TNF receptor-associated factor 1-like

Overview


Name	TNF receptor-associated factor 1-like
Smed ID	SMED30001022
Length (bp)	730

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of TNF receptor-associated factor 1-like (SMED30001022) t-SNE clustered cells

Violin plots show distribution of expression levels for TNF receptor-associated factor 1-like (SMED30001022) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of TNF receptor-associated factor 1-like (SMED30001022) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for TNF receptor-associated factor 1-like (SMED30001022) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001022

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parenchyma	SMED30001022	SMESG000049895.1	dd_Smed_v4_6017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30001022	SMESG000049895.1	dd_Smed_v4_6017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior side	SMED30001022	SMESG000049895.1	dd_Smed_v4_6017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
posterior muscle cell	SMED30001022	SMESG000049895.1	dd_Smed_v4_6017_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30001022	SMESG000049895.1	dd_Smed_v4_6017_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 63.929 bits (154), Expect = 3.132e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  244 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 456

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 63.929 bits (154), Expect = 4.080e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  302 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 514

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 63.929 bits (154), Expect = 4.080e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  302 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 514

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 63.929 bits (154), Expect = 4.231e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  327 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 539

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 63.929 bits (154), Expect = 4.231e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  327 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 539

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80])

HSP 1 Score: 47.3654 bits (111), Expect = 4.376e-6
Identity = 28/81 (34.57%), Postives = 41/81 (50.62%), Query Frame = 1

Query:  343 WQIDKISQQKRKE------WIYSKPFYSESSGYKM--CLAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTD 561
            W+IDK+ Q+  +        I+S PF S   GYKM  C  +          I +   L++G+FD  LEWPF  A+ I++ D
Sbjct:  267 WKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLD 347

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257])

HSP 1 Score: 75.0998 bits (183), Expect = 4.516e-15
Identity = 56/230 (24.35%), Postives = 111/230 (48.26%), Query Frame = 1

Query:   10 LQQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQL-RVNKKLEIEKCDNDIRL------IQTFGNEIFIKFGFFEWQIDKISQQKRKEWI------YSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            L+QK+  M+     ++  + E   E++ L+   R++R E+ET  G++  +R  +  ++ +    +     +   +QQL R +  + +    +D+RL      +Q      F   G   W+I    ++K++  +      YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L+WPFK  VT+ + D G   K +   +   P+ + + +P+   N+ 
Sbjct:  314 LEQKLVSMQMLMSSHSEKLLEVEMELRELR-PLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSV----HDVRLAEMDLKLQVLETASF--NGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIA 536

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1)

HSP 1 Score: 55.0694 bits (131), Expect = 1.424e-8
Identity = 35/116 (30.17%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I   S+++      R   ++S  FY+   GYKMCL I  N        ++ + F +MRG  D  L+WPF   VT+ + D  N    I  + RP  + + + +P ++ N+ 
Sbjct:  126 GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID-AFRPDISSSSFQRPVSDMNIA 240

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
Match: AL844899.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28760787:-1 gene:ENSDARG00000111038.1 transcript:ENSDART00000183806.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844899.1)

HSP 1 Score: 55.0694 bits (131), Expect = 1.424e-8
Identity = 35/116 (30.17%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I   S+++      R   ++S  FY+   GYKMCL I  N        ++ + F +MRG  D  L+WPF   VT+ + D  N    I  + RP  + + + +P ++ N+ 
Sbjct:  126 GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID-AFRPDISSSSFQRPVSDMNIA 240

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 55.4546 bits (132), Expect = 1.797e-8
Identity = 49/207 (23.67%), Postives = 92/207 (44.44%), Query Frame = 1

Query:   58 RNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            + +E +   M+A+  ++R  + ++E  +  + Q+   +   ++          Q+ E +Q LR     E++ C  D               G F W+I + S+++      R   ++S  FYS   GYKMCL +  N        ++ + F +M+GK+D  L+WPF   VT+ + D  N    I  + RP  +   + +P +  N+ 
Sbjct:  322 KEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDL----------QLAESEQSLR-----ELQFCTYD---------------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIID-AFRPDVSSTSFQRPISEMNIA 497

[Close]

Query:   58 RNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            + +E +   M+A+  ++R  + ++E  +  + Q+   +   ++          Q+ E +Q LR     E++ C  D               G F W+I + S+++      R   ++S  FYS   GYKMCL +  N        ++ + F +M+GK+D  L+WPF   VT+ + D  N    I  + RP  +   + +P +  N+ 
Sbjct:  322 KEVERSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDL----------QLAESEQSLR-----ELQFCTYD---------------GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIID-AFRPDVSSTSFQRPISEMNIA 497

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 65.4698 bits (158), Expect = 1.062e-11
Identity = 60/235 (25.53%), Postives = 107/235 (45.53%), Query Frame = 1

Query:   16 QKMCEMEAKELENA----RNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEF--KQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            Q++ E +A +L++     RN+ +T  E   +K+ Y SL++ +            Q+E +  N    +      QI  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  V++ + D G   + +   +   P  + + KP+   N+  G  V + 
Sbjct:  290 QRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLS-----------QLEVMAKNAASWNPGVLETQINRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 507

