Coiled-coil domain-containing protein 42-like protein

Overview


Name	Coiled-coil domain-containing protein 42-like protein
Smed ID	SMED30000840
Length (bp)	1029

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Coiled-coil domain-containing protein 42-like protein (SMED30000840) t-SNE clustered cells

Violin plots show distribution of expression levels for Coiled-coil domain-containing protein 42-like protein (SMED30000840) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Coiled-coil domain-containing protein 42-like protein (SMED30000840) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000840

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30000840	h1SMcG0005935	SmedASXL_009625	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30000840	h1SMcG0005935	dd_Smed_v4_12378_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30000840	h1SMcG0005935	dd_Smed_v4_12378_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30000840	h1SMcG0005935	dd_Smed_v4_12378_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30000840	h1SMcG0005935	dd_Smed_v6_12378_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
epidermis	SMED30000840	h1SMcG0005935	dd_Smed_v4_12378_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
Match: CFAP73 (cilia and flagella associated protein 73 [Source:HGNC Symbol;Acc:HGNC:37100])

HSP 1 Score: 171.014 bits (432), Expect = 3.696e-50
Identity = 107/295 (36.27%), Postives = 180/295 (61.02%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M +  ++YF+ + +EK+  K+PE+  DH+    RLLEKR+E+ + DQAL AQKE F  K  +L QR E+LE+KE +L+ S ++FDKFLQ+++A++NRAL++A EE+    ++E+E L+L T++Q   +   +L  +LK+     + LE   E    F E+ E++ R++ L  T   L  R++E    +E  + +L   ++     VL    + AQLQ+ L+ +R ++L+ + +W  I  TAA KTL  G+ RMA  NL+Q+  ++Q  P   +  ++ EGQL  +  F++DL+ +
Sbjct:    1 MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPP-TLDIEDTEGQLEHVKLFMQDLSAM 294

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
Match: CCDC42 (coiled-coil domain containing 42 [Source:HGNC Symbol;Acc:HGNC:26528])

HSP 1 Score: 158.688 bits (400), Expect = 2.600e-45
Identity = 116/296 (39.19%), Postives = 176/296 (59.46%), Query Frame = 3

Query:   42 LDDYFKTSFEEKILI---KMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQS 920
            L +YF+  + E++L    K+P  E    + +  LLEK++E   + Q +  +K+ F  ++E+L  R EEL  KE QL+  + K ++F+QEND K+ RA+KKA +E+  K Q   E+ K K E+        +L+ KLK YYIF KYLE V E SE F EI E+I RY+TL +  H L++  +E  + IE  K +L+   E K+  +LQ N +LA+LQ   D++RS  +  +  W +I  TAA KTL  G I+MAT NL+QI  K+ +  +E V+ ++   QL  I +FI+D + I +
Sbjct:   11 LAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMRHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQQNNELARLQMRFDRARSNVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTE-VALEDTHKQLDMIQQFIQDRSDIWA 304

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
Match: CCDC42 (coiled-coil domain containing 42 [Source:HGNC Symbol;Acc:HGNC:26528])

HSP 1 Score: 79.337 bits (194), Expect = 1.779e-16
Identity = 61/155 (39.35%), Postives = 92/155 (59.35%), Query Frame = 3

Query:   42 LDDYFKTSFEEKILI---KMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASED 497
            L +YF+  + E++L    K+P  E    + +  LLEK++E   + Q +  +K+ F  ++E+L  R EEL  KE QL+  + K ++F+QEND K+ RA+KKA +E+  K Q   E+ K K E+        +L+ KLK YYIF KYLE V E SE+
Sbjct:   11 LAEYFRLQYGERLLQMLQKLPNVEGASESPSIWLLEKKKETEIMHQTMVQKKKMFQRRMETLNLRWEELGVKEAQLKAHIQKSEQFIQENDQKRIRAMKKANKERELKCQHMQELTKRKQEMVALRLEHQRLSAKLKDYYIFNKYLEKVVENSEE 165

HSP 2 Score: 50.447 bits (119), Expect = 1.441e-6
Identity = 31/70 (44.29%), Postives = 42/70 (60.00%), Query Frame = 3

Query:  711 LEKDVE------WTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIED 902
            LEK VE      W +I  TAA KTL  G I+MAT NL+QI  K+ +  +E V+ ++   QL  I +FI+D
Sbjct:  156 LEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSKHLKEVTE-VALEDTHKQLDMIQQFIQD 224

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
Match: CFAP73 (cilia and flagella associated protein 73 [Source:HGNC Symbol;Acc:HGNC:37100])

HSP 1 Score: 51.9878 bits (123), Expect = 7.453e-8
Identity = 25/68 (36.76%), Postives = 40/68 (58.82%), Query Frame = 3

Query:  711 LEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            L  + +W  I  TAA KTL  G+ RMA  NL+Q+  ++Q  P   +  ++ EGQL  +  F++DL+ +
Sbjct:   58 LPGESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPP-TLDIEDTEGQLEHVKLFMQDLSAM 124

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Zebrafish
Match: cfap73 (cilia and flagella associated protein 73 [Source:ZFIN;Acc:ZDB-GENE-060526-194])

HSP 1 Score: 113.235 bits (282), Expect = 1.216e-28
Identity = 104/285 (36.49%), Postives = 162/285 (56.84%), Query Frame = 3

Query:   27 KMNLYLDDYFKTSFEEKILIKMPEKEN--DHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQ--------KQKLSDGKEVKNQ--TVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQ-IAKKYQRHPSE 842
            KMNL  +DYF+  FEE++ +   E E   D  T A +LLE R + + + +AL  QKEE  MK ESL +R E ++++E +L+ SL++++KFLQENDA++ RA+KKA  E+   R KELE+ KLKTE    L  K+ L E++ K   +Q++LE   + S  F    ++IDR + L +           + +L+ENQ        + KL   + +  Q   +L YN +L QLQ  LD  R ++ + +++  +   TAA +TL+  +++    N+YQ I   Y R  SE
Sbjct:    4 KMNL--EDYFRLVFEERLSLNKAEHEGFKDMKTTAMQLLEAREQSACVSRALEVQKEEMQMKQESLKEREENIKKEEEKLKNSLLQYNKFLQENDARRLRAIKKAEAERAQTRLKELEIQKLKTENDVLLARKELLEERVGKAKCYQEFLERAAKMSRKFENPCQVIDRIQALQSI----------NKELLENQTVLEKERERTKLELMQYINKQRTALLHYNNQLHQLQTQLDNIRIEAYKWEIKLKHFQTTAAKETLEFAQLKTTVRNIYQMIITHYIRRVSE 276

