Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30001161 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK24 (serine/threonine kinase 24 [Source:HGNC Symbol;Acc:HGNC:11403]) HSP 1 Score: 169.088 bits (427), Expect = 1.723e-46 Identity = 97/260 (37.31%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF+L
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIL 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK24 (serine/threonine kinase 24 [Source:HGNC Symbol;Acc:HGNC:11403]) HSP 1 Score: 169.088 bits (427), Expect = 2.414e-46 Identity = 97/260 (37.31%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF+L
Sbjct: 31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIL 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 154.836 bits (390), Expect = 1.718e-41 Identity = 88/260 (33.85%), Postives = 148/260 (56.92%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLE++G+GSFG V+K ++ +++V A+K++ L+ A + + I + + K+YGS L + I E++ GS D++ + G Q A +E L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P + PM + I NP + + + T F K+ + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL-RAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL-VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 154.836 bits (390), Expect = 2.367e-41 Identity = 88/260 (33.85%), Postives = 148/260 (56.92%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLE++G+GSFG V+K ++ +++V A+K++ L+ A + + I + + K+YGS L + I E++ GS D++ + G Q A +E L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P + PM + I NP + + + T F K+ + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL-RAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL-VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 154.451 bits (389), Expect = 7.445e-41 Identity = 87/259 (33.59%), Postives = 148/259 (57.14%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPN-GTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K + ++ A+K V ++ + + + ++ + + H +VK+YGS + + I E+ GS+ D+I +N LT + A + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG+T +EM G P + + PM I I P + P ++ + F K VK+ R A LL+ F+ + K
Sbjct: 30 FDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEIIKEISIMQQCDSPH--VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAK 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 146.362 bits (368), Expect = 1.584e-37 Identity = 84/272 (30.88%), Postives = 148/272 (54.41%), Query Frame = 1
Query: 37 NYYTYF*AMDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
N+ + +D + + K E++G+GSFG V+K ++ + +V A+K++ L+ A + + I + + + K++GS L + I E++ GS D + K+G L A RE L+GL++LH IHRDIK N+L++EH +K+ DFG++ + ++V TF G+ ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I P ++ + F ++ K+ +RP A LL+ +F+ K
Sbjct: 5 NFGSEIEKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL-TETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 146.747 bits (369), Expect = 1.634e-37 Identity = 84/268 (31.34%), Postives = 146/268 (54.48%), Query Frame = 1
Query: 49 YF*AMDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
Y +D + + K E++G+GSFG V+K ++ + +V A+K++ L+ A + + I + + + K++GS L + I E++ GS D + K+G L A RE L+GL++LH IHRDIK N+L++EH +K+ DFG++ + ++V TF G+ ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I P ++ + F ++ K+ +RP A LL+ +F+ K
Sbjct: 24 YIQKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL-TETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 145.976 bits (367), Expect = 2.237e-37 Identity = 83/264 (31.44%), Postives = 145/264 (54.92%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
+D + + K E++G+GSFG V+K ++ + +V A+K++ L+ A + + I + + + K++GS L + I E++ GS D + K+G L A RE L+GL++LH IHRDIK N+L++EH +K+ DFG++ + ++V TF G+ ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I P ++ + F ++ K+ +RP A LL+ +F+ K
Sbjct: 8 LDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL-TETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 269
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 145.976 bits (367), Expect = 4.721e-37 Identity = 83/264 (31.44%), Postives = 145/264 (54.92%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
+D + + K E++G+GSFG V+K ++ + +V A+K++ L+ A + + I + + + K++GS L + I E++ GS D + K+G L A RE L+GL++LH IHRDIK N+L++EH +K+ DFG++ + ++V TF G+ ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I P ++ + F ++ K+ +RP A LL+ +F+ K
Sbjct: 178 LDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDSQYVTKYFGSFLKGSKLWIIMEYLGGGSALD-LTKSGKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQL-TETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQFIKRAK 439
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8]) HSP 1 Score: 139.043 bits (349), Expect = 4.804e-36 Identity = 82/253 (32.41%), Postives = 138/253 (54.55%), Query Frame = 1
Query: 94 KVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNG-TNELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
K+G+GS+G+V K + + S V A+K V +D + + + ++ + + + +VK+YGS + I E+ GS+ D++ + L+ ++ + R++L+GL +LH+ IHRDIK GNILL KL DFG++ + + ++ +T GT ++MAPE+IE+ GY + DIW+LG+T +EM G P + + PM I I P K P ++E + F + +K R A L F+ N
Sbjct: 40 KLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEIIKEISIMQQCKSKY--VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFIKNA 289
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0340454) HSP 1 Score: 155.606 bits (392), Expect = 4.995e-40 Identity = 96/263 (36.50%), Postives = 146/263 (55.51%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELSY----FFKLVFVKNAASRPKARDLLRCKFL 837
EYE ++K+G G++G V+K S ++ A+KV+ L+ + +I + +I+ H ++ +YGS L + I EF GSL+D+ G LT Q A RE+L+GL++LH +HRDIK NILLTE+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ DIWA G+T +E+ P L PM LF+++ F P + N ++ S F K KN RP A LL+ F+
