Thioredoxin

Overview
NameThioredoxin
Smed IDSMED30000901
Length (bp)508
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Thioredoxin (SMED30000901) t-SNE clustered cells

Violin plots show distribution of expression levels for Thioredoxin (SMED30000901) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Thioredoxin (SMED30000901) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Thioredoxin (SMED30000901) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30000901

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v4_89_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v6_89_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
GABAergic neuronSMED30000901SMESG000069662.1 SMESG000030342.1 dd_Smed_v6_89_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXN (thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435])

HSP 1 Score: 85.5001 bits (210), Expect = 1.345e-21
Identity = 49/103 (47.57%), Postives = 74/103 (71.84%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELL-ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            MV+++ + T F E L A+ DKL+VVDF+ATWCGPC+ I P F++LS+++ +V+F++VDVD   D A +C+V  MPTF F+K      +FSGA+++KL   I +
Sbjct:    1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINE 103
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXN (thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435])

HSP 1 Score: 75.485 bits (184), Expect = 5.995e-18
Identity = 40/103 (38.83%), Postives = 58/103 (56.31%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELL-ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            MV+++ + T F E L A+ DKL+VVDF+ATWCGPC+ I P F+ ++ E                    C+V  MPTF F+K      +FSGA+++KL   I +
Sbjct:    1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHDVASE--------------------CEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINE 83
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXNL1 (thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436])

HSP 1 Score: 57.7658 bits (138), Expect = 6.262e-10
Identity = 33/88 (37.50%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT   CGPC +IAP F+++S ++P  VF++VDV +   TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXNL1 (thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436])

HSP 1 Score: 57.7658 bits (138), Expect = 6.262e-10
Identity = 33/88 (37.50%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT   CGPC +IAP F+++S ++P  VF++VDV +   TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Human
Match: TXNL1 (thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436])

HSP 1 Score: 57.7658 bits (138), Expect = 6.386e-10
Identity = 33/88 (37.50%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT   CGPC +IAP F+++S ++P  VF++VDV +   TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   12 ELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKI 99
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: trx-1 (Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09433])

HSP 1 Score: 62.7734 bits (151), Expect = 3.799e-13
Identity = 39/103 (37.86%), Postives = 63/103 (61.17%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            + EL  +++F++L+    +K+I++DF ATWCGPC+ IAP++  L+     ++F KVDVD+  D   K  V  MPTF F K+        G  ED+LR+ + ++
Sbjct:    8 ILELADMSDFEQLIRQHPEKIIILDFYATWCGPCKAIAPLYKELATTHKGIIFCKVDVDEAEDLCSKYDVKMMPTFIFTKNGDAIEALEGCVEDELRQKVLEH 110
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: Y55F3AR.2 (pep chromosome:WBcel235:IV:1094545:1096723:1 gene:WBGene00021933.1 transcript:Y55F3AR.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y55F3AR.2)

HSP 1 Score: 64.3142 bits (155), Expect = 9.373e-13
Identity = 40/94 (42.55%), Postives = 56/94 (59.57%), Query Frame = 3 
Query:  111 TEFD-ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAIT 389
            ++FD +  A   K + VDFTA+WCGPCQ IAP+F+ L+ ++   VF+KVDVD+   TA    V +MPTF  + +   K    GA E  LR  + 
Sbjct:   10 SDFDRKFSAGNGKAVFVDFTASWCGPCQYIAPIFSDLANQYKGSVFLKVDVDECRGTAATYGVNAMPTFIAFVNGQKKATIQGADESGLRSMVA 103
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: trx-1 (Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09433])

HSP 1 Score: 58.5362 bits (140), Expect = 1.326e-11
Identity = 37/96 (38.54%), Postives = 59/96 (61.46%), Query Frame = 3 
Query:  111 TEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            ++F++L+    +K+I++DF ATWCGPC+ IAP++  L+     ++F KVDVD+  D   K  V  MPTF F K+        G  ED+LR+ + ++
Sbjct:   16 SDFEQLIRQHPEKIIILDFYATWCGPCKAIAPLYKELATTHKGIIFCKVDVDEAEDLCSKYDVKMMPTFIFTKNGDAIEALEGCVEDELRQKVLEH 111
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: png-1 (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase [Source:UniProtKB/Swiss-Prot;Acc:Q9TW67])

HSP 1 Score: 60.8474 bits (146), Expect = 3.006e-11
Identity = 34/101 (33.66%), Postives = 59/101 (58.42%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLASCD--KLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            V E+ ++ E + +L   D  +LI++DF A WCGPC+ I+P+F   S E+ +  F+KV+ D   D  ++  +++MPTF F K+        GA++  + + I
Sbjct:    3 VTEVGSLPELNNILERSDANRLIIIDFFANWCGPCRMISPIFEQFSAEYGNATFLKVNCDVARDIVQRYNISAMPTFIFLKNRQQVDMVRGANQQAIAEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Celegans
Match: txl-1 (ThioredoXin-Like; Thioredoxin-like protein; Thioredoxin-like protein TXL [Source:UniProtKB/TrEMBL;Acc:G5EES9])

HSP 1 Score: 59.3066 bits (142), Expect = 6.439e-11
Identity = 34/81 (41.98%), Postives = 46/81 (56.79%), Query Frame = 3 
Query:  144 KLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            K ++VDFTA WCGPC+ IAP F  LS ++   VF+KVDV+    T+ +  V SMPTF  ++      Q  GA    L   +
Sbjct:   22 KSVIVDFTAVWCGPCKMIAPTFEALSNQYLGAVFLKVDVEICEKTSSENGVNSMPTFMVFQSGVRVEQMKGADAKALETMV 102
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: Txl (gene:FBgn0035631 transcript:FBtr0077098)

HSP 1 Score: 71.633 bits (174), Expect = 3.518e-15
Identity = 42/91 (46.15%), Postives = 61/91 (67.03%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            EL  +  +L+VVDFTA+WCGPC++IAP+F T   ++P  +F+KVDVDK  DTA    V++MPTF FY++ T   +  GA  + L   I ++
Sbjct:   15 ELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQEH 105
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: dhd (gene:FBgn0011761 transcript:FBtr0070749)

HSP 1 Score: 63.929 bits (154), Expect = 1.428e-13
Identity = 33/82 (40.24%), Postives = 47/82 (57.32%), Query Frame = 3 
Query:  132 ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXX-XXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKL 374
            A+ DKLIV+DF ATWCGPC+++     +L++++     V         +  E+ KV SMPTF F + N     F+GA E KL
Sbjct:   16 AADDKLIVLDFYATWCGPCKEMESTVKSLARKYSSKAVVLKIDVDKFEELTERYKVRSMPTFVFLRQNRRLASFAGADEHKL 97
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: dhd (gene:FBgn0011761 transcript:FBtr0345745)