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Zebrafish
Match: si:ch1073-416d2.4 (si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121-564])

HSP 1 Score: 59.6918 bits (143), Expect = 1.611e-9
Identity = 57/197 (28.93%), Postives = 104/197 (52.79%), Query Frame = 3

Query:  123 ATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASED------FSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDK 695
             T +L+KR E+  I+  L   + +   ++ SLT+RRE L+R + + R+   +F +F++EN+ K+ RA+KK   EK   + KE E  +L  +++     + +L +++ +Y IF+++L    E   D         +  II RYETL+ +   L+++ +   D ++    +L   K+  N   L  N  L+ LQ  LD+
Sbjct:   84 CTLVLKKREELDNINTHLTHTRAQIQQRMRSLTERRELLQRAQEESRQRAERFQRFVEENELKRRRAMKKLQMEKQQSQSKEEERGELANQMERLQDRRMRLKQRVSRYKIFEEFLMKTLELLPDNYLGLGTDLVAPIIRRYETLSISRQDLLQQLQRLTDQMKTDHNQLDTLKQQHNTYKLTTNQDLSDLQTQLDQ 280

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Zebrafish
Match: si:ch1073-416d2.4 (si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121-564])

HSP 1 Score: 53.5286 bits (127), Expect = 1.136e-7
Identity = 36/116 (31.03%), Postives = 70/116 (60.34%), Query Frame = 3

Query:  123 ATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYL 470
             T +L+KR E+  I+  L   + +   ++ SLT+RRE L+R + + R+   +F +F++EN+ K+ RA+KK   EK   + KE E  +L  +++     + +L +++ +Y IF+++L
Sbjct:   79 CTLVLKKREELDNINTHLTHTRAQIQQRMRSLTERRELLQRAQEESRQRAERFQRFVEENELKRRRAMKKLQMEKQQSQSKEEERGELANQMERLQDRRMRLKQRVSRYKIFEEFL 194

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Xenopus
Match: klhl13 (kelch like family member 13 [Source:Xenbase;Acc:XB-GENE-923144])

HSP 1 Score: 220.705 bits (561), Expect = 1.968e-69
Identity = 138/295 (46.78%), Postives = 199/295 (67.46%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M   L +YF+ +FE+K+L+KMP++E+D LT ATRLLEKRREM E++QAL+ QKEEF MK ESL QRR ELE KE +L++SL KFDKFL+END+K+ RAL KA EE+     KE E L+L+ E    ++ K  L E+ +K   +Q+YL+ V E +++F E++E+IDR+ TL  T + L+KRD E+ +L E +K +L   +E     +L+ N ++AQLQ  L++ R+ + + +  W  I  TAA  TL+ G+IRM+T NL+Q   K  R  +E +S ++ E QL KI    EDL+ I
Sbjct:    1 MEFDLGEYFRAAFEDKLLVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQMRLKTE-ISVEDTEAQLEKIQICFEDLSAI 294

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Xenopus
Match: klhl13 (kelch like family member 13 [Source:Xenbase;Acc:XB-GENE-923144])

HSP 1 Score: 213.772 bits (543), Expect = 5.886e-67
Identity = 132/282 (46.81%), Postives = 192/282 (68.09%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQL 875
            M   L +YF+ +FE+K+L+KMP++E+D LT ATRLLEKRREM E++QAL+ QKEEF MK ESL QRR ELE KE +L++SL KFDKFL+END+K+ RAL KA EE+     KE E L+L+ E    ++ K  L E+ +K   +Q+YL+ V E +++F E++E+IDR+ TL  T + L+KRD E+ +L E +K +L   +E     +L+ N ++AQLQ  L++ R+ + + +  W  I  TAA  TL+ G+IRM+T NL+Q   K  R  +E +S ++ E QL
Sbjct:    1 MEFDLGEYFRAAFEDKLLVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQMRLKTE-ISVEDTEAQL 281

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Xenopus
Match: cfap73 (cilia and flagella associated protein 73 [Source:Xenbase;Acc:XB-GENE-5779653])

HSP 1 Score: 70.8626 bits (172), Expect = 2.739e-13
Identity = 75/277 (27.08%), Postives = 149/277 (53.79%), Query Frame = 3

Query:   84 IKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            ++ P ++   L    RLLE+ +E   I + L   +EE+H  +E      E+L+ KE ++R SL  + + + +++  + RAL++A + +  + Q +LE+  L+ + +   K + K   +++KY  F +YLE V +ASE F +I +++ R+ TL    +YL + +++     +  + + S   E K+ +++Q + ++ +L   L+K++ +  E ++ W  +++ AA K L  G I+ A  ++ Q     Q   S+    ++I  QL  I   I+DLT I
Sbjct:    1 MECPIRQVQRLPLPFRLLERNQE---IQKMLEEGREEYHRAMEGAALEWEKLQEKEAEIRASLEAYRESIAKDNKTRERALREAAKARRRRAQYDLELKALQEQCEELHKKRTKTKAQVQKYEKFYRYLEKVVKASEKFQDIPDLMSRFHTLV---NYLPQEEQKS----QESRSQRSHCMEEKSDSIVQLSNEIHRLYIRLEKAKKKRRESELRWNQLLKMAARKNLLLGTIQAAVLDICQTTSS-QGLGSKSFGEEDIVEQLETIREDIKDLTDI 266

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 168.318 bits (425), Expect = 3.620e-49
Identity = 121/294 (41.16%), Postives = 177/294 (60.20%), Query Frame = 3

Query:   42 LDDYFKTSFEEKILI---KMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            L +YF+  + E++L    K P  E    + + +LLEK++E   + +A+  +KE F  ++E+L  R EEL  KE QL+  + KF++F+QEND K+ RALKKA +E+  KR +  E+ K K E+        KL+ KL+ Y IF KYLE V E SE F EI E+I RY+TL +  H L++  +E  + IE  K +L+   E K+  +LQ+N +LA+LQ   D++RS  +  +  W +I  TAA KTL  G I+MAT NL+QI  K Q   S  VS ++   QL  I +FI+DL+ I
Sbjct:   11 LAEYFRLQYGERLLQLLQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSK-QLKESTQVSLEDTHKQLDMIQQFIQDLSDI 302

