Ras-like GTP-binding protein YPT1

Overview


Name	Ras-like GTP-binding protein YPT1
Smed ID	SMED30001147
Length (bp)	750

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ras-like GTP-binding protein YPT1 (SMED30001147) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras-like GTP-binding protein YPT1 (SMED30001147) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras-like GTP-binding protein YPT1 (SMED30001147) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras-like GTP-binding protein YPT1 (SMED30001147) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001147

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30001147	SMESG000044147.1	dd_Smed_v4_6181_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30001147	SMESG000026323.1	dd_Smed_v4_488_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30001147	SMESG000026323.1	dd_Smed_v4_488_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30001147	SMESG000044147.1	dd_Smed_v6_6181_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30001147	SMESG000044147.1	dd_Smed_v4_6181_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Human
Match: RAB1A (RAB1A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9758])

HSP 1 Score: 222.246 bits (565), Expect = 8.340e-73
Identity = 108/170 (63.53%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV ++F+ +A  I
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172

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Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV ++F+ +A  I
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Human
Match: RAB4A (RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9781])

HSP 1 Score: 220.705 bits (561), Expect = 4.757e-72
Identity = 108/214 (50.47%), Postives = 146/214 (68.22%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG++G GKSCLL +F +  + +    TIGV+F  + I + GK +KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAPNAQECGC 218

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Human
Match: RAB4B (RAB4B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9782])

HSP 1 Score: 219.55 bits (558), Expect = 1.299e-71
Identity = 109/214 (50.93%), Postives = 144/214 (67.29%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M   YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC 213

[Close]

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M   YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRSAQAVAPQPCGC 213

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
Match: rab-1 (RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6])

HSP 1 Score: 219.935 bits (559), Expect = 2.640e-72
Identity = 108/177 (61.02%), Postives = 135/177 (76.27%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETV 586
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYD++D+E+FN + +WL ++ + + + +  +LVGNK D   + R V       +A +  + F+ETSA +  NV +AF+ +A  I   +  V
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDITDQETFNNVKQWLQEIDRYACENVNKLLVGNKCDLTAK-RAVETQAAQDYAGQLGIPFLETSAKSSTNVEQAFLTMASEIKSRMGPV 179

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 198.364 bits (503), Expect = 1.068e-63
Identity = 96/175 (54.86%), Postives = 127/175 (72.57%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            M   YDYLFKLLLIGDSGVGK+C+L RF+DD++  S+ISTIG+DFKIRTIELDGK IKLQIWDTAGQERFR++T +YYR A+G +LVYD+++  SF  +  W+ ++++ +   +  +++GNK D  +E REVS   G Q A E    F+ETSA    N+ EAF  +AR I   +E
Sbjct:    1 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCD-IEERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKME 174

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Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            M   YDYLFKLLLIGDSGVGK+C+L RF+DD++  S+ISTIG+DFKIRTIELDGK IKLQIWDTAGQERFR++T +YYR A+G +LVYD+++  SF  +  W+ ++++ +   +  +++GNK D  +E REVS   G Q A E    F+ETSA    N+ EAF  +AR I   +E
Sbjct:    1 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSDDSFNNSFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCD-IEERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKME 174

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3822883:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 193.356 bits (490), Expect = 1.166e-61
Identity = 93/171 (54.39%), Postives = 124/171 (72.51%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R + +DGK IKLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFI+ A+ I   ++
Sbjct:   12 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDL-EARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQ 181

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
Match: unc-108 (pep chromosome:WBcel235:I:3824947:3826514:1 gene:WBGene00006833.1 transcript:F53F10.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-108)

HSP 1 Score: 193.356 bits (490), Expect = 1.181e-61
Identity = 93/171 (54.39%), Postives = 124/171 (72.51%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R + +DGK IKLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFI+ A+ I   ++
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSNSNMVIMLIGNKSDL-EARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQ 172

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Match: Rab1 (gene:FBgn0285937 transcript:FBtr0084104)

HSP 1 Score: 220.32 bits (560), Expect = 2.312e-72
Identity = 114/208 (54.81%), Postives = 145/208 (69.71%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSA---DIRRPYLRTPTESC 670
            +NPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYD +D+ESFN + +WL ++++ + + +  +LVGNK D   + + V      ++A +  + F+ETSA +  NV +AF+ +A  I + +      P     D  S    D  RP   T +  C
Sbjct:    4 VNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTK-KVVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRV-----GPPSSATDNASKVKIDQGRPVENTKSGCC 205

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Match: Rab4 (gene:FBgn0016701 transcript:FBtr0086829)

HSP 1 Score: 211.46 bits (537), Expect = 1.016e-68
Identity = 100/176 (56.82%), Postives = 132/176 (75.00%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            M+  YDYLFK L+IG +G GKSCLL  F +  + +    TIGV+F  R + + GK++KLQIWDTAGQERFRSVT+SYYR A GALLVYD + R+SFN L+ WL D + L+   I+++LVGNK D  +E+R+V+F+E + FAQENEL+F+ETSA TGENV EAF+  ++ IL  +ET
Sbjct:    1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKD-LEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIET 175

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Match: Rab4 (gene:FBgn0016701 transcript:FBtr0086830)

HSP 1 Score: 211.46 bits (537), Expect = 1.016e-68
Identity = 100/176 (56.82%), Postives = 132/176 (75.00%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            M+  YDYLFK L+IG +G GKSCLL  F +  + +    TIGV+F  R + + GK++KLQIWDTAGQERFRSVT+SYYR A GALLVYD + R+SFN L+ WL D + L+   I+++LVGNK D  +E+R+V+F+E + FAQENEL+F+ETSA TGENV EAF+  ++ IL  +ET
Sbjct:    1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTNWLNDARTLASPNIVILLVGNKKD-LEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKCSKTILAKIET 175

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0343678)

HSP 1 Score: 202.216 bits (513), Expect = 4.245e-65
Identity = 92/171 (53.80%), Postives = 126/171 (73.68%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y+Y+FK ++IGD GVGKSCLL +F +  +  +   TIGV+F  R IE+D K IKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  + +REV++ E  +FA EN LMF+E SA+TG+NV EAF+  AR+I  N++
Sbjct:    8 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDL-ESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQ 177

