Leucine-rich repeat-containing protein 45

Overview


Name	Leucine-rich repeat-containing protein 45
Smed ID	SMED30000732
Length (bp)	2262

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Leucine-rich repeat-containing protein 45 (SMED30000732) t-SNE clustered cells

Violin plots show distribution of expression levels for Leucine-rich repeat-containing protein 45 (SMED30000732) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leucine-rich repeat-containing protein 45 (SMED30000732) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Leucine-rich repeat-containing protein 45 (SMED30000732) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30000732

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30000732	h1SMcG0002787	Contig3762	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000732	h1SMcG0002787	Contig3762	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000732	h1SMcG0014491	Contig3762	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30000732	h1SMcG0014491	Contig3762	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
head region	SMED30000732	h1SMcG0002787	SmedASXL_013987	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30000732	h1SMcG0002787	dd_Smed_v6_9495_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
reproductive organ	SMED30000732	h1SMcG0002787	Contig29080	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30000732	h1SMcG0002787	Contig29080	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30000732	h1SMcG0002787	dd_Smed_v4_9495_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Match: LRRC45 (leucine rich repeat containing 45 [Source:HGNC Symbol;Acc:HGNC:28302])

HSP 1 Score: 265.388 bits (677), Expect = 7.083e-78
Identity = 199/673 (29.57%), Postives = 361/673 (53.64%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY---ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKD----KEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T   E+   DCMLS +   L+L GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  LQ LDLRNNQI     + L  AL+ NT L+ LD+R+N++G+ GG+ ++N    NRTL ++ + GNNIP D+++ +E     + +     + + +R+    K   +   E S+  Q LDL++ ID+Q   +  S + S +++ QL++ L+ER      L A L + E+ L + E + ++       + +E+  L ++   +L  E+    E E + L++ S   E+ L LQN+V ELE     Q   +F+ + ++T  ++E K + +  EE++    D  K+   + +E  +    KE+  M      +E+  +E++ + +  R  L +E+S +K    S+R Q +E++ K K +   E+ Q+++ L+++L+ +   +DE +    +Q + +   Q   S+L +++E L+ + E L++ELS K    ++E+ +VR+E   +  +L++E  +Q  L  K    ++Q++ M +  RE    R +E  +L+++L+ +E E+ R  ++E  RAS L NAV+ Y Q S
Sbjct:    1 MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGR------LDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSK--QFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERL----DMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQAS 661

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Match: NLRC3 (NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889])

HSP 1 Score: 76.2554 bits (186), Expect = 1.395e-13
Identity = 64/245 (26.12%), Postives = 98/245 (40.00%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQV--------------------------GISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
             N  L  L L   S+S      L      + T   +S ++  +SP+  Q I   L  N     L L  N + +QG  ++A  +  N T+T L L+WN +                           I   G       L  N  L  L L+   IG    Q+L EAL  N  L++LD+R N+IGV+G K + N  + N +L ++ +  N++ MD    I    + N  +   N + N   D   +
Sbjct:  804 VNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGAR 1048

HSP 2 Score: 68.9366 bits (167), Expect = 2.841e-11
Identity = 53/178 (29.78%), Postives = 90/178 (50.56%), Query Frame = 1

Query:  253 FKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            F+D ++  + L  +L G   +C   K+ L  N I N+G ++LAR +  N ++T L L  N +G  G       + L  N+TL  L L+ N +  D  + + EAL  N  L +L ++ NSIG  G + + +  ++NR+L +++   N+I     K +      N  +   + +SNS SD
Sbjct:  649 FQDPVM--ELLGSVLSG--KDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGA--KALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISD 820

HSP 3 Score: 68.9366 bits (167), Expect = 2.866e-11
Identity = 49/208 (23.56%), Postives = 102/208 (49.04%), Query Frame = 1

Query:  103 DFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIEN 726
            D +++ + S     + ++  ++L+E  +S +  K L+     + +   +  +   + P   + + + L  N     L L+GN +++ G  S+A  ++ N T++ L L+ N +G  G    +  + L  N++L+ L   +N IG    + L EAL+ N  L+ LD++ NSI  +G   ++     N+TL  + +  N+I  +  + I +
Sbjct:  651 DPVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGA--QRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAH 856

HSP 4 Score: 60.4622 bits (145), Expect = 1.186e-8
Identity = 47/177 (26.55%), Postives = 78/177 (44.07%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            N  L  L+L   ++  +  + ++E    + T   +  +   + P   Q + + L  N    +L    N+I + G ++LA  +  N  +  L L+ N   IS  G       L  N+TL  L LR N I  +  Q +  AL  N+ LK LD+  N +   G + I     +NRTL+ +
Sbjct:  721 NRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNS--ISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSL 895

HSP 5 Score: 55.4546 bits (132), Expect = 4.441e-7
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 1

Query:  322 CIKLCLKGNNIKNQGCESLARLIS-RNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI-PMDIIKNIENLANRNGEISEANERSNSRSDRNGK--RNNYENSRKLQTLDL 843
            C KL L  N  ++   E L  ++S ++  I  +SL  NQ  IS  G       L+ N++L  LDLR N IG    + L +AL+ N  L  L ++ N++   G + +      NRTLS + +  N+I PM   +  + L  +N  + E    SNS  D   K      + ++ L++LDL
Sbjct:  639 CRKLRLDTNQFQDPVMELLGSVLSGKDCRIQKISLAENQ--ISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADAL-KQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDL 813

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Match: NLRC3 (NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889])

HSP 1 Score: 76.2554 bits (186), Expect = 1.727e-13
Identity = 64/245 (26.12%), Postives = 98/245 (40.00%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQV--------------------------GISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
             N  L  L L   S+S      L      + T   +S ++  +SP+  Q I   L  N     L L  N + +QG  ++A  +  N T+T L L+WN +                           I   G       L  N  L  L L+   IG    Q+L EAL  N  L++LD+R N+IGV+G K + N  + N +L ++ +  N++ MD    I    + N  +   N + N   D   +
Sbjct:  851 VNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGAR 1095

HSP 2 Score: 68.9366 bits (167), Expect = 2.787e-11
Identity = 48/198 (24.24%), Postives = 98/198 (49.49%), Query Frame = 1

Query:  103 DFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            D +++ + S     + ++  ++L+E  +S +  K L+     + +   +  +   + P   + + + L  N     L L+GN +++ G  S+A  ++ N T++ L L+ N +G  G    +  + L  N++L+ L   +N IG    + L EAL+ N  L+ LD++ NSI  +G   ++     N+TL  + +  N+I
Sbjct:  698 DPVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGA--QRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSI 893

HSP 3 Score: 68.9366 bits (167), Expect = 2.835e-11
Identity = 53/178 (29.78%), Postives = 90/178 (50.56%), Query Frame = 1

Query:  253 FKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            F+D ++  + L  +L G   +C   K+ L  N I N+G ++LAR +  N ++T L L  N +G  G       + L  N+TL  L L+ N +  D  + + EAL  N  L +L ++ NSIG  G + + +  ++NR+L +++   N+I     K +      N  +   + +SNS SD
Sbjct:  696 FQDPVM--ELLGSVLSG--KDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGA--KALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISD 867

HSP 4 Score: 60.4622 bits (145), Expect = 1.180e-8
Identity = 47/177 (26.55%), Postives = 78/177 (44.07%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            N  L  L+L   ++  +  + ++E    + T   +  +   + P   Q + + L  N    +L    N+I + G ++LA  +  N  +  L L+ N   IS  G       L  N+TL  L LR N I  +  Q +  AL  N+ LK LD+  N +   G + I     +NRTL+ +
Sbjct:  768 NRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNS--ISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSL 942

HSP 5 Score: 55.0694 bits (131), Expect = 4.846e-7
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 1

Query:  322 CIKLCLKGNNIKNQGCESLARLIS-RNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI-PMDIIKNIENLANRNGEISEANERSNSRSDRNGK--RNNYENSRKLQTLDL 843
            C KL L  N  ++   E L  ++S ++  I  +SL  NQ  IS  G       L+ N++L  LDLR N IG    + L +AL+ N  L  L ++ N++   G + +      NRTLS + +  N+I PM   +  + L  +N  + E    SNS  D   K      + ++ L++LDL
Sbjct:  686 CRKLRLDTNQFQDPVMELLGSVLSGKDCRIQKISLAENQ--ISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADAL-KQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDL 860

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Match: LRRC74A (leucine rich repeat containing 74A [Source:HGNC Symbol;Acc:HGNC:23346])

HSP 1 Score: 67.781 bits (164), Expect = 4.414e-11
Identity = 58/200 (29.00%), Postives = 88/200 (44.00%), Query Frame = 1

Query:  109 IIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECF-RHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMD 705
            +++ +Q  Y+     L  + +S   +  E  +++S+ F R+ ++   +         D   L+ + LS N    KL L  N   + G E L ++++ N  +T L L WN     G      CNGL  N TL  LDL  N  G +    L E L+ N  L  LD+  N IG  G   I    E N +L  + +  N I MD
Sbjct:  153 LVEMLQENYY-----LQEMNISNNHLGLEGARIISDFFERNSSSIWSLELSGNDFKEDSAALLCQALSTNYQIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGA--VALCNGLRGNVTLTKLDLSMNGFGNEVALALGEVLRLNRCLVYLDIGGNDIGNEGASKISKGLESNESLRVLKLFLNPINMD 345

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Match: NLRC3 (NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889])

HSP 1 Score: 62.3882 bits (150), Expect = 2.104e-10
Identity = 39/133 (29.32%), Postives = 69/133 (51.88%), Query Frame = 1

Query:  268 LSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTL 666
            + P   + + + L  N     L L+GN +++ G  S+A  ++ N T++ L L+ N +G    G  +  + L  N++L+ L   +N IG    + L EAL+ N  L+ LD++ NSI  +G   ++     N+TL
Sbjct:    7 IGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGP--MGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTL 137

HSP 2 Score: 56.9954 bits (136), Expect = 1.279e-8
Identity = 42/156 (26.92%), Postives = 70/156 (44.87%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSI 612
            N  L  L+L   ++  +  + ++E    + T   +  +   + P   Q + + L  N    +L    N+I + G ++LA  +  N  +  L L+ N   IS  G       L  N+TL  L LR N I  +  Q +  AL  N+ LK LD+++N I
Sbjct:   22 NRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNS--ISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLQWNFI 175

HSP 3 Score: 53.5286 bits (127), Expect = 2.005e-7
Identity = 43/162 (26.54%), Postives = 72/162 (44.44%), Query Frame = 1

Query:  181 SMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTL 666
            S+  +  K L++  + + T   +S +   +  D  + + E L+ N     L L+ N+I   G + +A  + +N ++ +L    N +G  G         L  N+ L+ LDL++N I       L  AL  N  L  L +R NSI   G + I +    N TL
Sbjct:    6 SIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGA--KALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTL 165

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Match: lrrc45 (leucine rich repeat containing 45 [Source:ZFIN;Acc:ZDB-GENE-121214-317])

HSP 1 Score: 310.071 bits (793), Expect = 9.884e-95
Identity = 219/676 (32.40%), Postives = 387/676 (57.25%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY---ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKE-NDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+F+  +L LCK+  +   + ++  +      T S    L LS +S++ + C VL+   ++DT F EI   DCMLS + ++++L GL  N     L LKGNN++  G E+L +L+ RN  +  L LEWN +G+   GF  FC GL ++ +L  LDLRNNQI       L  AL++N+NL+ LD+R+N++G+ GG+ +L   ++NRTL+K+ + GNNIP D ++ IE   N N +       S SR+    K       E SR  Q L L++ ID Q   +  S + S  ++ QL++ L+E+K     L A L + E+ L + E +  +  D   +  +++ E  ERQ   ++ KE +     E + LKE ++L E+ LQL++K+ E E     Q + +FELK ++T T +E K ++   EE++   K + K+ + ++   + KE++ +      +E   +E+++K +  R +L +E+S +K  + ++R Q +E++ K++ ++  E+ Q ++ L+E+L+ ++  +DE ++   +Q + I  L    S+  IE +SL+ + + L+++L+GK+   +SE+ +VR+E   +I  L++ER +Q  L  KI   +++I+ +  + RE    + +EM +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S  + F+
Sbjct:    1 MEDFRRSYLRLCKEGGVDTQESVLAQLHDTRTVTGSSR--LDLSGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHNVDRQSTLRESKSRTQVLSKEIQLLKDEKSR--QYLSLMETIDRQKGEMGRSSRNSSIRLGQLQEALNEQKSSVNSLTAKLQMTEAALALSEQKNHDLADLLTRVKMEKNELRERQSR-EIKKEHEENAVREAKHLKEVNSLSEKNLQLRSKLEETERRCKTQQDQIFELKQELTNTTAELKLRLAQTEERLEMEKRRAKQALEDMDGLRQKEVDHLTRHQEDSERALQERILKLEGQRIQLEEELSRVKASLVTERAQAEEELGKVRSQVRLEEQQHLTSLEEKLRAVRQSRDESQNHCTQQKQTIAELHAKVSQQSIETDSLRRRIDELQQDLAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFS 671

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Match: lrrc45 (leucine rich repeat containing 45 [Source:ZFIN;Acc:ZDB-GENE-121214-317])

HSP 1 Score: 301.982 bits (772), Expect = 8.494e-92
Identity = 218/676 (32.25%), Postives = 387/676 (57.25%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY---ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKE-NDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+F+  +L LCK+  +   + ++           ++L  L LS +S++ + C VL+   ++DT F EI   DCMLS + ++++L GL  N     L LKGNN++  G E+L +L+ RN  +  L LEWN +G+   GF  FC GL ++ +L  LDLRNNQI       L  AL++N+NL+ LD+R+N++G+ GG+ +L   ++NRTL+K+ + GNNIP D ++ IE   N N +       S SR+    K       E SR  Q L L++ ID Q   +  S + S  ++ QL++ L+E+K     L A L + E+ L + E +  +  D   +  +++ E  ERQ   ++ KE +     E + LKE ++L E+ LQL++K+ E E     Q + +FELK ++T T +E K ++   EE++   K + K+ + ++   + KE++ +      +E   +E+++K +  R +L +E+S +K  + ++R Q +E++ K++ ++  E +Q ++ L+E+L+ ++  +DE ++   +Q + I  L    S+  IE +SL+ + + L+++L+GK+   +SE+ +VR+E   +I  L++ER +Q  L  KI   +++I+ +  + RE    + +EM +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S  + F+
Sbjct:    1 MEDFRRSYLRLCKEGGVDTQESVL-----------AQLSRLDLSGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHNVDRQSTLRESKSRTQVLSKEIQLLKDEKSR--QYLSLMETIDRQKGEMGRSSRNSSIRLGQLQEALNEQKSSVNSLTAKLQMTEAALALSEQKNHDLADLLTRVKMEKNELRERQSR-EIKKEHEENAVREAKHLKEVNSLSEKNLQLRSKLEETERRCKTQQDQIFELKQELTNTTAELKLRLAQTEERLEMEKRRAKQALEDMDGLRQKEVDHLTRHQEDSERALQERILKLEGQRIQLEEELSRVKASLVTERAQAEEELGKVRSQVRLE-EQHLTSLEEKLRAVRQSRDESQNHCTQQKQTIAELHAKVSQQSIETDSLRRRIDELQQDLAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFS 661