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
Match: Cfap73 (cilia and flagella associated protein 73 [Source:MGI Symbol;Acc:MGI:3779542])

HSP 1 Score: 124.405 bits (311), Expect = 1.398e-32
Identity = 88/293 (30.03%), Postives = 166/293 (56.66%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLT 908
            M +  ++YF+  F EK+  K  E+  D  +    +LEK+ E++  D  L AQK+E+   IES+ QR  ELE+K  +L+ S++ +DKFL+E +A+  RA +KA+EE+      + E+ +L+T+++     + +L  K+++     + L+   E    F E+ +++ R+ETL +T   L   +++    +E+ + +L   +  K   +L  N +  QL + L+ +R    + + +WT I+ +A+ KTL  G+ RMA  NLY +  + Q+   + +   ++EGQL ++ RFI +++
Sbjct:    1 MAVTWEEYFRLVFSEKVQPKPLEQTGDDSSVLQLILEKKEELAVADLGLQAQKKEYRSTIESVNQRWRELEQKGQELQGSVISYDKFLKEVEAR--RAARKAIEERKITGNLDAELRRLRTQLKELRLQRARLQRKVQRLEPCARILKRALEKRPVFEEVSDLVARFETLVSTKAALKLEEQKRLVEMESTRAQLLSLQSEKQDEMLNLNQQRTQLVEQLEAAREHRQQWESKWTEILNSASEKTLLLGRARMAVLNLYHLV-RLQQGRRQTLDVRDVEGQLEEVKRFIMNIS 290

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 92.4337 bits (228), Expect = 4.158e-22
Identity = 58/141 (41.13%), Postives = 85/141 (60.28%), Query Frame = 3

Query:  498 FSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQS 920
            F EI E+I RY+TL +  H L++  +E  + IE  K +L+   E K+  +LQ+N +LA+LQ   D++RS  +  +  W +I  TAA KTL  G I+MAT NL+QI  K Q   S  VS ++   QL  I +FI+DL+ I +
Sbjct:   18 FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYMEEKDDEILQHNNELARLQMRFDRARSDVIFWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSK-QLKESTQVSLEDTHKQLDMIQQFIQDLSDIWT 157

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
Match: Ccdc42 (coiled-coil domain containing 42 [Source:MGI Symbol;Acc:MGI:3045254])

HSP 1 Score: 83.5741 bits (205), Expect = 2.970e-18
Identity = 63/155 (40.65%), Postives = 94/155 (60.65%), Query Frame = 3

Query:   42 LDDYFKTSFEEKILI---KMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASED 497
            L +YF+  + E++L    K P  E    + + +LLEK++E   + +A+  +KE F  ++E+L  R EEL  KE QL+  + KF++F+QEND K+ RALKKA +E+  KR +  E+ K K E+        KL+ KL+ Y IF KYLE V E SE+
Sbjct:    7 LAEYFRLQYGERLLQLLQKFPNVEEQSDSPSIQLLEKKKEAKIMQEAMEHKKEAFQRRMETLNLRWEELGIKEEQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRLRLRELAKAKQEMMALRLEHQKLSVKLQDYAIFNKYLEKVVENSEE 161

HSP 2 Score: 53.1434 bits (126), Expect = 9.798e-8
Identity = 35/74 (47.30%), Postives = 43/74 (58.11%), Query Frame = 3

Query:  711 LEKDVE------WTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            LEK VE      W +I  TAA KTL  G I+MAT NL+QI  K Q   S  VS ++   QL  I +FI+DL+ I
Sbjct:  152 LEKVVENSEESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSK-QLKESTQVSLEDTHKQLDMIQQFIQDLSDI 224

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Match: sp|A7S8T5|CCD42_NEMVE (Coiled-coil domain-containing protein 42 homolog OS=Nematostella vectensis OX=45351 GN=v1g187067 PE=3 SV=1)

HSP 1 Score: 278.485 bits (711), Expect = 2.682e-91
Identity = 161/306 (52.61%), Postives = 224/306 (73.20%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQ---SRADDSI 938
            M + L++YF+T+FE+K+L+KMPE+E+DHLT ATRLLEKRREMSE++QAL AQKEEF MK+ESL QRREELERKE QLRESL+KFDKFL+END+K+ RALKKA EE+  +R K+ E+ +LK +    +K +DK+  +L+KY I+Q+YLE V E +E+F EIREII RY+TLT T   L++R+ ++ +  E +K +L    E KN  +L YN +LA LQ  L+K++S +++ + +WT+I  TAA KTL  G+I+MAT+NL+ +     RH  +    D  + QL KI  FI+DLT I     RA+++I
Sbjct:    1 MTVNLEEYFRTTFEDKLLVKMPEREDDHLTPATRLLEKRREMSEVEQALGAQKEEFQMKMESLQQRREELERKEYQLRESLLKFDKFLKENDSKRARALKKAQEERDMRRAKDCEIARLKEDTSGLMKGRDKVQHRLEKYIIYQQYLEKVLENAEEFQEIREIIARYDTLTATHQDLLERELKNQEKYEKEKARLIKFTEEKNNEILNYNNQLANLQTKLEKTQSVAVKWESQWTHIKNTAAKKTLLLGRIKMATHNLFMLV---NRHLGQTGMVDMTDKQLDKIQVFIQDLTQITLDIKRAENAI 303

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Match: sp|B0BMJ2|CC42M_XENTR (Coiled-coil domain-containing protein 42 like-2 OS=Xenopus tropicalis OX=8364 GN=TNeu058c09.1 PE=2 SV=2)

HSP 1 Score: 220.705 bits (561), Expect = 1.042e-68
Identity = 138/295 (46.78%), Postives = 199/295 (67.46%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M   L +YF+ +FE+K+L+KMP++E+D LT ATRLLEKRREM E++QAL+ QKEEF MK ESL QRR ELE KE +L++SL KFDKFL+END+K+ RAL KA EE+     KE E L+L+ E    ++ K  L E+ +K   +Q+YL+ V E +++F E++E+IDR+ TL  T + L+KRD E+ +L E +K +L   +E     +L+ N ++AQLQ  L++ R+ + + +  W  I  TAA  TL+ G+IRM+T NL+Q   K  R  +E +S ++ E QL KI    EDL+ I
Sbjct:    1 MEFDLGEYFRAAFEDKLLVKMPDREDDFLTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRAELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQLAAHKEREALRLQAENTQLMQRKGTLLERQEKNSKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQEETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQTISKQMRLKTE-ISVEDTEAQLEKIQICFEDLSAI 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Match: sp|Q6NTM6|CC42M_XENLA (Coiled-coil domain-containing protein 42 like-2 OS=Xenopus laevis OX=8355 PE=2 SV=2)

