQAKYLLSDCNEAFVKIKMAF----------RPGADLTEDNHRDNTALAAI------------TLSDNMHDFESTLADINDMDPYGIAVNQSRPEDITMRE-EFGEPNL 154
The following BLAST results are available for this feature:
BLAST of Meiotic recombination protein rec8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
REC81.400e-1036.36REC8 meiotic recombination protein [Source:HGNC Sy... [more]
REC81.400e-1036.36REC8 meiotic recombination protein [Source:HGNC Sy... [more]
REC81.400e-1036.36REC8 meiotic recombination protein [Source:HGNC Sy... [more]
REC81.400e-1036.36REC8 meiotic recombination protein [Source:HGNC Sy... [more]
RAD212.263e-930.00RAD21 cohesin complex component [Source:HGNC Symbo... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
coh-16.898e-928.11COHesin family [Source:UniProtKB/TrEMBL;Acc:A0A13... [more]
scc-15.280e-828.40Sister chromatid cohesion protein 1 [Source:UniPr... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
vtd3.387e-726.09gene:FBgn0260987 transcript:FBtr0113746[more]
vtd4.082e-726.09gene:FBgn0260987 transcript:FBtr0344093[more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rec8a2.406e-1639.60REC8 meiotic recombination protein a [Source:ZFIN;... [more]
rec8b1.275e-1231.90REC8 meiotic recombination protein b [Source:ZFIN;... [more]
rad21a2.166e-930.65RAD21 cohesin complex component a [Source:NCBI gen... [more]
rad21a2.166e-930.65RAD21 cohesin complex component a [Source:NCBI gen... [more]
rad21b2.581e-930.00RAD21 cohesin complex component b [Source:ZFIN;Acc... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mdh17.243e-1136.27malate dehydrogenase 1 [Source:Xenbase;Acc:XB-GENE... [more]
mdh18.334e-1136.27malate dehydrogenase 1 [Source:Xenbase;Acc:XB-GENE... [more]
RAD211.503e-930.00RAD21 cohesin complex component [Source:NCBI gene;... [more]
RAD211.654e-930.00RAD21 cohesin complex component [Source:NCBI gene;... [more]
RAD212.055e-930.00RAD21 cohesin complex component [Source:NCBI gene;... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Rec82.069e-1037.50REC8 meiotic recombination protein [Source:MGI Sym... [more]
Rad214.425e-1028.99RAD21 cohesin complex component [Source:MGI Symbol... [more]
Rad211.301e-930.00RAD21 cohesin complex component [Source:MGI Symbol... [more]
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BLAST of Meiotic recombination protein rec8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O95072|REC8_HUMAN6.725e-1036.36Meiotic recombination protein REC8 homolog OS=Homo... [more]
sp|Q8C5S7|REC8_MOUSE1.447e-937.50Meiotic recombination protein REC8 homolog OS=Mus ... [more]
sp|Q6AYJ4|REC8_RAT2.482e-938.30Meiotic recombination protein REC8 homolog OS=Ratt... [more]
sp|Q61550|RAD21_MOUSE9.101e-930.00Double-strand-break repair protein rad21 homolog O... [more]
sp|Q3SWX9|RAD21_BOVIN1.004e-830.00Double-strand-break repair protein rad21 homolog O... [more]
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BLAST of Meiotic recombination protein rec8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PXB25.286e-2741.14Meiotic recombination protein REC8 homolog (Fragme... [more]
A0A068Y5685.877e-2738.95Meiotic recombination protein rec8 OS=Echinococcus... [more]
A0A068X0T73.478e-2639.31Meiotic recombination protein rec8 OS=Echinococcus... [more]
A0A4S2M2B92.130e-2538.42Rad21_Rec8_N domain-containing protein OS=Opisthor... [more]
A0A4S2M2K62.440e-2538.42Uncharacterized protein OS=Opisthorchis felineus O... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
rad21b1.970e-930.00RAD21 cohesin complex component [Source:NCBI gene;... [more]
rad21a2.225e-930.11double-strand-break repair protein rad21 homolog [... [more]
rad21a2.225e-930.11double-strand-break repair protein rad21 homolog [... [more]
rad21a2.706e-930.11double-strand-break repair protein rad21 homolog [... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
RAD211.029e-929.24RAD21 cohesin complex component [Source:HGNC Symbo... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO383948.384e-725.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Meiotic recombination protein rec8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000043517.11.247e-1231.97pep primary_assembly:ASM223467v1:16:19117833:19123... [more]
rec8b4.249e-1136.17REC8 meiotic recombination protein [Source:NCBI ge... [more]
rad211.606e-929.90RAD21 cohesin complex component [Source:NCBI gene;... [more]
rad21l17.270e-724.32double-strand-break repair protein rad21-like prot... [more]
rec8b2.028e-637.33REC8 meiotic recombination protein [Source:NCBI ge... [more]
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BLAST of Meiotic recombination protein rec8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000041612.10.000e+0100.00SMESG000041612.1[more]
SMESG000041612.10.000e+098.25SMESG000041612.1[more]
SMESG000003065.16.302e-625.68SMESG000003065.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001230 ID=SMED30001230|Name=Meiotic recombination protein rec8|organism=Schmidtea mediterranea sexual|type=transcript|length=1980bp
AATTTAAAAAAAAATGTTTTTCAGTTCTGATTTGCTAATTTTTAAAAGAG
GAAAATTTAACTTAATTTGGTTAGCTGCCACTAGAGGCGAAAAATATTTG
ACTAAAAAAGATTTAAATATGGTGGATTTACACCATGCATGTTCTGAGAT
CATGGATTATGTTTTGCGTCATCAAAAAATCAAACTTTCTTTGTATTTAT
CATCTCAGTTGACGTTTGGTTTGTGTGTTATATATCACAAAAAAATTGAT
AAATTACTTAATGATCTCCAAGACTTATACAAAAAGTCATTAGTTACTTT
TACAGTTAATAATGTAAATCAATCAGATAGAAATCGAGGAGCAAAAAAAG
GAAGAGATAAACACAATCTTACTATGGTGAGCATTTTGGATGATTTTGGC
GAAATCAATGATAGCTTTGGAGTTCTTAAAAATTTAGAAAACAATCACGA
AGGGACTGATATGGACTTAACTAATCAAATAGCTTATTTAAACCAAGCAA
GATTTGAAGATATAACAATGATGGAATATGATTATGGACAAAACAACATA
CGAAATCAACTTGACAATGATTTGGAACCAATGAATTTAGAATTATTGCA
AGAATTATTAGGATCCACGGATTTTAATAAAAATGATTTGGAAACATATC
TTAATCAACCGTTTGATGTGCAGATTGAAAAAGAAGATGAAAAAATCGAC
GAAATGCACATTGGAAACAAAACAGAACAGTCAGTGCAAGAAAAAATTGA
ATTTGAGGTAGATTTAGATAAAACTTTACCGCTTTGCGAGGAAAAAGAAA
ATAACGCCGACAAAATGGAAACGGATGCTAATTTAGAACAAGCAGAATAT
GATAGAAATCACGATTTGAATGAACGTCCAACGGATGCTGAAACATTGAT
AAGAAACGATGTTAAAGTGAGTTGTGCCATCGAGGAAGTGGAAAAAGTGA
ACTTGGTAGGTTCTGATTCCTATATAGAACTTCAGTATCCTCGTAAACAT
ACACTTCCTAAACAAGTAACCACTGCTCCGAAAATATTGAAACGTAAAGC
TAATAGAAAAACATTAATAATCGATCAAACAACGACATTAAGCCATCAAG
TGATTCGAGACAACATGAACAAAAAGGCATTTGGTTTAGTTGATAAAAAT
ATGTTATTTCCTAACGCATATGTCACAAAGTCATTGAAAGCTCAAATTGC
GTGTTCAGCCACAAATCTGTTCGAATTTCCCGGATGCTATAATACATTGT
TTTCTCAAAAATTGTTACGTTTATGGATGGATCGAAAAGATGCCTGTAAA
TCCGCAAAATCGCCTTTCATTGACTATGAAACTTTTCCGAATTTTGAATT
GAATAACCAGGAAACTACAAATCTCAATTTTTCTGAATTATCTATCGAAA
AATTTCGTGAAGCTAGTTCGTATAACATGAACATTCCAGTCGATTCTTTT
ACTTTAGGCAGTGATGGTATTCAGAAAAGCATTCAACAAAGTTTTGAAGT
CGATAGGACTTTGGAGGAAAATAATCCCTATGTGCCTGAAATTATCGATG
AAATCGTACCTAATTCCTTAGAAAAATCGATGATGCCGATTATCGAGGAA
GATTTCAATTCCAAATTTTGCGTTAATAATGAAATTCCACATGAAACCAA
AATTCTTGAAAAGGGAGATATATGGCGAGTCCTTCAAGCGCTATTAAAAA
CAGAGCTCAACACATCGAAAAATTGGAATGATGTTAGAGTAGCATTCACA
GATTTATGTCCAAAACATTCAACGAAGAAAACTGCAGCTATGGTGTTTCT
AACTTTACTACGGTTAGGGAAATACGGAAAAATCCAAATTTTTCAAGAAA
ATTCTTTGACGGAGATTTTTATTGGTTTACCAGCAAGAGAAATCTAATTT
TATTATTTAGTTATATTTGATTATTGTTGATAGTTGAGTTTTGTTAACAT
TTTGTTGATTTGTTTACTTTTTGATTCTGT
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protein sequence of SMED30001230-orf-1

>SMED30001230-orf-1 ID=SMED30001230-orf-1|Name=SMED30001230-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=628bp
MFFSSDLLIFKRGKFNLIWLAATRGEKYLTKKDLNMVDLHHACSEIMDYV
LRHQKIKLSLYLSSQLTFGLCVIYHKKIDKLLNDLQDLYKKSLVTFTVNN
VNQSDRNRGAKKGRDKHNLTMVSILDDFGEINDSFGVLKNLENNHEGTDM
DLTNQIAYLNQARFEDITMMEYDYGQNNIRNQLDNDLEPMNLELLQELLG
STDFNKNDLETYLNQPFDVQIEKEDEKIDEMHIGNKTEQSVQEKIEFEVD
LDKTLPLCEEKENNADKMETDANLEQAEYDRNHDLNERPTDAETLIRNDV
KVSCAIEEVEKVNLVGSDSYIELQYPRKHTLPKQVTTAPKILKRKANRKT
LIIDQTTTLSHQVIRDNMNKKAFGLVDKNMLFPNAYVTKSLKAQIACSAT
NLFEFPGCYNTLFSQKLLRLWMDRKDACKSAKSPFIDYETFPNFELNNQE
TTNLNFSELSIEKFREASSYNMNIPVDSFTLGSDGIQKSIQQSFEVDRTL
EENNPYVPEIIDEIVPNSLEKSMMPIIEEDFNSKFCVNNEIPHETKILEK
GDIWRVLQALLKTELNTSKNWNDVRVAFTDLCPKHSTKKTAAMVFLTLLR
LGKYGKIQIFQENSLTEIFIGLPAREI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0007062sister chromatid cohesion
Vocabulary: cellular component
TermDefinition
GO:0008278cohesin complex
GO:0000228nuclear chromosome
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0002109X1 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR039781Rad21/Rec8-like
IPR023093Rad21/Rec8_C
IPR006910Rad21_Rec8_N
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 258..278
NoneNo IPR availablePANTHERPTHR12585:SF29FI11703Pcoord: 1..620
IPR006910Rad21/Rec8-like protein, N-terminalPFAMPF04825Rad21_Rec8_Ncoord: 1..108
e-value: 8.5E-19
score: 67.8
IPR039781Rad21/Rec8-like proteinPANTHERPTHR12585SCC1 / RAD21 FAMILY MEMBERcoord: 1..620