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 65.0846 bits (157), Expect = 1.292e-11
Identity = 60/235 (25.53%), Postives = 107/235 (45.53%), Query Frame = 1

Query:   16 QKMCEMEAKELENA----RNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEF--KQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            Q++ E +A +L++     RN+ +T  E   +K+ Y SL++ +            Q+E +  N    +      QI  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  V++ + D G   + +   +   P  + + KP+   N+  G  V + 
Sbjct:  315 QRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLS-----------QLEVMAKNAASWNPGVLETQINRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 532

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Match: hspb6 (heat shock protein family B (small) member 6 [Source:Xenbase;Acc:XB-GENE-876273])

HSP 1 Score: 56.6102 bits (135), Expect = 7.786e-9
Identity = 37/116 (31.90%), Postives = 59/116 (50.86%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I  ++ +       R   +YS  FY+   GYK+CL I  N        ++ + F +M+G++D  L WPFK+ VT  + D  N   ++  + RP  T A + +P N+ NV 
Sbjct:  230 GVFLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDHNNR-DSVFDAFRPDVTSASFQRPINDMNVA 344

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415])

HSP 1 Score: 50.8322 bits (120), Expect = 8.793e-7
Identity = 34/116 (29.31%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I +  +++      R   ++S PFY+   GYKMCL I  N      + ++ + F +M+G  D  L WPF   VT+ + D  N    I  + RP  + + + +P +  N+ 
Sbjct:  305 GVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVID-AFRPDVSSSSFQRPISEMNIA 419

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415])

HSP 1 Score: 50.447 bits (119), Expect = 1.103e-6
Identity = 34/116 (29.31%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I +  +++      R   ++S PFY+   GYKMCL I  N      + ++ + F +M+G  D  L WPF   VT+ + D  N    I  + RP  + + + +P +  N+ 
Sbjct:  332 GVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQNNREHVID-AFRPDVSSSSFQRPISEMNIA 446

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 63.1586 bits (152), Expect = 4.542e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  326 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQAARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 538

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 63.1586 bits (152), Expect = 4.547e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  301 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQAARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 513

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 63.1586 bits (152), Expect = 4.547e-11
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  301 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQAARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 513

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
Match: Traf1 (TNF receptor-associated factor 1 [Source:MGI Symbol;Acc:MGI:101836])

HSP 1 Score: 55.4546 bits (132), Expect = 1.765e-8
Identity = 49/221 (22.17%), Postives = 103/221 (46.61%), Query Frame = 1

Query:   28 EMEAKELENARNMEETNKEMKALKNEYRSLRSEMETN----TGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            E+  + L   + + +  ++++   N    L  E+E +      +I+Q ++  E + ++ +++  E +Q    + Q+       + K ++ +RL++    +     G F W+I  ++++       R   ++S  FY+   GYK+CL +  N        ++ +   +MRG++D  L WPF+  VT  + D  N    I  + RP  + A + +P + TNV 
Sbjct:  168 ELALQHLVKEKLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIHQSQLDREHI-LSLEQRVVELQQTLAQKDQV-------LGKLEHSLRLMEEASFD-----GTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID-AFRPDLSSASFQRPQSETNVA 374

[Close]

Query:   28 EMEAKELENARNMEETNKEMKALKNEYRSLRSEMETN----TGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            E+  + L   + + +  ++++   N    L  E+E +      +I+Q ++  E + ++ +++  E +Q    + Q+       + K ++ +RL++    +     G F W+I  ++++       R   ++S  FY+   GYK+CL +  N        ++ +   +MRG++D  L WPF+  VT  + D  N    I  + RP  + A + +P + TNV 
Sbjct:  168 ELALQHLVKEKLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIHQSQLDREHI-LSLEQRVVELQQTLAQKDQV-------LGKLEHSLRLMEEASFD-----GTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID-AFRPDLSSASFQRPQSETNVA 374

[Close]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2)

HSP 1 Score: 63.929 bits (154), Expect = 2.032e-10
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  327 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 539

[Close]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 3.177e-10
Identity = 54/220 (24.55%), Postives = 104/220 (47.27%), Query Frame = 1

Query:   55 ARNMEETNKEMKALKN---EYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFK-QIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNV--GVQVIIG 666
            A  ++E +KE++  +    E  S++S +E+    + ++   ++K      + +   + Q+  H Q L V+   +I   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G+  + +   +   P  + + KP+   N+  G  V + 
Sbjct:  326 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE-SVDKSAGQAARNTGLLESQLSRHDQMLSVH---DIRLADMDLRF-QVLETASY--NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVA 538

[Close]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Match: sp|P39428|TRAF1_MOUSE (TNF receptor-associated factor 1 OS=Mus musculus OX=10090 GN=Traf1 PE=1 SV=2)

HSP 1 Score: 55.4546 bits (132), Expect = 1.234e-7
Identity = 49/221 (22.17%), Postives = 103/221 (46.61%), Query Frame = 1