HSP 1 Score: 218.009 bits (554), Expect = 1.546e-67
Identity = 133/295 (45.08%), Postives = 200/295 (67.80%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M   L +YF+ +FE+K+L+KMP++E+D +T ATRLLEKRREM E++QAL+ QKEEF MK ESL QRR ELE KE +L++SL KFDKFL+END+K+ RAL KA EE+    QKE + L+L+ E    ++ K  L ++ +K  I+Q+YL+ V E +++F E++E+IDR+ TL  T + L+KR+ ++ +  E +K +L   +E     +L+ N ++AQLQ  L+++R+ + + +  W  I  TAA  TL+ G++RMAT NL+Q   K  R  ++ +S ++ E QL KI    EDL  I
Sbjct:    1 MEFDLGEYFRAAFEDKLLVKMPDREDDFMTPATRLLEKRREMVEVEQALSTQKEEFQMKSESLQQRRSELELKEEKLKDSLFKFDKFLKENDSKRKRALHKAAEERQMAAQKERDALRLQAENTQLMQRKHILLQRQEKNSIYQRYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRELKNQEHAEMEKARLLHYQEETRSQILELNNQIAQLQGELERARAVAFQWESRWAQIQNTAAENTLRLGRVRMATLNLFQTISKQMRLKTD-ISVEDTEAQLEKIQICFEDLAAI 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Match: sp|A6QQM8|CCD42_BOVIN (Coiled-coil domain-containing protein 42 OS=Bos taurus OX=9913 GN=CCDC42 PE=2 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 2.361e-51
Identity = 122/296 (41.22%), Postives = 181/296 (61.15%), Query Frame = 3

Query:   42 LDDYFKTSFEEKILI---KMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQS 920
            L +YF+  + E++L    K P  E+   + + RLLEK++E   +  A+  +KE F  ++E+L  R EEL  KE QL+  + KF++F+QEND K+ RALKKA +E+  KRQ+  E+ K K E+        +L+ KL++Y IF KYLE V E SE F EI E+I RY+TL +  H L++  +E  + IE  K +L+  KE K+  +LQ+N +LA+LQ   D++RS  +  +  W +I  TAA KTL  G I+MAT NL+QI  K Q   +  VS ++   QL  I +FI+DL+ I +
Sbjct:   11 LAEYFRLQYGERLLQLLQKFPSIEDQSDSPSVRLLEKKKEAKIMHHAMEQKKETFQRRMETLNLRWEELGIKEAQLKAHIQKFEQFIQENDQKRIRALKKANKERELKRQRMRELAKAKQEMAVLRLEHQRLSAKLQEYSIFNKYLEKVVENSE-FEEIHEVIARYKTLVSMHHDLMQSAQEGQEKIERAKARLARYKEEKDDEILQHNNELARLQMRFDRARSDVIIWESRWAHIQNTAAKKTLLLGTIKMATLNLFQIVSK-QLKEATFVSLEDTHKQLDMIQQFIQDLSDIWA 304

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Match: sp|A6NFT4|CFA73_HUMAN (Cilia- and flagella-associated protein 73 OS=Homo sapiens OX=9606 GN=CFAP73 PE=2 SV=3)

HSP 1 Score: 171.014 bits (432), Expect = 1.775e-49
Identity = 107/295 (36.27%), Postives = 180/295 (61.02%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M +  ++YF+ + +EK+  K+PE+  DH+    RLLEKR+E+ + DQAL AQKE F  K  +L QR E+LE+KE +L+ S ++FDKFLQ+++A++NRAL++A EE+    ++E+E L+L T++Q   +   +L  +LK+     + LE   E    F E+ E++ R++ L  T   L  R++E    +E  + +L   ++     VL    + AQLQ+ L+ +R ++L+ + +W  I  TAA KTL  G+ RMA  NL+Q+  ++Q  P   +  ++ EGQL  +  F++DL+ +
Sbjct:    1 MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPP-TLDIEDTEGQLEHVKLFMQDLSAM 294

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BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Match: H2Y4L5 (DUF4200 domain-containing protein OS=Ciona savignyi OX=51511 PE=4 SV=1)

HSP 1 Score: 285.034 bits (728), Expect = 2.296e-91
Identity = 156/295 (52.88%), Postives = 225/295 (76.27%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M + L+DYF+++FE+K+L+KMPE+E+DHLT ATRLLEKRREM+E++QAL AQKEEF MK+ESL QRREELERKE+QL+ESL+KFDKFL+END+K+ RA+KKA +E+  +R KE ++ +L+ +I+   K + +  +KL+K  IFQKY+E V E++++FSEIREII RY+TL  T   L+KRD ++ D IE +K +L    E KN  +L YN +LAQLQ  LD+++S++++ + +WT+I  TAA KTL  G+I++AT+NL+Q+  K+ +  +  V  +N   QL KI  FI+DL+ I
Sbjct:    1 MTVNLEDYFRSTFEDKLLVKMPEREDDHLTPATRLLEKRREMAEVEQALTAQKEEFQMKMESLQQRREELERKEHQLKESLLKFDKFLKENDSKRARAIKKAQDERELRRSKEKDIGRLQDDIERLSKERGRYQKKLEKNSIFQKYMERVQESTDEFSEIREIIGRYDTLVATHVDLMKRDLKNQDAIEEEKGRLVKFTEEKNNEILSYNNQLAQLQTRLDQAQSKAVKWESKWTHIQNTAAKKTLLLGRIKIATHNLFQLVNKHLKQQA-TVPLENTALQLDKIQMFIQDLSQI 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Match: A0A433TNK8 (DUF4200 domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_009065 PE=4 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 1.557e-89
Identity = 156/297 (52.53%), Postives = 222/297 (74.75%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQS 920
            M + L++YF+T+FE+K+L+KMPE+E+DHLT ATRLLEKRREM+E++QAL AQKEEF MK+ESL QRREELERKE QL+ESL+KFDKFL+END+K+ RA+KKA +E+  KRQK+ E+ ++K E   HLK K+ L +KL+KY IF  +++ V EA EDF EIR+II R++TL  T   L++ ++++ D +ENQ+Q+L    E K   VL YN +L+ LQ  LD ++S++++ +  WT+I  TAA KTL  G+I+MAT+NLYQ+ K +Q    E+   ++   QL +I +F++DL  I S
Sbjct:    1 MTVSLEEYFRTTFEDKLLVKMPEREDDHLTPATRLLEKRREMAEVEQALAAQKEEFQMKMESLQQRREELERKEFQLKESLLKFDKFLKENDSKRARAVKKANDERELKRQKDREIERVKQETAQHLKQKEALGKKLEKYTIFHTFMDKVQEAGEDFHEIRDIITRWDTLNATHTDLLETEQKNQDRVENQRQELMKYMEEKENQVLNYNNQLSGLQTRLDAAQSEAVKWESRWTHIKNTAAKKTLLLGRIKMATHNLYQLVKSHQNQTDEL---EDTTEQLTQIQQFVQDLNQITS 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Match: A0A1W2WBP4 (coiled-coil domain-containing protein 42 homolog OS=Ciona intestinalis OX=7719 GN=LOC100184539 PE=4 SV=1)

