Cathepsin L

Overview
NameCathepsin L
Smed IDSMED30001027
Length (bp)1243
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cathepsin L (SMED30001027) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L (SMED30001027) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cathepsin L (SMED30001027) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cathepsin L (SMED30001027) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30001027

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30001027h1SMcG0002130 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30001027h1SMcG0002130 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30001027h1SMcG0002130 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30001027h1SMcG0002130 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30001027h1SMcG0002129 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30001027h1SMcG0002129 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30001027h1SMcG0002129 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30001027h1SMcG0002129 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30001027h1SMcG0017311 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30001027h1SMcG0017311 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30001027h1SMcG0017311 Contig1264uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30001027h1SMcG0017311 Contig1264newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
cephalic gangliaSMED30001027h1SMcG0017311 dd_Smed_v4_2268_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30001027h1SMcG0017311 dd_Smed_v4_2268_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30001027h1SMcG0017311 Contig14109newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30001027h1SMcG0017311 Contig14109uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 242.662 bits (618), Expect = 1.318e-76
Identity = 126/281 (44.84%), Postives = 175/281 (62.28%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I  HN  + +G   F M +N   D T EEF Q+    +             +   LP+S DWR KG VT VKNQK CGSC+AFS TGALEGQ+FRKTG L+SLSEQ +VDC     + GC+GG +  AF Y+K +GG++SE+ YPYV+      +  C ++ + +V  DTGF  + PG E+AL +A+ T+GPIS+A  A    F+ YK+GIY +  CS+  ++H VL+VGYG +    + + YW++KNSWGP+WG NGY +  ++K N C +A  + YP V
Sbjct:   59 IELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVA-----VDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 242.662 bits (618), Expect = 1.318e-76
Identity = 126/281 (44.84%), Postives = 175/281 (62.28%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I  HN  + +G   F M +N   D T EEF Q+    +             +   LP+S DWR KG VT VKNQK CGSC+AFS TGALEGQ+FRKTG L+SLSEQ +VDC     + GC+GG +  AF Y+K +GG++SE+ YPYV+      +  C ++ + +V  DTGF  + PG E+AL +A+ T+GPIS+A  A    F+ YK+GIY +  CS+  ++H VL+VGYG +    + + YW++KNSWGP+WG NGY +  ++K N C +A  + YP V
Sbjct:   59 IELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVA-----VDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 233.417 bits (594), Expect = 4.171e-73
Identity = 135/331 (40.79%), Postives = 193/331 (58.31%), Query Frame = 3 
Query:  255 FSRKISSLMVDF----KSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            F   I+S  + F    ++++ K+K  + ++Y  + +E  R   +  +   I  HNQ + +G   F M +N   D T EEF Q +N  +             +    P S DWR+KG VT VKNQ  CGSC+AFS TGALEGQ+FRKTG LISLSEQ +VDC     + GC+GGL+  AF Y++ +GG++SE+ YPY     +    +C +  K +V  DTGFV +P   E+AL +A+ T+GPIS+A  A  E F  YK GIY +  CS+  ++H VL+VGYG +  E     YW++KNSWG +WG  GY +  ++ +N C +A  + YP V
Sbjct:   10 FCLGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY-----EATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 233.417 bits (594), Expect = 4.171e-73
Identity = 135/331 (40.79%), Postives = 193/331 (58.31%), Query Frame = 3 
Query:  255 FSRKISSLMVDF----KSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            F   I+S  + F    ++++ K+K  + ++Y  + +E  R   +  +   I  HNQ + +G   F M +N   D T EEF Q +N  +             +    P S DWR+KG VT VKNQ  CGSC+AFS TGALEGQ+FRKTG LISLSEQ +VDC     + GC+GGL+  AF Y++ +GG++SE+ YPY     +    +C +  K +V  DTGFV +P   E+AL +A+ T+GPIS+A  A  E F  YK GIY +  CS+  ++H VL+VGYG +  E     YW++KNSWG +WG  GY +  ++ +N C +A  + YP V
Sbjct:   10 FCLGIASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPY-----EATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
[Close]
BLAST of Cathepsin L vs. Ensembl Human
Match: CTSH (cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535])

HSP 1 Score: 221.861 bits (564), Expect = 1.130e-68
Identity = 134/316 (42.41%), Postives = 176/316 (55.70%), Query Frame = 3 
Query:  288 FKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ---LNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGA-VTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNV--RINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPL 1211
            FKS  +K +  Y     S E+ + R   F  +  +IN HN     G+  F+M +N  SD +  E       +  +  + T S YL     P  P S DWR KG  V+ VKNQ  CGSC+ FSTTGALE  +   TG ++SL+EQQ+VDC  D  ++GC GGL   AF YI Y+ GI  E  YPY     +  +  C F+  KA+G       +   DEEA+ EA+    P+S AF  T+ F  Y+ GIY    C     ++NHAVL VGYG  E++G PYWI+KNSWGP+WG NGYF  ER KNMC +A  + YP+
Sbjct:   23 FKSWMSKHRKTY-----STEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYL-RGTGP-YPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY-----QGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG--EKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPI 320
[Close]
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 262.307 bits (669), Expect = 1.242e-84
Identity = 145/334 (43.41%), Postives = 201/334 (60.18%), Query Frame = 3 
Query:  246 NTKFSRKISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLK-------ISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            + K SR+I S +     ++  +K  + K Y   E E      F+ + + I NHN+    G K F+M +NH++D    ++ +LN  +       I N + S   P N++  +P+  DWRD   VT+VKNQ  CGSC+AFS TGALEGQ  RK G L+SLSEQ +VDC   + ++GC+GGL+  AF YI+ + G+++E+ YPY     K  +  C+F +K     D G+V  P GDEE L+ A+ T GPISIA  A  R F+ YK G+Y+D+ CS+  ++H VLLVGYG D E G  YWI+KNSWG  WGE GY R  RN+ N C +A  + YPLV
Sbjct:   18 SAKLSRQIESAI----EKWDDYKEDFDKEYSESE-EQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKN-SSSFLAPFNVQ--VPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPY-----KGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337
[Close]
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 205.682 bits (522), Expect = 1.385e-64
Identity = 105/203 (51.72%), Postives = 136/203 (67.00%), Query Frame = 3 
Query:  618 CGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            CGSC+AFS TGALEGQ  RK G L+SLSEQ +VDC   + ++GC+GGL+  AF YI+ + G+++E+ YPY     K  +  C+F +K     D G+V  P GDEE L+ A+ T GPISIA  A  R F+ YK G+Y+D+ CS+  ++H VLLVGYG D E G  YWI+KNSWG  WGE GY R  RN+ N C +A  + YPLV
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPY-----KGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198
[Close]
BLAST of Cathepsin L vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 205.682 bits (522), Expect = 1.385e-64
Identity = 105/203 (51.72%), Postives = 136/203 (67.00%), Query Frame = 3 
Query:  618 CGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            CGSC+AFS TGALEGQ  RK G L+SLSEQ +VDC   + ++GC+GGL+  AF YI+ + G+++E+ YPY     K  +  C+F +K     D G+V  P GDEE L+ A+ T GPISIA  A  R F+ YK G+Y+D+ CS+  ++H VLLVGYG D E G  YWI+KNSWG  WGE GY R  RN+ N C +A  + YPLV
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPY-----KGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198
[Close]
BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 201.06 bits (510), Expect = 1.988e-59
Identity = 107/222 (48.20%), Postives = 137/222 (61.71%), Query Frame = 3 
Query:  555 LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYH--DDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            LPESFDWR+KGAVT+VKNQ  CGSC+AFSTTG +EG  F     L+SLSEQ++VDCD +D GC+GGL  +A+  I   GG+E E  YPY           C+   K       G V+L P DE  +++ LVT GPISI  +A    + Y++G+ H    +C    +NH VL+VGYG D     PYWI+KNSWGP WGE GYF+  R KN+C +   +   LV
Sbjct:  264 LPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPY-----DGRGETCHLVRKDIAVYINGSVEL-PHDEVEMQKWLVTKGPISIGLNANT-LQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKD--GRKPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALV 476
[Close]
BLAST of Cathepsin L vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 201.06 bits (510), Expect = 1.988e-59
Identity = 107/222 (48.20%), Postives = 137/222 (61.71%), Query Frame = 3 
Query:  555 LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYH--DDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            LPESFDWR+KGAVT+VKNQ  CGSC+AFSTTG +EG  F     L+SLSEQ++VDCD +D GC+GGL  +A+  I   GG+E E  YPY           C+   K       G V+L P DE  +++ LVT GPISI  +A    + Y++G+ H    +C    +NH VL+VGYG D     PYWI+KNSWGP WGE GYF+  R KN+C +   +   LV
Sbjct:  264 LPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPY-----DGRGETCHLVRKDIAVYINGSVEL-PHDEVEMQKWLVTKGPISIGLNANT-LQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKD--GRKPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALV 476
[Close]
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 260.766 bits (665), Expect = 6.515e-84
Identity = 139/322 (43.17%), Postives = 203/322 (63.04%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---------NSLKISN--LTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            E+  FKL++ K Y+   +E  R   F  ++ +I  HNQ F +G   F++ +N  +D    EF QL           L+ ++    G T++ P ++   LP+S DWR KGAVT VK+Q +CGSC+AFS+TGALEGQ FRK+G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TD GF  +P GDE+ + EA+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VG+G D ESG  YW++KNSWG  WG+ G+ +  RNK N C +A  S YPLV
Sbjct:   28 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT--LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD-ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
[Close]
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 261.151 bits (666), Expect = 1.009e-83
Identity = 139/322 (43.17%), Postives = 203/322 (63.04%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---------NSLKISN--LTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            E+  FKL++ K Y+   +E  R   F  ++ +I  HNQ F +G   F++ +N  +D    EF QL           L+ ++    G T++ P ++   LP+S DWR KGAVT VK+Q +CGSC+AFS+TGALEGQ FRK+G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TD GF  +P GDE+ + EA+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VG+G D ESG  YW++KNSWG  WG+ G+ +  RNK N C +A  S YPLV
Sbjct:   58 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT--LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD-ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371
[Close]
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 255.758 bits (652), Expect = 4.697e-82
Identity = 136/319 (42.63%), Postives = 200/319 (62.70%), Query Frame = 3 
Query:  306 KFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---------NSLKISN--LTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +  L++ K Y+   +E  R   F  ++ +I  HNQ F +G   F++ +N  +D    EF QL           L+ ++    G T++ P ++   LP+S DWR KGAVT VK+Q +CGSC+AFS+TGALEGQ FRK+G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TD GF  +P GDE+ + EA+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VG+G D ESG  YW++KNSWG  WG+ G+ +  RNK N C +A  S YPLV
Sbjct:   28 RLVLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT--LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD-ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338
[Close]
BLAST of Cathepsin L vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 233.417 bits (594), Expect = 1.374e-74
Identity = 113/224 (50.45%), Postives = 157/224 (70.09%), Query Frame = 3 
Query:  555 LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            LP+S DWR KGAVT VK+Q +CGSC+AFS+TGALEGQ FRK+G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TD GF  +P GDE+ + EA+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VG+G D ESG  YW++KNSWG  WG+ G+ +  RNK N C +A  S YPLV
Sbjct:   32 LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD-ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249
[Close]
BLAST of Cathepsin L vs. Ensembl Fly
Match: CG4847 (gene:FBgn0034229 transcript:FBtr0086934)