Query:   28 EMEAKELENARNMEETNKEMKALKNEYRSLRSEMETN----TGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            E+  + L   + + +  ++++   N    L  E+E +      +I+Q ++  E + ++ +++  E +Q    + Q+       + K ++ +RL++    +     G F W+I  ++++       R   ++S  FY+   GYK+CL +  N        ++ +   +MRG++D  L WPF+  VT  + D  N    I  + RP  + A + +P + TNV 
Sbjct:  168 ELALQHLVKEKLLAQLEEKLRVFANIVAVLNKEVEASHLALAASIHQSQLDREHI-LSLEQRVVELQQTLAQKDQV-------LGKLEHSLRLMEEASFD-----GTFLWKITNVTKRCHESVCGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID-AFRPDLSSASFQRPQSETNVA 374

[Close]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Match: sp|Q6IWL4|TRAF6_DANRE (TNF receptor-associated factor 6 OS=Danio rerio OX=7955 GN=traf6 PE=1 SV=2)

HSP 1 Score: 53.9138 bits (128), Expect = 4.368e-7
Identity = 27/110 (24.55%), Postives = 53/110 (48.18%), Query Frame = 1

Query:  331 GFFEWQIDKISQQKRKE------WIYSKPFYSESSGYKMCLAINVRXXXXXXXX---XXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSD-RPTDAGWMKPS 630
            G + W+++  S   R +       ++S PFY+   GYK+CL ++++            +  H M+G+FD +L WP +  + + V D   G   I+  + +P    + +P+
Sbjct:  375 GIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETKPDLQAFQRPT 484

[Close]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Match: sp|Q13077|TRAF1_HUMAN (TNF receptor-associated factor 1 OS=Homo sapiens OX=9606 GN=TRAF1 PE=1 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 4.547e-7
Identity = 49/205 (23.90%), Postives = 95/205 (46.34%), Query Frame = 1

Query:   64 MEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            + E   +++  +N    L  E+E +  A+      I + +++ ++     +++ E QQ L   K   + K +  +RL++    +     G F W+I  ++++       R   ++S  FY+   GYK+CL +  N        ++ +   +MRG++D  L WPF+  VT  + D  N    I  + RP  + A + +P + TNV 
Sbjct:  187 LAELEGKLRVFENIVAVLNKEVEASHLALA---TSIHQSQLDRERILSLEQRVVELQQTL-AQKDQALGKLEQSLRLMEEASFD-----GTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID-AFRPDLSSASFQRPQSETNVA 381

[Close]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Match: Q6DEG0 (TNF receptor-associated factor OS=Danio rerio OX=7955 GN=traf3 PE=2 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 1.010e-11
Identity = 56/230 (24.35%), Postives = 111/230 (48.26%), Query Frame = 1

Query:   10 LQQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQL-RVNKKLEIEKCDNDIRL------IQTFGNEIFIKFGFFEWQIDKISQQKRKEWI------YSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            L+QK+  M+     ++  + E   E++ L+   R++R E+ET  G++  +R  +  ++ +    +     +   +QQL R +  + +    +D+RL      +Q      F   G   W+I    ++K++  +      YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L+WPFK  VT+ + D G   K +   +   P+ + + +P+   N+ 
Sbjct:  314 LEQKLVSMQMLMSSHSEKLLEVEMELRELR-PLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSV----HDVRLAEMDLKLQVLETASF--NGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIA 536

[Close]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Match: A0A060WD36 (MATH domain-containing protein OS=Oncorhynchus mykiss OX=8022 GN=GSONMT00068560001 PE=4 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 4.476e-11
Identity = 56/195 (28.72%), Postives = 91/195 (46.67%), Query Frame = 1

Query:  109 RSLRSEMETNTGAINQIRMQIEKVE-----INFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            RS+R E+ET  G +  IR ++  +E      N    + E  Q+  H   L V+   EI   D D+R  Q      F   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G   K +   +   P  + + +P+   N+ 
Sbjct:    9 RSVREEVETLRGTVESIRSRVATLEGGRGGANPATHTLE-TQLSRHDDMLSVH---EIRLADMDLRF-QVLETASF--NGMLIWKIRDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLLWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTAEMNIA 196

[Close]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Match: A0A0P7UB07 (TNF receptor-associated factor 3-like (Fragment) OS=Scleropages formosus OX=113540 GN=Z043_109866 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.056e-10
Identity = 57/227 (25.11%), Postives = 107/227 (47.14%), Query Frame = 1

Query:   10 LQQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKL----EIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            ++QK+  M+     +   M E   E+++L    RS+R E+E+   ++  IR ++  +E+     S   + +   +QQ+  +  +    EI   D D+R  Q      +   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G   K +   +   P  + + +P+   N+ 
Sbjct:  261 VEQKLSSMQKVLSSHTEKMLEIELELRSL----RSMRDEVESLRNSVENIRSRVTALELGQVGTSSGTQTLKTLEQQMSRHDDMLSVHEIRLADMDLRF-QVLETASY--NGTLIWKIRDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPAGEMNIA 480