HSP 1 Score: 63.929 bits (154), Expect = 1.428e-13
Identity = 33/82 (40.24%), Postives = 47/82 (57.32%), Query Frame = 3 
Query:  132 ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXX-XXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKL 374
            A+ DKLIV+DF ATWCGPC+++     +L++++     V         +  E+ KV SMPTF F + N     F+GA E KL
Sbjct:   16 AADDKLIVLDFYATWCGPCKEMESTVKSLARKYSSKAVVLKIDVDKFEELTERYKVRSMPTFVFLRQNRRLASFAGADEHKL 97
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: TrxT (gene:FBgn0029752 transcript:FBtr0070755)

HSP 1 Score: 62.3882 bits (150), Expect = 1.555e-12
Identity = 40/87 (45.98%), Postives = 55/87 (63.22%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXX-XXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRK 380
            +L+ + DKL+V+DF A WCGPC+ IAP  + L+Q++ D V V  V+VD+N D   +  V SMPTF F K   +   F G + DKL K
Sbjct:   14 QLILAEDKLVVIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAK 100
[Close]
BLAST of Thioredoxin vs. Ensembl Fly
Match: TrxT (gene:FBgn0029752 transcript:FBtr0340478)

HSP 1 Score: 62.3882 bits (150), Expect = 1.555e-12
Identity = 40/87 (45.98%), Postives = 55/87 (63.22%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXX-XXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRK 380
            +L+ + DKL+V+DF A WCGPC+ IAP  + L+Q++ D V V  V+VD+N D   +  V SMPTF F K   +   F G + DKL K
Sbjct:   14 QLILAEDKLVVIDFYADWCGPCKIIAPKLDELAQQYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAK 100
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txn (thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162])

HSP 1 Score: 82.8037 bits (203), Expect = 1.023e-20
Identity = 54/107 (50.47%), Postives = 69/107 (64.49%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MV E+     FD  L +  DKL+VVDFTATWCGPCQ I P F  LS+  E  +VVF+KVDVD   D A  C ++ MPTFHFYK+     +FSG+++ KL + I  +K
Sbjct:    1 MVLEIEDKAAFDNALKNAGDKLVVVDFTATWCGPCQTIGPYFKLLSEKPENKNVVFLKVDVDDAQDVAALCGISCMPTFHFYKNGKKVDEFSGSNQSKLEEKINSHK 107
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: TXN (zgc:56493 [Source:ZFIN;Acc:ZDB-GENE-030131-8581])

HSP 1 Score: 82.0333 bits (201), Expect = 2.028e-20
Identity = 52/107 (48.60%), Postives = 72/107 (67.29%), Query Frame = 3 
Query:   99 LVTVTE----FDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            ++ V E    FD+ LA   DKL+VVDFTATWCGPCQ IAP +  LS+  ++ +VVF+KVDVD   D A+ C++  MPTFHFYK+      FSG+++ KL + +  +K
Sbjct:    1 MIVVIEDQDGFDKALAGAGDKLVVVDFTATWCGPCQSIAPFYKGLSENPDYSNVVFLKVDVDDAQDVAQSCEIKCMPTFHFYKNGKKLDDFSGSNQTKLEEMVKQHK 107
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txn (thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162])

HSP 1 Score: 78.5666 bits (192), Expect = 3.985e-19
Identity = 51/97 (52.58%), Postives = 65/97 (67.01%), Query Frame = 3 
Query:  117 FDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            FD  L +  DKL+VVDFTATWCGPCQ I P F  LS+  E  +VVF+KVDVD   D A  C ++ MPTFHFYK+     +FSG+++ KL + I  +K
Sbjct:    9 FDNALKNAGDKLVVVDFTATWCGPCQTIGPYFKLLSEKPENKNVVFLKVDVDDAQDVAALCGISCMPTFHFYKNGKKVDEFSGSNQSKLEEKINSHK 105
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txnl1 (thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-040426-701])

HSP 1 Score: 58.9214 bits (141), Expect = 1.750e-10
Identity = 35/88 (39.77%), Postives = 51/88 (57.95%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT + C PC +IAP FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELSGAGSRLTVVKFTMSGCRPCVRIAPAFNMLSNKYPQVVFLEVDVHVCQATAAANNISATPTFLFFRNKVRVDQYQGADASGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Zebrafish
Match: txnl1 (thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-040426-701])

HSP 1 Score: 58.9214 bits (141), Expect = 1.784e-10
Identity = 35/88 (39.77%), Postives = 51/88 (57.95%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT + C PC +IAP FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELSGAGSRLTVVKFTMSGCRPCVRIAPAFNMLSNKYPQVVFLEVDVHVCQATAAANNISATPTFLFFRNKVRVDQYQGADASGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: ENSXETT00000029198.1 (MGC80314 protein [Source:NCBI gene;Acc:100170420])

HSP 1 Score: 95.1301 bits (235), Expect = 2.082e-25
Identity = 58/105 (55.24%), Postives = 73/105 (69.52%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MVR + ++ EF  +L  + DKL+VVDFTATWCGPC+ I+PVF  LS E PDVVF+KVDVD   D A  C V  MPTFHFYK+    H+FSGA++  L + + D K
Sbjct:    1 MVRHVESLDEFQNILKEAGDKLVVVDFTATWCGPCKMISPVFEKLSVENPDVVFIKVDVDDAQDVAAHCDVKCMPTFHFYKNGQKVHEFSGANQASLIQKVQDLK 105
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: btg5.3 (B-cell translocation gene 5, gene 3 [Source:Xenbase;Acc:XB-GENE-5805799])

HSP 1 Score: 82.0333 bits (201), Expect = 2.150e-20
Identity = 46/82 (56.10%), Postives = 59/82 (71.95%), Query Frame = 3 
Query:  141 DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            +KL+V+DFTA WCGPCQ+IAP F  LS EFPD+V  KVDVD  +D A+ C ++SMPTF F+K      +FSGA   KL++ I
Sbjct:   18 EKLVVIDFTAKWCGPCQRIAPDFEKLSTEFPDIVLYKVDVDDASDVAQVCGISSMPTFIFFKSGKQVERFSGADIKKLKETI 99
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: btg5.3 (B-cell translocation gene 5, gene 3 [Source:Xenbase;Acc:XB-GENE-5805799])