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Match: lrrc45 (leucine rich repeat containing 45 [Source:ZFIN;Acc:ZDB-GENE-121214-317])

HSP 1 Score: 298.901 bits (764), Expect = 8.343e-91
Identity = 217/676 (32.10%), Postives = 377/676 (55.77%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY---ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKE-NDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+F+  +L LCK+  +   + ++  +      T S    L LS +S++ + C VL+   ++DT F EI   DCMLS + ++++L GL  N     L LKGNN++  G E+L +L+ RN  +  L LEWN +G+   GF  FC GL ++ +L  LDLRNNQI       L  AL++N+NL+ LD+R+N++G+ GG+ +L   ++NRTL+K+ + GNNIP D ++ IE   N N +       S SR+    K       E SR  Q L L++ ID Q   +  S + S  ++ QL++ L+E+K     L A L + E+ L + E +  +  D   +  +++ E  ERQ  +  + E   R   E + LKE ++L E+ LQL++K+ E E     Q + +FELK ++T T +E K ++   E                     D+  +  RH+ + +E   +E+++K +  R +L +E+S +K  + ++R Q +E++ K++ ++  E+ Q ++ L+E+L+ ++  +DE ++   +Q + I  L    S+  IE +SL+ + + L+++L+GK+   +SE+ +VR+E   +I  L++ER +Q  L  KI   +++I+ +  + RE    + +EM +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S  + F+
Sbjct:    1 MEDFRRSYLRLCKEGGVDTQESVLAQLHDTRTVTGSSR--LDLSGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHNVDRQSTLRESKSRTQVLSKEIQLLKDEKSR--QYLSLMETIDRQKGEMGRSSRNSSIRLGQLQEALNEQKSSVNSLTAKLQMTEAALALSEQKNHDLADLLTRVKMEKNELRERQAGVLHNLENAVR---EAKHLKEVNSLSEKNLQLRSKLEETERRCKTQQDQIFELKQELTNTTAELKLRLAQTE--------------------GDRVDHLTRHQED-SERALQERILKLEGQRIQLEEELSRVKASLVTERAQAEEELGKVRSQVRLEEQQHLTSLEEKLRAVRQSRDESQNHCTQQKQTIAELHAKVSQQSIETDSLRRRIDELQQDLAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFS 648

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Match: lrrc45 (leucine rich repeat containing 45 [Source:ZFIN;Acc:ZDB-GENE-121214-317])

HSP 1 Score: 261.922 bits (668), Expect = 4.399e-77
Identity = 209/675 (30.96%), Postives = 373/675 (55.26%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQ---LEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+F+  +L L         + ++  +      T S    L LS +S++ + C VL+   ++DT F EI   DCMLS + ++++L GL  N     L LKGNN++  G E+L +L+ RN  +  L LEWN +G+   GF  FC GL ++ +L  LDLRNNQI       L  AL++N+NL+ LD+R+N++G+ GG+ +L   ++NRTL+K+ + GNNIP D ++ IE   N N +       S SR+           S+++Q L      DE++  +R+S       II    L++ L+E+K     L A L + E+ L + E   K +D +    L  R  +E+    +L + +   I+ E   LKE ++L E+ LQL++K+ E E     Q + +FELK ++T T +E K ++   EE++   K + K+ + ++   + KE+  +    +     +++ L+   +  + +  E+S +K  + ++R Q +E++ K++ ++  E+ Q ++ L+E+L+ ++  +DE ++   +Q + I  L    S+  IE +SL+ + + L+++L+GK+   +SE+ +VR+E   +I  L++ER +Q  L  KI   +++I+ +  + RE    + +EM +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S  + F+
Sbjct:    1 MEDFRRSYLRL-----FDTQESVLAQLHDTRTVTGSSR--LDLSGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHNVDRQSTLRESKSRTQ--------VLSKEIQLLK-----DEKSRQVRISG------IIHLHCLQEALNEQKSSVNSLTAKLQMTEAALALSE--QKNHDLA---DLLTRVKMEKN---ELRERQSREIKKEHEHLKEVNSLSEKNLQLRSKLEETERRCKTQQDQIFELKQELTNTTAELKLRLAQTEERLEMEKRRAKQALEDMDGLRQKEVKML----DCTSFIYKKMLVFFLKFIQGI--ELSRVKASLVTERAQAEEELGKVRSQVRLEEQQHLTSLEEKLRAVRQSRDESQNHCTQQKQTIAELHAKVSQQSIETDSLRRRIDELQQDLAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFS 635

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Match: lrrc45 (leucine rich repeat containing 45 [Source:ZFIN;Acc:ZDB-GENE-121214-317])

HSP 1 Score: 229.18 bits (583), Expect = 1.577e-65
Identity = 195/680 (28.68%), Postives = 334/680 (49.12%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKS--FSKIIQLEKLLDERKQKCQ-----HLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIK-NDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+F+  +L LCK+  +   + ++  +      T S    L LS +S++ + C VL+   ++DT F EI   DCMLS + ++++L GL  N     L LKGNN++  G E+L +L+ RN  +  L LEWN +G+   GF  FC GL ++ +L  LDLRNNQI       L  AL++N+NL+ LD+R+N++G+ GG+ +L   ++NRTL+K+ + GNNIP D ++ IE   N N                                     +D Q S LR S  ++   SK IQL K  DE+ ++ +     HL+    + E+K        KE ++  +K+L+ R  LE +   +   ++D   E+++      + L+ R+ Q +                VF++ D +T    + +  +   +E+I+KL+ Q          Q ++E+++++        +  E+L K   ++R E  Q ++SL+ ++ + R   DE  +   Q     Q Q I++L  ++    I  D +        R I+ LQ+D                     L+GK+   +SE+ +VR+E   +I  L++ER +Q  L  KI   +++I+ +  + RE    + +EM +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S  + F+
Sbjct:    1 MEDFRRSYLRLCKEGGVDTQESVLAQLHDTRTVTGSSR--LDLSGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHN-------------------------------------VDRQ-STLRESKSRTQVLSKEIQLLK--DEKSRQVRISGIIHLHCENAVREAK------HLKEVNSLSEKNLQLRSKLE-ETERRCKTQQDQIFELKQELTNTTAELKLRLAQTE------------VFYFVFQV-DHLTRHQEDSERAL---QERILKLEGQRI--------QLEEELSRVKASLVTERAQAEEELGKVRSQVRLEEQQHLTSLEEKLRAVRQSRDESQNHCTQ-----QKQTIAELHAKVSQQSIETDSLR-------RRIDELQQD---------------------LAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFS 574

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Match: pth2r (parathyroid hormone 2 receptor [Source:Xenbase;Acc:XB-GENE-1018413])

HSP 1 Score: 231.491 bits (589), Expect = 3.670e-65
Identity = 195/674 (28.93%), Postives = 367/674 (54.45%), Query Frame = 1

Query:   34 IMSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE---ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKERE--YLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            I  ++ FK  ++ +C++    P + ++  ++    +T  K   L LS +S+S E C+VL    ++D TF ++   DCM+S D L+  L+G+  N     L LKGNN++ +G E+L + +   +++T L+LEWN +G    GF  FC GL  N++LQ LDLRNNQI     + L  ALQ+N+ L+ LD+R+N+IG+ GG+ I + FE N+ L K+ + GNNI  D++K IE     N E   + + N   N +     +  N +  +  Q +++++ ID+Q   +   ++ +  +  +L   L+ER      L A L L E+ L +   Q +++     + +K+++   +E+     +  ++++R E E +  ++ +   E+ L  ++K+ ELE     Q + VFELK ++T T +E K + +  EE+    K + ++          KE++ M       E   +E++ + +  +  L +E+S LK  +++   Q +E++ K++  +  E +Q  + L ++L+T+   +D+ ++Q  +Q + I  LQ  N++L +E+E LK + + +++EL+ K+   +S + KVR+E+  +I  LE++  +Q  L  KI   ++Q +   +  RE    + +E+ TL ++L+ ++ E+ R  E+E  RA  L NA+  +   S
Sbjct:   32 IYEMDEFKRLYVFMCQERGSEPQESVLSQMKEIREST--KRRQLDLSTQSISQESCQVLGILLQNDVTFTQVLLSDCMISEDGLKAFLQGMQSNSVIKHLDLKGNNLQAKGGEALGKFLRHTASLTSLTLEWNNLGTWENGFSFFCEGLALNQSLQKLDLRNNQINHKGAEELAMALQRNSTLQELDLRWNNIGLLGGRAIQSCFESNKALVKLELSGNNISSDVLKAIELCIKHNQERQFVKKGN--MNQQQILTKEVQNLKQDKNRQFINMMETIDKQREEMNSINRNAVLQAGKLRGTLEERTSVVNSLTAKLQLMEADLALSH-QKEQDLGDLLRQVKQQDSSMMEKHAKELMKAKEEFR-EHEAKRRRDLAAANEKNLHYRSKIDELERKCQTQQDLVFELKQELTNTTAELKLRAVQAEERFEAEKKRFRQFRDNSTTLHQKEVDHMAKHLEDAERVTQERVQRLEATKLGLEEELSRLKIMLANQHTQAEEELQKVRSFVQLE-EQHSAVLHDKLRTLTQSRDQAQNQVLQQNQMIGELQTKNNQLSLEIEVLKRRIDGIQQELATKEEEKLSALTKVRVEFHEQIGHLEAQLATQEGLREKISALERQQKVQSHQHREILLDKESEISTLMEKLRLKDAEILRIREEEAHRACLLQNAIHSFISSS 698

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Match: pth2r (parathyroid hormone 2 receptor [Source:Xenbase;Acc:XB-GENE-1018413])

HSP 1 Score: 205.297 bits (521), Expect = 2.301e-56
Identity = 191/673 (28.38%), Postives = 349/673 (51.86%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQL---ILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE---ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDAS-FQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ FK  ++ +C++    P + ++  ++    +T  K   L LS +S+S E C+VL    ++D TF ++   DCM+S D   +    L+G+  N     L LKGNN++ +G E+L + +   +++T L+LEWN +G    GF  FC GL  N++LQ LDLRNNQI     + L  ALQ+N+ L+ LD+R+N+IG+ GG+ I + FE N+ L K+ + GNNI  D++K IE     N E   + + N   N +     +  N +  +  Q +++++ ID+Q   +   ++     ++Q+ K        C  LN +L +    + +  +Q K+ D+S  +K  KE           L K K+ RI+  +R  + Q +L                        VFELK ++T T +E K + +  EE+    K + ++          KE++ M       E   +E++ + +  +  L +E+S LK  +++   Q +E++ K++  +  E +Q  + L ++L+T+   +D+ ++Q  +Q + I  LQ  N++L +E+E LK + + +++EL+ K+   +S + KVR+E+  +I  LE++  +Q  L  KI   ++Q +   +  RE    + +E+ TL ++L+ ++ E+ R  E+E  RA  L NA+  +   S
Sbjct:    1 MDEFKRLYVFMCQERGSEPQESVLSQMKEIREST--KRRQLDLSTQSISQESCQVLGILLQNDVTFTQVLLSDCMISEDGKLVGLSFLQGMQSNSVIKHLDLKGNNLQAKGGEALGKFLRHTASLTSLTLEWNNLGTWENGFSFFCEGLALNQSLQKLDLRNNQINHKGAEELAMALQRNSTLQELDLRWNNIGLLGGRAIQSCFESNKALVKLELSGNNISSDVLKAIELCIKHNQERQFVKKGN--MNQQQILTKEVQNLKQDKNRQFINMMETIDKQREEMNSINR----SVVQVSK-------DC--LNCSL-VRLIDILLIPLQVKQQDSSMMEKHAKE-----------LMKAKEVRIDELERKCQTQQDL------------------------VFELKQELTNTTAELKLRAVQAEERFEAEKKRFRQFRDNSTTLHQKEVDHMAKHLEDAERVTQERVQRLEATKLGLEEELSRLKIMLANQHTQAEEELQKVRSFVQLE-EQHSAVLHDKLRTLTQSRDQAQNQVLQQNQMIGELQTKNNQLSLEIEVLKRRIDGIQQELATKEEEKLSALTKVRVEFHEQIGHLEAQLATQEGLREKISALERQQKVQSHQHREILLDKESEISTLMEKLRLKDAEILRIREEEAHRACLLQNAIHSFISSS 619

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Match: pth2r (parathyroid hormone 2 receptor [Source:Xenbase;Acc:XB-GENE-1018413])

HSP 1 Score: 197.978 bits (502), Expect = 9.745e-54
Identity = 189/687 (27.51%), Postives = 340/687 (49.49%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE---ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESK---LEMYEIQFKENDASF-QKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISS-------LKNQISS----DRI---QHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ FK  ++ +C++    P + ++  ++    +T  K   L LS +S+S E C+VL    ++D TF ++   DCM+S D L+  L+G+  N     L LKGNN++ +G E+L + +   +++T L+LEWN +G    GF  FC GL  N++LQ LDLRNNQI     + L  ALQ+N+ L+ LD+R+N+IG+ GG+ I + FE N+ L K+ + GNNI  D++K IE     N E   + + N   N +     +  N +  +  Q +++++ ID+Q   +   ++     ++Q+         + Q + A+L L+  K   L     Q K+ D+S  +K  KE           L K K+ RI+  +R  + Q +L                        VFELK ++T T +E K + +  EE+    K + ++          KE++ M       E   +E++ + +  +  L +  SS       L  Q+++    D I   QH   +H   + L   +DQ  +++ +Q + +     E++++NN+ + EIE L++              + + +++EL+ K+   +S + KVR+E+  +I  LE++  +Q  L  KI   ++Q +   +  RE    + +E+ TL ++L+ ++ E+ R  E+E  RA  L NA+  +   S
Sbjct:    1 MDEFKRLYVFMCQERGSEPQESVLSQMKEIREST--KRRQLDLSTQSISQESCQVLGILLQNDVTFTQVLLSDCMISEDGLKAFLQGMQSNSVIKHLDLKGNNLQAKGGEALGKFLRHTASLTSLTLEWNNLGTWENGFSFFCEGLALNQSLQKLDLRNNQINHKGAEELAMALQRNSTLQELDLRWNNIGLLGGRAIQSCFESNKALVKLELSGNNISSDVLKAIELCIKHNQERQFVKKGN--MNQQQILTKEVQNLKQDKNRQFINMMETIDKQREEMNSINRS----VVQV---------RLQLMEADLALSHQKEQDLGDLLRQVKQQDSSMMEKHAKE-----------LMKAKEVRIDELERKCQTQQDL------------------------VFELKQELTNTTAELKLRAVQAEERFEAEKKRFRQFRDNSTTLHQKEVDHMAKHLEDAERVTQERVQRLEATKLGLEEVRSSGGHMELFLCRQVAAALFLDYIAFQQHSAVLHDKLRTLTQSRDQAQNQVLQQNQMI----GELQTKNNQLSLEIEVLKR--------------RIDGIQQELATKEEEKLSALTKVRVEFHEQIGHLEAQLATQEGLREKISALERQQKVQSHQHREILLDKESEISTLMEKLRLKDAEILRIREEEAHRACLLQNAIHSFISSS 617