Sbjct: 25 EYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQI-TATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL---NNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0340456) HSP 1 Score: 155.606 bits (392), Expect = 5.134e-40 Identity = 96/263 (36.50%), Postives = 146/263 (55.51%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELS----YFFKLVFVKNAASRPKARDLLRCKFL 837
EYE ++K+G G++G V+K S ++ A+KV+ L+ + +I + +I+ H ++ +YGS L + I EF GSL+D+ G LT Q A RE+L+GL++LH +HRDIK NILLTE+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ DIWA G+T +E+ P L PM LF+++ F P + N ++ S F K KN RP A LL+ F+
Sbjct: 25 EYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQI-TATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL---NNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0086503) HSP 1 Score: 155.606 bits (392), Expect = 5.213e-40 Identity = 96/263 (36.50%), Postives = 146/263 (55.51%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELS----YFFKLVFVKNAASRPKARDLLRCKFL 837
EYE ++K+G G++G V+K S ++ A+KV+ L+ + +I + +I+ H ++ +YGS L + I EF GSL+D+ G LT Q A RE+L+GL++LH +HRDIK NILLTE+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ DIWA G+T +E+ P L PM LF+++ F P + N ++ S F K KN RP A LL+ F+
Sbjct: 25 EYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQI-TATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL---NNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0086504) HSP 1 Score: 155.606 bits (392), Expect = 6.943e-40 Identity = 96/263 (36.50%), Postives = 146/263 (55.51%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELS----YFFKLVFVKNAASRPKARDLLRCKFL 837
EYE ++K+G G++G V+K S ++ A+KV+ L+ + +I + +I+ H ++ +YGS L + I EF GSL+D+ G LT Q A RE+L+GL++LH +HRDIK NILLTE+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ DIWA G+T +E+ P L PM LF+++ F P + N ++ S F K KN RP A LL+ F+
Sbjct: 25 EYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQI-TATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL---NNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: hppy (gene:FBgn0263395 transcript:FBtr0340455) HSP 1 Score: 155.221 bits (391), Expect = 6.968e-40 Identity = 96/263 (36.50%), Postives = 146/263 (55.51%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELS----YFFKLVFVKNAASRPKARDLLRCKFL 837
EYE ++K+G G++G V+K S ++ A+KV+ L+ + +I + +I+ H ++ +YGS L + I EF GSL+D+ G LT Q A RE+L+GL++LH +HRDIK NILLTE+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ DIWA G+T +E+ P L PM LF+++ F P + N ++ S F K KN RP A LL+ F+
Sbjct: 25 EYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQI-TATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL---NNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841]) HSP 1 Score: 159.844 bits (403), Expect = 2.850e-43 Identity = 93/261 (35.63%), Postives = 149/261 (57.09%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLE++G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L D + I E++ GS D++ + G+L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N L F + K + RP A++LL+ K ++
Sbjct: 7 DPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 264
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk24b (serine/threonine kinase 24b (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-040426-2841]) HSP 1 Score: 159.844 bits (403), Expect = 3.295e-43 Identity = 93/261 (35.63%), Postives = 149/261 (57.09%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLE++G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L D + I E++ GS D++ + G+L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N L F + K + RP A++LL+ K ++
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGSLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map4k6 (mitogen-activated protein kinase kinase kinase kinase 6 [Source:ZFIN;Acc:ZDB-GENE-060512-339]) HSP 1 Score: 162.925 bits (411), Expect = 2.283e-42 Identity = 96/262 (36.64%), Postives = 148/262 (56.49%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNG-TNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
+YE + ++G G++G V+K + + A+KVV LD S I + + + H+ +V ++GS L + + I EF GSL+D+ + G L +Q A +RE+L+GL LH+ +HRDIK NILLTE +KL DFG++ + N SV +F GT Y+MAPE+ +EKK GY+ DIWA+G+T +E+ P L PM L +++ +F P +K N + E F K+ KN RP A +L+ F++
Sbjct: 14 DYELIHRIGSGTYGDVFKARSIKTSVIAAIKVVKLDPGDDISSIQNEITMMKDCTHKNIVAYFGSYLRNNKLWICMEFCGGGSLQDIYHVTGPLKERQIAYVSRETLQGLHHLHQTGKMHRDIKGANILLTERGDVKLADFGVAAEI-NASVAKRKSFIGTPYWMAPEVAAVEKKGGYNQLCDIWAVGITAIELAELQPPMFDLHPMRALMLMSKSSFQPPKLKEKNKWSTEFHSFIKMALTKNPRKRPTAEKILQHAFVMQ 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk24a (serine/threonine kinase 24a (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-070424-52]) HSP 1 Score: 155.221 bits (391), Expect = 9.752e-42 Identity = 91/261 (34.87%), Postives = 146/261 (55.94%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
+D + + KLE++G+GSFG V+K ++ ++KV A+K++ L+ A + + I + K++GS L D + I E++ GS D++ G L A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N L F K+ RP A++LL+ K ++
Sbjct: 11 LDPEKLFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEVEDIQQEITVLSQCDSLFITKYFGSYLKDTKLWIIMEYLGGGSALDLLGP-GALDETHIATILREILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSEYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKENPPTLE-GNYNKALKEFVDACLNKDPNFRPTAKELLKHKLIV 268
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: stk3 (serine/threonine kinase 3 (STE20 homolog, yeast) [Source:NCBI gene;Acc:324125]) HSP 1 Score: 155.992 bits (393), Expect = 2.156e-41 Identity = 89/259 (34.36%), Postives = 150/259 (57.92%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V ++ + + + ++ + + + +VK+YGS + + I E+ GS+ D+I +N LT + A + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG+T +EM G P + + PM I I P + P + +++ + F K VKN R A LL+ F++ K