HSP 1 Score: 75.8702 bits (185), Expect = 8.291e-18
Identity = 45/83 (54.22%), Postives = 59/83 (71.08%), Query Frame = 3 
Query:   87 MVRELVTVTEFD-ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDN 332
            MV+ L +V E+   L  + +KL+V+DFTA WCGPCQ+IAP F  LS EFPD+V  KVDVD  +D A+ C ++SMPTF F+K  
Sbjct:    1 MVKYLASVEEYQCALKDAGEKLVVIDFTAKWCGPCQRIAPDFEKLSTEFPDIVLYKVDVDDASDVAQVCGISSMPTFIFFKSG 83
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: ENSXETT00000014226.1 (uncharacterized loc100170428 [Source:NCBI gene;Acc:100170428])

HSP 1 Score: 60.8474 bits (146), Expect = 4.055e-12
Identity = 40/101 (39.60%), Postives = 57/101 (56.44%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            M+R L +V E    L     KL++V+F++  CG C  +AP +  L  E+PD++  KV  D      + C++TS PTF FYKD     QFSGA   +LR+ I
Sbjct:    1 MIRYLRSVEELQYALRDAGQKLVLVNFSSHKCGQCTIVAPEYEKLCTEYPDILLYKVLDDAPKL-CQHCEITSTPTFAFYKDRLKIKQFSGADIVQLRETI 100
[Close]
BLAST of Thioredoxin vs. Ensembl Xenopus
Match: fabp2 (fatty acid binding protein 2 [Source:Xenbase;Acc:XB-GENE-485137])

HSP 1 Score: 60.077 bits (144), Expect = 6.742e-12
Identity = 40/101 (39.60%), Postives = 58/101 (57.43%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            M+R L +V E    L  +  KL++V+F++  CG C  +AP +  L  E+PD++  KV  D      + C++TS PTF FYKD     QFSGA   +LR+ I
Sbjct:    1 MIRYLRSVEELQYALRDAGQKLVLVNFSSHKCGQCTIVAPEYEKLCTEYPDILLYKVLDDAPKL-CQHCEITSTPTFVFYKDRLKIKQFSGADIVQLRETI 100
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txn1 (thioredoxin 1 [Source:MGI Symbol;Acc:MGI:98874])

HSP 1 Score: 82.4185 bits (202), Expect = 1.284e-20
Identity = 50/103 (48.54%), Postives = 71/103 (68.93%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            MV+ + +   F E LA+  DKL+VVDF+ATWCGPC+ I P F++L  ++ +VVF++VDVD   D A  C+V  MPTF FYK      +FSGA+++KL  +IT+
Sbjct:    1 MVKLIESKEAFQEALAAAGDKLVVVDFSATWCGPCKMIKPFFHSLCDKYSNVVFLEVDVDDCQDVAADCEVKCMPTFQFYKKGQKVGEFSGANKEKLEASITE 103
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txndc8 (thioredoxin domain containing 8 [Source:MGI Symbol;Acc:MGI:1914652])

HSP 1 Score: 68.9366 bits (167), Expect = 6.805e-15
Identity = 37/85 (43.53%), Postives = 60/85 (70.59%), Query Frame = 3 
Query:   75 QIIKMVRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYK 326
            Q++ MV+ +  ++E  EL + + +KL+VV+F+A WCGPC+ IAPVF  +S ++ +V F +VDVD + + AE C +T +PTF  +K
Sbjct:   23 QMLIMVKRIKNMSELKELFSDAGNKLVVVEFSAKWCGPCKTIAPVFQAMSLKYQNVTFAQVDVDSSKELAEHCDITMLPTFQMFK 107
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txndc2 (thioredoxin domain containing 2 (spermatozoa) [Source:MGI Symbol;Acc:MGI:2389312])

HSP 1 Score: 67.781 bits (164), Expect = 2.592e-13
Identity = 40/103 (38.83%), Postives = 67/103 (65.05%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            +VR +    EF+E+L    +KL+ VDF+A WCGPC+ + P+F++LS +  DV+F++VD +      + C++  +PTF FYK+     +FSGA   KL ++I++
Sbjct:  446 LVRVIKDKEEFEEVLKDAGEKLVAVDFSAAWCGPCRMMKPLFHSLSLKHEDVIFLEVDTEDCEQLVQDCEIFHLPTFQFYKNEEKVGEFSGALVGKLERSISE 548
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txndc2 (thioredoxin domain containing 2 (spermatozoa) [Source:MGI Symbol;Acc:MGI:2389312])

HSP 1 Score: 67.3958 bits (163), Expect = 2.872e-13
Identity = 40/103 (38.83%), Postives = 67/103 (65.05%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            +VR +    EF+E+L    +KL+ VDF+A WCGPC+ + P+F++LS +  DV+F++VD +      + C++  +PTF FYK+     +FSGA   KL ++I++
Sbjct:  439 LVRVIKDKEEFEEVLKDAGEKLVAVDFSAAWCGPCRMMKPLFHSLSLKHEDVIFLEVDTEDCEQLVQDCEIFHLPTFQFYKNEEKVGEFSGALVGKLERSISE 541
[Close]
BLAST of Thioredoxin vs. Ensembl Mouse
Match: Txnl1 (thioredoxin-like 1 [Source:MGI Symbol;Acc:MGI:1860078])

HSP 1 Score: 58.151 bits (139), Expect = 3.838e-10
Identity = 33/88 (37.50%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL  +  +L VV FT   CGPC +IAP F+++S ++P  VF++VDV +   TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKI 103
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q98TX1|THIO_OPHHA (Thioredoxin OS=Ophiophagus hannah OX=8665 GN=TXN PE=3 SV=3)