HSP 1 Score: 229.18 bits (583), Expect = 5.101e-71
Identity = 128/317 (40.38%), Postives = 173/317 (54.57%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEF-NQLNSLKIS---NLTGSTYLPLNIKPG--LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD----YGCSGGLVPDAFNYI-KYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            +F  F  Q GK Y S          F  ++  +   N  F +G   F+  +N  +D T  EF +QL  LK S       +  L L   P   +P++FDWR+ G VT VK Q  CGSC+AF+TTGA+EG  FRKTG+L +LSEQ +VDC  V+     GC GG    AF +I +   G+  E  YPY+          C +   K+  T  GF  +PP DEE L++ + T+GP++ + +  E  K+Y  GIY+DD C+    NH++L+VGYG   E G  YWI+KNSW   WGE GYFR  R KN C +A    YP+V
Sbjct:   81 DFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDN-----KGTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYG--SEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEECSYPVV 390
[Close]
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 265.774 bits (678), Expect = 8.315e-86
Identity = 139/317 (43.85%), Postives = 198/317 (62.46%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---NSLKISNLT----GSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KL++GK Y S E+E+ R   ++ ++  +  HN M ++G K +++ + + +D + EE+ QL     L   N T    GST+  L     +P++ DWRDKG VT++K+QK CGSC+AFS TG+LEGQ FRKTG L+SLSEQQ+VDC   + +YGC GGL+  AF YI+ + G+++E  YPY     +  +  C F       + TG+V +  GDE AL+EA+ TIGPIS+A  A    F+ Y +G+Y++  CS+  ++H VL VGYG    +G  YWI+KNSWG  WG  GY    RNK N C +A  + YPLV
Sbjct:   25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPY-----EAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYG--SSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 265.774 bits (678), Expect = 8.315e-86
Identity = 139/317 (43.85%), Postives = 198/317 (62.46%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---NSLKISNLT----GSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KL++GK Y S E+E+ R   ++ ++  +  HN M ++G K +++ + + +D + EE+ QL     L   N T    GST+  L     +P++ DWRDKG VT++K+QK CGSC+AFS TG+LEGQ FRKTG L+SLSEQQ+VDC   + +YGC GGL+  AF YI+ + G+++E  YPY     +  +  C F       + TG+V +  GDE AL+EA+ TIGPIS+A  A    F+ Y +G+Y++  CS+  ++H VL VGYG    +G  YWI+KNSWG  WG  GY    RNK N C +A  + YPLV
Sbjct:   25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPY-----EAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYG--SSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 265.774 bits (678), Expect = 8.315e-86
Identity = 139/317 (43.85%), Postives = 198/317 (62.46%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---NSLKISNLT----GSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KL++GK Y S E+E+ R   ++ ++  +  HN M ++G K +++ + + +D + EE+ QL     L   N T    GST+  L     +P++ DWRDKG VT++K+QK CGSC+AFS TG+LEGQ FRKTG L+SLSEQQ+VDC   + +YGC GGL+  AF YI+ + G+++E  YPY     +  +  C F       + TG+V +  GDE AL+EA+ TIGPIS+A  A    F+ Y +G+Y++  CS+  ++H VL VGYG    +G  YWI+KNSWG  WG  GY    RNK N C +A  + YPLV
Sbjct:   25 EFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPY-----EAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYG--SSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: si:dkey-269i1.4 (si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-37])

HSP 1 Score: 243.817 bits (621), Expect = 2.394e-77
Identity = 133/325 (40.92%), Postives = 198/325 (60.92%), Query Frame = 3 
Query:  270 SSLMVDFKSEFAKFKLQYGKVY-ESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGL---PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            SS+ +     +  +K Q+GK Y E +E          L ++E   HN  +  G+  F+M +N   D T EEF    +    +   ++  PL ++P     P+  DWR +G VT VK+QK CGSC++FS+TGALEGQLFRKTG LIS+SEQ +VDC   H + GC+GGL+  AF Y+K + G++SEQ YPY++    + +  C +  +  V   TGFV +P G+E AL  A+  +GP+S+A  A+ +  + Y++GIY++  CS+ R++HAVL+VGYG    + +G  YWI+KNSW  KWG+ GY    ++K N C +A  + YPL+
Sbjct:   18 SSIDIQLDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIE--QHNFEYSYGNHTFKMGMNQFGDMTNEEFRHAMNGYKHDPNQTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLA----RDDLPCRYDPRFNVAKITGFVDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYPLM 336
[Close]
BLAST of Cathepsin L vs. Ensembl Zebrafish
Match: si:dkey-239j18.3 (si:dkey-239j18.3 [Source:ZFIN;Acc:ZDB-GENE-121214-39])

HSP 1 Score: 243.817 bits (621), Expect = 3.002e-77
Identity = 133/325 (40.92%), Postives = 198/325 (60.92%), Query Frame = 3 
Query:  270 SSLMVDFKSEFAKFKLQYGKVY-ESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGL---PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            SS+ +     +  +K Q+GK Y E +E          L ++E   HN  +  G+  F+M +N   D T EEF Q  +    +   ++  PL ++P     P+  DWR +G VT VK+QK CGSC++FS+TGALEGQLFRKTG LIS+SEQ +VDC     + GC+GGL+  AF Y+K + G++SEQ YPY++    + +  C +  +  V   TGFV +P G+E AL  A+  +GP+S+A  A+ +  + Y++GIY++  CS+ R++HAVL+VGYG    + +G  YWI+KNSW  KWG+ GY    ++K N C +A  + YPL+
Sbjct:   18 SSIDIQLDDHWNSWKSQHGKSYHEDVEVGRRMIWEENLRKIE--QHNFEYSYGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNQTSQGPLFMEPSFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPQGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLA----RDDLPCRYDPRFNVAKITGFVDIPSGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACSSSRLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGVATKASYPLM 336
[Close]
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 231.491 bits (589), Expect = 1.795e-72
Identity = 126/315 (40.00%), Postives = 189/315 (60.00%), Query Frame = 3 
Query:  285 DFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKI--SNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            +  S++  +K  Y + Y     E  R   +  +   I+ HN+ F +G   + + +NH+ D T EE  Q +  LK+  ++   +TY+P      +PE  D+R KG VT V NQ  CGSC+AFS+ GALEGQL +KTG L+SLS Q +VDCD  +YGC GG + +AF Y++ +GGI+S+ EYPYV       +  C++       T  G+ ++P G E+AL+ A+  +GP+S++  A+   F+ YK G+Y+D  C+   +NHAVL+VGYG   E G  +WIIKNSWG  WG+ GY    R+ KN C +A  + +P++
Sbjct:   23 NLDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYIP-EWNSRIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVG-----QDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYG--NEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFPVM 329
[Close]
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 231.491 bits (589), Expect = 2.140e-72
Identity = 126/315 (40.00%), Postives = 189/315 (60.00%), Query Frame = 3 
Query:  285 DFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKI--SNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            +  S++  +K  Y + Y     E  R   +  +   I+ HN+ F +G   + + +NH+ D T EE  Q +  LK+  ++   +TY+P      +PE  D+R KG VT V NQ  CGSC+AFS+ GALEGQL +KTG L+SLS Q +VDCD  +YGC GG + +AF Y++ +GGI+S+ EYPYV       +  C++       T  G+ ++P G E+AL+ A+  +GP+S++  A+   F+ YK G+Y+D  C+   +NHAVL+VGYG   E G  +WIIKNSWG  WG+ GY    R+ KN C +A  + +P++
Sbjct:   30 NLDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYIP-EWNSRIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDTDNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVG-----QDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYG--NEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFPVM 336
[Close]
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 229.95 bits (585), Expect = 8.669e-72
Identity = 129/283 (45.58%), Postives = 174/283 (61.48%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLK-ISNLTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGM--DEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I  HN     G     + +N   D T EEF QL N  K    + GST+L P N +   P+S DWR KG VT VK+Q  CGSC+AFSTTGALEGQ +R TG +ISLSEQ +VDC     + GC+GGL+  AF Y+K +GGI+SE  YPY    T K +  C++        DTGFV +  G E+ L  A+ ++GP+S+A  A  + F+ YK+GIY++  CS+  ++H VL+VGYG   ++E G  YWI+KNSW  KWG +GY    +++ N C +A  + YPLV
Sbjct:   59 IEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPNNFES--PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPY----TAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335
[Close]
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 230.335 bits (586), Expect = 9.263e-72
Identity = 129/283 (45.58%), Postives = 174/283 (61.48%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLK-ISNLTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGM--DEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I  HN     G     + +N   D T EEF QL N  K    + GST+L P N +   P+S DWR KG VT VK+Q  CGSC+AFSTTGALEGQ +R TG +ISLSEQ +VDC     + GC+GGL+  AF Y+K +GGI+SE  YPY    T K +  C++        DTGFV +  G E+ L  A+ ++GP+S+A  A  + F+ YK+GIY++  CS+  ++H VL+VGYG   ++E G  YWI+KNSW  KWG +GY    +++ N C +A  + YPLV
Sbjct:   66 IEFHNLEHSLGKHSHSLGMNQFGDMTNEEFRQLMNGYKNQKKIRGSTFLAPNNFES--PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPY----TAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342
[Close]
BLAST of Cathepsin L vs. Ensembl Xenopus
Match: harbi1 (harbinger transposase derived 1 [Source:Xenbase;Acc:XB-GENE-6077433])