HSP 1 Score: 278.87 bits (712), Expect = 5.325e-89
Identity = 154/295 (52.20%), Postives = 225/295 (76.27%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M + L+DYF+++FE+K+L+KMPE+E+DHLT ATRLLEKRREM+E++QAL AQKEEF MK+ESL QRREELERKE+QL+ESL+KFDKFL+END+K+ RA+KKA +E+  +R KE ++ +L+ +I+   K +++  +KL+K  IFQKY+E V E++++FSEIREII RY+TL  T   L+KRD ++ D IE +K +L    E K+  +L YN +LAQ+Q  LD+++S++++ + +WT+I  TAA KTL  G+I++AT NL+Q+  K+ +  +  V  +N   QL KI  FI+DL+ I
Sbjct:    1 MTVNLEDYFRSTFEDKLLVKMPEREDDHLTPATRLLEKRREMAEVEQALTAQKEEFQMKMESLQQRREELERKEHQLKESLLKFDKFLKENDSKRARAIKKAHDERELRRGKEKDIERLQEDIERLSKERERYQKKLEKNSIFQKYMERVQESTDEFSEIREIIGRYDTLVATHVDLMKRDLKNQDAIEEEKGRLVKFTEEKSNEILYYNNQLAQMQTRLDQAQSKAVKWESKWTHIQNTAAKKTLLLGQIKIATLNLFQLVNKHLKQQA-TVPIENTSLQLDKIQMFIQDLSQI 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Match: A0A2C9K6J4 (DUF4200 domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106053244 PE=4 SV=1)

HSP 1 Score: 277.715 bits (709), Expect = 1.493e-88
Identity = 153/297 (51.52%), Postives = 222/297 (74.75%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQS 920
            M + L++YF+T+FE+K+L+KMPE+E+DHLT ATRLLEKRREM+E++QAL AQKEEF MK+ESL QRREELERKE QL+ESL+KFDKFL+END+K+ RA+KKA +E+  K+QK+ E+ ++K E + + K K+ L +K++KY IF  Y++ V EA EDF EIR+II R++TLT T   L++RD+ + + +E Q+Q L    E K   VL YN +L+ LQ  LD ++S++++ + +WT+I  TAA KTL  G+I+MAT+NLYQ+ + +Q    +V   ++   QL++I  F++DL  I S
Sbjct:    1 MTVSLEEYFRTTFEDKLLVKMPEREDDHLTPATRLLEKRREMAEVEQALAAQKEEFQMKMESLQQRREELERKEFQLKESLLKFDKFLKENDSKRARAVKKANDERELKKQKDKEIERVKEETEAYQKQKEMLQKKVEKYVIFHNYMDKVLEAGEDFHEIRDIITRWDTLTATHQDLLERDQLNHEKVEKQRQDLMKYMEEKENQVLNYNNQLSTLQTRLDAAQSEAVKWESKWTHIKNTAAKKTLLLGRIKMATHNLYQLVRSHQNQLDDV---EDTTEQLIQIQLFVQDLNQITS 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Match: A0A1S3H6L6 (coiled-coil domain-containing protein 42 homolog OS=Lingula unguis OX=7574 GN=LOC106152551 PE=4 SV=1)

HSP 1 Score: 276.559 bits (706), Expect = 5.036e-88
Identity = 158/295 (53.56%), Postives = 220/295 (74.58%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            M + L++YF T+FE+K+L+KMPE+E+DHLT ATRLLEKRREM+E++QAL AQKEEF MK+ESL QRREELERKE QL+E+L+KFDKFL+END+K++RA+KKA +E   ++QKE ++ KL+ E     K ++KL  KL+K+ IFQKYL+ V E SE+FSEIRE+I RY TLT T   L++RD+ + + IE  +Q L    E K+  +L YN +L+ LQ  LDK++S +++ + +WT+I  TAA KTL  G+I+MAT+NL+ +  K+Q+     ++ D  E QL KI  FI+DLT I
Sbjct:    1 MTVNLEEYFATTFEDKLLVKMPEREDDHLTPATRLLEKRREMAEVEQALAAQKEEFQMKMESLQQRREELERKEFQLKEALLKFDKFLKENDSKRSRAVKKANDEIDLRKQKEKDIDKLREETSEFAKQREKLQTKLEKHVIFQKYLDKVLETSEEFSEIREVIARYATLTATHEDLLERDQANQEKIEKMRQDLMKYTEDKHNEILGYNNRLSSLQTRLDKAQSAAVKWESKWTHIKNTAAKKTLILGQIKMATHNLFMLVNKHQKQGQTEMTEDTNE-QLNKIQTFIQDLTQI 294

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 160.614 bits (405), Expect = 1.967e-46
Identity = 118/310 (38.06%), Postives = 180/310 (58.06%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQSRADDSIENIAKDL 959
            M + L++YF+T FEE  L  +P  E D  T  TR+L+KRRE+  +D  L  QKEEF  K +SL QRR+EL +KE +L++SL+ F+K+L++NDAK+ R LKKA  EK   R++E EV +L+  I   L  K+K+ +++ +  I+  +L++V ++S+ F +I + I R+ETL      L+KR        E +  +L      ++  +L YN  L+QLQ  LD   SQ+L  +  W +I  TAA +TL  G+I++ T NLY +  +     +E  + D+   QL +I        YIQ RAD     I +DL
Sbjct:    1 MAVNLEEYFRTVFEEH-LQTVPMPEEDLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTILSQALRWESTWNHIQATAAKETLLLGQIKIVTLNLYHMTGRVT-SGAEGFNVDDTLDQLDRIQ------LYIQKRAD-----IVRDL 297