HSP 1 Score: 90.8929 bits (224), Expect = 4.673e-23
Identity = 53/101 (52.48%), Postives = 74/101 (73.27%), Query Frame = 3 
Query:   87 MVRELVTVTEFD-ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            MV+ +  +TEF  EL  +  KLIVVDF+ATWCGPC+ I P F+++ +++PDVVF+++DVD   D A  C V  MPTF FYK+N   H+FSGA+++KL +AI
Sbjct:    1 MVKIVGDLTEFRAELSNAGSKLIVVDFSATWCGPCKMIKPFFHSMVEKYPDVVFIEIDVDDAQDVASHCDVKCMPTFQFYKNNEKVHEFSGANKEKLEEAI 101
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|Q9DGI3|THIO_ICTPU (Thioredoxin OS=Ictalurus punctatus OX=7998 GN=txn PE=3 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.441e-22
Identity = 54/107 (50.47%), Postives = 72/107 (67.29%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTL--SQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MV  +  +  F   L +  DKL+VVDFTATWCGPCQKI P+F TL  S+++ +VVF+KVDVD   D +  C +  MPTFHFYK+     +FSGA+E  L++ I D+K
Sbjct:    1 MVVHIENLNAFSAALKNAGDKLVVVDFTATWCGPCQKIGPIFETLSKSEDYQNVVFLKVDVDDAADVSSHCDIKCMPTFHFYKNGQKIDEFSGANEQTLKQKINDHK 107
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|O96952|THIO_GEOCY (Thioredoxin OS=Geodia cydonium OX=6047 GN=THIO PE=3 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 1.703e-22
Identity = 56/106 (52.83%), Postives = 75/106 (70.75%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDN-TLKHQFSGASEDKLRKAITDNK 398
            MV  L T  +FD+ L  + DKL+V+DFTA+WCGPCQ+IAP +  +++EFPDV+F KVDVD+N++TAE  K+ +MPTF FYK    L     GA+E  LR+ I  NK
Sbjct:    1 MVNFLKTKADFDQALKDAGDKLVVIDFTASWCGPCQRIAPKYVEMAKEFPDVIFYKVDVDENDETAEAEKIQAMPTFKFYKSGKALSDYVQGANEAGLREKIKKNK 106
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|P22803|TRX2_YEAST (Thioredoxin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TRX2 PE=1 SV=3)

HSP 1 Score: 85.5001 bits (210), Expect = 6.424e-21
Identity = 47/103 (45.63%), Postives = 69/103 (66.99%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            MV +L + +E+D  LAS DKL+VVDF ATWCGPC+ IAP+    ++++ D  F K+DVD+ +D A+K +V+SMPT  FYK      +  GA+   +++AI  N
Sbjct:    1 MVTQLKSASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAIASN 103
[Close]
BLAST of Thioredoxin vs. UniProt/SwissProt
Match: sp|P10599|THIO_HUMAN (Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3)

HSP 1 Score: 85.5001 bits (210), Expect = 6.460e-21
Identity = 49/103 (47.57%), Postives = 74/103 (71.84%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELL-ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            MV+++ + T F E L A+ DKL+VVDF+ATWCGPC+ I P F++LS+++ +V+F++VDVD   D A +C+V  MPTF F+K      +FSGA+++KL   I +
Sbjct:    1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINE 103
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A068AX24 (Thioredoxin OS=Dugesia japonica OX=6161 GN=Trx PE=2 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.377e-30
Identity = 66/104 (63.46%), Postives = 82/104 (78.85%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MVR+L T+ EF+E+L S DKLIVVDFTATWCGPCQ I P+F  LS+E  DVVFVKVDVD+N++TA+ C +++MPT HFYKD  L H F GAS+ KL++AI   K
Sbjct:    1 MVRQLKTLAEFNEVLKSTDKLIVVDFTATWCGPCQHIGPIFVKLSEELTDVVFVKVDVDENDETAKHCNISAMPTLHFYKDTKLVHDFCGASDVKLKQAIVQYK 104
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: Q962B7 (Thioredoxin OS=Branchiostoma belcheri OX=7741 PE=2 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 4.632e-26
Identity = 60/104 (57.69%), Postives = 78/104 (75.00%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MV+ + T   FD+LLA  DKLIVVDFTA+WCGPC+ IAPVF  L++E PDVVFVKVDVD N++TA  C +++MPTFH Y++     +  GASE+KLR+ +  NK
Sbjct:    1 MVQMIETKAAFDKLLAETDKLIVVDFTASWCGPCRMIAPVFEKLAEENPDVVFVKVDVDANDETAGACGISAMPTFHCYRNGAKVEELCGASEEKLREMVAKNK 104
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: A0A3B4WGX5 (Thioredoxin OS=Seriola lalandi dorsalis OX=1841481 PE=3 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 8.733e-26
Identity = 60/93 (64.52%), Postives = 74/93 (79.57%), Query Frame = 3 
Query:  111 TEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
             EFD+ LA + DKL+VVDFTA+WCGPCQ+IAPVF  L+ E PDVVFVKVDVD+N++ A  C ++SMPTF FYK     H+FSGASE+K+R AI
Sbjct:    7 AEFDKALADAGDKLVVVDFTASWCGPCQRIAPVFAALADEMPDVVFVKVDVDENDEVASDCGISSMPTFQFYKSGAKVHEFSGASEEKIRDAI 99
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: R1DZ00 (Uncharacterized protein OS=Emiliania huxleyi OX=2903 GN=EMIHUDRAFT_436615 PE=4 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 2.597e-25
Identity = 63/100 (63.00%), Postives = 77/100 (77.00%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            V  L T  EFD+ LA + DKL+VVDFTA+WCGPCQ+IAPVF  L+ E PDVVFVKVDVD+N++ A  C ++SMPTF FYK     H+FSGASE+K+R AI
Sbjct:  153 VAMLDTKAEFDKALADAGDKLVVVDFTASWCGPCQRIAPVFAALADEMPDVVFVKVDVDENDEVASDCGISSMPTFQFYKSGAKVHEFSGASEEKIRDAI 252
[Close]
BLAST of Thioredoxin vs. TrEMBL
Match: B6VFL5 (Thioredoxin OS=Bombina orientalis OX=8346 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 1.344e-22
Identity = 55/105 (52.38%), Postives = 75/105 (71.43%), Query Frame = 3 
Query:   87 MVRELVTVTEFDE-LLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MVR +  + EF + L+ + DKL+VVDFTATWCGPC+ IAP F +LS+++PDVVF+KVDVD   D A  C +  MPTFHFYK+    H FSGA+++ L + + + K
Sbjct:    1 MVRHIENLEEFKQALVDAGDKLVVVDFTATWCGPCKMIAPFFKSLSEKYPDVVFLKVDVDDAQDVAASCDIKCMPTFHFYKNGEKVHDFSGANQNTLEQKVVELK 105
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: zgc:56493 (thioredoxin-like [Source:NCBI gene;Acc:103040975])

HSP 1 Score: 81.6481 bits (200), Expect = 1.824e-20
Identity = 51/97 (52.58%), Postives = 68/97 (70.10%), Query Frame = 3 
Query:  117 FDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            FD+ LA   DKL+VVDFTATWCGPCQ IAP +  LS+  +  +VVF+KVDVD   D A+ C++  MPTFHFYK+     +FSG+++ KL + +  NK
Sbjct:   11 FDKALAEAGDKLVVVDFTATWCGPCQSIAPFYKGLSEKPDNGNVVFLKVDVDDAQDVAQSCEIKCMPTFHFYKNGKKVDEFSGSNQAKLEELVNTNK 107
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txn (thioredoxin-like [Source:NCBI gene;Acc:103039731])