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Match: Rab14 (gene:FBgn0015791 transcript:FBtr0080626)

HSP 1 Score: 202.216 bits (513), Expect = 4.245e-65
Identity = 92/171 (53.80%), Postives = 126/171 (73.68%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y+Y+FK ++IGD GVGKSCLL +F +  +  +   TIGV+F  R IE+D K IKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  + +REV++ E  +FA EN LMF+E SA+TG+NV EAF+  AR+I  N++
Sbjct:    8 YNYIFKYIIIGDMGVGKSCLLHQFTEKKFMANCPHTIGVEFGTRIIEVDDKKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIFLIGNKSDL-ESTREVTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQ 177

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
Match: rab1aa (RAB1A, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-090312-110])

HSP 1 Score: 225.328 bits (573), Expect = 2.853e-74
Identity = 109/170 (64.12%), Postives = 134/170 (78.82%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA +  NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTAAKEFADSLSIPFLETSAKSSTNVEQAFMTMAAEI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
Match: rab1ab (RAB1A, member RAS oncogene family b [Source:ZFIN;Acc:ZDB-GENE-030616-564])

HSP 1 Score: 223.402 bits (568), Expect = 1.745e-73
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
Match: rab1ba (zRAB1B, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-040426-873])

HSP 1 Score: 222.631 bits (566), Expect = 4.085e-73
Identity = 108/170 (63.53%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ES+N + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLAIPFLETSAKNATNVEQAFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 221.09 bits (562), Expect = 1.877e-72
Identity = 108/214 (50.47%), Postives = 145/214 (67.76%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     +R P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC 213

[Close]

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     +R P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSILNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC 213

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Match: rab1a (RAB1A, member RAS oncogene family [Source:NCBI gene;Acc:448007])

HSP 1 Score: 223.787 bits (569), Expect = 1.773e-73
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 172

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 218.009 bits (554), Expect = 5.017e-71
Identity = 102/176 (57.95%), Postives = 134/176 (76.14%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            M+  YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GK++KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   II+IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL  +E+
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDIASRETYNALTNWLTDARTLASPNIIIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIES 175

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Match: rab1a (RAB1A, member RAS oncogene family [Source:NCBI gene;Acc:448007])

HSP 1 Score: 213.386 bits (542), Expect = 2.658e-69
Identity = 105/168 (62.50%), Postives = 129/168 (76.79%), Query Frame = 2

Query:   62 PEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            P  DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    7 PTNDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 173

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Match: map4 (microtubule associated protein 4 [Source:Xenbase;Acc:XB-GENE-6259104])

HSP 1 Score: 204.527 bits (519), Expect = 9.271e-66
Identity = 96/166 (57.83%), Postives = 126/166 (75.90%), Query Frame = 2

Query:   86 LLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
             L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GK++KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   II+IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL  +E+
Sbjct:    5 FLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDIASRETYNALTNWLTDARTLASPNIIIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILSKIES 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Match: pknox2 (PBX/knotted 1 homeobox 2 [Source:Xenbase;Acc:XB-GENE-853128])

HSP 1 Score: 196.823 bits (499), Expect = 7.563e-63
Identity = 93/182 (51.10%), Postives = 134/182 (73.63%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPV 601
            M   YDYLFKLLLIGDSGVGK+CLL RF++D +  ++ISTIG+DFKIRTIELDGK IKLQIWDTAGQERFR++T +YYR A+G +LVYD+++ +SF+ +  W+ ++++ +   +  +++GNK D  D+ R+VS  +G + A +  + F+ETSA +  NV EAF  +AR I+  L   ++  +
Sbjct:    1 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDK-RQVSREKGEKLAIDYGIKFLETSAKSSINVEEAFFTLARDIMTKLNRKMNESI 181

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
Match: Rab1a (RAB1A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97842])

HSP 1 Score: 222.246 bits (565), Expect = 5.604e-73
Identity = 108/170 (63.53%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV ++F+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
Match: Rab1a (RAB1A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97842])

HSP 1 Score: 222.246 bits (565), Expect = 5.726e-73
Identity = 108/170 (63.53%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV ++F+ +A  I
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEI 172

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
Match: Rab4b (RAB4B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105071])

HSP 1 Score: 220.705 bits (561), Expect = 2.934e-72
Identity = 110/214 (51.40%), Postives = 145/214 (67.76%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M   YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I+VIL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +++    P    +  +  DI    LR P        + C C
Sbjct:    1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDL-DPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC 213

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
Match: Rab4a (RAB4A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:105069])

HSP 1 Score: 219.935 bits (559), Expect = 7.895e-72
Identity = 108/214 (50.47%), Postives = 146/214 (68.22%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG++G GKSCLL +F +  + +    TIGV+F  + I + GK +KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218

[Close]

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG++G GKSCLL +F +  + +    TIGV+F  + I + GK +KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRTQAPSAQECGC 218

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Match: sp|P33723|YPT1_NEUCR (GTP-binding protein ypt1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=ypt-1 PE=3 SV=1)

HSP 1 Score: 227.639 bits (579), Expect = 3.228e-74
Identity = 110/170 (64.71%), Postives = 135/170 (79.41%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKT+KLQIWDTAGQERFR++T SYYR A G  +VYDV+D +SFN + +WL ++ + + +G+  +LVGNK D  D+ + V +    +FA    + F+ETSA    NV +AF+ +AR+I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTVKLQIWDTAGQERFRTITSSYYRGAHGICVVYDVTDMDSFNNVKQWLQEIDRYATEGVNKLLVGNKSDMTDK-KVVEYTVAKEFADSLGIPFLETSAKNASNVEQAFLTMARQI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Match: sp|P40392|RIC1_ORYSJ (Ras-related protein RIC1 OS=Oryza sativa subsp. japonica OX=39947 GN=RIC1 PE=2 SV=2)