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 154.451 bits (389), Expect = 2.904e-44
Identity = 104/264 (39.39%), Postives = 161/264 (60.98%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKK 821
            M + L++YF+T FEE  L  +P  E D  T  TR+L+KRRE+  +D  L  QKEEF  K +SL QRR+EL +KE +L++SL+ F+K+L++NDAK+ R LKKA  EK   R++E EV +L+  I   L  K+K+ +++ +  I+  +L++V ++S+ F +I + I R+ETL      L+KR        E +  +L      ++  +L YN  L+QLQ  LD   SQ+L  +  W +I  TAA +TL  G+I++ T NLY +  +
Sbjct:    1 MAVNLEEYFRTVFEEH-LQTVPMPEEDLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTILSQALRWESTWNHIQATAAKETLLLGQIKIVTLNLYHMTGR 263

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Match: cfap73 (coiled-coil domain-containing protein 42 homolog [Source:NCBI gene;Acc:103032501])

HSP 1 Score: 127.872 bits (320), Expect = 1.273e-34
Identity = 93/241 (38.59%), Postives = 150/241 (62.24%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKI-LIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRT 749
            M + L++YF+T FEE +  + MPE+  D  T  TR+L+KRRE+  +D  L  QKEEF  K +SL QRR+EL +KE +L++SL+ F+K+L++NDAK+ R LKKA  EK   R++E EV +L+  I   L  K+K+ +++ +  I+  +L++V ++S+ F +I + I R+ETL      L+KR        E +  +L      ++  +L YN  L+QLQ  LD   SQ+L + V+  +I+++
Sbjct:    1 MAVNLEEYFRTVFEEHLQTVPMPEE--DLRTGTTRILDKRREIKYMDDVLRNQKEEFEAKKKSLEQRRDELRKKEEKLKDSLLNFNKYLKDNDAKQARGLKKAEAEKALVREREKEVQQLQRHIAALLTKKEKMQKRVSQKRIYWSFLDSVLKSSKKFEDIGKFIGRFETLVCMREQLLKRQSTVESEREREAVQLRRYVSERSSALLHYNNTLSQLQTELDTILSQAL-RWVQPVSILKS 238

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Match: si:ch1073-416d2.4 (si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121-564])

HSP 1 Score: 55.0694 bits (131), Expect = 4.078e-8
Identity = 83/292 (28.42%), Postives = 148/292 (50.68%), Query Frame = 3

Query:  126 TRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHH---XXXXXXXXXXXXXYYIFQKYLETVTEASEDFSE------IREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASK--TLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLL--KISRFIEDLTYIQSRA---DDSIENIAK 953
            T LL+K+ ++ E++  L  ++ EF  +++ L +RR EL     Q ++  +KF+KF++EN+ K+ RALKK   E+    QKE E    K+E+  H   L+I   L ++++KY ++++YL  + +   ++ E         II R+ETL+ T   LV+      + +E  ++ L   K+  N + L  N ++++LQ   D+ + ++  K +E T  I    ++    + G + +A  NL Q     Q H     S D+++   +   I  FI D   ++ RA    DS   I K
Sbjct:   35 TLLLKKQLKVDEVNTELKQKQLEFRARMQILEKRRAEL----LQTKDRAVKFEKFVEENEVKRRRALKKYQVERKQNEQKEKE----KSELCEHFDQLQIHQYLKQRVEKYKMYEEYLRKILDLLPEYLEYGSDSLAMPIIRRHETLSITQQTLVQHLTGLSEELEQGQRNLDSLKQEHNTSKLMINKEMSELQTQWDQIKEKN--KQLEMTLQIHQGQNRDQAEEIGSLMIAVKNLGQ-----QCHLQHYGSLDDMKMLTMMDMIMEFILDKADLERRAMRLTDSGSEITK 311

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000003941.2 (pep primary_assembly:Astyanax_mexicanus-2.0:3:67849880:67853480:-1 gene:ENSAMXG00000003857.2 transcript:ENSAMXT00000003941.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 6.865e-7
Identity = 37/121 (30.58%), Postives = 65/121 (53.72%), Query Frame = 3

Query:  453 IFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIA 815
            I+   L++V ++S++F +  ++I R++TL  T   L+KR        E +  +L      +   +  Y   L+QLQ  L+ +RSQ+   +    +I +T A +TL  G+I +AT NLYQ+ 
Sbjct:   64 IYWSLLDSVLKSSDEFEDFGKLIGRFKTLVRTKEQLLKRQSTMESEREREAVQLRQYVSERRSLLQHYENTLSQLQTELNTTRSQARRLESTEKHIQKTDAKRTLLLGRIHVATRNLYQMT 184

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Nematostella
Match: EDO39885 (Coiled-coil domain-containing protein 42 homolog [Source:UniProtKB/Swiss-Prot;Acc:A7S8T5])

HSP 1 Score: 278.485 bits (711), Expect = 1.099e-92
Identity = 161/306 (52.61%), Postives = 224/306 (73.20%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQ---SRADDSI 938
            M + L++YF+T+FE+K+L+KMPE+E+DHLT ATRLLEKRREMSE++QAL AQKEEF MK+ESL QRREELERKE QLRESL+KFDKFL+END+K+ RALKKA EE+  +R K+ E+ +LK +    +K +DK+  +L+KY I+Q+YLE V E +E+F EIREII RY+TLT T   L++R+ ++ +  E +K +L    E KN  +L YN +LA LQ  L+K++S +++ + +WT+I  TAA KTL  G+I+MAT+NL+ +     RH  +    D  + QL KI  FI+DLT I     RA+++I
Sbjct:    1 MTVNLEEYFRTTFEDKLLVKMPEREDDHLTPATRLLEKRREMSEVEQALGAQKEEFQMKMESLQQRREELERKEYQLRESLLKFDKFLKENDSKRARALKKAQEERDMRRAKDCEIARLKEDTSGLMKGRDKVQHRLEKYIIYQQYLEKVLENAEEFQEIREIIARYDTLTATHQDLLERELKNQEKYEKEKARLIKFTEEKNNEILNYNNQLANLQTKLEKTQSVAVKWESQWTHIKNTAAKKTLLLGRIKMATHNLFMLV---NRHLGQTGMVDMTDKQLDKIQVFIQDLTQITLDIKRAENAI 303