HSP 1 Score: 73.559 bits (179), Expect = 3.049e-17
Identity = 50/106 (47.17%), Postives = 67/106 (63.21%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            V E+     FD+ L  +  KL+VVDFTATWCGPC+ IAP +  LS   +  +VVF+KVDVD   D A  C++  MPTFHFYK+     +FSG + DKL + +  +K
Sbjct:    3 VIEIEDKDSFDKALRDAGSKLVVVDFTATWCGPCKMIAPYYKELSDNPQNSNVVFLKVDVDDAQDVAAHCEIKCMPTFHFYKNGKKIDEFSGGNRDKLVEILNKHK 108
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:103021638])

HSP 1 Score: 60.077 bits (144), Expect = 6.694e-11
Identity = 39/107 (36.45%), Postives = 62/107 (57.94%), Query Frame = 3 
Query:   90 VRELVTVTEFD-ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGAS----EDKLRKAITDN 395
            V+ +    EF  EL ++  +L VV FT   C PC +IAP FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA     EDK+++ + ++
Sbjct:    4 VKVIANDAEFQPELASAGSRLAVVKFTMAGCRPCLRIAPAFNMLSSKYPQVVFLEVDVHVCQGTAAANNISATPTFLFFRNKVRVDQYQGADASGLEDKIKQHVEND 110
[Close]
BLAST of Thioredoxin vs. Ensembl Cavefish
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:103021638])

HSP 1 Score: 59.6918 bits (143), Expect = 7.140e-11
Identity = 39/107 (36.45%), Postives = 62/107 (57.94%), Query Frame = 3 
Query:   90 VRELVTVTEFD-ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGAS----EDKLRKAITDN 395
            V+ +    EF  EL ++  +L VV FT   C PC +IAP FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA     EDK+++ + ++
Sbjct:    4 VKVIANDAEFQPELASAGSRLAVVKFTMAGCRPCLRIAPAFNMLSSKYPQVVFLEVDVHVCQGTAAANNISATPTFLFFRNKVRVDQYQGADASGLEDKIKQHVEND 110
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009652.1 (pep scaffold:Pmarinus_7.0:GL478563:4231:10899:-1 gene:ENSPMAG00000008707.1 transcript:ENSPMAT00000009652.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.3294 bits (181), Expect = 3.174e-18
Identity = 40/83 (48.19%), Postives = 58/83 (69.88%), Query Frame = 3 
Query:  144 KLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            KL+V+DF+ATWCGPC+ I+P+F+  + E+ +VVF  VDVD   D AE C + +MPTF F+K+N    +  GA++D L K + D
Sbjct:   21 KLVVIDFSATWCGPCKIISPIFHAFANEYHNVVFCVVDVDDAPDIAELCNIKAMPTFIFFKNNEKVGEVMGANKDHLEKTLKD 103
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007779.1 (pep scaffold:Pmarinus_7.0:GL477155:15795:22678:-1 gene:ENSPMAG00000007027.1 transcript:ENSPMAT00000007779.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 1.637e-10
Identity = 37/94 (39.36%), Postives = 57/94 (60.64%), Query Frame = 3 
Query:  111 TEFDELLA-SCDKLIVVDFTATWCGPCQKIAPVFNTLSQ-EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            ++FDE+   +  +LI++ FTA WCGPCQ+I   ++T+++ E  + VF +VDVD+  D      +  MPTF F+KD     +  G S+  LRK I
Sbjct:    9 SDFDEIKGCAGSRLIILFFTAKWCGPCQQIKEPYHTMAEKEEYNAVFCEVDVDEAADLLSSFGINCMPTFVFFKDGIQLEKLEGGSQGNLRKRI 102
[Close]
BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Match: pdia4 (protein disulfide isomerase family A, member 4 [Source:ZFIN;Acc:ZDB-GENE-030131-5493])

HSP 1 Score: 44.669 bits (104), Expect = 3.610e-6
Identity = 27/92 (29.35%), Postives = 49/92 (53.26%), Query Frame = 3 
Query:  102 VTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEF----PXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASE 365
            +T + FDE++   D +I+V+F A WCG C+K+AP +   +QE     P +   KVD    ++  ++  V+  PT   ++     + ++G  E
Sbjct:  176 LTESNFDEIVNDAD-IILVEFYAPWCGHCKKLAPEYEKAAQELSKNTPPIPLAKVDATVESELGKRFGVSGYPTLKLFRKGKA-YDYNGPRE 265
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX2 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx1p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases under DNA replication stress; TRX2 has a paralog, TRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000003441])

HSP 1 Score: 85.5001 bits (210), Expect = 9.251e-23
Identity = 47/103 (45.63%), Postives = 69/103 (66.99%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            MV +L + +E+D  LAS DKL+VVDF ATWCGPC+ IAP+    ++++ D  F K+DVD+ +D A+K +V+SMPT  FYK      +  GA+   +++AI  N
Sbjct:    1 MVTQLKSASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAIASN 103
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX1 (Cytoplasmic thioredoxin isoenzyme; part of thioredoxin system which protects cells against oxidative and reductive stress; forms LMA1 complex with Pbi2p; acts as a cofactor for Tsa1p; required for ER-Golgi transport and vacuole inheritance; with Trx2p, facilitates mitochondrial import of small Tims Tim9p, Tim10p, Tim13p by maintaining them in reduced form; abundance increases iunder DNA replication stress; TRX1 has a paralog, TRX2, that arose from the whole genome duplication [Source:SGD;Acc:S000004033])

HSP 1 Score: 77.7962 bits (190), Expect = 7.588e-20
Identity = 44/103 (42.72%), Postives = 66/103 (64.08%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDN 395
            MV +  T +EFD  +A  DKL+VVDF ATWCGPC+ IAP+    S+++P   F K+DVD+  D A+K +V++MPT   +K+     +  GA+   +++AI  N
Sbjct:    1 MVTQFKTASEFDSAIAQ-DKLVVVDFYATWCGPCKMIAPMIEKFSEQYPQADFYKLDVDELGDVAQKNEVSAMPTLLLFKNGKEVAKVVGANPAAIKQAIAAN 102
[Close]
BLAST of Thioredoxin vs. Ensembl Yeast
Match: TRX3 (Mitochondrial thioredoxin; highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p [Source:SGD;Acc:S000000679])