HSP 1 Score: 211.846 bits (538), Expect = 8.537e-65
Identity = 126/317 (39.75%), Postives = 176/317 (55.52%), Query Frame = 3 
Query:  288 FKSEFAKFKLQYGKVYESIEKENERFNNFILSQVE--INNHNQMFEKGHKKFQMEINHMSDWTPEEF-NQLNSLKISNLTGSTYLPLN---IKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSA-TERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
              SE+  +K  Y K Y++  K +E     I  +    I +HN  F +G   +++ +N   D T EE    +  LK+    G T L  +       +P S D+R KG VT +++Q  CGSC+AFST GALEGQL +KTG L+ +S Q +VDC   ++GC GG +  AF Y+K + GI+SE+ YPYV G+ +K    C +          GF ++  G E AL++A+  +GPIS+   A  + F  YK GIY+D  C    INHAVL VGYG  ++    YWIIKNSWG  WG  GY    R K N C +A  + YP++
Sbjct:   24 LDSEWEIWKTTYHKHYDN--KIHELMRRLIWEKNLNIIRSHNLEFTQGLHTYELGMNKFGDMTSEEVVRMMTGLKVHTGMGPTNLTSDEDEASQRIPNSIDYRKKGYVTPIRDQGECGSCWAFSTVGALEGQLMKKTGKLVGISPQNLVDCVKDNFGCGGGYMTTAFKYVKKNKGIDSEEAYPYV-GMDQK----CKYNVSGRAAEIKGFKEVKKGSETALKKAVGLVGPISVGIDAGLDTFFLYKKGIYYDKSCDGDSINHAVLAVGYGKQKKG--KYWIIKNSWGEDWGNKGYILMAREKGNACGIANLASYPVM 331
[Close]
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 238.039 bits (606), Expect = 5.825e-75
Identity = 134/321 (41.74%), Postives = 197/321 (61.37%), Query Frame = 3 
Query:  288 FKSEFAKFKLQYGKVYESIEKENERF---NNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLKISNLTGSTYL--PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            F +E+ ++K  + ++Y + E+E  R     N  + Q+    HN  +  G   F ME+N   D T EEF Q+ N  +            PL +K  +P+S DWR+KG VT VKNQ  CGSC+AFS +G LEGQ+F KTG LISLSEQ +VDC H   + GC+GGL+  AF YIK +GG++SE+ YPY     +  + +C ++ + AV  DTGFV +P   E+AL +A+ T+GPIS+A  A+    + Y +GIY++  CS+  ++H VLLVGYG +  + +   YW++KNSWG +WG  GY +  +++ N C +A  + YP+V
Sbjct:   25 FSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQL----HNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLK--IPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPY-----EAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
[Close]
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 238.039 bits (606), Expect = 5.825e-75
Identity = 134/321 (41.74%), Postives = 197/321 (61.37%), Query Frame = 3 
Query:  288 FKSEFAKFKLQYGKVYESIEKENERF---NNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-NSLKISNLTGSTYL--PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            F +E+ ++K  + ++Y + E+E  R     N  + Q+    HN  +  G   F ME+N   D T EEF Q+ N  +            PL +K  +P+S DWR+KG VT VKNQ  CGSC+AFS +G LEGQ+F KTG LISLSEQ +VDC H   + GC+GGL+  AF YIK +GG++SE+ YPY     +  + +C ++ + AV  DTGFV +P   E+AL +A+ T+GPIS+A  A+    + Y +GIY++  CS+  ++H VLLVGYG +  + +   YW++KNSWG +WG  GY +  +++ N C +A  + YP+V
Sbjct:   25 FSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQL----HNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGRLFQEPLMLK--IPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPY-----EAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
[Close]
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsh (cathepsin H [Source:MGI Symbol;Acc:MGI:107285])

HSP 1 Score: 221.861 bits (564), Expect = 8.572e-69
Identity = 133/315 (42.22%), Postives = 175/315 (55.56%), Query Frame = 3 
Query:  291 KSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ---LNSLKISNLTGSTYLPLNIKPGLPESFDWRDKG-AVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNV--RINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPL 1211
            K  F  +  Q+ K Y S+E  N R   F  +  +I  HNQ   + H  F+M +N  SD +  E       +  +  + T S YL     P  P S DWR KG  V+ VKNQ  CGSC+ FSTTGALE  +   +G ++SL+EQQ+VDC     ++GC GGL   AF YI Y+ GI  E  YPY+       + +C F  +KAV      V +   DE A+ EA+    P+S AF  TE F  YK+G+Y    C     ++NHAVL VGYG  E++G  YWI+KNSWG +WGENGYF  ER KNMC +A  + YP+
Sbjct:   30 KFHFKSWMKQHQKTYSSVEY-NHRLQMFANNWRKIQAHNQ---RNHT-FKMALNQFSDMSFAEIKHKFLWSEPQNCSATKSNYLR-GTGP-YPSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMLSLAEQQLVDCAQAFNNHGCKGGLPSQAFEYILYNKGIMEEDSYPYIG-----KDSSCRFNPQKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFLMYKSGVYSSKSCHKTPDKVNHAVLAVGYG--EQNGLLYWIVKNSWGSQWGENGYFLIERGKNMCGLAACASYPI 330
[Close]
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsk (cathepsin K [Source:MGI Symbol;Acc:MGI:107823])

HSP 1 Score: 218.394 bits (555), Expect = 1.902e-67
Identity = 125/317 (39.43%), Postives = 183/317 (57.73%), Query Frame = 3 
Query:  279 MVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKI----SNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYP 1208
            M+D + E   +K  + K Y S   E  R   +  +  +I+ HN     G   +++ +NH+ D T EE  Q +  L+I    S    + Y P   +  +P+S D+R KG VT VKNQ  CGSC+AFS+ GALEGQL +KTG L++LS Q +VDC   +YGC GG +  AF Y++ +GGI+SE  YPYV       + +C +          G+ ++P G+E+AL+ A+  +GPIS++  A+   F+ Y  G+Y+D+ C    +NHAVL+VGYG   + G+ +WIIKNSWG  WG  GY    RNK N C +   + +P
Sbjct:   21 MLDTQWEL--WKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTP-EWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVG-----QDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGT--QKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFP 327
[Close]
BLAST of Cathepsin L vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452])

HSP 1 Score: 216.853 bits (551), Expect = 7.691e-67
Identity = 119/284 (41.90%), Postives = 173/284 (60.92%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGS-TYLPLNI--KPGL---PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I+ HN+ + KG   F +E+N   D T  EF +L    ++   G  T + + +  +P L   P+S DWRD G VT VK+Q  CGSC+AFS  G+LEGQ+FRKTG L+ LS Q +VDC     + GC GGL   AF Y+K +GG+++   YPY     +  N  C +  K +  T TGFV +    E+AL +A+ T+GPIS+      + F+ YK G+Y++  CS+  ++HAVL+VGYG +E  G  YW++KNSWG  WG NGY +  +++ N C +A ++ YP+V
Sbjct:   59 IDLHNEDYLKGKHGFSLEMNAFGDLTNTEFREL----MTGFQGQKTKMMMKVFQEPLLGDVPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCDGGLPDLAFQYVKDNGGLDTSVSYPY-----EALNGTCRYNPKNSAATVTGFVNV-QSSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYG-EESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331
[Close]
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q26636|CATL_SARPE (Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 SV=1)

HSP 1 Score: 265.003 bits (676), Expect = 1.433e-84
Identity = 144/333 (43.24%), Postives = 211/333 (63.36%), Query Frame = 3 
Query:  258 SRKISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ--------LNSL--KISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            ++ IS L +  K E+  +KLQ+ K Y +  +E  R   F  ++ +I  HNQ+F +G   +++ +N  +D    EF +        L  L  + + L G+TY+P      +P+S DWR+ GAVT VK+Q +CGSC+AFS+TGALEGQ FRK G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TDTGFV +P GDEE +++A+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VGYG D ESG  YW++KNSWG  WGE GY +  RN+ N C +A  S YP V
Sbjct:   15 TQAISPLDL-IKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQLFAQGKVSYKLGLNKYADMLHHEFKETMNGYNHTLRQLMRERTGLVGATYIP-PAHVTVPKSVDWREHGAVTGVKDQGHCGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EGIDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTD-ESGMDYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
[Close]
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|O45734|CPL1_CAEEL (Cathepsin L-like OS=Caenorhabditis elegans OX=6239 GN=cpl-1 PE=1 SV=1)

HSP 1 Score: 262.307 bits (669), Expect = 1.580e-83
Identity = 145/334 (43.41%), Postives = 201/334 (60.18%), Query Frame = 3 
Query:  246 NTKFSRKISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLK-------ISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            + K SR+I S +     ++  +K  + K Y   E E      F+ + + I NHN+    G K F+M +NH++D    ++ +LN  +       I N + S   P N++  +P+  DWRD   VT+VKNQ  CGSC+AFS TGALEGQ  RK G L+SLSEQ +VDC   + ++GC+GGL+  AF YI+ + G+++E+ YPY     K  +  C+F +K     D G+V  P GDEE L+ A+ T GPISIA  A  R F+ YK G+Y+D+ CS+  ++H VLLVGYG D E G  YWI+KNSWG  WGE GY R  RN+ N C +A  + YPLV
Sbjct:   18 SAKLSRQIESAI----EKWDDYKEDFDKEYSESE-EQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKN-SSSFLAPFNVQ--VPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPY-----KGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHG-DYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337
[Close]
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q95029|CATL_DROME (Cathepsin L OS=Drosophila melanogaster OX=7227 GN=Cp1 PE=2 SV=2)

HSP 1 Score: 261.151 bits (666), Expect = 1.012e-82
Identity = 139/322 (43.17%), Postives = 203/322 (63.04%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL---------NSLKISN--LTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            E+  FKL++ K Y+   +E  R   F  ++ +I  HNQ F +G   F++ +N  +D    EF QL           L+ ++    G T++ P ++   LP+S DWR KGAVT VK+Q +CGSC+AFS+TGALEGQ FRK+G L+SLSEQ +VDC   + + GC+GGL+ +AF YIK +GGI++E+ YPY     +  + +C+F +     TD GF  +P GDE+ + EA+ T+GP+S+A  A+ E F+ Y  G+Y++  C    ++H VL+VG+G D ESG  YW++KNSWG  WG+ G+ +  RNK N C +A  S YPLV
Sbjct:   58 EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVT--LPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPY-----EAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD-ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371
[Close]
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|P05167|ALEU_HORVU (Thiol protease aleurain OS=Hordeum vulgare OX=4513 PE=2 SV=1)