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Nematostella
Match: EDO38155 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDR1])

HSP 1 Score: 63.929 bits (154), Expect = 1.834e-11
Identity = 55/163 (33.74%), Postives = 92/163 (56.44%), Query Frame = 3

Query:  252 NQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTE-ASEDF-----SEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKD 722
            N++R+ + KF+KF++EN+AK+ RA++K   E   K QK  E   L  E+Q     K  L  K+ KY +++KYL  V +   ED+     S +  I+ R+ TL+ T H L++   +  D +E  +QKL D      Q ++  N +LA LQ++L+++  ++ E D
Sbjct:   40 NEIRDRVGKFEKFIKENEAKRRRAVQKYQTELKLKDQKSKEEEILAAELQQLKARKHSLEAKIAKYSVYEKYLLKVLDFLPEDYLEASDSMLMGIMMRFRTLSATNHTLMQMLSDKADGVEQSQQKLLDMNNNHTQHLVLINSELAHLQQILEETSQKNAELD 202

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Match: SMESG000046807.1 (SMESG000046807.1)

HSP 1 Score: 539.265 bits (1388), Expect = 0.000e+0
Identity = 283/284 (99.65%), Postives = 284/284 (100.00%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLK 881
            MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEV+SYDNIEGQLLK
Sbjct:    1 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVISYDNIEGQLLK 284

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Match: SMESG000046807.1 (SMESG000046807.1)

HSP 1 Score: 529.635 bits (1363), Expect = 0.000e+0
Identity = 285/311 (91.64%), Postives = 286/311 (91.96%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQSRADDSIENIAKDLE 962
            MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFH                         VKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEV+SYDNIEGQLLKISRFIEDLTYIQSRADDSIENIAKDLE
Sbjct:    1 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFH-------------------------VKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVISYDNIEGQLLKISRFIEDLTYIQSRADDSIENIAKDLE 286

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 246.899 bits (629), Expect = 4.025e-80
Identity = 145/284 (51.06%), Postives = 199/284 (70.07%), Query Frame = 3

Query:   63 SFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            +FEEK LIK+PEKEND LT ATRLLEKRREM EID+A   QKEEF MK+ES  QR+ +LE+KE QL ESL++F+KFL+EN++KKNRA++KA+ E+ N+R K  E+L+L   +  + K ++ L  KL+KY  +Q Y+E V E SE+FSEIRE+IDR+ TL +T+  L++RD+ +   +  +K  L   KE +N  ++QYN +  QLQ  LD+ +S +LEK  EW ++I +AA KTL  GKI+MAT NLY I++K+     +     +I  QL KI  F EDL YI
Sbjct:    8 NFEEKFLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 291

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Match: SMESG000073880.1 (SMESG000073880.1)

HSP 1 Score: 246.514 bits (628), Expect = 4.776e-80
Identity = 145/284 (51.06%), Postives = 199/284 (70.07%), Query Frame = 3

Query:   63 SFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYI 914
            +FEEK LIK+PEKEND LT ATRLLEKRREM EID+A   QKEEF MK+ES  QR+ +LE+KE QL ESL++F+KFL+EN++KKNRA++KA+ E+ N+R K  E+L+L   +  + K ++ L  KL+KY  +Q Y+E V E SE+FSEIRE+IDR+ TL +T+  L++RD+ +   +  +K  L   KE +N  ++QYN +  QLQ  LD+ +S +LEK  EW ++I +AA KTL  GKI+MAT NLY I++K+     +     +I  QL KI  F EDL YI
Sbjct:   10 NFEEKFLIKIPEKENDSLTVATRLLEKRREMHEIDEAFQYQKEEFKMKMESFQQRKFDLEKKELQLSESLLRFNKFLKENESKKNRAIQKAILERENQRNKSKEILELTKLLGDYQKKQETLRLKLEKYRWYQHYIENVIEMSEEFSEIREVIDRFSTLRSTYEDLLERDRNNQMQLNEEKHNLMQLKENRNGQIIQYNNRQGQLQLELDRLQSITLEKSAEWNSLISSAARKTLSYGKIKMATNNLYIISQKFFGKKIKSTKLVDILKQLDKIQNFFEDLNYI 293

[Close]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Match: SMESG000046807.1 (SMESG000046807.1)

HSP 1 Score: 250.751 bits (639), Expect = 7.070e-80
Identity = 140/168 (83.33%), Postives = 143/168 (85.12%), Query Frame = 3

Query:  378 LKLKTEIQHHXXXXXXXXXXXXXYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKEVKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLK 881
            ++LKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFH                         VKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEV+SYDNIEGQLLK
Sbjct:  229 VRLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETVTEASEDFSEIREIIDRYETLTTTFH-------------------------VKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGKIRMATYNLYQIAKKYQRHPSEVISYDNIEGQLLK 371

HSP 2 Score: 233.032 bits (593), Expect = 5.389e-73
Identity = 118/119 (99.16%), Postives = 119/119 (100.00%), Query Frame = 3

Query:   30 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKL 386
            MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLK+
Sbjct:    1 MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALNAQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALKKALEEKTNKRQKELEVLKM 119

The following BLAST results are available for this feature:

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Celegans
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Fly
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Zebrafish
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Xenopus
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Sea Lamprey
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Yeast
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Nematostella
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Medaka
BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4