Sbjct: 26 FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPY--VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATVLKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPEHWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIVGAK 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: slc39a7 (solute carrier family 39 member 7 [Source:Xenbase;Acc:XB-GENE-492963]) HSP 1 Score: 169.474 bits (428), Expect = 8.595e-47 Identity = 96/262 (36.64%), Postives = 153/262 (58.40%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF++ +
Sbjct: 17 DPEELFRKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKGLKEFVEACLNKEPSFRPSAKELLKHKFIMRS 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: slc39a7 (solute carrier family 39 member 7 [Source:Xenbase;Acc:XB-GENE-492963]) HSP 1 Score: 169.474 bits (428), Expect = 9.337e-47 Identity = 96/262 (36.64%), Postives = 153/262 (58.40%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF++ +
Sbjct: 19 DPEELFRKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKGLKEFVEACLNKEPSFRPSAKELLKHKFIMRS 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 163.696 bits (413), Expect = 5.136e-45 Identity = 93/262 (35.50%), Postives = 148/262 (56.49%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
MD + + KLE++G+GSFG V+K +E S++V A+K++ L+ A + + I + + ++YGS L + I E++ GS D++ K G L A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y DIW+LG+T +E+ G+P + L PM + I NP ++ + F + K+ SRP AR+LL+ +F+L
Sbjct: 1 MDPERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ-GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFILR 259
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 163.696 bits (413), Expect = 7.505e-45 Identity = 93/262 (35.50%), Postives = 148/262 (56.49%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
MD + + KLE++G+GSFG V+K +E S++V A+K++ L+ A + + I + + ++YGS L + I E++ GS D++ K G L A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y DIW+LG+T +E+ G+P + L PM + I NP ++ + F + K+ SRP AR+LL+ +F+L
Sbjct: 13 MDPERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ-GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFILR 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 163.696 bits (413), Expect = 8.287e-45 Identity = 93/262 (35.50%), Postives = 148/262 (56.49%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
MD + + KLE++G+GSFG V+K +E S++V A+K++ L+ A + + I + + ++YGS L + I E++ GS D++ K G L A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y DIW+LG+T +E+ G+P + L PM + I NP ++ + F + K+ SRP AR+LL+ +F+L
Sbjct: 1 MDPERLFTKLERIGKGSFGEVYKGIENRSKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYYGSYLKGSKLWIIMEYLGGGSALDLL-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPYSDLHPMRVLFLIPKNNPPSLQ-GQYSKPFKDFVEACLNKDPRSRPTARELLKHRFILR 259
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk24 (serine/threonine kinase 24 [Source:MGI Symbol;Acc:MGI:2385007]) HSP 1 Score: 167.162 bits (422), Expect = 6.525e-46 Identity = 96/260 (36.92%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFII 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 155.221 bits (391), Expect = 6.475e-42 Identity = 89/260 (34.23%), Postives = 148/260 (56.92%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLE++G+GSFG V+K ++ +++V A+K++ L+ A + + I + + K+YGS L + I E++ GS D++ + G Q A +E L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P + PM + I NP + I + T F K+ + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL-RAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL-IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 155.221 bits (391), Expect = 1.052e-41 Identity = 89/260 (34.23%), Postives = 148/260 (56.92%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLE++G+GSFG V+K ++ +++V A+K++ L+ A + + I + + K+YGS L + I E++ GS D++ + G Q A +E L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P + PM + I NP + I + T F K+ + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLL-RAGPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL-IGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIV 275
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map4k3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:MGI Symbol;Acc:MGI:2154405]) HSP 1 Score: 158.688 bits (400), Expect = 5.505e-41 Identity = 90/260 (34.62%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
++E ++++G G++G V+K ++ ++ A+KV+ L+ +++ + +I+ + H +V ++GS L + I EF GSL+D+ + G L+ Q A +RE+L+GL +LH +HRDIK NILLT++ H+KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ D+WA+G+T +E+ P L PM LF++ NF P +K +N +F K+ KN RP A LL+ F+
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQI-TATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPFV 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map4k3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:MGI Symbol;Acc:MGI:2154405]) HSP 1 Score: 158.688 bits (400), Expect = 5.765e-41 Identity = 90/260 (34.62%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
++E ++++G G++G V+K ++ ++ A+KV+ L+ +++ + +I+ + H +V ++GS L + I EF GSL+D+ + G L+ Q A +RE+L+GL +LH +HRDIK NILLT++ H+KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ D+WA+G+T +E+ P L PM LF++ NF P +K +N +F K+ KN RP A LL+ F+
Sbjct: 15 DFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQI-TATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPFV 273
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y6E0|STK24_HUMAN (Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1) HSP 1 Score: 169.088 bits (427), Expect = 1.159e-45 Identity = 97/260 (37.31%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF+L
Sbjct: 31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFIL 287
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99KH8|STK24_MOUSE (Serine/threonine-protein kinase 24 OS=Mus musculus OX=10090 GN=Stk24 PE=1 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 4.564e-45 Identity = 96/260 (36.92%), Postives = 152/260 (58.46%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFII 275