HSP 1 Score: 248.054 bits (632), Expect = 1.035e-77
Identity = 135/312 (43.27%), Postives = 189/312 (60.58%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEF--NQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNV--RINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
             FA+F ++YGK YES  +   RF  F  S  E+ + N+   KG   +++ IN  SD + EEF   +L + +  + T +    +     LPE+ DWR+ G V+ VKNQ +CGSC+ FSTTGALE    + TG  ISLSEQQ+VDC     ++GC+GGL   AF YIKY+GGI++E+ YPY     K  N  C++K + A       V +    E+ L+ A+  + P+S+AF   + F+ YK+G+Y  D C      +NHAVL VGYG+  E+G PYW+IKNSWG  WG+NGYF+ E  KNMC +A  + YP+V
Sbjct:   60 RFARFAVRYGKSYESAAEVRRRFRIFSESLEEVRSTNR---KG-LPYRLGINRFSDMSWEEFQATRLGAAQTCSATLAGNHLMRDAAALPETKDWREDGIVSPVKNQAHCGSCWTFSTTGALEAAYTQATGKNISLSEQQLVDCAGGFNNFGCNGGLPSQAFEYIKYNGGIDTEESYPY-----KGVNGVCHYKAENAAVQVLDSVNITLNAEDELKNAVGLVRPVSVAFQVIDGFRQYKSGVYTSDHCGTTPDDVNHAVLAVGYGV--ENGVPYWLIKNSWGADWGDNGYFKMEMGKNMCAIATCASYPVV 360
[Close]
BLAST of Cathepsin L vs. UniProt/SwissProt
Match: sp|Q28944|CATL1_PIG (Cathepsin L1 OS=Sus scrofa OX=9823 GN=CTSL PE=2 SV=1)

HSP 1 Score: 244.588 bits (623), Expect = 1.015e-76
Identity = 130/317 (41.01%), Postives = 199/317 (62.78%), Query Frame = 3 
Query:  285 DFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +  +++ K+K  +G++Y  + +E  R   +  +   I  HNQ + +G   F M +N   D T EEF Q +N  +            ++   +P+S DWR+KG VT VKNQ  CGSC+AFS TGALEGQ+FRKTG L+SLSEQ +VDC     + GC+GGL+ +AF Y+K +GG+++E+ YPY+     +   +C +K + +   DTGFV +P   E+AL +A+ T+GPIS+A  A    F+ YK+GIY+D  CS+  ++H VL+VGYG +  + + + +WI+KNSWGP+WG NGY +  +++ N C ++  + YP V
Sbjct:   24 NLDADWYKWKATHGRLY-GMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKSVDWREKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDTEESYPYLG----RETNSCTYKPECSAANDTGFVDIPQ-REKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
[Close]
BLAST of Cathepsin L vs. TrEMBL
Match: A0A183T8C8 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS12726 PE=3 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 1.558e-90
Identity = 154/294 (52.38%), Postives = 193/294 (65.65%), Query Frame = 3 
Query:  369 NFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEF------NQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNV--RINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            NF+ +  +I  HNQ+F+K    F+M IN  SD   EEF      N    LK  +L    YL   +   LPES DWR +G VT VKNQ  CGSC+AFSTTG++EGQL RK+G L+SLSEQQ+VDC  ++ + GC+GGL+ +AF YI+ +GGI+  ++YPYVSG T+  N  C F   KAV T TGFV +  G+EE LR AL   GPISIA  A ++ F  Y +GIY D  C N    +NHAVLLVGYG+  E G PYWI+KNSWGP WGE+GY R  RNK N+C +A  S +PLV
Sbjct:   70 NFVENVKKIWQHNQLFKKDESSFEMGINEFSDMNLEEFRTRLGYNASLRLKGGDLPHFRYLARQLDTPLPESHDWRSQGLVTPVKNQGRCGSCWAFSTTGSIEGQLKRKSGQLVSLSEQQLVDCSTNYNNLGCNGGLMDNAFEYIQDAGGIQRSEDYPYVSGETESQNDQCGFDRSKAVATVTGFVDVDSGNEEELRRALYFHGPISIAIDAGQQSFMSYHSGIYDDPRCQNAPSELNHAVLLVGYGV--EKGVPYWIVKNSWGPNWGESGYIRMRRNKNNLCGVATASSFPLV 361
[Close]
BLAST of Cathepsin L vs. TrEMBL
Match: A0A0X3NKX4 (Cathepsin L OS=Schistocephalus solidus OX=70667 GN=CATL PE=3 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 3.826e-90
Identity = 154/294 (52.38%), Postives = 193/294 (65.65%), Query Frame = 3 
Query:  369 NFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEF------NQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNV--RINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            NF+ +  +I  HNQ+F+K    F+M IN  SD   EEF      N    LK  +L    YL   +   LPES DWR +G VT VKNQ  CGSC+AFSTTG++EGQL RK+G L+SLSEQQ+VDC  ++ + GC+GGL+ +AF YI+ +GGI+  ++YPYVSG T+  N  C F   KAV T TGFV +  G+EE LR AL   GPISIA  A ++ F  Y +GIY D  C N    +NHAVLLVGYG+  E G PYWI+KNSWGP WGE+GY R  RNK N+C +A  S +PLV
Sbjct:  101 NFVENVKKIWQHNQLFKKDESSFEMGINEFSDMNLEEFRTRLGYNASLRLKGGDLPHFRYLARQLDTPLPESHDWRSQGLVTPVKNQGRCGSCWAFSTTGSIEGQLKRKSGQLVSLSEQQLVDCSTNYNNLGCNGGLMDNAFEYIQDAGGIQRSEDYPYVSGETESQNDQCGFDRSKAVATVTGFVDVDSGNEEELRRALYFHGPISIAIDAGQQSFMSYHSGIYDDPRCQNAPSELNHAVLLVGYGV--EKGVPYWIVKNSWGPNWGESGYIRMRRNKNNLCGVATASSFPLV 392
[Close]
BLAST of Cathepsin L vs. TrEMBL
Match: A0A0N5CEB4 (Uncharacterized protein OS=Strongyloides papillosus OX=174720 PE=3 SV=1)

HSP 1 Score: 281.182 bits (718), Expect = 1.113e-87
Identity = 159/358 (44.41%), Postives = 218/358 (60.89%), Query Frame = 3 
Query:  186 ANAEIWEPDRNLSNVHQSHANTKFSRK--ISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKI--SNLTGST-------YLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            ++ E+ +  + +   H    N    RK  + S+M     ++  FK  + K Y   + ENER   F+ +Q  +  HN+ F  G   F++E+NH++D   EE+++LN  K+    L G+T         PLN++  +P+SFDWR+KG VTEVKNQ+ CGSCY+FS TGALEGQ  R TG+L+SLSEQ IVDC   + + GC+GGL+   F YIK + G+++E+ YPY     K     C+FK++    TD G+V LP GDE+AL+ AL T GPIS+A  A    F+ YK GIY++  CS   ++H VLLVGYG   E G  YWI+KNSWG  WGE GY R  RNK N C +A  + YPLV
Sbjct:   51 SSEEVDQVAKAIKAGHPDRENKYSDRKSSLESMMKQGLEDWELFKQLHNKKYAHEKIENERMFTFLTNQQRVREHNKRFLNGEVSFEIEMNHLADLPFEEYSKLNGFKMPKEGLLGATKSNASQWLPPLNVQ--VPDSFDWREKGYVTEVKNQQACGSCYSFSATGALEGQHKRVTGDLVSLSEQNIVDCSTSYGNNGCNGGLMDYVFEYIKQNKGVDTEESYPY-----KGKEGKCHFKKRDIGATDIGYVDLPEGDEDALKVALATQGPISVAIDAGHISFQMYKKGIYYEPKCSPENLDHGVLLVGYGTCPEHGD-YWIVKNSWGTTWGEKGYIRMARNKNNHCGIATKASYPLV 400
[Close]
BLAST of Cathepsin L vs. TrEMBL
Match: R4WD68 (Cathepsin L OS=Riptortus pedestris OX=329032 PE=2 SV=1)

HSP 1 Score: 278.485 bits (711), Expect = 2.087e-87
Identity = 147/317 (46.37%), Postives = 209/317 (65.93%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEF----NQLN-SLKISN--LTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF+ FKL + K Y S  +E  R   F+ ++  +  HN  FE+G   F++++NHM+D    EF    N  N SLK +N  + GST++P      LP + DWR KGAVT VKNQ  CGSC+AFS+TGALEGQ FRKT  LISLSEQ +VDC   + + GC GGL+ +AF Y+K + GI++E+ YPY     +  +  C F+ +    TDTGF+ +P GDEEAL++A+ T+GP+S+A  A+   F+ Y +G+Y++  CS+  ++H VL+VGYG  +E G  YW++KNSWG +WGE+GY +  RN+ N C +A ++ YPLV
Sbjct:   26 EFSLFKLAHNKQYASDVEEKYRKKIFVENKKIVAKHNSRFEQGLVSFKLKLNHMADMLVHEFAATYNGFNKSLKATNEKIVGSTFIPPE-HVTLPSNVDWRKKGAVTPVKNQGQCGSCWAFSSTGALEGQHFRKTNKLISLSEQNLVDCSQKYGNNGCEGGLMDNAFQYVKENHGIDTEKSYPY-----EGEDEQCRFQRRSIGATDTGFMDIPQGDEEALQKAVATVGPVSVAIDASHSSFQLYSSGVYYEPECSSEELDHGVLVVGYGTTDE-GEDYWLVKNSWGTRWGEDGYIKMARNRDNNCGIASSASYPLV 335
[Close]
BLAST of Cathepsin L vs. TrEMBL
Match: B3SVE2 (Cathepsin L-like protease OS=Strongylus vulgaris OX=40348 GN=cpl PE=3 SV=1)

HSP 1 Score: 278.87 bits (712), Expect = 2.626e-87
Identity = 154/340 (45.29%), Postives = 208/340 (61.18%), Query Frame = 3 
Query:  240 HANTKFSRKISSLMVDFKSEFA---KFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGST--------YLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            H +T    ++ SL       F     +K  +GK Y   E EN+    F+ + + I+ HNQ    G K F+M +N ++D    ++ +LN  +     G +          P N++  +P+S DWRDKG VT+VKNQ  CGSC+AFS TGALEGQ  R +G ++SLSEQ +VDC   + ++GC+GGL+  AF YIK + GI++E+ YPYV   TK     C+FK+K     D GFV LP GDEEAL+ A+ T GPISIA  A  R F+ YK G+Y+D+ CS+  ++H VLLVGYG D E+G  YW+IKNSWGP WGE GY R  RN+ N C +A  + YPLV
Sbjct:   24 HDHTIRLHRVKSLRQKIDEAFKLWDDYKESFGKSYNKDE-ENDYMEAFVKNVIHIDEHNQEHRLGRKTFEMGLNSIADLPFSQYRKLNGYRHRRNFGDSMQSNGTKWLAPFNVE--IPDSVDWRDKGLVTDVKNQGMCGSCWAFSATGALEGQHARASGKMVSLSEQNLVDCSTKYGNHGCNGGLMDLAFEYIKDNHGIDTEESYPYVGRETK-----CHFKKKDIGAEDKGFVDLPEGDEEALKVAVATQGPISIAIDAGHRTFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEAG-DYWLIKNSWGPGWGEKGYIRIARNRSNHCGVATKASYPLV 354
[Close]
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607])

HSP 1 Score: 271.552 bits (693), Expect = 3.612e-88
Identity = 137/316 (43.35%), Postives = 207/316 (65.51%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNL------TGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KL++GK+Y S+E+E++R   ++ ++  +  HN + ++G K +++ +   +D   +E+ +L +  + +       + +T+L   ++  LP++ DWR KG VT++K+QK CGSC+AFS TG+LEGQ FRKTG L+SLSEQQ+VDC  D+ ++GC GGL+  AF YIK + GI++E  YPY     +  + +C FK      T TGFV +  GDE+AL+EA+ TIGPIS+A  A    F+ Y++GIY++  CS+  ++H VL VGYG D  +G  YW++KNSWG  WG  GY +  RN+ N C +A  S YPLV
Sbjct:   25 EFHAWKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPY-----EAVDGDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGTD--NGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333
[Close]
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000001970.2 (cathepsin L1-like [Source:NCBI gene;Acc:103022163])

HSP 1 Score: 267.7 bits (683), Expect = 1.224e-86
Identity = 142/316 (44.94%), Postives = 201/316 (63.61%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKI------SNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KLQ+GK Y S E+E++R   ++ ++  +  HN + ++G K +++ +N  +D   +EF  + S  +       +L  ST+L  +    LP+  DWR KG VT VKNQ  CGSC+AFS TGALEGQ+FRKTG LISLSEQQ+VDC     + GC+GG    +F+YIK S G+E++  YPY     K     C F  ++ + T +GF  LP GDE AL+ A+ +IGPIS+    ++  F+ YK+G+Y +  CS+ ++NHAVLLVGY  D  +G PYW++KNSWG  WG+NGY +  RNK N C +A  + YPLV
Sbjct:   25 EFNSWKLQHGKSYGSEEEESQRKMIWLTNRKLVLKHNMLADQGLKSYRLGMNIFADMKNQEFQAMFSHCVKSFDETDSLCTSTFLSEDEDAPLPQRVDWRAKGYVTFVKNQGICGSCWAFSATGALEGQMFRKTGKLISLSEQQLVDCSQSFGNLGCNGGWPSKSFDYIKSSKGLEADFTYPY-----KARKEICRFNPQRVIATCSGFKSLPKGDENALKNAVASIGPISVLIDTSKHTFQLYKSGVYDEPGCSSTKLNHAVLLVGYDND-PTGKPYWLVKNSWGINWGDNGYIKMSRNKMNQCGIATIATYPLV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000040914.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:116984:135874:-1 gene:ENSAMXG00000037672.1 transcript:ENSAMXT00000040914.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 263.462 bits (672), Expect = 4.135e-85
Identity = 136/313 (43.45%), Postives = 196/313 (62.62%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL-----NSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF ++KL++GK Y  +E+E++R  N++ ++  +  HN + ++G K +++ +NH +D   +E+ Q+     N  K  N T            LP++ DWR +G VT VK Q  CGSC+AFS TGALEGQ+FRKTG L+SLSEQQ+VDC   ++GC GG +  AF+Y+  + G+++E  YPY     +     C F  K    T TG+     GDE+AL+EA+ TIGPIS+   A +  F+ Y +G+Y++  CS+ +  HAVL+VGYG   E+G  YW++KNSWG  WGENGY +  RNK N C +A   YYPLV
Sbjct:   23 EFQEWKLKFGKKYHLMEEESQRKMNWMTNRKLVLEHNMLADQGLKTYRLGMNHFADMDNQEYRQMLKGFFNRNKAHNATTLLQKTEGSAAALPDTVDWRTRGYVTGVKTQGICGSCWAFSVTGALEGQMFRKTGRLVSLSEQQLVDCTTRNFGCDGGYLDRAFDYVMKNRGLDTEASYPY-----EDRQWKCRFNPKTVGATCTGYRSTRSGDEKALQEAVATIGPISVVIDAGQVSFQQYTSGVYNEPHCSSGKY-HAVLVVGYGT--ENGQDYWLVKNSWGTLWGENGYIKMSRNKYNQCGIATEPYYPLV 327
[Close]
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ENSAMXT00000034892.1 (cathepsin L1-like [Source:NCBI gene;Acc:107196839])

HSP 1 Score: 262.692 bits (670), Expect = 1.232e-84
Identity = 140/316 (44.30%), Postives = 200/316 (63.29%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKI------SNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +KLQ+GK Y+S E+E++R   ++ ++  +  HN + ++G K +++ +N   D   +EF  + S  +       +L  ST+L       LP   DWR KG VT+VK+Q  CGSC+AFS TGALEGQ+FRKTG LISLSE+Q+VDC     + GC+GG    +F YIK + G+E++  YPY     K     C F  ++ V T +GF  LP GDE AL++A+  IGPIS+A   ++  F+ YK+G+Y +  CS+ R+NHAV+LVGYG +   G  YW++KNSWG  WG+NGY +  RNK N C +A ++ YPLV
Sbjct:   26 EFNSWKLQHGKSYDSEEEESQRKMIWLNNRKLVLEHNMLADQGLKSYRLGMNIFGDMENQEFQAMFSHCVKSFNETDSLCTSTFLSEEEDTPLPRRVDWRKKGYVTDVKDQMSCGSCWAFSATGALEGQMFRKTGKLISLSEKQLVDCSQSFGNRGCNGGWPSKSFEYIKSNQGLEADFTYPY-----KPREETCRFNPQRVVATCSGFECLPQGDENALKKAVAKIGPISVAIDTSKHTFQLYKSGVYDEPGCSSTRLNHAVVLVGYG-NAPRGKQYWLVKNSWGIGWGDNGYIKMSRNKMNQCGIATDATYPLV 335
[Close]
BLAST of Cathepsin L vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103026492])