HSP 1 Score: 223.787 bits (569), Expect = 1.003e-72
Identity = 112/205 (54.63%), Postives = 145/205 (70.73%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESC 670
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADD+Y ESYISTIGVDFKIRT+E DGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   E+R VS+  G   A E  + F+ETSA    NV +AF+ +A  I + + +    P  + +   +  +R   +   +  C
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLESYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLNEIDRYASENVNKLLVGNKCDLA-ENRVVSYEAGKALADEIGIPFLETSAKDATNVEKAFMTMAGEIKNRMAS---QPATNASKPATVQMRGQPVAQQSSCC 201

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Match: sp|P22125|RAB1_DIPOM (Ras-related protein ORAB-1 OS=Diplobatis ommata OX=1870830 PE=2 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 1.437e-72
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Match: sp|Q01890|YPT1_PHYIN (Ras-like GTP-binding protein YPT1 OS=Phytophthora infestans OX=4787 GN=YPT1 PE=3 SV=1)

HSP 1 Score: 223.016 bits (567), Expect = 1.656e-72
Identity = 112/181 (61.88%), Postives = 137/181 (75.69%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHP 598
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + R VS     +FA+   + F+ETSA    NV +AF+ +A +I   +      P
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLHEIDRYACENVNKLLVGNKSDLTAK-RVVSTDAAKEFAESLGIEFLETSAKNAANVEKAFMMMAAQIKKRMANAPVAP 180

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Match: sp|Q05974|RAB1A_LYMST (Ras-related protein Rab-1A OS=Lymnaea stagnalis OX=6523 GN=RAB1A PE=2 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 1.768e-72
Identity = 108/174 (62.07%), Postives = 136/174 (78.16%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 577
            MNP+YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V F    ++A +  + F+ETSA    NV +AF+ +A  I + +
Sbjct:    4 MNPDYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKSDLTTK-KVVDFTTAKEYADQLGIPFLETSAKNATNVEQAFMTMAAEIKNRM 176

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BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Match: A0A1R1YK96 (GTP-binding protein ypt1 OS=Smittium culicis OX=133412 GN=AYI69_g3254 PE=4 SV=1)

HSP 1 Score: 235.343 bits (599), Expect = 8.218e-75
Identity = 112/170 (65.88%), Postives = 141/170 (82.94%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL+GKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + +G+  +LVGNK D  +ESR V F +  +FA++  + F+ETSA    NV +AF+ +A++I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELEGKTVKLQIWDTAGQERFRTITSSYYRGAYGIIVVYDVTDQESFNNVERWLQEIGRYASEGVNKLLVGNKSDL-EESRAVDFTQAKEFAEQLGIPFLETSAKDSTNVEQAFLTMAKQI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Match: A0A1A8N8D2 (Uncharacterized protein (Fragment) OS=Nothobranchius pienaari OX=704102 GN=Nfu_g_1_017174 PE=4 SV=1)

HSP 1 Score: 232.646 bits (592), Expect = 1.436e-73
Identity = 107/175 (61.14%), Postives = 141/175 (80.57%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            M  +YDYLFKLL+IGDSGVGKS LLLRFAD+T++ SYI+TIGVDFKIRT+EL+G+ +KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++IL+GNK D  +  R+V++ E  QFA+EN L+F+E SA TGENV EAF+  A++I  N++
Sbjct:    4 MARDYDYLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVELNGEKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGENVEEAFLEAAKKIYQNIQ 177

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BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Match: A0A2T9YJ14 (Uncharacterized protein OS=Smittium simulii OX=133385 GN=BB561_003900 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 2.687e-73
Identity = 110/170 (64.71%), Postives = 138/170 (81.18%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEL+GKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+D ESFN + +WL ++ + + +G+  +LVGNK D   ESR V + +  +FA +  + ++ETSA    NV +AF+ +A++I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELEGKTVKLQIWDTAGQERFRTITSSYYRGAYGIIVVYDVTDLESFNNVERWLQEIGRYASEGVNKLLVGNKCDLS-ESRAVDYTQAKEFADQIGIPYLETSAKDSTNVEQAFLTMAKQI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Match: A0A139XVT8 (Putative small GTP binding protein rab1a OS=Toxoplasma gondii ARI OX=1074872 GN=TGARI_214770 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 3.431e-73
Identity = 111/170 (65.29%), Postives = 135/170 (79.41%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            M PEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI+LDGKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+DRESFN +  W++++ + + +G+  +LVGNK D   + R V++ EG +FA    + FIETSA    NV +AF  +A  I
Sbjct:    1 MKPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIDLDGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTDRESFNNVKNWMMEIDKYAMEGVSKLLVGNKCDLTSK-RTVTYEEGKEFADSCNMRFIETSAKNAHNVEQAFHIMASEI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Match: A0A125YLS2 (Small GTP binding protein rab1a, putative OS=Toxoplasma gondii (strain ATCC 50611 / Me49) OX=508771 GN=TGME49_214770 PE=4 SV=1)

HSP 1 Score: 231.106 bits (588), Expect = 3.431e-73
Identity = 111/170 (65.29%), Postives = 135/170 (79.41%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            M PEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI+LDGKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+DRESFN +  W++++ + + +G+  +LVGNK D   + R V++ EG +FA    + FIETSA    NV +AF  +A  I
Sbjct:    1 MKPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIDLDGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTDRESFNNVKNWMMEIDKYAMEGVSKLLVGNKCDLTSK-RTVTYEEGKEFADSCNMRFIETSAKNAHNVEQAFHIMASEI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Match: rab1ab (ras-related protein Rab-1A [Source:NCBI gene;Acc:103035225])

HSP 1 Score: 223.402 bits (568), Expect = 1.297e-73
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 169

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Match: zgc:171927 (ras-related protein ORAB-1-like [Source:NCBI gene;Acc:103045400])

HSP 1 Score: 223.402 bits (568), Expect = 1.798e-73
Identity = 108/174 (62.07%), Postives = 135/174 (77.59%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 577
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIE+DGK +KLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN L +WL ++ + + + +  +LVGNK D   + + V F    +FA+  ++ F+E+SA    NV +AF+ +A  I   L
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIEMDGKIVKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTDQESFNNLKQWLEEIDRYACENVSKLLVGNKSDLTSK-KVVDFTTAKEFAEPLKIPFLESSAKNASNVEKAFLTMASEIQKRL 173