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|B0LT89|STK24_RAT (Serine/threonine-protein kinase 24 OS=Rattus norvegicus OX=10116 GN=Stk24 PE=2 SV=1) HSP 1 Score: 165.236 bits (417), Expect = 2.198e-44 Identity = 95/261 (36.40%), Postives = 152/261 (58.24%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ + G L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ + + L F + K + RP A++LL+ KF++
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLL-EPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GSYSRPLKEFVEACLNKEPSFRPTAKELLKHKFIIR 276
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6IP06|STK3_XENLA (Serine/threonine-protein kinase 3 OS=Xenopus laevis OX=8355 GN=stk3 PE=2 SV=1) HSP 1 Score: 161.77 bits (408), Expect = 1.610e-42 Identity = 93/259 (35.91%), Postives = 150/259 (57.92%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPN-GTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V ++ + + + ++ + +++ +VK+YGS + + I E+ GS+ D+I +N LT + A R +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG+T +EM G P + + PM I I P + P T+E + F K VKN R A LL+ F+ N K
Sbjct: 26 FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSHY--VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILRSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKKCLVKNPEQRATATQLLQHPFIKNAK 281
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q802A6|STK4_SQUAC (Serine/threonine-protein kinase 3/4 OS=Squalus acanthias OX=7797 GN=STK4 PE=2 SV=1) HSP 1 Score: 161.384 bits (407), Expect = 2.084e-42 Identity = 92/259 (35.52%), Postives = 149/259 (57.53%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPN-GTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V ++ + + + ++ + + H +VK+YGS + + I E+ GS+ D+I +N LT + A + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG++ +EM G P + + PM I I P + P T+E + F K VKN R A LL+ F+ N K
Sbjct: 32 FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPH--VVKYYGSYFKNTDLWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGISAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDFVKQCLVKNPEQRAAATQLLQHPFIKNAK 287
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A210PFZ5 (Mitogen-activated protein kinase kinase kinase 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT24565 PE=4 SV=1) HSP 1 Score: 172.555 bits (436), Expect = 7.020e-45 Identity = 98/261 (37.55%), Postives = 147/261 (56.32%), Query Frame = 1
Query: 73 AEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-----NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENK-SVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSY-FFKLVFVKNAASRPKARDLLRCKF 834
+ ++K ++G GSFG V+ C +K S + A+K V L+ ++ + EI HER+V ++G + IF E++ GS++D + K G LT T KYTR+ LEGL FLH++ ++HRDIK N+L +IKL DFG SK + S +F GT ++MAPE+I +GY D+W+LG TVVEM++G P + L M I I + ++P ++E S F +L F +N RP + DLLR +F
Sbjct: 128 SNWKKGHRLGSGSFGEVFVCYDKDSGRELAVKQVNLNQMNAETSKEVRALENEIQLLRNFQHERIVSYFGCHQDHSILSIFMEYMPGGSIKDELAKYGPLTEGVTRKYTRQMLEGLAFLHKNVIVHRDIKAANVLRDLQGNIKLADFGASKRLHTICSATGFKSFVGTPHYMAPEVINGEGYGRKADVWSLGCTVVEMISGKPPWSELESMAAIYKIATAERPEFELPQRSSEFSREFLRLTFRRNPLERPSSEDLLRHRF 388
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1Y1YUP7 (Sterile 20-like kinase 3 OS=Basidiobolus meristosporus CBS 931.73 OX=1314790 GN=K493DRAFT_323427 PE=4 SV=1) HSP 1 Score: 170.629 bits (431), Expect = 7.344e-45 Identity = 97/263 (36.88%), Postives = 148/263 (56.27%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
D D Y LEK+G GSFGTV+K + S+++ A+K + L+ A + I N + + ++Y S + F + I E+++ GS D++ K G+ A RE L GLD+LH IHRDIKC NILL+E ++KL DFG++ + ++ TF GT ++MAPE+I++ GY S DIW+LG+T +EM G P F PM + I P ++ N ++E F L KN + RP A++LL+ F+ N++
Sbjct: 36 DPDKIYTVLEKLGSGSFGTVYKGIHNDSKQLVAIKKIDLETAEDDITDIQQEIALLSQCNSDYITRYYHSYIKGFKLWIVMEYMSGGSCLDLL-KPGSFPEPLIAVTVRELLMGLDYLHSEGKIHRDIKCANILLSESGNVKLADFGVAAQLAHQKS-QRRTFVGTPFWMAPEVIQQTGYDSKADIWSLGITAIEMAQGQPPFADHHPMRVLFMIPKNKPPVLE-GNFSSEFKDFVSLCLTKNPSERPSAKELLKHPFINNSR 295
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A093CQH0 (Serine/threonine-protein kinase 24 (Fragment) OS=Tauraco erythrolophus OX=121530 GN=N340_01032 PE=4 SV=1) HSP 1 Score: 169.474 bits (428), Expect = 7.693e-45 Identity = 97/261 (37.16%), Postives = 153/261 (58.62%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ K G+L Q A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ KF+L
Sbjct: 3 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLV-KPGSLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNFSKSLKEFVEACLNKDPSFRPTAKELLKHKFILR 260
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A093T543 (Serine/threonine-protein kinase 24 (Fragment) OS=Phalacrocorax carbo OX=9209 GN=N336_12566 PE=4 SV=1) HSP 1 Score: 169.474 bits (428), Expect = 7.693e-45 Identity = 97/261 (37.16%), Postives = 153/261 (58.62%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ K G+L Q A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ KF+L
Sbjct: 3 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLV-KPGSLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNFSKSLKEFVEACLNKDPSFRPTAKELLKHKFILR 260
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A091SC89 (Serine/threonine-protein kinase 24 (Fragment) OS=Nestor notabilis OX=176057 GN=N333_00612 PE=4 SV=1) HSP 1 Score: 172.17 bits (435), Expect = 1.019e-44 Identity = 98/260 (37.69%), Postives = 154/260 (59.23%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I + + K+YGS L D + I E++ GS D++ K G+L Q A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ KF+L
Sbjct: 3 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLV-KPGSLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNFSKSLKEFVEACLNKDPSFRPTAKELLKHKFIL 259