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Match: pth2r (parathyroid hormone 2 receptor [Source:Xenbase;Acc:XB-GENE-1018413])

HSP 1 Score: 197.208 bits (500), Expect = 1.139e-53
Identity = 175/604 (28.97%), Postives = 328/604 (54.30%), Query Frame = 1

Query:  253 FKDCMLSP---DCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE---ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKERE--YLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
             +DC LS    + L+  L+G+  N     L LKGNN++ +G E+L + +   +++T L+LEWN +G    GF  FC GL  N++LQ LDLRNNQI     + L  ALQ+N+ L+ LD+R+N+IG+ GG+ I + FE N+ L K+ + GNNI  D++K IE     N E   + + N   N +     +  N +  +  Q +++++ ID+Q   +   ++ +  +  +L   L+ER      L A L L E+ L +   Q +++     + +K+++   +E+     +  ++++R E E +  ++ +   E+ L  ++K+ ELE     Q + VFELK ++T T +E K + +  EE+    K + ++          KE++ M       E   +E++ + +  +  L +E+S LK  +++   Q +E++ K++  +  E+ Q  + L ++L+T+   +D+ ++Q  +Q + I  LQ  N++L +E+E LK + + +++EL+ K+   +S + KVR+E+  +I  LE++  +Q  L  KI   ++Q +   +  RE    + +E+ TL ++L+ ++ E+ R  E+E  RA  L NA+  +   S
Sbjct:    1 MQDCWLSAQHSEGLKAFLQGMQSNSVIKHLDLKGNNLQAKGGEALGKFLRHTASLTSLTLEWNNLGTWENGFSFFCEGLALNQSLQKLDLRNNQINHKGAEELAMALQRNSTLQELDLRWNNIGLLGGRAIQSCFESNKALVKLELSGNNISSDVLKAIELCIKHNQERQFVKKGN--MNQQQILTKEVQNLKQDKNRQFINMMETIDKQREEMNSINRNAVLQAGKLRGTLEERTSVVNSLTAKLQLMEADLALSH-QKEQDLGDLLRQVKQQDSSMMEKHAKELMKAKEEFR-EHEAKRRRDLAAANEKNLHYRSKIDELERKCQTQQDLVFELKQELTNTTAELKLRAVQAEERFEAEKKRFRQFRDNSTTLHQKEVDHMAKHLEDAERVTQERVQRLEATKLGLEEELSRLKIMLANQHTQAEEELQKVRSFVQLEEQQHSAVLHDKLRTLTQSRDQAQNQVLQQNQMIGELQTKNNQLSLEIEVLKRRIDGIQQELATKEEEKLSALTKVRVEFHEQIGHLEAQLATQEGLREKISALERQQKVQSHQHREILLDKESEISTLMEKLRLKDAEILRIREEEAHRACLLQNAIHSFISSS 600

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Match: hcn4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4 [Source:Xenbase;Acc:XB-GENE-940130])

HSP 1 Score: 70.4774 bits (171), Expect = 4.132e-12
Identity = 41/110 (37.27%), Postives = 59/110 (53.64%), Query Frame = 1

Query:  337 LKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTL 666
            L  NN+   G ++LA  ++ N T+ +LSL  N VG    G    CN L+ N+TLQ L L +N++       L++AL  N +L+ L +  N IG  GGK +L     N TL
Sbjct:  312 LSNNNVGAHGAQALAHALTNNWTLRNLSLRLNHVG--NEGGQALCNALLPNQTLQELHLGSNELSEPTASALSQALTHNGSLRRLSLACNRIGPDGGKQLLEGMSDNETL 419

HSP 2 Score: 55.0694 bits (131), Expect = 3.343e-7
Identity = 39/142 (27.46%), Postives = 60/142 (42.25%), Query Frame = 1

Query:  376 LARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR 801
            L R +  +  +  L L  NQV   G    +    L+    L+VLDL NN +G    Q L  AL  N  L+ L +R N +G  GG+ + N    N+TL ++ +  N +       +      NG +   +   N      GK+
Sbjct:  270 LVRSLLNHPALVHLDLSHNQVSDRGA---RAIAKLLKESALRVLDLSNNNVGAHGAQALAHALTNNWTLRNLSLRLNHVGNEGGQALCNALLPNQTLQELHLGSNELSEPTASALSQALTHNGSLRRLSLACNRIGPDGGKQ 408

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Match: Lrrc45 (leucine rich repeat containing 45 [Source:MGI Symbol;Acc:MGI:2387183])

HSP 1 Score: 266.544 bits (680), Expect = 1.689e-78
Identity = 191/667 (28.64%), Postives = 364/667 (54.57%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T  +E+   DCMLS +   L+ +GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  L+ LDLRNNQI     + L  AL+ NT L+ LD+R+N+IG+ GG+ ++N    NRTL K+ + GNNIP DI++ +E   + N +   A   + +R+    K   + +  +  Q LDL++ ID+Q   +    + S  ++ QL++ L+ER+     L A L + E+ L + E + ++         +ER+ L +++  +   E+    + E + L++ S   E+ L L+++V ELE     Q   +F  K ++T T++E K + +  EE++   K + K+ M ++ +   KE++ M      +E   +E++ + + +R  L +E+S +K  + S+R Q +E++ K + +   E+  +++ L+E+++ +   +DE +    +Q + +   Q   S+L +++E  + + E L++EL  K    ++E+ +VR+E   ++ +++++  +Q  L  K+   ++Q++ + +  RE    R +E  +L+++L+ +E E++R  ++E  RAS L NAV+ Y Q S
Sbjct:    1 MEEFRRSYNRLCEESGAEPQEAVLQQLHQLPKGG------LDLTTQSLTVETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRTLWKLDLAGNNIPGDILRAVEQAMDHNQDRLTAFRENQARTKILSKEVQHLQEEKSKQFLDLMETIDKQREEMARDSRASAVRVGQLQEALNERQSIINALKAKLQMTEAALALSEQKVRDLGELLVAGDQERQSLSQRHEKERKLERQEAADRESKLLRDLSAASEKNLLLRSQVDELERKARSQQEQLFLTKQELTNTSAELKIRAIQAEERLDVEKRRAKQNMEDLEKLHSKEVDHMTRHLEESERAMQERVQRLEALRLSLEEELSRMKAAVLSERGQAEEELIKARNQARLEEQHRLAHLEEKIRLLAQARDEAQGTCVQQKQMVAESQARVSQLNLQMEGQQRRLEELQQELINKDQEKVAEVARVRVELQEQMGRMQADLVAQEALREKVAALERQMKVIGSEHREALLDRESENASLREKLRLKEAEISRIRDEEAQRASFLQNAVLAYVQGS 661

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Match: Lrrc45 (leucine rich repeat containing 45 [Source:MGI Symbol;Acc:MGI:2387183])

HSP 1 Score: 202.601 bits (514), Expect = 2.602e-57
Identity = 129/418 (30.86%), Postives = 222/418 (53.11%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYE 1293
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T  +E+   DCMLS +   L+ +GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  L+ LDLRNNQI     + L  AL+ NT L+ LD+R+N+IG+ GG+ ++N    NRTL K+ + GNNIP DI++ +E   + N +   A   + +R+    K   + +  +  Q LDL++ ID+Q   +    + S  ++ QL++ L+ER+     L A L + E+ L + E + ++         +ER+ L +++  +   E+    + E + L++ S   E+ L L+++V ELE     Q   +F  K ++T T++E K + +  E
Sbjct:    1 MEEFRRSYNRLCEESGAEPQEAVLQQLHQLPKGG------LDLTTQSLTVETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRTLWKLDLAGNNIPGDILRAVEQAMDHNQDRLTAFRENQARTKILSKEVQHLQEEKSKQFLDLMETIDKQREEMARDSRASAVRVGQLQEALNERQSIINALKAKLQMTEAALALSEQKVRDLGELLVAGDQERQSLSQRHEKERKLERQEAADRESKLLRDLSAASEKNLLLRSQVDELERKARSQQEQLFLTKQELTNTSAELKIRAIQAE 412

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Match: Lrrc45 (leucine rich repeat containing 45 [Source:MGI Symbol;Acc:MGI:2387183])

HSP 1 Score: 108.612 bits (270), Expect = 5.794e-27
Identity = 56/162 (34.57%), Postives = 87/162 (53.70%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQI 528
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T  +E+   DCMLS +   L+ +GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  L+ LDLRNNQI
Sbjct:    1 MEEFRRSYNRLCEESGAEPQEAVLQQLHQLPKGG------LDLTTQSLTVETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQI 156

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Match: Nlrc3 (NLR family, CARD domain containing 3 [Source:MGI Symbol;Acc:MGI:2444070])

HSP 1 Score: 68.1662 bits (165), Expect = 1.309e-11
Identity = 51/180 (28.33%), Postives = 85/180 (47.22%), Query Frame = 1

Query:  163 LTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWN--QVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            L L   S+S     VL      + T   ++ ++  +SP+  Q + + L  N     L L  N + ++G +++A  +  N ++T L L+WN  Q G +          L  N+TL  LDL+ N IG +    +  AL+ NT L  L ++  SIG  G + +      NRTL  + + GN++
Sbjct:  143 LDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAA----RALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 318

HSP 2 Score: 61.2326 bits (147), Expect = 2.547e-9
Identity = 46/157 (29.30%), Postives = 70/157 (44.59%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSI 612
            +N  L  L L E S+S E  + L++    + T + +     +L     Q I   + +N     L L+ N I+     +L + +  N T+T L L+ N +G  G         L  N TL  L L+   IG    Q L EAL  N  L++LD+R N +
Sbjct:  164 SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGA--SSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 318

HSP 3 Score: 59.3066 bits (142), Expect = 9.789e-9
Identity = 46/170 (27.06%), Postives = 81/170 (47.65%), Query Frame = 1

Query:  166 TLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            +L+E  +  +  K L+     + +   +  +   + P   + + + L  N     L L+ N IK+ G   +A  +  N TI+ L L+ N +G+   G  Q  + L  N++L+ L   +N IG      L EAL+ N  L+ LD++ NSI   G  +++     N+TLS +
Sbjct:    4 SLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGL--IGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSL 171

HSP 4 Score: 54.6842 bits (130), Expect = 3.186e-7
Identity = 50/204 (24.51%), Postives = 82/204 (40.20%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVG--------------------------ISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
             N  L  L L   S+     K L++  + + T   +S +  ++  D +  + E L  N     L L+ N I   G + +A  + +N ++  L    N +G                          IS  G       L +N+TL  L+LR N I  +  Q LT+AL +N  LK LD+  N +   G + I     +N +L+ +
Sbjct:   24 VNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHL 227

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Match: Nlrc3 (NLR family, CARD domain containing 3 [Source:MGI Symbol;Acc:MGI:2444070])

HSP 1 Score: 68.5514 bits (166), Expect = 2.873e-11
Identity = 50/178 (28.09%), Postives = 83/178 (46.63%), Query Frame = 1

Query:  163 LTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            L L   S+S     VL      + T   ++ ++  +SP+  Q + + L  N     L L  N + ++G +++A  +  N ++T L L+WN   I           L  N+TL  LDL+ N IG +    +  AL+ NT L  L ++  SIG  G + +      NRTL  + + GN++
Sbjct:  848 LDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNF--IQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 1023

HSP 2 Score: 62.3882 bits (150), Expect = 1.962e-9
Identity = 55/232 (23.71%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  103 DFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
            D +++ + S     + ++  ++L+E  +  +  K L+     + +   +  +   + P   + + + L  N     L L+ N IK+ G   +A  +  N TI+ L L+ N +G+   G  Q  + L  N++L+ L   +N IG      L EAL+ N  L+ LD++ NSI   G  +++     N+TLS + +  N+I  +  + +     RN  +   +  +N   DR  +
Sbjct:  688 DPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGL--IGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQ 917

HSP 3 Score: 59.6918 bits (143), Expect = 1.493e-8
Identity = 46/157 (29.30%), Postives = 70/157 (44.59%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSI 612
            +N  L  L L E S+S E  + L++    + T + +     +L     Q I   + +N     L L+ N I+     +L + +  N T+T L L+ N +G  G         L  N TL  L L+   IG    Q L EAL  N  L++LD+R N +
Sbjct:  869 SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGA--SSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 1023

HSP 4 Score: 53.9138 bits (128), Expect = 9.384e-7
Identity = 50/204 (24.51%), Postives = 82/204 (40.20%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVG--------------------------ISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
             N  L  L L   S+     K L++  + + T   +S +  ++  D +  + E L  N     L L+ N I   G + +A  + +N ++  L    N +G                          IS  G       L +N+TL  L+LR N I  +  Q LT+AL +N  LK LD+  N +   G + I     +N +L+ +
Sbjct:  729 VNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHL 932

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Match: sp|Q5ZI11|LRC45_CHICK (Leucine-rich repeat-containing protein 45 OS=Gallus gallus OX=9031 GN=LRRC45 PE=2 SV=1)

HSP 1 Score: 277.715 bits (709), Expect = 1.025e-81
Identity = 200/677 (29.54%), Postives = 370/677 (54.65%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE----ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFAL 2061
            +E F+  +  LC      P + +++ ++    A       L L+E+S+S E C  L         F E++  DC LS D ++L+L GL  N     L LKGNN++  G E+L +L+ +N +I  L LEWN +G+   GF  FC GL  N  LQ LDLRNNQI       L  AL++N +L+ LD+R+N+IG+ GG+ +LN  + N+TL K+ + GNN+P DI+K +E   + N +    +SE   R++  S    +  N ++ +  Q LDL+D ID+Q   +  S + S  ++ QL++ L+E+      L A L + E+ L + E +          + +E+  +  ++  +L ++K    + E +  ++ S   E+ L L+N+V ELE     Q + +F+LK  +T T +E K + +  EE++   K + K+ + ++   + KE++ +      +E   ++++ + + IR  L +E+S +K    ++R   +E++ K++ +   E+ Q++  L+E+L+ M   +DE ++   +Q + +   Q   ++L +  + L+ + E L+++L+ K+   ++E+ KV++E   +I  L++ER +Q  L  KI   ++Q++ + ++ RE    +  E+  L ++L+ +E +++R  E+E  RAS L NA+M Y Q S   + +L
Sbjct:    1 MEEFRRAYAKLCA----APQEAVLRRLRERGEAPGR--ARLDLAEQSLSLETCGALGRLLPGAAHFAEVALGDCGLSEDGVKLLLHGLCSNSTVKSLDLKGNNLRTTGAEALGKLLRQNKSIRSLILEWNSLGVWEEGFSFFCQGLGANNFLQRLDLRNNQINHHGAGELAMALKRNASLQELDLRWNNIGLLGGRALLNCLQSNKTLKKLELAGNNVPSDILKAVEQAMDHNRDRQTILSETQNRTSVLSK---EILNLKDEKTKQFLDLMDTIDKQREEIARSGRISAGRVSQLQEALNEQHSIMNSLKAKLQMTEAALALSEQKVHNLGELLSATKQEQASMAERHFAELQQQKQEGADREGKLFRDLSASNEKNLFLRNQVDELEKKCKVQQDQIFQLKQDLTNTTAELKLRAVQAEERLEMEKRRFKQSLEDMESLRLKEVDHLTQHMEASERSMQDRVQRLEAIRIALEEELSQVKAAALTERGHAEEELIKVRNQARLEEQQRVEHLEEKLRLMTEARDEAQNCCLKQKQMVGEAQVKANQLNLHADGLRRRIEELQQDLNSKEQEKVTEVNKVKVELQEQIGHLQAERTAQEGLREKIAALERQLKVLSSNHREALLDKEGEISMLMEKLRMKEADISRMKEEEAQRASILQNAIMAYVQGSSLGTHSL 668