HSP 1 Score: 73.9442 bits (180), Expect = 5.086e-18
Identity = 48/101 (47.52%), Postives = 64/101 (63.37%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITD 392
            + +L  +TEF  L+   DKL V+DF ATWCGPC+ + P    L Q +PDV FVK DVD++ D A++C+VT+MPTF   KD  L  +  GA+   L K I D
Sbjct:   27 ITKLTNLTEFRNLIKQNDKL-VIDFYATWCGPCKMMQPHLTKLIQAYPDVRFVKCDVDESPDIAKECEVTAMPTFVLGKDGQLIGKIIGANPTALEKGIKD 126
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO46139 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RQN2])

HSP 1 Score: 78.1814 bits (191), Expect = 1.466e-19
Identity = 45/95 (47.37%), Postives = 64/95 (67.37%), Query Frame = 3 
Query:   96 ELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRK 380
            +L T  EFD+ L   +++  +DFTATWCGPC+ I P F  +++EF  V   KVDVD N++TAE   +T+MPTF FYK+  +  +  GASE KL++
Sbjct:    3 QLNTKGEFDKFLKD-NEVAAIDFTATWCGPCRMIGPKFEEMAKEFKGVKCAKVDVDVNSETAESEGITAMPTFRFYKNGEMVDEVVGASESKLKE 96
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO33372 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7SSF5])

HSP 1 Score: 77.411 bits (189), Expect = 3.058e-19
Identity = 45/88 (51.14%), Postives = 58/88 (65.91%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            E+  +  +L+V+DFTATWCGPC+ IAPVF  LS +F DVVF+KVDVD+   TAE C + +MPTFHFY +     +  GA    L   I
Sbjct:   19 EIERAGSRLVVIDFTATWCGPCKSIAPVFTNLSMKFMDVVFLKVDVDQCQLTAESCGIRAMPTFHFYHNKAKIDELRGADPGALENKI 106
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO45413 (Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RT76])

HSP 1 Score: 69.707 bits (169), Expect = 3.912e-16
Identity = 45/105 (42.86%), Postives = 69/105 (65.71%), Query Frame = 3 
Query:   90 VRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLS-QEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            V+E+    EF+ ++ +  DKL+V+DF A WCGPC++I P F  ++ +EF DV F K+DVD+  + +E  ++T+MPTF FYK+     +  GA+E KLR+ I   K
Sbjct:   12 VKEIEERAEFNSVINNTKDKLVVIDFYAEWCGPCRQIKPKFKKMALEEFKDVFFAKIDVDELEELSEDEQITAMPTFVFYKNGQKLEKLVGANEVKLRELILKYK 116
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO41852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A4])

HSP 1 Score: 73.1738 bits (178), Expect = 4.151e-16
Identity = 48/111 (43.24%), Postives = 67/111 (60.36%), Query Frame = 3 
Query:   93 RELVTVTEFD-----ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGAS----EDKLRKAITDNK 398
            R  V V E D     EL  +  KL+V DFTA+WCGPC+ IAPV++ LS+++   VF+K+DVD   + A K  VT+MPTF F+K+     +  GA     ED ++K I D +
Sbjct:    6 RGNVKVLELDSQFTAELTNAGTKLVVADFTASWCGPCKSIAPVYSGLSEKYKQAVFLKIDVDVCQELAAKQGVTAMPTFQFFKNKVKVDEVRGADPKALEDAIKKWIGDGE 116
[Close]
BLAST of Thioredoxin vs. Ensembl Nematostella
Match: EDO47340 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMG9])

HSP 1 Score: 45.4394 bits (106), Expect = 2.754e-6
Identity = 28/91 (30.77%), Postives = 52/91 (57.14%), Query Frame = 3 
Query:  111 TEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEF---PXXXXXXXXXXXXXXTAEKCKVTSMPTFHFY-KDNTLKHQFSGASEDK 371
            + FD+++ + D  ++V+F A WCG C+ +APV+  + + F   P+ V  KVD D ++   +K  V+  PT  F+ K N    ++S   +++
Sbjct:  148 SNFDKIVKNPDNNVLVEFFAPWCGHCKNLAPVYEKVGEAFKNEPNCVIAKVDADAHSALGQKYGVSGYPTLKFFSKTNKDGEEYSSGRDEQ 238
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: ENSORLT00000009496.2 (thioredoxin [Source:NCBI gene;Acc:101173415])

HSP 1 Score: 77.7962 bits (190), Expect = 6.933e-19
Identity = 44/103 (42.72%), Postives = 65/103 (63.11%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASC-DKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEK-CKVTSMPTFHFYKDNTLKHQFSGAS----EDKLR 377
            MVRE+  + EF ++L    DKL+VVDFTA+WCGPC++IAP++  +S+   +   V + VD +       C++  MPTFHFYK      +FSGA+    E+KL+
Sbjct:    1 MVREVADLAEFKKILEDAGDKLVVVDFTASWCGPCKQIAPLYKQMSESDDNKNVVFLKVDVDEADVSVFCEIKCMPTFHFYKGGKKVDEFSGANVATLEEKLK 103
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:101158293])

HSP 1 Score: 59.6918 bits (143), Expect = 5.664e-11
Identity = 35/88 (39.77%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL A+  +L+VV FT   C PC +I+P FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELAAAGSRLVVVKFTMAGCRPCVRISPAFNALSNKYPHVVFLEVDVHVCQATAAANNISATPTFLFFRNRVRVDQYQGADAAGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Ensembl Medaka
Match: txnl1 (thioredoxin like 1 [Source:NCBI gene;Acc:101158293])

HSP 1 Score: 59.6918 bits (143), Expect = 8.018e-11
Identity = 35/88 (39.77%), Postives = 52/88 (59.09%), Query Frame = 3 
Query:  123 ELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            EL A+  +L+VV FT   C PC +I+P FN LS ++P VVF++VDV     TA    +++ PTF F+++     Q+ GA    L + I
Sbjct:   16 ELAAAGSRLVVVKFTMAGCRPCVRISPAFNALSNKYPHVVFLEVDVHVCQATAAANNISATPTFLFFRNRVRVDQYQGADAAGLEEKI 103
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000030342.1 (SMESG000030342.1)

HSP 1 Score: 182.956 bits (463), Expect = 1.902e-60
Identity = 104/104 (100.00%), Postives = 104/104 (100.00%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 398
            MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPDVVFVKVDVDKNNDTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK
Sbjct:    1 MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPDVVFVKVDVDKNNDTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK 104
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000033877.1 (SMESG000033877.1)

