FERM domain-containing protein

Overview


Name	FERM domain-containing protein
Smed ID	SMED30001113
Length (bp)	5343

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of FERM domain-containing protein (SMED30001113) t-SNE clustered cells

Violin plots show distribution of expression levels for FERM domain-containing protein (SMED30001113) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FERM domain-containing protein (SMED30001113) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FERM domain-containing protein (SMED30001113) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001113

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30001113	h1SMcG0016365	dd_Smed_v4_5600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30001113	h1SMcG0016365	dd_Smed_v4_5600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30001113	h1SMcG0016365	dd_Smed_v4_5600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Human
Match: FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:HGNC Symbol;Acc:HGNC:16460])

HSP 1 Score: 319.316 bits (817), Expect = 1.499e-93
Identity = 150/328 (45.73%), Postives = 222/328 (67.68%), Query Frame = 3

Query:  102 RKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQ--PNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
            R   + +  R+ LLD+++  F I     G  L   + ++ N++E DYF +E+ N++    W+   K I++Q+   K++V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+  TAALL S+++Q+EIGD+  DE +D  +L+    VN+  P ++  L KI+EFH+ H+G +  E+DF +L+ ARK+E YG++ H+A D E   + L+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K   K     ++GSSFRY GRTQK+L++Y ++S
Sbjct:   38 RMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDY--DETLDREHLK----VNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKPKAKA-VFFSRGSSFRYSGRTQKQLVDYFKDS 358

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Human
Match: FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:HGNC Symbol;Acc:HGNC:16460])

HSP 1 Score: 319.316 bits (817), Expect = 2.182e-93
Identity = 150/328 (45.73%), Postives = 222/328 (67.68%), Query Frame = 3

Query:  102 RKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQ--PNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
            R   + +  R+ LLD+++  F I     G  L   + ++ N++E DYF +E+ N++    W+   K I++Q+   K++V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+  TAALL S+++Q+EIGD+  DE +D  +L+    VN+  P ++  L KI+EFH+ H+G +  E+DF +L+ ARK+E YG++ H+A D E   + L+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K   K     ++GSSFRY GRTQK+L++Y ++S
Sbjct:   38 RMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDY--DETLDREHLK----VNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKPKAKA-VFFSRGSSFRYSGRTQKQLVDYFKDS 358

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Human
Match: FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:HGNC Symbol;Acc:HGNC:16460])

HSP 1 Score: 317.39 bits (812), Expect = 3.326e-89
Identity = 150/328 (45.73%), Postives = 222/328 (67.68%), Query Frame = 3

Query:  102 RKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQ--PNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
            R   + +  R+ LLD+++  F I     G  L   + ++ N++E DYF +E+ N++    W+   K I++Q+   K++V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+  TAALL S+++Q+EIGD+  DE +D  +L+    VN+  P ++  L KI+EFH+ H+G +  E+DF +L+ ARK+E YG++ H+A D E   + L+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K  K      ++GSSFRY GRTQK+L++Y ++S
Sbjct:   38 RMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDY--DETLDREHLK----VNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKP-KAKAVFFSRGSSFRYSGRTQKQLVDYFKDS 358

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Human
Match: FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1 [Source:HGNC Symbol;Acc:HGNC:3591])

HSP 1 Score: 298.516 bits (763), Expect = 9.797e-85
Identity = 149/322 (46.27%), Postives = 214/322 (66.46%), Query Frame = 3

Query:  108 NNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRE 1073
            + + +  +I +LDD+   F +   A G  L  A+    N++E DYF LE+ + + +  W++  K IVKQ+   K +V  F VKF+      L+EE TRYLFALQ+K+D+  G+L C+  +AALL S+IVQ+EIGDF  DE +D  +L   K + Q  + + +KI+EFH  HIG +  E+DF LL+ AR++E YG+++H AKD E   +NL+V + G++VFQ  TKIN F+WAK+RKLSFKRK+FLIKL P+    Y+  +EF   +RD CK FWK C+EHHAFFR    E   K  P + ++GSSFR+ GRTQK++++YV+E
Sbjct:   36 SGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDF--DEALDREHLAKNKYIPQ-QDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRL-FEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKE 353

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Human
Match: FRMD7 (FERM domain containing 7 [Source:HGNC Symbol;Acc:HGNC:8079])

HSP 1 Score: 290.426 bits (742), Expect = 8.486e-83
Identity = 164/374 (43.85%), Postives = 216/374 (57.75%), Query Frame = 3

Query:  120 IQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDL 1238
            +  ++  LDDS   F ++  + G  LF       N+ E +YF LE+ +  G   W+   K I KQV   K++VF F VKF+   P  L EE TRYLF LQIK+D+  G+L CS N  AL+ S+I+Q+E+GDF   E  D  +L   + +  PN++ L  KIM FH+ HIG S  E+D  LLD ARK++ YG++ H A D E + ++L+V HMGV+V +  TKINTF+WAKIRKLSFKRK FLIKLH       K  +EF   +RD CK FWK C+E+HAFFR     KS  KT  + +KGSSFRY GRTQ++L+EY R              K R+   P   KH  +   YH    +SS    S       DL
Sbjct:    2 LHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDF--HEETDRKHLAQTRYL--PNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKT-LLCSKGSSFRYSGRTQRQLLEYGR--------------KGRLKSLPFERKH--YPSQYHERQCRSSPDLLSDVSKQVEDL 354

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Match: frm-3 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:G5EDC0])

HSP 1 Score: 365.155 bits (936), Expect = 2.077e-105
Identity = 172/344 (50.00%), Postives = 233/344 (67.73%), Query Frame = 3

Query:   99 SRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            S K  R +  ++ +LDD+V  F +   AIG  L   +    N+LE DYF L +++  G  CW++  K I++Q+  G  D  F F VKFYT +P  LEEEYTRYLF +QIKRD+  G+L CS NTA+LL++Y+VQ+E GDF  ++Y D +YL H + V     E   K+M+ H+  IGM+  E+D  +L+ AR+ ++YGVK+H AKD +     LSV H+G+ VF+ L    TFSWA+IRKLSFKRKK L+KLHP+ Y Y K  VEF FETRD+CK FWKKC+EHHAFFRC  +E+  K+T   ++KGSSFRY GRTQK+LI+YVRE +  +R+ F RP ++  S
Sbjct:   18 SSKRGRLVCIKVRMLDDTVAVFHLGHKAIGQTLLDEVCRHLNLLECDYFGLSFIDINGNHCWLDREKTILRQITNGSTDAKFYFVVKFYTPNPIDLEEEYTRYLFTMQIKRDLALGELHCSDNTASLLSAYLVQSECGDFSSEDYPDATYLSHTRFVPNQTLEFQKKVMDNHRNFIGMTPGESDLAMLEVARRCDFYGVKLHAAKDIDGNDAALSVMHLGIKVFRQLQLDTTFSWARIRKLSFKRKKLLVKLHPDSYQYLKETVEFSFETRDECKNFWKKCVEHHAFFRCVQAEEPKKETRFFISKGSSFRYHGRTQKQLIDYVRE-HHKRREPFTRPLRSAAS 360

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Match: frm-3 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:G5EDC0])

HSP 1 Score: 354.755 bits (909), Expect = 5.266e-102
Identity = 178/372 (47.85%), Postives = 242/372 (65.05%), Query Frame = 3

Query:   99 SRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRP--SKARVSKSPHNNKHA---------RHGKSYHP 1178
            S K  R +  ++ +LDD+V  F +   AIG  L   +    N+LE DYF L +++  G  CW++  K I++Q+  G  D  F F VKFYT +P  LEEEYTRYLF +QIKRD+  G+L CS NTA+LL++Y+VQ+E GDF  ++Y D +YL H + V     E   K+M+ H+  IGM+  E+D  +L+ AR+ ++YGVK+H AKD +     LSV H+G+ VF+ L    TFSWA+IRKLSFKRKK L+KLHP+ Y Y K  VEF FETRD+CK FWKKC+EHHAFFRC  +E+  K+T   ++KGSSFRY GRTQK+LI+YVRE +  +R+ F RP  S A   K  +++ +          R+G  Y P
Sbjct:   30 SSKRGRLVCIKVRMLDDTVAVFHLGHKAIGQTLLDEVCRHLNLLECDYFGLSFIDINGNHCWLDREKTILRQITNGSTDAKFYFVVKFYTPNPIDLEEEYTRYLFTMQIKRDLALGELHCSDNTASLLSAYLVQSECGDFSSEDYPDATYLSHTRFVPNQTLEFQKKVMDNHRNFIGMTPGESDLAMLEVARRCDFYGVKLHAAKDIDGNDAALSVMHLGIKVFRQLQLDTTFSWARIRKLSFKRKKLLVKLHPDSYQYLKETVEFSFETRDECKNFWKKCVEHHAFFRCVQAEEPKKETRFFISKGSSFRYHGRTQKQLIDYVRE-HHKRREPFTRPLRSAASTRKGTYSSTYGLVTDRPTKHRNGSVYEP 400

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93])

HSP 1 Score: 194.126 bits (492), Expect = 7.567e-52
Identity = 113/350 (32.29%), Postives = 184/350 (52.57%), Query Frame = 3

Query:   39 LLRAMCAE----RSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNL-LEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVE-----FYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELI 1058
            +LR++ A     R  +  +   +AS    + +Q ++ LLD +     +   A+G EL+  +    ++ E DYF L+Y +   V+ W++  K + KQV  G      F VKF+TS P+  L+EE TRY F LQIK+DI SG+L C    A  LA++ +Q+E+GD+ + E     ++   +   + +E++  +I+E +K   G +  +A+ + L+ AR IE YGV MH+ +  +     L +T  G++VF    KI  F W K++KL FK KK  + +  +      G ++     F+  +    K FWK  IE HAFFR  +      +  +    GS+F+Y GRT+ E I
Sbjct:   20 MLRSLSARFSRNRQQQQKSQTQDASFDTKKFVQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDLEERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIELAAFALQSELGDY-NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQTPAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGLFLWEKLQKLDFKNKKITLVVEEDADQSNNGQIQLHTFVFHLTSEKAAKHFWKCAIEQHAFFRLKSRPIQANRKIQFFRLGSTFKYRGRTEYETI 368

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93])

HSP 1 Score: 193.356 bits (490), Expect = 1.223e-51
Identity = 113/350 (32.29%), Postives = 184/350 (52.57%), Query Frame = 3

Query:   39 LLRAMCAE----RSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNL-LEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVE-----FYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELI 1058
            +LR++ A     R  +  +   +AS    + +Q ++ LLD +     +   A+G EL+  +    ++ E DYF L+Y +   V+ W++  K + KQV  G      F VKF+TS P+  L+EE TRY F LQIK+DI SG+L C    A  LA++ +Q+E+GD+ + E     ++   +   + +E++  +I+E +K   G +  +A+ + L+ AR IE YGV MH+ +  +     L +T  G++VF    KI  F W K++KL FK KK  + +  +      G ++     F+  +    K FWK  IE HAFFR  +      +  +    GS+F+Y GRT+ E I
Sbjct:    4 MLRSLSARFSRNRQQQQKSQTQDASFDTKKFVQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDLEERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIELAAFALQSELGDY-NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQTPAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGLFLWEKLQKLDFKNKKITLVVEEDADQSNNGQIQLHTFVFHLTSEKAAKHFWKCAIEQHAFFRLKSRPIQANRKIQFFRLGSTFKYRGRTEYETI 352

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Match: frm-2 (FERM domain (Protein4.1-ezrin-radixin-moesin) family [Source:UniProtKB/TrEMBL;Acc:Q9GP93])

HSP 1 Score: 193.356 bits (490), Expect = 1.223e-51
Identity = 113/350 (32.29%), Postives = 184/350 (52.57%), Query Frame = 3

Query:   39 LLRAMCAE----RSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNL-LEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVE-----FYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELI 1058
            +LR++ A     R  +  +   +AS    + +Q ++ LLD +     +   A+G EL+  +    ++ E DYF L+Y +   V+ W++  K + KQV  G      F VKF+TS P+  L+EE TRY F LQIK+DI SG+L C    A  LA++ +Q+E+GD+ + E     ++   +   + +E++  +I+E +K   G +  +A+ + L+ AR IE YGV MH+ +  +     L +T  G++VF    KI  F W K++KL FK KK  + +  +      G ++     F+  +    K FWK  IE HAFFR  +      +  +    GS+F+Y GRT+ E I
Sbjct:    4 MLRSLSARFSRNRQQQQKSQTQDASFDTKKFVQCKVLLLDGAHLNIVVPRNAVGSELYEEVFYSLDLEERDYFGLQYTDPFNVQHWLDPTKKVAKQVAIGPPFTLRFRVKFFTSEPSSNLKEELTRYQFFLQIKQDISSGRLQCPHQLAIELAAFALQSELGDY-NPELHTALFISEFRFHPEQDEKMEVEILERYKACRGQTPAQAELNYLNKARWIEMYGVDMHIVEGKDGNTYRLGLTPQGMLVFDGPQKIGLFLWEKLQKLDFKNKKITLVVEEDADQSNNGQIQLHTFVFHLTSEKAAKHFWKCAIEQHAFFRLKSRPIQANRKIQFFRLGSTFKYRGRTEYETI 352

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BLAST of FERM domain-containing protein vs. Ensembl Fly
Match: Cdep (gene:FBgn0265082 transcript:FBtr0336810)

HSP 1 Score: 392.504 bits (1007), Expect = 1.486e-122
Identity = 186/341 (54.55%), Postives = 247/341 (72.43%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVN-SEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
            S    +  +++  RI +LDDS+  F + + A+G  LF  +  + N+LEADYF LEY   S   + W++  K + +QVG    D V  F +KFYT  P  LEEEYTRYLF LQIKRD+ +G L C+ NTAAL+ASYIVQA  GDF+ ++Y D++YL   + V   +  +  KIME HK H+G S  EAD +LL+TAR+ E YG+KMH AKD E +PLNL+V HMG+ VFQN+T+INTFSWAKIRK+SFKRK+FL+KLHPEGYGYYK  VEF+FE R++CK FWKKC+E+H FFRC A + + ++  +V+++GSSFRY G+TQK++IE+VRE+Y  KR NF R
Sbjct:   59 STPRHRGGKKLTVRIQMLDDSITMFQVQAKALGRVLFEQVCRQLNLLEADYFGLEYQEVSTHTKYWLDLEKPMNRQVGLSLIDPVLRFCIKFYTPDPAQLEEEYTRYLFCLQIKRDLATGSLQCNDNTAALMASYIVQASCGDFVPEDYPDHTYLSSYRFVPNQDATMQRKIMENHKKHVGQSPAEADLNLLETARRCELYGMKMHPAKDVEGVPLNLAVAHMGITVFQNITRINTFSWAKIRKISFKRKRFLVKLHPEGYGYYKDTVEFFFEGRNECKNFWKKCVENHGFFRCTAVQNTPRRKTRVLSRGSSFRYSGKTQKQIIEFVRENY-VKRQNFQR 398

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BLAST of FERM domain-containing protein vs. Ensembl Fly
Match: Cdep (gene:FBgn0265082 transcript:FBtr0336812)

HSP 1 Score: 405.216 bits (1040), Expect = 3.713e-114
Identity = 185/336 (55.06%), Postives = 246/336 (73.21%), Query Frame = 3

Query:  105 KNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVN-SEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
            +  +++  RI +LDDS+  F + + A+G  LF  +  + N+LEADYF LEY   S   + W++  K + +QVG    D V  F +KFYT  P  LEEEYTRYLF LQIKRD+ +G L C+ NTAAL+ASYIVQA  GDF+ ++Y D++YL   + V   +  +  KIME HK H+G S  EAD +LL+TAR+ E YG+KMH AKD E +PLNL+V HMG+ VFQN+T+INTFSWAKIRK+SFKRK+FL+KLHPEGYGYYK  VEF+FE R++CK FWKKC+E+H FFRC A + + ++  +V+++GSSFRY G+TQK++IE+VRE+Y  KR NF R
Sbjct:   64 RGGKKLTVRIQMLDDSITMFQVQAKALGRVLFEQVCRQLNLLEADYFGLEYQEVSTHTKYWLDLEKPMNRQVGLSLIDPVLRFCIKFYTPDPAQLEEEYTRYLFCLQIKRDLATGSLQCNDNTAALMASYIVQASCGDFVPEDYPDHTYLSSYRFVPNQDATMQRKIMENHKKHVGQSPAEADLNLLETARRCELYGMKMHPAKDVEGVPLNLAVAHMGITVFQNITRINTFSWAKIRKISFKRKRFLVKLHPEGYGYYKDTVEFFFEGRNECKNFWKKCVENHGFFRCTAVQNTPRRKTRVLSRGSSFRYSGKTQKQIIEFVRENY-VKRQNFQR 398

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BLAST of FERM domain-containing protein vs. Ensembl Fly
Match: Cdep (gene:FBgn0265082 transcript:FBtr0336809)

HSP 1 Score: 392.119 bits (1006), Expect = 7.009e-114
Identity = 194/374 (51.87%), Postives = 258/374 (68.98%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVN-SEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSA 1205
            S    +  +++  RI +LDDS+  F + + A+G  LF  +  + N+LEADYF LEY   S   + W++  K + +QVG    D V  F +KFYT  P  LEEEYTRYLF LQIKRD+ +G L C+ NTAAL+ASYIVQA  GDF+ ++Y D++YL   + V   +  +  KIME HK H+G S  EAD +LL+TAR+ E YG+KMH AKD E +PLNL+V HMG+ VFQN+T+INTFSWAKIRK+SFKRK+FL+KLHPEGYGYYK  VEF+FE R++CK FWKKC+E+H FFRC A + + ++  +V+++GSSFRY G+TQK++IE+VRE+Y  KR NF R    R  + P N        +Y    + SS SA
Sbjct:   59 STPRHRGGKKLTVRIQMLDDSITMFQVQAKALGRVLFEQVCRQLNLLEADYFGLEYQEVSTHTKYWLDLEKPMNRQVGLSLIDPVLRFCIKFYTPDPAQLEEEYTRYLFCLQIKRDLATGSLQCNDNTAALMASYIVQASCGDFVPEDYPDHTYLSSYRFVPNQDATMQRKIMENHKKHVGQSPAEADLNLLETARRCELYGMKMHPAKDVEGVPLNLAVAHMGITVFQNITRINTFSWAKIRKISFKRKRFLVKLHPEGYGYYKDTVEFFFEGRNECKNFWKKCVENHGFFRCTAVQNTPRRKTRVLSRGSSFRYSGKTQKQIIEFVRENY-VKRQNFQRSQSFR--QGPLNASSRSQSHTY----VNSSISA 425

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BLAST of FERM domain-containing protein vs. Ensembl Fly
Match: Cdep (gene:FBgn0265082 transcript:FBtr0336811)

HSP 1 Score: 377.096 bits (967), Expect = 7.163e-109
Identity = 190/374 (50.80%), Postives = 254/374 (67.91%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVN-SEGVRCWINHNKCIVKQVGAGK-DMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSA 1205
            S    +  +++  RI +LDDS+  F + + A+G  LF  +  + N+LEADYF LEY   S   + W++  K + +QVG    D V  F +KFYT  P  LEEEYTRYLF LQIKRD+ +G L C+ NTAAL+ASYIVQA  GDF+ ++Y D++YL   + V   +  +  KIME HK H+G S  EAD +LL+TAR+ E YG+KMH AKD E +PLNL+V HMG+ VFQN+T+INTFSWAKIRK+SFKRK+FL+KLHPEGY      VEF+FE R++CK FWKKC+E+H FFRC A + + ++  +V+++GSSFRY G+TQK++IE+VRE+Y  KR NF R    R  + P N        +Y    + SS SA
Sbjct:   59 STPRHRGGKKLTVRIQMLDDSITMFQVQAKALGRVLFEQVCRQLNLLEADYFGLEYQEVSTHTKYWLDLEKPMNRQVGLSLIDPVLRFCIKFYTPDPAQLEEEYTRYLFCLQIKRDLATGSLQCNDNTAALMASYIVQASCGDFVPEDYPDHTYLSSYRFVPNQDATMQRKIMENHKKHVGQSPAEADLNLLETARRCELYGMKMHPAKDVEGVPLNLAVAHMGITVFQNITRINTFSWAKIRKISFKRKRFLVKLHPEGY----DTVEFFFEGRNECKNFWKKCVENHGFFRCTAVQNTPRRKTRVLSRGSSFRYSGKTQKQIIEFVRENY-VKRQNFQRSQSFR--QGPLNASSRSQSHTY----VNSSISA 421

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BLAST of FERM domain-containing protein vs. Ensembl Fly
Match: cora (gene:FBgn0010434 transcript:FBtr0301279)

HSP 1 Score: 241.121 bits (614), Expect = 1.140e-66
Identity = 121/309 (39.16%), Postives = 178/309 (57.61%), Query Frame = 3

Query:  126 ARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKE 1052
            AR+ LLD S+   SI+  AIG ++  +I    N++E DYF L Y      R W++  K + K           FAVKFY   P+ L+E+ TRY   LQ++ DI+ G+L C+  T ALL SY+VQ+E+GD+  +E    +YL+  K+      E+ +K+M+ HKTH G S  EA+ H L+ A+K+  YGV +H AKD E + + L V   G++V+++  +IN F+W KI K+S+KR  F IK+ P  +  Y+  + F        K+ WK C+EHH FFR    E  + K+      GS++RY GRTQ E
Sbjct:   34 ARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDT-WPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPE-PVSKSKMFPVFGSTYRYKGRTQAE 340

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Match: farp2 (FERM, RhoGEF and pleckstrin domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2993])

HSP 1 Score: 321.627 bits (823), Expect = 7.727e-91
Identity = 175/416 (42.07%), Postives = 259/416 (62.26%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYH--------PFAIKSSYS---APSRAVSDASDLDRTGMNNQTPHTPCKPKS 1292
            S+++    + +N+ +Q R+  LD++   + + S A G  L   +  + N++E+DYF LE+ N +    W++ +K IVKQV    + +F  +VKF+   P  L+EE+TRYLF+LQIKRD++ G+L C+ NTAALLAS++VQ+EIGD+  D+  D  +L+  KL+    E +  KIME H+ H G +  E+DF +L+ ARK+E +GV+ H A D E   +NL+V HMG+ VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHPE +G ++  +EF   +RD CK FWK C+EHH+FFR    +   K      ++GSSFRY GRTQK+L+EYVR+S   +     R SK R+S     +   +   S++        P +I +S+    APS ++  A   ++    +QT H P +  S
Sbjct:   37 SSAMGAGGKGHNKGLQIRVQGLDEAQEFYELESKADGQLLLSDVFRRINLIESDYFGLEFQNLQMNWVWLDPSKLIVKQVRRPMNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQIKRDLLDGRLSCTENTAALLASHLVQSEIGDY--DDLADREFLKMNKLL-PCQEHVQEKIMELHRRHTGQTPAESDFQVLEIARKLEMFGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDTLEFLMGSRDQCKIFWKNCVEHHSFFRL-LDQPQPKSKAIFFSRGSSFRYSGRTQKQLVEYVRDSGLRRTPYQRRNSKIRMSTRSLASDVPKQNLSFNDSLRTHIPPSSITASFQSLHAPSVSMR-AETPNQLLHLHQTQHQPLRAPS 447

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BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Match: FRMD7 (si:ch211-243g6.3 [Source:ZFIN;Acc:ZDB-GENE-121214-124])

HSP 1 Score: 282.337 bits (721), Expect = 7.657e-85
Identity = 153/314 (48.73%), Postives = 208/314 (66.24%), Query Frame = 3

Query:   96 ASRKN-NRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILN-KIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRY 1031
            A+RKN N +++ R+  LDDS   F +    +G + F  +     +LE +YF LE+ +  G   W+   K + KQ+    D+ F F VKF+   P  L++  TRYLFALQIK+D+ +G L C+ N+AALL S+I+QAEIGD+ DDE +D  +L + + V  PN+E L+ KI+ FHK + G +  E+D HLL+ ARK++ YG++ H A D E + +NL+VTHMGV+VFQ  TKINTFSWAKIRKLSFKRK FLIKLH E     +  VEF   +RD CK FWK C+E+HAFFR     KS +K+  + +KGSSFRY
Sbjct:   16 AARKNKNEKLRLRVIFLDDSERVFEVERKIMGSDFFNKVCGHLKLLEKEYFGLEFRHHNGSFVWLELLKPVAKQIKNTSDVAFHFIVKFFPPDPGQLQKGLTRYLFALQIKQDLSNGSLTCNDNSAALLVSHILQAEIGDY-DDE-LDAHHLENKQYV--PNQEYLDHKIIRFHKKNRGHTPGESDVHLLEVARKMDMYGIRPHPAHDGEGMRINLAVTHMGVLVFQGNTKINTFSWAKIRKLSFKRKHFLIKLHTETGPSRRDTVEFSMASRDVCKAFWKMCVEYHAFFRLTEEPKSHQKSI-LSSKGSSFRY 324

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Match: farp1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) [Source:ZFIN;Acc:ZDB-GENE-070424-163])

HSP 1 Score: 298.13 bits (762), Expect = 8.938e-85
Identity = 144/321 (44.86%), Postives = 214/321 (66.67%), Query Frame = 3

Query:  114 RQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
            RQI  R+ +LDD+   F ++  A G  LF  +    N++E DYF LE+ +   +  W++  K I+KQ+   K+++  F VKF+      L EE TRYLFALQIK D+  G+L C+ ++AALL ++IVQ+EIGDF  DE     +L + K + +  + +++KI+ +H+ H+G +  E+D+ LL+ AR++E YGV++H AKD E   L+L+V H GV+VFQ  TKIN F+W+K+RKLSFKRK+FLIKL P+     +  +EF   +RD CK FWK C+E+HAFFR    E   K  P + T+GSSFR+ GRTQ+++I+YV+++
Sbjct:   39 RQISIRVQMLDDTQEVFEVSQRAPGKALFDLVCSHLNLVEGDYFGLEFQDQRKMIVWLDLLKPILKQIRRPKNIILRFVVKFFPPDHTQLLEELTRYLFALQIKHDLACGRLTCNESSAALLVAHIVQSEIGDF--DEVQCKQHLLNNKYIPE-QDTLMDKIIGYHRKHVGQTPAESDYQLLEIARRLEMYGVRLHPAKDREGTRLSLAVAHSGVLVFQGHTKINAFNWSKVRKLSFKRKRFLIKLRPDLNSNCQDTLEFMMGSRDCCKVFWKICVEYHAFFRL-FEEPKPKPKPVLFTRGSSFRFSGRTQRQVIDYVKDT 355

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BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Match: frmd7 (FERM domain containing 7 [Source:ZFIN;Acc:ZDB-GENE-060825-67])

HSP 1 Score: 286.96 bits (733), Expect = 1.300e-82
Identity = 145/310 (46.77%), Postives = 204/310 (65.81%), Query Frame = 3

Query:  180 AIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNK-IMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
             +G + F ++     ++E +YF LE+ +  G   W+   K + KQ+    D++F F VKF+   P  L+ E TRYLFALQIK+D+ +G L CS N+AALL SY++QAEIGDF+++  +D  +L + + +  PN+++L+K IM FHK H G S  EAD  LL+ +RK++ YG++ H A D EN+ +NL+VTH GV+VFQ  TKINTFSWA +RKLSFKRK FLIKLH       K  VEF    RD CK FWK C+E+H FFR     KS +K+  + ++GS FRY GRTQK+L+++ ++S       F+R
Sbjct:    3 VLGKDFFNSVCGHLKLVEKEYFGLEFRHHCGSYVWLELLKPLAKQIKRRNDLIFRFIVKFFPPDPGELQREVTRYLFALQIKQDLSNGSLTCSDNSAALLVSYLLQAEIGDFIEE--LDKQHLENKRYI--PNQDVLHKKIMRFHKRHRGQSPAEADHQLLEVSRKLDMYGIRPHAATDGENMRINLAVTHCGVLVFQGNTKINTFSWANVRKLSFKRKHFLIKLHTTIVASCKDTVEFTMANRDVCKAFWKMCVEYHTFFRLSQEPKSKQKS-LLYSRGSCFRYSGRTQKQLLDFTKKSEEKINLPFMR 307

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Match: farp1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) [Source:ZFIN;Acc:ZDB-GENE-070424-163])

HSP 1 Score: 290.812 bits (743), Expect = 1.071e-80
Identity = 144/322 (44.72%), Postives = 214/322 (66.46%), Query Frame = 3

Query:  111 NRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
             RQI  R+ +LDD+   F ++  A G  LF  +    N++E DYF LE+ +   +  W++  K I+KQ+   K+++  F VKF+      L EE TRYLFALQIK D+  G+L C+ ++AALL ++IVQ+EIGDF  DE     +L + K + +  + +++KI+ +H+ H+G +  E+D+ LL+ AR++E YGV++H AKD E   L+L+V H GV+VFQ  TKIN F+W+K+RKLSFKRK+FLIKL P+     +  +EF   +RD CK FWK C+E+HAFFR    E   K  P + T+GSSFR+ GRTQ+++I+YV+++
Sbjct:   38 GRQISIRVQMLDDTQEVFEVSQRAPGKALFDLVCSHLNLVEGDYFGLEFQDQRKMIVWLDLLKPILKQIRRPKNIILRFVVKFFPPDHTQLLEELTRYLFALQIKHDLACGRLTCNESSAALLVAHIVQSEIGDF--DEVQCKQHLLNNKYIPE-QDTLMDKIIGYHRKHVGQTPAESDYQLLEIARRLEMYGVRLHPAKDREGTRLSLAVAHSGVLVFQGHTKINAFNWSKVRKLSFKRKRFLIKLRPDLNSNCQDTLEFMMGSRDCCKVFWKICVEYHAFFRL-FEEPKPKPKPVLFTRGSSFRFSGRTQRQVIDYVKDT 355

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BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:Xenbase;Acc:XB-GENE-1194420])

HSP 1 Score: 323.939 bits (829), Expect = 1.495e-96
Identity = 162/351 (46.15%), Postives = 230/351 (65.53%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRP-SKARVS 1127
            ST+ S + +  N +    + LLD S     I     G  L   +    N++E DYF +E+  ++    W+   K + KQ+   K+     AVKF+   P  L+EEYTRYLFALQIKRD+   +L+C  +T ALL S ++Q+EIGD+  D+ +   +L++   V Q    + ++IM++H+ HIGMS  +ADF +L+ AR+++ YG + HLA D E   +NLSV+HMGV+VFQ  TKINTF+W+KIRKLSFKR++FLIKLHPE +G Y+  +EF   +RD CKRFWK C+E+H+FFR    E   K  P ++++GSSFRY GRTQK+LI+Y+R+S S KR ++ R  SKARVS
Sbjct:   36 STAFSTSPKSQNHESYTNVLLLDSSTLPLEIGPKTTGQALLSQLFTHLNVVETDYFGIEFQTAQAQWVWLEPLKSVNKQLRKPKNAKLRLAVKFFPPDPGQLQEEYTRYLFALQIKRDLEEEKLVCFDSTTALLISLLLQSEIGDY--DQKVVQDHLQNTYYV-QRQHSLEDRIMKYHQQHIGMSPGDADFQILEIARRLDLYGTRFHLASDREGAKINLSVSHMGVLVFQGSTKINTFNWSKIRKLSFKRRRFLIKLHPEVHGPYQDALEFLLPSRDTCKRFWKICVEYHSFFRL-QDEPKPKSKPVLLSRGSSFRYSGRTQKQLIDYMRDS-SIKRPSYERRHSKARVS 381

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:Xenbase;Acc:XB-GENE-1194420])

HSP 1 Score: 326.25 bits (835), Expect = 4.463e-95
Identity = 162/351 (46.15%), Postives = 230/351 (65.53%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRP-SKARVS 1127
            ST+ S + +  N +    + LLD S     I     G  L   +    N++E DYF +E+  ++    W+   K + KQ+   K+     AVKF+   P  L+EEYTRYLFALQIKRD+   +L+C  +T ALL S ++Q+EIGD+  D+ +   +L++   V Q    + ++IM++H+ HIGMS  +ADF +L+ AR+++ YG + HLA D E   +NLSV+HMGV+VFQ  TKINTF+W+KIRKLSFKR++FLIKLHPE +G Y+  +EF   +RD CKRFWK C+E+H+FFR    E   K  P ++++GSSFRY GRTQK+LI+Y+R+S S KR ++ R  SKARVS
Sbjct:   36 STAFSTSPKSQNHESYTNVLLLDSSTLPLEIGPKTTGQALLSQLFTHLNVVETDYFGIEFQTAQAQWVWLEPLKSVNKQLRKPKNAKLRLAVKFFPPDPGQLQEEYTRYLFALQIKRDLEEEKLVCFDSTTALLISLLLQSEIGDY--DQKVVQDHLQNTYYV-QRQHSLEDRIMKYHQQHIGMSPGDADFQILEIARRLDLYGTRFHLASDREGAKINLSVSHMGVLVFQGSTKINTFNWSKIRKLSFKRRRFLIKLHPEVHGPYQDALEFLLPSRDTCKRFWKICVEYHSFFRL-QDEPKPKSKPVLLSRGSSFRYSGRTQKQLIDYMRDS-SIKRPSYERRHSKARVS 381

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:Xenbase;Acc:XB-GENE-1194420])

HSP 1 Score: 319.316 bits (817), Expect = 1.645e-93
Identity = 159/348 (45.69%), Postives = 226/348 (64.94%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKR---DNFVRPS 1112
            ST+ S + +  N +    + LLD S     I     G  L   +    N++E DYF +E+  ++    W+   K + KQ+   K+     AVKF+   P  L+EEYTRYLFALQIKRD+   +L+C  +T ALL S ++Q+EIGD+  D+ +   +L++   V Q    + ++IM++H+ HIGMS  +ADF +L+ AR+++ YG + HLA D E   +NLSV+HMGV+VFQ  TKINTF+W+KIRKLSFKR++FLIKLHPE +G Y+  +EF   +RD CKRFWK C+E+H+FFR    E   K  P ++++GSSFRY GRTQK+LI+Y+R+S S KR   + FV PS
Sbjct:   36 STAFSTSPKSQNHESYTNVLLLDSSTLPLEIGPKTTGQALLSQLFTHLNVVETDYFGIEFQTAQAQWVWLEPLKSVNKQLRKPKNAKLRLAVKFFPPDPGQLQEEYTRYLFALQIKRDLEEEKLVCFDSTTALLISLLLQSEIGDY--DQKVVQDHLQNTYYV-QRQHSLEDRIMKYHQQHIGMSPGDADFQILEIARRLDLYGTRFHLASDREGAKINLSVSHMGVLVFQGSTKINTFNWSKIRKLSFKRRRFLIKLHPEVHGPYQDALEFLLPSRDTCKRFWKICVEYHSFFRL-QDEPKPKSKPVLLSRGSSFRYSGRTQKQLIDYMRDS-SIKRPSYERFVLPS 378

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:Xenbase;Acc:XB-GENE-1194420])

HSP 1 Score: 312.768 bits (800), Expect = 1.063e-89
Identity = 159/348 (45.69%), Postives = 226/348 (64.94%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKR---DNFVRPS 1112
            ST+ S + +  N +    + LLD S     I     G  L   +    N++E DYF +E+  ++    W+   K + KQ+   K+     AVKF+   P  L+EEYTRYLFALQIKRD+   +L+C  +T ALL S ++Q+EIGD+  D+ +   +L++   V Q    + ++IM++H+ HIGMS  +ADF +L+ AR+++ YG + HLA D E   +NLSV+HMGV+VFQ  TKINTF+W+KIRKLSFKR++FLIKLHPE +G Y+  +EF   +RD CKRFWK C+E+H+FFR    E   K  P ++++GSSFRY GRTQK+LI+Y+R+S S KR   + FV PS
Sbjct:   36 STAFSTSPKSQNHESYTNVLLLDSSTLPLEIGPKTTGQALLSQLFTHLNVVETDYFGIEFQTAQAQWVWLEPLKSVNKQLRKPKNAKLRLAVKFFPPDPGQLQEEYTRYLFALQIKRDLEEEKLVCFDSTTALLISLLLQSEIGDY--DQKVVQDHLQNTYYV-QRQHSLEDRIMKYHQQHIGMSPGDADFQILEIARRLDLYGTRFHLASDREGAKINLSVSHMGVLVFQGSTKINTFNWSKIRKLSFKRRRFLIKLHPEVHGPYQDALEFLLPSRDTCKRFWKICVEYHSFFRL-QDEPKPKSKPVLLSRGSSFRYSGRTQKQLIDYMRDS-SIKRPSYERFVLPS 378

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Match: pdcd6ip (programmed cell death 6 interacting protein [Source:Xenbase;Acc:XB-GENE-1194420])

HSP 1 Score: 313.538 bits (802), Expect = 1.756e-89
Identity = 159/348 (45.69%), Postives = 226/348 (64.94%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKR---DNFVRPS 1112
            ST+ S + +  N +    + LLD S     I     G  L   +    N++E DYF +E+  ++    W+   K + KQ+   K+     AVKF+   P  L+EEYTRYLFALQIKRD+   +L+C  +T ALL S ++Q+EIGD+  D+ +   +L++   V Q    + ++IM++H+ HIGMS  +ADF +L+ AR+++ YG + HLA D E   +NLSV+HMGV+VFQ  TKINTF+W+KIRKLSFKR++FLIKLHPE +G Y+  +EF   +RD CKRFWK C+E+H+FFR    E   K  P ++++GSSFRY GRTQK+LI+Y+R+S S KR   + FV PS
Sbjct:   36 STAFSTSPKSQNHESYTNVLLLDSSTLPLEIGPKTTGQALLSQLFTHLNVVETDYFGIEFQTAQAQWVWLEPLKSVNKQLRKPKNAKLRLAVKFFPPDPGQLQEEYTRYLFALQIKRDLEEEKLVCFDSTTALLISLLLQSEIGDY--DQKVVQDHLQNTYYV-QRQHSLEDRIMKYHQQHIGMSPGDADFQILEIARRLDLYGTRFHLASDREGAKINLSVSHMGVLVFQGSTKINTFNWSKIRKLSFKRRRFLIKLHPEVHGPYQDALEFLLPSRDTCKRFWKICVEYHSFFRL-QDEPKPKSKPVLLSRGSSFRYSGRTQKQLIDYMRDS-SIKRPSYERFVLPS 378

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Match: Farp2 (FERM, RhoGEF and pleckstrin domain protein 2 [Source:MGI Symbol;Acc:MGI:2385126])

HSP 1 Score: 325.094 bits (832), Expect = 4.528e-94
Identity = 159/367 (43.32%), Postives = 233/367 (63.49%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAI 1187
            S + R   + ++ R+ LLD +V  F I     G  L   + +  N++E DYF LE+ N +    W+   K I++QV   K+ V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+ NTAALL S+++Q+EIGD+  DE +D  +L+  + +  PN+E  L KI++FH+ H G +  E+DF +L+ ARK+E YG++ H+A D E   +NL+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K  K      ++GSSFRY GRTQK+L++YV++                + + P+  +H++   S H   +
Sbjct:   34 SLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDY--DETLDREHLKANEYL--PNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKP-KAKAVFFSRGSSFRYSGRTQKQLVDYVKD--------------GGMKRIPYERRHSKTRTSLHALTV 381

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Match: Farp2 (FERM, RhoGEF and pleckstrin domain protein 2 [Source:MGI Symbol;Acc:MGI:2385126])

HSP 1 Score: 320.857 bits (821), Expect = 2.135e-90
Identity = 160/347 (46.11%), Postives = 228/347 (65.71%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            S + R   + ++ R+ LLD +V  F I     G  L   + +  N++E DYF LE+ N +    W+   K I++QV   K+ V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+ NTAALL S+++Q+EIGD+  DE +D  +L+  + +  PN+E  L KI++FH+ H G +  E+DF +L+ ARK+E YG++ H+A D E   +NL+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K  K      ++GSSFRY GRTQK+L++YV++    +     R SK R S
Sbjct:   34 SLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDY--DETLDREHLKANEYL--PNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKP-KAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTS 375

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Match: Farp1 (FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived) [Source:MGI Symbol;Acc:MGI:2446173])

HSP 1 Score: 291.967 bits (746), Expect = 5.864e-81
Identity = 150/322 (46.58%), Postives = 214/322 (66.46%), Query Frame = 3

Query:  108 NNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRE 1073
            + + +  +I +LDD+   F +   A G  LF A+    N++E DYF LE+ +   +  W++  K IVKQ+   K +V  F VKF+      L+EE TRYLFALQ+K+D+  G+L C+  +AALL S+IVQ+EIGDF  DE +D  +L   K V Q  + + ++IMEFH +H+G +  E+DF LL+ AR++E YG+++H AKD E   +NL+V + G++VFQ  TKIN F+WAK+RKLSFKRK+FLIKL P+    Y+  +EF    RD CK FWK C+EHHAFFR    E   K  P + ++GSSFR+ GRTQK++++YV+E
Sbjct:   36 SGKLMTVKIQMLDDTQEAFEVPQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDF--DEALDREHLAKNKYVPQ-QDALEDRIMEFHHSHVGQTPAESDFQLLEVARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMAGRDFCKSFWKICVEHHAFFRL-FEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKE 353

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Match: Frmd7 (FERM domain containing 7 [Source:MGI Symbol;Acc:MGI:2686379])

HSP 1 Score: 282.722 bits (722), Expect = 2.026e-80
Identity = 148/315 (46.98%), Postives = 200/315 (63.49%), Query Frame = 3

Query:  120 IQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEY 1064
            +  ++  LDDS   F ++  + G  LF       N+ E +YF LE+ +  G   W+   K I KQV   K++VF F VKF+   P  L EE TRYLF LQIK+D+  G+L CS N  AL+ S+I+Q+E+GDF  +E +    ++   L +Q + E  +KIM+FH+ HIG S  E+D  LLD ARK++ YG++   A D E + ++L+V HMGV+V +  TKINTF+WAKIRKLSFKRK FLIKLH       K  +EF   +RD CK FWK C+E+HAFFR     KS  KT  + +KGSSFRY GRTQ++L+EY
Sbjct:    2 LHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEVVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDF-HEETVRKHLVQTQYLPSQASLE--SKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKT-LLCSKGSSFRYSGRTQRQLLEY 312

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Match: Epb41l3 (erythrocyte membrane protein band 4.1 like 3 [Source:MGI Symbol;Acc:MGI:103008])

HSP 1 Score: 246.899 bits (629), Expect = 1.529e-67
Identity = 125/316 (39.56%), Postives = 184/316 (58.23%), Query Frame = 3

Query:  105 KNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKE 1052
            K  + +Q ++ LLD S +   ++  + G  LF  + E  N+LE DYF L Y ++E  + W++  K I KQ+ +G    F F VKFY   P  L E+ TRY   LQ++ DIVSG+L CS  T ALL SY VQ+E+GD+  DE   N Y+   +      +E+ +K++E HK+H GM+  EA+ H L+ A+K+  YGV +H AKD E + + L V   G++++++  +IN F+W K+ K+S+KR  F IK+ P  +  ++  + F        KR WK C+EHH FFR    E   K   K +T GS FRY GRTQ +
Sbjct:  113 KRPKSMQCKVTLLDGSEYGCDVDKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQIRSGA-WHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGSYTVQSELGDYDPDE-CGNDYISEFRFAPNHTKELEDKVIELHKSHRGMTPAEAEMHFLENAKKLSMYGVDLHHAKDSEGVEIMLGVCASGLLIYRDRLRINRFAWPKVLKISYKRNNFYIKIRPGEFEQFESTIGFKLPNHRAAKRLWKVCVEHHTFFRLLLPEAPPK---KFLTLGSKFRYSGRTQAQ 423

[Close]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q91VS8|FARP2_MOUSE (FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Mus musculus OX=10090 GN=Farp2 PE=1 SV=2)

HSP 1 Score: 320.857 bits (821), Expect = 1.493e-89
Identity = 160/347 (46.11%), Postives = 228/347 (65.71%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            S + R   + ++ R+ LLD +V  F I     G  L   + +  N++E DYF LE+ N +    W+   K I++QV   K+ V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+ NTAALL S+++Q+EIGD+  DE +D  +L+  + +  PN+E  L KI++FH+ H G +  E+DF +L+ ARK+E YG++ H+A D E   +NL+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K  K      ++GSSFRY GRTQK+L++YV++    +     R SK R S
Sbjct:   34 SLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDY--DETLDREHLKANEYL--PNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKP-KAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTS 375

[Close]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Match: sp|O94887|FARP2_HUMAN (FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3)

HSP 1 Score: 317.39 bits (812), Expect = 1.597e-88
Identity = 150/328 (45.73%), Postives = 222/328 (67.68%), Query Frame = 3

Query:  102 RKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQ--PNEE-ILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
            R   + +  R+ LLD+++  F I     G  L   + ++ N++E DYF +E+ N++    W+   K I++Q+   K++V   AVKF+   P  L+EEYTRYLFALQ+KRD++  +L C+  TAALL S+++Q+EIGD+  DE +D  +L+    VN+  P ++  L KI+EFH+ H+G +  E+DF +L+ ARK+E YG++ H+A D E   + L+V+HMGV+VFQ  TKINTF+W+K+RKLSFKRK+FLIKLHPE +G Y+  +EF   +RD+CK FWK C+E+H FFR     K  K      ++GSSFRY GRTQK+L++Y ++S
Sbjct:   38 RMQEKHLHLRVKLLDNTMEIFDIEPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDY--DETLDREHLK----VNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLLDQPKP-KAKAVFFSRGSSFRYSGRTQKQLVDYFKDS 358

[Close]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Match: sp|F1LYQ8|FARP1_RAT (FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Farp1 PE=1 SV=2)

HSP 1 Score: 307.375 bits (786), Expect = 3.270e-85
Identity = 150/322 (46.58%), Postives = 214/322 (66.46%), Query Frame = 3

Query:  108 NNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRE 1073
            + + +  +I +LDD+   F +   A G  LF A+    N++E DYF LE+ +   +  W++  K IVKQ+   K ++  F VKF+      L+EE TRYLFALQ+K+D+  G+L C+  +AALL S+IVQ+EIGDF  DE +D  +L   K V Q  + + +KI+EFH +HIG +  E+DF LL+ AR++E YG+++H AKD E   +NL+V + G++VFQ  TKIN F+WAK+RKLSFKRK+FLIKL P+    Y+  +EF    RD CK FWK C+EHHAFFR    E   K  P + ++GSSFR+ GRTQK++++YV+E
Sbjct:   36 SGKLMTVKIQMLDDTQEAFEVPQRAPGKVLFDAVCNHLNLVEGDYFGLEFPDHRKIVVWLDLLKPIVKQIRRPKHVLVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDF--DEALDREHLAKNKYVPQ-QDALEDKIVEFHHSHIGQTPAESDFQLLEVARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDVNSSYQDTLEFLMAGRDFCKSFWKICVEHHAFFRL-FEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKE 353

[Close]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZUT3|FRMD7_HUMAN (FERM domain-containing protein 7 OS=Homo sapiens OX=9606 GN=FRMD7 PE=1 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 4.075e-82
Identity = 164/374 (43.85%), Postives = 216/374 (57.75%), Query Frame = 3

Query:  120 IQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDL 1238
            +  ++  LDDS   F ++  + G  LF       N+ E +YF LE+ +  G   W+   K I KQV   K++VF F VKF+   P  L EE TRYLF LQIK+D+  G+L CS N  AL+ S+I+Q+E+GDF   E  D  +L   + +  PN++ L  KIM FH+ HIG S  E+D  LLD ARK++ YG++ H A D E + ++L+V HMGV+V +  TKINTF+WAKIRKLSFKRK FLIKLH       K  +EF   +RD CK FWK C+E+HAFFR     KS  KT  + +KGSSFRY GRTQ++L+EY R              K R+   P   KH  +   YH    +SS    S       DL
Sbjct:    2 LHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITKQVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSELGDF--HEETDRKHLAQTRYL--PNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPASDGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMASRDACKAFWKTCVEYHAFFRLSEEPKSKPKT-LLCSKGSSFRYSGRTQRQLLEYGR--------------KGRLKSLPFERKH--YPSQYHERQCRSSPDLLSDVSKQVEDL 354

[Close]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y4F1|FARP1_HUMAN (FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1)

HSP 1 Score: 291.967 bits (746), Expect = 3.567e-80
Identity = 149/322 (46.27%), Postives = 214/322 (66.46%), Query Frame = 3

Query:  108 NNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRE 1073
            + + +  +I +LDD+   F +   A G  L  A+    N++E DYF LE+ + + +  W++  K IVKQ+   K +V  F VKF+      L+EE TRYLFALQ+K+D+  G+L C+  +AALL S+IVQ+EIGDF  DE +D  +L   K + Q  + + +KI+EFH  HIG +  E+DF LL+ AR++E YG+++H AKD E   +NL+V + G++VFQ  TKIN F+WAK+RKLSFKRK+FLIKL P+    Y+  +EF   +RD CK FWK C+EHHAFFR    E   K  P + ++GSSFR+ GRTQK++++YV+E
Sbjct:   36 SGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDF--DEALDREHLAKNKYIPQ-QDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRL-FEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKE 353

[Close]

BLAST of FERM domain-containing protein vs. TrEMBL
Match: A0A5K3ESI8 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 478.789 bits (1231), Expect = 1.131e-140
Identity = 222/365 (60.82%), Postives = 287/365 (78.63%), Query Frame = 3

Query:   81 TSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSK----SPHNNKHARHG 1163
            T  +N   K  + I AR+  LD++ H+F +   A G EL++ +I K NILE+DYFDLEY+N +G+RCW++H + +V+Q+  G++ VF F VKFYT HPNLLEEEYTRYLFALQIKRD+++G LICS NTAALL SYIVQAEIGDF+ +EY D SYLR LK++++PN++ L ++M+FHK HIGMS T+ADF LLDTARK+E+YGV++H A+D E LP++LSVTH+G+ VFQNLTKIN+FSWAKIRKLSF+RK+FLIKLH   Y     ++EF F++RD+CKRFWKKCIEHHAFFRCP  E+S ++ PKVVTKGSSFRY GRTQKEL+ ++RE+ + +R  F RPS AR +     +  N  HAR G
Sbjct:    6 TEKNNTIEKKVKSINARVLHLDETSHSFDLQHHASGAELYLQVIRKFNILESDYFDLEYMNEDGIRCWVDHTRPLVRQISHGQEFVFRFCVKFYTPHPNLLEEEYTRYLFALQIKRDLITGILICSENTAALLGSYIVQAEIGDFIKEEYRDISYLRTLKILHEPNDDRLRRVMDFHKNHIGMSPTDADFALLDTARKVEFYGVRLHPARDVEGLPMSLSVTHLGLGVFQNLTKINSFSWAKIRKLSFRRKRFLIKLHSMDY----DVIEFLFDSRDNCKRFWKKCIEHHAFFRCPLQERSRQRRPKVVTKGSSFRYIGRTQKELVRFMREN-NLRRPPFERPSTARRAHPTMLTGPNYAHARMG 365

[Close]

BLAST of FERM domain-containing protein vs. TrEMBL
Match: A0A5K3ESA7 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 478.404 bits (1230), Expect = 4.160e-140
Identity = 222/365 (60.82%), Postives = 287/365 (78.63%), Query Frame = 3

Query:   81 TSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSK----SPHNNKHARHG 1163
            T  +N   K  + I AR+  LD++ H+F +   A G EL++ +I K NILE+DYFDLEY+N +G+RCW++H + +V+Q+  G++ VF F VKFYT HPNLLEEEYTRYLFALQIKRD+++G LICS NTAALL SYIVQAEIGDF+ +EY D SYLR LK++++PN++ L ++M+FHK HIGMS T+ADF LLDTARK+E+YGV++H A+D E LP++LSVTH+G+ VFQNLTKIN+FSWAKIRKLSF+RK+FLIKLH   Y     ++EF F++RD+CKRFWKKCIEHHAFFRCP  E+S ++ PKVVTKGSSFRY GRTQKEL+ ++RE+ + +R  F RPS AR +     +  N  HAR G
Sbjct:    6 TEKNNTIEKKVKSINARVLHLDETSHSFDLQHHASGAELYLQVIRKFNILESDYFDLEYMNEDGIRCWVDHTRPLVRQISHGQEFVFRFCVKFYTPHPNLLEEEYTRYLFALQIKRDLITGILICSENTAALLGSYIVQAEIGDFIKEEYRDISYLRTLKILHEPNDDRLRRVMDFHKNHIGMSPTDADFALLDTARKVEFYGVRLHPARDVEGLPMSLSVTHLGLGVFQNLTKINSFSWAKIRKLSFRRKRFLIKLHSMDY----DVIEFLFDSRDNCKRFWKKCIEHHAFFRCPLQERSRQRRPKVVTKGSSFRYIGRTQKELVRFMREN-NLRRPPFERPSTARRAHPTMLTGPNYAHARMG 365

[Close]

BLAST of FERM domain-containing protein vs. TrEMBL
Match: G4VQ53 (Putative 4.1 G protein OS=Schistosoma mansoni OX=6183 GN=Smp_024070 PE=4 SV=1)

HSP 1 Score: 445.277 bits (1144), Expect = 4.222e-139
Identity = 204/337 (60.53%), Postives = 267/337 (79.23%), Query Frame = 3

Query:  105 KNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSK 1115
            K  R IQ  +  LDD++HTF I+  ++G ELF  ++++  +LEADYFDLEYVN EG+RCW++HNK I++Q    +D ++ F+VKFYT HPNLLEE YTRYLFALQIKRD+V+G L+CS NTAALLASYIVQAEIGDF+ +EY   SYL+ LKL+++PN+E L ++ EFHK+H+G++ TEADF LLDTARKIE+YGV++H A+DHE L LNL+VTH+G++VFQNL K+NTFSWAKIRKLSFKRK+FL+KLHPE Y      +EF F++RD+CK+FWKK IEHH FFRC   ++ L++  ++ + GSSFRY GRT++EL EYV+ +   KR  F R  K
Sbjct:    8 KGLRMIQVHVLHLDDTIHTFQISGHSLGEELFATVVDRFRLLEADYFDLEYVNDEGLRCWLDHNKTILRQYSTNRDFIYRFSVKFYTPHPNLLEEAYTRYLFALQIKRDLVTGTLLCSENTAALLASYIVQAEIGDFIQEEYRTISYLKSLKLLHEPNDERLRRVREFHKSHVGLTPTEADFALLDTARKIEFYGVRLHFARDHEGLALNLAVTHLGLLVFQNLIKVNTFSWAKIRKLSFKRKRFLVKLHPENY----DTIEFIFDSRDECKQFWKKSIEHHTFFRCTYPDRKLQRRSRLTSSGSSFRYLGRTEQELQEYVQRN-CEKRPPFERYGK 339

[Close]

BLAST of FERM domain-containing protein vs. TrEMBL
Match: A0A068WZE4 (Ezrin radixin moesin ERM OS=Echinococcus granulosus OX=6210 GN=EgrG_000706900 PE=4 SV=1)

HSP 1 Score: 489.189 bits (1258), Expect = 1.107e-138
Identity = 225/359 (62.67%), Postives = 288/359 (80.22%), Query Frame = 3

Query:   99 SRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSK----SPHNNKHARHG 1163
            + K  + I  R+  LD++VH FS+   A G +L++ +I K NILE+DYFDLE++N +G+RCW++H + +V+Q+  GKD+VF F VKFYT HPNLLEEEYTRYLFALQIKRD+V+G LICS NTAALL SYIVQAEIGDF+ +EY+D SYLR+LK++++PN++ L ++M+FHK HIGMS T+ADF LLDTARK+E+YGV++H A+D E LP++L+VTH+G+ VFQNLTKINTFSWAKIRKLSF+RK+FLIKLH   Y     ++EF F+TR+DCKRFWKKCIEHHAFFRCP  E+S ++ PKVVTKGSSFRY GRTQKELI ++RES + +R  F RPS AR +     +  N  HAR G
Sbjct:   11 AEKKVKTINVRVLHLDETVHDFSLLHHASGADLYVQVIRKFNILESDYFDLEFMNEDGIRCWLDHTRPLVRQIVHGKDLVFRFCVKFYTPHPNLLEEEYTRYLFALQIKRDLVTGVLICSENTAALLGSYIVQAEIGDFIKEEYLDISYLRNLKILHEPNDDRLRRVMDFHKNHIGMSPTDADFALLDTARKVEFYGVRLHPARDMEGLPMSLAVTHLGLSVFQNLTKINTFSWAKIRKLSFRRKRFLIKLHSMDY----DVIEFLFDTRNDCKRFWKKCIEHHAFFRCPLQERSSQRRPKVVTKGSSFRYIGRTQKELIRFMRES-NVRRPPFKRPSTARRAHPTMLTGPNYAHARMG 364

[Close]

BLAST of FERM domain-containing protein vs. TrEMBL
Match: A0A068YBG4 (Ezrin radixin moesin ERM OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000706900 PE=4 SV=1)

HSP 1 Score: 486.493 bits (1251), Expect = 1.008e-137
Identity = 225/362 (62.15%), Postives = 288/362 (79.56%), Query Frame = 3

Query:   90 SNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSK----SPHNNKHARHG 1163
            + A  K  + I  R+  LD++VH  S+   A G +L++ +I K NILE+DYFDLE++N +G+RCW++H + +V+Q+  GKD+VF F VKFYT HPNLLEEEYTRYLFALQIKRD+V+G LICS NTAALL SYIVQAEIGDF+ +EY+D SYLR+LK++ +PN++ L ++M+FHK HIGMS T+ADF LLDTARK+E+YGV++H A+D E LP++L+VTH+G+ VFQNLTKINTFSWAKIRKLSF+RK+FLIKLH   Y     ++EF F+TR+DCKRFWKKCIEHHAFFRCP  E+S ++ PKVVTKGSSFRY GRTQKELI ++RES + +R  F RPS+AR +     +  N  HAR G
Sbjct:    9 TTAIEKKVKIINVRVLHLDETVHDLSLLHHASGADLYVQVIRKFNILESDYFDLEFMNEDGIRCWLDHTRPLVRQIVHGKDLVFRFCVKFYTPHPNLLEEEYTRYLFALQIKRDLVTGVLICSENTAALLGSYIVQAEIGDFIKEEYLDISYLRNLKILYEPNDDRLRRVMDFHKNHIGMSPTDADFALLDTARKVEFYGVRLHPARDMEGLPMSLAVTHLGLSVFQNLTKINTFSWAKIRKLSFRRKRFLIKLHSMDY----DVIEFLFDTRNDCKRFWKKCIEHHAFFRCPLQERSSQRRPKVVTKGSSFRYIGRTQKELIRFMRES-NVRRPPFERPSRARRAHPTMLTGPNYAHARMG 365

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:103028790])

HSP 1 Score: 327.791 bits (839), Expect = 2.523e-93
Identity = 165/351 (47.01%), Postives = 238/351 (67.81%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            ST++ +  + + + +Q R+  LDD+   F + S A G  +   +  + N++E+DYF LE+ N +    W+   K IVKQV    + +F  +VKF+   P  L+EE+TRYLF+LQ+KRD++ G+L C+ NTAALLAS++VQ+EIGD+  DE  D  +L+  KL+  P++E L +KIME H+ H+G +  E+DF +L+ ARK+E YG++ H A D E   +NLSV HMG++VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHP+ +G ++  +EF   +RD CK FWK C+EHH+FFR    +   K    + T+GSSFRY GRTQK+L++YVR+S   +     R SK R+S
Sbjct:   36 STAMGSGGKGHCKGLQIRVQGLDDAQEFFDLESKADGQTVLTDVYRRINLIESDYFGLEFQNLQMNWVWLEPTKLIVKQVRRPVNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQMKRDLMEGRLYCTENTAALLASHLVQSEIGDY--DEVADREFLKLNKLL--PHQEHLQDKIMELHRRHLGQTPAESDFQVLEIARKLEMYGIRFHPAADREGTKINLSVAHMGLLVFQGNTKINTFNWSKIRKLSFKRKRFLIKLHPDVHGPHRDTLEFLMASRDQCKIFWKSCVEHHSFFRL-LDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVRDSGLRRTSYQRRNSKIRMS 381

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:103028790])

HSP 1 Score: 327.02 bits (837), Expect = 1.200e-92
Identity = 165/351 (47.01%), Postives = 238/351 (67.81%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            ST++ +  + + + +Q R+  LDD+   F + S A G  +   +  + N++E+DYF LE+ N +    W+   K IVKQV    + +F  +VKF+   P  L+EE+TRYLF+LQ+KRD++ G+L C+ NTAALLAS++VQ+EIGD+  DE  D  +L+  KL+  P++E L +KIME H+ H+G +  E+DF +L+ ARK+E YG++ H A D E   +NLSV HMG++VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHP+ +G ++  +EF   +RD CK FWK C+EHH+FFR    +   K    + T+GSSFRY GRTQK+L++YVR+S   +     R SK R+S
Sbjct:   36 STAMGSGGKGHCKGLQIRVQGLDDAQEFFDLESKADGQTVLTDVYRRINLIESDYFGLEFQNLQMNWVWLEPTKLIVKQVRRPVNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQMKRDLMEGRLYCTENTAALLASHLVQSEIGDY--DEVADREFLKLNKLL--PHQEHLQDKIMELHRRHLGQTPAESDFQVLEIARKLEMYGIRFHPAADREGTKINLSVAHMGLLVFQGNTKINTFNWSKIRKLSFKRKRFLIKLHPDVHGPHRDTLEFLMASRDQCKIFWKSCVEHHSFFRL-LDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVRDSGLRRTSYQRRNSKIRMS 381

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:103028790])

HSP 1 Score: 327.02 bits (837), Expect = 1.306e-92
Identity = 165/351 (47.01%), Postives = 238/351 (67.81%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            ST++ +  + + + +Q R+  LDD+   F + S A G  +   +  + N++E+DYF LE+ N +    W+   K IVKQV    + +F  +VKF+   P  L+EE+TRYLF+LQ+KRD++ G+L C+ NTAALLAS++VQ+EIGD+  DE  D  +L+  KL+  P++E L +KIME H+ H+G +  E+DF +L+ ARK+E YG++ H A D E   +NLSV HMG++VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHP+ +G ++  +EF   +RD CK FWK C+EHH+FFR    +   K    + T+GSSFRY GRTQK+L++YVR+S   +     R SK R+S
Sbjct:   36 STAMGSGGKGHCKGLQIRVQGLDDAQEFFDLESKADGQTVLTDVYRRINLIESDYFGLEFQNLQMNWVWLEPTKLIVKQVRRPVNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQMKRDLMEGRLYCTENTAALLASHLVQSEIGDY--DEVADREFLKLNKLL--PHQEHLQDKIMELHRRHLGQTPAESDFQVLEIARKLEMYGIRFHPAADREGTKINLSVAHMGLLVFQGNTKINTFNWSKIRKLSFKRKRFLIKLHPDVHGPHRDTLEFLMASRDQCKIFWKSCVEHHSFFRL-LDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVRDSGLRRTSYQRRNSKIRMS 381

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BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:103028790])

HSP 1 Score: 326.635 bits (836), Expect = 1.667e-92
Identity = 165/351 (47.01%), Postives = 238/351 (67.81%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS 1127
            ST++ +  + + + +Q R+  LDD+   F + S A G  +   +  + N++E+DYF LE+ N +    W+   K IVKQV    + +F  +VKF+   P  L+EE+TRYLF+LQ+KRD++ G+L C+ NTAALLAS++VQ+EIGD+  DE  D  +L+  KL+  P++E L +KIME H+ H+G +  E+DF +L+ ARK+E YG++ H A D E   +NLSV HMG++VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHP+ +G ++  +EF   +RD CK FWK C+EHH+FFR    +   K    + T+GSSFRY GRTQK+L++YVR+S   +     R SK R+S
Sbjct:   36 STAMGSGGKGHCKGLQIRVQGLDDAQEFFDLESKADGQTVLTDVYRRINLIESDYFGLEFQNLQMNWVWLEPTKLIVKQVRRPVNTLFRLSVKFFPPDPGQLQEEFTRYLFSLQMKRDLMEGRLYCTENTAALLASHLVQSEIGDY--DEVADREFLKLNKLL--PHQEHLQDKIMELHRRHLGQTPAESDFQVLEIARKLEMYGIRFHPAADREGTKINLSVAHMGLLVFQGNTKINTFNWSKIRKLSFKRKRFLIKLHPDVHGPHRDTLEFLMASRDQCKIFWKSCVEHHSFFRL-LDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVRDSGLRRTSYQRRNSKIRMS 381

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BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-243g6.3 (FERM domain-containing protein 7-like [Source:NCBI gene;Acc:103043485])

HSP 1 Score: 298.516 bits (763), Expect = 5.939e-86
Identity = 159/328 (48.48%), Postives = 217/328 (66.16%), Query Frame = 3

Query:   93 NASRKNNRQIQAR--IFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILN-KIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYV 1067
            +A R+N R+ +AR  +  LDDS   F +    +G + F  +     +LE +YF LE+ +  G   W+   K + KQ+    D+ F F VKF+   P  L++  TRYLFALQIK+D+ +G L C+ N+AALL S+I+QAEIGD+  DE +D  +L + + V  PN+E L+ KI+ FHK H G +  ++D HLL+ ARK++ YG++ H A D E + +NL+VTHMGV+VFQ  TKINTFSWAKIRKLSFKR+ FLIKLH E     + MVEF   +RD CK FWK C+E+HAFFR  A E   ++   + +KGSSFRY GRTQK+L+E V
Sbjct:   12 SAQRQNPREGRARLRVIFLDDSERVFEVEQKILGCDFFNKVCGHLKLLEKEYFGLEFRHHNGSYVWLELLKPLAKQIKHTSDLAFQFIVKFFPPDPGQLQKGLTRYLFALQIKQDLSNGSLTCNDNSAALLVSHILQAEIGDY--DEELDAHHLENKQYV--PNQEYLDHKIIRFHKKHRGHTPAQSDVHLLEVARKLDMYGIRPHPAHDGEGMRINLAVTHMGVLVFQGNTKINTFSWAKIRKLSFKRRHFLIKLHTEAGPSRRDMVEFTMASRDICKTFWKMCVEYHAFFRL-AEEPKPQQKSLLSSKGSSFRYSGRTQKQLLECV 334

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Match: farp2 (FERM, RhoGEF and pleckstrin domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2993])

HSP 1 Score: 254.603 bits (649), Expect = 8.761e-70
Identity = 143/327 (43.73%), Postives = 213/327 (65.14%), Query Frame = 3

Query:  180 AIGHELFMAIIEKQNILEADYF--DLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYT-RYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEIL-NKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVV--TKGSSFRY--CGRTQKELIEYVRESYSSKRDNFVRPS-KARVSKS 1133
            A G  L   + +  N++E+DYF  +LE     G   W++  K I KQV   K++VF   VKF+    + L+EE T RY FALQ+++D+++G+L+ S  +++L+A+ ++QA++ D+  +E   +  LR ++ +  PN+E+L N+I+++H+   G+S  EAD  LL+ AR+ + YG+++H A D E   +NL+V + GV VFQN TKINTF+WAKIRKLSFKRK FL+K HP+  G Y+  +EF  + RD CK FWK C+E HAFFR    +   +  PK V  ++GSSFRY   GRTQK++  YVR+ + S+R  F R S K R S+S
Sbjct:    2 AEGIALLTTVYKYLNLVESDYFGLELEPYPKCGFTVWLDSQKPIAKQVKNTKNVVFKLGVKFFPEDSSQLQEEITSRYQFALQVRQDLLAGRLVASEMSSSLMAACLLQADVSDY--EEQRSSQQLREVQYL--PNQEVLANRILDYHRQFAGLSPAEADVQLLEIARRQDTYGLRLHQAYDKEGASINLAVGYSGVSVFQNTTKINTFNWAKIRKLSFKRKYFLVKFHPDIEGNYQDTLEFSMKGRDACKAFWKGCVESHAFFRL---QDPPRPKPKSVLFSRGSSFRYRLSGRTQKQVSMYVRD-HGSRRVQFERRSTKMRSSQS 320

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BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001312.1 (pep scaffold:Pmarinus_7.0:GL477231:34421:73675:-1 gene:ENSPMAG00000001156.1 transcript:ENSPMAT00000001312.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 243.817 bits (621), Expect = 1.718e-66
Identity = 156/489 (31.90%), Postives = 248/489 (50.72%), Query Frame = 3

Query:  132 IFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVN--SEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRC--PASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIK-SSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGS-------QKRARKGRKFIQVSRTGSSDEDDDDKRVTASE 1562
            I LLD++  T   N    G  L  A+    ++ E DYF L++ +  +E  R W++  K + KQ+      +F F VKF+ + P+ L+EEYTRY + LQ++ DI+  +L C  NTAALLASYIVQ+E+GD+ + E++   YL  L+ + +   +   ++ + HK H+GM+  +A+F+ L+ A+ +E+YGV++H A+D  N+ + + VT  GV V+ N  +I+ F W KI K+ FK K F ++L  E     + ++ F       CK  WK C+EHH FFR   PAS   L    +  + GS FRY GRT+ + ++Y +E  S++  NF R    R  +   + K      +    A +  + S PSR      D+  + +         +P S+ NL        A  S ++E   +  HR         L +     + L   + SG G        Q + R+ RK      +GS + D+ D R + SE
Sbjct:   33 INLLDNTAITLRANKSEAGKALLDAVFAHLDLAETDYFGLQFADDSTETPR-WLDPTKPLRKQIKRSSPYIFNFRVKFFVTDPSKLQEEYTRYHYFLQLRNDILEARLPCPHNTAALLASYIVQSELGDYSETEHLPG-YLSDLRFLPRQGLDFEKEVAKLHKQHVGMTPADAEFNYLNVAKNVEFYGVELHYARDQSNVEIMVGVTAGGVNVYNNGVRISNFPWIKIVKIFFKLKHFFVQLRKEQNETRENIIGFNLGNYRACKTLWKACVEHHTFFRMARPASPPHLGFLAQYFSLGSKFRYSGRTEMQTVQYGKER-SNRNRNFARSPSQRFPRRTISGKEWGSNAATAGSAERLETQSLPSRTPPGTPDISSSDLREGCEKR--RPSSVGNLAGL-----ATPSSQEEAASLNNHRRTGSSTTTPLHSLSLDLKSL-VGSASGEGQAPALPPKQPQQRRRRKEACPGGSGSQEADELDSRPSDSE 510

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BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450])

HSP 1 Score: 200.29 bits (508), Expect = 1.815e-56
Identity = 119/316 (37.66%), Postives = 172/316 (54.43%), Query Frame = 3

Query:  180 AIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYF--ETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRT--QKELIEYVRESYSSKRDNFVRPSK 1115
            A+G +LF  ++   +ILE DYF L++++S  V  W++H K I KQV  G    F   VKFY+S PN L EE TRYLF LQ+K+DI+SG+L C   TA  LA+Y +QAE+GD    E+ + + +   + +   +EE+   I+E  K   G +  +A+ + L+ A+ +E YGV MH  K  +    +L +T  GV+VF+   KI  F W KI +L FKR K  + +  +     +    F F  +    CK  WK  +EHHAFFR     K+       +  GS FR+ GRT  Q   +   R + S +R    RPSK
Sbjct:    3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDCDPVEH-NPALVSEFRFIPSQSEEMEEAILEKWKDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPSKTNADPSSFIRMGSRFRFSGRTEFQATKVSKARRTSSFER----RPSK 313

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450])

HSP 1 Score: 199.904 bits (507), Expect = 2.435e-56
Identity = 119/316 (37.66%), Postives = 172/316 (54.43%), Query Frame = 3

Query:  180 AIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYF--ETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRT--QKELIEYVRESYSSKRDNFVRPSK 1115
            A+G +LF  ++   +ILE DYF L++++S  V  W++H K I KQV  G    F   VKFY+S PN L EE TRYLF LQ+K+DI+SG+L C   TA  LA+Y +QAE+GD    E+ + + +   + +   +EE+   I+E  K   G +  +A+ + L+ A+ +E YGV MH  K  +    +L +T  GV+VF+   KI  F W KI +L FKR K  + +  +     +    F F  +    CK  WK  +EHHAFFR     K+       +  GS FR+ GRT  Q   +   R + S +R    RPSK
Sbjct:    3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDCDPVEH-NPALVSEFRFIPSQSEEMEEAILEKWKDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPSKTNADPSSFIRMGSRFRFSGRTEFQATKVSKARRTSSFER----RPSK 313

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Match: epb41l5 (erythrocyte membrane protein band 4.1 like 5 [Source:ZFIN;Acc:ZDB-GENE-030616-450])

HSP 1 Score: 199.519 bits (506), Expect = 4.196e-56
Identity = 119/316 (37.66%), Postives = 172/316 (54.43%), Query Frame = 3

Query:  180 AIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYF--ETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRT--QKELIEYVRESYSSKRDNFVRPSK 1115
            A+G +LF  ++   +ILE DYF L++++S  V  W++H K I KQV  G    F   VKFY+S PN L EE TRYLF LQ+K+DI+SG+L C   TA  LA+Y +QAE+GD    E+ + + +   + +   +EE+   I+E  K   G +  +A+ + L+ A+ +E YGV MH  K  +    +L +T  GV+VF+   KI  F W KI +L FKR K  + +  +     +    F F  +    CK  WK  +EHHAFFR     K+       +  GS FR+ GRT  Q   +   R + S +R    RPSK
Sbjct:    3 AVGQDLFDQVMYHLDILEVDYFGLQFMDSAQVSHWLDHTKNIRKQVKIGPPYCFHMRVKFYSSEPNNLHEELTRYLFVLQLKQDILSGKLECPFETAVQLATYSLQAELGDCDPVEH-NPALVSEFRFIPSQSEEMEEAILEKWKDCRGQTPAQAELNYLNKAKWLEMYGVDMHSVKGRDGNEYSLGLTPTGVLVFEGENKIGLFFWPKITRLDFKRTKLTLVVVEDDDQAKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPSKTNADPSSFIRMGSRFRFSGRTEFQATKVSKARRTSSFER----RPSK 313

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Match: EDO33626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRN5])

HSP 1 Score: 309.686 bits (792), Expect = 2.511e-86
Identity = 168/395 (42.53%), Postives = 241/395 (61.01%), Query Frame = 3

Query:  117 QIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVS--KSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASD--LDRTGMNNQTPHTPCKPK 1289
            Q   ++ +LDDSV  F I     G  L+  + E  N+ E +YF L Y +      W++  K I KQV     ++F F VKFYT+ P +L+EEYTRYLFALQ+K+D+V+G L CS +TAALLASY+VQ E+GDF D       YL   +   +   +   +I +FHK H  +S T+ D++LLD AR++E YGV ++ AKD +N+ L L+  +MG++VFQ+ +KINT SWAKIRKLSFKRK+FLIKLHPE +G+YK +VEF   +R+ CK FWK  I  HAFFR   S+   +  P+V ++GSS+R+ GRTQK++I+ +++S+ S+      PS  R    K+P  N      +S       S +  P  A S++ +  ++      Q P    KP+
Sbjct:   22 QTTVKVCMLDDSVVKFDIEPKVKGDILYKQVYEYLNLDEREYFGLSYYDKSDNLFWLDQLKPIKKQVKEIGKVLFRFCVKFYTADPAMLQEEYTRYLFALQVKKDLVNGGLKCSESTAALLASYVVQGELGDF-DTLSCRPGYLADFQFFPEQTVDSEARISDFHKQHRSLSPTDCDYNLLDVARRLEMYGVILYPAKDKDNVDLELAAANMGIIVFQSGSKINTLSWAKIRKLSFKRKRFLIKLHPEIFGHYKDVVEFQMASRNACKSFWKVAISTHAFFRQSESQSPPRHRPRVFSRGSSYRFSGRTQKQIIDSMQDSFRSQ------PSFQRTQSLKTPARNNLPHTSQSS-----ASGFPRPYNAYSESENRIVEPMPPQEQVPEQQEKPE 404

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Match: EDO44823 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUW8])

HSP 1 Score: 230.335 bits (586), Expect = 3.651e-62
Identity = 129/371 (34.77%), Postives = 204/371 (54.99%), Query Frame = 3

Query:   66 STEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSE-------GVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHAR 1157
            S  GS  ++     N ++I+  + LLDDS     ++  A G  L   +    +I E  YF L+YV+             W+  +K I KQ       +F F V+F+ S P+ L E+ TRY F LQIKRDI++G+L C  +TAA L+SYI+QAE+GD+    ++D  Y+   + +    ++   +  EFHK HIG +  +A+F+ L+ A+ ++ YGV +H AKDH+   L L V+ +G+ V+ N  KIN F W+KI K+ FKRK+F I++ P+   +   ++ F   T   CK  WK C+E+H+F+R    + + K   +V+  GS +RY G+T+ + IE  R +++      VR    R SK   +   +R
Sbjct:   18 SVRGS-ELARTGNTNPQKIRCVVELLDDSEFIIDVDKNAKGTVLLNEVFRHLDIQEKHYFGLQYVSDSPDNMVGGAKEQWLQDDKIIRKQKKGTPPYIFYFCVRFFVSDPSKLVEDLTRYYFYLQIKRDILTGRLPCLYDTAAELSSYILQAELGDYDPKLHLDG-YVSEFRFIPDQTDDFEERAAEFHKHHIGQTPADAEFNFLEVAKTLDLYGVDLHCAKDHDGTDLFLGVSALGLTVYHNKCKINFFPWSKIVKVCFKRKRFFIQIRPDWNEWTDNIIGFQMLTYRSCKNLWKVCVEYHSFYRTHYPKATEK---RVLRMGSKYRYKGKTEYQAIEESR-THARPEPKIVRTLSRRYSKRSDSGTWSR 382

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BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Match: EDO30224 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1E3])

HSP 1 Score: 207.994 bits (528), Expect = 1.767e-58
Identity = 116/304 (38.16%), Postives = 170/304 (55.92%), Query Frame = 3

Query:  147 DSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNS-EGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLH-PEGYGYYKGMVEFYFE--TRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQ 1046
            DS +   I+    G  LF  + +   + E +YF L Y++  +G   W+  ++ I +Q+G    + F FAVKFY  +P  L E+ TRY F LQ++ D++ G++ CS    ALLASY++QAE+GD   +E+ + +YL  LK   +   E+  KI  FH+ H+GM+ ++A+F  LD  RK+  YG  M+ A   E   + ++++  GV VFQN  +++ F W KI  + FK KKF + L  P    YYK     YF+  ++   KR WK C+EHHAFFR       L K       GS FRY GRTQ
Sbjct:   17 DSDYECPIDKTTKGDHLFDQVCDHIGLAEKEYFGLRYIDEKDGQFNWLEGDRSIKRQMGKAP-LHFYFAVKFYPENPTTLREDITRYQFVLQLREDLLKGRIQCSNPIHALLASYVMQAELGDLHPEEH-EVAYLSDLKFFPKQPPELRQKIEAFHRKHVGMTPSDAEFQYLDNVRKLPLYGRDMYQAWGDEGQAVTIAISAWGVEVFQNNRQMHRFVWPKIISIGFKSKKFSLTLRAPSEDDYYKSTT-IYFKCGSQRAAKRVWKVCVEHHAFFRL-KEPVPLPKNTNFFKIGSKFRYSGRTQ 316

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BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Match: EDO32045 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW61])

HSP 1 Score: 193.741 bits (491), Expect = 3.796e-55
Identity = 105/279 (37.63%), Postives = 154/279 (55.20%), Query Frame = 3

Query:  126 ARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFR 962
              I LLD+S     I     G E+   + +  N+LE DYF L ++       W++  K + KQ+ AG   +  F VKFY + PN L EE TRYLF LQ+KRDI  G   C  +   L++S+I+ AE+GDF D +     Y+   + V +  E++  KI + HK  IG+  + A++  LD A+ +E YGV +HL K  + +   +++   GVVV+ N T + T+ W KI K+ FK KKF   L+ +G    + +  FY   +  CK  WK C+EHHAFFR
Sbjct:   13 CHIVLLDESEFPIEITKSTKGFEVLEKVFDHLNLLERDYFGLRFIEKNTQSRWLDPMKSVTKQLKAGPPYLMYFCVKFYAADPNKLHEELTRYLFFLQVKRDIFQGSAPCEIHADTLISSFILLAELGDF-DYQSYTPGYVSEFRFVPKQTEDLEEKISDCHKRLIGVVPSVAEYMYLDKAKWLEMYGVDLHLVKGEDGVEYFVALKPAGVVVYHNKTAVGTYLWQKITKIDFKGKKF--SLNVQGKEDREYVYVFYLPNKSACKHLWKCCVEHHAFFR 288

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Match: EDO34391 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPH7])

HSP 1 Score: 185.267 bits (469), Expect = 3.717e-52
Identity = 102/285 (35.79%), Postives = 164/285 (57.54%), Query Frame = 3

Query:  111 NRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKD-MVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFR 962
            + +   +I LLDD+  T      A G  +F  + +  +++E DYF L YV+    R W++ +K ++KQ+ + K      F VKFY   P L+ EE TRY   LQIKRDI+ G+L+CS N  A L +YIVQAE+GD+ D E  +++Y+   ++V + +E++ NKI + H++  G   + A+ + LD  + ++ YGV  H  KD +N+ L L +T  G+ + ++  K++ F WA+I K S++ K F +++H +     K    F       CK  WK  +EHHAF+R
Sbjct:   11 DAEFVVKISLLDDTELTCEFRRDAKGQTVFDTVCKALDLVEKDYFGLRYVDDSKQRHWLDLSKSVIKQMKSLKPPFKLFFRVKFYALDPGLIHEEITRYQCFLQIKRDILHGRLLCSYNELAELGAYIVQAELGDY-DPEDQEDNYVSEFRIVPKQSEKLENKIADIHRSLSGQVPSVAEKNFLDKVKSLDMYGVDPHPCKDQDNVQLYLGLTPTGIAIIRDGKKVSGFEWAQIIKCSYEGKVFYVQVHKDD---RKANYGFRLPDPLACKHLWKCAVEHHAFYR 291

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:101173454])

HSP 1 Score: 328.561 bits (841), Expect = 1.311e-93
Identity = 161/343 (46.94%), Postives = 229/343 (66.76%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
            S ++ + S+   R +Q R+  LDDS   F I+  A G  L   +  + N++E+DYF LE+ N + +  W+   K I KQV    + +F  +VKF+   P  L+EEYTRYLF+LQ+KRD++ G+LICS NT ALLAS++VQ+EIGD+  D+  D  +L+   L+    +++   IME H+ H+G +  E+DF +L+ ARK+E YGV+ H A D E   +NL+V HMG+ VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHPE +G ++ ++EF   +RD CK FWK C+E+H+FFR    +   K    + T+GSSFRY GRTQK+L++YVRE+   KR  + R
Sbjct:   36 SGNMVSGSKSPGRGLQVRVKGLDDSQEFFDIDPKAFGQTLLTKVFLRGNLMESDYFGLEFQNMQMMWVWLEPTKPIAKQVRKPANTLFRLSVKFFPPDPGQLQEEYTRYLFSLQMKRDLMEGRLICSENTGALLASHLVQSEIGDY--DDVADRDFLKANSLLPY-QDKVQEIIMELHRRHLGQTPAESDFQILEIARKLEMYGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDILEFLMASRDQCKVFWKICVEYHSFFRL-FDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVREN-GPKRTPYQR 373

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:101173454])

HSP 1 Score: 327.02 bits (837), Expect = 1.041e-92
Identity = 161/343 (46.94%), Postives = 229/343 (66.76%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
            S ++ + S+   R +Q R+  LDDS   F I+  A G  L   +  + N++E+DYF LE+ N + +  W+   K I KQV    + +F  +VKF+   P  L+EEYTRYLF+LQ+KRD++ G+LICS NT ALLAS++VQ+EIGD+  D+  D  +L+   L+    +++   IME H+ H+G +  E+DF +L+ ARK+E YGV+ H A D E   +NL+V HMG+ VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHPE +G ++ ++EF   +RD CK FWK C+E+H+FFR    +   K    + T+GSSFRY GRTQK+L++YVRE+   KR  + R
Sbjct:   36 SGNMVSGSKSPGRGLQVRVKGLDDSQEFFDIDPKAFGQTLLTKVFLRGNLMESDYFGLEFQNMQMMWVWLEPTKPIAKQVRKPANTLFRLSVKFFPPDPGQLQEEYTRYLFSLQMKRDLMEGRLICSENTGALLASHLVQSEIGDY--DDVADRDFLKANSLLPY-QDKVQEIIMELHRRHLGQTPAESDFQILEIARKLEMYGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDILEFLMASRDQCKVFWKICVEYHSFFRL-FDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVREN-GPKRTPYQR 373

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Match: farp2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2 [Source:NCBI gene;Acc:101173454])

HSP 1 Score: 327.02 bits (837), Expect = 1.159e-92
Identity = 161/343 (46.94%), Postives = 229/343 (66.76%), Query Frame = 3

Query:   78 STSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVR 1106
            S ++ + S+   R +Q R+  LDDS   F I+  A G  L   +  + N++E+DYF LE+ N + +  W+   K I KQV    + +F  +VKF+   P  L+EEYTRYLF+LQ+KRD++ G+LICS NT ALLAS++VQ+EIGD+  D+  D  +L+   L+    +++   IME H+ H+G +  E+DF +L+ ARK+E YGV+ H A D E   +NL+V HMG+ VFQ  TKINTF+W+KIRKLSFKRK+FLIKLHPE +G ++ ++EF   +RD CK FWK C+E+H+FFR    +   K    + T+GSSFRY GRTQK+L++YVRE+   KR  + R
Sbjct:   36 SGNMVSGSKSPGRGLQVRVKGLDDSQEFFDIDPKAFGQTLLTKVFLRGNLMESDYFGLEFQNMQMMWVWLEPTKPIAKQVRKPANTLFRLSVKFFPPDPGQLQEEYTRYLFSLQMKRDLMEGRLICSENTGALLASHLVQSEIGDY--DDVADRDFLKANSLLPY-QDKVQEIIMELHRRHLGQTPAESDFQILEIARKLEMYGVRFHPAADREGTKINLAVAHMGLQVFQGHTKINTFNWSKIRKLSFKRKRFLIKLHPEVHGPHQDILEFLMASRDQCKVFWKICVEYHSFFRL-FDQPQPKSKAILFTRGSSFRYSGRTQKQLVDYVREN-GPKRTPYQR 373

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Match: FARP1 (FERM, ARHGEF and pleckstrin domain-containing protein 1 [Source:NCBI gene;Acc:101165518])

HSP 1 Score: 303.138 bits (775), Expect = 7.043e-85
Identity = 157/376 (41.76%), Postives = 229/376 (60.90%), Query Frame = 3

Query:  111 NRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDE----YIDNSYLRHLKLVNQPNE-EILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHAR--HGKSYHPFAIKSSYSAPSRA 1217
             RQ+  R+ +LDD+   F ++  A G  LF  +    N++E DYF LEY N + +  W++H K I KQ+   K  +  F+VKF+      L EE TRYLFALQIK+D+  G+L C+ ++AAL+ S+I+Q+EIGDF + +     ++N+Y+        P++  +++KIMEFH  HIG +  E+D+ +L+ ARK++ YG+++H AKD +   L+L+V H GV+VFQ  T+IN F+W+KIRKLSFKRK+FLIKL P+    Y+  +EF   +RD CK FWK C+EHHAFFR    E   K  P + T+GS FR+ GRTQK++I+YV+ES                 K P   KH+R  H     P      +  P+ +
Sbjct:   40 GRQVAIRVRMLDDTEEIFDVSQKASGKVLFDLVCSHMNLIEGDYFGLEYQNHQKMIVWLDHIKPIYKQLRRPKHAILKFSVKFFPPDHAQLLEELTRYLFALQIKQDLCCGRLTCNESSAALMISHIIQSEIGDFEESQCRSHLLNNNYI--------PDQMPLIDKIMEFHSKHIGQTPAESDYQMLEVARKLDMYGIRLHPAKDRDRTKLSLAVAHTGVLVFQRHTRINAFNWSKIRKLSFKRKRFLIKLKPDLNSSYQDTLEFLMASRDCCKVFWKICVEHHAFFRL-FEEPKPKPKPVLFTRGSYFRFSGRTQKQVIDYVKES--------------EFKKIPFERKHSRVQHNSHLSPLPSPQHHQVPTES 392

[Close]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Match: FARP1 (FERM, ARHGEF and pleckstrin domain-containing protein 1 [Source:NCBI gene;Acc:101165518])

HSP 1 Score: 302.368 bits (773), Expect = 1.279e-84
Identity = 149/327 (45.57%), Postives = 217/327 (66.36%), Query Frame = 3

Query:  111 NRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDE----YIDNSYLRHLKLVNQPNE-EILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRES 1076
             RQ+  R+ +LDD+   F ++  A G  LF  +    N++E DYF LEY N + +  W++H K I KQ+   K  +  F+VKF+      L EE TRYLFALQIK+D+  G+L C+ ++AAL+ S+I+Q+EIGDF + +     ++N+Y+        P++  +++KIMEFH  HIG +  E+D+ +L+ ARK++ YG+++H AKD +   L+L+V H GV+VFQ  T+IN F+W+KIRKLSFKRK+FLIKL P+    Y+  +EF   +RD CK FWK C+EHHAFFR    E   K  P + T+GS FR+ GRTQK++I+YV+ES
Sbjct:   40 GRQVAIRVRMLDDTEEIFDVSQKASGKVLFDLVCSHMNLIEGDYFGLEYQNHQKMIVWLDHIKPIYKQLRRPKHAILKFSVKFFPPDHAQLLEELTRYLFALQIKQDLCCGRLTCNESSAALMISHIIQSEIGDFEESQCRSHLLNNNYI--------PDQMPLIDKIMEFHSKHIGQTPAESDYQMLEVARKLDMYGIRLHPAKDRDRTKLSLAVAHTGVLVFQRHTRINAFNWSKIRKLSFKRKRFLIKLKPDLNSSYQDTLEFLMASRDCCKVFWKICVEHHAFFRL-FEEPKPKPKPVLFTRGSYFRFSGRTQKQVIDYVKES 357

[Close]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Match: SMESG000048801.1 (SMESG000048801.1)

HSP 1 Score: 3032.28 bits (7860), Expect = 0.000e+0
Identity = 1652/1658 (99.64%), Postives = 1652/1658 (99.64%), Query Frame = 3

Query:   51 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGS-FPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLXXXXXXXXXXXMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANXXXXXXXXXXIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLDLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPXXXXXXXLCRGHXXXXXXXXXXXXXGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCXXXXXXXXXXXXXDRVVIVDGSNNKHDDTVTXXXXXXXXXXXXLVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFAXXXXXXXXXXXXXXAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEXXXXXXXXXFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRXXXXXXXXXXXXXXXXXXXXXXGHYQAAPHTELILKEPIQXXXXXXXXXXXXXXDIEXXXXXXXASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSXXXXXXXXXXXXXXSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMKXXXXXXXVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 5021
            MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGS FPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLDLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK    G GVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE
Sbjct:    1 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGSSFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLDLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK----GGGVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 1654

[Close]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Match: SMESG000048801.1 (SMESG000048801.1)

HSP 1 Score: 3028.04 bits (7849), Expect = 0.000e+0
Identity = 1652/1659 (99.58%), Postives = 1652/1659 (99.58%), Query Frame = 3

Query:   51 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHG-SFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLXXXXXXXXXXXMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANXXXXXXXXXXIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLL-DLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPXXXXXXXLCRGHXXXXXXXXXXXXXGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCXXXXXXXXXXXXXDRVVIVDGSNNKHDDTVTXXXXXXXXXXXXLVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFAXXXXXXXXXXXXXXAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEXXXXXXXXXFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRXXXXXXXXXXXXXXXXXXXXXXGHYQAAPHTELILKEPIQXXXXXXXXXXXXXXDIEXXXXXXXASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSXXXXXXXXXXXXXXSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMKXXXXXXXVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 5021
            MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHG SFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLL DLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK    G GVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE
Sbjct:    1 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGSSFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLADLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK----GGGVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 1655

[Close]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Match: SMESG000048801.1 (SMESG000048801.1)

HSP 1 Score: 3021.49 bits (7832), Expect = 0.000e+0
Identity = 1652/1662 (99.40%), Postives = 1652/1662 (99.40%), Query Frame = 3

Query:   51 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSA---PSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGS-FPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLXXXXXXXXXXXMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANXXXXXXXXXXIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLL-DLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPXXXXXXXLCRGHXXXXXXXXXXXXXGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCXXXXXXXXXXXXXDRVVIVDGSNNKHDDTVTXXXXXXXXXXXXLVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFAXXXXXXXXXXXXXXAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEXXXXXXXXXFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRXXXXXXXXXXXXXXXXXXXXXXGHYQAAPHTELILKEPIQXXXXXXXXXXXXXXDIEXXXXXXXASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSXXXXXXXXXXXXXXSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMKXXXXXXXVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 5021
            MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSA   PSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGS FPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLL DLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK    G GVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE
Sbjct:    1 MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSADSAPSRAVSDASDLDRTGMNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLKDLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRVTASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIGGYGDLSDSDQHGSSFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQDPPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQMVDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKSVKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREEYMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMFVSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGDDEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLADLLPGNPVYLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNSSLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSGNSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGIDNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTVTEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQEYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYLRRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQPVDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPPFKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMCYESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSESGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIFDERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTTTSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDPVEEIIIPQHASLLYDPETSSSCDSPMK----GGGVLTVEASLTEGKEDNYACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSGEIVEETE 1658

[Close]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Match: SMESG000038155.1 (SMESG000038155.1)

HSP 1 Score: 436.032 bits (1120), Expect = 2.745e-127
Identity = 203/342 (59.36%), Postives = 259/342 (75.73%), Query Frame = 3

Query:  114 RQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRP-SKARVSKSP 1136
            + I  R+ LLDDSV  F ++  AIG  L+  +I K  +LE+DYFDLEY+N EGV CW++H K +VKQ    K+ +F F +KFY  +PN+LE+EYTRYLFALQIKRDI  G L C+ NT ALL ++I Q+EIGDFL+DEY D +YL  L+L  Q NEE L K+ME H+T +G S +EAD++LLDTARK+E YG+K+H A+DHENLPL L+V+H G+V+ QN  KIN FSWAK+RKLSFKRK+F IKLH EGYGY+K +VEF F +R++CK FWK+CIEHHAFFRC A ++  K+  KV++KGSS+RY GRTQK+L E VRE+ S KR  F R  S +RVS  P
Sbjct:   15 KYIGVRVTLLDDSVQHFHVSVRAIGQHLYNQVIAKLQLLESDYFDLEYINKEGVSCWLDHLKQVVKQCTQRKEYIFQFGIKFYAPYPNMLEDEYTRYLFALQIKRDIYQGHLQCNINTTALLLAFIAQSEIGDFLEDEYDDYTYLSSLRLTKQANEEFLMKVMECHRTLVGQSPSEADYNLLDTARKVESYGIKLHPARDHENLPLKLAVSHQGIVIHQNRIKINIFSWAKVRKLSFKRKRFYIKLHAEGYGYFKDIVEFIFNSRNECKNFWKQCIEHHAFFRCQAVKQGSKRRSKVLSKGSSYRYTGRTQKQLQECVRET-SYKRPQFERSLSMSRVSNIP 355

[Close]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Match: SMESG000038155.1 (SMESG000038155.1)

HSP 1 Score: 434.876 bits (1117), Expect = 8.278e-127
Identity = 203/342 (59.36%), Postives = 259/342 (75.73%), Query Frame = 3

Query:  114 RQIQARIFLLDDSVHTFSINSCAIGHELFMAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFAVKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQAEIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADFHLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSWAKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHHAFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNFVRP-SKARVSKSP 1136
            + I  R+ LLDDSV  F ++  AIG  L+  +I K  +LE+DYFDLEY+N EGV CW++H K +VKQ    K+ +F F +KFY  +PN+LE+EYTRYLFALQIKRDI  G L C+ NT ALL ++I Q+EIGDFL+DEY D +YL  L+L  Q NEE L K+ME H+T +G S +EAD++LLDTARK+E YG+K+H A+DHENLPL L+V+H G+V+ QN  KIN FSWAK+RKLSFKRK+F IKLH EGYGY+K +VEF F +R++CK FWK+CIEHHAFFRC A ++  K+  KV++KGSS+RY GRTQK+L E VRE+ S KR  F R  S +RVS  P
Sbjct:   15 KYIGVRVTLLDDSVQHFHVSVRAIGQHLYNQVIAKLQLLESDYFDLEYINKEGVSCWLDHLKQVVKQCTQRKEYIFQFGIKFYAPYPNMLEDEYTRYLFALQIKRDIYQGHLQCNINTTALLLAFIAQSEIGDFLEDEYDDYTYLSSLRLTKQANEEFLMKVMECHRTLVGQSPSEADYNLLDTARKVESYGIKLHPARDHENLPLKLAVSHQGIVIHQNRIKINIFSWAKVRKLSFKRKRFYIKLHAEGYGYFKDIVEFIFNSRNECKNFWKQCIEHHAFFRCQAVKQGSKRRSKVLSKGSSYRYTGRTQKQLQECVRET-SYKRPQFERSLSMSRVSNIP 355

The following BLAST results are available for this feature:

BLAST of FERM domain-containing protein vs. Ensembl Human
BLAST of FERM domain-containing protein vs. Ensembl Celegans
BLAST of FERM domain-containing protein vs. Ensembl Fly
BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
BLAST of FERM domain-containing protein vs. Ensembl Xenopus
BLAST of FERM domain-containing protein vs. Ensembl Mouse
BLAST of FERM domain-containing protein vs. UniProt/SwissProt
BLAST of FERM domain-containing protein vs. TrEMBL
BLAST of FERM domain-containing protein vs. Ensembl Cavefish
BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
BLAST of FERM domain-containing protein vs. Ensembl Yeast
BLAST of FERM domain-containing protein vs. Ensembl Nematostella
BLAST of FERM domain-containing protein vs. Ensembl Medaka
BLAST of FERM domain-containing protein vs. Planmine SMEST

BLAST of FERM domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FARP2	1.499e-93	45.73	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
FARP2	2.182e-93	45.73	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
FARP2	3.326e-89	45.73	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
FARP1	9.797e-85	46.27	FERM, ARH/RhoGEF and pleckstrin domain protein 1 [...	[more]
FRMD7	8.486e-83	43.85	FERM domain containing 7 [Source:HGNC Symbol;Acc:H...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
frm-3	2.077e-105	50.00	FERM domain (Protein4.1-ezrin-radixin-moesin) fami...	[more]
frm-3	5.266e-102	47.85	FERM domain (Protein4.1-ezrin-radixin-moesin) fami...	[more]
frm-2	7.567e-52	32.29	FERM domain (Protein4.1-ezrin-radixin-moesin) fami...	[more]
frm-2	1.223e-51	32.29	FERM domain (Protein4.1-ezrin-radixin-moesin) fami...	[more]
frm-2	1.223e-51	32.29	FERM domain (Protein4.1-ezrin-radixin-moesin) fami...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cdep	1.486e-122	54.55	gene:FBgn0265082 transcript:FBtr0336810	[more]
Cdep	3.713e-114	55.06	gene:FBgn0265082 transcript:FBtr0336812	[more]
Cdep	7.009e-114	51.87	gene:FBgn0265082 transcript:FBtr0336809	[more]
Cdep	7.163e-109	50.80	gene:FBgn0265082 transcript:FBtr0336811	[more]
cora	1.140e-66	39.16	gene:FBgn0010434 transcript:FBtr0301279	[more]

BLAST of FERM domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
farp2	7.727e-91	42.07	FERM, RhoGEF and pleckstrin domain protein 2 [Sour...	[more]
FRMD7	7.657e-85	48.73	si:ch211-243g6.3 [Source:ZFIN;Acc:ZDB-GENE-121214-...	[more]
farp1	8.938e-85	44.86	FERM, RhoGEF (ARHGEF) and pleckstrin domain protei...	[more]
frmd7	1.300e-82	46.77	FERM domain containing 7 [Source:ZFIN;Acc:ZDB-GENE...	[more]
farp1	1.071e-80	44.72	FERM, RhoGEF (ARHGEF) and pleckstrin domain protei...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pdcd6ip	1.495e-96	46.15	programmed cell death 6 interacting protein [Sourc...	[more]
pdcd6ip	4.463e-95	46.15	programmed cell death 6 interacting protein [Sourc...	[more]
pdcd6ip	1.645e-93	45.69	programmed cell death 6 interacting protein [Sourc...	[more]
pdcd6ip	1.063e-89	45.69	programmed cell death 6 interacting protein [Sourc...	[more]
pdcd6ip	1.756e-89	45.69	programmed cell death 6 interacting protein [Sourc...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Farp2	4.528e-94	43.32	FERM, RhoGEF and pleckstrin domain protein 2 [Sour...	[more]
Farp2	2.135e-90	46.11	FERM, RhoGEF and pleckstrin domain protein 2 [Sour...	[more]
Farp1	5.864e-81	46.58	FERM, RhoGEF (Arhgef) and pleckstrin domain protei...	[more]
Frmd7	2.026e-80	46.98	FERM domain containing 7 [Source:MGI Symbol;Acc:MG...	[more]
Epb41l3	1.529e-67	39.56	erythrocyte membrane protein band 4.1 like 3 [Sour...	[more]

BLAST of FERM domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q91VS8\|FARP2_MOUSE	1.493e-89	46.11	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]
sp\|O94887\|FARP2_HUMAN	1.597e-88	45.73	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]
sp\|F1LYQ8\|FARP1_RAT	3.270e-85	46.58	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]
sp\|Q6ZUT3\|FRMD7_HUMAN	4.075e-82	43.85	FERM domain-containing protein 7 OS=Homo sapiens O...	[more]
sp\|Q9Y4F1\|FARP1_HUMAN	3.567e-80	46.27	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]

BLAST of FERM domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5K3ESI8	1.131e-140	60.82	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
A0A5K3ESA7	4.160e-140	60.82	Uncharacterized protein OS=Mesocestoides corti OX=...	[more]
G4VQ53	4.222e-139	60.53	Putative 4.1 G protein OS=Schistosoma mansoni OX=6...	[more]
A0A068WZE4	1.107e-138	62.67	Ezrin radixin moesin ERM OS=Echinococcus granulosu...	[more]
A0A068YBG4	1.008e-137	62.15	Ezrin radixin moesin ERM OS=Echinococcus multilocu...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
farp2	2.523e-93	47.01	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
farp2	1.200e-92	47.01	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
farp2	1.306e-92	47.01	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
farp2	1.667e-92	47.01	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
si:ch211-243g6.3	5.939e-86	48.48	FERM domain-containing protein 7-like [Source:NCBI...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
farp2	8.761e-70	43.73	FERM, RhoGEF and pleckstrin domain protein 2 [Sour...	[more]
ENSPMAT00000001312.1	1.718e-66	31.90	pep scaffold:Pmarinus_7.0:GL477231:34421:73675:-1 ...	[more]
epb41l5	1.815e-56	37.66	erythrocyte membrane protein band 4.1 like 5 [Sour...	[more]
epb41l5	2.435e-56	37.66	erythrocyte membrane protein band 4.1 like 5 [Sour...	[more]
epb41l5	4.196e-56	37.66	erythrocyte membrane protein band 4.1 like 5 [Sour...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of FERM domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO33626	2.511e-86	42.53	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44823	3.651e-62	34.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30224	1.767e-58	38.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32045	3.796e-55	37.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34391	3.717e-52	35.79	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of FERM domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
farp2	1.311e-93	46.94	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
farp2	1.041e-92	46.94	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
farp2	1.159e-92	46.94	FERM, ARH/RhoGEF and pleckstrin domain protein 2 [...	[more]
FARP1	7.043e-85	41.76	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]
FARP1	1.279e-84	45.57	FERM, ARHGEF and pleckstrin domain-containing prot...	[more]

BLAST of FERM domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000048801.1	0.000e+0	99.64	SMESG000048801.1	[more]
SMESG000048801.1	0.000e+0	99.58	SMESG000048801.1	[more]
SMESG000048801.1	0.000e+0	99.40	SMESG000048801.1	[more]
SMESG000038155.1	2.745e-127	59.36	SMESG000038155.1	[more]
SMESG000038155.1	8.278e-127	59.36	SMESG000038155.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001113 ID=SMED30001113|Name=FERM domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5343bp
AAATTTAAATATATTTAGAAAAACTTAATTGTTTGTGATTATTACGCGCA
ATGTGTGCAGAAAGATCTACGGAAGGTAGTACAAGTGTTTCCAATGCATC
ACGTAAAAATAATCGTCAGATTCAAGCGAGAATTTTTCTTCTTGATGACA
GTGTTCATACATTTTCAATTAATAGCTGCGCAATAGGGCATGAATTGTTC
ATGGCAATTATTGAGAAACAAAATATTCTCGAAGCGGATTATTTTGATTT
AGAATACGTTAACAGTGAAGGTGTTAGATGTTGGATAAATCACAATAAAT
GTATTGTAAAACAAGTCGGTGCTGGTAAAGACATGGTGTTTATTTTTGCT
GTGAAATTTTACACTTCTCATCCTAATTTACTGGAAGAAGAATACACAAG
ATATTTGTTCGCTTTGCAAATCAAAAGAGATATTGTCAGTGGACAACTGA
TTTGCAGCACAAATACAGCAGCTTTGTTGGCATCCTATATTGTGCAAGCT
GAGATCGGGGATTTTCTCGATGATGAATATATCGACAACAGTTACTTGCG
GCATTTGAAGCTGGTAAATCAACCGAATGAGGAAATTCTCAATAAGATAA
TGGAATTTCATAAAACTCATATTGGCATGTCTGCTACGGAGGCGGACTTT
CATCTGCTCGACACGGCTAGGAAAATTGAATATTACGGTGTCAAAATGCA
TCTAGCAAAGGATCACGAGAACCTTCCATTGAACCTGTCCGTTACGCACA
TGGGTGTTGTGGTTTTTCAGAACTTGACTAAAATTAACACATTTTCCTGG
GCCAAAATCAGGAAATTAAGCTTCAAGCGTAAAAAATTTCTTATCAAGCT
CCATCCGGAAGGATATGGTTACTACAAGGGAATGGTGGAATTCTACTTTG
AGACTAGAGACGACTGTAAACGATTCTGGAAAAAATGCATTGAACATCAC
GCATTCTTTCGGTGCCCGGCGTCAGAAAAATCTCTGAAGAAAACTCCAAA
AGTCGTCACAAAAGGTTCATCATTTCGGTATTGCGGACGAACACAAAAAG
AATTAATAGAATATGTTAGAGAAAGTTATTCATCAAAACGGGACAATTTT
GTCAGACCAAGCAAAGCTAGAGTGTCGAAATCACCGCATAATAACAAACA
CGCGAGACATGGTAAATCTTATCACCCATTTGCAATCAAGAGTTCTTACA
GTGCTCCTAGCAGAGCGGTGAGCGATGCTAGTGATCTTGACCGCACAGGA
ATGAATAACCAAACTCCACATACTCCTTGTAAACCTAAATCGATAAATAA
TTTAACGAAAACCAGATGGAGCCAATCTGCTAGACAAAGTCCTCGGGATG
AAGGAAAAGACATGAAGGAACATCGAGATAGAGAGATCAGAGATTTGAAG
GATTTGAAAAATAATAAAGAGGTTGGTAGAGAGTTACCAACATCAACAAG
AAGTGGAACAGGATCACAAAAACGGGCTAGGAAAGGTAGAAAATTTATTC
AAGTATCAAGAACTGGAAGTAGTGATGAAGATGATGATGATAAACGAGTT
ACAGCATCTGAGATGTCACTCTCATCCAGTGGTCACTGGGATAACTCTGT
TAATGGTGGAATTGTGGATCATTTAAATGAGGATCCACTGCCTGCTCGTG
AAGCGTTTCGAGGTGGAGATCGTTTGTGTCGTCAGCGAGCCAGCATCGGT
GGTTATGGCGATTTATCCGACAGTGATCAACACGGCTCATTCCCAAATAA
TACTAATAATCACAGTAACCGCCTGAAGCCATTACGACAAGGATCTGAAC
CGATATCTCAAAATTCCCAATCACCACCAAGCCGGAAAGATCAACAAGAT
CCACCACAACGTGTGGTTTGCATCGATCAATATTGTACAAAACGGCCTAG
GCATCCAGAATCATTATCTCAGAACTTGCGACCTCTCGTCTCTTCCAAGC
GCTACAAATCTACTCCAAACGATGTCGCAGGAAATCCAAAACTGCAGATG
GTTGATCAGCTGGATTCAAGTGAGTTGCTATCGGATATCCCGTATGTACT
TCTTCGCCGCCACAAATCCAATGAACCATCGGCAGGTCCAGCTTCAGTTA
AATCAGCCAGTCAATCTCAACGATCTCTTGCTTCTAAATCGCTCAAATCG
GTAAAAGATAATTTAGATGGTGATCGTAATAAGGATGTAGGATTCGGTCG
AATTCGGCATAGCAAATCCCTCGATCGCCGATTGGCTGCAATGGATTCTA
GTCTTAGGCCGACAATGGCACCAAAATCTCCCAAACTTTTACGGGAAGAG
TACATGCAGAGTCAACGTCGCCATATATCAGACAGAGACACTATTGAGGC
CCTCAAAAATCAATTGCGGTCAGCTAGTTCTGTTCGTAGCGTCAGCCGCA
TGCCCAATGGGGACATTTCATTTCGTAGCCAAGCAACAGGTCCGATGTTT
GTGTCAGCATATCGACTACCGCCTGTGAACAATTTCTCTGCCAAAGATGA
TACAATGTCTCCACAAACATTTGATCTTGATCGGTTATACGGTAGATCCA
ACAGAGTTCGCAAAAAGGTTCCAATGGATTCGAATGCAAATGATGGGGAT
GATGAAGTCGATGCAGATGATATCAAAACTGGCAATAAAGCGAGAAAAAT
TGGCAAAGATTCTAACGCATTTAGTGATAGCGATGACAGCCAGCTACATG
AAACTGCTGATTTGGAATGTTTGTTGGATTTATTACCCGGCAATCCAGTT
TACCTTGATTCCTCCTGCAGCTCAGATGACGGAGAGTTTGACCTCAGTCC
GGATCGCTGTGGAAGACCTCGCAGCGTGTCTGAAAGCGAATTCAAATTGC
GAACTCCTCGATCGAGTCGGCGGAGCAGTTTGTGCAGAGGTCACAACAGC
AGTCTTTCTCTTACGGATTCCAGCTTCAATAGTGGCACCAGTTTCCAATC
GGAGGAGGAAGGCGACATCAGCGGATCGCCTTATTCCTTTCTAGCAGAGT
GTAGCCAGCAACATAACAAGGAGACAAAAAACGTGGAAGGATCGTCAGGT
AATTCTCCCCAGTTGCCTGACGATAATGTCCCTGATTGCCAATCAAGAAC
TGAAGCGGTCGATCTGCAGATTCTAGAAGCTCCGCAATTGGATGATTCTC
CCACTGAATCTGACACAAATCCAGAAATGGAATTGCAGGCTCCTGGAATC
GATAATATGAGTATTGATCGTGATGAATCTGGGTCATCTAATGAAGGAAG
TAATAAATGTGCGTTGTCCAGTGAAAGTGCTAGTGCTAGTGCTAGCTCTG
ATCGCGTGGTCATTGTAGATGGAAGTAACAATAAGCATGATGATACTGTA
ACTGAACAAGAAAATATCAACATAATACAGCCAAATATATTGGTAACCAG
TCCAACATCCACTCAGAATTCTGTAACTCAACTGCTTGAATCAATGCTCC
AGAAACGACTTGCTGGTTCTCCATTTGTCCGTACATCGACTCCAACTCAG
GAATATGAAATCAATGAATGCTCCTTGCATGGATCTACAGACAATATCCA
TCAGCACAAACCTGAATCCTTTCATCTAAAATCTGCAGCCAGTGTTCCTG
GCCTAGTCACAGGAAGAGTGTCACCTTATAGTCCATTGCCTAGTTACCTT
CGCCGTCCATTTGCTTCGTCCAGTTCTAGCAGTAGCTCGCCAACGTCATC
GATATCAGCTAAAAATACTAATCCATTTATCGGGATTTCTAATTCCAACA
ATCCGTTCACCAGTGACGCGATCAATGAGGCGGGGATATTTTCCCAGCCG
GTCGATAATTTCAATATTTCCAATCCAAACAACAACTATGAGCATCTATT
CGAGCAAAGCATGGTGTATAATTCCAAGGAGCCAACTCACAAACCCGCTA
GTGACGATTCTGTCTGTATTGAGCCTCCTTCTCCTCCACCTCCTCCTCCT
TTCAAGCTGGGGGGCAAAGATGATCTCGATCGAGCCCTGGTGTTTCTAAA
TGAGGGTGCTTTGTCATCGATATCGGTGGGAATAATGACACCAACCAATC
ACGAGCTGGCAGGCACATTCCAGGACACAGTCGAAGGAAACCTAATGTGT
TACGAGTCATCAGAATATACCAGTAGGCCCCAATCGTTGCCAGATGAAGA
GGAACCCGACGAGTATGTGTTGCCAAGTGACCATCGGAGTTTCTCTGAGG
ACACTTCCTCCTCGGCTTCCTCGTCCTCTTCATCTCAGGATTCCTCGGAG
TCTGGCCATTATCAGGCGGCTCCTCACACGGAATTGATATTGAAGGAGCC
AATCCAAGAGCACAGTGAATCTAGCACATCGGCAAGTGAAGGCAGTGAAG
ATATCGAACCATTTCCGCCGCCGCCACCAGCTTCAGATCTATTGATATTC
GATGAAAGAGACGAGGACATTTTCCAGCAGTTGGAAAACAGCACATTTGC
CGGAAGCCAGAATAACGATATCGATTATAATGTGCTACCGCAATTGGATT
GCATGAATTCTCCTACTGATTTTCCTCAACCTCCTCCGCCACTAACAACA
ACATCCGGCGGTTATTCTAAAGAAGAATTGAGTAGTAGTGAAGTGCCAAG
CCTATTTGCAGATGATTCAGCAGCTACTAGTGTAGCTCCTATTGAGGACG
ATCATCTGTCTGGAATTATAATTTCCTCTCCTGTCGGCCATGATGATCCT
GTTGAAGAAATTATAATACCTCAGCATGCCTCATTGCTCTATGATCCTGA
AACTAGCAGCAGCTGTGATTCTCCAATGAAAGGAGGAGGAGGAGGAATAG
GAGTGCTTACTGTTGAAGCGTCACTGACAGAGGGGAAAGAAGATAATTAC
GCGTGTCAGGACTCGGTGTTTTCGTTGCCATATGAATCCGGCCGAGTAGA
TTATGATTGTGGCCGCGTTTCATATGAAGATGCTTTTCCTCAAATGGATT
TCTCTCTATCCTCACTCGATCCCAAGCAGCTCAATTATCGATCTTCTGGC
GAAATTGTCGAAGAAACCGAATAGCAATTTCATCATATACTTGTATATCA
TGATGTATCATGACACCATCGATTAGTATTATTATTTGATATCGGGACTT
TGATTTCTTTGAGATTTTCTACTGTGATTGTTATTTGTGAACGTTGAGAA
TCTCGTTTTGTTTTCATTATCACTGCTTCTCGTTAAACATAATAATATGA
TTTGGATTGCTATTTGCTCTTTCTAGTGATTTGATTGGTTGATATTTATC
TATAATTGATATTATTTATGATTATGGAATATTATGGATGGCAGTTATCG
ATTATCATTATTGATTATTGGGAATTGTTAATAATATCGACTT

protein sequence of SMED30001113-orf-1

>SMED30001113-orf-1 ID=SMED30001113-orf-1|Name=SMED30001113-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1658bp
MCAERSTEGSTSVSNASRKNNRQIQARIFLLDDSVHTFSINSCAIGHELF
MAIIEKQNILEADYFDLEYVNSEGVRCWINHNKCIVKQVGAGKDMVFIFA
VKFYTSHPNLLEEEYTRYLFALQIKRDIVSGQLICSTNTAALLASYIVQA
EIGDFLDDEYIDNSYLRHLKLVNQPNEEILNKIMEFHKTHIGMSATEADF
HLLDTARKIEYYGVKMHLAKDHENLPLNLSVTHMGVVVFQNLTKINTFSW
AKIRKLSFKRKKFLIKLHPEGYGYYKGMVEFYFETRDDCKRFWKKCIEHH
AFFRCPASEKSLKKTPKVVTKGSSFRYCGRTQKELIEYVRESYSSKRDNF
VRPSKARVSKSPHNNKHARHGKSYHPFAIKSSYSAPSRAVSDASDLDRTG
MNNQTPHTPCKPKSINNLTKTRWSQSARQSPRDEGKDMKEHRDREIRDLK
DLKNNKEVGRELPTSTRSGTGSQKRARKGRKFIQVSRTGSSDEDDDDKRV
TASEMSLSSSGHWDNSVNGGIVDHLNEDPLPAREAFRGGDRLCRQRASIG
GYGDLSDSDQHGSFPNNTNNHSNRLKPLRQGSEPISQNSQSPPSRKDQQD
PPQRVVCIDQYCTKRPRHPESLSQNLRPLVSSKRYKSTPNDVAGNPKLQM
VDQLDSSELLSDIPYVLLRRHKSNEPSAGPASVKSASQSQRSLASKSLKS
VKDNLDGDRNKDVGFGRIRHSKSLDRRLAAMDSSLRPTMAPKSPKLLREE
YMQSQRRHISDRDTIEALKNQLRSASSVRSVSRMPNGDISFRSQATGPMF
VSAYRLPPVNNFSAKDDTMSPQTFDLDRLYGRSNRVRKKVPMDSNANDGD
DEVDADDIKTGNKARKIGKDSNAFSDSDDSQLHETADLECLLDLLPGNPV
YLDSSCSSDDGEFDLSPDRCGRPRSVSESEFKLRTPRSSRRSSLCRGHNS
SLSLTDSSFNSGTSFQSEEEGDISGSPYSFLAECSQQHNKETKNVEGSSG
NSPQLPDDNVPDCQSRTEAVDLQILEAPQLDDSPTESDTNPEMELQAPGI
DNMSIDRDESGSSNEGSNKCALSSESASASASSDRVVIVDGSNNKHDDTV
TEQENINIIQPNILVTSPTSTQNSVTQLLESMLQKRLAGSPFVRTSTPTQ
EYEINECSLHGSTDNIHQHKPESFHLKSAASVPGLVTGRVSPYSPLPSYL
RRPFASSSSSSSSPTSSISAKNTNPFIGISNSNNPFTSDAINEAGIFSQP
VDNFNISNPNNNYEHLFEQSMVYNSKEPTHKPASDDSVCIEPPSPPPPPP
FKLGGKDDLDRALVFLNEGALSSISVGIMTPTNHELAGTFQDTVEGNLMC
YESSEYTSRPQSLPDEEEPDEYVLPSDHRSFSEDTSSSASSSSSSQDSSE
SGHYQAAPHTELILKEPIQEHSESSTSASEGSEDIEPFPPPPPASDLLIF
DERDEDIFQQLENSTFAGSQNNDIDYNVLPQLDCMNSPTDFPQPPPPLTT
TSGGYSKEELSSSEVPSLFADDSAATSVAPIEDDHLSGIIISSPVGHDDP
VEEIIIPQHASLLYDPETSSSCDSPMKGGGGGIGVLTVEASLTEGKEDNY
ACQDSVFSLPYESGRVDYDCGRVSYEDAFPQMDFSLSSLDPKQLNYRSSG
EIVEETE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx

Vocabulary: **INTERPRO**
Term	Definition
IPR041788	FARP1/FARP2/FRMD7_FERM_C
IPR035963	FERM_2
IPR019749	Band_41_domain
IPR000798	Ez/rad/moesin-like
IPR014847	FERM-adjacent
IPR018980	FERM_PH-like_C
IPR018979	FERM_N
IPR019748	FERM_central
IPR014352	FERM/acyl-CoA-bd_prot_sf
IPR011993	PH-like_dom_sf
IPR000299	FERM_domain
IPR029071	Ubiquitin-like_domsf

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0019898	extrinsic component of membrane
GO:0005856	cytoskeleton

Vocabulary: **molecular function**
Term	Definition
GO:0008092	cytoskeletal protein binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019749	Band 4.1 domain	PRINTS	PR00935	BAND41	coord: 122..135 score: 45.39 coord: 135..155 score: 54.07 coord: 57..69 score: 35.74 coord: 197..213 score: 33.7
IPR019749	Band 4.1 domain	SMART	SM00295	B41_5	coord: 20..217 e-value: 2.3E-49 score: 180.0
IPR000798	Ezrin/radixin/moesin-like	PRINTS	PR00661	ERMFAMILY	coord: 88..107 score: 30.83 coord: 220..240 score: 23.02 coord: 37..56 score: 25.0 coord: 131..152 score: 46.46
IPR018980	FERM, C-terminal PH-like domain	SMART	SM01196	FERM_C_3	coord: 221..311 e-value: 2.1E-36 score: 137.0
IPR018980	FERM, C-terminal PH-like domain	PFAM	PF09380	FERM_C	coord: 221..310 e-value: 5.0E-24 score: 84.5
IPR014847	FERM adjacent (FA)	SMART	SM01195	FA_2	coord: 316..362 e-value: 5.6E-11 score: 52.5
IPR014847	FERM adjacent (FA)	PFAM	PF08736	FA	coord: 318..360 e-value: 1.1E-9 score: 38.2
IPR011993	PH-like domain superfamily	GENE3D	G3DSA:2.30.29.30		coord: 212..304 e-value: 4.2E-35 score: 122.0
IPR019748	FERM central domain	PFAM	PF00373	FERM_M	coord: 108..217 e-value: 1.0E-15 score: 58.2
IPR019748	FERM central domain	CDD	cd14473	FERM_B-lobe	coord: 116..208 e-value: 7.6677E-26 score: 101.169
IPR018979	FERM, N-terminal	PFAM	PF09379	FERM_N	coord: 28..88 e-value: 8.5E-10 score: 38.4
IPR014352	FERM/acyl-CoA-binding protein superfamily	GENE3D	G3DSA:1.20.80.10		coord: 103..209 e-value: 7.8E-34 score: 118.3
None	No IPR available	GENE3D	G3DSA:3.10.20.90		coord: 22..102 e-value: 8.5E-17 score: 62.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 674..706
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1057..1085
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1380..1406
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 625..649
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1026..1085
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 915..938
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1419..1457
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 557..599
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 400..426
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1362..1379
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1501..1517
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 427..460
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 987..1008
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1354..1407
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 349..378
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 487..502
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 915..950
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1486..1517
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 554..604
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 836..858
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 400..512
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 679..700
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 359..374
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 617..649
None	No IPR available	PANTHER	PTHR45858	FAMILY NOT NAMED	coord: 14..1152
None	No IPR available	CDD	cd17098	FERM_F1_FARP1_like	coord: 24..108 e-value: 5.66314E-30 score: 112.307
None	No IPR available	SUPERFAMILY	SSF50729	PH domain-like	coord: 210..351
IPR000299	FERM domain	PROSITE	PS50057	FERM_3	coord: 24..307 score: 66.745
IPR041788	FARP1/FARP2/FRMD7, FERM domain C-lobe	CDD	cd13193	FERM_C_FARP1-like	coord: 204..325 e-value: 7.05564E-73 score: 236.471
IPR029071	Ubiquitin-like domain superfamily	SUPERFAMILY	SSF54236	Ubiquitin-like	coord: 26..105
IPR035963	FERM superfamily, second domain	SUPERFAMILY	SSF47031	Second domain of FERM	coord: 107..212

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FERM domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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