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Match: sp|Q8CIM1|LRC45_MOUSE (Leucine-rich repeat-containing protein 45 OS=Mus musculus OX=10090 GN=Lrrc45 PE=2 SV=2)

HSP 1 Score: 266.544 bits (680), Expect = 1.181e-77
Identity = 191/667 (28.64%), Postives = 364/667 (54.57%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T  +E+   DCMLS +   L+ +GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  L+ LDLRNNQI     + L  AL+ NT L+ LD+R+N+IG+ GG+ ++N    NRTL K+ + GNNIP DI++ +E   + N +   A   + +R+    K   + +  +  Q LDL++ ID+Q   +    + S  ++ QL++ L+ER+     L A L + E+ L + E + ++         +ER+ L +++  +   E+    + E + L++ S   E+ L L+++V ELE     Q   +F  K ++T T++E K + +  EE++   K + K+ M ++ +   KE++ M      +E   +E++ + + +R  L +E+S +K  + S+R Q +E++ K + +   E+  +++ L+E+++ +   +DE +    +Q + +   Q   S+L +++E  + + E L++EL  K    ++E+ +VR+E   ++ +++++  +Q  L  K+   ++Q++ + +  RE    R +E  +L+++L+ +E E++R  ++E  RAS L NAV+ Y Q S
Sbjct:    1 MEEFRRSYNRLCEESGAEPQEAVLQQLHQLPKGG------LDLTTQSLTVETCRALGKLLHKETLLKELVLSDCMLSEEGSTLLFQGLCANTSVQHLDLKGNNLRATGAEALGKLLRQNKSIQSLTLEWNNLGTWEDAFATFCGGLAANSALRQLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNIGLLGGRALVNCLPSNRTLWKLDLAGNNIPGDILRAVEQAMDHNQDRLTAFRENQARTKILSKEVQHLQEEKSKQFLDLMETIDKQREEMARDSRASAVRVGQLQEALNERQSIINALKAKLQMTEAALALSEQKVRDLGELLVAGDQERQSLSQRHEKERKLERQEAADRESKLLRDLSAASEKNLLLRSQVDELERKARSQQEQLFLTKQELTNTSAELKIRAIQAEERLDVEKRRAKQNMEDLEKLHSKEVDHMTRHLEESERAMQERVQRLEALRLSLEEELSRMKAAVLSERGQAEEELIKARNQARLEEQHRLAHLEEKIRLLAQARDEAQGTCVQQKQMVAESQARVSQLNLQMEGQQRRLEELQQELINKDQEKVAEVARVRVELQEQMGRMQADLVAQEALREKVAALERQMKVIGSEHREALLDRESENASLREKLRLKEAEISRIRDEEAQRASFLQNAVLAYVQGS 661

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Match: sp|Q96CN5|LRC45_HUMAN (Leucine-rich repeat-containing protein 45 OS=Homo sapiens OX=9606 GN=LRRC45 PE=1 SV=1)

HSP 1 Score: 265.388 bits (677), Expect = 3.402e-77
Identity = 199/673 (29.57%), Postives = 361/673 (53.64%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY---ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKD----KEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E F+  +  LC++    P + ++Q +             L L+ +S++ E C+ L +    +T   E+   DCMLS +   L+L GL  N     L LKGNN++  G E+L +L+ +N +I  L+LEWN +G     F  FC GL  N  LQ LDLRNNQI     + L  AL+ NT L+ LD+R+N++G+ GG+ ++N    NRTL ++ + GNNIP D+++ +E     + +     + + +R+    K   +   E S+  Q LDL++ ID+Q   +  S + S +++ QL++ L+ER      L A L + E+ L + E + ++       + +E+  L ++   +L  E+    E E + L++ S   E+ L LQN+V ELE     Q   +F+ + ++T  ++E K + +  EE++    D  K+   + +E  +    KE+  M      +E+  +E++ + +  R  L +E+S +K    S+R Q +E++ K K +   E+ Q+++ L+++L+ +   +DE +    +Q + +   Q   S+L +++E L+ + E L++ELS K    ++E+ +VR+E   +  +L++E  +Q  L  K    ++Q++ M +  RE    R +E  +L+++L+ +E E+ R  ++E  RAS L NAV+ Y Q S
Sbjct:    1 MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGR------LDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSK--QFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERL----DMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQAS 661

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Match: sp|Q7RTR2|NLRC3_HUMAN (NLR family CARD domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NLRC3 PE=1 SV=2)

HSP 1 Score: 76.2554 bits (186), Expect = 6.698e-13
Identity = 64/245 (26.12%), Postives = 98/245 (40.00%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQV--------------------------GISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
             N  L  L L   S+S      L      + T   +S ++  +SP+  Q I   L  N     L L  N + +QG  ++A  +  N T+T L L+WN +                           I   G       L  N  L  L L+   IG    Q+L EAL  N  L++LD+R N+IGV+G K + N  + N +L ++ +  N++ MD    I    + N  +   N + N   D   +
Sbjct:  804 VNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGAR 1048

HSP 2 Score: 68.9366 bits (167), Expect = 1.364e-10
Identity = 53/178 (29.78%), Postives = 90/178 (50.56%), Query Frame = 1

Query:  253 FKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            F+D ++  + L  +L G   +C   K+ L  N I N+G ++LAR +  N ++T L L  N +G  G       + L  N+TL  L L+ N +  D  + + EAL  N  L +L ++ NSIG  G + + +  ++NR+L +++   N+I     K +      N  +   + +SNS SD
Sbjct:  649 FQDPVM--ELLGSVLSG--KDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGA--KALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISD 820

HSP 3 Score: 68.9366 bits (167), Expect = 1.376e-10
Identity = 49/208 (23.56%), Postives = 102/208 (49.04%), Query Frame = 1

Query:  103 DFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIEN 726
            D +++ + S     + ++  ++L+E  +S +  K L+     + +   +  +   + P   + + + L  N     L L+GN +++ G  S+A  ++ N T++ L L+ N +G  G    +  + L  N++L+ L   +N IG    + L EAL+ N  L+ LD++ NSI  +G   ++     N+TL  + +  N+I  +  + I +
Sbjct:  651 DPVMELLGSVLSGKDCRIQKISLAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGA--QRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAH 856

HSP 4 Score: 60.4622 bits (145), Expect = 5.695e-8
Identity = 47/177 (26.55%), Postives = 78/177 (44.07%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            N  L  L+L   ++  +  + ++E    + T   +  +   + P   Q + + L  N    +L    N+I + G ++LA  +  N  +  L L+ N   IS  G       L  N+TL  L LR N I  +  Q +  AL  N+ LK LD+  N +   G + I     +NRTL+ +
Sbjct:  721 NRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNS--ISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSL 895

HSP 5 Score: 55.4546 bits (132), Expect = 2.133e-6
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 1

Query:  322 CIKLCLKGNNIKNQGCESLARLIS-RNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI-PMDIIKNIENLANRNGEISEANERSNSRSDRNGK--RNNYENSRKLQTLDL 843
            C KL L  N  ++   E L  ++S ++  I  +SL  NQ  IS  G       L+ N++L  LDLR N IG    + L +AL+ N  L  L ++ N++   G + +      NRTLS + +  N+I PM   +  + L  +N  + E    SNS  D   K      + ++ L++LDL
Sbjct:  639 CRKLRLDTNQFQDPVMELLGSVLSGKDCRIQKISLAENQ--ISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADAL-KQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDL 813

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Match: sp|Q5DU56|NLRC3_MOUSE (Protein NLRC3 OS=Mus musculus OX=10090 GN=Nlrc3 PE=1 SV=2)

HSP 1 Score: 68.1662 bits (165), Expect = 2.091e-10
Identity = 50/178 (28.09%), Postives = 83/178 (46.63%), Query Frame = 1

Query:  163 LTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            L L   S+S     VL      + T   ++ ++  +SP+  Q + + L  N     L L  N + ++G +++A  +  N ++T L L+WN   I           L  N+TL  LDL+ N IG +    +  AL+ NT L  L ++  SIG  G + +      NRTL  + + GN++
Sbjct:  810 LDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNF--IQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 985

HSP 2 Score: 62.3882 bits (150), Expect = 1.324e-8
Identity = 55/232 (23.71%), Postives = 107/232 (46.12%), Query Frame = 1

Query:  103 DFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
            D +++ + S     + ++  ++L+E  +  +  K L+     + +   +  +   + P   + + + L  N     L L+ N IK+ G   +A  +  N TI+ L L+ N +G+ G    Q  + L  N++L+ L   +N IG      L EAL+ N  L+ LD++ NSI   G  +++     N+TLS + +  N+I  +  + +     RN  +   +  +N   DR  +
Sbjct:  650 DPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGA--QQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQ 879

HSP 3 Score: 59.6918 bits (143), Expect = 9.910e-8
Identity = 46/157 (29.30%), Postives = 70/157 (44.59%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSI 612
            +N  L  L L E S+S E  + L++    + T + +     +L     Q I   + +N     L L+ N I+     +L + +  N T+T L L+ N +G  G         L  N TL  L L+   IG    Q L EAL  N  L++LD+R N +
Sbjct:  831 SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGA--SSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 985

HSP 4 Score: 53.5286 bits (127), Expect = 6.678e-6
Identity = 50/204 (24.51%), Postives = 82/204 (40.20%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVG--------------------------ISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
             N  L  L L   S+     K L++  + + T   +S +  ++  D +  + E L  N     L L+ N I   G + +A  + +N ++  L    N +G                          IS  G       L +N+TL  L+LR N I  +  Q LT+AL +N  LK LD+  N +   G + I     +N +L+ +
Sbjct:  691 VNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHL 894

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BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Match: A0A3S1AUP5 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_019570 PE=4 SV=1)

HSP 1 Score: 341.273 bits (874), Expect = 3.394e-103
Identity = 231/664 (34.79%), Postives = 393/664 (59.19%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYC 2031
            +E+F++ ++ LCK   + P + +++ ++S    +  K   L LS  S+S + C VL +    D TF EI F DCML+ D ++ + +GL+ N  C KL LKGNNI+    E+L +++ +N T+  + LEWN +G+  + F  FC+G+ ++ +L  LDLRNNQI  D+   L  AL++N +LK LD+R+N+ G+ GG+ +L + + N+TLS++ I GNNIP D+ K+IE     N +     E +  R+    K   N E  RKLQ  DLL  +DEQ + LR S + S  +I  L+  LDERK     L A L++AE++L + E +  + +++  +   E + +   +   + +EK+ R   + +FLKE S LQ++  QLQ KV +L+    QQ   V++L++ +T   SE   K   +EE+I + K ++K+ M +  + K KEM +++ E    E   RE++ K ++ R ++ +EIS LK    +D++ ++E +  +K +L +E++Q+  +L+E+++ +Q  KDE++S  N+Q   +  LQ  NS L++ELE+LK + + L +ELS K +   +E+EKV++E    + KLE ER +Q +L  K+   D Q+ E     R+    ++ E+ TL+++LK +++EL R  E+E  R   L +A++ Y 
Sbjct:    2 MEDFRHIYIRLCKDHHVDPQECVLEKLKSLEKKSTGK-AILDLSTNSLSPKTCAVLGKALVADRTFIEIKFSDCMLAEDAVKGLAQGLAFNTFCRKLDLKGNNIRGASTEALGKMLRQNKTLVSMCLEWNGMGMLDSSFAVFCDGVGSSTSLMALDLRNNQISHDSVIELAAALKRNVHLKALDLRWNNCGLLGGRALLEMLQSNKTLSRLEIAGNNIPSDVSKSIETAVQNNADRQAIVEENLKRTQTMAKHIRNVEQDRKLQLNDLLTTLDEQETLLRKSKRASTEQIGNLQFALDERKGAFNSLAAKLSMAETELALSEQKVSDFNSTVNRLKAEMQEMAANHVNDIRREKEERANEDLKFLKEISELQDKNTQLQTKVEDLDRKCRQQQEQVYDLREHLTHAQSEVTLKGSQFEERITQEKARHKEAMRDQDQYKQKEMARLKQEGEDMERILRERISKLEQHRLDMEEEISRLKATNVADKLNNEEQVSSLKHRLKSEEEQRHVQLEEKIRVLQTSKDELQSHCNQQTASLTQLQHRNSNLQLELENLKRQMQELNQELSQKNSQTYAEVEKVKVELNKALSKLEQERSTQSELRDKLASVDSQMSEQLLKHRKIVEEKDKEIVTLEEKLKGRDLELVRMREEEAQRVQVLQSAILNYV 664

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Match: A0A1S3IM07 (leucine-rich repeat-containing protein 45 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106165548 PE=4 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 1.772e-101
Identity = 227/680 (33.38%), Postives = 401/680 (58.97%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYEN-----SRKLQTL---------DLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ FK+ +L LC++  + P D +++ ++    +       L LS  S+S + C VL +    D TF EI   DCML+ D ++ +  GL++N  C +L LKGNN++  G E+LAR++  N ++T L LEWN +G+    F  FC  L  N TL+ LDLRNNQI  D  Q L  AL++NT L+ +D+R+N++G+ GG+ +L    +N+T+ K+ + GNNIP D++++I+     N              DR    N+Y       S +L+TL         +L+ +IDEQ   +R + + S  KI QL+  L+ERK   + L A L++ ES+L + + +  + +    +  +++  L  ++   L +E++ R  +E R L+E S   +R +QL+ K  EL     QQ + +++LK+++T   ++ K K   YEE++   K +NK+ + EV   K +E+ K++ +++  E++ RE++ K +  R EL +E+S LK+Q ++DRI+ +E++  +KQK+ ++++Q+  +L+++++ +Q  KDE++S +N Q   I  LQ  NS +++ELE+ K + +    ELSGK   MM+E+ KV+LE   ++ +LE+ERQ+Q +L  +IE   +QI E     RE  + +  E+++L+++++ ++ EL R  E++  R+S L +A+M Y   S
Sbjct:    1 MDEFKSAYLRLCREYNVEPHDALMKQLKIIPTSPRKGKQSLKLSSVSLSPKTCTVLGKVLATDHTFTEIKLADCMLNEDAVKSLAYGLAENVVCKRLDLKGNNVRGTGTEALARMLRHNKSLTSLCLEWNAMGMIDNSFGTFCEALAVNTTLKELDLRNNQISHDGAQELASALKRNTTLQAIDLRWNNVGIIGGRALLEALRRNKTIYKLSLAGNNIPTDVLQSIDTALGHN-------------EDRQLMSNDYYQRTHMLSSELRTLKEEKMMQMSELMGKIDEQEDFMRKTTRSSSHKIGQLQSALEERKAAFESLKAKLSMVESELALEQQKSHDLEGLVARMKQDQSELSSRHQSDLRQEREDRASVESRLLRELSEANDRNVQLEAKEDELSRKCKQQQDQIYDLKEQLTHAQADIKLKGAQYEEKLNNEKQKNKEILQEVESLKTREIAKLQQDFDDTEKQLRERINKLERQRLELEEEVSKLKSQAAADRIKAEEELATVKQKIRSDEEQRQKQLEDRMRLLQQSKDELQSHSNHQKALILELQGKNSSMELELETHKRRIDAQNTELSGKNNEMMAEVGKVKLEVKQKMAQLETERQAQNELKEEIERLKRQISEQTGKHRELIHDKEREIESLQEKVREKDKELIRMREEDAQRSSMLQSAIMTYVARS 667