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Match: ENSAMXT00000045110.1 (ras-related protein Rab-1A [Source:NCBI gene;Acc:103028654])

HSP 1 Score: 222.631 bits (566), Expect = 3.577e-73
Identity = 112/205 (54.63%), Postives = 145/205 (70.73%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESC 670
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  ++VGNK D   + + V +    +FA    + F+E SA    NV +AF+ +A  I   + +       D ++ +   I+   ++T T  C
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASESVNKLMVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLEASAKNATNVEQAFMTMAAEIKKRMGSGTSGGGADKSNVK---IQSTPVKTSTGGC 201

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:103022831])

HSP 1 Score: 222.246 bits (565), Expect = 5.464e-73
Identity = 109/214 (50.93%), Postives = 145/214 (67.76%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R + + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+    P    +  +  D     LR P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIESGELDPERMGSGIQYGDASLRQLRQPRGTAAQTKQQCNC 213

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Match: rab4a (RAB4A, member RAS oncogene family [Source:NCBI gene;Acc:103032660])

HSP 1 Score: 216.468 bits (550), Expect = 1.000e-70
Identity = 107/214 (50.00%), Postives = 145/214 (67.76%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG++G GKSCLL +F +  + +    TIGV+F  + I +  K +KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P        + C C
Sbjct:    1 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVVNKFVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQAESVQECGC 213

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Match: rab1aa (RAB1A, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-090312-110])

HSP 1 Score: 226.483 bits (576), Expect = 2.362e-75
Identity = 110/170 (64.71%), Postives = 134/170 (78.82%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA   E+ F+ETSA    NV +AF+ +A  I
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLEIPFLETSAKNATNVEQAFMTMAAEI 172

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Match: rab4b (RAB4B, member RAS oncogene family [Source:NCBI gene;Acc:445498])

HSP 1 Score: 207.994 bits (528), Expect = 7.052e-68
Identity = 100/174 (57.47%), Postives = 131/174 (75.29%), Query Frame = 2

Query:   71 DYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVS--DRESFNGLSKWLIDVKQLSGDGIIVILVGNKID-RPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            D+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  + +   GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++   RE++N L+ WL D + L+   I +IL GNK D  PD  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR IL+ +E+
Sbjct:   10 DFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSKVVNTGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSGSRETYNALTNWLADARTLASPNIAIILCGNKKDLEPD--REVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIES 181

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002219.1 (pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene:ENSPMAG00000002006.1 transcript:ENSPMAT00000002219.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 197.208 bits (500), Expect = 7.852e-64
Identity = 97/213 (45.54%), Postives = 136/213 (63.85%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP----------TESCRC 676
            Y Y+FK ++IGD GVGKSCLL +F +  +      TIGV+F  R IE+ G+ +KLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  +  R+V++ E  QFA+EN L+F+E SA TG+NV EAF+  A++I  N++   D  + D+N   S    +P    P           +SC C
Sbjct:    8 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKADL-EAQRDVTYEEAKQFAEENGLLFLEASAKTGDNVEEAFLETAKKIYQNIQ---DGSL-DLNAAESGVQHKPATPQPGRLASDAQPAKDSCSC 215

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Match: rab2a (RAB2A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-011212-2])

HSP 1 Score: 195.282 bits (495), Expect = 4.345e-63
Identity = 94/171 (54.97%), Postives = 124/171 (72.51%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R I +DGK +KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   ++++L+GNK D  +  REV   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   ++
Sbjct:    3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSD-LESRREVKREEGEAFAREHGLVFMETSAKTASNVEEAFINTAKEIYEKIQ 172

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Match: RAB2B (RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246])

HSP 1 Score: 193.741 bits (491), Expect = 7.118e-63
Identity = 97/176 (55.11%), Postives = 126/176 (71.59%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL-ETVLD 592
            Y YLFK ++IGD+GVGKSCLLL+F D  +   +  TIGV+F  R I +DGK +KLQIWDTAGQE FRS+T+SYYR A GALLVYD++ R++FN L+ WL D +Q S   +I++L+GNK D  +  R+V   EG  FA+E+ L+F+ETSA T  NV EAFIN A+ I   + E V D
Sbjct:    8 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMINIDGKQVKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSSSNMIIMLIGNKSD-LESRRDVKREEGEAFAREHGLVFMETSAKTAANVEEAFINTAKEIYQRIHEGVFD 182

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 222.246 bits (565), Expect = 5.895e-74
Identity = 105/174 (60.34%), Postives = 138/174 (79.31%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 577
            MN EYDYLFKLLLIG+SGVGKSCLLLRF+DDTYT  YISTIGVDFKI+T+ELDGKT+KLQIWDTAGQERFR++T SYYR + G ++VYDV+D+ESFNG+  WL ++ + +   ++ +LVGNK D  D+ R V +    +FA  N++ F+ETSA+   NV +AF+ +AR+I  ++
Sbjct:    1 MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDK-RVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESM 173

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 177.178 bits (448), Expect = 3.914e-56
Identity = 84/172 (48.84%), Postives = 125/172 (72.67%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            YD + K+LLIGDSGVGKSCLL+RF +D +  S+I+TIG+DFKI+T++++GK +KLQ+WDTAGQERFR++T +YYR A+G +LVYDV+D  +F  + +W   V + + D   ++LVGNK D   E+R V+  +G   A+E  + FIE+SA   +NV+E F  +A+ I   +++
Sbjct:   17 YDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDM--ETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDS 186

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 174.481 bits (441), Expect = 5.355e-55
Identity = 86/160 (53.75%), Postives = 113/160 (70.62%), Query Frame = 2

Query:   65 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAF 544
            +YD LFK++LIGDSGVGKS LL RF  + +     STIGV+F  RT+E+DGK IK QIWDTAGQER+R++T +YYR AVGAL+VYD+S   S+   + WL ++++ + D + V L+GNK D     R V   E   FAQEN+L+F ETSA+  ENV +AF
Sbjct:    9 DYDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLA-HLRAVPTEESKTFAQENQLLFTETSALNSENVDKAF 167