HSP 1 Score: 71.633 bits (174), Expect = 3.039e-15
Identity = 44/98 (44.90%), Postives = 63/98 (64.29%), Query Frame = 3 
Query:  132 ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK*TMN*TPFI 425
            AS +KL+V+DF ATWCGPC+ IAP  + LS +FP+V F+KVDV+K    AE+  V +MPTF F K+     +  GA+   L   +T++  +   TPF+
Sbjct:   24 ASVNKLVVIDFYATWCGPCKNIAPFVHRLSVKFPNVTFLKVDVEKFPVIAERYNVNAMPTFIFLKNKIKMDELKGANASVLEAKVTEHAGS---TPFL 118
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000033877.1 (SMESG000033877.1)

HSP 1 Score: 71.633 bits (174), Expect = 3.272e-15
Identity = 44/98 (44.90%), Postives = 63/98 (64.29%), Query Frame = 3 
Query:  132 ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAITDNK*TMN*TPFI 425
            AS +KL+V+DF ATWCGPC+ IAP  + LS +FP+V F+KVDV+K    AE+  V +MPTF F K+     +  GA+   L   +T++  +   TPF+
Sbjct:   24 ASVNKLVVIDFYATWCGPCKNIAPFVHRLSVKFPNVTFLKVDVEKFPVIAERYNVNAMPTFIFLKNKIKMDELKGANASVLEAKVTEHAGS---TPFL 118
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000039109.1 (SMESG000039109.1)

HSP 1 Score: 62.7734 bits (151), Expect = 3.287e-13
Identity = 40/99 (40.40%), Postives = 66/99 (66.67%), Query Frame = 3 
Query:   87 MVRELVTVTEFDELL-ASCDKLIVVDFTATWCGPCQKIAPVFNTLSQ--EFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKL 374
            M   + +  EF + +  +  KL++VDF A WCGPC+ ++P F+  ++  +F DV+F+KVDVD+  + AEK  ++ MPTF F+++     +FSGA++DKL
Sbjct:    1 MATSVESEEEFQDFIDGNGSKLVIVDFWAEWCGPCRLMSPAFDKFAKDSQFKDVIFLKVDVDELGELAEKYDISCMPTFIFFRNGEKIDEFSGANKDKL 99
[Close]
BLAST of Thioredoxin vs. Planmine SMEST
Match: SMESG000023196.1 (SMESG000023196.1)