[Close]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Match: A0A1S3R8U3 (TNF receptor-associated factor OS=Salmo salar OX=8030 GN=LOC106600975 PE=3 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 2.152e-10
Identity = 56/195 (28.72%), Postives = 91/195 (46.67%), Query Frame = 1

Query:  109 RSLRSEMETNTGAINQIRMQIEKVE-----INFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            RS+R E+ET  G +  IR ++  +E      N    + E  Q+  H   L V+   EI   D D+R  Q      F   G   W+I    ++K++        +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G   K +   +   P  + + +P+   N+ 
Sbjct:  349 RSVREEVETLRGTVESIRSRVATLEGGRGGANPATHTLE-TQLSRHDDMLSVH---EIRLADMDLRF-QVLETASF--NGMLIWKICDYKRRKQEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTAEMNIA 536

[Close]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Match: S4RA88 (TNF receptor-associated factor OS=Petromyzon marinus OX=7757 PE=3 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.853e-10
Identity = 47/209 (22.49%), Postives = 104/209 (49.76%), Query Frame = 1

Query:   64 MEETNKEMKALKNEYRSLRSEMETNTGAINQ----IRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLA--INVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIK--YSDRPTDAGWMKPSNNTNVG 648
            + + N+++++L    R+   + + +T A+ +    +R ++  +E          ++ + H+Q+L ++  L ++  +  +++++T G       G   W+I   +++K      R   +YS+PFY+   GYKMC    +N        ++ + F +MRG++D  LEWPF+  VT+++ D G   + +   ++  P    + +P  + NV 
Sbjct:  183 LTQHNEQLQSLHVAQRA--PQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGL-LDTAERRLQVLETAGYS-----GKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVA 383

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261])

HSP 1 Score: 58.5362 bits (140), Expect = 1.139e-9
Identity = 56/223 (25.11%), Postives = 97/223 (43.50%), Query Frame = 1

Query:   10 LQQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            +QQKM  +E       R +E T   ++AL  + +  + ++E  +  + Q+   +   ++          Q+ E +Q LR     E++ C  D               G F W+I   S+++      R   ++S  FYS   GYKMCL +  N        ++ + F +MRGK+D  L+WPF   VT+ + D  N    I  + RP  +   + +P +  N+ 
Sbjct:  305 VQQKMTALENIVCVLNREVERTVLRLEALTRQQQLDQEKIENLSNKVRQLERTLTMRDL----------QLAESEQALR-----ELQFCTYD---------------GVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNREHIID-AFRPDISSTSFQRPISEMNIA 496

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 5.809e-9
Identity = 29/92 (31.52%), Postives = 49/92 (53.26%), Query Frame = 1

Query:  385 IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G   K +   +   P  + + +P+   N+ 
Sbjct:   28 LYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIA 119

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375])

HSP 1 Score: 54.299 bits (129), Expect = 3.301e-8
Identity = 35/116 (30.17%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I   S+++      R   ++S  FY+   GYKMCL I  N        ++ + F +MRG  D  L+WPF   VT+ + D  N    I  + RP  + + + +P ++ N+ 
Sbjct:  423 GVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID-AFRPDISSSSFQRPVSDMNIA 537

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Match: traf5 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:103031120])

HSP 1 Score: 53.9138 bits (128), Expect = 5.258e-8
Identity = 48/216 (22.22%), Postives = 89/216 (41.20%), Query Frame = 1

Query:   58 RNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVE-INFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFE------------WQIDKISQQKRK-EWIYSKPFYSESSGYKMCLAINVRXXXXXXXXXXXFH--LMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRPTDAG--WMKPSNNTNVGV 651
            R++EE  + + ++K E + LR  +E +          + K E ++ +   D  ++     Q LR +     + C +  RL+     ++      F+            W++    ++K     + S PFY+  SGYK+   + +          +  +  LMRG FD  L WPF+  VT+ V D       +  S  P  A   + +P++ TN  +
Sbjct:  306 RSVEEQRELVSSVKRELKDLRDVLEAD----------LTKEELVSLRASLDSLREQVAMTQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQRFQQLESTSYDGKLIWKVHDYHRKKEAGTALNSPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVSLSFTPDLASNNFRRPTSETNAAL 511

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325])

HSP 1 Score: 53.5286 bits (127), Expect = 5.528e-8
Identity = 27/114 (23.68%), Postives = 54/114 (47.37%), Query Frame = 1

Query:  331 GFFEWQIDKISQQKRKE------WIYSKPFYSESSGYKMCLAINVRXXXXXXXX---XXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSD-RPTDAGWMKPSNNTN 642
            G + W+++  S   R +       ++S PFY+   GYK+CL ++++            +  H M+G+FD +L WP +  + + V D   G   ++  + +P    + +P+   N
Sbjct:  375 GVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETKPDLQAFQRPTVQRN 488

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.4774 bits (171), Expect = 2.192e-14
Identity = 47/209 (22.49%), Postives = 104/209 (49.76%), Query Frame = 1