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Match: YPT32 (Rab family GTPase involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; protein abundance increases in response to DNA replication stress; YPT32 has a paralog, YPT31, that arose from the whole genome duplication [Source:SGD;Acc:S000003178])

HSP 1 Score: 172.17 bits (435), Expect = 5.281e-54
Identity = 89/180 (49.44%), Postives = 120/180 (66.67%), Query Frame = 2

Query:   65 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVD 604
            +YDYLFK++LIGDSGVGKS LL RF  D +     STIGV+F  RTIE++ K IK QIWDTAGQER+R++T +YYR AVGAL+VYD+S   S+   + WL ++++ + D + V L+GNK D     R V   E   FA EN+++F ETSA+  +NV +AF  +   I+   + V  H VD
Sbjct:    9 DYDYLFKIVLIGDSGVGKSNLLSRFTTDEFNIESKSTIGVEFATRTIEVENKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLTELRENADDNVAVGLIGNKSDLA-HLRAVPTDEAKNFAMENQMLFTETSALNSDNVDKAFREL---IVAIFQMVSKHQVD 184

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Match: YPT6 (Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6 [Source:SGD;Acc:S000004252])

HSP 1 Score: 145.206 bits (365), Expect = 1.382e-43
Identity = 86/208 (41.35%), Postives = 128/208 (61.54%), Query Frame = 2

Query:   80 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGD-GIIVILVGNKIDRPDESREVSFVEGTQFAQ-ENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPY---LRTPTE----SCRC 676
            +K++ +G+ GVGK+ L+ RF  DT+ + Y +TIG+DF  +T+ LD KTI+LQ+WDTAGQERFRS+  SY R +  A++VYD++ R+SF  + KW+ DVK   GD  +I+ +VGNK D  DE R++S  EG + A+     +F+ETS   G NV   F  +A+  L   +     P+D  N   SA+  +P    + T  E    +C+C
Sbjct:   11 YKIVFLGEQGVGKTSLITRFMYDTFDDHYQATIGIDFLSKTMYLDDKTIRLQLWDTAGQERFRSLIPSYIRDSRVAIIVYDITKRKSFEYIDKWIEDVKNERGDENVILCIVGNKSDLSDE-RQISTEEGEKKAKLLGAKIFMETSTKAGYNVKALFKKIAKS-LPEFQNSESTPLDSEN-ANSANQNKPGVIDISTAEEQEQSACQC 215

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BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Match: EDO40167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S806])

HSP 1 Score: 224.557 bits (571), Expect = 2.183e-74
Identity = 109/174 (62.64%), Postives = 136/174 (78.16%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 577
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V F    ++A+   + F+ETSA    NV +AF+ +A  I + +
Sbjct:    4 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYACENVNKLLVGNKCDLTTK-KVVDFTTAKEYAESLGVPFLETSAKNATNVEQAFMTMAAEIKNRM 176

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Match: EDO43047 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZT6])

HSP 1 Score: 214.927 bits (546), Expect = 2.106e-70
Identity = 100/176 (56.82%), Postives = 134/176 (76.14%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            M+  YD+LFK L+IG +G GKSC+L +F +  + +    TIGV+F  + + + GK++KLQIWDTAGQERFRSVT+SYYR A GALLVYD+S RE+FN L+ WL D + L+   I++ILVGNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  +R IL+ +E+
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCILHQFIEGKFKQDSSHTIGVEFGSKIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDISSRETFNSLTNWLTDARTLASPNIVIILVGNKKDL-DADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCSRTILNKIES 175

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Match: EDO43129 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZN1])

HSP 1 Score: 209.149 bits (531), Expect = 2.197e-68
Identity = 98/165 (59.39%), Postives = 131/165 (79.39%), Query Frame = 2

Query:   65 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVAR 559
            +YDYLFK+LLIGDSGVGKSCLLLRF DD++ ESY +TIGVDFKI+T+ +DGK +KLQIWDTAGQERFR++T SYYR A G ++VYD++ RES+N L KWL++V+  + +G+ +ILVGNKID  D  REV      ++A  +++ F+ETSA   +NV EAF+ ++R
Sbjct:   12 QYDYLFKILLIGDSGVGKSCLLLRFVDDSHRESYQTTIGVDFKIKTMRVDGKVVKLQIWDTAGQERFRTITSSYYRGAHGVMIVYDITKRESYNNLHKWLMEVETYASEGVHMILVGNKIDL-DTDREVQPDAAQEWAALHDMPFVETSAKGAKNVKEAFLVLSR 175

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Match: EDO42144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2G3])

HSP 1 Score: 209.149 bits (531), Expect = 3.139e-68
Identity = 105/182 (57.69%), Postives = 134/182 (73.63%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPV 601
            MN EYDYLFKLLLIGDSGVGKS LLLRFADDT++ +YISTIGVDFKIRT+ +DGKTIKLQIWDTAGQERFR++T +YYR A G +L+YDV++ E+F  LS+WL +V + + +G+  ILVGNK D  D  R+V +    +FA++ ++ FIETSA    NV   F  +A  +   L + L  P 
Sbjct:    1 MNSEYDYLFKLLLIGDSGVGKSSLLLRFADDTFSNTYISTIGVDFKIRTLTVDGKTIKLQIWDTAGQERFRTLTTAYYRSAHGIVLIYDVNESETFLHLSQWLEEVSEYACEGVNTILVGNKCDLID-CRQVGYNTAKEFAEKLDISFIETSAKDSTNVESVFRTMAAELKAKLGSPLTSPT 181

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Match: EDO43319 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ04])

HSP 1 Score: 196.823 bits (499), Expect = 2.275e-63
Identity = 90/171 (52.63%), Postives = 122/171 (71.35%), Query Frame = 2