HSP 1 Score: 58.9214 bits (141), Expect = 9.402e-12
Identity = 31/79 (39.24%), Postives = 49/79 (62.03%), Query Frame = 3 
Query:  150 IVVDFTATWCGPCQKIAPVFNTLSQEFPXXXXXXXXXXXXXXTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI 386
            I+ DF+A+WCGPC  IAP++  LS+ +  + F+K+DVD  +D A    +TS+PTF F+      H   GA  ++L+  +
Sbjct:   14 IIADFSASWCGPCNNIAPIYEDLSETYDKISFLKIDVDSQSDIATLYNITSLPTFVFFNHGAQIHMIIGADVNQLKSNL 92
The following BLAST results are available for this feature:
BLAST of Thioredoxin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TXN1.345e-2147.57thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435][more]
TXN5.995e-1838.83thioredoxin [Source:HGNC Symbol;Acc:HGNC:12435][more]
TXNL16.262e-1037.50thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12... [more]
TXNL16.262e-1037.50thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12... [more]
TXNL16.386e-1037.50thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12... [more]
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BLAST of Thioredoxin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trx-13.799e-1337.86Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
Y55F3AR.29.373e-1342.55pep chromosome:WBcel235:IV:1094545:1096723:1 gene:... [more]
trx-11.326e-1138.54Thioredoxin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
png-13.006e-1133.66Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagin... [more]
txl-16.439e-1141.98ThioredoXin-Like; Thioredoxin-like protein; Thiore... [more]
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BLAST of Thioredoxin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Txl3.518e-1546.15gene:FBgn0035631 transcript:FBtr0077098[more]
dhd1.428e-1340.24gene:FBgn0011761 transcript:FBtr0070749[more]
dhd1.428e-1340.24gene:FBgn0011761 transcript:FBtr0345745[more]
TrxT1.555e-1245.98gene:FBgn0029752 transcript:FBtr0070755[more]
TrxT1.555e-1245.98gene:FBgn0029752 transcript:FBtr0340478[more]
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BLAST of Thioredoxin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
txn1.023e-2050.47thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162][more]
TXN2.028e-2048.60zgc:56493 [Source:ZFIN;Acc:ZDB-GENE-030131-8581][more]
txn3.985e-1952.58thioredoxin [Source:ZFIN;Acc:ZDB-GENE-040718-162][more]
txnl11.750e-1039.77thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
txnl11.784e-1039.77thioredoxin-like 1 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
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BLAST of Thioredoxin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000029198.12.082e-2555.24MGC80314 protein [Source:NCBI gene;Acc:100170420][more]
btg5.32.150e-2056.10B-cell translocation gene 5, gene 3 [Source:Xenbas... [more]
btg5.38.291e-1854.22B-cell translocation gene 5, gene 3 [Source:Xenbas... [more]
ENSXETT00000014226.14.055e-1239.60uncharacterized loc100170428 [Source:NCBI gene;Acc... [more]
fabp26.742e-1239.60fatty acid binding protein 2 [Source:Xenbase;Acc:X... [more]
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BLAST of Thioredoxin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Txn11.284e-2048.54thioredoxin 1 [Source:MGI Symbol;Acc:MGI:98874][more]
Txndc86.805e-1543.53thioredoxin domain containing 8 [Source:MGI Symbol... [more]
Txndc22.592e-1338.83thioredoxin domain containing 2 (spermatozoa) [Sou... [more]
Txndc22.872e-1338.83thioredoxin domain containing 2 (spermatozoa) [Sou... [more]
Txnl13.838e-1037.50thioredoxin-like 1 [Source:MGI Symbol;Acc:MGI:1860... [more]
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BLAST of Thioredoxin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q98TX1|THIO_OPHHA4.673e-2352.48Thioredoxin OS=Ophiophagus hannah OX=8665 GN=TXN P... [more]
sp|Q9DGI3|THIO_ICTPU1.441e-2250.47Thioredoxin OS=Ictalurus punctatus OX=7998 GN=txn ... [more]
sp|O96952|THIO_GEOCY1.703e-2252.83Thioredoxin OS=Geodia cydonium OX=6047 GN=THIO PE=... [more]
sp|P22803|TRX2_YEAST6.424e-2145.63Thioredoxin-2 OS=Saccharomyces cerevisiae (strain ... [more]
sp|P10599|THIO_HUMAN6.460e-2147.57Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV... [more]
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BLAST of Thioredoxin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A068AX242.377e-3063.46Thioredoxin OS=Dugesia japonica OX=6161 GN=Trx PE=... [more]
Q962B74.632e-2657.69Thioredoxin OS=Branchiostoma belcheri OX=7741 PE=2... [more]
A0A3B4WGX58.733e-2664.52Thioredoxin OS=Seriola lalandi dorsalis OX=1841481... [more]
R1DZ002.597e-2563.00Uncharacterized protein OS=Emiliania huxleyi OX=29... [more]
B6VFL51.344e-2252.38Thioredoxin OS=Bombina orientalis OX=8346 PE=2 SV=... [more]
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BLAST of Thioredoxin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
zgc:564931.824e-2052.58thioredoxin-like [Source:NCBI gene;Acc:103040975][more]
txn3.049e-1747.17thioredoxin-like [Source:NCBI gene;Acc:103039731][more]
txnl16.694e-1136.45thioredoxin like 1 [Source:NCBI gene;Acc:103021638... [more]
txnl17.140e-1136.45thioredoxin like 1 [Source:NCBI gene;Acc:103021638... [more]
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BLAST of Thioredoxin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000009652.13.174e-1848.19pep scaffold:Pmarinus_7.0:GL478563:4231:10899:-1 g... [more]
ENSPMAT00000007779.11.637e-1039.36pep scaffold:Pmarinus_7.0:GL477155:15795:22678:-1 ... [more]
pdia43.610e-629.35protein disulfide isomerase family A, member 4 [So... [more]
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BLAST of Thioredoxin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
TRX29.251e-2345.63Cytoplasmic thioredoxin isoenzyme; part of thiored... [more]
TRX17.588e-2042.72Cytoplasmic thioredoxin isoenzyme; part of thiored... [more]
TRX35.086e-1847.52Mitochondrial thioredoxin; highly conserved oxidor... [more]
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BLAST of Thioredoxin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO461391.466e-1947.37Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RQN2][more]
EDO333723.058e-1951.14Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7SSF5][more]
EDO454133.912e-1642.86Thioredoxin [Source:UniProtKB/TrEMBL;Acc:A7RT76][more]
EDO418524.151e-1643.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473402.754e-630.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Thioredoxin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000009496.26.933e-1942.72thioredoxin [Source:NCBI gene;Acc:101173415][more]
txnl15.664e-1139.77thioredoxin like 1 [Source:NCBI gene;Acc:101158293... [more]
txnl18.018e-1139.77thioredoxin like 1 [Source:NCBI gene;Acc:101158293... [more]
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BLAST of Thioredoxin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000030342.11.902e-60100.00SMESG000030342.1[more]
SMESG000033877.13.039e-1544.90SMESG000033877.1[more]
SMESG000033877.13.272e-1544.90SMESG000033877.1[more]
SMESG000039109.13.287e-1340.40SMESG000039109.1[more]
SMESG000023196.19.402e-1239.24SMESG000023196.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30000901 ID=SMED30000901|Name=Thioredoxin|organism=Schmidtea mediterranea sexual|type=transcript|length=508bp
AAAAATTATACGTCGAAGTGTTTTGTTTGAATTTTTAAATCATAGTATAA
AATAAAGTTTCACAATAGTAAATACAAATAATAAAAATGGTTCGAGAATT
GGTTACAGTTACAGAATTTGATGAGCTTTTGGCTTCTTGTGATAAGTTAA
TTGTTGTTGACTTTACTGCTACATGGTGTGGTCCTTGCCAGAAAATTGCA
CCTGTATTCAACACTTTAAGTCAAGAATTTCCTGACGTCGTTTTCGTTAA
AGTTGACGTGGACAAGAACAACGATACAGCTGAAAAATGCAAGGTGACAT
CAATGCCGACATTCCATTTCTACAAGGACAACACTTTGAAACATCAATTT
AGTGGAGCATCTGAAGATAAATTGCGAAAAGCTATTACTGATAACAAATA
AACAATGAATTAAACACCGTTTATTAGAAGTGTTGATTAATAAAAGCTGT
GTCTTAAAGTAGTTTGGAATTAGACATTTTAAATATATGTATATTTCCTC
AAAAAAAA
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protein sequence of SMED30000901-orf-1

>SMED30000901-orf-1 ID=SMED30000901-orf-1|Name=SMED30000901-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=105bp
MVRELVTVTEFDELLASCDKLIVVDFTATWCGPCQKIAPVFNTLSQEFPD
VVFVKVDVDKNNDTAEKCKVTSMPTFHFYKDNTLKHQFSGASEDKLRKAI
TDNK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000464GABAergic neuron
Vocabulary: INTERPRO
TermDefinition
IPR036249Thioredoxin-like_sf
IPR013766Thioredoxin_domain
IPR005746Thioredoxin
IPR012336Thioredoxin-like_fold
IPR017937Thioredoxin_CS
Vocabulary: biological process
TermDefinition
GO:0045454cell redox homeostasis
GO:0006662glycerol ether metabolic process
GO:0055114oxidation-reduction process
Vocabulary: molecular function
TermDefinition
GO:0015035protein disulfide oxidoreductase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00421THIOREDOXINcoord: 22..30
score: 53.27
coord: 30..39
score: 63.72
coord: 69..80
score: 36.99
NoneNo IPR availablePANTHERPTHR46115:SF1THIOREDOXIN-LIKE PROTEIN 1coord: 1..101
NoneNo IPR availablePANTHERPTHR46115FAMILY NOT NAMEDcoord: 1..101
NoneNo IPR availableCDDcd02947TRX_familycoord: 10..100
e-value: 1.71023E-26
score: 91.8508
IPR005746ThioredoxinPIRSFPIRSF000077Thioredoxincoord: 1..104
e-value: 1.1E-30
score: 103.4
IPR013766Thioredoxin domainPFAMPF00085Thioredoxincoord: 6..101
e-value: 4.9E-31
score: 106.8
IPR013766Thioredoxin domainPROSITEPS51352THIOREDOXIN_2coord: 1..104
score: 14.242
IPR036249Thioredoxin-like superfamilyGENE3DG3DSA:3.40.30.10coord: 1..103
e-value: 1.5E-34
score: 120.2
IPR036249Thioredoxin-like superfamilySUPERFAMILYSSF52833Thioredoxin-likecoord: 2..102
IPR017937Thioredoxin, conserved sitePROSITEPS00194THIOREDOXIN_1coord: 23..41