Query:   64 MEETNKEMKALKNEYRSLRSEMETNTGAINQ----IRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLA--INVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIK--YSDRPTDAGWMKPSNNTNVG 648
            + + N+++++L    R+   + + +T A+ +    +R ++  +E          ++ + H+Q+L ++  L ++  +  +++++T G       G   W+I   +++K      R   +YS+PFY+   GYKMC    +N        ++ + F +MRG++D  LEWPF+  VT+++ D G   + +   ++  P    + +P  + NV 
Sbjct:  183 LTQHNEQLQSLHVAQRA--PQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGL-LDTAERRLQVLETAGYS-----GKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVA 383

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 58.9214 bits (141), Expect = 1.749e-10
Identity = 31/116 (26.72%), Postives = 59/116 (50.86%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLA--INVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIK--YSDRPTDAGWMKPSNNTNVG 648
            G   W+I   +++K      R   +YS+PFY+   GY+MC    +N        ++ + F +MRG++D  L WPF+  VT+ + D G   + +   +   P  + + +P+++ N+ 
Sbjct:  325 GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIA 440

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27])

HSP 1 Score: 65.4698 bits (158), Expect = 2.580e-12
Identity = 41/115 (35.65%), Postives = 59/115 (51.30%), Query Frame = 1

Query:  331 GFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDR-PTDAGWMKPSNNTNVG 648
            G F W+IDK +++           IYS PFY+   GYK+C  L  N      D+Y+ I   LMRG++D  L WPF+  +TI + D  NG+   +  D  P    + +P+ N NV 
Sbjct:  380 GTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMNISETFDPDPCSISFQRPTRNINVA 494

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36])

HSP 1 Score: 57.3806 bits (137), Expect = 1.196e-9
Identity = 37/116 (31.90%), Postives = 59/116 (50.86%), Query Frame = 1

Query:  331 GFFEWQIDKISQQ------KRKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDR--PTDAGWMKPSNNTNVG 648
            G + W+ID+ +++       +   IYS PFY    GYK C  +  N        ++ + F LMRG+FD  L WPF+  VT  + D  + V  I  + R  PT + + +P++N N+ 
Sbjct:  378 GTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ-DRVHDIGDTFRPDPTSSSFKRPTSNMNIA 492

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4])

HSP 1 Score: 55.8398 bits (133), Expect = 3.302e-9
Identity = 42/185 (22.70%), Postives = 87/185 (47.03%), Query Frame = 1

Query:  145 AINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVN------KKLEIEKCDNDIRLIQ--TFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI-KYSDRPTDAGWMKPSNNTNVG 648
            A++++R ++ ++ +  Q+  D  +++   ++QL ++      + L I   +  +  +Q  TF + +        W+I  ++ ++      R    YS  F++   GYKMC  I  N      + ++ + F +MRG+FD  L WPF+  VT+ + D  N    I  +   P+ + + +P    N+ 
Sbjct:  273 AVDELRREVGRLNVKLQESDDIIRRL---ERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLL-------WKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDNVEHVIDAFRPDPSSSSFQRPRAEMNIA 447

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 53.9138 bits (128), Expect = 1.559e-8
Identity = 28/92 (30.43%), Postives = 46/92 (50.00%), Query Frame = 1

Query:  331 GFFEWQIDKISQQKRKE------WIYSKPFYSESSGYKMCLAINVRXXXXXXXXXXXF--HLMRGKFDYKLEWPFKYAVTINVTDTGNGVKT 582
            G F W++D   Q +          I+S PFY+   GYKMCL +N+          +    H+M+G +D  LEWPF   +T+++ D  + + +
Sbjct:  332 GTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDS 423

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Match: EDO29145 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4G8])

HSP 1 Score: 44.669 bits (104), Expect = 1.886e-6
Identity = 29/87 (33.33%), Postives = 46/87 (52.87%), Query Frame = 1

Query:  310 NEIFI-KFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLA--INVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTD 561
            N IF+ K   ++ Q D+      +  I+S PFY+   GYK+ L   +N RD     ++ +   +M+G +D  LEWPFK  +T  + D
Sbjct:    1 NGIFLWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRLKAYLNGRDRGKGTHLSLYIIIMKGDYDALLEWPFKQKITFYLID 87

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601])

HSP 1 Score: 68.5514 bits (166), Expect = 5.467e-13
Identity = 52/192 (27.08%), Postives = 91/192 (47.40%), Query Frame = 1

Query:  109 RSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIR--LIQTFGNEIFIKFGFFEWQIDKISQQKRKEW------IYSKPFYSESSGYKMC--LAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTI--KYSDRPTDAGWMKPSNNTNVG 648
            R LR EME+  G ++ +R ++  +E   +   +   Q+  H   L V+   EI   D D+R  +++T         G   W+I    ++K+         +YS+PFY+   GYKMC  + +N        ++ + F +MRG++D  L WPFK  VT+ + D G   K +   +   P+ + + +P    N+ 
Sbjct:  232 RQLRDEMESLRGTLDTVRTRLSALEQGGRASLE--TQLNRHDDMLSVH---EIRLADMDLRFQVLETASYN-----GTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIA 413