Match Name	E-value	Identity	Description
CFAP73	3.696e-50	36.27	cilia and flagella associated protein 73 [Source:H...	[more]
CCDC42	2.600e-45	39.19	coiled-coil domain containing 42 [Source:HGNC Symb...	[more]
CCDC42	1.779e-16	39.35	coiled-coil domain containing 42 [Source:HGNC Symb...	[more]
CFAP73	7.453e-8	36.76	cilia and flagella associated protein 73 [Source:H...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
cfap73	1.216e-28	36.49	cilia and flagella associated protein 73 [Source:Z...	[more]
si:ch1073-416d2.4	1.611e-9	28.93	si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121...	[more]
si:ch1073-416d2.4	1.136e-7	31.03	si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
klhl13	1.968e-69	46.78	kelch like family member 13 [Source:Xenbase;Acc:XB...	[more]
klhl13	5.886e-67	46.81	kelch like family member 13 [Source:Xenbase;Acc:XB...	[more]
cfap73	2.739e-13	27.08	cilia and flagella associated protein 73 [Source:X...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Ccdc42	3.620e-49	41.16	coiled-coil domain containing 42 [Source:MGI Symbo...	[more]
Cfap73	1.398e-32	30.03	cilia and flagella associated protein 73 [Source:M...	[more]
Ccdc42	4.158e-22	41.13	coiled-coil domain containing 42 [Source:MGI Symbo...	[more]
Ccdc42	2.970e-18	40.65	coiled-coil domain containing 42 [Source:MGI Symbo...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|A7S8T5\|CCD42_NEMVE	2.682e-91	52.61	Coiled-coil domain-containing protein 42 homolog O...	[more]
sp\|B0BMJ2\|CC42M_XENTR	1.042e-68	46.78	Coiled-coil domain-containing protein 42 like-2 OS...	[more]
sp\|Q6NTM6\|CC42M_XENLA	1.546e-67	45.08	Coiled-coil domain-containing protein 42 like-2 OS...	[more]
sp\|A6QQM8\|CCD42_BOVIN	2.361e-51	41.22	Coiled-coil domain-containing protein 42 OS=Bos ta...	[more]
sp\|A6NFT4\|CFA73_HUMAN	1.775e-49	36.27	Cilia- and flagella-associated protein 73 OS=Homo ...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H2Y4L5	2.296e-91	52.88	DUF4200 domain-containing protein OS=Ciona savigny...	[more]
A0A433TNK8	1.557e-89	52.53	DUF4200 domain-containing protein OS=Elysia chloro...	[more]
A0A1W2WBP4	5.325e-89	52.20	coiled-coil domain-containing protein 42 homolog O...	[more]
A0A2C9K6J4	1.493e-88	51.52	DUF4200 domain-containing protein OS=Biomphalaria ...	[more]
A0A1S3H6L6	5.036e-88	53.56	coiled-coil domain-containing protein 42 homolog O...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cfap73	1.967e-46	38.06	coiled-coil domain-containing protein 42 homolog [...	[more]
cfap73	2.904e-44	39.39	coiled-coil domain-containing protein 42 homolog [...	[more]
cfap73	1.273e-34	38.59	coiled-coil domain-containing protein 42 homolog [...	[more]
si:ch1073-416d2.4	4.078e-8	28.42	si:ch1073-416d2.4 [Source:ZFIN;Acc:ZDB-GENE-131121...	[more]
ENSAMXT00000003941.2	6.865e-7	30.58	pep primary_assembly:Astyanax_mexicanus-2.0:3:6784...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO39885	1.099e-92	52.61	Coiled-coil domain-containing protein 42 homolog ...	[more]
EDO38155	1.834e-11	33.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Coiled-coil domain-containing protein 42-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000046807.1	0.000e+0	99.65	SMESG000046807.1	[more]
SMESG000046807.1	0.000e+0	91.64	SMESG000046807.1	[more]
SMESG000073880.1	4.025e-80	51.06	SMESG000073880.1	[more]
SMESG000073880.1	4.776e-80	51.06	SMESG000073880.1	[more]
SMESG000046807.1	7.070e-80	83.33	SMESG000046807.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000840 ID=SMED30000840|Name=Coiled-coil domain-containing protein 42-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1029bp
CGAAATCTGTATAAATCTTATATGTAAAAATGAATCTGTATCTGGACGAT
TATTTTAAAACTTCTTTTGAAGAGAAAATACTGATAAAAATGCCAGAAAA
GGAAAATGATCATTTAACCAACGCAACAAGATTATTAGAAAAGAGAAGAG
AAATGAGTGAAATCGATCAGGCATTGAATGCTCAAAAAGAGGAATTTCAC
ATGAAAATCGAAAGTTTGACTCAAAGAAGAGAGGAATTAGAAAGAAAAGA
AAACCAGTTGAGAGAATCTCTGATGAAATTTGACAAATTTCTTCAAGAAA
ATGACGCAAAGAAAAATCGAGCTTTGAAAAAAGCCTTAGAAGAAAAGACC
AATAAACGCCAGAAGGAATTAGAAGTGCTTAAATTGAAAACAGAAATTCA
ACATCATTTGAAAATTAAAGACAAACTTAACGAAAAACTCAAAAAATATT
ATATTTTCCAAAAATATCTAGAAACCGTAACGGAAGCTTCTGAAGATTTT
AGTGAAATTCGAGAAATCATAGATCGTTATGAAACTTTGACCACAACTTT
TCATTATTTGGTGAAACGCGACAAAGAAGATTTTGATTTGATTGAGAATC
AAAAACAAAAACTATCGGATGGAAAAGAAGTTAAAAATCAAACAGTTCTC
CAATACAACATAAAATTGGCCCAATTACAAAAAATGTTGGACAAGTCAAG
ATCTCAGTCATTGGAAAAAGATGTTGAATGGACAAACATAATACGCACTG
CAGCTTCGAAAACATTGAAATGTGGCAAAATAAGAATGGCAACGTATAAT
CTTTATCAGATAGCTAAAAAATATCAGCGTCATCCTTCAGAAGTTGTTTC
TTATGATAACATTGAAGGACAGCTATTAAAAATATCAAGATTTATTGAGG
ATTTGACATATATCCAAAGCAGGGCTGACGACAGTATTGAAAATATTGCT
AAGGATTTAGAATAATTTTAAAATATTCTTTATTTTCTATTTATTTATAA
AATTTTTATTGATTTTGAAAGCTCACTTC

protein sequence of SMED30000840-orf-1

>SMED30000840-orf-1 ID=SMED30000840-orf-1|Name=SMED30000840-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=312bp
MNLYLDDYFKTSFEEKILIKMPEKENDHLTNATRLLEKRREMSEIDQALN
AQKEEFHMKIESLTQRREELERKENQLRESLMKFDKFLQENDAKKNRALK
KALEEKTNKRQKELEVLKLKTEIQHHLKIKDKLNEKLKKYYIFQKYLETV
TEASEDFSEIREIIDRYETLTTTFHYLVKRDKEDFDLIENQKQKLSDGKE
VKNQTVLQYNIKLAQLQKMLDKSRSQSLEKDVEWTNIIRTAASKTLKCGK
IRMATYNLYQIAKKYQRHPSEVVSYDNIEGQLLKISRFIEDLTYIQSRAD
DSIENIAKDLE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000418	head
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR025252	DUF4200

Vocabulary: **biological process**
Term	Definition
GO:0007286	spermatid development

Main menu

Coiled-coil domain-containing protein 42-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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