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Match: A0A1S3INX5 (leucine-rich repeat-containing protein 45 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106165548 PE=4 SV=1)

HSP 1 Score: 331.257 bits (848), Expect = 1.842e-99
Identity = 224/680 (32.94%), Postives = 397/680 (58.38%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYEN-----SRKLQTL---------DLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ FK+ +L LC++  + P D +++ ++    +       L LS  S+S + C VL +    D TF EI   DCML+ D ++ +  GL++N  C +L LKGNN++  G E+LAR++  N ++T L LEWN +G+    F  FC  L  N TL+ LDLRNNQI  D  Q L  AL++NT L+ +D+R+N++G+ GG+ +L    +N+T+ K+ + GNNIP D++++I+     N              DR    N+Y       S +L+TL         +L+ +IDEQ   +R + + S  KI QL+  L+ERK   + L A L++ ES+L + + +  + +    +  +++  L  ++   L +E++ R  +E R L+E S   +R +QL+ K  EL     QQ + +++LK+++T   ++ K K   YEE+    K +NK+ + E+   K +E+ K++ +++  E++ RE++ K +  R EL +E+S LK+Q ++DRI+ +E++  +K K+ ++++Q+  +L+++++ +Q  KDE++S +N Q   I  LQ  NS + +ELE+ K + +    ELSGK   MM+E+ KV+LE   ++ +LE+ERQ+Q +L  +I    +QI E     RE  + +  E+++L+++++ ++ EL R  E++  R+S L +A+M Y   S
Sbjct:    1 MDEFKSAYLRLCREYNVEPHDALMKQLKIIPTSPRKGKQSLKLSSVSLSPKTCTVLGKVLATDHTFTEIKLADCMLNEDAVKSLAYGLAENVVCKRLDLKGNNVRGTGTEALARMLRHNKSLTSLCLEWNAMGMIDNSFGTFCEALAVNTTLKELDLRNNQISHDGAQELASALKRNTTLQAIDLRWNNVGIIGGRALLEALRRNKTIYKLSLAGNNIPTDVLQSIDTALGHN-------------EDRQLMSNDYYQRTHMLSSELRTLKEEKMMQMSELMGKIDEQEDFMRKTTRSSSHKIGQLQSALEERKAAFESLKAKLSMVESELALEQQKSHDLEGLVARMKQDQSELSSRHQSDLRQEREDRASVESRLLRELSEANDRNVQLEAKEDELSRKCKQQQDQIYDLKEQLTHAQADIKLKGAQYEEKFNNEKQKNKEILQEMESLKTREIAKLQQDFDDTEKQLRERINKLERQRLELEEEVSKLKSQAAADRIKAEEELATVKHKIRSDEEQRQKQLEDRMRILQQSKDELQSHSNHQQALISELQGKNSSMVLELETHKRRIDAQNTELSGKNNEMMAEVGKVKLEVKQKMAQLETERQAQNELKEEIGRLKRQISEQTGKHRELIHDKEREIESLQEKVREKDKELIRMREEDAQRSSMLQSAIMTYVARS 667

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Match: A0A1S3IMD1 (leucine-rich repeat-containing protein 45 isoform X3 OS=Lingula unguis OX=7574 GN=LOC106165548 PE=4 SV=1)

HSP 1 Score: 329.331 bits (843), Expect = 9.118e-99
Identity = 219/680 (32.21%), Postives = 398/680 (58.53%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNY--------------ENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ FK+ +L LC++  + P D +++ ++    +       L LS +S+S + C +L +    D TF EI+  +CML+   ++ +  G+++N  C +L LKGNNI+  G E+LAR++  N ++T L LE N +G+    F  FC  L  N TL+ LDLR+NQI  +  Q L  AL++NT L+ +DMR N++G  GG+ +L    +N+T+ K+ + GNNIP D++++I+     N              DR    N+Y              +  +K+Q  +L+D+IDEQ   +R + + +  KI QL+  LDERK   + L A L++ ES+L + + +  + +    +   ++  L  ++   L +E++ R  +E R L+E S + +R +QL+    EL     QQ + +++LK+++T   ++ + K   YEE++   K +NK+ + EV   K +E+ K++ +++  E++ RE++ K +  R EL +E+S LK+Q ++DRI+ +E++  +KQK+ ++++Q+  +L+++++ +Q  KDE++S +N Q   I  LQ  NS +++ELE+ K + +    ELSGK   MM+E+ KV+LE   ++ +LE+ERQ+Q +L  +IE   +QI E     RE  + +  E+++L+++++ ++ EL R  E++  R+S L +A+M Y   S
Sbjct:    1 MDEFKSAYLCLCREYNVEPHDALMKQLKIIPTSPRKGKQSLQLSRESLSPKTCTILGKVLATDHTFSEINLSNCMLNEYAVKSLAYGMAENVVCKRLDLKGNNIRETGTEALARMLRHNKSLTSLCLEQNDMGMIENSFGTFCEALAANTTLKELDLRSNQISHNGAQELASALKRNTTLQAIDMRSNNVGFIGGRALLEALRRNKTIYKLSLAGNNIPTDVLQSIDTALGHN-------------EDRQLMCNDYYQRTHMLSCELRTLKKEKKMQMSELMDKIDEQEDFMRKTTRSTSHKIGQLQSALDERKAAFKSLKAKLSMVESELALEQQKSHDLEGLVARMKTDQSELSIRHQSDLRQEREDRTSVESRLLRELSEVNDRNVQLEATEDELSRKGKQQQDQIYDLKEQLTHAQADIRLKGAQYEEKLNNEKQKNKEILQEVESLKTREIAKLQQDFDDTEKQLRERINKLERQRLELEEEVSKLKSQAAADRIKAEEELATVKQKIRSDEEQRQKQLEDRMRLLQQSKDELQSHSNHQKALILELQGKNSSMELELETHKRRIDAQNTELSGKNNEMMAEVGKVKLEVKQKMAQLETERQAQNELKEEIERLKRQISEQTGKHRELIHDKEREIESLQEKVREKDKELIRMREEDAQRSSMLQSAIMTYVARS 667

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Match: A0A2T7PVH9 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_00026 PE=4 SV=1)

HSP 1 Score: 329.331 bits (843), Expect = 9.712e-99
Identity = 225/671 (33.53%), Postives = 388/671 (57.82%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGE----ISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIE-QKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            ++ F+  ++ LCK+    P D +++ ++S           L LS  S+S + C VL +    D  F E+ F DCMLS D ++ + +GL+ N  C KL LKGNNI+  G E+L +++  N ++  + LEWN +G+  T F  FC+GL  N  LQ LDLRNNQI  +  + L  AL++NT L+ LD+R+N+IG+ GG+  L + + N++LS++ + GNN+P DI K+IE   + N E      E  +R+++ S       + E  R +Q  +L++ ID +   LR + + S   I QL++ L++RK     L A L++ ES+L + E +  +  A      +E       +  +L KEK+ R ++E R+LKE S+L+E++L  QNKV +L+    QQ   +FELK+ +    +E K K   +EE+ ++ + Q+ KE+   +E  + K++  ++ E    E   R+++ K +  R EL +EIS LK+   +D++  +E +   KQ++ AE++Q+  +L+E+++ +Q  KDE++S  N+QA  +  LQ  NS L +E+E+LK + E +  EL+ K    M+E+ KV++E    + KLESER    +L  K+   D+++ +    +R+    ++ E+  ++++L+ +E+E+ R+ E+E  RA  L +A+M Y   S
Sbjct:    1 MDEFRLTYVRLCKENHTEPQDVVVEKLKSLEQTGGKGRTTLDLSTHSLSPKTCAVLGKVLATDRNFTEVKFADCMLSDDAVKSLAQGLAYNGFCKKLDLKGNNIRGSGVEALGKMLQHNKSLISICLEWNALGMLETSFATFCDGLGANSVLQALDLRNNQINHEGGEELATALKRNTCLRALDLRWNNIGLLGGRAFLEMLKSNKSLSRLELAGNNVPSDITKSIETAIDNNAERQILSMEHQKRTHTLSQHI---KSVEKERSVQLSELMNEIDHKEELLRKTKRTSSHHIGQLQEALEDRKGAFNSLAAKLSMTESELVLAEQKANDYGAIVNHLKQEMTDAALIHQNELRKEKEDRAQVEMRYLKEVSDLEEKLLLSQNKVEDLDRKCRQQQEQIFELKEYVAHFQAELKLKGAQFEER-LQAERQHHKEIQRDLETARSKDIAHVKQEAEDVERSLRDRIQKMESHRLELEEEISRLKSNNMADKLLAEEQLQSAKQRIRAEEEQRHRQLEEKVRVLQTTKDELQSHCNQQAALVSELQSRNSGLTLEVENLKRRLEEMGHELADKNNYTMAEVGKVKIELNQVVNKLESERSLNAELREKLSQVDRELSDQLLRYRQAMEEKDRELVMVQEKLRARELEMQRQREEEVQRAQLLQSAMMSYITRS 667

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
Match: lrrc45 (leucine rich repeat containing 45 [Source:NCBI gene;Acc:103038066])

HSP 1 Score: 317.39 bits (812), Expect = 1.260e-97
Identity = 213/668 (31.89%), Postives = 377/668 (56.44%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKE-NDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E+F+  ++ LCK+  + P + ++  +Q    A       L LS +S++ E C VL    + DT F E+   DCMLS +  +L L GL  N     L LKGNN++  G E+L +L+ RN T+  L LEWN +G+   GF  FC GL +N  L  LDLRNNQI       L  AL++N+ L+ LD+R+N+IG+ GG+ +++  ++NR+L ++ + GNNIP DI+++IE     N +         SR+    K     +  +  Q L L++ ID+Q   +  S + S  ++ QL++ L ERK     L A L + E+ L M E +     D   +  L++ E +ER ++  + K ++  +  E + L+E +NL E+  QL+NK+ E E     Q + +FELK ++T + +E K ++   EE++   K + K+ + ++   + KE++ +      +E   +++++K +  R +L +E+S +K  I ++R Q +E++ K++ ++  E+ Q +S ++E+L+  +  +DE +S   +Q + I  L     +  IE+++L+ + +  ++ELSGK+   M+E+ +VR+E   +I  L++ER +Q  L  KI   +++++ +  S RE    + +E+ +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S
Sbjct:    1 MEDFRRAYMQLCKEAGVEPQESVLAQLQGTRAAAGG--TRLDLSGQSLTVESCAVLGRTLQKDTLFTELGLSDCMLSEEGAKLFLSGLCSNTTVKVLDLKGNNLRGAGAEALGKLLVRNKTLRRLVLEWNALGMWEEGFSIFCEGLASNSCLTQLDLRNNQINHQGAAELALALKRNSVLQELDLRWNNIGLLGGRALMDALQQNRSLLQLEMAGNNIPSDILRSIEQSMEHNSDRQSTMRERRSRTHVLSKEIQILKEEKGRQFLSLMETIDKQKDEMGRSSRNSSIRVGQLQEALSERKSTVNALTAKLQMTEAALAMSEQKVNNLGDLLTRVKLEKTELMER-HSKDIKKHQEDNVLHEGKLLREVNNLSEKNHQLKNKLEERERRCKSQQDQIFELKQELTNSTAELKLRLAQAEERLDMEKRRAKQALEDMDSLRQKEVDHINRHLEESERALQDRILKLEGQRIQLEEELSRVKAAIVTERAQAEEELGKVRTQVRLEEQQHLSSMEEKLRNARQARDEAQSHCTQQKQTIAELHARTGQQSIEMDALRRRIDEQQQELSGKEQEKMAEVARVRVELQEQIGHLQAERTAQSSLKEKIAALEREMKALSTSHREALLDKESEISSLLERLRMKEGEIQRMREDEAQRASFLQNAILTYVQGS 665

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Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKR-NNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKE-NDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPS 2040
            +E+F+  ++ LCK+  + P + ++  +Q    A       L LS +S++ E C VL    + DT F E+   DCMLS +  +L L GL  N     L LKGNN++  G E+L +L+ RN T+  L LEWN +G+   GF  FC GL +N  L  LDLRNNQI       L  AL++N+ L+ LD+R+N+IG+ GG+ +++  ++NR+L ++ + GNNIP DI+++IE     N +         SR+    K     +  +  Q L L++ ID+Q   +  S + S  ++ QL++ L ERK     L A L + E+ L M E +     D   +  L++ E +ER ++  + K ++  +  E + L+E +NL E+  QL+NK+ E E     Q + +FELK ++T + +E K ++   EE++   K + K+ + ++   + KE++ +      +E   +++++K +  R +L +E+S +K  I ++R Q +E++ K++ ++  E+ Q +S ++E+L+  +  +DE +S   +Q + I  L     +  IE+++L+ + +  ++ELSGK+   M+E+ +VR+E   +I  L++ER +Q  L  KI   +++++ +  S RE    + +E+ +L +RL+ +E E+ R  EDE  RAS L NA++ Y Q S
Sbjct:    1 MEDFRRAYMQLCKEAGVEPQESVLAQLQGTRAAAGG--TRLDLSGQSLTVESCAVLGRTLQKDTLFTELGLSDCMLSEEGAKLFLSGLCSNTTVKVLDLKGNNLRGAGAEALGKLLVRNKTLRRLVLEWNALGMWEEGFSIFCEGLASNSCLTQLDLRNNQINHQGAAELALALKRNSVLQELDLRWNNIGLLGGRALMDALQQNRSLLQLEMAGNNIPSDILRSIEQSMEHNSDRQSTMRERRSRTHVLSKEIQILKEEKGRQFLSLMETIDKQKDEMGRSSRNSSIRVGQLQEALSERKSTVNALTAKLQMTEAALAMSEQKVNNLGDLLTRVKLEKTELMER-HSKDIKKHQEDNVLHEGKLLREVNNLSEKNHQLKNKLEERERRCKSQQDQIFELKQELTNSTAELKLRLAQAEERLDMEKRRAKQALEDMDSLRQKEVDHINRHLEESERALQDRILKLEGQRIQLEEELSRVKAAIVTERAQAEEELGKVRTQVRLEEQQHLSSMEEKLRNARQARDEAQSHCTQQKQTIAELHARTGQQSIEMDALRRRIDEQQQELSGKEQEKMAEVARVRVELQEQIGHLQAERTAQSSLKEKIAALEREMKALSTSHREALLDKESEISSLLERLRMKEGEIQRMREDEAQRASFLQNAILTYVQGS 665