HSP 1 Score: 261.151 bits (666), Expect = 4.557e-84
Identity = 135/316 (42.72%), Postives = 197/316 (62.34%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ--LNSLKISNLTGSTYLPLNIKPGL----PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  +K+++G+ Y S E+E++R   ++ ++  +  HN + ++G K +++ +NH +D   +E+     N LK  N   +   P   +P +    PE  DWRD G VTE+KNQ+ CGSC+AFS+ GALEGQ+FRKTG L+ LSEQQ+VDC  +  + GC GGL+ +AF YI ++GG+E+E  YPY     +     C FK+ +AV   + +  LP GDE AL  A+  IGP+++A  A    F+ Y +G+Y D +CS    NHAVL+VGYG D E G  YW++KNSW   WG+ GY +  RNK N C +A  + YP+V
Sbjct:   25 EFHSWKIKFGRNYGSEEEESQRKMTWLANRKLVLEHNMLADQGLKSYRLGMNHFADMDNQEYQDKFANCLKPFNRNKTNPAPAFHRPAVGAAVPEEVDWRDLGYVTEIKNQEQCGSCWAFSSVGALEGQMFRKTGKLVPLSEQQLVDCSFLYGNLGCEGGLMEEAFEYIMHNGGLEAESTYPY-----EAEEKMCRFKQHEAVAYCSSYAHLPVGDEMALMSAVSVIGPVAVAIDAGRHTFQLYASGVYDDPYCSKRLSNHAVLVVGYGFDMEQGD-YWLVKNSWSTVWGDKGYIKMSRNKRNQCGIASYAVYPVV 334
[Close]
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 249.595 bits (636), Expect = 7.869e-81
Identity = 134/285 (47.02%), Postives = 183/285 (64.21%), Query Frame = 3 
Query:  390 EINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLN---IKPGL---PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD--YGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +I  HN     G   ++M +N   D T EEF Q+  L      G++  P     + P     PES DWR +G VT+VKNQ  CGSC++FSTTG+LEGQ  RKTG L+SLSEQ +VDC   +  YGC+GGL+ +AFNYIK +GGI+SE+ YPY      +    C +  K      TG+V++P GDEEAL+ A+ ++GP+S+A  A+   F +Y +GIY D  CS++ INHAVL+VGYG+DE+ G  +W++KNSWG +WGE GY R  R+  N+C +A  + YPLV
Sbjct:   18 KIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQV-MLGFRGWNGTSKAPRGATFMAPAFFEAPESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPY----KGQGVETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCSHI-INHAVLVVGYGVDEK-GDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295
[Close]
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 247.284 bits (630), Expect = 5.873e-80
Identity = 134/284 (47.18%), Postives = 180/284 (63.38%), Query Frame = 3 
Query:  393 INNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLN---IKPGL---PESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD--YGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            I+ HN     G   ++M +N  SD T EEF Q+  L      G++  P     + P     PES DWR +G VT++KNQ  CGSC++FSTTG+LEGQ  RKTG L+SLSEQ +VDC   +  +GC+GGL+ +AFNYIK +GGI+SE+ YPY     K     C +  K      TG+V++P GDEEAL  A+ ++GP+S+A  A+   F+ Y +GIY D  CS+  I+HAVL+VGYG+D E G  +W++KNSWG  WGE GY R  R+  N+C +A  S YPLV
Sbjct:   18 ISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQV-MLGFRGWNGTSKAPRGATFMAPAFFEAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPY-----KGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCSH-HIDHAVLVVGYGVD-EMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293
[Close]
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 244.973 bits (624), Expect = 4.698e-79
Identity = 135/286 (47.20%), Postives = 182/286 (63.64%), Query Frame = 3 
Query:  390 EINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKISNLT-----GSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD--YGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +I  HN     G   ++M +N   D T EEF   +  L+ SN T     G+T++ P   K   PES DWR +G VT+VK+Q  CGSC+AFSTTG+LEGQ  RKTG L+SLSEQ +VDC   +   GC GGL+  AF YIK +GGI+SE  YPY +      + NC +  K     DTGFV +P G+EEAL+ A+ ++GP+SI   A+ E F+ Y +GIY D  CSN  ++H VL+VGYG+D++    +WI+KNSWG KWG++GY    R+K N+C +A  + YPLV
Sbjct:   21 KIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFFKA--PESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTA-----KDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCSN-NLDHGVLVVGYGVDDDE-RKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297
[Close]
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 245.743 bits (626), Expect = 1.053e-78
Identity = 146/330 (44.24%), Postives = 200/330 (60.61%), Query Frame = 3 
Query:  267 ISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-------LNSLKISNLTGSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD--YGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMD--EESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            I   M+D   E+  +K  + K+YE  ++E+ R   +  +  +I  HN     G   ++M +NH  D T EEF Q       +   K+S   GST+L P N +   P + DWRDKG VTEVK+Q  CGSC+AFSTTGALEGQ  RK G L+SLSEQ +VDC   +   GC GGL+  AF Y+K +GGI+SE  YPY    T      C++  K     DTGFV +  GDE+AL+ A+ ++GP+S+A  A+ E F+ Y++G+Y +  CS+  ++H VL+VGYG+    E+G  YWI+KNSW PKWG+ GY    RN KN C +A  + YPLV
Sbjct:   21 IHDPMLD--EEWGSWKGFHQKLYEP-KQESWRRMIWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQPHKVSK--GSTFLVPQNYEA--PPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPY----TGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339
[Close]
BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007755.1 (pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 gene:ENSPMAG00000007008.1 transcript:ENSPMAT00000007755.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.46 bits (537), Expect = 1.410e-65
Identity = 128/316 (40.51%), Postives = 178/316 (56.33%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTY-----LPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDY--GCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKL-PPGDEEALREALVTIGPISIAFSA-TERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            ++  +K  YGK Y S +++  R + F  +   +  HN + ++G+  F + IN  SD    E+++    +  NL   T       PL     LPE  DWR KG VT VK Q  CGS +AFS TG+LEGQ F  TGNL SLSEQQ+VDC    Y  GC+GG    A  YI  + GI+SE  YPY     +  +  C FK        + +  + P  +EE LR+A+ ++GPI+IA +A  + FKHYK+G++++  C +   NHA+L+VGYG    SG  +WI+KNSWG  WGE GY    RNK N C +A    YP++
Sbjct:   26 QWDTWKSTYGKHYGSEQEDAHRRDVFEQNLKRVLQHNLLADEGNVSFHLGINKYSDLELHEYHEKVVGRFWNLRNGTRRRGAPFPLRSMDNLPEQVDWRLKGYVTPVKEQGLCGSSWAFSATGSLEGQHFAATGNLTSLSEQQLVDCTKSYYNNGCNGGRSERALQYIIDNNGIDSELSYPY-----EHADGKCRFKPANVATKCSSYQFVEPSSNEEVLRQAVASVGPIAIAMNADLDTFKHYKSGLFNEPSC-DKSPNHAMLVVGYG--SLSGNDFWIVKNSWGEDWGEKGYIYMIRNKDNQCGIASIGIYPII 333
[Close]
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 257.684 bits (657), Expect = 2.984e-83
Identity = 146/311 (46.95%), Postives = 196/311 (63.02%), Query Frame = 3 
Query:  321 YGKVYESIEKENERFNNFILSQ--VEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ-LNSLKI-----SNLTGSTYLP-LNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATER-FKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +GK Y +  K  E   NFI      +I  HN+    G   F++ +NH+ D T  E +Q L  LK+     S   G+T+LP  N+K  + +S DWR KG VT VKNQ  CGSC+AFSTTGALEGQ FRKTG L+SLSEQ +VDC   + + GC GGL+ +AF YIK +GGI++E+ YPY++      +  C++ +      DTGFV +P GDE AL++AL ++GPISIA  A++  F  Y  G+Y D  CS+ R++H VL VGYG D+  G  YW++KNSWGP WGE GY +  RN  + C +A  + YPLV
Sbjct:   36 HGKEYPN--KNEETMRNFIWQNNLKKIVTHNE----GKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVK--VVDSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLA-----KDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDD--GKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331
[Close]
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 242.276 bits (617), Expect = 2.426e-77
Identity = 138/329 (41.95%), Postives = 200/329 (60.79%), Query Frame = 3 
Query:  270 SSLMVDF---KSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLT------GSTYL-PLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHV--DYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            S  +V F   + ++  +KL + K Y ++ +E  R   +  +  +I  HN    +GH  F + +NH+ D T +EF    +   S+ +      GS +L P +++  +P++ DWR +G VT VKNQ  CGSC+AFSTTG+LEGQ F+KTG L+SLSEQ +VDC     + GC GGL+  AF YIK +GGI++E+ YPY     +  N  C F++      DTGFV +  GDEEAL+ A  T+GPIS+A  A    F+ Y +G+Y++  CS+  ++H VL+VGYG  +  G+ YW++KNSWG +WG  GY    RNK N C +A  + YPLV
Sbjct:   15 SGFVVKFDEDEQQWQAWKLFHTKKYTTVTEEGARKAIWRDNLKKIQKHN---AEGHS-FTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHVQ--VPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPY-----EARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQ--GSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330
[Close]
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 241.506 bits (615), Expect = 5.435e-77
Identity = 140/310 (45.16%), Postives = 185/310 (59.68%), Query Frame = 3 
Query:  321 YGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHK----KFQMEINHMSDWTPEEFNQ--LNSLKISNLTG-STYLPL-NIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            +GK Y   E++  R          I N N    K H      +++++NH +D T  EF Q  +     SN TG ST+LPL N++  LP   DWRDKG VT VKNQ  CGSC+AFS+TG+LEGQ FRKTG L+SLSEQ +VDC   + + GC GGL+  AF YIK + GI++EQ YPY +      +  C+FK      T TG+  +  G E  L+ A+ T+GPIS+A  A    F+ YK G+Y +  CS+ +++H VL VGYG   E G  YW++KNSWG  WG NGY +  RNK N C +A  + YPLV
Sbjct:   34 HGKTYTGEEEDLRR---------AIWNDNLEIVKKHNAENHSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTFLPLSNVQ--LPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTA-----RDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGA--EDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325
[Close]
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 235.728 bits (600), Expect = 8.539e-75
Identity = 129/316 (40.82%), Postives = 192/316 (60.76%), Query Frame = 3 
Query:  294 SEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQ--LNSLKISNLTG---STYLP-LNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            SE+  +K  +GK Y  + +E  R   +  +  +I  HN         ++M +NH+ D T +EF    L      N T    +TY+P  N+K  +P S DW  KG VT VKNQ  CGSC+AFSTTG++EGQ FRKTG+L+SLSEQ ++DC   + + GC GGL+ +AF YI+ +GGI++E  YPY+         +C+F         TG+  +P G E+AL+ A+ T+GP+S+A  A++ ++ Y +G+Y + +CS+ +++H VL++GYG    +G  YW++KNSWG  WG  GY    RNK N C +A ++ YPLV
Sbjct:   25 SEWVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAE----DHSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNVK--IPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLG-----QQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQ-WQFYSSGVYDNPYCSSTQLDHGVLVIGYG--NYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326
[Close]
BLAST of Cathepsin L vs. Ensembl Nematostella
Match: EDO42751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K3])

HSP 1 Score: 196.052 bits (497), Expect = 5.235e-60
Identity = 104/213 (48.83%), Postives = 133/213 (62.44%), Query Frame = 3 
Query:  555 LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYH--DDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNM 1187
            +PES DWRDKG VT VKNQ  CGSC+AFSTTG +EGQ   KTG L+SLSEQ++VDCD +D GC GGL  +A+  I+  GG+ESE +YPY     K  +  C F + +   T    V +   DE+ +   L   GPISI  +A    + Y  GI H    +C+   +NH VL+VGYG+  ++GTPYWIIKNSWGP WGE GY+   R    C +
Sbjct:   63 IPESVDWRDKGVVTPVKNQGSCGSCWAFSTTGNIEGQYAIKTGKLVSLSEQELVDCDTIDKGCEGGLPSNAYKQIEKLGGLESESDYPY-----KGADSKCKFNKAEVKVTINSSVVISK-DEKEIAAWLAKNGPISIGINAN-AMQFYMGGIAHPWKIFCNPSSLNHGVLIVGYGV--KNGTPYWIIKNSWGPSWGEKGYYLIYRGGGCCGL 266
[Close]
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 268.085 bits (684), Expect = 9.532e-87
Identity = 138/317 (43.53%), Postives = 204/317 (64.35%), Query Frame = 3 
Query:  297 EFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNS---LKISNLT----GSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDC--DHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            EF  ++L++G+ Y S  +E +R   ++ ++  +  HN + ++G K +++ + + +D   EE+ +L S   L   N +    GST+  L     LP + DWRDKG VT+VK+QK CGSC+AFS TG+LEGQ FRKTG L+SLSEQQ+VDC  D+ + GC GGL+ DAF YI+ +GGI++E+ YPY     +  +  C +K      T TG+V +  GDE+AL+EA+ TIGPIS+   A+   F+ Y++G+Y +  CS+  ++H VL VGYG   E+G  YW++KNSWG  WG+ GY +  +NK N C +A  + YPLV
Sbjct:   30 EFHAWRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRGSTFFRLPENKDLPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPY-----EAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYG--SENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339
[Close]
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246])

HSP 1 Score: 232.646 bits (592), Expect = 4.319e-73
Identity = 126/289 (43.60%), Postives = 178/289 (61.59%), Query Frame = 3 
Query:  378 LSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQL----NSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVD--YGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSAT-ERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEE--SGTPYWIIKNSWGPKWGENGYFRFERNK-NMCNMAYNSYYPLV 1214
            L ++E+  HN     G   +++ +NH  D T EEF Q+       +    +GS ++  N     P + DWRDKG VT VK+Q  CGSC+AFSTTGALEGQ FRKTG L+SLSEQ +VDC   +   GC+GGL+  AF Y+K + G++SE  YPY  G   +P   C +  + +   DTGFV +P G E AL +A+ ++GP+S+A  A  E F+ Y++GIY +  CS+  ++H VL+VGYG + E   G  YWI+KNSW  KWG+ G+    +++ N C +A  + YPLV
Sbjct:   55 LRKIEL--HNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEPNFLEA-PRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPY-KGTDDQP---CQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336
[Close]
BLAST of Cathepsin L vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175])