Query:   68 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLE 580
            Y Y+FK ++IGD GVGKSCLL +F +  +      TIGV+F  R IE+ G+ IKLQIWDTAGQERFR+VT+SYYR A GAL+VYD++ R ++N LS WL D + L+    ++ L+GNK D  D  R+V++ E  QFA+EN L+F E SA TGENV +AF+  A++I  N++
Sbjct:    9 YSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKSDL-DAQRDVTYEEAKQFAEENGLLFCEASAKTGENVEDAFLETAKKIYQNIQ 178

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Match: rab1aa (ras-related protein Rab-1A [Source:NCBI gene;Acc:101162421])

HSP 1 Score: 223.787 bits (569), Expect = 1.234e-73
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D     + V +    +FA    + F+ETSA +  NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTR-KVVDYTTAKEFADNLGIPFLETSAKSATNVEQAFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Match: rab1ab (ras-related protein ORAB-1 [Source:NCBI gene;Acc:101161080])

HSP 1 Score: 223.016 bits (567), Expect = 1.848e-73
Identity = 109/170 (64.12%), Postives = 133/170 (78.24%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ESFN + +WL ++ + + + +  +LVGNK D   + + V +    +FA    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTK-KVVDYTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Match: rab4b (ras-related protein Rab-4B [Source:NCBI gene;Acc:101159839])

HSP 1 Score: 220.32 bits (560), Expect = 3.281e-72
Identity = 109/214 (50.93%), Postives = 144/214 (67.29%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG +G GKSCLL +F ++ + +    TIGV+F  R I + GKT+KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N LS WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV E F+  AR IL+ +++    P    +  +  D     LR P        + C C
Sbjct:    1 MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVINVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALSNWLTDARTLASPNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEGFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQLRQPRGTTTQNKQQCNC 213

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Match: rab4a (RAB4A, member RAS oncogene family [Source:NCBI gene;Acc:101158840])

HSP 1 Score: 218.009 bits (554), Expect = 2.718e-71
Identity = 108/214 (50.47%), Postives = 146/214 (68.22%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTP-------TESCRC 676
            M+  YD+LFK L+IG++G GKSCLL +F +  + +    TIGV+F  + I +  K +KLQIWDTAGQERFRSVT+SYYR A GALLVYD++ RE++N L+ WL D + L+   I++IL GNK D  D  REV+F+E ++FAQENELMF+ETSA+TGENV EAF+  AR+IL+ +E+    P    +  +  D     LR+P       T+ C C
Sbjct:    1 MSESYDFLFKFLVIGNAGTGKSCLLHQFIEKRFKDESNHTIGVEFGSKIISVVNKMVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTTWLSDARMLASQNIVIILCGNKKD-LDADREVTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRAQPQGTQECGC 213

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Match: zgc:171927 (ras-related protein ORAB-1-like [Source:NCBI gene;Acc:101173484])

HSP 1 Score: 213.386 bits (542), Expect = 1.600e-69
Identity = 105/176 (59.66%), Postives = 134/176 (76.14%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET 583
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI++DGKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+++ESFN + +WL ++ + + + +  +LVGNK D   + + V        A   ++ F+ETSA +  NV +AF+ +A  I   L +
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIDMDGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDVTEQESFNNVRQWLEEIDRYACENVSRLLVGNKSDLVSK-KVVDAATAQDLASSLKIPFLETSAKSSGNVEKAFLTMASEIHSRLAS 175

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Match: SMESG000044147.1 (SMESG000044147.1)

HSP 1 Score: 362.459 bits (929), Expect = 1.495e-128
Identity = 175/207 (84.54%), Postives = 188/207 (90.82%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 676
            M+  YD+LFK LLIG+SGVGKSC+L +F ++ +      TIGV+F  + I +  + +KLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC
Sbjct:    1 MSEIYDHLFKFLLIGNSGVGKSCVLNQFIEEQFRMDSTHTIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 207

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Match: SMESG000044147.1 (SMESG000044147.1)

HSP 1 Score: 324.324 bits (830), Expect = 6.501e-114
Identity = 156/168 (92.86%), Postives = 161/168 (95.83%), Query Frame = 2

Query:  173 TIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 676
            TIGV+F  + I +  + +KLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC
Sbjct:    6 TIGVEFASKIISIASRKVKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRTPTESCRC 173

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Match: SMESG000026323.1 (SMESG000026323.1)

HSP 1 Score: 218.779 bits (556), Expect = 6.771e-72
Identity = 108/170 (63.53%), Postives = 131/170 (77.06%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRI 565
            MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFR++T SYYR A G ++VYDV+D++SFN +  WL ++ + + + +  +LVGNK D   + R V      ++A    + F+ETSA    NV +AF+ +A  I
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQDSFNNVKNWLSEIDRYANENVNKLLVGNKTDLISK-RVVEASNAKEYADSLNIPFLETSAKDATNVEQAFLTMAGEI 169

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Match: SMESG000049854.1 (SMESG000049854.1)

HSP 1 Score: 214.157 bits (544), Expect = 4.805e-70
Identity = 105/174 (60.34%), Postives = 133/174 (76.44%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNL 577
            MNPEYDYLFKLLLIGDSGVGKSC+LLRFADDTYT+SYISTIGVDFKIRTIELDGKT+KLQIWDTAGQERFR++T SYYR A G ++VYDV+D+ SFN +  WL ++++ + + +  +L+GNK D   + + V      +FA    + F+ETSA    NV + FI +A+ I + L
Sbjct:    1 MNPEYDYLFKLLLIGDSGVGKSCILLRFADDTYTDSYISTIGVDFKIRTIELDGKTVKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQTSFNNVKNWLNEIERYANENVNKLLIGNKSDMVSK-KVVDSGTAKEFADSLNIPFLETSARDSTNVEKTFITMAQEIKNRL 173

[Close]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Match: SMESG000044157.1 (SMESG000044157.1)

HSP 1 Score: 209.92 bits (533), Expect = 4.902e-68
Identity = 102/203 (50.25%), Postives = 143/203 (70.44%), Query Frame = 2