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
Match: nlrc3 (NLR family CARD domain containing 3 [Source:NCBI gene;Acc:103024894])

HSP 1 Score: 67.3958 bits (163), Expect = 3.909e-11
Identity = 53/187 (28.34%), Postives = 91/187 (48.66%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISG--TGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            +N  L  L L E S+  E  K ++   + ++T  E+  +   +     + + + L  N     L L+ N + ++G  +LA  +  NS++  L L+    G+S    G +     L+ N+TL  LDLR N IG    + L+ AL+ N +L+ L+++ NS+G+ G   I      N  L+ I + GN I
Sbjct:  649 SNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQ----GVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNLQENSLGMDGAIFIATALRGNHQLTYINLQGNGI 831

HSP 2 Score: 64.3142 bits (155), Expect = 3.381e-10
Identity = 58/199 (29.15%), Postives = 93/199 (46.73%), Query Frame = 1

Query:  196 MCKVLSECFR-HDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLIS-RNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            +C VL+   +  D   EE    +C+ S    +L+ + L     C KL ++ N  K+   E L  L+S ++  I  LSL      IS  G       L+ N+TL +LDL  N IG    + L EAL+ N  +  ++++ NSI   G + +  + + NR L+ + +  N I  D +K I     +N  + + N  SN   D
Sbjct:  417 VCAVLAYLLQVSDACAEETHLSNCLDSASLKRLLPQLL----YCSKLRMENNGFKDDAMELLGSLLSAKDCHIQFLSLA--DSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHLGD 609

HSP 3 Score: 64.3142 bits (155), Expect = 3.944e-10
Identity = 55/226 (24.34%), Postives = 100/226 (44.25%), Query Frame = 1

Query:  205 VLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKV----------------------------LDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
             L++    + T   +S +   +S   ++ +   L  N     L L+ N+I  +G +++AR +  NST+ +L L+WN + I           L +N ++Q+LDL+ N +G +    L  AL+ N++L V                            LD+R NSIG+ G K + +  + NR+L  + +  N++ MD    I      N +++  N + N   +   K
Sbjct:  614 ALAQALVVNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLQWNFMKIGAA--KALAQSLHSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNLQENSLGMDGAIFIATALRGNHQLTYINLQGNGIGESGAK 837

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
Match: nlrc3 (NLR family CARD domain containing 3 [Source:NCBI gene;Acc:103024894])

HSP 1 Score: 64.3142 bits (155), Expect = 3.608e-10
Identity = 58/199 (29.15%), Postives = 93/199 (46.73%), Query Frame = 1

Query:  196 MCKVLSECFR-HDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLIS-RNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            +C VL+   +  D   EE    +C+ S    +L+ + L     C KL ++ N  K+   E L  L+S ++  I  LSL      IS  G       L+ N+TL +LDL  N IG    + L EAL+ N  +  ++++ NSI   G + +  + + NR L+ + +  N I  D +K I     +N  + + N  SN   D
Sbjct:  417 VCAVLAYLLQVSDACAEETHLSNCLDSASLKRLLPQLL----YCSKLRMENNGFKDDAMELLGSLLSAKDCHIQFLSLA--DSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHLGD 609

HSP 2 Score: 63.929 bits (154), Expect = 5.486e-10
Identity = 57/247 (23.08%), Postives = 105/247 (42.51%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVL----------------------------DMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK 798
             N  L  L+L   S+S +  K L+   R +     ++ ++  +  +  + I   L +N    +L L  N + ++G  ++A  +  N  +  L L+WN + I           L +N ++Q+LDL+ N +G +    L  AL+ N++L VL                            D+R NSIG+ G K + +  + NR+L  + +  N++ MD    I      N +++  N + N   +   K
Sbjct:  621 VNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAA--KALAQSLHSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNLQENSLGMDGAIFIATALRGNHQLTYINLQGNGIGESGAK 865

HSP 3 Score: 62.003 bits (149), Expect = 1.832e-9
Identity = 54/214 (25.23%), Postives = 97/214 (45.33%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD 786
            N  +  + L   S+  E  + L+E  + +     ++ +   + PD ++ I E L  N     L +  N++ + G  +LA+ +  N T+  LSL+ N V  S  G       L +N+ L  L+LR N IG +  + +  ALQ+N+ L+ LD+  N +   G   I    + NR L  + +  N + +   K +    + N  I   + + N+  D
Sbjct:  538 NQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHLGDLGTVALAQALVVNHTLCTLSLQSNSV--SDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTLGD 749

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
Match: lrrc74a (leucine rich repeat containing 74A [Source:NCBI gene;Acc:103039030])

HSP 1 Score: 58.5362 bits (140), Expect = 1.776e-8
Identity = 48/159 (30.19%), Postives = 71/159 (44.65%), Query Frame = 1

Query:  277 DCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMD-------IIKNIENLA 732
            D  +   E  S N    +L L  N    +G E L ++++ N  I  L L WN + + G     FC GL  N TL+ LDL  N  G +    L EAL+ N  L  LD+  N I   G  ++    E N TL  + +  N++ ++       ++KN    A
Sbjct:  170 DDAKWFAEAFSSNYRVKELDLSHNQFSGKGGEYLGQMLANNEGIELLDLSWNHLRMKGA--VAFCAGLKVNVTLKQLDLSWNGFGNEGALALGEALKFNNTLVDLDLSNNRITNEGVGMLCRGLEANDTLRTLKLAYNSLTVEGALALIRVVKNTPKTA 326

HSP 2 Score: 52.7582 bits (125), Expect = 1.143e-6
Identity = 40/149 (26.85%), Postives = 65/149 (43.62%), Query Frame = 1

Query:  199 CKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNI 645
             K  +E F  +   +E+       S    + + + L++N     L L  N+++ +G  +    +  N T+  L L WN  G    G       L  N TL  LDL NN+I  +   ML   L+ N  L+ L + YNS+ V G   ++ +
Sbjct:  172 AKWFAEAFSSNYRVKELDLSHNQFSGKGGEYLGQMLANNEGIELLDLSWNHLRMKGAVAFCAGLKVNVTLKQLDLSWN--GFGNEGALALGEALKFNNTLVDLDLSNNRITNEGVGMLCRGLEANDTLRTLKLAYNSLTVEGALALIRV 318

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002444.1 (pep scaffold:Pmarinus_7.0:GL480979:320698:340261:-1 gene:ENSPMAG00000002230.1 transcript:ENSPMAT00000002444.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 2.926e-10
Identity = 39/177 (22.03%), Postives = 83/177 (46.89%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            N+ +  L LS+  +  E C+ LS   + +   EE++     +       +   L +N     L L GNN+ ++    L   +S N ++ +L +  N++G +G       + + N++TL+ LDL  +   ++    +  A+  N +++ L + +  +G+ G   +    ++NRTL  +
Sbjct:    1 NTVVTKLDLSDNWLQEEGCRHLSRMLKENCYIEELNVSSNRMGVGGAMALCSALRENSTITSLNLSGNNLTDEAARHLHNAMSVNRSLKELDMSHNRIGDAGA--MHVAHMIANSETLETLDLAWSLWRWNGSVAIAAAISVNRSVRWLSLAWTGVGIEGALALREALQRNRTLHHL 175

HSP 2 Score: 50.8322 bits (120), Expect = 7.036e-7
Identity = 42/172 (24.42%), Postives = 74/172 (43.02%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNR 660
            NS +  L LS  +++ E  + L      + + +E+      +       +   ++++     L L  +  +  G  ++A  IS N ++  LSL W  VGI G         L  N+TL  LDL + ++     + L   LQ N  L+ L +  N I   G   +L+  +KN+
Sbjct:   57 NSTITSLNLSGNNLTDEAARHLHNAMSVNRSLKELDMSHNRIGDAGAMHVAHMIANSETLETLDLAWSLWRWNGSVAIAAAISVNRSVRWLSLAWTGVGIEGA--LALREALQRNRTLHHLDLSSCRVDERGARALAAGLQTNVALRSLKLALNPIMAEGALALLSAIQKNK 226

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Sea Lamprey
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 52.7582 bits (125), Expect = 1.142e-7
Identity = 43/153 (28.10%), Postives = 62/153 (40.52%), Query Frame = 1

Query:  277 DCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISG--------------TGFDQFCNGLIN------------NKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKN 657
            D + L    L  N    +L L  N     G E L +L++ N T+ +L L WN + + G              T      NGL N            N  L  LDLRNN+IG    + L   L  N +L+VL + +N   V G  +++   + N
Sbjct:    1 DAVLLTFLLLQSNYSVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQLCFNIFTVEGALVLIKAVKVN 153

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Sea Lamprey
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 51.9878 bits (123), Expect = 1.674e-7
Identity = 43/153 (28.10%), Postives = 62/153 (40.52%), Query Frame = 1

Query:  277 DCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISG--------------TGFDQFCNGLIN------------NKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKN 657
            D + L    L  N    +L L  N     G E L +L++ N T+ +L L WN + + G              T      NGL N            N  L  LDLRNN+IG    + L   L  N +L+VL + +N   V G  +++   + N
Sbjct:    1 DAVLLTFLLLQSNYSVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQLCFNIFTVEGALVLIKAVKVN 153

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Match: EDO43196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ93])

HSP 1 Score: 81.6481 bits (200), Expect = 1.680e-16
Identity = 58/186 (31.18%), Postives = 90/186 (48.39%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  E    +++    ++T E++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:  144 TNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 327

HSP 2 Score: 81.6481 bits (200), Expect = 2.105e-16
Identity = 58/186 (31.18%), Postives = 90/186 (48.39%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  E    +++    ++T E++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:  116 TNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 299

HSP 3 Score: 80.8777 bits (198), Expect = 2.964e-16
Identity = 57/186 (30.65%), Postives = 89/186 (47.85%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  E    +++    ++T E++  +   +  +    I + L  N    KL L+GN I + G  ++A+ +  NST+  L LE N++G    G       L+ N TL+ LDL  N+IG +    + +AL  N+ L+ LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:    2 TNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDDGAIAIAKALMTNSTLEKLDLEGNKIGDEDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIG 187

HSP 4 Score: 80.1073 bits (196), Expect = 6.371e-16
Identity = 57/186 (30.65%), Postives = 90/186 (48.39%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  E    +++    ++T +++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:  200 TNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 383

HSP 5 Score: 79.7221 bits (195), Expect = 7.161e-16
Identity = 57/186 (30.65%), Postives = 90/186 (48.39%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  E    +++    ++T +++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:  172 TNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 355

HSP 6 Score: 76.6406 bits (187), Expect = 7.733e-15
Identity = 52/169 (30.77%), Postives = 83/169 (49.11%), Query Frame = 1

Query:  193 EMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            E    +++    ++T E++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:  105 EGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 271

HSP 7 Score: 75.0998 bits (183), Expect = 2.411e-14
Identity = 57/188 (30.32%), Postives = 90/188 (47.87%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPD--CLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIP 699
            TNS L  L L    +  +    +++    ++T E++  +   +  +      I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G   I      N TL K+ + GN I 
Sbjct:   58 TNSTLEKLDLEGNKIGDDGAIAIAKALMTNSTLEKLDLEGNKIGDEDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGA--IAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG 243

HSP 8 Score: 73.559 bits (179), Expect = 8.812e-14
Identity = 49/161 (30.43%), Postives = 80/161 (49.69%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSG 624
            TNS L  L L    +  E    +++    ++T +++  +   +  +    I + L  N    KL L+GN I ++G  ++A+ +  NST+  L LE N++G  G         L+ N TL+ LDL  N+IG +    + +AL  N+ LK LD+  N IG  G
Sbjct:  228 TNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGA--IAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEG 386

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Match: EDO35050 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SML2])

HSP 1 Score: 69.3218 bits (168), Expect = 2.254e-12
Identity = 44/183 (24.04%), Postives = 90/183 (49.18%), Query Frame = 1

Query:   64 FLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSI 612
            +L LC++E + PS   ++  ++          C++L    +  +  +V+++    +     ++  D  + P   Q +   LS NC    + L GN I+ +G  ++  ++  ++++  L+L   + GI+G    +FC G+  N  L+ L   +N +     ++L+EAL  NT L+ LD+ +N I
Sbjct:    1 YLELCEKENIAPSWRFLRECETE---------CVSLPHYGLGDKGVRVVAKVLEQNLFVNILNLFDNGIGPHGAQDLSRMLSVNCFITHMNLSGNMIRKEGIIAIGIMLQESASLVFLNLA--KCGINGKDMMEFCKGIATNPHLKSLIFHSNNLSDQGSRLLSEALASNTALETLDLSWNDI 172

HSP 2 Score: 50.8322 bits (120), Expect = 1.399e-6
Identity = 43/167 (25.75%), Postives = 69/167 (41.32%), Query Frame = 1

Query:  139 ATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLIL 639
            ATN  L  L     ++S +  ++LSE    +T  E +                             L  N+I+     +LA+ +  N TI +L L WN     G    Q+   L ++ +LQ LD+ N  I  D  +++ + L+ N NL+VL +  N    +G   IL
Sbjct:  129 ATNPHLKSLIFHSNNLSDQGSRLLSEALASNTALETLD----------------------------LSWNDIRPGAMATLAKGLRLNHTIQELDLSWNTFQSRGVIAVQWF--LTHSTSLQTLDISNCGIHLDGAEVIAKVLRANRNLQVLKLGRNPFQNAGVPCIL 265

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Match: EDO35561 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL68])

HSP 1 Score: 67.0106 bits (162), Expect = 4.661e-12
Identity = 56/204 (27.45%), Postives = 82/204 (40.20%), Query Frame = 1

Query:  142 TNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGT--------------------------GFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            TNS L  L L++ ++  E  K ++E    ++T +E    D  +  +    I   L  N    KL L    I+  G  +LAR      ++  L L  NQ+   G                           G     N L+ N TL+ LDL  N IG +  + + EAL  N+ LK L +  ++IG  G   I N    N TL K+
Sbjct:   64 TNSTLKILDLTKNNIGNEGAKAIAEALMTNSTLKEFDLCDTNIGDEGAIAIANALMTNSTLKKLYLHDYGIRAVGIAALARTQLHKPSLIGLDLSSNQISSKGAIAIAEMLSKNQLLETFRLCLYQIGDEGAIAIANALMTNSTLKKLDLEGNYIGDEGAKAIAEALMTNSTLKELHLYESNIGDEGAIAIANALMTNSTLKKL 267