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk24b (serine/threonine-protein kinase 24-like [Source:NCBI gene;Acc:103028447]) HSP 1 Score: 157.918 bits (398), Expect = 1.231e-42 Identity = 92/261 (35.25%), Postives = 148/261 (56.70%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLE++G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ K ++
Sbjct: 19 DPEQLFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-EPGALDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000008518.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:14507502:14520436:1 gene:ENSAMXG00000008289.2 transcript:ENSAMXT00000008518.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 155.606 bits (392), Expect = 3.909e-42 Identity = 93/261 (35.63%), Postives = 147/261 (56.32%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
D + + KLEK+G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N L F + K + RP A++LL+ K ++
Sbjct: 16 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE-GNYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk3 (serine/threonine kinase 3 [Source:NCBI gene;Acc:103027492]) HSP 1 Score: 155.606 bits (392), Expect = 3.060e-41 Identity = 89/259 (34.36%), Postives = 149/259 (57.53%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPN-GTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V ++ + + + ++ + + + +VK+YGS + + I E+ GS+ D+I +N LT + A + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG+T +EM G P + + PM I I P + P +++ + F K VKN R A LL+ F+ + K
Sbjct: 26 FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPY--VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFITSAK 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk24b (serine/threonine-protein kinase 24-like [Source:NCBI gene;Acc:103028447]) HSP 1 Score: 153.68 bits (387), Expect = 3.068e-41 Identity = 89/252 (35.32%), Postives = 143/252 (56.75%), Query Frame = 1
Query: 91 EKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
E++G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K + RP A++LL+ K ++
Sbjct: 1 ERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKGTKLWIIMEYLGGGSALDLL-EPGALDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 249
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: stk25a (serine/threonine-protein kinase 25 [Source:NCBI gene;Acc:103021644]) HSP 1 Score: 152.91 bits (385), Expect = 7.960e-41 Identity = 91/262 (34.73%), Postives = 147/262 (56.11%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSY--FFKLVFVKNAASRPKARDLLRCKFL 837
+D + + KLE++G+GSFG V+K + +++V A+K++ L+ A + + I V K++GS L + I E++ GS D++ K G L A RE L+GLD+LH IHRDIK N+LL+EH +KL DFG++ + + + N TF GT ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I NP ++ G+ ++ F + K+ RP A++LL+ KF+
Sbjct: 14 LDPEQYFTKLERIGKGSFGEVYKGINNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYFGSYLKSTKLWIIMEYLGGGSALDML-KPGPLEEAYIATILREILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPTLE---GSYSKAFKDFVEACLNKDPRFRPTAKELLKHKFI 270
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 150.984 bits (380), Expect = 1.349e-39 Identity = 91/266 (34.21%), Postives = 143/266 (53.76%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXX-----XXXXXXNHERLVKFYG--SKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSK-----CVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
+++ + +GQG+FG V+ C + + + A+K V D +++ L + HER+V+++G ++ IF E++ GS++D + G LT T KYTR+ LEG+ FLH + ++HRDIK NIL ++KL DFG SK C + ++ + GT Y+M+PE+I +GY DIW++G TVVEMLT P + M I I P D ++P + + + +FV+ A RP A DLLR F+
Sbjct: 359 WQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPGSVETSKEVNALECEIQLLKNLQHERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAM---RSVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIAT-QPTDPRLPLHASEHARDLLRRIFVE-AKLRPSAEDLLRHPFV 619
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6865]) HSP 1 Score: 149.828 bits (377), Expect = 9.436e-39 Identity = 87/258 (33.72%), Postives = 145/258 (56.20%), Query Frame = 1
Query: 67 IDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELSY-FFKLVFVKNAASRPKARDLL 822
+ ++E E++G G++G V K + ++ A+K++ L+ S+I + +++ + H +V +YGS L + I E GSL+D+ + G LT +Q A TRE+L+GL +LH +HRDIK NILLT+ +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ D+WA+G+T +E+ P L PM LF+++ F P ++ + + + F K+ KN RP A +L
Sbjct: 10 LQEDFELAERLGSGTYGDVHKARNVQTGELVAIKIIKLEPGDDFSVIQQEIVMMKECKHTNIVAYYGSYLRHDKLWICMEHCGGGSLQDIYHVTGPLTERQIAYVTRETLQGLAYLHSEGKMHRDIKGANILLTDDGDVKLADFGVSAQI-TATIAKRKSFIGTPYWMAPEVAAVERKGGYNHQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSGFQPPKLRDKQKWSPVFHNFIKMALTKNPKKRPTAEKML 266
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 144.436 bits (363), Expect = 2.098e-38 Identity = 89/264 (33.71%), Postives = 144/264 (54.55%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIK--CGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
D + + K E++G+GSFG V+K ++ +++V A+K++ L+ A + + I + + ++GS L + I E++ GS D+I K G L Q A RE L+GLD+LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y DIW+LG+T +E+ G+P L PM + I NP ++ N + F K+ RP A++LL+ KF+ +
Sbjct: 21 DPEELFTKQERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTHYFGSYLKGTKLWIIMEYLGGGSALDLI-KPGPLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEG-NYSKAFKEFVDSCLNKDPQFRPTAKELLKHKFIQRS 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: pak4 (p21 protein (Cdc42/Rac)-activated kinase 4 [Source:ZFIN;Acc:ZDB-GENE-040704-69]) HSP 1 Score: 139.043 bits (349), Expect = 2.373e-35 Identity = 88/260 (33.85%), Postives = 138/260 (53.08%), Query Frame = 1
Query: 73 AEY-EKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIK-IPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
+EY E K+G+GS G V V++ S + A+K + L + L+ +++ +HE +V Y S LV + + EF+ G+L D++ + +Q A L L +LH VIHRDIK +ILLT IKL+DFG V +K V + GT Y+MAPE+I + Y +D+W+LG+ V+EM+ G+P + + PP+ + I + P +K I + L F + V++ A R A +LL+ FL N