HSP 1 Score: 224.557 bits (571), Expect = 6.909e-70
Identity = 131/310 (42.26%), Postives = 182/310 (58.71%), Query Frame = 3 
Query:  309 FKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEE-FNQLNSLKI-SNLTGSTYLPLNIKPG--LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKN-MCNMAYNSYYPLV 1214
            +K  + K Y S E++  R + +  + + I  HN  +  G   + + +NHM D T EE   Q  SL+  +NL    +L +       +P+  DWR K  VT VK Q  CGSC+AFS  GALEGQL RKTG L+ LS Q +VDC   + ++GC+GG +  AF Y+  + GI+S+  YPYV G+T+    NC++  +      + +  LP GDE AL+EA+ TIGPIS+A  AT  RF  Y++G+Y D  CS   +NH VL VGYG    +G  YW++KNSWG  +GE GY R  RNKN  C +A    YP++
Sbjct:   38 WKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNLKREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYV-GVTQ----NCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQ-NVNHGVLAVGYG--TLNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYPIM 339
[Close]
BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 223.402 bits (568), Expect = 1.033e-69
Identity = 131/319 (41.07%), Postives = 181/319 (56.74%), Query Frame = 3 
Query:  300 FAKFKLQYGKVYE---SIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNS-------LKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            F+   L  G V +   +I +EN R          IN+HNQ F  G + F M +N   D T +E+  L         +K      +  L  N +       D+R+ G VTEVK+Q YCGSC+AFSTTGA+EGQ+ +KTG L+SLSEQ +VDC   +  +GCSG  +  A++Y+  S G+++   YPY S + +   P C +  + AV     +  +P GDE+AL +A+ TIGPI++A  A    F  Y +GIY +  C   R++HAVLLVGYG +E  G  YWIIKNSWG  WGE GY R  RN  N C +A  + YP++
Sbjct:   14 FSANSLLIGAVLQLKGAIWEENHRM---------INDHNQRFLTGKRPFSMGMNKYGDLTGQEYRVLQGAVMNAQFVKRGKEVSARRLRYNARKSEAGFVDYRNMGYVTEVKDQGYCGSCWAFSTTGAIEGQIVKKTGQLLSLSEQNLVDCSRPYGTHGCSGAWMASAYDYV-LSNGLQTTDSYPYTS-VVRDTQP-CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEE--GQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 318
[Close]
BLAST of Cathepsin L vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 221.476 bits (563), Expect = 6.923e-69
Identity = 128/311 (41.16%), Postives = 178/311 (57.23%), Query Frame = 3 
Query:  315 LQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNS-------LKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCD--HVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE-RFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERN-KNMCNMAYNSYYPLV 1214
            + Y +   +I +EN R          IN+HNQ F  G + F M +N   D T +E+  L         +K      +  L  N +       D+R+ G VTEVK+Q YCGSC+AFSTTGA+EGQ+ +KTG L+SLSEQ +VDC   +  +GCSG  +  A++Y+  S G+++   YPY S +  +P   C +  + AV     +  +P GDE+AL +A+ TIGPI++A  A    F  Y +GIY +  C   R++HAVLLVGYG +E  G  YWIIKNSWG  WGE GY R  RN  N C +A  + YP++
Sbjct:   27 INYEERRRAIWEENHRM---------INDHNQRFLTGKRPFSMGMNKYGDLTGQEYRVLQGAVMNAQFVKRGKEVSARRLRYNARKSEAGFVDYRNMGYVTEVKDQGYCGSCWAFSTTGAIEGQIVKKTGQLLSLSEQNLVDCSRPYGTHGCSGAWMASAYDYV-LSNGLQTTDSYPYTS-VDTQP---CFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEE--GQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 321
[Close]
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000034294.1 (SMESG000034294.1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 330/343 (96.21%), Postives = 334/343 (97.38%), Query Frame = 3 
Query:  186 ANAEIWEPDRNLSNVHQSHANTKFSRKISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            ANAEIWEPDRNL NV QSHAN KFSRKISSLMVDFKSEFAKFK QYGKVYES+E+ENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWT EEFNQLNSLKISNL GSTYLPLNIKP LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATE+FKHYKNGIYHDDWCSNVRINH VLLVGYG DEESGTPYWIIKNSWGPKWGE+GYFRFERNKNMCNMAYNSYYPLV
Sbjct:   17 ANAEIWEPDRNLPNVRQSHANPKFSRKISSLMVDFKSEFAKFKRQYGKVYESVEEENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTQEEFNQLNSLKISNLNGSTYLPLNIKPDLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATEQFKHYKNGIYHDDWCSNVRINHGVLLVGYGTDEESGTPYWIIKNSWGPKWGESGYFRFERNKNMCNMAYNSYYPLV 359
[Close]
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000054075.1 (SMESG000054075.1)

HSP 1 Score: 677.552 bits (1747), Expect = 0.000e+0
Identity = 323/343 (94.17%), Postives = 330/343 (96.21%), Query Frame = 3 
Query:  186 ANAEIWEPDRNLSNVHQSHANTKFSRKISSLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            ANAEIWE DR+L NV QSHAN KFSRKISSL  D KSEFAKFK +YGKVYES+E+ENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWT EEFNQLNSLKISNLTGSTYLPLNIKP LPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDA NYIKYSGGIESEQEYPY+SGL KKPNPNCNFKEK+AVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYG DEESGTPYWIIKNSWGPKWGE+GYFRFERNKNMCNMAYNSYYPLV
Sbjct:   17 ANAEIWEIDRSLPNVRQSHANPKFSRKISSLTDDLKSEFAKFKRKYGKVYESVEEENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTREEFNQLNSLKISNLTGSTYLPLNIKPDLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDALNYIKYSGGIESEQEYPYISGLKKKPNPNCNFKEKEAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGTDEESGTPYWIIKNSWGPKWGESGYFRFERNKNMCNMAYNSYYPLV 359
[Close]
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063517.1 (SMESG000063517.1)

HSP 1 Score: 417.927 bits (1073), Expect = 2.235e-145
Identity = 194/314 (61.78%), Postives = 237/314 (75.48%), Query Frame = 3 
Query:  273 SLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            SL+  +  EF  FK +Y K Y S+ +EN RF NFI S +EIN+HNQ++E G K +++ INH+SDW+ EE  QL  LK SNLTGS+YL  N+K  LP+SFDWR+KGAVTEVKNQ +CGSCYAF+TTG LE Q++RKTG LISLSEQQIVDCD  D GC GG V DA +YIK +GGIE+E+ YPY+S  T KPN  CNF + K V TDTGFV++P  DE  ++EALVTIGPIS+A SAT+  K Y +GI+H+D C  +++NHAVL+VGYG D+ SGTPYWIIKNSW   WGENGYFR  RN N C +A    YPLV
Sbjct:   45 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 358
[Close]
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063517.1 (SMESG000063517.1)

HSP 1 Score: 417.542 bits (1072), Expect = 2.950e-145
Identity = 194/314 (61.78%), Postives = 237/314 (75.48%), Query Frame = 3 
Query:  273 SLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            SL+  +  EF  FK +Y K Y S+ +EN RF NFI S +EIN+HNQ++E G K +++ INH+SDW+ EE  QL  LK SNLTGS+YL  N+K  LP+SFDWR+KGAVTEVKNQ +CGSCYAF+TTG LE Q++RKTG LISLSEQQIVDCD  D GC GG V DA +YIK +GGIE+E+ YPY+S  T KPN  CNF + K V TDTGFV++P  DE  ++EALVTIGPIS+A SAT+  K Y +GI+H+D C  +++NHAVL+VGYG D+ SGTPYWIIKNSW   WGENGYFR  RN N C +A    YPLV
Sbjct:   42 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSGEELAQLTKLKQSNLTGSSYLSSNVKIDLPDSFDWREKGAVTEVKNQGFCGSCYAFATTGTLEAQIWRKTGKLISLSEQQIVDCDTNDDGCDGGFVQDALSYIKSNGGIENEESYPYISSETFKPNSKCNFFKSKVVATDTGFVQMPANDETKMKEALVTIGPISVAISATKSLKRYTSGIFHEDECDKLKLNHAVLIVGYGTDQTSGTPYWIIKNSWSSFWGENGYFRLPRNINACKVAMMPVYPLV 355
[Close]
BLAST of Cathepsin L vs. Planmine SMEST
Match: SMESG000063471.1 (SMESG000063471.1)