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 58.5362 bits (140), Expect = 1.167e-9
Identity = 56/207 (27.05%), Postives = 100/207 (48.31%), Query Frame = 1

Query:   70 ETNKEMKALKNEYRSLRSEMETNTGAI----NQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            + +K++ AL+N    L  E+E ++  +    +Q R+  EK+E      S++ +Q+   ++ L V K L++ + +  +R +Q    +     G F W+I   S ++      R   ++S  FYS   GYKMCL +  N        ++ + F +MR K+D  L+WPF   VT+ + D  N    I  + RP  T   + +P +  N+ 
Sbjct:  296 DLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIE----NLSNKIRQL---ERSLTV-KDLQLSEAEQMVRELQYCTYD-----GIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIID-AFRPDITSTSFQRPVSEMNIA 488

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 58.5362 bits (140), Expect = 1.239e-9
Identity = 56/207 (27.05%), Postives = 100/207 (48.31%), Query Frame = 1

Query:   70 ETNKEMKALKNEYRSLRSEMETNTGAI----NQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            + +K++ AL+N    L  E+E ++  +    +Q R+  EK+E      S++ +Q+   ++ L V K L++ + +  +R +Q    +     G F W+I   S ++      R   ++S  FYS   GYKMCL +  N        ++ + F +MR K+D  L+WPF   VT+ + D  N    I  + RP  T   + +P +  N+ 
Sbjct:  289 DLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIE----NLSNKIRQL---ERSLTV-KDLQLSEAEQMVRELQYCTYD-----GIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIID-AFRPDITSTSFQRPVSEMNIA 481

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626])

HSP 1 Score: 53.5286 bits (127), Expect = 6.970e-8
Identity = 34/116 (29.31%), Postives = 57/116 (49.14%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I   ++++      R   ++S  FY+   GYKMCL I  N        ++ + F +MRG  D  L+WPF   VT+ + D  N    I  + RP  + + + +P ++ N+ 
Sbjct:  420 GIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNNREHIID-AFRPDISSSSFQRPVSDMNIA 534

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Match: unm_sa808 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101155367])

HSP 1 Score: 51.9878 bits (123), Expect = 2.114e-7
Identity = 35/116 (30.17%), Postives = 56/116 (48.28%), Query Frame = 1

Query:  331 GFFEWQIDKISQQK------RKEWIYSKPFYSESSGYKMCLAI--NVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRP--TDAGWMKPSNNTNVG 648
            G F W+I   ++++      R   ++S  FY+   GYKMCL I  N        ++ + F +MRG  D  L+WPF   VT+ + D  N    I  + RP  T + + +P +  N+ 
Sbjct:  447 GVFIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQSNREHIID-AFRPDVTSSSFQRPVSEMNIA 561

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Match: SMESG000049895.1 (SMESG000049895.1)

HSP 1 Score: 375.17 bits (962), Expect = 1.093e-129
Identity = 194/219 (88.58%), Postives = 202/219 (92.24%), Query Frame = 1

Query:   13 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGN----GVKTIKYSDRPTDAGWMKPSNNTNVGVQV 657
            QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMRGKFDYKLEWPFKY VT++  D+ N      K+IKYSD P  AGW KPSN+ N  +++
Sbjct:  224 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMRGKFDYKLEWPFKYTVTVDAVDSANRNLICSKSIKYSDYPYLAGWRKPSNDRNNPIRI 442

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Match: SMESG000049895.1 (SMESG000049895.1)

HSP 1 Score: 374.015 bits (959), Expect = 3.056e-129
Identity = 194/219 (88.58%), Postives = 202/219 (92.24%), Query Frame = 1

Query:   13 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGN----GVKTIKYSDRPTDAGWMKPSNNTNVGVQV 657
            QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMRGKFDYKLEWPFKY VT++  D+ N      K+IKYSD P  AGW KPSN+ N  +++
Sbjct:  231 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMRGKFDYKLEWPFKYTVTVDAVDSANRNLICSKSIKYSDYPYLAGWRKPSNDRNNPIRI 449

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Match: SMESG000049895.1 (SMESG000049895.1)

HSP 1 Score: 330.102 bits (845), Expect = 2.890e-112
Identity = 179/219 (81.74%), Postives = 187/219 (85.39%), Query Frame = 1

Query:   13 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRXXXXXXXXXXXFHLMRGKFDYKLEWPFKYAVTINVTDTGN----GVKTIKYSDRPTDAGWMKPSNNTNVGVQV 657
            QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMR                ++  D+ N      K+IKYSD P  AGW KPSN+ N  +++
Sbjct:  224 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDYIDIDFHLMR----------------VDAVDSANRNLICSKSIKYSDYPYLAGWRKPSNDRNNPIRI 426

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Match: SMESG000049895.1 (SMESG000049895.1)

HSP 1 Score: 295.434 bits (755), Expect = 8.870e-100
Identity = 144/144 (100.00%), Postives = 144/144 (100.00%), Query Frame = 1

Query:   13 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN 444
            QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN
Sbjct:  224 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN 367