HSP 2 Score: 63.5438 bits (153), Expect = 7.254e-11
Identity = 41/117 (35.04%), Postives = 60/117 (51.28%), Query Frame = 1

Query:  325 IKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            I L L  N I ++G  ++A ++S+N  +    L +NQ+G  G       N L  N TL++LDL  N IG +  + + EAL  N+ LK  D+   +IG  G   I N    N TL K+
Sbjct:   13 IDLDLSLNKISSKGAIAIAEMLSKNQLLETFRLSFNQIGDEGA--IAIANALKTNSTLKILDLTKNNIGNEGAKAIAEALMTNSTLKEFDLCDTNIGDEGAIAIANALMTNSTLKKL 127

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Match: EDO35563 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL71])

HSP 1 Score: 63.929 bits (154), Expect = 6.597e-12
Identity = 42/117 (35.90%), Postives = 61/117 (52.14%), Query Frame = 1

Query:  325 IKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKI 675
            I L L  N I ++GC ++A ++S+N  +    L +NQ+G  G       N L  N TL++LDL  N IG +  + +  AL  N+ LK L +  N+IG  G   I N    N TL K+
Sbjct:   24 IDLDLSLNKISSKGCIAIAEMLSKNQWLETFILSYNQIGDEGA--MSIANALKTNSTLKILDLTKNNIGNEGAKAIANALMTNSTLKKLHLCENNIGDEGAIAIANALMTNSTLKKL 138

HSP 2 Score: 49.2914 bits (116), Expect = 6.472e-7
Identity = 36/98 (36.73%), Postives = 50/98 (51.02%), Query Frame = 1

Query:  403 TITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            ++ DL L  N+  IS  G       L  N+ L+   L  NQIG +    +  AL+ N+ LK+LD+  N+IG  G K I N    N TL K+ +  NNI
Sbjct:   22 SLIDLDLSLNK--ISSKGCIAIAEMLSKNQWLETFILSYNQIGDEGAMSIANALKTNSTLKILDLTKNNIGNEGAKAIANALMTNSTLKKLHLCENNI 117

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Match: EDO39348 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAC5])

HSP 1 Score: 65.855 bits (159), Expect = 1.030e-11
Identity = 46/146 (31.51%), Postives = 74/146 (50.68%), Query Frame = 1

Query:  244 EISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILI 681
            E+  ++  + P+    + E L+ N     L L  N I+N+G  ++A+L+  N  ITDL++  N   +S +G D   N LI N TL  LD+  N    D+   LT  LQ    L  LD+R+N+     G  +  + +KN +L ++ I
Sbjct:    7 ELVMRNLGIGPEGAAAVAEILAGNSSVRVLDLSVNGIQNKGAFAVAQLLEHNQWITDLNISENN--LSKSGLDSIGNMLILNNTLTCLDVSRNSFTCDDIHFLTNVLQTADALLFLDLRHNAFKEKAGLYLGEMVKKNTSLRELYI 150

HSP 2 Score: 51.9878 bits (123), Expect = 2.913e-7
Identity = 47/184 (25.54%), Postives = 81/184 (44.02%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNI 696
            N+ L CL +S  S +C+    L+   +   T + + F D                         L+ N  K +    L  ++ +N+++ +L + WN  G  G      C GL  N++L++LD+  N+IG D    + E ++ N  L  L++  N I   G + I    E N TL ++L +G N+
Sbjct:   86 NNTLTCLDVSRNSFTCDDIHFLTNVLQ---TADALLFLD-------------------------LRHNAFKEKAGLYLGEMVKKNTSLRELYIGWNHFGDEGA--KHLCAGLQENRSLEILDICWNEIGRDGAGYIAEFIENNGRLVELNLDNNHITDHGLRSIARGLEVNETL-RLLKVGFNL 238

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Match: lrrc45 (leucine rich repeat containing 45 [Source:NCBI gene;Acc:101174918])

HSP 1 Score: 253.062 bits (645), Expect = 1.347e-73
Identity = 200/686 (29.15%), Postives = 374/686 (54.52%), Query Frame = 1

Query:   43 LENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK-RNNYEN----SRKLQT---------LDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGXXXXXXXXXXXXVFELKDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHEWNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQKLHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDXXXXXXXXXXXXXXXXXXXXXXSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDLISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDEKTRASALHNAVMQYCQPSIQSSFA 2058
            +E+ +  +L LCK+  + P + ++  +Q            L LS +S+S + C VL+     D  F ++S  DCMLS +  +++L GL  N     L +KGNN+++ G E L +L++RN T+  L LEWN +G+    F  FC+GL +N TL  LDLRNNQI       L  AL+++ +L+ LD+R+N++G+ GG+ +L   + N+++ K+ + GNNIP D +K IE  A  N             SDR    R N+      SR++QT         L L++ ID Q   +  S++ +  +I  L++ L+ERK   + L A L +AE+ L + E + +       +   E+E    + + +  KE++  +  E + L+E  NL E   QL++K  ELE     Q   +FELK ++  + +E K ++   ++++   K ++K+ + +    + KE+  +      +E + +E+++K +E R +L +E+S  K    ++R+  +E++ +++ +L  ++ + +S L+E+L++++    E++   ++Q + I  LQ  N +   E++  + + E L++EL+GK    ++E+ +V++E   +I  L++E  +Q  L +KI   +++++ + ++ RE    + +E+ +L ++L+ +E E+ R  EDE  RAS L +A+  Y Q S    F 
Sbjct:    1 MEDSRGLYLRLCKEGGVEPQEGVLDQLQEGSR--------LDLSGQSLSADTCSVLARAL-QDGAFTQVSLSDCMLSEEGAKILLSGLFGNTTVKSLDMKGNNLRSAGAEVLGKLLARNKTLCRLVLEWNALGVWEEAFSAFCDGLGSNNTLTHLDLRNNQISHHGAAALALALRRSGSLEELDLRWNNLGLLGGRSLLEALQSNKSMVKLKVAGNNIPSDPLKAIEQTAGHN-------------SDRQTTLRENHSRTQVLSREIQTLKEEKGRQFLSLMETIDRQKEEMGRSNRSASVQISHLQEALNERKSAVKALTAKLQMAEAALALSEQKNQSLGERLSRLEAEKEDEREKQSRRRKKEEEDSLLREGKLLREIQNLTETNGQLRSKGEELEQRCKSQQQQIFELKQELANSTAELKMRLAQADDRLEMEKRRSKQALEDSESLRQKEVEHVSRRLEESERQLQERVLKLEEQRIQLEEEVSKGKAACVTERVHAEEELGRVRSQLRLQEQEHVSLLEEKLRSVRSSLQEVQLHCSQQKQTISELQAKNGQQSAEMDGCRRRVEELQQELAGKDQERVAEVSRVKVELQEQIALLQAEMMAQGGLKAKISALERELKVLGSNHREALLDKESEISSLLEKLRLKEAEIQRIREDEAHRASCLQSAIRAYVQGSPLGHFG 664

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BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Match: ENSORLT00000033051.1 (pep primary_assembly:ASM223467v1:4:31968248:31976451:-1 gene:ENSORLG00000026968.1 transcript:ENSORLT00000033051.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 115.161 bits (287), Expect = 7.114e-26
Identity = 72/236 (30.51%), Postives = 124/236 (52.54%), Query Frame = 1

Query:   37 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNG 744
            M++E+ +  +L LCK+  + P + ++  +Q            L LS +S+S + C VL            +S  DCMLS +  +++L GL  +     L + GNN+++   E L +L++ N T++ L             F  FC+ L  N TL  LDLRNNQI       L  AL+++ +++ LD+R+N++G+ GG+ +L   + N+++ ++ + GNNIP D +K +E  A  N 
Sbjct:    1 MTVEDSRGLYLCLCKEGGVEPQEGVLDQLQEGSR--------LDLSGQSLSKDTCSVL------------VSLSDCMLSEEGAKVLLSGLFGDTTVKSLDMNGNNLRSARAEVLGKLLAPNKTLSRLE-----------AFSGFCDCLGINNTLTPLDLRNNQISPCGAAALVLALRRSGSVEELDLRWNNLGLLGGRSLLEALQSNKSMVRLKVAGNNIPSDTLKALEQTAGHNA 205

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Match: ENSORLT00000026816.1 (pep primary_assembly:ASM223467v1:4:31968248:31976451:-1 gene:ENSORLG00000026968.1 transcript:ENSORLT00000026816.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 111.694 bits (278), Expect = 8.643e-25
Identity = 70/236 (29.66%), Postives = 122/236 (51.69%), Query Frame = 1

Query:   37 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNG 744
            M++E+ +  +L LCK+  + P + ++  +Q            L LS +S+S + C VL+               DCMLS +  +++L GL  +     L + GNN+++   E L +L++ N T+ +              F  FC+ L  N TL  LDLRNNQI       L  AL+++ +++ LD+R+N++G+ GG+ +L   + N+++ ++ + GNNIP D +K +E  A  N 
Sbjct:    1 MTVEDSRGLYLCLCKEGGVEPQEGVLDQLQEGSR--------LDLSGQSLSKDTCSVLARAL------------DCMLSEEGAKVLLSGLFGDTTVKSLDMNGNNLRSARAEVLGKLLAPNKTLKE-------------AFSGFCDCLGINNTLTPLDLRNNQISPCGAAALVLALRRSGSVEELDLRWNNLGLLGGRSLLEALQSNKSMVRLKVAGNNIPSDTLKALEQTAGHNA 203

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Match: ENSORLT00000031050.1 (pep primary_assembly:ASM223467v1:4:31973141:31976451:-1 gene:ENSORLG00000026968.1 transcript:ENSORLT00000031050.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.145 bits (261), Expect = 2.110e-24
Identity = 71/236 (30.08%), Postives = 123/236 (52.12%), Query Frame = 1

Query:   37 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNG 744
            M++E+ +  +L LCK+  + P + ++  +Q            L LS +S+S + C VL            +S  DCMLS +  +++L GL  +     L + GNN+++   E L +L++ N T+ +              F  FC+ L  N TL  LDLRNNQI       L  AL+++ +++ LD+R+N++G+ GG+ +L   + N+++ ++ + GNNIP D +K +E  A  N 
Sbjct:    1 MTVEDSRGLYLCLCKEGGVEPQEGVLDQLQEGSR--------LDLSGQSLSKDTCSVL------------VSLSDCMLSEEGAKVLLSGLFGDTTVKSLDMNGNNLRSARAEVLGKLLAPNKTLKE-------------AFSGFCDCLGINNTLTPLDLRNNQISPCGAAALVLALRRSGSVEELDLRWNNLGLLGGRSLLEALQSNKSMVRLKVAGNNIPSDTLKALEQTAGHNA 203

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Match: ENSORLT00000040321.1 (pep primary_assembly:ASM223467v1:4:31968248:31976451:-1 gene:ENSORLG00000026968.1 transcript:ENSORLT00000040321.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 107.842 bits (268), Expect = 1.399e-23
Identity = 71/236 (30.08%), Postives = 123/236 (52.12%), Query Frame = 1

Query:   37 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNG 744
            M++E+ +  +L LCK+  + P + ++  +Q            L LS +S+S + C VL            +S  DCMLS +  +++L GL  +     L + GNN+++   E L +L++ N T+ +              F  FC+ L  N TL  LDLRNNQI       L  AL+++ +++ LD+R+N++G+ GG+ +L   + N+++ ++ + GNNIP D +K +E  A  N 
Sbjct:    1 MTVEDSRGLYLCLCKEGGVEPQEGVLDQLQEGSR--------LDLSGQSLSKDTCSVL------------VSLSDCMLSEEGAKVLLSGLFGDTTVKSLDMNGNNLRSARAEVLGKLLAPNKTLKE-------------AFSGFCDCLGINNTLTPLDLRNNQISPCGAAALVLALRRSGSVEELDLRWNNLGLLGGRSLLEALQSNKSMVRLKVAGNNIPSDTLKALEQTAGHNA 203

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Match: SMESG000060194.1 (SMESG000060194.1)

HSP 1 Score: 716.457 bits (1848), Expect = 0.000e+0
Identity = 355/356 (99.72%), Postives = 355/356 (99.72%), Query Frame = 1

Query:   37 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKD 1104
            MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCN LINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKD
Sbjct:    1 MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNSLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDERKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQLDKEKD 356

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Match: SMESG000023093.1 (SMESG000023093.1)

HSP 1 Score: 63.1586 bits (152), Expect = 5.287e-10
Identity = 63/256 (24.61%), Postives = 101/256 (39.45%), Query Frame = 1

Query:  130 AYHATNSKLYCLT---LSEKSMSCEM-------------CKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSDRNGK--RNNYENSRKLQTLDL 843
            A+    SKL+CLT   +S    +C M             C  L++C       +        +  D  ++I+  L D+   I+L    N+I ++G  +L ++++                              N  +L+VL + NN I     Q +  A++KNT LK+LDMR N I   GG+ I      N TL  I + GN +       +  + N N  +   +  +N      GK  +    N+R L  LDL
Sbjct:  240 AFDPIVSKLFCLTDLRISYDVKNCGMNFEWNIFQFTINDCLQLAKCVSAAKQLKVFHLTRSRVDCDRCRVIISHLLDHPALIELDFSHNHIGDRGARALGKILN------------------------------NRSSLEVLKISNNMIKTAGAQAIAYAVKKNTTLKILDMRLNRILDEGGQAICKALLTNETLININLAGNEMSEPTAAILAQVVNSNTSLVSIDLSNNRLGPDGGKQIQEGMTNNRSLLNLDL 465

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Match: SMESG000053819.1 (SMESG000053819.1)

HSP 1 Score: 59.6918 bits (143), Expect = 3.022e-9
Identity = 44/124 (35.48%), Postives = 55/124 (44.35%), Query Frame = 1

Query:  454 GFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILN-----------------------------IFEKNRTLSKILILGNNIPMDIIKNIENLANR 738
            G ++ C+ LI N+TL VLDL  N+I  D  ++L + L+ NT LKVLD+ YN I   G K I N                               E N TL KI I GN    D IK    L +R
Sbjct:  178 GMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHDQGIKAIANSLCYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDR 301

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Match: SMESG000006391.1 (SMESG000006391.1)

HSP 1 Score: 54.6842 bits (130), Expect = 1.470e-7
Identity = 47/171 (27.49%), Postives = 75/171 (43.86%), Query Frame = 1

Query:  145 NSKLYCLTLSEKSMSCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLCLKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLILNIFEKN 657
            N +L  L LS+          + +   + +  E ++F     S  CL     GL+     ++L L  N+I     +     ++ NST+  L+L WN +G S  G   F   L  N TL+ +D+ NN+I  +   +L   L  N  LK L +  N +  +G   IL+   KN
Sbjct:   35 NLQLSRLDLSQNVFDDRAAGFIGDLIANASKLEYLNFSKNKFSSHCLLAFGMGLTQTRQLVELDLSWNHITGNEMKHFCSGLADNSTLKVLNLSWNGLG-SIPGMQDFGKMLKTNTTLEEIDISNNRITTEGAVLLGRGLSVNCTLKTLKIGSNPMQTAGCYAILSTILKN 204