Query:   56 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLSKWLIDVKQLSGDGIIVILVGNKIDRPD--ESREVSFVEGTQFAQENELMFIETSAVTGENVSEAFINVARRILHNLET--VLDHPVDDVNDFRSADIRRPYLR 652
            MN +Y++LFK L+IG++GVGKSC+L  F +    E+ + TIGV+F  + I+++ +TIKLQIWDTAGQERFRSV +SYYR A GAL+VYDV++R+SFN +  WL D K L+G  +  ILVGNK D  D   SREVS+ E   FA+ENE+ F ETSAV+GE++ + FI+ AR ++   E+  + D+   + +   S DIR+ + R
Sbjct:    1 MNEQYEFLFKFLIIGNAGVGKSCILHHFIEQKVKENSVHTIGVEFASKIIQVNNRTIKLQIWDTAGQERFRSVARSYYRGASGALVVYDVTNRDSFNAIINWLSDAKSLAGTNLSAILVGNKKDLADYKASREVSYAEAEAFARENEMQFYETSAVSGEHIDDVFIDCARAVVCKWESNDLSDNIAQNSSSQNSGDIRKRWNR 203

The following BLAST results are available for this feature:

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Human
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
RAB1A	8.340e-73	63.53	RAB1A, member RAS oncogene family [Source:HGNC Sym...	[more]
RAB1A	8.340e-73	63.53	RAB1A, member RAS oncogene family [Source:HGNC Sym...	[more]
RAB4A	4.757e-72	50.47	RAB4A, member RAS oncogene family [Source:HGNC Sym...	[more]
RAB4B	1.299e-71	50.93	RAB4B, member RAS oncogene family [Source:HGNC Sym...	[more]
RAB4B	1.299e-71	50.93	RAB4B, member RAS oncogene family [Source:HGNC Sym...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab-1	2.640e-72	61.02	RAB family [Source:UniProtKB/TrEMBL;Acc:Q9UAQ6]	[more]
rab-8	1.068e-63	54.86	RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E...	[more]
rab-8	1.068e-63	54.86	RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E...	[more]
unc-108	1.166e-61	54.39	pep chromosome:WBcel235:I:3822883:3826514:1 gene:W...	[more]
unc-108	1.181e-61	54.39	pep chromosome:WBcel235:I:3824947:3826514:1 gene:W...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rab1	2.312e-72	54.81	gene:FBgn0285937 transcript:FBtr0084104	[more]
Rab4	1.016e-68	56.82	gene:FBgn0016701 transcript:FBtr0086829	[more]
Rab4	1.016e-68	56.82	gene:FBgn0016701 transcript:FBtr0086830	[more]
Rab14	4.245e-65	53.80	gene:FBgn0015791 transcript:FBtr0343678	[more]
Rab14	4.245e-65	53.80	gene:FBgn0015791 transcript:FBtr0080626	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab1aa	2.853e-74	64.12	RAB1A, member RAS oncogene family a [Source:ZFIN;A...	[more]
rab1ab	1.745e-73	64.12	RAB1A, member RAS oncogene family b [Source:ZFIN;A...	[more]
rab1ba	4.085e-73	63.53	zRAB1B, member RAS oncogene family a [Source:ZFIN;...	[more]
rab4b	1.877e-72	50.47	RAB4B, member RAS oncogene family [Source:NCBI gen...	[more]
rab4b	1.877e-72	50.47	RAB4B, member RAS oncogene family [Source:NCBI gen...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab1a	1.773e-73	64.12	RAB1A, member RAS oncogene family [Source:NCBI gen...	[more]
map4	5.017e-71	57.95	microtubule associated protein 4 [Source:Xenbase;A...	[more]
rab1a	2.658e-69	62.50	RAB1A, member RAS oncogene family [Source:NCBI gen...	[more]
map4	9.271e-66	57.83	microtubule associated protein 4 [Source:Xenbase;A...	[more]
pknox2	7.563e-63	51.10	PBX/knotted 1 homeobox 2 [Source:Xenbase;Acc:XB-GE...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rab1a	5.604e-73	63.53	RAB1A, member RAS oncogene family [Source:MGI Symb...	[more]
Rab1a	5.726e-73	63.53	RAB1A, member RAS oncogene family [Source:MGI Symb...	[more]
Rab4b	2.934e-72	51.40	RAB4B, member RAS oncogene family [Source:MGI Symb...	[more]
Rab4a	7.895e-72	50.47	RAB4A, member RAS oncogene family [Source:MGI Symb...	[more]
Rab4a	7.895e-72	50.47	RAB4A, member RAS oncogene family [Source:MGI Symb...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P33723\|YPT1_NEUCR	3.228e-74	64.71	GTP-binding protein ypt1 OS=Neurospora crassa (str...	[more]
sp\|P40392\|RIC1_ORYSJ	1.003e-72	54.63	Ras-related protein RIC1 OS=Oryza sativa subsp. ja...	[more]
sp\|P22125\|RAB1_DIPOM	1.437e-72	64.12	Ras-related protein ORAB-1 OS=Diplobatis ommata OX...	[more]
sp\|Q01890\|YPT1_PHYIN	1.656e-72	61.88	Ras-like GTP-binding protein YPT1 OS=Phytophthora ...	[more]
sp\|Q05974\|RAB1A_LYMST	1.768e-72	62.07	Ras-related protein Rab-1A OS=Lymnaea stagnalis OX...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1R1YK96	8.218e-75	65.88	GTP-binding protein ypt1 OS=Smittium culicis OX=13...	[more]
A0A1A8N8D2	1.436e-73	61.14	Uncharacterized protein (Fragment) OS=Nothobranchi...	[more]
A0A2T9YJ14	2.687e-73	64.71	Uncharacterized protein OS=Smittium simulii OX=133...	[more]
A0A139XVT8	3.431e-73	65.29	Putative small GTP binding protein rab1a OS=Toxopl...	[more]
A0A125YLS2	3.431e-73	65.29	Small GTP binding protein rab1a, putative OS=Toxop...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab1ab	1.297e-73	64.12	ras-related protein Rab-1A [Source:NCBI gene;Acc:1...	[more]
zgc:171927	1.798e-73	62.07	ras-related protein ORAB-1-like [Source:NCBI gene;...	[more]
ENSAMXT00000045110.1	3.577e-73	54.63	ras-related protein Rab-1A [Source:NCBI gene;Acc:1...	[more]
rab4b	5.464e-73	50.93	ras-related protein Rab-4B [Source:NCBI gene;Acc:1...	[more]
rab4a	1.000e-70	50.00	RAB4A, member RAS oncogene family [Source:NCBI gen...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab1aa	2.362e-75	64.71	RAB1A, member RAS oncogene family a [Source:ZFIN;A...	[more]
rab4b	7.052e-68	57.47	RAB4B, member RAS oncogene family [Source:NCBI gen...	[more]
ENSPMAT00000002219.1	7.852e-64	45.54	pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene...	[more]
rab2a	4.345e-63	54.97	RAB2A, member RAS oncogene family [Source:ZFIN;Acc...	[more]
RAB2B	7.118e-63	55.11	RAB2B, member RAS oncogene family [Source:HGNC Sym...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
YPT1	5.895e-74	60.34	Rab family GTPase; involved in the ER-to-Golgi ste...	[more]
SEC4	3.914e-56	48.84	Rab family GTPase; essential for vesicle-mediated ...	[more]
YPT31	5.355e-55	53.75	Rab family GTPase; involved in the exocytic pathwa...	[more]
YPT32	5.281e-54	49.44	Rab family GTPase involved in the exocytic pathway...	[more]
YPT6	1.382e-43	41.35	Rab family GTPase; required for endosome-to-Golgii...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40167	2.183e-74	62.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43047	2.106e-70	56.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43129	2.197e-68	59.39	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42144	3.139e-68	57.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43319	2.275e-63	52.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rab1aa	1.234e-73	64.12	ras-related protein Rab-1A [Source:NCBI gene;Acc:1...	[more]
rab1ab	1.848e-73	64.12	ras-related protein ORAB-1 [Source:NCBI gene;Acc:1...	[more]
rab4b	3.281e-72	50.93	ras-related protein Rab-4B [Source:NCBI gene;Acc:1...	[more]
rab4a	2.718e-71	50.47	RAB4A, member RAS oncogene family [Source:NCBI gen...	[more]
zgc:171927	1.600e-69	59.66	ras-related protein ORAB-1-like [Source:NCBI gene;...	[more]

BLAST of Ras-like GTP-binding protein YPT1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000044147.1	1.495e-128	84.54	SMESG000044147.1	[more]
SMESG000044147.1	6.501e-114	92.86	SMESG000044147.1	[more]
SMESG000026323.1	6.771e-72	63.53	SMESG000026323.1	[more]
SMESG000049854.1	4.805e-70	60.34	SMESG000049854.1	[more]
SMESG000044157.1	4.902e-68	50.25	SMESG000044157.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001147 ID=SMED30001147|Name=Ras-like GTP-binding protein YPT1|organism=Schmidtea mediterranea sexual|type=transcript|length=750bp
GCACCTCTATAATTGTTTATCTGTTTATCGAAACCGGAACGTTGACAATA
ATTAAATGAATCCAGAATATGACTATTTATTCAAACTTCTTCTAATTGGA
GATTCTGGTGTTGGAAAATCTTGTTTATTACTCAGATTTGCAGATGATAC
TTATACTGAAAGTTACATAAGCACAATTGGAGTTGACTTTAAAATCAGAA
CTATTGAATTAGATGGTAAAACCATTAAATTGCAAATTTGGGATACAGCA
GGCCAAGAAAGGTTCCGCTCTGTGACAAAATCTTACTATCGGAAAGCAGT
TGGTGCTTTGCTGGTGTATGATGTGAGCGACCGGGAATCATTTAATGGTC
TCAGTAAATGGCTGATTGATGTGAAACAGCTCAGTGGTGATGGGATCATT
GTCATTTTAGTTGGCAACAAAATTGACAGGCCCGACGAGTCACGGGAAGT
TTCATTTGTCGAAGGAACTCAATTTGCCCAGGAGAATGAGCTCATGTTCA
TTGAGACATCGGCAGTGACCGGTGAAAATGTTTCAGAGGCATTTATCAAT
GTTGCCCGACGAATTCTACACAATCTCGAAACAGTTTTAGATCATCCAGT
TGATGATGTTAATGATTTCCGTTCCGCTGACATTCGAAGGCCTTATTTAC
GCACACCGACTGAATCGTGCCGGTGTTGAAATGTCACCAATGAAATATTC
TCGTGGCTGTGATTGGATAGAATGTATACAAGCAAATAAATTAGCATGAC

protein sequence of SMED30001147-orf-1

>SMED30001147-orf-1 ID=SMED30001147-orf-1|Name=SMED30001147-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=208bp
MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTI
ELDGKTIKLQIWDTAGQERFRSVTKSYYRKAVGALLVYDVSDRESFNGLS
KWLIDVKQLSGDGIIVILVGNKIDRPDESREVSFVEGTQFAQENELMFIE
TSAVTGENVSEAFINVARRILHNLETVLDHPVDDVNDFRSADIRRPYLRT
PTESCRC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0000166	nucleotide binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR001806	Small_GTPase
IPR027417	P-loop_NTPase

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction
GO:0006810	transport
GO:0006914	autophagy
GO:0015031	protein transport

Vocabulary: **cellular component**
Term	Definition
GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0034045	pre-autophagosomal structure membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00449	RASTRNSFRMNG	coord: 9..30 score: 56.84 coord: 32..48 score: 35.4 coord: 50..60 score: 19.93
None	No IPR available	SMART	SM00175	rab_sub_5	coord: 9..60 e-value: 4.7E-4 score: -59.1
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 2..60 e-value: 1.4E-19 score: 72.1
None	No IPR available	PANTHER	PTHR24073	FAMILY NOT NAMED	coord: 3..60
None	No IPR available	PANTHER	PTHR24073:SF1096	RAS-RELATED PROTEIN RAB-1B	coord: 3..60
None	No IPR available	PROSITE	PS51419	RAB	coord: 4..60 score: 14.725
IPR001806	Small GTPase	PFAM	PF00071	Ras	coord: 10..60 e-value: 2.8E-17 score: 62.8
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 4..60