[Close]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Match: SMESG000049895.1 (SMESG000049895.1)

HSP 1 Score: 294.664 bits (753), Expect = 2.447e-99
Identity = 144/144 (100.00%), Postives = 144/144 (100.00%), Query Frame = 1

Query:   13 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN 444
            QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN
Sbjct:  231 QQKMCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQIEKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIFIKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAIN 374

The following BLAST results are available for this feature:

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Celegans
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Fly
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Sea Lamprey
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Yeast
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRAF3	3.132e-11	24.55	TNF receptor associated factor 3 [Source:HGNC Symb...	[more]
TRAF3	4.080e-11	24.55	TNF receptor associated factor 3 [Source:HGNC Symb...	[more]
TRAF3	4.080e-11	24.55	TNF receptor associated factor 3 [Source:HGNC Symb...	[more]
TRAF3	4.231e-11	24.55	TNF receptor associated factor 3 [Source:HGNC Symb...	[more]
TRAF3	4.231e-11	24.55	TNF receptor associated factor 3 [Source:HGNC Symb...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
trf-1	4.376e-6	34.57	TNF Receptor Associated Factor (TRAF) homolog; TRF...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
traf3	4.516e-15	24.35	TNF receptor-associated factor 3 [Source:ZFIN;Acc:...	[more]
BX901915.1	1.424e-8	30.17	pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:2...	[more]
AL844899.1	1.424e-8	30.17	pep chromosome:GRCz11:CHR_ALT_CTG5_2_4:28756846:28...	[more]
traf2b	1.797e-8	23.67	Tnf receptor-associated factor 2b [Source:ZFIN;Acc...	[more]
traf2b	1.797e-8	23.67	Tnf receptor-associated factor 2b [Source:ZFIN;Acc...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ssh2	1.062e-11	25.53	slingshot protein phosphatase 2 [Source:Xenbase;Ac...	[more]
ssh2	1.292e-11	25.53	slingshot protein phosphatase 2 [Source:Xenbase;Ac...	[more]
hspb6	7.786e-9	31.90	heat shock protein family B (small) member 6 [Sour...	[more]
TRAF2	8.793e-7	29.31	TNF receptor associated factor 2 [Source:NCBI gene...	[more]
TRAF2	1.103e-6	29.31	TNF receptor associated factor 2 [Source:NCBI gene...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Traf3	4.542e-11	24.55	TNF receptor-associated factor 3 [Source:MGI Symbo...	[more]
Traf3	4.547e-11	24.55	TNF receptor-associated factor 3 [Source:MGI Symbo...	[more]
Traf3	4.547e-11	24.55	TNF receptor-associated factor 3 [Source:MGI Symbo...	[more]
Traf1	1.765e-8	22.17	TNF receptor-associated factor 1 [Source:MGI Symbo...	[more]
Traf1	1.765e-8	22.17	TNF receptor-associated factor 1 [Source:MGI Symbo...	[more]

BLAST of TNF receptor-associated factor 1-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q13114\|TRAF3_HUMAN	2.032e-10	24.55	TNF receptor-associated factor 3 OS=Homo sapiens O...	[more]
sp\|Q60803\|TRAF3_MOUSE	3.177e-10	24.55	TNF receptor-associated factor 3 OS=Mus musculus O...	[more]
sp\|P39428\|TRAF1_MOUSE	1.234e-7	22.17	TNF receptor-associated factor 1 OS=Mus musculus O...	[more]
sp\|Q6IWL4\|TRAF6_DANRE	4.368e-7	24.55	TNF receptor-associated factor 6 OS=Danio rerio OX...	[more]
sp\|Q13077\|TRAF1_HUMAN	4.547e-7	23.90	TNF receptor-associated factor 1 OS=Homo sapiens O...	[more]

BLAST of TNF receptor-associated factor 1-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q6DEG0	1.010e-11	24.35	TNF receptor-associated factor OS=Danio rerio OX=7...	[more]
A0A060WD36	4.476e-11	28.72	MATH domain-containing protein OS=Oncorhynchus myk...	[more]
A0A0P7UB07	1.056e-10	25.11	TNF receptor-associated factor 3-like (Fragment) O...	[more]
A0A1S3R8U3	2.152e-10	28.72	TNF receptor-associated factor OS=Salmo salar OX=8...	[more]
S4RA88	2.853e-10	22.49	TNF receptor-associated factor OS=Petromyzon marin...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
traf2b	1.139e-9	25.11	TNF receptor associated factor 2 [Source:NCBI gene...	[more]
ENSAMXT00000035169.1	5.809e-9	31.52	pep primary_assembly:Astyanax_mexicanus-2.0:9:3354...	[more]
traf2a	3.301e-8	30.17	TNF receptor-associated factor 2-like [Source:NCBI...	[more]
traf5	5.258e-8	22.22	TNF receptor-associated factor 5 [Source:NCBI gene...	[more]
traf6	5.528e-8	23.68	TNF receptor associated factor 6 [Source:NCBI gene...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ENSPMAT00000002130.1	2.192e-14	22.49	pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 g...	[more]
ENSPMAT00000000074.1	1.749e-10	26.72	pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO35237	2.580e-12	35.65	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49464	1.196e-9	31.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38873	3.302e-9	22.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48773	1.559e-8	30.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29145	1.886e-6	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
traf3	5.467e-13	27.08	TNF receptor associated factor 3 [Source:NCBI gene...	[more]
traf2b	1.167e-9	27.05	TNF receptor associated factor 2 [Source:NCBI gene...	[more]
traf2b	1.239e-9	27.05	TNF receptor associated factor 2 [Source:NCBI gene...	[more]
ENSORLT00000020861.2	6.970e-8	29.31	TNF receptor-associated factor 2 [Source:NCBI gene...	[more]
unm_sa808	2.114e-7	30.17	TNF receptor-associated factor 2 [Source:NCBI gene...	[more]