[Close]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Match: SMESG000053815.1 (SMESG000053815.1)

HSP 1 Score: 51.6026 bits (122), Expect = 1.656e-6
Identity = 44/124 (35.48%), Postives = 61/124 (49.19%), Query Frame = 1

Query:  367 CESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLINNKTLQVLDLRNNQIGFDNCQMLTEALQK-NTNLKVLDMRYNSIGVSGGKLILNIFEKNRTLSKILILGNNIPMDIIKNIENLAN 735
            C++L  LI+R+ T+ DLS       I+  G       L  N  L++LDL  N+I     Q +  +L+  NT LK L ++YN I   G K IL    +N TL KI I GN      I+   +L N
Sbjct:  244 CDAL--LINRSLTVLDLSCNR----ITSDGALHLAKVLKFNTPLEILDLGYNRIHDQGIQAIAGSLRYCNTRLKCLVIKYNEIEDEGLKAILTALHENSTLEKIYIWGNKFTSKFIELFVSLVN 361

The following BLAST results are available for this feature:

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Celegans
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Fly
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Sea Lamprey
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Yeast
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LRRC45	7.083e-78	29.57	leucine rich repeat containing 45 [Source:HGNC Sym...	[more]
NLRC3	1.395e-13	26.12	NLR family CARD domain containing 3 [Source:HGNC S...	[more]
NLRC3	1.727e-13	26.12	NLR family CARD domain containing 3 [Source:HGNC S...	[more]
LRRC74A	4.414e-11	29.00	leucine rich repeat containing 74A [Source:HGNC Sy...	[more]
NLRC3	2.104e-10	29.32	NLR family CARD domain containing 3 [Source:HGNC S...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc45	9.884e-95	32.40	leucine rich repeat containing 45 [Source:ZFIN;Acc...	[more]
lrrc45	8.494e-92	32.25	leucine rich repeat containing 45 [Source:ZFIN;Acc...	[more]
lrrc45	8.343e-91	32.10	leucine rich repeat containing 45 [Source:ZFIN;Acc...	[more]
lrrc45	4.399e-77	30.96	leucine rich repeat containing 45 [Source:ZFIN;Acc...	[more]
lrrc45	1.577e-65	28.68	leucine rich repeat containing 45 [Source:ZFIN;Acc...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pth2r	3.670e-65	28.93	parathyroid hormone 2 receptor [Source:Xenbase;Acc...	[more]
pth2r	2.301e-56	28.38	parathyroid hormone 2 receptor [Source:Xenbase;Acc...	[more]
pth2r	9.745e-54	27.51	parathyroid hormone 2 receptor [Source:Xenbase;Acc...	[more]
pth2r	1.139e-53	28.97	parathyroid hormone 2 receptor [Source:Xenbase;Acc...	[more]
hcn4	4.132e-12	37.27	hyperpolarization activated cyclic nucleotide gate...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lrrc45	1.689e-78	28.64	leucine rich repeat containing 45 [Source:MGI Symb...	[more]
Lrrc45	2.602e-57	30.86	leucine rich repeat containing 45 [Source:MGI Symb...	[more]
Lrrc45	5.794e-27	34.57	leucine rich repeat containing 45 [Source:MGI Symb...	[more]
Nlrc3	1.309e-11	28.33	NLR family, CARD domain containing 3 [Source:MGI S...	[more]
Nlrc3	2.873e-11	28.09	NLR family, CARD domain containing 3 [Source:MGI S...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5ZI11\|LRC45_CHICK	1.025e-81	29.54	Leucine-rich repeat-containing protein 45 OS=Gallu...	[more]
sp\|Q8CIM1\|LRC45_MOUSE	1.181e-77	28.64	Leucine-rich repeat-containing protein 45 OS=Mus m...	[more]
sp\|Q96CN5\|LRC45_HUMAN	3.402e-77	29.57	Leucine-rich repeat-containing protein 45 OS=Homo ...	[more]
sp\|Q7RTR2\|NLRC3_HUMAN	6.698e-13	26.12	NLR family CARD domain-containing protein 3 OS=Hom...	[more]
sp\|Q5DU56\|NLRC3_MOUSE	2.091e-10	28.09	Protein NLRC3 OS=Mus musculus OX=10090 GN=Nlrc3 PE...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3S1AUP5	3.394e-103	34.79	Uncharacterized protein OS=Elysia chlorotica OX=18...	[more]
A0A1S3IM07	1.772e-101	33.38	leucine-rich repeat-containing protein 45 isoform ...	[more]
A0A1S3INX5	1.842e-99	32.94	leucine-rich repeat-containing protein 45 isoform ...	[more]
A0A1S3IMD1	9.118e-99	32.21	leucine-rich repeat-containing protein 45 isoform ...	[more]
A0A2T7PVH9	9.712e-99	33.53	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc45	1.260e-97	31.89	leucine rich repeat containing 45 [Source:NCBI gen...	[more]
lrrc45	1.260e-97	31.89	leucine rich repeat containing 45 [Source:NCBI gen...	[more]
nlrc3	3.909e-11	28.34	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
nlrc3	3.608e-10	29.15	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
lrrc74a	1.776e-8	30.19	leucine rich repeat containing 74A [Source:NCBI ge...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSPMAT00000002444.1	2.926e-10	22.03	pep scaffold:Pmarinus_7.0:GL480979:320698:340261:-...	[more]
lrrc74a	1.142e-7	28.10	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]
lrrc74a	1.674e-7	28.10	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO43196	1.680e-16	31.18	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35050	2.254e-12	24.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35561	4.661e-12	27.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35563	6.597e-12	35.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39348	1.030e-11	31.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc45	1.347e-73	29.15	leucine rich repeat containing 45 [Source:NCBI gen...	[more]
ENSORLT00000033051.1	7.114e-26	30.51	pep primary_assembly:ASM223467v1:4:31968248:319764...	[more]
ENSORLT00000026816.1	8.643e-25	29.66	pep primary_assembly:ASM223467v1:4:31968248:319764...	[more]
ENSORLT00000031050.1	2.110e-24	30.08	pep primary_assembly:ASM223467v1:4:31973141:319764...	[more]
ENSORLT00000040321.1	1.399e-23	30.08	pep primary_assembly:ASM223467v1:4:31968248:319764...	[more]

BLAST of Leucine-rich repeat-containing protein 45 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000060194.1	0.000e+0	99.72	SMESG000060194.1	[more]
SMESG000023093.1	5.287e-10	24.61	SMESG000023093.1	[more]
SMESG000053819.1	3.022e-9	35.48	SMESG000053819.1	[more]
SMESG000006391.1	1.470e-7	27.49	SMESG000006391.1	[more]
SMESG000053815.1	1.656e-6	35.48	SMESG000053815.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30000732 ID=SMED30000732|Name=Leucine-rich repeat-containing protein 45|organism=Schmidtea mediterranea sexual|type=transcript|length=2262bp
TATATAAATCTTATATGATCAAAAATCAAATAAATCATGTCATTAGAAAA
TTTTAAAAACAGATTTCTTAATTTATGTAAACAAGAAAAATTAACTCCAT
CAGATTTTATTATCCAGTCTATACAGAGTGCTTATCATGCCACTAATTCA
AAACTGTATTGTCTGACATTATCAGAGAAAAGTATGAGCTGTGAGATGTG
TAAAGTTCTTTCCGAATGTTTTCGGCATGACACGACGTTTGAGGAAATTT
CTTTTAAAGATTGCATGCTATCACCAGACTGTCTACAGCTAATTTTGGAA
GGCCTTAGTGATAACTGCTGTTGCATTAAATTGTGCTTGAAGGGAAACAA
CATTAAAAATCAAGGCTGCGAATCGCTAGCGAGACTGATTAGTCGTAATA
GCACGATAACCGACTTGTCTCTTGAATGGAATCAAGTTGGAATCAGCGGA
ACTGGATTCGATCAGTTCTGTAACGGTTTAATTAATAATAAAACGCTTCA
GGTTTTGGATTTGAGAAACAATCAAATCGGATTCGATAATTGCCAAATGC
TCACAGAAGCATTACAGAAAAATACAAATCTGAAAGTCCTTGATATGCGA
TACAATTCAATTGGCGTCAGTGGAGGGAAACTTATACTGAACATATTCGA
AAAGAATCGAACCTTGTCAAAGATACTAATTCTCGGAAATAATATCCCAA
TGGATATAATCAAAAATATTGAAAATCTTGCCAACAGAAATGGAGAAATC
TCCGAAGCCAATGAAAGATCAAATTCCCGGTCGGATAGAAATGGGAAGCG
AAATAATTATGAGAATTCAAGAAAATTACAAACATTGGATTTGCTCGATA
GAATAGATGAACAAAACAGCGGATTACGAATGAGTGACAAGAAAAGCTTT
TCGAAAATAATTCAATTGGAGAAATTGCTAGATGAAAGAAAGCAGAAATG
CCAGCATCTGAATGCCAATCTAAATTTGGCTGAATCAAAACTAGAGATGT
ACGAAATACAATTCAAAGAAAACGATGCAAGTTTTCAGAAATCGTTAAAA
GAAAGAGAATATCTGGAGAGGCAATATAATTTACAGCTCGATAAAGAAAA
AGATTATCGGATTGAAATAGAAAAGCGATTTTTAAAAGAGCAATCAAATC
TACAAGAAAGGATATTACAACTCCAGAACAAAGTAGGAGAATTGGAAATA
AATCTCAACCAACAAAACAATAATGTATTCGAATTGAAAGACAAAATTAC
TTTGACAAATTCCGAATGTAAATCGAAAATTCTGGATTACGAAGAACAAA
TAATCAAACTAAAAGACCAAAATAAAAAAGAAATGCATGAAGTTATCGAA
CAGAAAGACAAAGAAATGAATAAAATGCGGCATGAATGGAATTTGAATGA
AGAAAAATGGCGAGAAAAACTCATAAAAAACGATGAGATCCGAGAAGAAC
TTAATCAAGAAATATCGAGTCTAAAAAATCAAATTTCTTCTGATAGAATA
CAACATGACGAAGATATCCATAAGATCAAGCAGAAACTCCACGCCGAACA
AGATCAGAAAATCAGTAAGCTTGATGAGCAACTCAAAACAATGCAAATCC
TAAAAGATGAAATCGAATCACAAAATAATCGACAGGCTCGAGAAATCGAA
ACATTACAAAAGGATAATTCGAAATTGAAAATTGAATTGGAAAGCTTAAA
AATCAAAAAAGAAAATTTGGAAGAGGAATTATCGGGAAAACAAGCCACAA
TGATGAGCGAAATAGAAAAGGTTCGTCTCGAATATATGCATCGAATCCAA
AAATTAGAAAGTGAAAGACAAAGTCAAGTTGATCTGATATCCAAAATCGA
GCATCAAGATAAACAAATTCAAGAGATGAGGAATTCCTTCAGAGAAGAAT
CGTATTCTCGAAACACAGAAATGCAAACTCTGAAAGATAGACTCAAAAAT
CAAGAAGTTGAGCTAAATCGACGCCATGAAGATGAAAAGACTCGGGCCAG
TGCGTTGCATAATGCGGTGATGCAATACTGTCAACCATCAATACAAAGCA
GTTTTGCTCTTAACAGCCGTGGTGACATGTAGCAAAACATGTGATGCCAG
AATCATTTAATTGGTTATTTGATTGAATAAATTCTCTATTTGTTTTTGTT
TGAGTTGATAAATTTGCTCACTCGAAATATTTATACATCCGGTTTTGTTC
TATTGCTGTATTGTATGTTGAATGGGCAGAGAATTGGAGCAGGTTTGGCT
GCTATGTGACAA

protein sequence of SMED30000732-orf-1

>SMED30000732-orf-1 ID=SMED30000732-orf-1|Name=SMED30000732-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=682bp
MSLENFKNRFLNLCKQEKLTPSDFIIQSIQSAYHATNSKLYCLTLSEKSM
SCEMCKVLSECFRHDTTFEEISFKDCMLSPDCLQLILEGLSDNCCCIKLC
LKGNNIKNQGCESLARLISRNSTITDLSLEWNQVGISGTGFDQFCNGLIN
NKTLQVLDLRNNQIGFDNCQMLTEALQKNTNLKVLDMRYNSIGVSGGKLI
LNIFEKNRTLSKILILGNNIPMDIIKNIENLANRNGEISEANERSNSRSD
RNGKRNNYENSRKLQTLDLLDRIDEQNSGLRMSDKKSFSKIIQLEKLLDE
RKQKCQHLNANLNLAESKLEMYEIQFKENDASFQKSLKEREYLERQYNLQ
LDKEKDYRIEIEKRFLKEQSNLQERILQLQNKVGELEINLNQQNNNVFEL
KDKITLTNSECKSKILDYEEQIIKLKDQNKKEMHEVIEQKDKEMNKMRHE
WNLNEEKWREKLIKNDEIREELNQEISSLKNQISSDRIQHDEDIHKIKQK
LHAEQDQKISKLDEQLKTMQILKDEIESQNNRQAREIETLQKDNSKLKIE
LESLKIKKENLEEELSGKQATMMSEIEKVRLEYMHRIQKLESERQSQVDL
ISKIEHQDKQIQEMRNSFREESYSRNTEMQTLKDRLKNQEVELNRRHEDE
KTRASALHNAVMQYCQPSIQSSFALNSRGDM*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0007264	small GTPase mediated signal transduction

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002032	epidermal cell
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR001611	Leu-rich_rpt
IPR032675	LRR_dom_sf

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0005856	cytoskeleton

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 509..607
None	No IPR available	COILS	Coil	Coil	coord: 362..403
None	No IPR available	COILS	Coil	Coil	coord: 408..450
None	No IPR available	COILS	Coil	Coil	coord: 462..489
None	No IPR available	COILS	Coil	Coil	coord: 626..653
None	No IPR available	COILS	Coil	Coil	coord: 291..325
None	No IPR available	SMART	SM00368	LRR_RI_2	coord: 93..120 e-value: 120.0 score: 2.5 coord: 151..178 e-value: 0.052 score: 22.7 coord: 179..206 e-value: 0.95 score: 17.3 coord: 121..150 e-value: 110.0 score: 2.8
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 241..258
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 239..261
None	No IPR available	PANTHER	PTHR23170	NY-REN-58 ANTIGEN	coord: 3..668
None	No IPR available	PANTHER	PTHR23170:SF3	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45	coord: 3..668
None	No IPR available	SUPERFAMILY	SSF52047	RNI-like	coord: 27..241
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 7..137 e-value: 2.0E-15 score: 58.3
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 138..268 e-value: 2.1E-19 score: 71.7
IPR001611	Leucine-rich repeat	PFAM	PF13516	LRR_6	coord: 178..200 e-value: 0.0077 score: 16.2 coord: 150..165 e-value: 0.35 score: 11.0

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Leucine-rich repeat-containing protein 45

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 15

Owlery

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