Sbjct: 416 SEYLENFIKIGEGSTGVVCLAVDRRSGRQVAVKKMHLRKQQRRELLFNEVVIMREYHHENVVDMYNSYLVADELWVVMEFLEGGALTDIVTHT-RMNEEQIATVCVSVLRALAYLHGQGVIHRDIKSDSILLTADGRIKLSDFGFCAQV-SKEVTRRKSLVGTPYWMAPEVISRLPYGPEVDVWSLGIMVIEMVDGEPPYFNEPPLQAMRRIRDNVPPKMKNIQKASPLLRGFLDQMLVRDPALRATALELLQHPFLQNA 673
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010511.1 (pep scaffold:Pmarinus_7.0:GL476756:358747:414819:1 gene:ENSPMAG00000009510.1 transcript:ENSPMAT00000010511.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 136.732 bits (343), Expect = 2.257e-34 Identity = 84/240 (35.00%), Postives = 135/240 (56.25%), Query Frame = 1
Query: 142 SSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
S + A+KV+ L+ ++I + +I+ + H +V ++GS L + I E+ GSL+D+ + G L+ +Q A +RE+L+GL +LH +HRDIK NILLT+H +KL DFG+S + ++ +F GT Y+MAPE+ +E+K GY+ D+WA+G+T +E+ P L PM LF+++ NF P +K + F K +KN RP A LL+ F++
Sbjct: 7 QSGALSAIKVIKLESGDDFTVIQQEIIMMQECQHINIVAYFGSYLRWDKLWICMEYCGGGSLQDIYHVTGPLSERQIAYVSRETLKGLAYLHSKCKMHRDIKGANILLTDHGEVKLADFGVSAQI-TATIAKRMSFIGTPYWMAPEVAAVERKGGYNQQCDVWAVGITAIELAELQPPMFDLHPMRALFLMSKSNFQPPRLKDKVKWSGIFHNFIKQSLIKNPKKRPTADKLLQDPFVIQ 245
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 151.369 bits (381), Expect = 2.220e-39 Identity = 92/260 (35.38%), Postives = 143/260 (55.00%), Query Frame = 1
Query: 58 AMDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGN-LTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILN---FNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLR 825
A + +Y + +G+GS+G V+K + K + +V A+K V+ + + I + L + NH +VK++G + + I E+ GSLR +I+++ L+ ++ Y ++L GL +LH VIHRDIK NILL+ + +KL DFG+S V + ++ T GTL +MAPEI+ +G S+ DIW+LG TVVEMLT +P + +L A+ N + P+ P L F FVKN RP A LL+
Sbjct: 18 ASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSAL----TLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEP-----LKDFLSKCFVKNMYKRPTADQLLK 268
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 140.584 bits (353), Expect = 8.914e-36 Identity = 86/262 (32.82%), Postives = 142/262 (54.20%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXX--XXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEII-EKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
MD+ + +++ E +G+G FG V+K + +V+A+KV+ LD + + I + + ++YGS L D S+ I E GSLR ++ + G + K RE L L +H+ NVIHRDIK N+L+T ++KL DFG++ V N++ + T GT Y+MAPE+I E Y + +DIW+LG+T E+ TG+P + + + + I+ P ++ + + L F L ++ R A DLL+ KF+
Sbjct: 17 MDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLL-RPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQV-NQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 134.42 bits (337), Expect = 8.808e-34 Identity = 87/261 (33.33%), Postives = 141/261 (54.02%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVE-NKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
D +Y L K+GQG+ G V+ E + A+K + L+ K LI +++ + + H +V F S ++ + + E++ GSL DV+ + LT Q RE+L GL+FLH V+HRDIK NILL+ IKLTDFG C + N+ + T GT Y+MAPE++ +K Y +DIW+LG+ ++EM+ G+P +++ P+ L+++A N P + N ++ L F R A +LL +++
Sbjct: 615 DPSTKYANLVKIGQGASGGVYTAYEIGTNVSVAIKQMNLEKQPKKELIINEILVMKGSKHPNIVNFIDSYVLKGDLWVIMEYMEGGSLTDVVT-HCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGF--CAQINELNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPYLNETPLRALYLIAT-NGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYI 871
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 130.568 bits (327), Expect = 2.472e-33 Identity = 85/254 (33.46%), Postives = 132/254 (51.97%), Query Frame = 1
Query: 97 VGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFY-GSKLVDFSICIFTEFVTKGSLRDVINKN--GNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEII--EKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
+G+G+FG V+K V++ ++++ A+KVV L+ + + I L+ Y + L D S+ I E+ GS D++ ++ L ++ + E GL +LHE IHRDIK NILL E +KL DFG+S + +S + TF GT Y+MAPE++ E GY+ DIW+LG+T E+L G P PM + + P ++ P ++ F VK A RP A +LL +F+ N
Sbjct: 24 IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHI--RSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGP-FSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKN 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]) HSP 1 Score: 122.479 bits (306), Expect = 1.577e-30 Identity = 84/266 (31.58%), Postives = 137/266 (51.50%), Query Frame = 1
Query: 97 VGQGSFGTVWKCVEKSSRKVFALKVV--ILDXXXXXXXXXXXXXXXXXXNHERLVKFYG--SKLVDFSICIFTEFVTKGSL----RDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTG------DPVFISLPPMLFILAILNFNPNDIKIP----NGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
+G+G+ G+V KC K+ +KVFALK + + + I L + + +V++YG + SI I E++ SL ++++ + G ++ + K L GL +LHE VIHRDIK NILL E IKL DFG+S N + TF GT ++MAPE I+ + YS + D+W+LG+T++E+ G D + ++ P+ + IL F+P P + + F K+A RP R +L+ +++
Sbjct: 220 LGEGAGGSVAKCRLKNGKKVFALKTINTMNTDPEYQKQIFRELQFNKSFKSDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVSGEAVNSLAM---TFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGRFPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPWIV 482
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 150.599 bits (379), Expect = 7.262e-42 Identity = 86/263 (32.70%), Postives = 143/263 (54.37%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXX-----XXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVEN-KSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTN-ELSYFFKLVFVKNAASRPKARDLLRCKFLLNT 846
+ K + +G G+FG V+ C + + + A+K + + + + +ER+V++YG + D I IF E++ GS+ + I ++G L T KY+R+ LEG+ +LH + ++HRDIK NIL + ++KL DFG SK ++ +S + GT Y+MAPE+I +GY D+W++G TVVEMLT P + PM + I P + ++P+ + + F + N+ SRP A +LLR F+ N+
Sbjct: 4 WRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIETGQLNSSTKNEVKALEGEIEFMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSKTGFRSVHGTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIAT-QPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADELLRFSFVTNS 265