BLAST of TNF receptor-associated factor 1-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000049895.1	1.093e-129	88.58	SMESG000049895.1	[more]
SMESG000049895.1	3.056e-129	88.58	SMESG000049895.1	[more]
SMESG000049895.1	2.890e-112	81.74	SMESG000049895.1	[more]
SMESG000049895.1	8.870e-100	100.00	SMESG000049895.1	[more]
SMESG000049895.1	2.447e-99	100.00	SMESG000049895.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001022 ID=SMED30001022|Name=TNF receptor-associated factor 1-like|organism=Schmidtea mediterranea sexual|type=transcript|length=730bp
TATTTGTGATTGCAGCAGAAAATGTGTGAGATGGAAGCGAAAGAACTGGA
AAACGCCAGGAATATGGAGGAAACAAATAAAGAAATGAAGGCATTAAAAA
ATGAGTATCGATCATTGAGAAGCGAAATGGAGACAAATACTGGAGCAATC
AATCAAATCCGGATGCAGATCGAGAAGGTTGAGATAAATTTCCAAAAGCA
AAGTGATGAATTTAAACAAATATATGAGCATCAGCAGCAGTTACGAGTCA
ATAAAAAACTGGAAATAGAGAAATGTGACAATGACATTCGGCTTATTCAA
ACATTTGGAAATGAAATTTTTATAAAATTTGGATTTTTTGAATGGCAAAT
TGATAAAATTTCACAGCAAAAGAGAAAGGAATGGATATACAGCAAGCCAT
TTTATTCTGAGTCATCCGGGTACAAAATGTGTTTGGCGATTAATGTTAGG
GATTATTATATTGATGATTATATTGATATTGATTTCCATTTGATGCGTGG
TAAATTCGATTATAAATTGGAATGGCCATTTAAATATGCAGTAACAATTA
ATGTGACCGATACAGGAAATGGAGTTAAAACAATAAAATATTCTGATAGA
CCTACTGATGCCGGATGGATGAAACCATCAAATAATACAAATGTTGGAGT
TCAAGTTATCATTGGCTTGATATTCAATTAGATTCACAAGCAATAAAAAA
TGATCAGCTGCTGATGAAATGCAGAGTGGA

protein sequence of SMED30001022-orf-1

>SMED30001022-orf-1 ID=SMED30001022-orf-1|Name=SMED30001022-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=220bp
MCEMEAKELENARNMEETNKEMKALKNEYRSLRSEMETNTGAINQIRMQI
EKVEINFQKQSDEFKQIYEHQQQLRVNKKLEIEKCDNDIRLIQTFGNEIF
IKFGFFEWQIDKISQQKRKEWIYSKPFYSESSGYKMCLAINVRDYYIDDY
IDIDFHLMRGKFDYKLEWPFKYAVTINVTDTGNGVKTIKYSDRPTDAGWM
KPSNNTNVGVQVIIGLIFN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0005164	tumor necrosis factor receptor binding
GO:0005515	protein binding
GO:0004842	ubiquitin-protein transferase activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000101	muscle cell
PLANA:0000142	posterior region of the whole animal

Vocabulary: **INTERPRO**
Term	Definition
IPR043211	TNF_rcpt-assoc_TRAF
IPR008974	TRAF-like

Vocabulary: **biological process**
Term	Definition
GO:0001817	regulation of cytokine production
GO:0001878	response to yeast
GO:0007165	signal transduction
GO:0008063	Toll signaling pathway
GO:0016567	protein ubiquitination
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0042981	regulation of apoptotic process
GO:0045087	innate immune response
GO:0050688	regulation of defense response to virus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 8..63
None	No IPR available	PANTHER	PTHR10131:SF129	TNF RECEPTOR-ASSOCIATED FACTOR 6	coord: 2..168
IPR008974	TRAF-like	GENE3D	G3DSA:2.60.210.10		coord: 60..168 e-value: 7.4E-15 score: 56.8
IPR008974	TRAF-like	SUPERFAMILY	SSF49599	TRAF domain-like	coord: 104..168
IPR043211	TNF receptor-associated factor TRAF	PANTHER	PTHR10131	TNF RECEPTOR ASSOCIATED FACTOR	coord: 2..168

Main menu

TNF receptor-associated factor 1-like

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner