Innexin

Overview


Name	Innexin
Smed ID	SMED30001004
Length (bp)	507

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30001004

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
head region	SMED30001004	SMESG000031896.1 SMESG000031895.1	OX_Smed_1.0.14398	ox_Smed_v2	PMID:24238224 Kao et al., 2013
Category 2 cell	SMED30001004	SMESG000031896.1 SMESG000031895.1	dd_Smed_v4_15239_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 50.447 bits (119), Expect = 1.241e-7
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:   19 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 162

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 50.0618 bits (118), Expect = 1.580e-7
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:   80 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 223

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 50.0618 bits (118), Expect = 1.587e-7
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:   71 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 214

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 50.0618 bits (118), Expect = 1.593e-7
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:   80 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 223

[Close]

BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 50.0618 bits (118), Expect = 1.683e-7
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:   93 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 236

[Close]

BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 49.6766 bits (117), Expect = 3.329e-6
Identity = 38/145 (26.21%), Postives = 69/145 (47.59%), Query Frame = 1

Query:   64 EDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPA---TEQXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSI 489
            +DF DK N+++T  +L    L+V+ KQYV  PI C++                CW+Q T  +     IP    + +  +I   + +  +L++ +  F    ++W+ L Y H+G ++Q LV  A  A     E + + V  +A+ +
Sbjct:  139 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDAMEQYTENY-CWVQNTYWVPMQEDIPREIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHM 282

[Close]

BLAST of Innexin vs. TrEMBL
Match: A0A430QT10 (Innexin OS=Schistosoma bovis OX=6184 GN=inx PE=3 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 3.015e-49
Identity = 96/175 (54.86%), Postives = 131/175 (74.86%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATEQXXXXXXXXXXRN------LLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            M+  EFLD+LSKFQV  Y G+EDFADKFNF  TV+VL+L T +VT+KQY++KPISCYM+TD+GG NLL+Y+ENYCW+QGT+PI+Y+G++P T++    LE+ K+        +L +    F    LIWQ++CYN  GTD+ HLV  ANQAVH+++E R KMV +LAK++ Q  +Q
Sbjct:    1 MIGTEFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTIKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVHHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQ 175

[Close]

BLAST of Innexin vs. TrEMBL
Match: A0A183JFJ2 (Innexin OS=Schistosoma curassoni OX=6186 GN=inx PE=3 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 4.579e-49
Identity = 96/175 (54.86%), Postives = 131/175 (74.86%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATEQXXXXXXXXXXRN------LLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            M+  EFLD+LSKFQV  Y G+EDFADKFNF  TV+VL+L T +VT+KQY++KPISCYM+TD+GG NLL+Y+ENYCW+QGT+PI+Y+G++P T++    LE+ K+        +L +    F    LIWQ++CYN  GTD+ HLV  ANQAVH+++E R KMV +LAK++ Q  +Q
Sbjct:    1 MIGTEFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTIKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVHHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQ 175

[Close]

BLAST of Innexin vs. TrEMBL
Match: A0A4S2LNY2 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 6.009e-47
Identity = 98/175 (56.00%), Postives = 130/175 (74.29%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPAT----EQXXXXXXXXXXRNLLSMGSFCFGFAI--LIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            MV  EFLD++SKFQV  Y G+EDFADKFNF  TV++LLL T VVTVKQY++KPISCYM+TD+GG NLL+Y+ENYCW+QGTIPI+Y GK+P T    E+  +            +G  C  F +  +IWQ++CYN TGTDIQHLV SANQAVH++++ R KM+ ++A+++ Q  +Q
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLITVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQ 175

[Close]

BLAST of Innexin vs. TrEMBL
Match: G7YJJ0 (Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=3 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 7.587e-47
Identity = 98/175 (56.00%), Postives = 130/175 (74.29%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPAT----EQXXXXXXXXXXRNLLSMGSFCFGFAI--LIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            MV  EFLD++SKFQV  Y G+EDFADKFNF  TV++LLL T VVTVKQY++KPISCYM+TD+GG NLL+Y+ENYCW+QGTIPI+Y GK+P T    E+  +            +G  C  F +  +IWQ++CYN TGTDIQHLV SANQAVH++++ R KM+ ++A+++ Q  +Q
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLVTVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQ 175

[Close]

BLAST of Innexin vs. TrEMBL
Match: A0A419PWC8 (Innexin OS=Clonorchis sinensis OX=79923 GN=unc-9 PE=3 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 4.519e-46
Identity = 98/175 (56.00%), Postives = 130/175 (74.29%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPAT----EQXXXXXXXXXXRNLLSMGSFCFGFAI--LIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            MV  EFLD++SKFQV  Y G+EDFADKFNF  TV++LLL T VVTVKQY++KPISCYM+TD+GG NLL+Y+ENYCW+QGTIPI+Y GK+P T    E+  +            +G  C  F +  +IWQ++CYN TGTDIQHLV SANQAVH++++ R KM+ ++A+++ Q  +Q
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLVTVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQ 175

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000069482.1 (SMESG000069482.1)

HSP 1 Score: 175.252 bits (443), Expect = 6.776e-56
Identity = 104/175 (59.43%), Postives = 129/175 (73.71%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATE------QXXXXXXXXXXRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            MVA EFLD +SKFQ+TNY G+EDFADKFNF  T IV  +   VV+VK YVLKPISCY++ D  G NLLNY+ENYCW+QGT+PI Y+GKIP  +      Q+ +IL  + +  +LS+    F    +IWQ+ CYN TGTDIQHL+TSAN AVHSSEEAR KMV++LAKS+ Q  +Q
Sbjct:    1 MVAQEFLDQISKFQITNYVGVEDFADKFNFLLTTIVFSICASVVSVKLYVLKPISCYLAVDSSGTNLLNYVENYCWVQGTVPIKYDGKIPTNDAEWNQLQKNKILYYQWVPFVLSLQCIMFYIPRIIWQMFCYNRTGTDIQHLITSANHAVHSSEEARKKMVIHLAKSLEQLLFQ 175

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1)

HSP 1 Score: 158.688 bits (400), Expect = 7.191e-47
Identity = 97/175 (55.43%), Postives = 128/175 (73.14%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATEQXXXXXXXXXXRN------LLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            MVA EFLD+LSK QV+   G+ED  D+ NF F+VIVL++  L+VTVKQYV KPISCY+  ++GG NLL+Y+EN CW+QGTI +S   K P+T++E + LE+ K+        +L +    F    L+WQ++CYN TGTDIQHLV SANQAVHSS+EAR+KMV YL+K++ Q  YQ
Sbjct:    1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEKHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQ 175

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000031895.1 (SMESG000031895.1)

HSP 1 Score: 146.362 bits (368), Expect = 7.079e-46
Identity = 94/94 (100.00%), Postives = 94/94 (100.00%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATEQ 282
            MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFTVIVLLLSTLVVTVKQYVLKPISCYMSTDVGGLNLLNYLENYCWIQGTIPISYNGKIPATEQ
Sbjct:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFTVIVLLLSTLVVTVKQYVLKPISCYMSTDVGGLNLLNYLENYCWIQGTIPISYNGKIPATEQ 94

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070496.1 (SMESG000070496.1)

HSP 1 Score: 146.362 bits (368), Expect = 7.454e-42
Identity = 101/209 (48.33%), Postives = 126/209 (60.29%), Query Frame = 1

Query:    1 MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFXXXXXXXXXXXXXXKQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATE------------------------------QXXXXXXXXXXRN---------LLSMGS-FCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            M A +F D L+KFQ   Y G++D ADK NF  TVI+LL+   VVTV+QYVLKPISCY+STD+GG+NLL+Y+EN+CW+ GTIPISYNG  P TE                              +   I   K I+N         L S+ S F F    L+W L+C N TGTDIQH++TSANQAVHS EEA+ KM +Y+AK+I    YQ
Sbjct:    1 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILMWKTRVICEARAIWKPQTKIRLIFWLKSIKNSFYIINGCHLFSVFSAFLFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQ 209

[Close]

BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070656.1 (SMESG000070656.1)

HSP 1 Score: 130.568 bits (327), Expect = 1.702e-36
Identity = 78/129 (60.47%), Postives = 95/129 (73.64%), Query Frame = 1

Query:  139 KQYVLKPISCYMSTDVGGXXXXXXXXXXCWIQGTIPISYNGKIPATEQXXXXXXXXXXRN------LLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEEARNKMVLYLAKSIAQTCYQ 507
            KQY+LKPISCY+ST + G NLL Y+ENYCW++GTIPISY+GKIP+T +E   L + KI        LLS+ +  F    LIWQ+ CYN TGTDI HL+ SANQAVHSS+EAR KMV Y+AK+I Q  YQ
Sbjct:    2 KQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQ 129

The following BLAST results are available for this feature:

BLAST of Innexin vs. Ensembl Human
BLAST of Innexin vs. Ensembl Celegans
BLAST of Innexin vs. Ensembl Fly
BLAST of Innexin vs. Ensembl Zebrafish
BLAST of Innexin vs. Ensembl Xenopus
BLAST of Innexin vs. Ensembl Mouse
BLAST of Innexin vs. UniProt/SwissProt
BLAST of Innexin vs. TrEMBL
BLAST of Innexin vs. Ensembl Cavefish
BLAST of Innexin vs. Ensembl Sea Lamprey
BLAST of Innexin vs. Ensembl Yeast
BLAST of Innexin vs. Ensembl Nematostella
BLAST of Innexin vs. Ensembl Medaka
BLAST of Innexin vs. Planmine SMEST

BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
unc-7	1.241e-7	26.21	Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]
unc-7	1.580e-7	26.21	Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]
unc-7	1.587e-7	26.21	Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]
unc-7	1.593e-7	26.21	Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]
unc-7	1.683e-7	26.21	Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0...	[more]

BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1


Match Name	E-value	Identity	Description
sp\|Q03412\|UNC7_CAEEL	3.329e-6	26.21	Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN...	[more]

BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A430QT10	3.015e-49	54.86	Innexin OS=Schistosoma bovis OX=6184 GN=inx PE=3 S...	[more]
A0A183JFJ2	4.579e-49	54.86	Innexin OS=Schistosoma curassoni OX=6186 GN=inx PE...	[more]
A0A4S2LNY2	6.009e-47	56.00	Innexin OS=Opisthorchis felineus OX=147828 GN=inx ...	[more]
G7YJJ0	7.587e-47	56.00	Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=...	[more]
A0A419PWC8	4.519e-46	56.00	Innexin OS=Clonorchis sinensis OX=79923 GN=unc-9 P...	[more]

BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000069482.1	6.776e-56	59.43	SMESG000069482.1	[more]
SMESG000065083.1	7.191e-47	55.43	SMESG000065083.1	[more]
SMESG000031895.1	7.079e-46	100.00	SMESG000031895.1	[more]
SMESG000070496.1	7.454e-42	48.33	SMESG000070496.1	[more]
SMESG000070656.1	1.702e-36	60.47	SMESG000070656.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30001004 ID=SMED30001004|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=507bp
ATGGTTGCCCTTGAATTTCTGGACTTCCTCAGTAAGTTCCAAGTAACAAA
TTATGCTGGAATAGAGGATTTTGCGGATAAATTTAATTTCCATTTCACTG
TCATCGTTTTGTTGTTGTCTACCCTTGTTGTTACAGTGAAACAATATGTA
TTGAAACCGATCTCATGCTACATGTCGACAGATGTCGGAGGATTAAATTT
GCTGAACTATTTGGAGAACTATTGCTGGATCCAAGGAACGATACCAATAT
CATACAATGGGAAAATTCCAGCGACTGAACAGGAGTTGGAAATTTTAGAA
GAAAAAAAAATACGCAATTTATTATCAATGGGTTCCTTTTGCTTTGGGTT
TGCAATACTGATTTGGCAACTTTTATGTTATAACCACACAGGAACCGACA
TTCAGCATCTTGTCACAAGTGCCAACCAAGCGGTTCACTCAAGTGAAGAG
GCTAGGAACAAAATGGTCCTTTATTTAGCAAAATCAATAGCCCAAACATG
TTATCAA

protein sequence of SMED30001004-orf-1

>SMED30001004-orf-1 ID=SMED30001004-orf-1|Name=SMED30001004-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=169bp
MVALEFLDFLSKFQVTNYAGIEDFADKFNFHFTVIVLLLSTLVVTVKQYV
LKPISCYMSTDVGGLNLLNYLENYCWIQGTIPISYNGKIPATEQELEILE
EKKIRNLLSMGSFCFGFAILIWQLLCYNHTGTDIQHLVTSANQAVHSSEE
ARNKMVLYLAKSIAQTCYQ

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000028	Category 2 cell
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR000990	Innexin

Vocabulary: **cellular component**
Term	Definition
GO:0005921	gap junction
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction

Vocabulary: **biological process**
Term	Definition
GO:0006810	transport
GO:0006811	ion transport

Main menu

Innexin

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Owlery

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