HSP 1 Score: 402.905 bits (1034), Expect = 1.685e-139
Identity = 190/314 (60.51%), Postives = 229/314 (72.93%), Query Frame = 3 
Query:  273 SLMVDFKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKFQMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKGAVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDYGCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGTDTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSNVRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNMAYNSYYPLV 1214
            SL+  +  EF  FK +Y K Y S+ +EN RF NFI S +EIN+HNQ++E G K +++ INH+SDW+ EE +QL  LK SNLTGS+YL  ++K  LP+SFDWR+KGAVTEVK+Q  CGSCYAF+ TG LE Q++RKTG LISLSEQQIVDCD  D  C GG V DA +YIK +GGIE+E+ YPYVSG T   NP CNF + K V TDTGFVK+P  DEE L+EALVTIGPIS   SA +    Y  GI++D  C  +R+NHAVL+VGYG D+ SGTPYWIIKNSW   WGE GYFR  RN N C +A    YPLV
Sbjct:   42 SLLSRYDGEFQTFKQRYNKSYSSMHEENSRFLNFISSLLEINHHNQLYENGQKSYEIGINHLSDWSDEELSQLTKLKQSNLTGSSYLSSSVKIDLPDSFDWREKGAVTEVKDQGKCGSCYAFAATGTLEAQIWRKTGKLISLSEQQIVDCDTNDNNCYGGFVQDALSYIKSNGGIENEENYPYVSGKTADMNPKCNFVKSKVVATDTGFVKMPANDEEKLKEALVTIGPISALLSAPKSLIKYSKGIFYDKECEKLRVNHAVLIVGYGTDQTSGTPYWIIKNSWNASWGEKGYFRLPRNINACKIASVPVYPLV 355
The following BLAST results are available for this feature:
BLAST of Cathepsin L vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CTSV1.318e-7644.84cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSV1.318e-7644.84cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538][more]
CTSL4.171e-7340.79cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSL4.171e-7340.79cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537][more]
CTSH1.130e-6842.41cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535][more]
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BLAST of Cathepsin L vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpl-11.242e-8443.41CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-11.385e-6451.72CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
cpl-11.385e-6451.72CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H... [more]
tag-1961.988e-5948.20pep chromosome:WBcel235:V:8594914:8597500:1 gene:W... [more]
tag-1961.988e-5948.20pep chromosome:WBcel235:V:8594914:8597469:1 gene:W... [more]
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BLAST of Cathepsin L vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cp16.515e-8443.17gene:FBgn0013770 transcript:FBtr0087592[more]
Cp11.009e-8343.17gene:FBgn0013770 transcript:FBtr0087593[more]
Cp14.697e-8242.63gene:FBgn0013770 transcript:FBtr0339955[more]
Cp11.374e-7450.45gene:FBgn0013770 transcript:FBtr0304021[more]
CG48475.101e-7140.38gene:FBgn0034229 transcript:FBtr0086934[more]
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BLAST of Cathepsin L vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl.18.315e-8643.85cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
ctsl.18.315e-8643.85cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
ctsl.18.315e-8643.85cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61][more]
si:dkey-269i1.42.394e-7740.92si:dkey-269i1.4 [Source:ZFIN;Acc:ZDB-GENE-121214-3... [more]
si:dkey-239j18.33.002e-7740.92si:dkey-239j18.3 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
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BLAST of Cathepsin L vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsk1.795e-7240.00cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
ctsk2.140e-7240.00cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac... [more]
fcrl28.669e-7245.58Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
fcrl29.263e-7245.58Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590... [more]
harbi18.537e-6539.75harbinger transposase derived 1 [Source:Xenbase;Ac... [more]
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BLAST of Cathepsin L vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ctsl5.825e-7541.74cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsl5.825e-7541.74cathepsin L [Source:MGI Symbol;Acc:MGI:88564][more]
Ctsh8.572e-6942.22cathepsin H [Source:MGI Symbol;Acc:MGI:107285][more]
Ctsk1.902e-6739.43cathepsin K [Source:MGI Symbol;Acc:MGI:107823][more]
Ctsll37.691e-6741.90cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917... [more]
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BLAST of Cathepsin L vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q26636|CATL_SARPE1.433e-8443.24Cathepsin L OS=Sarcophaga peregrina OX=7386 PE=1 S... [more]
sp|O45734|CPL1_CAEEL1.580e-8343.41Cathepsin L-like OS=Caenorhabditis elegans OX=6239... [more]
sp|Q95029|CATL_DROME1.012e-8243.17Cathepsin L OS=Drosophila melanogaster OX=7227 GN=... [more]
sp|P05167|ALEU_HORVU1.035e-7743.27Thiol protease aleurain OS=Hordeum vulgare OX=4513... [more]
sp|Q28944|CATL1_PIG1.015e-7641.01Cathepsin L1 OS=Sus scrofa OX=9823 GN=CTSL PE=2 SV... [more]
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BLAST of Cathepsin L vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183T8C81.558e-9052.38Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A0X3NKX43.826e-9052.38Cathepsin L OS=Schistocephalus solidus OX=70667 GN... [more]
A0A0N5CEB41.113e-8744.41Uncharacterized protein OS=Strongyloides papillosu... [more]
R4WD682.087e-8746.37Cathepsin L OS=Riptortus pedestris OX=329032 PE=2 ... [more]
B3SVE22.626e-8745.29Cathepsin L-like protease OS=Strongylus vulgaris O... [more]
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BLAST of Cathepsin L vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl.13.612e-8843.35cathepsin L1-like [Source:NCBI gene;Acc:103023607][more]
ENSAMXT00000001970.21.224e-8644.94cathepsin L1-like [Source:NCBI gene;Acc:103022163][more]
ENSAMXT00000040914.14.135e-8543.45pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000034892.11.232e-8444.30cathepsin L1-like [Source:NCBI gene;Acc:107196839][more]
ctsl.14.557e-8442.72cathepsin L1-like [Source:NCBI gene;Acc:103026492][more]
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BLAST of Cathepsin L vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000003800.17.869e-8147.02pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g... [more]
ENSPMAT00000010475.15.873e-8047.18pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ... [more]
ENSPMAT00000011285.14.698e-7947.20pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen... [more]
ENSPMAT00000006499.11.053e-7844.24pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g... [more]
ENSPMAT00000007755.11.410e-6540.51pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 g... [more]
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BLAST of Cathepsin L vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Cathepsin L vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO458522.984e-8346.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO367272.426e-7741.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO464655.435e-7745.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459538.539e-7540.82Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO427515.235e-6048.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cathepsin L vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ctsl.19.532e-8743.53cathepsin L1 [Source:NCBI gene;Acc:101171789][more]
ctsl4.319e-7343.60cathepsin L [Source:NCBI gene;Acc:100049246][more]
ctss2.16.909e-7042.26cathepsin S [Source:NCBI gene;Acc:101165175][more]
cts121.033e-6941.07cathepsin L1-like [Source:NCBI gene;Acc:101170830][more]
cts126.923e-6941.16cathepsin L1-like [Source:NCBI gene;Acc:101170830][more]
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BLAST of Cathepsin L vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000034294.10.000e+096.21SMESG000034294.1[more]
SMESG000054075.10.000e+094.17SMESG000054075.1[more]
SMESG000063517.12.235e-14561.78SMESG000063517.1[more]
SMESG000063517.12.950e-14561.78SMESG000063517.1[more]
SMESG000063471.11.685e-13960.51SMESG000063471.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30001027 ID=SMED30001027|Name=Cathepsin L|organism=Schmidtea mediterranea sexual|type=transcript|length=1243bp
TAATAATTTGCACATCAAACCGTAATAATAACGGATCCGTACAATTTCAT
CAATATAAAATATTACACAACAAATGCGACTTGCATCGACAATTCATATA
AAAATCTCCAACTTTCACTACTATTCATAAATTACAAATGATCTCCTCAG
TTGTATTGTTATTTTCTATCTCAGTCGCATTCCTAGCAAATGCCGAAATC
TGGGAACCAGATCGAAACCTTTCAAACGTCCATCAGAGTCACGCTAATAC
AAAGTTTTCCAGGAAAATTTCATCTTTGATGGTGGATTTCAAGTCAGAAT
TCGCCAAATTTAAATTACAATATGGAAAGGTTTACGAGTCAATTGAGAAA
GAAAACGAAAGATTCAACAATTTCATATTATCTCAAGTTGAAATAAACAA
TCACAATCAAATGTTTGAAAAGGGTCACAAGAAATTCCAAATGGAAATTA
ATCACATGAGTGATTGGACTCCAGAAGAATTCAATCAACTTAATAGCCTA
AAGATATCTAATCTCACCGGTTCGACATATTTGCCATTGAACATAAAGCC
TGGCCTTCCAGAGTCTTTTGATTGGAGAGACAAAGGTGCAGTTACTGAAG
TCAAAAATCAGAAATATTGCGGTTCGTGCTACGCATTCTCTACGACAGGC
GCGTTAGAAGGTCAACTATTCAGAAAAACCGGAAATTTGATAAGTTTATC
TGAACAACAAATTGTTGATTGTGATCATGTTGATTATGGTTGTAGTGGTG
GCTTAGTACCAGACGCTTTCAATTACATCAAATACTCCGGAGGAATTGAA
TCCGAACAAGAGTATCCATATGTATCTGGATTGACAAAGAAACCAAATCC
AAATTGTAATTTCAAAGAAAAAAAAGCAGTTGGAACAGATACCGGATTTG
TGAAATTGCCTCCTGGAGATGAAGAGGCTTTGAGAGAAGCTTTAGTGACA
ATAGGCCCGATTTCGATAGCGTTTTCCGCCACTGAGCGATTCAAACATTA
CAAAAATGGAATTTACCATGATGATTGGTGTTCAAATGTCCGTATCAATC
ATGCAGTTTTACTCGTCGGATATGGAATGGATGAAGAATCAGGAACGCCT
TATTGGATAATAAAAAATAGTTGGGGACCCAAATGGGGAGAAAACGGATA
TTTCCGTTTCGAAAGAAATAAAAACATGTGCAACATGGCATACAATTCAT
ACTATCCATTGGTTTGATTGAACGACTTCTTATGAGTGTGTGC
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protein sequence of SMED30001027-orf-1

>SMED30001027-orf-1 ID=SMED30001027-orf-1|Name=SMED30001027-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=360bp
MISSVVLLFSISVAFLANAEIWEPDRNLSNVHQSHANTKFSRKISSLMVD
FKSEFAKFKLQYGKVYESIEKENERFNNFILSQVEINNHNQMFEKGHKKF
QMEINHMSDWTPEEFNQLNSLKISNLTGSTYLPLNIKPGLPESFDWRDKG
AVTEVKNQKYCGSCYAFSTTGALEGQLFRKTGNLISLSEQQIVDCDHVDY
GCSGGLVPDAFNYIKYSGGIESEQEYPYVSGLTKKPNPNCNFKEKKAVGT
DTGFVKLPPGDEEALREALVTIGPISIAFSATERFKHYKNGIYHDDWCSN
VRINHAVLLVGYGMDEESGTPYWIIKNSWGPKWGENGYFRFERNKNMCNM
AYNSYYPLV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR039417Peptidase_C1A_papain-like
IPR038765Papain-like_cys_pep_sf
IPR000668Peptidase_C1A_C
IPR013201Prot_inhib_I29
IPR000169Pept_cys_AS
IPR025660Pept_his_AS
IPR025661Pept_asp_AS
Vocabulary: biological process
TermDefinition
GO:0006508proteolysis
Vocabulary: molecular function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0008233peptidase activity
GO:0016787hydrolase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000668Peptidase C1A, papain C-terminalPRINTSPR00705PAPAINcoord: 305..315
score: 61.24
coord: 158..173
score: 57.14
coord: 322..328
score: 75.14
IPR000668Peptidase C1A, papain C-terminalSMARTSM00645pept_c1coord: 140..358
e-value: 2.3E-111
score: 386.0
IPR000668Peptidase C1A, papain C-terminalPFAMPF00112Peptidase_C1coord: 140..357
e-value: 1.3E-78
score: 264.1
IPR013201Cathepsin propeptide inhibitor domain (I29)SMARTSM00848Inhibitor_I29_2coord: 55..115
e-value: 2.3E-17
score: 73.7
IPR013201Cathepsin propeptide inhibitor domain (I29)PFAMPF08246Inhibitor_I29coord: 55..115
e-value: 3.7E-12
score: 46.5
NoneNo IPR availableGENE3DG3DSA:3.90.70.10coord: 48..359
e-value: 1.3E-105
score: 355.5
NoneNo IPR availablePANTHERPTHR12411:SF631coord: 47..358
NoneNo IPR availablePANTHERPTHR12411CYSTEINE PROTEASE FAMILY C1-RELATEDcoord: 47..358
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..19
score: 0.76
IPR025661Cysteine peptidase, asparagine active sitePROSITEPS00640THIOL_PROTEASE_ASNcoord: 322..341
IPR025660Cysteine peptidase, histidine active sitePROSITEPS00639THIOL_PROTEASE_HIScoord: 303..313
IPR000169Cysteine peptidase, cysteine active sitePROSITEPS00139THIOL_PROTEASE_CYScoord: 158..169
IPR039417Papain-like cysteine endopeptidaseCDDcd02248Peptidase_C1Acoord: 141..357
e-value: 4.12231E-113
score: 325.733
IPR038765Papain-like cysteine peptidase superfamilySUPERFAMILYSSF54001Cysteine proteinasescoord: 51..358