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 150.214 bits (378), Expect = 3.451e-41 Identity = 88/259 (33.98%), Postives = 145/259 (55.98%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNE-LSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V +D + + + ++ + + + +VK+YGS + + I E+ GS+ D++ +N LT ++ + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY DIW+LG+T +EM G P + + PM I I P + P +E F VKN R A +LL+ F+ K
Sbjct: 24 FDVLEKLGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEIIKEISMMQQCDSPY--VVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFIQGAK 279
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 150.984 bits (380), Expect = 8.074e-41 Identity = 93/272 (34.19%), Postives = 152/272 (55.88%), Query Frame = 1
Query: 58 AMDIDAE--YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXX-NHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK**NAY 864
M D E + KLE++G+GSFG V+K ++ + +V A+K++ L+ A + + I + + K++GS L + I E++ GS D++ K GN+ A RE L+GLD+LH +HRDIK N+L++E +KL DFG++ + + ++ +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + F L K+ RP A++LL+ +F+ K NAY
Sbjct: 2 GMKADPEKLFSKLERIGKGSFGEVFKGIDNRTNEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSLYVTKYHGSYLKGTKLWIIMEYLGGGSALDLM-KAGNIEEFYIATILREVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVAGQLTD-TLNKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNNPPEL-TGNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRFIKTAK-KNAY 269
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO45846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL1]) HSP 1 Score: 140.969 bits (354), Expect = 4.166e-38 Identity = 82/251 (32.67%), Postives = 136/251 (54.18%), Query Frame = 1
Query: 94 KVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIP-NGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
K+G+GS G V +K + + A+K + L + L+ +++ H +V+ YGS LV + + EF+ G+L D++ + NL+ +Q A R L+ L FLH VIHRDIK +ILLT + +KL+DFG V + + + GT Y+MAPE+I +K Y + +DIW+LG+ V+EM+ G+P + + PP+ + + + P + P + L F +++ R A +LL F+ N
Sbjct: 34 KIGEGSTGIVCLATDKRTGRQVAVKKMDLKKQQRRELLFNEVVIMRDYPHPNIVEMYGSHLVGDELWVVMEFLEGGTLTDIVT-HTNLSEEQVACVCRAVLKALTFLHSQGVIHRDIKSDSILLTSNGTVKLSDFGFCAQV-TEDMPRRKSLVGTPYWMAPEVISRKPYGTEVDIWSLGIMVLEMVDGEPPYFNEPPLQAMRKLRDLEPPTSRNPIQISPRLQSFLDNALIRDPLYRATAFELLNHPFIRN 282
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHW1]) HSP 1 Score: 140.969 bits (354), Expect = 5.044e-38 Identity = 88/261 (33.72%), Postives = 147/261 (56.32%), Query Frame = 1
Query: 70 DAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEI--IEKK-GYSSSIDIWALGVTVVEMLTGDPVFISLPPM--LFILAILNFNPNDIKIPNG-TNELSYFFKLVFVKNAASRPKARDLLRCKF 834
D ++ +EKVG G++G V+K ++ + A+KVV ++ LI + + + + H ++ + G+ + + I E+ GS++DV G + Q + T E+L+GL +LHE +++HRDIK NILLT + +KL DFG+S + +++ +F GT Y+MAPE+ +E+ GY DIWA+G+T +EM P L PM L+I+ +F P +K + +NE+ +F K+ +KN RP A +L F
Sbjct: 15 DKVFDLIEKVGGGTYGDVFKARVIATGDLAAVKVVKVEPGDDFELIQQEIAMMQQCRHNNIINYIGAYMRRDKLWIGMEYCGGGSIQDVYCVTGPCSETQISFVTVETLKGLAYLHEKSLMHRDIKGANILLTTNGEVKLADFGISARI-TETMKKRKSFIGTPYWMAPEMAAVERTGGYDLKCDIWAVGITAIEMAELQPPMFDLHPMRALYIIGKKSFIPPTLKEKDKWSNEMHHFIKVALIKNPKKRPSADKMLTHPF 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000022068.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 158.303 bits (399), Expect = 5.758e-43 Identity = 89/260 (34.23%), Postives = 150/260 (57.69%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KL+++G+GSFG V+K ++ ++KV A+K++ L+ A + + I H + K++GS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ ++++
Sbjct: 17 DPEEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSSYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKALKEFIEACLNKDPSFRPTAKELLKHRYIV 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000022064.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 158.688 bits (400), Expect = 6.346e-43 Identity = 89/260 (34.23%), Postives = 150/260 (57.69%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KL+++G+GSFG V+K ++ ++KV A+K++ L+ A + + I H + K++GS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ ++++
Sbjct: 17 DPEEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSSYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKALKEFIEACLNKDPSFRPTAKELLKHRYIV 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000022066.2 (serine/threonine-protein kinase 24 [Source:NCBI gene;Acc:105356828]) HSP 1 Score: 158.688 bits (400), Expect = 6.346e-43 Identity = 89/260 (34.23%), Postives = 150/260 (57.69%), Query Frame = 1
Query: 64 DIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLL 840
D + + KL+++G+GSFG V+K ++ ++KV A+K++ L+ A + + I H + K++GS L + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + N TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ N + L F + K+ + RP A++LL+ ++++
Sbjct: 17 DPEEMFTKLDRIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCHSPFITKYFGSYLKSTKLWIIMEYLGGGSALDLL-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRN-TFVGTPFWMAPEVIKQSSYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE-GNYSKALKEFIEACLNKDPSFRPTAKELLKHRYIV 273
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: stk24b (serine/threonine kinase 24 [Source:NCBI gene;Acc:101160144]) HSP 1 Score: 157.532 bits (397), Expect = 2.042e-42 Identity = 93/264 (35.23%), Postives = 150/264 (56.82%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLV-KFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGT--NELSYFFKLVFVKNAASRPKARDLLRCKFLLN 843
+D + + KLE++G+GSFG V+K ++ ++KV A+K++ L+ A + + I V K+YGS L D + I E++ GS D++ + G L Q A RE L+GL++LH IHRDIK N+LL+E +KL DFG++ + + + I +TF GT ++MAPE+I++ Y S DIW+LG+T +E+ G+P L PM + I NP ++ G+ L F + K + RP A++LL+ K ++
Sbjct: 18 VDPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLM-EPGPLDETQIATILREILKGLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTD-TQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKNNPPTLE---GSYCKPLKEFVEACLNKEPSFRPTAKELLKHKLIVR 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: stk3 (serine/threonine-protein kinase 3 [Source:NCBI gene;Acc:101155570]) HSP 1 Score: 154.836 bits (390), Expect = 5.282e-41 Identity = 89/259 (34.36%), Postives = 148/259 (57.14%), Query Frame = 1
Query: 79 YEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVIN-KNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPN-GTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
++ LEK+G+GS+G+V+K + K S +V A+K V ++ + + + ++ + + + +VK+YGS + + I E+ GS+ D+I +N LT + A + +L+GL++LH IHRDIK GNILL H KL DFG++ + + ++ +T GT ++MAPE+I++ GY+ DIW+LG+T +EM G P + + PM I I P + P +++ + F K VKN R A LL+ F+ K
Sbjct: 27 FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPY--VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD-TMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFISQAK 282
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000071511.1 (SMESG000071511.1) HSP 1 Score: 493.812 bits (1270), Expect = 4.073e-175 Identity = 261/263 (99.24%), Postives = 261/263 (99.24%), Query Frame = 1
Query: 61 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 849
MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDIAILKSLISEILILREIANHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEK GYSSSIDIWALGVTVVEMLTG PVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK
Sbjct: 1 MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDIAILKSLISEILILREIANHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKTGYSSSIDIWALGVTVVEMLTGAPVFISLPPMLFILAILNFNPNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFLLNTK 263
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000024792.1 (SMESG000024792.1) HSP 1 Score: 177.178 bits (448), Expect = 1.679e-48 Identity = 103/291 (35.40%), Postives = 158/291 (54.30%), Query Frame = 1
Query: 76 EYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXN----------HERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVE--------------------------NKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIK-IPNGTNELSYFFKLVFVKNAASRPKARDLLRCKFL 837
+Y+K +G+G FG V+KC++ S + FA+K VIL S + + N H+R+V++YG+K +F++ IF E+++ GS++D + + G L + KYT++ L+GL FLH+ +IHRDIK NIL ++KL+DFG S+ ++ NKS + N +FCGT YFMAPE+I + YS+S DIW+LG TVVEMLTG+P + L P + I N + + K + + E+ F +F+ R A LL C F+
Sbjct: 302 DYKKGPLLGRGGFGQVYKCLDSESGREFAMKEVILASPYGYSSDAIKKDAECLENEILIYKELTCHQRIVQYYGAKRDNFAMYIFMEYMSGGSVKDQLRQYGTLPHRVVVKYTKQILQGLAFLHQKLIIHRDIKAANILRDVDGNVKLSDFGASRYLKSISIHNVSQNCSLMSSMNSAAGASKHNKSGLVN-SFCGTFYFMAPEVIRGESYSNSADIWSLGATVVEMLTGNPPYHDLEPYAALYRIANTSKVEYKPVEPISREMEAFIDQMFISIPQERATAESLLSCAFI 591
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000016973.1 (SMESG000016973.1) HSP 1 Score: 158.688 bits (400), Expect = 2.585e-42 Identity = 95/259 (36.68%), Postives = 148/259 (57.14%), Query Frame = 1
Query: 70 DAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSK--CVENKSVIDNHTFCGTLYFMAPEII---EKKGYSSSIDIWALGVTVVEMLTGDPVFISLPPMLFILAILNFNPNDIKIPNG---TNELSYFFKLVFVKNAASRPKARDLL 822
+ +EK K+G GSFG V+KC VFA+K +IL+ K + +I N+ER++++YG +CIF E++ + S+ + INKNG L + +Y+++ LEGL FLH +IHRDIK NILL + + +KLTDFG+S+ C E + + T CGT +FMAPE+I Y++S DIW++G TV+ M+TG P P ++ I N +++P+ + E+ F + + + RP A +LL
Sbjct: 266 EKNFEKGSKIGSGSFGEVFKCKGSGIPTVFAIKYLILEFIDSKYIEGDIHKFMPKLNNERIIQYYGVIQTKTHLCIFMEYLPQ-SIEEKINKNGPLETQDVVRYSKQILEGLQFLHNERIIHRDIKPANILLNQENCVKLTDFGVSRLLCGE---LSNPTTVCGTPHFMAPEVILADTNGPYNTSADIWSVGATVINMITGHPPNHKKRPEDVLIEIA--NDKKLQLPSSEMMSKEMKTFIEKMMNPDPNERPTATELL 518
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000016740.1 (SMESG000016740.1) HSP 1 Score: 155.606 bits (392), Expect = 3.959e-41 Identity = 93/252 (36.90%), Postives = 147/252 (58.33%), Query Frame = 1
Query: 82 EKLEKVGQGSFGTVWKCVEKSSRKVFALKVVI-LDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVF--ISLPP-MLFILAILNFN-PNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLL 822
+K E +GQG+FG V+KC+ + K +A+K++ D K I ++ NH R++K YGS + +CIF EF G+L + I+K L+ + +++++ LEG++ LH+ N+IHRDIK GNILL ++D++KL DF S+ KS+ TF GT F+APEI+ Y+ S DIW++G T M+TG+P + I +P +++ +A + F P D I + +L K + K+ RP A LL
Sbjct: 298 DKSEFLGQGAFGKVYKCISRKGDKKYAVKLIPKSDCGNTKEFKLLINEMKNQINHSRIIKVYGSFTKEKKLCIFMEFAAGGTLLNKISKESKLSRESVIRFSKQILEGVEHLHQMNIIHRDIKPGNILLDDNDNVKLADFDWSRTKGAKSLT---TFAGTPNFIAPEIVNDIHYTFSADIWSVGATTFNMITGEPPYNHIDIPETIMYKIATIGFEVPEDADI---SFDLREMIKAMMNKDQNKRPTATQLL 543
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000016740.1 (SMESG000016740.1) HSP 1 Score: 155.606 bits (392), Expect = 4.367e-41 Identity = 93/252 (36.90%), Postives = 147/252 (58.33%), Query Frame = 1
Query: 82 EKLEKVGQGSFGTVWKCVEKSSRKVFALKVVI-LDXXXXXXXXXXXXXXXXXXNHERLVKFYGSKLVDFSICIFTEFVTKGSLRDVINKNGNLTVKQTAKYTRESLEGLDFLHEHNVIHRDIKCGNILLTEHDHIKLTDFGLSKCVENKSVIDNHTFCGTLYFMAPEIIEKKGYSSSIDIWALGVTVVEMLTGDPVF--ISLPP-MLFILAILNFN-PNDIKIPNGTNELSYFFKLVFVKNAASRPKARDLL 822
+K E +GQG+FG V+KC+ + K +A+K++ D K I ++ NH R++K YGS + +CIF EF G+L + I+K L+ + +++++ LEG++ LH+ N+IHRDIK GNILL ++D++KL DF S+ KS+ TF GT F+APEI+ Y+ S DIW++G T M+TG+P + I +P +++ +A + F P D I + +L K + K+ RP A LL
Sbjct: 301 DKSEFLGQGAFGKVYKCISRKGDKKYAVKLIPKSDCGNTKEFKLLINEMKNQINHSRIIKVYGSFTKEKKLCIFMEFAAGGTLLNKISKESKLSRESVIRFSKQILEGVEHLHQMNIIHRDIKPGNILLDDNDNVKLADFDWSRTKGAKSLT---TFAGTPNFIAPEIVNDIHYTFSADIWSVGATTFNMITGEPPYNHIDIPETIMYKIATIGFEVPEDADI---SFDLREMIKAMMNKDQNKRPTATQLL 546 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30001161 ID=SMED30001161|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1546bpback to top protein sequence of SMED30001161-orf-1 >SMED30001161-orf-1 ID=SMED30001161-orf-1|Name=SMED30001161-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=264bp MDIDAEYEKLEKVGQGSFGTVWKCVEKSSRKVFALKVVILDIAILKSLISback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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